A speckle-tracking strain-based artificial neural network model to differentiate cardiomyopathy type.
Authors: Walsh JL, AlJaroudi WA, Lamaa N, Abou Hassan OK, Jalkh K, Elhajj IH, Sakr G, Isma'eel H Abstract Objectives. In heart failure, invasive angiography is often employed to differentiate ischaemic from non-ischaemic cardiomyopathy. We aim to examine the predictive value of echocardiographic strain features alone and in combination with other features to differentiate ischaemic from non-ischaemic cardiomyopathy, using artificial neural network (ANN) and logistic regression modelling. Design. We retrospectively identified 204 consecutive patients with an ejection fraction
Source: Scandinavian Cardiovascular Journal - October 20, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Acute type-A aortic dissection - a review.
Authors: Gudbjartsson T, Ahlsson A, Geirsson A, Gunn J, Hjortdal V, Jeppsson A, Mennander A, Zindovic I, Olsson C Abstract Objectives. Acute type-A aortic dissection (ATAAD) is still one of the most challenging diseases that cardiac surgeons encounter. Design. This review is based on the current literature and includes the results from the Nordic Consortium for Acute Type-A Aortic Dissection (NORCAAD) database. It covers different aspects of ATAAD and concentrates on the outcome of surgical repair. Results and conclusions. The diagnosis is occasionally delayed, and ATAAD is usually lethal if prompt repair is not pe...
Source: Scandinavian Cardiovascular Journal - September 24, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Association between atrial septal aneurysm and arrhythmias.
Conclusions. Certain types of arrhythmias such as APC, VPC, SVT and paroxysmal AF have been shown to be independently associated with the presence of ASA. PMID: 31544553 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - September 24, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Effect of exercise training on cardiac metabolism in rats with heart failure.
This study aimed to investigate the effects of exercise training at different intensities in rats with HF. Methods. Rats underwent myocardial infarction or sham operations and were divided into three subgroups: sedentary, moderate intensity, or high intensity. The impact of HF and 6 weeks of exercise training on energy metabolism was evaluated by 31P magnetic resonance spectroscopy and mitochondrial respirometry. The concentrations of PCr, ATP, and Pi were quantified by magnetic resonance spectroscopy. VO2max was measured by treadmill respirometry. Results. Exercise training increased VO2max in sham and HF. PCr/ATP ratio w...
Source: Scandinavian Cardiovascular Journal - September 11, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Acute effects of continuous positive airway pressure in patients with obstructive sleep apnea.
Conclusions. These results confirm the acute effects of one-night CPAP on lowering BP in OSA patients with morning hypertension. An unfavorable circadian BP pattern is the most important predictor. PMID: 31476878 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - September 4, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Intra-aortic balloon pump in acute chest pain and cardiogenic shock - a long-term follow-up.
Conclusions. We report the use of IABP in patients with acute chest pain admitted for angiography. Long-term survival is acceptable and discriminating factors were no revascularisation, out-of-hospital cardiac arrest and age. IABP was safe and feasible and the complication rate was low. PMID: 31476881 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - September 4, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Activated platelet aggregation is transiently impaired also by a reduced dose of protamine.
Authors: Olsson A, Alfredsson J, Thelander M, Svedjeholm R, Sanmartin Berglund J, Berg S Abstract Objectives: Protamine reduces platelet aggregation after cardiopulmonary bypass (CPB). We studied the inhibitory effect of a reduced protamine dose, the duration of impaired platelet function and the possible correlation to postoperative bleeding. Design: Platelet function was assessed by impedance aggregometry in 30 patients undergoing cardiac surgery with CPB at baseline, before protamine administration, after 70% and 100% of the calculated protamine dose, after 20 minutes and at arrival to the intensive care ...
Source: Scandinavian Cardiovascular Journal - September 4, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Osteocalcin and epicardial adipose tissue in obesity: new hints for epicardial adipose tissue-bone crosstalk.
Authors: Yaylali YT, Fidan-Yaylali G, Dedeoglu O, Senol H Abstract Objectives: Osteocalcin (OC) appears to be involved in the regulation of glucose and fat metabolism. We aimed to determine the association between OC and epicardial adipose tissue (EAT) in premenopausal obese women. Design: The study included 73 premenopausal obese women and 55 non-obese women. Echocardiographic examination was performed to measure EAT. Serum OC levels were measured by chemiluminescence immunoassay. Results: OC levels were significantly lower in obese women than controls (18.26 ± 5.27 vs. 22.53 ±&t...
Source: Scandinavian Cardiovascular Journal - August 29, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Deuterium oxide protects against myocardial injury induced by ischemia and reperfusion in rats.
Conclusions. D2O might have a beneficial effect of myocardium against ischemia, reperfusion and chemical hypoxia. PMID: 31455109 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - August 29, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Acute resveratrol supplementation in coronary artery disease: towards patient stratification.
CONCLUSION: Acute high dose supplementation with RV improved FMD in patients after CABG surgery but impaired FMD in patients who underwent PCI. The revascularization method-related differential effects of RV may be due to its direct effects on endothelial-dependent dilator responses. Our findings have important implications for personalized treatment and stratification of older CAD patients. PMID: 31429599 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - August 22, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

The long term risk of lead failure in patients with cardiovascular implantable electronic devices undergoing catheter ablation.
Conclusion. This study did not find any significant influence of CA on the long-term durability of CIED endocardial leads. Reported risk factors were consistent with general population of CIED patients. PMID: 31407601 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - August 15, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

National Survey of Current Practice and Opinions on Rehabilitation for Intermittent Claudication in the Danish Public Healthcare System.
Conclusion Vascular surgeons support referral and participation in IC rehabilitation to improve walking distance in patients with IC. Despite some hospitals and municipalities included patients with IC in rehabilitation nearly all services fail to meet current guideline as specific services tailored to patient with IC is almost non-existent in Denmark. Our findings call for action for services to comply with current recommendations of structured, systematic rehabilitation for patients with IC. PMID: 31394936 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - August 11, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Association of circulating osteocalcin with cardiovascular disease and intermediate cardiovascular phenotypes: systematic review and meta-analysis.
Authors: Seidu S, Kunutsor S, Khunti K Abstract Objectives: Circulating osteocalcin (OC), a marker which is central in bone mineralization, may be involved in the atherosclerotic process and influence the risk of developing cardiovascular disease (CVD). We conducted a systematic review and meta-analysis of published observational evidence, to assess and quantify the associations of circulating OC (total, undercarboxylated, and carboxylated OC) with cardiovascular outcomes (clinical CVD endpoints and intermediate cardiovascular phenotypes). Design: Relevant studies were identified in a literature search of MEDLINE, ...
Source: Scandinavian Cardiovascular Journal - August 11, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Relationship Between Invasive Hemodynamics and Liver Function in Advanced Heart Failure.
Authors: Vishram-Nielsen JK, Deis T, Balling L, Sabbah M, Boesgaard S, Rossing K, Wolsk E, Gustafsson F Abstract Objective: To examine how liver function (LF) relates to invasive hemodynamics cross-sectionally and longitudinally, in advanced heart failure (AHF) patients treated with maximally tolerated medical HF therapy. Design: A retrospective study of 309 consecutive AHF patients with a left ventricular ejection fraction
Source: Scandinavian Cardiovascular Journal - July 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

E/ รก ratio is closely related to pulmonary vein flow profile in patients with normal ejection fraction.
E/á ratio is closely related to pulmonary vein flow profile in patients with normal ejection fraction. Scand Cardiovasc J. 2019 Jul 22;:1-15 Authors: Johansson B, Lundin F, Tegeback R, Bojö L Abstract Objectives. To compare the ability of the E/á ratio and the recommended diastolic parameters in the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI), in predicting a dominant diastolic pulmonary vein flow in patients with normal ejection fraction. Design. We retrospectively evaluated the diastolic function according to the ASE/EAC...
Source: Scandinavian Cardiovascular Journal - July 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Successful recanalisation of coronary chronic total occlusions is not associated with improved cardiovascular survival compared with initial medical therapy.
Conclusion: In the treatment of patients with CTOs, successful PCI is not associated with improved long-term cardiovascular survival or reduced the risk of MACE compared with MT alone initially. PMID: 31315453 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - July 20, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

First and Recurrent Events after Percutaneous Coronary Intervention: Implications for Survival Analyses.
Authors: Vasudevan A, Choi JW, Feghali GA, Kluger AY, Lander SR, Tecson KM, Sathyamoorthy M, Schussler JM, Stoler RC, Vallabhan RC, Velasco CE, Yoon A, McCullough PA Abstract OBJECTIVE: Using composite endpoints and/or only first events in clinical research result in information loss and alternative statistical methods which incorporate recurrent event data exist. We compared information-loss under traditional analyses to alternative models. DESIGN: We conducted a retrospective analysis of patients who underwent percutaneous coronary intervention (Jan2010-Dec2014) and constructed Cox models for a composite endp...
Source: Scandinavian Cardiovascular Journal - July 20, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Short- and long-term Survival after Isolated Coronary Artery Bypass Grafting, the Impact of Gender and Age.
This study included 4044 consecutive patients who underwent isolated CABG at Oslo University Hospital, Ullevål, in Oslo, Norway in the time period from 01.01.2003 to 31.12.2015. Patient data was collected retrospectively from the quality register at the department. Information on survival status was obtained from the Norwegian National Registry. Life expectancy data for the general population was gained from Statistics Norway. RESULTS: Female patients were significantly older than male patients at the time of surgery (mean age 67.0 and 63.9 years respectively, p 
Source: Scandinavian Cardiovascular Journal - July 20, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Association of left atrial fibrosis with aortic excess pressure and white matter lesions.
Authors: Wykretowicz M, Katulska K, Zwanzig M, Krauze T, Piskorski J, Guzik P, Wykretowicz A Abstract OBJECTIVES: Left atrial fibrosis represents a substrate for atrial fibrillation (AF) and cardioembolic events. White matter hyperintensities (WMH) are commonly found on magnetic resonance imaging (MRI) and are regarded, at least partly as ischemic brain lesions. Aortic excess pressure (excessPTI) represents an extra work performed by the left ventricle and is a new risk metric associated with cardiovascular complications. The aim of our study was to assessed whether there is a correlation between the degree of LA f...
Source: Scandinavian Cardiovascular Journal - July 20, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Peripheral artery disease patients are poorly aware of their disease.
Authors: Builyte IU, Baltrunas T, Butkute E, Srinanthalogen R, Skrebunas A, Urbonavicius S, Rucinskas K Abstract OBJECTIVES: We hypothesized, that patients with peripheral arterial disease (PAD) are less aware of risk factors and possible outcomes of the disease compared to patients with coronary artery disease (CAD), which are similar. Hence, the aim of this study was to evaluate awareness of and attitudes towards PAD and CAD among patients, who are already diagnosed with either disease. DESIGN: A cross-sectional descriptive study was performed. Basic demographics, the presence and awareness of risk factors fo...
Source: Scandinavian Cardiovascular Journal - July 19, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

30-day mortality in frail patients undergoing cardiac surgery: The results of the Frailty In Cardiac Surgery (FICS) Copenhagen Study.
Conclusion: Frailty is common in patients undergoing cardiac surgery and carries increased risk of 30-day mortality and postoperative complications. The AUC indicates similar prediction of mortality for CAF score compared to the existing risk scores. Clinical trials registration ID: NCT02992587. PMID: 31304801 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - July 16, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Diagnosing Type 2 Myocardial Infarction in Clinical Routine. A Validation Study.
Conclusion: The SWEDEHEART registry agreed moderately with the gold standard in classifying patients with type 2 MI diagnosis. Thus, studies on patients with type 2 MI in the registry should be interpreted with caution. Since the prevalence of type 2 MI is substantially underestimated in SWEDEHEART, the registry should not be used to study the prevalence of type 2 MI. PMID: 31294615 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - July 13, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Mediastinitis in open heart surgery: a systematic review and meta-analysis of risk factors.
Conclusion: Evidence from this study showed the robustness of the risk factors in the pathogenesis of mediastinitis. Preventive measures can be implemented for reducing obesity, especially in lower latitude countries. Furthermore, it is mandatory to monitor perioperative hyperglycemias with continuous insulin infusion. Use of skeletonized BIMA carries higher risk of mediastinitis especially in female patients without evidence of beneficial effect on survival for the time being. PMID: 31290699 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - July 12, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Stable population-based incidence of acute type A and B aortic dissection.
Authors: Acosta S, Gottsäter A Abstract Background: Aortic dissection (AD) and abdominal aortic aneurysm (AAA) share the same risk factors. Whereas the incidence of AAA is falling, it is unclear whether population-based incidences of acute type A and B AD have changed. The aim of this study was to investigate incidences of AD subtypes over time. Methods: Citizens in the municipality of Malmö, Sweden, diagnosed with AD in 2000-2004 and 2014-2016 were identified through the in-patient, clinical, and forensic autopsy registers. Results: The overall and gender-specific incidences of acute type A and B AD were...
Source: Scandinavian Cardiovascular Journal - July 12, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Atrial fibrillation and anticoagulation in patients with breast cancer.
CONCLUSIONS: Breast cancer was not associated with altered risk of thromboembolism or bleeding in patients with atrial fibrillation irrespective of treatment with anticoagulation. Our analyses suggest that atrial fibrillation diagnosed in patients with breast cancer should be considered as primary atrial fibrillation. PMID: 31251080 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Poor Long-term Outcomes after Carotid Endarterectomy: A Retrospective Analysis of Two Portuguese Centers.
Authors: Alves-Ferreira J, Rocha-Neves J, Dias-Neto M, F Braga S Abstract Objetives: Carotid endarterectomy (CEA) is an established treatment for carotid stenosis (CS). However, this procedure is not risk-free and it is insufficient to control disseminated atherosclerosis. Our aim was to determine long-term cardiovascular (CV) morbidity and mortality after CEA and identify associated risk predictors. DESIGN: Consecutive cohorts of CEAs performed between 2010-2018 in two Portuguese hospitals were retrospectively analysed. The major end-points were acute myocardial infarction (AMI), stroke, all-cause death and ma...
Source: Scandinavian Cardiovascular Journal - June 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

A Post hoc analysis on rhythm and high intensity interval training in cardiac resynchronization therapy.
Conclusions. Patients in AF or SR undergoing CRT demonstrated distinct benefits from device implantation and from HIIT as an adjunctive therapeutic strategy. This suggests that both mainstay and adjunctive therapeutics may need to be managed differently in patients in AF and SR. PMID: 31221002 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain - the WESTCOR study: Study design.
Conclusion: The WESTCOR study will provide new diagnostic algorithms for early inclusion and exclusion of NSTE-ACS and insights in the associations between cardiovascular biomarkers, CT-angiographic findings and short and long-term clinical outcomes. PMID: 31216908 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 22, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Cardiorespiratory fitness is not associated with risk of venous thromboembolism: a cohort study.
Conclusions. In a middle-aged Caucasian male population, CRF was not associated with future risk of VTE. Further studies in women and other age-groups are required to confirm and to generalize these findings. PMID: 31180252 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 12, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Remote Ischaemic Preconditioning May Prolong Permissible Period of Hypothermic Circulatory Arrest in a porcine model.
Conclusions. RIPC tends to suppress cerebral metabolism during cooling with cardiopulmonary bypass and may prolong estimated permissible period of HCA. PMID: 31169413 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 8, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure.
Conclusions. A 12-week AIT intervention, although improving exercise capacity and endothelial function, did not attenuate serum inflammatory biomarkers in stable ischemic HF patients with an ICD on optimal medical therapy. PMID: 31169417 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 8, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Phase of Care Mortality Analysis and Failure to Rescue in a Norwegian Cardiothoracic Unit.
Conclusions: POCMA- and FTR-analyses can be carried out in clinical data which is well documented. The operating surgeon is in many cases not responsible for operative mortality, very few die due to FTR, but most patients die due to a multifactorial etiology. PMID: 31169422 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - June 8, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Exercise-induced ST depression in an asymptomatic population without coronary artery disease.
Authors: Carlén A, Gustafsson M, Åström Aneq M, Nylander E Abstract Objectives Exercise electrocardiogram (ExECG) in low risk populations frequently generates false positive ST depression. We aimed to characterize factors that are associated with exercise-induced ST depression in asymptomatic men without coronary artery disease. Design Cycle ergometer exercise tests from 509 male firefighters without imaging proof of significant coronary artery disease were analysed. Analysed test data included heart rate at rest before exercise, and workload, blood pressure, heart rate, ST depression and ST segme...
Source: Scandinavian Cardiovascular Journal - June 1, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Effect of long-term remote ischemic conditioning on inflammation and cardiac remodeling.
Conclusion: Our findings suggest that long-term RIC treatment has mild anti-inflammatory effects in patients with compensated CIHF and anti-remodeling effects in those with increased NT-proBNP levels. This should be further investigated in a randomized sham-controlled trial. PMID: 31117835 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 24, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Arterial hypertension and diastolic blood pressure associate with aortic stenosis.
CONCLUSION: Arterial hypertension and elevated diastolic blood pressure are associated with a risk for AS requiring surgery in subjects below 60 years of age. Strict blood pressure control in this group is strongly advocated to avoid other cardiovascular diseases correlated to hypertension. If hypertension and elevated diastolic blood pressure are risk factors for developing AS requiring surgery need further investigations. Notably, elevated fasting glucose levels were related to AS requiring surgery in older adults without concomitant CAD. PMID: 31109205 [PubMed - in process] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Aspirin plus Clopidogrel versus Aspirin Mono-Therapy for Ischemic Stroke: A Meta-Analysis.
Authors: Ye MB, Chen YL, Wang Q, An J, Ye F, Jing P Abstract OBJECTIVES: Stroke is a common condition after a transient ischemic attack (TIA) or minor ischemic stroke (IS). Adding clopidogrel to aspirin may yield more beneficial outcomes than aspirin mono-therapy; meanwhile, the risk of bleeding in the acute phase remains poorly understood. Therefore, there is increasing emphasis on the risks and benefits of clopidogrel with aspirin compared with aspirin mono-therapy in an effort to treat TIA/IS. DESIGN: We searched several electronic databases, including PubMed, Cochrane, and Embase, to identify eligible rando...
Source: Scandinavian Cardiovascular Journal - May 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Serum nitric oxide metabolites and hard clinical endpoints: Findings of a population-based prospective study.
CONCLUSION: Serum NOx level may be predictor of CVD mortality and death, in general populations. PMID: 31081695 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 14, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Correction.
Authors: PMID: 31072210 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - May 12, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Echocardiographic assessment at rest and during stress in patients with intermittent claudication.
Authors: Nordanstig J, Bech-Hanssen O, Skoog P, Jivegård L Abstract OBJECTIVE: Skeletal muscle perfusion during walking relies on complex interactions between cardiac activity and vascular control mechanisms, why cardiac dysfunction may contribute to intermittent claudication (IC) symptoms. The study aims were to describe cardiac function at rest and during stress in consecutive IC patients, to explore the relations between cardiac function parameters and treadmill performance, and to test the hypothesis that clinically silent myocardial ischemia during stress may contribute to IC limb symptomatology. DES...
Source: Scandinavian Cardiovascular Journal - May 9, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Statin-associated muscle symptoms in coronary patients - design of a randomized study.
Conclusions The study provides new knowledge on SAMS in coronary patients and may contribute to more personalized statin treatment and monitoring, fewer side-effects and consequently improved adherence and lipid management in future practice. PMID: 31030568 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - April 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Female Sex as a Risk Factor in Minimally Invasive Direct Coronary Artery Bypass Grafting.
Authors: Gofus J, Vobornik M, Sorm Z, Dergel M, Karalko M, Harrer J, Pojar M Abstract OBJECTIVES: Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. DESIGN: We retrospectively analysed the in-hospital data of all patients (n = 384) undergoing MIDC...
Source: Scandinavian Cardiovascular Journal - April 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Meta-analysis of Vitamin D Supplementation in the Treatment of Chronic Heart Failure.
Authors: Wang T, Liu Z, Fu J, Min Z Abstract OBJECTIVES: We performed a meta-analysis to determine whether vitamin D supplementation is beneficial in patients with chronic heart failure (CHF). DESIGN: Meta-analysis of randomised controlled trials. RESULTS: Vitamin D supplementation in patients with CHF improved health-related quality of life and C-reactive protein levels [weighted mean difference (WMD): 6.75, 95% confidence interval (CI): 2.87 to 10.64, P 
Source: Scandinavian Cardiovascular Journal - April 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Outcome after catheter ablation for left atrial flutter.
Authors: Giehm-Reese M, Lukac P, Kristiansen SB, Jensen HK, Gerdes C, Kristensen J, Nielsen JM, Kronborg MB, Nielsen JC Abstract Objectives Left atrial flutter has been reported in up to 10% of patients following pulmonary vein isolation or cardiac surgery. Left atrial flutter is typically highly symptomatic, responds poorly to medical antiarrhythmic treatment, and is often treated by catheter ablation. We aimed to investigate midterm freedom from recurrent arrhythmia after catheter ablation for left atrial flutter. Design In the National Danish Ablation Registry, we identified consecutive patients, who had undergo...
Source: Scandinavian Cardiovascular Journal - April 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Lipoprotein(a) is not associated with venous thromboembolism risk.
CONCLUSIONS: Primary analysis as well as pooled evidence from previous studies suggest circulating Lp(a) is not prospectively associated with future VTE risk, indicating that evidence of associations demonstrated in case-control designs may be driven by biases such as selection bias. PMID: 31032650 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - April 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Repair of Tricuspid Valve with Pulmonary Valve Replacement in Repaired Tetralogy of Fallot.
Authors: Kim TJ, Song J, Kim YS, Huh J, Kang IS, Yang JH, Jun TG Abstract OBJECTIVES: We aimed to investigate the outcome of tricuspid valve repair (TVR) performed concomitantly with pulmonary valve replacement in repaired tetralogy of Fallot (TOF) patients. DESIGN: This retrospective study included all patients who underwent pulmonary vale replacement from 2000 to 2016 after TOF correction. TVR patient data were compared to those of patients who underwent pulmonary vale replacement alone. RESULTS: Thirty-eight patients were enrolled. The degree of tricuspid regurgitation was significantly decreased after o...
Source: Scandinavian Cardiovascular Journal - April 26, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Risk scores and surgery for infective endocarditis: in search of a good predictive score.
CONCLUSIONS: Five of eight scores that were evaluated in this study showed satisfactory performance in predicting in-hospital mortality following surgery for IE. The ANCLA score should be preferred. PMID: 31007096 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - April 23, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Prognostic Impact of Recurrences in Patients with Electrical Storm.
CONCLUSION: At long-term follow-up of 2.5 years, ES-R was associated with numerically higher long-term all-cause mortality and with significantly increasing rates of re-hospitalization due to acute heart failure. LVEF ≤35% was associated with increased risk of ES-R. PMID: 30958708 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - April 10, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Twenty-Year Results of Surgical Pulmonary Thromboembolectomy in Acute Pulmonary Embolism.
CONCLUSION: Pulmonary embolectomy can be performed in high-risk patients with massive pulmonary embolism with acceptable clinical outcome and good long-term survival. PMID: 30919668 [PubMed - as supplied by publisher] (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - March 30, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

High on-Clopidogrel Platelet Reactivity and Chronic Kidney Disease: A meta-analysis of Literature Studies.
Authors: Wu Y, Song Y, Pan Y, Gong Y, Zhou Y Abstract BACKGROUND: The efficacy of clopidogrel is often attenuated in the setting of renal impairment. High on-treatment platelet reactivity (HPR) is an independent correlate of adverse event. Here we performed a quantitative evaluation of the prevalence and impact of HPR in patients with chronic kidney disease (CKD). METHODS: We systematically searched PubMed, EMBASE and the Cochrane Library from their inception to 1 March 2018 for cohort studies assessing the risk ratio (RR) of prevalence of HPR in CKD versus non-CKD patients and association of cardiovascular out...
Source: Scandinavian Cardiovascular Journal - March 28, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Long-term outcome of catheter ablation in post-infarction recurrent ventricular tachycardia.
We present retrospective analysis of long-term outcome after single and repeat VT ablation procedures in patients with ischemic heart disease. DESIGN: Patients with recurrent VT post infarction who underwent catheter ablation between 2006 and 2017 in Isala Heart Centre were retrospectively analyzed. Univariate and multivariate analysis were used to identify predictors of arrhythmia recurrence post ablation. Patients were allocated to subgroups based on LVEF: severe (
Source: Scandinavian Cardiovascular Journal - March 28, 2019 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research