Corticospinal tract hyperintensity in patients with LGI1-antibody encephalitis and other central nervous system disorders with neuroglial antibodies
The frequency of corticospinal tract (CST) T2/FLAIR hyperintensity in disorders with neuroglial antibodies is unclear. Herein, we retrospectively reviewed brain MRIs of 101 LGI1-antibody encephalitis patients, and observed CST hyperintensity in 30/101(30%). It was mostly bilateral (93%), not associated with upper motor neuron signs/symptoms (7%), and frequently decreased over time (39%). In a systematic review including patients with other neuroglial antibodies, CST hyperintensity was reported in 110 with neuromyelitis optica (94%), myelin oligodendrocyte glycoprotein-associated disease (2%), Ma2-antibody (3%) and GAD65-an...
Source: Journal of Neuroimmunology - April 17, 2024 Category: Allergy & Immunology Authors: Lucia Campetella, Macarena Villagran Garc ía, Antonio Farina, Marie Benaiteau, Raffaele Iorio, Paolo Calabresi, Alberto Vogrig, Salvatore Versace, Nicolás Lundahl Ciano-Petersen, Elodie Bicilli Brotelle, Pierre Branger, Clotilde Verlut, Sophie Langner-L Tags: Short Communication Source Type: research
Marchiafava-Bignami disease: why not Marchiafava-Bignami-Carducci disease?
AbstractThe Marchiafava-Bignami disease has a curious backstory, namely, the publication in 1898 of theContribution to the Study of Nonsuppurative Encephalitis (Carducci A in Riv Psicol Psichiat Neuropat 8-9:125-135,1898), in which the neo-graduate Agostino Carducci described the disease that the pathologists Ettore Marchiafava and Amico Bignami would report 5 years later. (Source: Neurological Sciences)
Source: Neurological Sciences - April 16, 2024 Category: Neurology Source Type: research
Severe Herpes Simplex Encephalitis: an Unusual Presentation of IPEX
J Clin Immunol. 2024 Apr 16;44(4):100. doi: 10.1007/s10875-024-01702-z.NO ABSTRACTPMID:38625673 | DOI:10.1007/s10875-024-01702-z (Source: Herpes)
Source: Herpes - April 16, 2024 Category: Infectious Diseases Authors: Linda Rossini Claudia Maria Bonardi Silvia Bresolin Eva Trevisson Antonio Marzollo Source Type: research
Severe Herpes Simplex Encephalitis: an Unusual Presentation of IPEX
(Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - April 16, 2024 Category: Allergy & Immunology Source Type: research
Guide for the treatment of acute altered mental status. Iberoamerican Academy of Pediatric Neurology
Rev Neurol. 2024 Apr 16;78(8):229-235. doi: 10.33588/rn.7808.2023302.ABSTRACTIn pediatric patients, an acute altered mental status refers to a sudden and significant change in a child's brain function and level of consciousness. It may manifest as confusion, disorientation, agitation, lethargy or even a loss of consciousness. This condition is a medical emergency, and requires immediate evaluation and attention. There are several causes of acute altered mental status in children, including infections of the central nervous system such as meningitis or encephalitis, traumatic brain injury, metabolic disorders, seizures and ...
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: D L ópez F Espinel E Andrade A S Aguirre Source Type: research
Guide for the treatment of acute altered mental status. Iberoamerican Academy of Pediatric Neurology
Rev Neurol. 2024 Apr 16;78(8):229-235. doi: 10.33588/rn.7808.2023302.ABSTRACTIn pediatric patients, an acute altered mental status refers to a sudden and significant change in a child's brain function and level of consciousness. It may manifest as confusion, disorientation, agitation, lethargy or even a loss of consciousness. This condition is a medical emergency, and requires immediate evaluation and attention. There are several causes of acute altered mental status in children, including infections of the central nervous system such as meningitis or encephalitis, traumatic brain injury, metabolic disorders, seizures and ...
Source: Revista de Neurologia - April 15, 2024 Category: Neurology Authors: D L ópez F Espinel E Andrade A S Aguirre Source Type: research
First Isolation of Japanese Encephalitis Virus Genotype IV from Mosquitoes in Australia
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - April 15, 2024 Category: Infectious Diseases Authors: Alyssa T. Pyke Peter Burtonclay Nirdesh Poudel Wayne Ingall Neelima Nair Sonja Hall-Mendelin Scott B. Craig Craig Smith Wei Wang Jonathan M. Darbro Cassie C. Jansen Andrew F. van den Hurk Source Type: research
A Case Report of Autoimmune Encephalitis after Anti-SARS-CoV-2 Vaccination: The Role of Cognitive Impairments in the Diagnostic Process
CONCLUSIONS: In this case, a combination of neuroimaging testing, psychiatric evaluation, and neuropsychological assessment provided evidence for a diagnosis of autoimmune encephalitis post-vaccination. Early recognition is essential in order to prevent clinical progression; avoid intractable epilepsy, brain atrophy, and cognitive impairment; and improve prognosis.PMID:38614963 | DOI:10.1093/arclin/acae031 (Source: Archives of Clinical Neuropsychology)
Source: Archives of Clinical Neuropsychology - April 13, 2024 Category: Psychiatry & Psychology Authors: Marialaura Di Tella Ylenia Camassa Nahi Gabriella Paglia Giuliano Carlo Geminiani Source Type: research
A Case Report of Autoimmune Encephalitis after Anti-SARS-CoV-2 Vaccination: The Role of Cognitive Impairments in the Diagnostic Process
CONCLUSIONS: In this case, a combination of neuroimaging testing, psychiatric evaluation, and neuropsychological assessment provided evidence for a diagnosis of autoimmune encephalitis post-vaccination. Early recognition is essential in order to prevent clinical progression; avoid intractable epilepsy, brain atrophy, and cognitive impairment; and improve prognosis.PMID:38614963 | DOI:10.1093/arclin/acae031 (Source: Archives of Clinical Neuropsychology)
Source: Archives of Clinical Neuropsychology - April 13, 2024 Category: Psychiatry & Psychology Authors: Marialaura Di Tella Ylenia Camassa Nahi Gabriella Paglia Giuliano Carlo Geminiani Source Type: research
Phase 3 immunogenicity and safety study of a tick-borne encephalitis vaccine in healthy Japanese participants 1 year of age and older
CONCLUSIONS: TBE vaccine elicited robust immune responses in Japanese participants 1 year of age and older. The 3-dose regimen was safe and well tolerated, and findings were consistent with the known safety profile of this TBE vaccine.CLINICALTRIALS: gov: NCT04648241.PMID:38614954 | DOI:10.1016/j.vaccine.2024.03.071 (Source: Vaccine)
Source: Vaccine - April 13, 2024 Category: Allergy & Immunology Authors: Motoharu Yonekawa Tohru Watanabe Osamu Kogawara Chihiro Yoshii Masako Yamaji Masakazu Aizawa Wilhelm Erber Shuhei Ito Bogdan Jug Doris Koelch Richard de Solom Stephen P Lockhart Source Type: research
A Case Report of Autoimmune Encephalitis after Anti-SARS-CoV-2 Vaccination: The Role of Cognitive Impairments in the Diagnostic Process
CONCLUSIONS: In this case, a combination of neuroimaging testing, psychiatric evaluation, and neuropsychological assessment provided evidence for a diagnosis of autoimmune encephalitis post-vaccination. Early recognition is essential in order to prevent clinical progression; avoid intractable epilepsy, brain atrophy, and cognitive impairment; and improve prognosis.PMID:38614963 | DOI:10.1093/arclin/acae031 (Source: Archives of Clinical Neuropsychology)
Source: Archives of Clinical Neuropsychology - April 13, 2024 Category: Psychiatry & Psychology Authors: Marialaura Di Tella Ylenia Camassa Nahi Gabriella Paglia Giuliano Carlo Geminiani Source Type: research
The Association Between Children's Autism Spectrum Disorders and Central Nervous System Infections: Using a Nationwide Claims Database
This study aimed to examine this issue using an extensive national database. Utilizing JMDC medical claims database, we conducted a retrospective cohort study of children with at least three years of follow-up from birth, ensuring the mother's information was available. The focus was on the relationship between ASD incidence and exposures like viral meningitis/encephalitis, bacterial meningitis, and intrauterine infections. Cox proportional hazards was used to calculate hazard ratios (HRs) with covariates such as presence of maternal history of mental illness, preterm, low birth weight, respiratory and cardiac disorder, ep...
Source: Journal of Autism and Developmental Disorders - April 12, 2024 Category: Psychiatry Authors: Takanori Yanai Satomi Yoshida Koji Kawakami Source Type: research
The Association Between Children's Autism Spectrum Disorders and Central Nervous System Infections: Using a Nationwide Claims Database
This study aimed to examine this issue using an extensive national database. Utilizing JMDC medical claims database, we conducted a retrospective cohort study of children with at least three years of follow-up from birth, ensuring the mother's information was available. The focus was on the relationship between ASD incidence and exposures like viral meningitis/encephalitis, bacterial meningitis, and intrauterine infections. Cox proportional hazards was used to calculate hazard ratios (HRs) with covariates such as presence of maternal history of mental illness, preterm, low birth weight, respiratory and cardiac disorder, ep...
Source: Journal of Autism and Developmental Disorders - April 12, 2024 Category: Psychiatry Authors: Takanori Yanai Satomi Yoshida Koji Kawakami Source Type: research
Viruses, Vol. 16, Pages 599: Circulation of West Nile Virus and Usutu Virus in Europe: Overview and Challenges
n
West Nile Virus (WNV) and Usutu Virus (USUV) are both neurotropic mosquito-borne viruses belonging to the Flaviviridae family. These closely related viruses mainly follow an enzootic cycle involving mosquitoes as vectors and birds as amplifying hosts, but humans and other mammals can also be infected through mosquito bites. WNV was first identified in Uganda in 1937 and has since spread globally, notably in Europe, causing periodic outbreaks associated with severe cases of neuroinvasive diseases such as meningitis and encephalitis. USUV was initially isolated in 1959 in Swaziland and has also spread to Europe, primar...
Source: Viruses - April 12, 2024 Category: Virology Authors: Yannick Simonin Tags: Perspective Source Type: research
Haemorrhagic myelitis as a manifestation of MOG antibody-associated disease
We read with interest the recent article ‘MOG antibody-associated encephalitis in adult: clinical phenotypes and outcomes’ by Lee et al1 and the letter to the editor entitled ‘Acute haemorrhagic leucoencephalitis as clinical manifestation of MOG antibody-associated disease’ by Skarsta et al.2 In the first article, the authors illustrate three different phenotypes of MOG (myelin oligodendrocyte glycoprotein) antibody-associated encephalitis in 40 patients, including acute disseminated encephalomyelitis (ADEM) in 17 patients. They highlight the favourable outcome of these encephalitis cases following ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 12, 2024 Category: Neurosurgery Authors: Ciron, J., Biotti, D., Bost, C., Bonneville, F., Marignier, R. Tags: PostScript Source Type: research
