Haemorrhagic myelitis as a manifestation of MOG antibody-associated disease

We read with interest the recent article ‘MOG antibody-associated encephalitis in adult: clinical phenotypes and outcomes’ by Lee et al1 and the letter to the editor entitled ‘Acute haemorrhagic leucoencephalitis as clinical manifestation of MOG antibody-associated disease’ by Skarsta et al.2 In the first article, the authors illustrate three different phenotypes of MOG (myelin oligodendrocyte glycoprotein) antibody-associated encephalitis in 40 patients, including acute disseminated encephalomyelitis (ADEM) in 17 patients. They highlight the favourable outcome of these encephalitis cases following immunosuppressive treatment.1 Conversely, the second article reports on the case of a patient with acute haemorrhagic leucoencephalitis (also known as Hurst encephalitis, which is a haemorrhagic variant of ADEM) associated with MOG antibodies, with a highly aggressive clinical course and unfavourable prognosis.2 We would like to raise awareness of another unfavourable presentation of MOG antibody-associated disease (MOGAD), namely haemorrhagic myelitis. Case...
Source: Journal of Neurology, Neurosurgery and Psychiatry - Category: Neurosurgery Authors: Tags: PostScript Source Type: research