Retraction: MiR-34b inhibits the proliferation and promotes apoptosis in colon cancer cells by targeting Wnt/ β-catenin signaling pathway
Biosci Rep. 2024 May 29;44(5):BSR-2019-1799_RET. doi: 10.1042/BSR-2019-1799_RET.NO ABSTRACTPMID:38682477 | DOI:10.1042/BSR-2019-1799_RET (Source: Bioscience Reports)
Source: Bioscience Reports - April 29, 2024 Category: Biomedical Science Source Type: research
Comparative evaluation of hesperetin-loaded graphene oxide nanosheets (Hsp-GO) as a drug delivery system for colon cancer: synthesis and anticancer efficiency assessment
CONCLUSIONS: These study highlight the potential of Hsp-GO as a promising anti-cancer nano-drug for colon cancer therapy.PMID:38683228 | DOI:10.1007/s11033-024-09504-7 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 29, 2024 Category: Molecular Biology Authors: Arezou Sabbagh Hadi Mehdi Haghi Abolfazl Barzegar Mohammad Ali Hosseinpour Feizi Source Type: research
Comparative evaluation of hesperetin-loaded graphene oxide nanosheets (Hsp-GO) as a drug delivery system for colon cancer: synthesis and anticancer efficiency assessment
CONCLUSIONS: These study highlight the potential of Hsp-GO as a promising anti-cancer nano-drug for colon cancer therapy.PMID:38683228 | DOI:10.1007/s11033-024-09504-7 (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 29, 2024 Category: Molecular Biology Authors: Arezou Sabbagh Hadi Mehdi Haghi Abolfazl Barzegar Mohammad Ali Hosseinpour Feizi Source Type: research
CBX3 antagonizes IFN γ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity
EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00066-6. Online ahead of print.ABSTRACTAs an important immune stimulator and modulator, IFNγ is crucial for gut homeostasis and its dysregulation links to diverse colon pathologies, such as colitis and colorectal cancer (CRC). Here, we demonstrated that the epigenetic regulator, CBX3 (also known as HP1γ) antagonizes IFNγ signaling in the colon epithelium by transcriptionally repressing two critical IFNγ-responsive genes: STAT1 and CD274 (encoding Programmed death-ligand 1, PD-L1). Accordingly, CBX3 deletion resulted in chronic mouse colon inflammation, accompanied by u...
Source: Molecular Medicine - April 29, 2024 Category: Molecular Biology Authors: Yao Xiang Jorge Mata-Garrido Yuanji Fu Christophe Desterke Eric Batsch é Ahmed Hama ï Christine Sedlik Youssouf Sereme David Skurnik Abdelali Jalil Rachel Onifarasoaniaina Eric Frapy Jean-Christophe Beche Razack Alao Eliane Piaggio Laurence Arbibe Yunhu Source Type: research
LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients
CONCLUSIONS: A high-glucose environment can increase the tumor-promoting effect of ANRIL. ANRIL can promote glucose metabolism and colon cancer proliferation by downregulating miR-186-5p with subsequent upregulation of glycolysis enzymes expression and inhibition of apoptosis.PMID:38679999 | DOI:10.31557/APJCP.2024.25.4.1371 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hala Mosaad Sally M Shalaby Nevertety M Mahmoud Mona M Ahmed Alaa Fayed Hassan R Ashour Walaa Sarhan Source Type: research
M2 Macrophage Prominently Distributed in the Rat's Colon of DMH-Induced Inflammation Associated Colorectal Cancer
CONCLUSION: All of the rat's colon showing chronic inflammation that led to the tumorigenesis.PMID:38679997 | DOI:10.31557/APJCP.2024.25.4.1357 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Windy Arensya Omadhika Solikhah Solikhah Albertus Ari Adrianto Yekti Asih Purwestri Dewi Kartikawati Paramita Source Type: research
Implications of Pretreatment Serum Carcinoembryonic Antigen Levels and Perineural Invasion with Staging, Prognosis, and Management in Stage I-III Colon Cancer after Surgery: A Retrospective Cohort Study in the SEER Database
CONCLUSION: For postoperative patients with stage I-III colon cancer, our study indicated that the CP stage is a significant prognostic factor for CSS, which deserves more clinical attention. It's worth noting that including the CP stage in the AJCC TNM staging system of colon carcinoma is beneficial to the survival prediction and clinical treatment.PMID:38684496 | DOI:10.62713/aic.3296 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Qing Zhang Li Wang Ruirui Sun Jian Gao Tingting Liu Source Type: research
The Relationship of Microsatellite Instability with BRAF and p53 Mutations and Histopathological Parameters in Colorectal Adenocarcinoma
CONCLUSION: In colorectal adenocarcinoma, MSI and BRAF mutation are associated with parameters, indicating the host immune response and prognostic histopathological parameters, including tumor size and histological grade. The evaluation of MSI status and BRAF mutation can be particularly informative for predicting the prognosis and guiding the treatment management in poorly differentiated colorectal adenocarcinoma. Understanding the mechanisms of molecular carcinogenesis in colorectal carcinoma and organizing treatment algorithms based on molecular foundations will increase the success of the treatment.PMID:38684491 | DOI:...
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Özgecan Gündoğar Sibel Bekta ş Emine Y ıldırım Do ğan Gönüllü Source Type: research
Retraction: MiR-34b inhibits the proliferation and promotes apoptosis in colon cancer cells by targeting Wnt/ β-catenin signaling pathway
Biosci Rep. 2024 May 29;44(5):BSR-2019-1799_RET. doi: 10.1042/BSR-2019-1799_RET.NO ABSTRACTPMID:38682477 | DOI:10.1042/BSR-2019-1799_RET (Source: Bioscience Reports)
Source: Bioscience Reports - April 29, 2024 Category: Biomedical Science Source Type: research
Comparative evaluation of hesperetin-loaded graphene oxide nanosheets (Hsp-GO) as a drug delivery system for colon cancer: synthesis and anticancer efficiency assessment
CONCLUSIONS: These study highlight the potential of Hsp-GO as a promising anti-cancer nano-drug for colon cancer therapy.PMID:38683228 | DOI:10.1007/s11033-024-09504-7 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 29, 2024 Category: Molecular Biology Authors: Arezou Sabbagh Hadi Mehdi Haghi Abolfazl Barzegar Mohammad Ali Hosseinpour Feizi Source Type: research
Comparative evaluation of hesperetin-loaded graphene oxide nanosheets (Hsp-GO) as a drug delivery system for colon cancer: synthesis and anticancer efficiency assessment
CONCLUSIONS: These study highlight the potential of Hsp-GO as a promising anti-cancer nano-drug for colon cancer therapy.PMID:38683228 | DOI:10.1007/s11033-024-09504-7 (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 29, 2024 Category: Molecular Biology Authors: Arezou Sabbagh Hadi Mehdi Haghi Abolfazl Barzegar Mohammad Ali Hosseinpour Feizi Source Type: research
LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients
CONCLUSIONS: A high-glucose environment can increase the tumor-promoting effect of ANRIL. ANRIL can promote glucose metabolism and colon cancer proliferation by downregulating miR-186-5p with subsequent upregulation of glycolysis enzymes expression and inhibition of apoptosis.PMID:38679999 | DOI:10.31557/APJCP.2024.25.4.1371 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hala Mosaad Sally M Shalaby Nevertety M Mahmoud Mona M Ahmed Alaa Fayed Hassan R Ashour Walaa Sarhan Source Type: research
M2 Macrophage Prominently Distributed in the Rat's Colon of DMH-Induced Inflammation Associated Colorectal Cancer
CONCLUSION: All of the rat's colon showing chronic inflammation that led to the tumorigenesis.PMID:38679997 | DOI:10.31557/APJCP.2024.25.4.1357 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Windy Arensya Omadhika Solikhah Solikhah Albertus Ari Adrianto Yekti Asih Purwestri Dewi Kartikawati Paramita Source Type: research
Implications of Pretreatment Serum Carcinoembryonic Antigen Levels and Perineural Invasion with Staging, Prognosis, and Management in Stage I-III Colon Cancer after Surgery: A Retrospective Cohort Study in the SEER Database
CONCLUSION: For postoperative patients with stage I-III colon cancer, our study indicated that the CP stage is a significant prognostic factor for CSS, which deserves more clinical attention. It's worth noting that including the CP stage in the AJCC TNM staging system of colon carcinoma is beneficial to the survival prediction and clinical treatment.PMID:38684496 | DOI:10.62713/aic.3296 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Qing Zhang Li Wang Ruirui Sun Jian Gao Tingting Liu Source Type: research
The Relationship of Microsatellite Instability with BRAF and p53 Mutations and Histopathological Parameters in Colorectal Adenocarcinoma
CONCLUSION: In colorectal adenocarcinoma, MSI and BRAF mutation are associated with parameters, indicating the host immune response and prognostic histopathological parameters, including tumor size and histological grade. The evaluation of MSI status and BRAF mutation can be particularly informative for predicting the prognosis and guiding the treatment management in poorly differentiated colorectal adenocarcinoma. Understanding the mechanisms of molecular carcinogenesis in colorectal carcinoma and organizing treatment algorithms based on molecular foundations will increase the success of the treatment.PMID:38684491 | DOI:...
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Özgecan Gündoğar Sibel Bekta ş Emine Y ıldırım Do ğan Gönüllü Source Type: research
