Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research
Elevated cardiovascular risk and acute events in hospitalized colon cancer survivors: A decade-apart study of two nationwide cohorts
CONCLUSION: Colon cancer survivors hospitalized 10 years apart in the United States showed an increased CVD risk with an increased risk of acute cardiovascular events (stroke 28%, PE 47%, arrhythmia 41%, and cardiac arrest 63%). It is vital to regularly screen colon cancer survivors with concomitant CVD risk factors to curtail long-term cardiovascular complications.PMID:38689632 | PMC:PMC11056864 | DOI:10.5306/wjco.v15.i4.548 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Rupak Desai Avilash Mondal Vivek Patel Sandeep Singh Shaylika Chauhan Akhil Jain Source Type: research
Endothelial dysfunction in breast cancer survivors on aromatase inhibitors: changes over time
CONCLUSIONS: We hypothesize that long-term use of AI can lead to persistent endothelial dysfunction, and further investigation is necessary. In our study, patients were on AI for approximately 5-10 years. As a result, we do not have data on whether these changes, such as EndoPAT® ratio and the elasticity of small and large arterial, are reversible with discontinuation of AI. These findings set the stage for a larger study to more conclusively determine the association between AI exposure and cardiovascular outcomes. Further studies should evaluate for multivariate associations withmodifiable risk factors for CV disease.PM...
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Adnan Shaaban Ashley Petersen Heather Beckwith Natalia Florea David A Potter Douglas Yee Rachel I Vogel Daniel Duprez Anne H Blaes Source Type: research
Adiposity, type 2 diabetes and atherosclerotic cardiovascular disease risk: Use and abuse of the body mass index
Atherosclerosis. 2024 Apr 14:117546. doi: 10.1016/j.atherosclerosis.2024.117546. Online ahead of print.ABSTRACTThe worldwide prevalence of individuals with an elevated body weight has increased steadily over the past five decades. Billions of research dollars have been invested to improve our understanding of the causes and consequences of having an elevated body weight. All this knowledge has, however, failed to influence populational body weight trajectories of most countries around the world. Research on the definition of "obesity" has also evolved. Body mass index (BMI), the most commonly used tool to make its diagnosi...
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Benoit J Arsenault Andr é C Carpentier Paul Poirier Jean-Pierre Despr és Source Type: research
Association between progression of coronary artery calcification and development of kidney failure with replacement therapy: Findings from KNOW-CKD study
CONCLUSIONS: CAC progression is associated with an increased risk of KFRT in patients with CKD. Our findings suggest that coronary atherosclerosis changes increase the risk of CKD progression.PMID:38692977 | DOI:10.1016/j.atherosclerosis.2024.117563 (Source: Atherosclerosis)
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Cheol Ho Park Hyung Woo Kim Jung Tak Park Tae Ik Chang Tae-Hyun Yoo Sue Kyung Park Kyu Beck Lee Ji Yong Jung Jong Cheol Jeong Kook-Hwan Oh Shin-Wook Kang Seung Hyeok Han KNOW-CKD (KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease) In Source Type: research
