LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients

CONCLUSIONS: A high-glucose environment can increase the tumor-promoting effect of ANRIL. ANRIL can promote glucose metabolism and colon cancer proliferation by downregulating miR-186-5p with subsequent upregulation of glycolysis enzymes expression and inhibition of apoptosis.PMID:38679999 | DOI:10.31557/APJCP.2024.25.4.1371

Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hala Mosaad Sally M Shalaby Nevertety M Mahmoud Mona M Ahmed Alaa Fayed Hassan R Ashour Walaa Sarhan Source Type: research