Computed Tomography-Assessed Sarcopenia Predicts Mortality in Kidney Transplant Candidates
CONCLUSIONS: Sarcopenia was ~5 times more frequent in patients with end-stage renal disease than in healthy controls and was positively correlated with the prognostic nutritional index. Sarcopenia was an independent risk factor for mortality in patients on transplant waiting lists.PMID:38695590 | DOI:10.6002/ect.2023.0050 (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2024 Category: Transplant Surgery Authors: Harun Coban Dilek Barutcu Atas Murat Tugcu Meltem Kursun Canan Cimsit Ebru Asicioglu Hakki Arikan Serhan Tuglular Arzu Velioglu Source Type: research
Regulatory bodies and health care systems should systematically evaluate the safety and cost-effectiveness of new cardiovascular treatments in health care registries using prospectively designed protocols
Scand Cardiovasc J. 2024 Dec;58(1):2343383. doi: 10.1080/14017431.2024.2343383. Epub 2024 May 2.NO ABSTRACTPMID:38695202 | DOI:10.1080/14017431.2024.2343383 (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 2, 2024 Category: Cardiology Authors: Bj örn Redfors Source Type: research
Atrial fibrillation incidence after coronary artery bypass graft surgery and percutaneous coronary intervention: the prospective AFAF cohort study
Conclusion. New-onset atrial fibrillation during 30 days of follow-up was rare after percutaneous coronary intervention but common after coronary artery bypass grafting. A prolonged uninterrupted heart rhythm monitoring strategy identified additional patients in both groups with new-onset atrial fibrillation after discharge.PMID:38695238 | DOI:10.1080/14017431.2024.2347297 (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 2, 2024 Category: Cardiology Authors: Anders Wickbom Espen Fengsrud Joakim Alfredsson Johan Engdahl Torbj örn Kalm Anders Ahlsson Source Type: research
Should varicocele screening be conducted in men diagnosed with chronic venous insufficiency? A prospective study
CONCLUSIONS: There is a significant association between left GSV diameter and varicocele (p = 0.004). Varicocele screening can be carried out with 71.4% sensitivity in adult male patients with a left GSV diameter of 5.35 cm and above. Both cardiovascular surgeons and radiologists can conduct varicocele screening by measuring pampiniform veins in patients with a left GSV diameter of 5.35 cm and above. This approach has the potential to reduce the incidence of varicocele and associated infertility.PMID:38693978 | PMC:PMC11059024 | DOI:10.5114/kitp.2024.138486 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Ferit Çetinkaya Kamil Do ğan Ay şe Taş Source Type: research
Combining echocardiography and fluoroscopy imaging in real time for left atrial appendage occlusion - single center experience from Poland
CONCLUSIONS: This study marks the inaugural application of FI in Polish LAAO procedures. FI, offering enhanced visualization and reduced procedure times, holds promise in improving patient safety and treatment efficacy. We recommend its consideration as a standard visualization technique for LAAO procedures.PMID:38693977 | PMC:PMC11059017 | DOI:10.5114/kitp.2024.138575 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Marian Burysz Jakub Batko Michalina Helena Malec-Litwinowicz Mariusz Kowalewski Rados ław Adam Litwinowicz Aleksandra Burysz Łukasz Graczykowski Wojciech Olejek Source Type: research
Should varicocele screening be conducted in men diagnosed with chronic venous insufficiency? A prospective study
CONCLUSIONS: There is a significant association between left GSV diameter and varicocele (p = 0.004). Varicocele screening can be carried out with 71.4% sensitivity in adult male patients with a left GSV diameter of 5.35 cm and above. Both cardiovascular surgeons and radiologists can conduct varicocele screening by measuring pampiniform veins in patients with a left GSV diameter of 5.35 cm and above. This approach has the potential to reduce the incidence of varicocele and associated infertility.PMID:38693978 | PMC:PMC11059024 | DOI:10.5114/kitp.2024.138486 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Ferit Çetinkaya Kamil Do ğan Ay şe Taş Source Type: research
Combining echocardiography and fluoroscopy imaging in real time for left atrial appendage occlusion - single center experience from Poland
CONCLUSIONS: This study marks the inaugural application of FI in Polish LAAO procedures. FI, offering enhanced visualization and reduced procedure times, holds promise in improving patient safety and treatment efficacy. We recommend its consideration as a standard visualization technique for LAAO procedures.PMID:38693977 | PMC:PMC11059017 | DOI:10.5114/kitp.2024.138575 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Marian Burysz Jakub Batko Michalina Helena Malec-Litwinowicz Mariusz Kowalewski Rados ław Adam Litwinowicz Aleksandra Burysz Łukasz Graczykowski Wojciech Olejek Source Type: research
Early-life exposures and long-term health: adverse gestational environments and the programming of offspring renal and vascular disease
Am J Physiol Renal Physiol. 2024 May 2. doi: 10.1152/ajprenal.00383.2023. Online ahead of print.ABSTRACTAccording to the Developmental Origins of Health and Disease (DOHaD) hypothesis, exposure to certain environmental influences during early life may be a key determinant of fetal development and short- and long-term offspring health. Indeed, adverse conditions encountered during the fetal, perinatal, and early childhood stages can alter normal development and growth, as well as put the offspring at elevated risk of developing long-term health conditions in adulthood, including chronic kidney disease (CKD) and cardiovascul...
Source: Am J Physiol Renal P... - May 2, 2024 Category: Urology & Nephrology Authors: Zo é Oulerich Amanda N Sferruzzi-Perri Source Type: research
Succinylation of Park 7 Activates a Protective Metabolic Response to Acute Kidney Injury
In this study we show in vitro and in vivo that Park7 has a crucial role in protection from AKI, and upregulated peroxisome activity. These data in combination with published results of Park7's protective role in cardiovascular damage and chronic kidney disease lead us to hypothesize that succinylation of Park7 may ameliorate oxidative damage resulting from AKI and prevent disease progression. This novel mechanism provides a potential therapeutic mechanism that can be targeted.PMID:38695076 | DOI:10.1152/ajprenal.00062.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - May 2, 2024 Category: Urology & Nephrology Authors: Katherine Pfister Victoria Young Brendon Frankel Anne Silva Barbosa Jordan Burton Joanna Bons Bob Zhang Takuto Chiba Rebecca Uhlean Eric Goetzman Birgit Schilling Sunder Sims-Lucas Source Type: research
Iron chelators: as therapeutic agents in diseases
Ann Med Surg (Lond). 2024 Mar 19;86(5):2759-2776. doi: 10.1097/MS9.0000000000001717. eCollection 2024 May.ABSTRACTThe concentration of iron is tightly regulated, making it an essential element. Various cellular processes in the body rely on iron, such as oxygen sensing, oxygen transport, electron transfer, and DNA synthesis. Iron excess can be toxic because it participates in redox reactions that catalyze the production of reactive oxygen species and elevate oxidative stress. Iron chelators are chemically diverse; they can coordinate six ligands in an octagonal sequence. Because of the ability of chelators to trap essentia...
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Zohreh Salimi Mehdi Afsharinasab Mehdi Rostami Yaser Eshaghi Milasi Seyedeh Fatemeh Mousavi Ezmareh Fariba Sakhaei Maryam Mohammad-Sadeghipour Sayyed Mehdi Rasooli Manesh Zatollah Asemi Source Type: research
Smoking behaviour in post-acute myocardial infarction patients: cross-sectional study
CONCLUSION: Multinomial logistic regression analysis identified current smoking as a significant predictor of intention to quit in the preparation and contemplation stages. Overall, this study underscores the importance of considering smoking behaviour when evaluating the intention to quit smoking post-MI and highlights the need for tailored interventions and support strategies to address smoking cessation in this population. These findings offer valuable insights for the development of effective strategies aimed at reducing persistent smoking following MI and improving patient outcomes.PMID:38694391 | PMC:PMC11060240 | DO...
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Waseem Barkhurdar Arif Hussain Muhammad Saqlain Rida Zahra Irshad Hussain Muhammad Saqib Hassan Mumtaz Source Type: research
Efficacy and outcomes of antiplatelet therapy versus oral anticoagulants in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis
CONCLUSIONS: Although the risk of valve thrombosis increased in patients receiving APT, the risk of other endpoints was comparable between the two groups.PMID:38694361 | PMC:PMC11060210 | DOI:10.1097/MS9.0000000000001908 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Aman Goyal Fatima Qayyum Abbasi Muhammad Daoud Tariq Sai Gautham Kanagala Mah I Kan Changez Darsh Safi Jawad Basit Samia Aziz Sulaiman Mohammed Dheyaa Marsool Marsool Mohamed Daoud Amir H Sohail Source Type: research
Effects of Recombinant Human Lecithin Cholesterol Acyltransferase on Lipoprotein Metabolism in Humans
CONCLUSIONS: Our results suggest that an acute increase in LCAT activity drives greater flux of cholesteryl ester through the reverse cholesterol transport pathway without significantly altering the clearance and production of the main HDL proteins and without affecting the metabolism of APOB100-lipoproteins. Long-term elevations of LCAT might, therefore, have beneficial effects on total body cholesterol balance and atherogenesis.PMID:38695168 | DOI:10.1161/ATVBAHA.123.320387 (Source: Atherosclerosis)
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Gissette Reyes-Soffer Anastasiya Matveyenko James Lignos Nelsa Matienzo Leinys S Santos Baez Antonio Hernandez-One Lau Yung Renu Nandakumar Sasha A Singh Masanori Aikawa Richard George Henry N Ginsberg Source Type: research
IL-1beta Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice
CONCLUSIONS: Taken together, IL-1β appears to be required for the maintenance of standard laboratory diet-induced reductions in plaque burden and increases in multiple indices of plaque stability.PMID:38695167 | DOI:10.1161/ATVBAHA.124.320800 (Source: Atherosclerosis)
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Santosh Karnewar Vaishnavi Karnewar Rebecca Deaton Laura S Shankman Ernest D Benavente Corey M Williams Xenia Bradley Gabriel F Alencar Gamze B Bulut Sara Kirmani Richard A Baylis Eli R Zunder Hester M den Ruijter Gerard Pasterkamp Gary K Owens Source Type: research
Genetic and inflammatory factors underlying gestational diabetes mellitus: a review
Front Endocrinol (Lausanne). 2024 Apr 17;15:1399694. doi: 10.3389/fendo.2024.1399694. eCollection 2024.ABSTRACTGestational diabetes mellitus (GDM) poses a significant global health concern, impacting both maternal and fetal well-being. Early detection and treatment are imperative to mitigate adverse outcomes during pregnancy. This review delves into the pivotal role of insulin function and the influence of genetic variants, including SLC30A8, CDKAL1, TCF7L2, IRS1, and GCK, in GDM development. These genetic variations affect beta-cell function and insulin activity in crucial tissues, such as muscle, disrupting glucose regul...
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Gyan Watson Ray Qiaoli Zeng Phidelia Kusi Hengli Zhang Taotao Shao Taili Yang Yue Wei Mianqin Li Xiaoqun Che Runmin Guo Source Type: research
