Defining clinical endpoints in limb girdle muscular dystrophy: a GRASP-LGMD study
This study is designed to devel... (Source: BMC Neurology)
Source: BMC Neurology - March 15, 2024 Category: Neurology Authors: Amy Doody, Lindsay Alfano, Jordi Diaz-Manera, Linda Lowes, Tahseen Mozaffar, Katherine D. Mathews, Conrad C. Weihl, Matthew Wicklund, Man Hung, Jeffrey Statland and Nicholas E. Johnson Tags: Study Protocol Source Type: research

Exploring the role of mitochondrial-associated and peripheral neuropathy genes in the pathogenesis of diabetic peripheral neuropathy
Diabetic peripheral neuropathy (DPN) is a prevalent and serious complication of diabetes mellitus, impacting the nerves in the limbs and leading to symptoms like pain, numbness, and diminished function. While ... (Source: BMC Neurology)
Source: BMC Neurology - March 13, 2024 Category: Neurology Authors: Ruojing Bai and Yuanyuan Luo Tags: Research Source Type: research

Unraveling the interplay between dyskinesia and overactive bladder symptoms in Parkinson ’s disease: a comprehensive cohort study based on the long-term follow-up database of Parkinson’s disease
Overactive bladder (OAB) and dyskinesia are frequent complications in patients with Parkinson ’s disease (PD). However, the correlation between OAB and dyskinesia has been insufficiently explored. The purpose o... (Source: BMC Neurology)
Source: BMC Neurology - March 12, 2024 Category: Neurology Authors: Hong Jin, Yiheng Du, Jiahui Yan, Jinru Zhang, Xiaoyu Cheng, Chengjie Mao, Jing Chen and Chun-feng Liu Tags: Research Source Type: research

Detection limitations of prion seeding activities in blood samples from patients with sporadic prion disease
Human prion diseases (HPDs) are fatal neurodegenerative disorders characterized by abnormal prion proteins (PrPSc). However, the detection of prion seeding activity in patients with high sensitivity remains ch... (Source: BMC Neurology)
Source: BMC Neurology - March 11, 2024 Category: Neurology Authors: Toshiaki Nonaka, Yasushi Iwasaki, Hiroyuki Horiuchi and Katsuya Satoh Tags: Research Source Type: research

Optimized MLPA workflow for spinal muscular atrophy diagnosis: identification of a novel variant, NC_000005.10:g.(70919941_70927324)del in isolated exon 1 of SMN1 gene through long-range PCR
Spinal muscular atrophy (SMA) is a rare autosomal recessive hereditary neuromuscular disease caused by survival motor neuron 1 (SMN1) gene deletion or mutation. Homozygous deletions of exon 7 in SMN1 result in 95... (Source: BMC Neurology)
Source: BMC Neurology - March 11, 2024 Category: Neurology Authors: Mei Yao, Liya Jiang, Yicheng Yu, Yiqin Cui, Yuwei Chen, Dongming Zhou, Feng Gao and Shanshan Mao Tags: Research Source Type: research

A systematic review and meta-analysis of clinical efficacy of early and late rehabilitation interventions for ischemic stroke
At present, stroke has become the first cause of death and disability among Chinese adults. With the coming of the aging population in China, the disease burden brought by stroke will be increasingly aggravate... (Source: BMC Neurology)
Source: BMC Neurology - March 8, 2024 Category: Neurology Authors: Xufang Wei, Shengtong Sun, Manyu Zhang and Zhenqiang Zhao Tags: Research Source Type: research

High thrombin-activatable fibrinolysis inhibitor expression in thrombi from stroke patients in elevated estrogen states
We described the histological compositio... (Source: BMC Neurology)
Source: BMC Neurology - March 7, 2024 Category: Neurology Authors: Tamanna Agarwal, Oana Madalina Mereuta, Sherief Ghozy, Jorge L Arturo Larco, Cem Bilgin, Ram Kadirvel, Waleed Brinjikji and David F Kallmes Tags: Research Source Type: research

Neuroanatomical and neurocognitive correlates of delusion in Alzheimer ’s disease and mild cognitive impairment
Neuropsychiatric symptoms and delusions are highly prevalent among people with dementia. However, multiple roots of neurobiological bases and shared neural basis of delusion and cognitive function remain to be... (Source: BMC Neurology)
Source: BMC Neurology - March 6, 2024 Category: Neurology Authors: Seyul Kwak, Hairin Kim, Keun You Kim, Da Young Oh, Dasom Lee, Gieun Nam and Jun-Young Lee Tags: Research Source Type: research

Association between serum triglycerides and stroke type, severity, and prognosis. Analysis in 6558 patients
Hypertriglyceridemia (HT) may increase the risk of stroke. Limited studies have shown that stroke severity and infarction size are smaller in patients with HT. We explored the relationship between triglyceride... (Source: BMC Neurology)
Source: BMC Neurology - March 5, 2024 Category: Neurology Authors: Naveed Akhtar, Rajvir Singh, Saadat Kamran, Sujatha Joseph, Deborah Morgan, Ryan Ty Uy, Sarah Treit and Ashfaq Shuaib Tags: Research Source Type: research

Relationship between glycated hemoglobin levels and three-month outcomes in acute ischemic stroke patients with or without diabetes: a prospective Korean cohort study
In patients experiencing acute ischemic stroke, there is ongoing debate surrounding the connection between chronic hyperglycemic status and their initial clinical outcomes. Our objective was to examine the con... (Source: BMC Neurology)
Source: BMC Neurology - March 4, 2024 Category: Neurology Authors: Changchun Cao, Tony Bowei Wang, Haofei Hu, Yong Han, Xiaohua Zhang and Yulong Wang Tags: Research Source Type: research

The associations between peripheral inflammatory and lipid parameters, white matter hyperintensity, and cognitive function in patients with non-disabling ischemic cerebrovascular events
The global prevalence of VCI has increased steadily in recent years, but diagnostic biomarkers for VCI in patients with non-disabling ischemic cerebrovascular incidents (NICE) remain indefinite. The primary ob... (Source: BMC Neurology)
Source: BMC Neurology - March 4, 2024 Category: Neurology Authors: Binghan Li, Zhengsheng Gu, Weisen Wang, Bingying Du, Chenghao Wu, Bin Li, Tianren Wang, Ge Yin, Xin Gao, Jingjing Chen, Xiaoying Bi, Hailing Zhang and Xu Sun Tags: Research Source Type: research

Expanded clinical phenotype and untargeted metabolomics analysis in RARS2-related mitochondrial disorder: a case report
RARS2-related mitochondrial disorder is an autosomal recessive mitochondrial encephalopathy caused by biallelic pathogenic variants in the gene encoding the mitochondrial arginyl-transfer RNA synthetase 2 (RARS2,... (Source: BMC Neurology)
Source: BMC Neurology - March 4, 2024 Category: Neurology Authors: Ameya S. Walimbe, Keren Machol, Stephen F. Kralik, Elizabeth A. Mizerik, Yoel Gofin, Mir Reza Bekheirnia, Charul Gijavanekar, Sarah H. Elsea, Lisa T. Emrick and Fernando Scaglia Tags: Case Report Source Type: research

Case identification of non-traumatic brain injury in youth using linked population data
This study aimed to present a method for case identification of non... (Source: BMC Neurology)
Source: BMC Neurology - March 2, 2024 Category: Neurology Authors: Rebecca F Slykerman, Betony E Clasby, Jimmy Chong, Kathryn Edward, Barry J Milne, Helen Temperton, Hiran Thabrew and Nicholas Bowden Tags: Research Source Type: research

Hand knob sign in osmotic demyelinating syndrome
We reported a patient ... (Source: BMC Neurology)
Source: BMC Neurology - March 2, 2024 Category: Neurology Authors: Noppachai Siranart, Pannathorn Nakaphan, Vasinee Viarasilpa, Prakit Anukoolwittaya and Pasin Hemachudha Tags: Case Report Source Type: research

Questionnaire-based study of COVID-19 vaccination induced headache: evidence of clusters of adverse events
The adverse events (AEs) after a Coronavirus disease 2019 (Covid-19) Pfizer-Biotech mRNA vaccination present a medical and epidemiological issue of increasing interest. Headache is the most frequent neurologic... (Source: BMC Neurology)
Source: BMC Neurology - March 2, 2024 Category: Neurology Authors: Qiao Zhou, Thomas Eggert, Ana Zhelyazkova, Alexander Chouk ér, Kristina Adorjan and Andreas Straube Tags: Research Source Type: research