Onset of Alzheimer disease in apolipoprotein ɛ4 carriers is earlier in butyrylcholinesterase K variant carriers
The authors sought to examine the impact of the K-variant of butyrylcholinesterase (BCHE-K) carrier status on age-at-diagnosis of Alzheimer disease (AD) in APOE4 carriers. (Source: BMC Neurology)
Source: BMC Neurology - April 9, 2024 Category: Neurology Authors: Roger M. Lane, Taher Darreh-Shori, Candice Junge, Dan Li, Qingqing Yang, Amanda L. Edwards, Danielle L. Graham, Katrina Moore and Catherine J. Mummery Tags: Research Source Type: research

Improving emotion perception in cochlear implant users: insights from machine learning analysis of EEG signals
Although cochlear implants can restore auditory inputs to deafferented auditory cortices, the quality of the sound signal transmitted to the brain is severely degraded, limiting functional outcomes in terms of... (Source: BMC Neurology)
Source: BMC Neurology - April 8, 2024 Category: Neurology Authors: Sebastien Paquette, Samir Gouin and Alexandre Lehmann Tags: Research Source Type: research

Streptococcus intermedius causing primary bacterial ventriculitis in a patient with severe periodontitis - a case report
Streptococcus intermedius is a member of the S. anginosus group and is part of the normal oral microbiota. It can cause pyogenic infections in various organs, primarily in the head and neck area, including brain ... (Source: BMC Neurology)
Source: BMC Neurology - April 5, 2024 Category: Neurology Authors: Satu Allonen, Janne Aittoniemi, Matti Vuorialho, Lassi N ärhi, Kari Panula, Risto Vuento and Jari Honkaniemi Tags: Case Report Source Type: research

Fabry disease in W162C mutation: a case report of two patients and a review of literature
Fabry disease is a multisystemic disorder characterized by deposition of globotriaosylceramide (Gb3) and its deacylated form in multiple organs, sometimes localized in specific systems such as the nervous or c... (Source: BMC Neurology)
Source: BMC Neurology - April 5, 2024 Category: Neurology Authors: Alessandro Furia, Raffaello Ditaranto, Elena Biagini, Vanda Parisi, Alex Incensi, Sara Parisini, Rocco Liguori and Vincenzo Donadio Tags: Case Report Source Type: research

Feasibility of a novel eHealth intervention for Parkinson ’s disease targeting motor-cognitive function in the home
Parkinson ’s disease (PD) drastically affects motor and cognitive function, but evidence shows that motor-cognitive training improves disease symptoms. Motor-cognitive training in the home is scarcely investiga... (Source: BMC Neurology)
Source: BMC Neurology - April 5, 2024 Category: Neurology Authors: Jenny Sedhed, Hanna Johansson, Nina Andersson, Elisabet Åkesson, Elke Kalbe, Erika Franzén and Breiffni Leavy Tags: Research Source Type: research

Evaluating the effect of rapamycin treatment in Alzheimer ’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol
Rapamycin is an inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, and preclinical data demonstrate that it is a promising candidate for a general gero- and neuroprotective treatment in hu... (Source: BMC Neurology)
Source: BMC Neurology - April 4, 2024 Category: Neurology Authors: Jonas E. Svensson, Martin Bolin, Daniel Thor, Pete A. Williams, Rune Brautaset, Marcus Carlsson, Peder S örensson, David Marlevi, Rubens Spin-Neto, Monika Probst, Göran Hagman, Anton Forsberg Morén, Miia Kivipelto and Pontus Plavén-Sigray Tags: Study Protocol Source Type: research

Guillain –Barre syndrome of acute motor axonal neuropathy (AMAN) type associated with herpes zoster: a case report
Guillain Barre syndrome (GBS) following Varicella zoster is a rare presentation and has only been reported in a few cases around the world. Of the reported cases, the type of GBS is not specified in the majori... (Source: BMC Neurology)
Source: BMC Neurology - April 3, 2024 Category: Neurology Authors: Leonard Wanninayake, Dilani Rajapaksha, Narmada Nair, Kamal Gunarathne and Udaya Ranawaka Tags: Case Report Source Type: research

Exploring vascular contributions to cognitive impairment and dementia (ENIGMA): protocol for a prospective observational study
Post-stroke cognitive impairment (PSCI) is common. However, the underlying pathophysiology remains largely unknown. Understanding the role of microvascular changes and finding markers that can predict PSCI, co... (Source: BMC Neurology)
Source: BMC Neurology - April 3, 2024 Category: Neurology Authors: Sigrid Breinholt Vestergaard, Andreas Gammelgaard Damsbo, Niels Lech Pedersen, Katrine Zachariassen, Kim Ryun Drasbek, Leif Østergaard, Grethe Andersen, Rikke Beese Dalby and Janne Kærgård Mortensen Tags: Study Protocol Source Type: research

Migraine treatment: quo vadis? Real-world data study (2015 –2022) in Spain
This study aimed to describe the management of migraine in Spain and identify improvement areas. (Source: BMC Neurology)
Source: BMC Neurology - April 2, 2024 Category: Neurology Authors: Patricia Pozo-Rosich, Mafalda Carmo, Alejandro Mu ñiz, Beatriz Armada, Carlota Moya-Alarcón and Julio Pascual Tags: Research Source Type: research

Treatment patterns and persistence on disease modifying therapies for multiple sclerosis and its associated factors
Effective interventions for Multiple Sclerosis require timely treatment optimization which usually involves switching disease modifying therapies. The patterns of prescription and the reasons for changing tre... (Source: BMC Neurology)
Source: BMC Neurology - April 2, 2024 Category: Neurology Authors: Sim ón Cárdenas-Robledo, Laura Estefanía Arenas-Vargas, Rubén Darío Arenas, Jorge Mario Gaspar-Toro, Ángela María Muñoz-Rosero, Aranza Helena Tafur-Borrero, Daniel Stiven Marín-Medina, Hernan Andrés Acosta-Fajardo, Claudia Guío-Sánchez and Lor Tags: Research Source Type: research

A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease
A ketogenic diet (KD) may benefit people with neurodegenerative disorders marked by mitochondrial depolarization/insufficiency, including Parkinson ’s disease (PD). (Source: BMC Neurology)
Source: BMC Neurology - April 1, 2024 Category: Neurology Authors: Alexander H. Choi, Melanie Delgado, Kong Y. Chen, Stephanie T. Chung, Amber Courville, Sara A. Turner, Shanna Yang, Kayla Airaghi, Irene Dustin, Patrick McGurrin, Tianxia Wu, Mark Hallett and Debra J. Ehrlich Tags: Research Source Type: research

Delays in Multiple Sclerosis diagnosis (DIMES): protocol for a multicentre, observational study of multiple sclerosis diagnostic pathways in the United Kingdom and Republic of Ireland
Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. Accumulating evidence indicates early diagnosis and early treatment improves long-term outcomes. However, the MS diagnost... (Source: BMC Neurology)
Source: BMC Neurology - March 28, 2024 Category: Neurology Authors: Ashvin Kuri, David E. Henshall, Daoud Chaudhry, Setthasorn Zhi Yang Ooi, Qiqi Zhang, Joela Mathews, Alison Thomson, David Rog, Jeremy Hobart and Ruth Dobson Tags: Study Protocol Source Type: research

Early ambulation protocol after diagnostic transfemoral cerebral angiography: an evidence-based practice project
No uniform consensus has been achieved regarding the ambulation protocol after transfemoral cerebral angiography (TFA). Until now, in most hospitals patients are prescribed 8-12 h strict immobilization along w... (Source: BMC Neurology)
Source: BMC Neurology - March 25, 2024 Category: Neurology Authors: Hao Liang, Richun Ye, Nana Song, Canhui Zhu, Miaolong Xu, Qiaoyu Ye, Lin Wei and Jiehan Chen Tags: Research Source Type: research

A systematic review of high impact CpG sites and regions for MGMT methylation in glioblastoma [A systematic review of MGMT methylation in GBM]
MGMT (O 6 -methylguanine-DNA methyltransferase) promoter methylation is a commonly assessed prognostic marker in glioblastoma (GBM). Epigenetic silencing of the MGMT gene by promoter methylation is associated wit... (Source: BMC Neurology)
Source: BMC Neurology - March 23, 2024 Category: Neurology Authors: David Gibson, Anh Huan Vo, Hannah Lambing, Prithanjan Bhattacharya, Peggy Tahir, Farid F. Chehab and Nicholas Butowski Tags: Research Source Type: research

Partial facial paralysis induced by sialolithiasis of the parotid gland: a case report
Facial paralysis due to parotid sialolithiasis-induced parotitis is a unusual clinical phenomenon that has not been reported in prior literature. This scenario can present a diagnostic challenge due to its rar... (Source: BMC Neurology)
Source: BMC Neurology - March 22, 2024 Category: Neurology Authors: Abhinav Suri, Stephen Avila, Christina Tan, Huda Alalami and Jennifer Harris Tags: Case Report Source Type: research