Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies
Conclusion
We found consistent evidence that high CRF is strongly associated with lower risk for a variety of mortality and incident chronic conditions in general and clinical populations. (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - May 2, 2024 Category: Sports Medicine Authors: Lang, J. J., Prince, S. A., Merucci, K., Cadenas-Sanchez, C., Chaput, J.-P., Fraser, B. J., Manyanga, T., McGrath, R., Ortega, F. B., Singh, B., Tomkinson, G. R. Tags: Open access, BJSM Reviews with MCQs, BJSM Systematic review Source Type: research
Infographic. All health professionals should talk about physical activity with patients
Regular physical activity contributes to the prevention and management of non-communicable diseases, including cardiovascular disease, stroke, diabetes and cancer, as well as improved mental health, sleep and cognitive function.1 Despite these benefits, populations worldwide are insufficiently active.2 Enabling people with the lowest levels of physical activity to become more active is where the greatest gains to public health will be achieved.3 Researchers, practitioners and policymakers are increasingly advocating for a systems approach to physical activity promotion. This should involve stakeholders across diverse secto...
Source: British Journal of Sports Medicine - May 2, 2024 Category: Sports Medicine Authors: Milton, K., Morris, J. L., McLaughlin, M., Cameron, A., Dewhurst, S., Gardner, S., Gomersall, S., Blackshaw, J. Tags: BJSM Infographic Source Type: research
Reply to ‘Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease’
Nature Reviews Cardiology, Published online: 02 May 2024; doi:10.1038/s41569-024-01029-7Reply to ‘Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease’ (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - May 2, 2024 Category: Cardiology Authors: Azita H. Talasaz Behnood Bikdeli Source Type: research
Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease
Nature Reviews Cardiology, Published online: 02 May 2024; doi:10.1038/s41569-024-01028-8Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - May 2, 2024 Category: Cardiology Authors: Jonatan W ärme Martin O. Sundqvist Stefan James Robin Hofmann Source Type: research
Molecules, Vol. 29, Pages 2100: Research Progress in Pharmacological Effects and Mechanisms of Angelica sinensis against Cardiovascular and Cerebrovascular Diseases
This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular...
Source: Molecules - May 2, 2024 Category: Chemistry Authors: Linlin Chen Bei Fan Fengzhong Wang Yang Song Xizhi Wang Ying Meng Yumin Chen Qing Xia Jing Sun Tags: Review Source Type: research
Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation
(Source: Journal of Clinical Investigation)
Source: Journal of Clinical Investigation - May 1, 2024 Category: Biomedical Science Authors: Theresa Failer, Michael Amponsah-Offeh, Aleš Neuwirth, Ioannis Kourtzelis, Pallavi Subramanian, Peter Mirtschink, Mirko Peitzsch, Klaus Matschke, Sems M. Tugtekin, Tetsuhiro Kajikawa, Xiaofei Li, Anne Steglich, Florian Gembardt, Annika C. Wegner, Christi Source Type: research
Frailty Assessment and Perioperative Adverse Cardiovascular Events After Noncardiac Surgery
Dr. Chandler
Clinical question: Can a frailty assessment tool be used to identify patients at higher risk for major adverse cardiac events (MACE) prior to noncardiac surgery?
Background: Studies have outlined the risk of increasing frailty on overall health outcomes and hospitalizations and as a possible risk factor for complications after noncardiac surgery. The association between frailty scores and perioperative MACE is limited.
Study design: Retrospective cohort study
Setting: Administrative data of patients aged ≥45 hospitalized for noncardiac surgeries between 2004 and 2014 in the U.S.
Synopsis: Using the Nati...
Source: The Hospitalist - May 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Cardiology In the Literature Source Type: research
Effectiveness of Applying Green Heart, a Smartphone-Based Self-management Intervention to Control Smoking: A Randomized Clinical Trial
CONCLUSION: Our results confirmed that complete adherence to the app for at least 24 weeks was linked to alterations in cigarette smoking behavior among CAD patients. Trial Registration Number: IRCT20221016056204N1.PMID:38690792 | DOI:10.34172/aim.2024.37 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - May 1, 2024 Category: Middle East Health Authors: Mojgan Ghavami Alireza Abdshah Ayat Ahmadi Diba Akbarzadeh Ali Mofidi Mahnaz Ashoorkhani Saeed Sadeghian Source Type: research
Identifying Risk Indicators of Cardiovascular Disease in Fasa Cohort Study (FACS): An Application of Generalized Linear Mixed-Model Tree
CONCLUSION: Given the superior performance of the GLMM tree compared with the standard tree and the lack of significant difference with the GLMM, using this model is suggested due to its simpler interpretation and fewer assumptions. Using updated statistical models for more accurate CVD prediction can result in more precise frameworks to aid in proactive patient detection planning.PMID:38690790 | DOI:10.34172/aim.2024.35 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - May 1, 2024 Category: Middle East Health Authors: Fariba Asadi Reza Homayounfar Mojtaba Farjam Yaser Mehrali Fatemeh Masaebi Farid Zayeri Source Type: research
Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research
Effects of Empagliflozin on vascular and skeletal mineralization in Hyperlipidemic mice
Vascul Pharmacol. 2024 Apr 29:107376. doi: 10.1016/j.vph.2024.107376. Online ahead of print.ABSTRACTCardiovascular disease and osteoporosis, major causes of morbidity and mortality, are associated with hyperlipidemia. Recent studies show that empagliflozin (EMPA), an inhibitor of sodium-glucose cotransporter-2 (SGLT2), improves cardiovascular health. In preclinical animal studies, EMPA mitigates vascular calcification in the males but its effects in the females are not known. Thus, we used female mice to test the effects of EMPA on calcification in the artery wall, cardiac function, and skeletal bone. By serial in vivo mic...
Source: Vascular Pharmacology - May 1, 2024 Category: Drugs & Pharmacology Authors: Sophia Kalanski Stuti Pradhan Andy Hon Yuxuan Xia Nora Safvati Juan Carlos Rivera Mimi Lu Linda L Demer Yin Tintut Source Type: research
NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration
CONCLUSION: These data indicate that supraphysiological levels of Testo increase the endothelial expression and activity of NOX4 to counterbalance the deleterious effects caused by Testo in endothelial function.PMID:38690939 | DOI:10.1152/ajpendo.00365.2023 (Source: Am J Physiol Endocri...)
Source: Am J Physiol Endocri... - May 1, 2024 Category: Endocrinology Authors: Juliano V Alves Rafael M da Costa Wanessa M C Awata Ariane Bruder-Nascimento Shubhnita Singh Rita C Tostes Thiago Bruder-Nascimento Source Type: research
The cardiovascular system at high altitude: A bibliometric and visualization analysis
CONCLUSION: Over the past 32 years, research on the cardiovascular system in high-altitude regions has been steadily increasing. Future research in this field may focus on areas such as hypoxia adaptation, metabolism, and cardiopulmonary exercise. Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.PMID:38690218 | PMC:PMC11056872 | DOI:10.4330/wjc.v16.i4.199 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Mao-Lin Zhao Zhong-Jie Lu Li Yang Sheng Ding Feng Gao Yuan-Zhang Liu Xue-Lin Yang Xia Li Si-Yi He Source Type: research
Hypoxia-inducible factor-1 α in myocardial infarction
World J Cardiol. 2024 Apr 26;16(4):181-185. doi: 10.4330/wjc.v16.i4.181.ABSTRACTHypoxia-inducible factor 1 (HIF1) has a crucial function in the regulation of oxygen levels in mammalian cells, especially under hypoxic conditions. Its importance in cardiovascular diseases, particularly in cardiac ischemia, is because of its ability to alleviate cardiac dysfunction. The oxygen-responsive subunit, HIF1α, plays a crucial role in this process, as it has been shown to have cardioprotective effects in myocardial infarction through regulating the expression of genes affecting cellular survival, angiogenesis, and metabolism. Furthe...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Ivana Škrlec Sergey N Kolomeichuk Source Type: research
NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration
CONCLUSION: These data indicate that supraphysiological levels of Testo increase the endothelial expression and activity of NOX4 to counterbalance the deleterious effects caused by Testo in endothelial function.PMID:38690939 | DOI:10.1152/ajpendo.00365.2023 (Source: American Journal of Physiology. Endocrinology and Metabolism)
Source: American Journal of Physiology. Endocrinology and Metabolism - May 1, 2024 Category: Physiology Authors: Juliano V Alves Rafael M da Costa Wanessa M C Awata Ariane Bruder-Nascimento Shubhnita Singh Rita C Tostes Thiago Bruder-Nascimento Source Type: research
