SARS-CoV-2 causes dysfunction in human iPSC-derived brain  microvascular endothelial cells potentially by modulating the Wnt signaling pathway

ConclusionThese findings suggest that SARS-CoV-2 infection causes BBB dysfunction via Wnt signaling. Thus, iPSC-BMELCs are a useful in vitro model for elucidating COVID-19 neuropathology and drug development.
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research