Pediatric hypertension as an early manifestation of cardiovascular disease in children
J Bras Nefrol. 2024 May 3;46(4):e20230159. doi: 10.1590/2175-8239-JBN-2023-0159en. eCollection 2024.ABSTRACTIn adults, cardiovascular events associated with arterial hypertension (AH) have a major impact on morbidity and mortality. In light of recent findings, AH in children has been interpreted as early cardiovascular disease (CVD), while exposure to CV risk factors in children proves to be a predictor of subclinical CVD in adults. The American College of Cardiology/American Heart Association has recently updated the classifications for measuring blood pressure (BP) in adults and children. Primary AH in children is genera...
Source: Jornal Brasileiro de Nefrologia - May 3, 2024 Category: Urology & Nephrology Authors: Vera Hermina Kalika Koch Erika Arai Furusawa Source Type: research
Severe heart failure and intracardiac thrombosis: going beyond the appearance for diagnosis and treatments
We describe the case of a 45-year-old female affected by asthma and nasal polyposis who presented to the emergency department because of worsening dyspnea and paresthesia of the left lower limb. Comprehensive instrumental examinations revealed the presence of severe left ventricle dysfunction, intra-cardiac thrombus, deep vein thrombosis, pulmonary embolism, lung infiltrates, polyserositis, and neurological involvements. Finally, the patient was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA), formerly Churg-Strauss syndrome, a rare vasculitis of small-medium blood vessels with several organ involvement...
Source: Monaldi Archives for Chest Disease - May 3, 2024 Category: Respiratory Medicine Authors: Andrea Segreti Sara Mastroberardino Lorenzo Frau Alessandro Appetecchia Luca D'Antonio Danilo Ricciardi Gian Paolo Ussia Francesco Grigioni Source Type: research
The current paradigm of cardiac troponin increase among athletes
Monaldi Arch Chest Dis. 2024 Apr 30. doi: 10.4081/monaldi.2024.2878. Online ahead of print.ABSTRACTAlthough it is known that exercise improves cardiovascular health and extends life expectancy, a significant number of people may also experience an elevation in cardiac troponin levels as a result of exercise. For many years, researchers have argued whether exercise-induced cardiac troponin rises are a consequence of a physiological or pathological reaction and whether they are clinically significant. Differences in cardiac troponin elevation and cardiac remodeling can be seen between athletes participating in different type...
Source: Monaldi Archives for Chest Disease - May 3, 2024 Category: Respiratory Medicine Authors: Mihail Celeski Andrea Segreti Mariagrazia Piscione Luigi Maria Monticelli Giuseppe Di Gioia Chiara Fossati Gian Paolo Ussia Fabio Pigozzi Francesco Grigioni Source Type: research
The burden of alcohol-related cardiovascular complications in young and middle-aged adults: rising burden of atrial fibrillation and hypertensive heart disease
CONCLUSIONS: The impact of alcohol-associated atrial fibrillation and hypertensive heart disease has increased over the last decades. Regarding region, the burden in Europe and the rising burden in Asia, require immediate public health policy to lessen these cardiovascular complications from alcohol in young and middle-aged adults.PMID:38699921 | DOI:10.1080/00015385.2024.2346872 (Source: Acta Cardiologica)
Source: Acta Cardiologica - May 3, 2024 Category: Cardiology Authors: Pojsakorn Danpanichkul Phuuwadith Wattanachayakul Kwanjit Duangsonk Sorawit Ongsupankul Adivitch Sripusanapan Ekdanai Uawithya Juthipong Benjanuwattra Angkawipa Trongtorsak Surakit Nathisuwan Leenhapong Navaravong Source Type: research
Immuno-modulatory role of baicalin in atherosclerosis prevention and treatment: current scenario and future directions
Front Immunol. 2024 Apr 18;15:1377470. doi: 10.3389/fimmu.2024.1377470. eCollection 2024.ABSTRACTAtherosclerosis (AS) is recognized as a chronic inflammatory condition characterized by the accumulation of lipids and inflammatory cells within the damaged walls of arterial vessels. It is a significant independent risk factor for ischemic cardiovascular disease, ischemic stroke, and peripheral arterial disease. Despite the availability of current treatments such as statins, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, and lifestyle modifications for prevention, AS remains a leading cause of morbidity and ...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Li Wang Shenyi Huang Xiaolun Liang Junliang Zhou Yifan Han Jiangshan He Danping Xu Source Type: research
Exploring exercise-driven exerkines: unraveling the regulation of metabolism and inflammation
PeerJ. 2024 Apr 29;12:e17267. doi: 10.7717/peerj.17267. eCollection 2024.ABSTRACTExercise has many beneficial effects that provide health and metabolic benefits. Signaling molecules are released from organs and tissues in response to exercise stimuli and are widely termed exerkines, which exert influence on a multitude of intricate multi-tissue processes, such as muscle, adipose tissue, pancreas, liver, cardiovascular tissue, kidney, and bone. For the metabolic effect, exerkines regulate the metabolic homeostasis of organisms by increasing glucose uptake and improving fat synthesis. For the anti-inflammatory effect, exerki...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Nihong Zhou Lijing Gong Enming Zhang Xintang Wang Source Type: research
Palm oil as part of a high-fat diet: advances and challenges, or possible risks of pathology?
Nutr Rev. 2024 May 2:nuae038. doi: 10.1093/nutrit/nuae038. Online ahead of print.ABSTRACTNutritional status disorders have the most significant impact on the development of cardiovascular and oncologic diseases; therefore, the interest in the study of palm oil as among the leading components of nutrition has been increasing. The data examined in this review were sourced from the Scopus, SCIE (Web of Science), PubMed and PubMed Central, MEDLINE, CAPlus/SciFinder, and Embase databases; experts in the field; bibliographies; and abstracts from review analyses from the past 15 years. This review summarizes recent research data ...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Natalia Kurhaluk Source Type: research
Acoustic Delivery of Plasma Low-Density Lipoprotein into Liver via ApoB100-Targeted Microbubbles Inhibits Atherosclerotic Plaque Growth
ACS Appl Mater Interfaces. 2024 May 3. doi: 10.1021/acsami.4c00999. Online ahead of print.ABSTRACTAtherosclerosis is the main risk factor for cardiovascular disease, which accounts for the majority of mortality worldwide. A significantly increased plasma level of low-density lipoprotein cholesterol (LDL-C), surrounded by a monolayer of phospholipids, free cholesterol, and one apolipoprotein B-100 (ApoB-100) in the blood, plays the most significant role in driving the development of atherosclerosis. Commercially available cholesterol-lowering drugs are not sufficient for preventing recurrent cardiovascular events. Developin...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Zhenzhou Li Yi Zhou Manlin Lai Jingna Luo Fei Yan Source Type: research
Prospective Deep Learning-based Quantitative Assessment of Coronary Plaque by CT Angiography Compared with Intravascular Ultrasound
CONCLUSIONS: Artificial intelligence enabled CCTA quantification and characterization of atherosclerosis demonstrated strong agreement with IVUS reference standard measurements. This tool may prove effective for accurate evaluation of coronary atherosclerotic burden and cardiovascular risk assessment.[ClinicalTrails.gov identifier: NCT05138289].PMID:38700097 | DOI:10.1093/ehjci/jeae115 (Source: Atherosclerosis)
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Jagat Narula Thomas D Stuckey Gaku Nakazawa Amir Ahmadi Mitsuaki Matsumura Kersten Petersen Saba Mirza Nicholas Ng Sarah Mullen Michiel Schaap Jonathan Leipsic Campbell Rogers Charles A Taylor Harout Yacoub Himanshu Gupta Hitoshi Matsuo Sarah Rinehart Aki Source Type: research
Metabolic dysfunction-associated steatotic liver disease and atherosclerosis
Curr Diab Rep. 2024 May 3. doi: 10.1007/s11892-024-01542-6. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: To update information about the relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and atherosclerosis. This review emphasizes the potential mechanisms linking MASLD with atherosclerosis and the possible causal relationships between these conditions.RECENT FINDINGS: An increased risk of cardiovascular disease is related to MASLD. Several molecular, cellular, and metabolic mechanisms have been described to explain the development of atherothrombosis in MASLD patients. These include ...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Yulino Castillo-N úñez Paloma Almeda-Valdes Guillermo Gonz ález-Gálvez Mar ía Del Rosario Arechavaleta-Granell Source Type: research
Assessment of Native Myocardial T1 Mapping for Early Detection of Anthracycline-Induced Cardiotoxicity in Patients with Cancer: a Systematic Review and Meta-analysis
Cardiovasc Toxicol. 2024 May 3. doi: 10.1007/s12012-024-09866-1. Online ahead of print.ABSTRACTAnthracycline antibiotic is one of the most effective anti-tumor drugs used to manage certain types of breast cancers, lymphomas, and leukemias. However, anthracyclines induce a dose-dependent cardiotoxicity that may progress to heart failure. Thus, using a sensitive predictor of early cardiac dysfunction in patients treated with anthracyclines can help detect subclinical cardiac dysfunction early and help initiate interventions to protect these patients. Among parameters of myocardial measure, cardiac magnetic resonance (CMR)-me...
Source: Cardiovascular Toxicology - May 3, 2024 Category: Cardiology Authors: Amira A Mohamed Layla Y Elmancy Sara M Abulola Sara A Al-Qattan Mohamed Izham Mohamed Ibrahim Zaid H Maayah Source Type: research
Clinical Characteristics of EGPA Patients in Comparison to GPA Subgroup with Increased Blood Eosinophilia from POLVAS Registry
CONCLUSION: Cardiovascular symptoms were more prevalent in the ANCA-negative subset than in the MPO-ANCA-positive one. Since EGPA and GPE HE share similarities in clinics, diagnostic misleading may result in an inappropriate therapeutic approach. Further studies are needed to optimize their differentiation and tailored therapy, including biologics.PMID:38699219 | PMC:PMC11065486 | DOI:10.1155/2024/4283928 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - May 3, 2024 Category: Allergy & Immunology Authors: Anna Drynda Agnieszka Padjas Krzysztof W ójcik Rados ław Dziedzic Grzegorz Biedro ń Katarzyna Wawrzycka-Adamczyk Anna W łudarczyk Joanna Wila ńska Jacek Musia ł Zbigniew Zdrojewski Zenobia Czuszy ńska Anna Masiak Maria Majdan Rados ław Jeleniewicz Source Type: research
The Incidence of Winged Scapula after Thoracic Cancer Surgery: A Prospective Cohort Study
CONCLUSION: The incidence of WS was similar to the literature. As WS incidence is underdiagnosed, assessment and correct education about possible deficits or impairments should be improved. Moreover, when a minimally invasive approach is not planned, it is a good clinical practice to discuss surgical strategies with surgeons to reduce this deficit.PMID:38698601 | DOI:10.1055/s-0044-1786196 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - May 3, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Luiz Felipe Nevola Teixeira Fabio Sandrin Ruy Fernando Kuenzer Caetano da Silva Francesco Petrella Luca Bertolaccini Maria Claudia Simoncini Lorenzo Spaggiari Source Type: research
Pulmonary Arterial Anatomical Patterns: a Classification Scheme Based on Lobectomy and 3D-CTBA
CONCLUSION: The 3D-CTBA technique enables us to adequately assess the anatomy of the pulmonary arteries. Moreover, we provide a practical classification scheme of pulmonary arterial anatomical patterns based on lobectomy and 3D-CTBA. Our data can be used by clinicians in the teaching of pulmonary artery anatomy and the preoperative preparation for anatomical lobectomy.PMID:38698602 | DOI:10.1055/s-0044-1786195 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - May 3, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Zhuolin Xie Xinyu Zhu Feifei Li Jun Zhao Chang Li Source Type: research
Seeking ways to address non ‐cardiovascular death in patients with heart failure
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - May 3, 2024 Category: Cardiology Authors: Yudai Fujimoto,
Yuya Matsue Tags: Invited Editorial Source Type: research
