Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Factors Influencing Mortality Following Liver Transplant in Acute Liver Failure: A Single Center Experience.
In this study, our aim was to evaluate and determine the factors related to mortality in patients who received liver transplants in accordance with King's College criteria for acute liver failure in order to prevent futile operations. MATERIALS AND METHODS: Our study included 65 adult patients with acute liver failure who received liver transplant according to King's College criteria. Factors related to mortality, including demographic and operative data, causes of acute liver failure, severity of encephalopathy, and laboratory data, were retrospectively analyzed. Patients who received living-donor liver grafts had do...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 9, 2019 Category: Transplant Surgery Authors: Sahin TT, Sarici KB, Kilci B, Koc C, Otan E, Karakas S, Kutluturk K, Aydin C, Kayaalp C, Yilmaz S Tags: Exp Clin Transplant Source Type: research

Liver Transplant in Patients With Portal Vein Thrombosis: The Experience of 55 Patients.
CONCLUSIONS: In contrast to early-grade portal vein thrombosis, complete portal vein thrombosis still provides a treatment challenge with high risk of morbidity and poor early outcomes in liver transplant recipients. PMID: 31066351 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 8, 2019 Category: Transplant Surgery Authors: Ozer A, Aktas H, Yilmaz TU, Guner Can M, Gurluler E, Yildiz I, Emiroglu R Tags: Exp Clin Transplant Source Type: research

Defining a Liver Transplant Benefit Threshold for the Model for End-Stage Liver Disease-Sodium Score.
Abstract OBJECTIVES: The benefits of transplant are shown as the difference in survival posttransplant versus that shown if the patient had remained on the wait list. Serum sodium was added to improve prediction. We sought to revisit the question of which Model for End-Stage Liver Disease-Sodium score threshold corresponded to a predicted benefit of liver transplant. MATERIALS AND METHODS: Data on adult patients (≥ 18 years old) were obtained from the United Network for Organ Sharing registry (date range of June 18, 2013 to December 2016). Exclusion criteria were individuals listed for multiple organs or l...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Beal EW, Akateh C, Tumin D, Bagante F, Black SM, Washburn K, Azouley D, Pawlik TM Tags: Exp Clin Transplant Source Type: research

Fever of Unknown Origin in a Renal Transplant Recipient: Lactate Dehydrogenase as an Important Clue to Diagnosis.
We report a case of a 23-year-old male patient who presented with fever of unknown origin, cytopenias, organomegaly, and allograft dysfunction 4 months after renal transplant with father as donor. Bone marrow examination showed intracellular budding yeast cells, which was confirmed as histoplasmosis by culture of bone marrow biopsy sample. The patient was treated with intravenous liposomal amphotericin and responded well. PMID: 31050612 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Sethi J, Gupta KL, Mohanty T, Gupta S, Ahluwalia J, Kohli HS Tags: Exp Clin Transplant Source Type: research

Vaccination Status in Pediatric Solid-Organ Transplant Recipients and Their Household Members.
CONCLUSIONS: We found that most pediatric solid-organ transplant recipients to be appropriately vaccinated. However, vaccination status in household members, especially in parents, was disappointing. PMID: 31050613 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Cortina G, Ojinaga V, Zlamy M, Giner T, Riedl M, Rauchenzauner M, Entenmann A, Müller T Tags: Exp Clin Transplant Source Type: research

Alemtuzumab Induction Is Associated With Equalization of Graft Outcomes Between Elderly and Nonelderly Kidney Transplant Recipients: A Single-Center Report.
Abstract OBJECTIVES: Alemtuzumab (monoclonal anti-CD52 antibody) provides profound lymphocyte depletion and offers numerous advantages as an induction agent. Elderly recipients (> 65 years old) traditionally have inferior posttransplant outcomes versus younger recipients. We investigated short-term and long-term patient and graft survival rates following alemtuzumab induction in elderly recipients. MATERIALS AND METHODS: This retrospective analysis, which included 676 renal allograft transplant recipients with alemtuzumab induction, was conducted at the University of Toledo Medical Center between March 200...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: DeLeonibus A, Mitro G, Brooks J, Rees M, Ortiz J Tags: Exp Clin Transplant Source Type: research

Adrenalectomy for Bilateral Metachronous Adrenal Recurrence of Hepatocellular Carcinoma After Liver Transplant: A Case Report.
We describe a case of a 56-year-old man who underwent liver transplant for hepatocellular carcinoma in a cirrhotic liver. Two years after liver tranplant, regular follow-up revealed metastatic disease in the left adrenal gland. Preoperative imaging showed no other metastasis, and he underwent an uneventful left adrenalectomy. A year after surgery, he presented with right flank pain and tenderness. Imaging showed hemorrhage and tumor involvement of the right adrenal gland, and he underwent right adrenalectomy. Two years after surgery, he is alive and well with no signs of disease recurrence. Apparently, in the absence of in...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Mikulic D, Stironja I, Jadrijevic S, Skrtic A, Mrzljak A, Filipec Kanizaj T, Kocman B Tags: Exp Clin Transplant Source Type: research

Ultrasonography-Based Dynamic Assessment on an Adult for Postoperative Effects of Double Kidney Transplant From a 6-Month-Old Donor.
Abstract To allow improved quality of life, renal transplant has been regarded as the best therapeutic option for patients with end-stage renal disease. However, due to shortages of renal sources, annually, only a few patients with renal failure can receive transplants, with most patients requiring hemodialysis to maintain their life. With increasing imbalance of demands and supplies for donor organs, infant organ donors have become an important part of domestic and foreign transplant sources. It is of great importance to guarantee successful kidney transplant outcomes. Examination of the size and blood perfusion ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Zhu D, Zheng Q, Wu M Tags: Exp Clin Transplant Source Type: research

Conversion From Twice-Daily to Once-Daily Tacrolimus Among Egyptian Living-Donor Kidney Allograft Recipients: A Single-Center Experience.
CONCLUSIONS: Conversion from conventional tacrolimus (twice daily) to once-daily tacrolimus may be a valuable option with comparable patient and graft survival and may lead to improved adherence that may be reflective of better long-term results. It should be considered for de novo immunosuppression among living-donor renal allotransplant recipients. PMID: 31050617 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Bakr MA, Nagib AM, Abbas MH, Donia AF Tags: Exp Clin Transplant Source Type: research

Natural Killer Cells Exhibit an Activated Phenotype in Peripheral Blood Mononuclear Cells of Renal Allograft Rejection Recipients: A Preliminary Study.
CONCLUSIONS: These findings suggest that the increase in natural killer cell cytotoxicity is correlated with rejection in kidney transplant recipients and might be considered as a predictive marker in prevalence of graft rejection. PMID: 31050618 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Talebzadeh Bonakdar A, Mohammadi MM, Namdar A, Ahmadpoor P, Jafari D, Yekaninejad MS, Amirzargar AA Tags: Exp Clin Transplant Source Type: research

Feasibility of Boari Bladder Flap Procedure in Patients With Heterotrophic Renal Transplant.
CONCLUSIONS: The Boari bladder flap procedure can be a safe and relevant choice in the management of challenging complications after heterotrophic (either allogeneic or autotransplant) renal transplant, allowing minimally invasive urologic surgery, no need for use of bowel segments, and no potential risk for the contralateral kidney. PMID: 31050619 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Tonyali S, Haberal HB, Bilen CY, Aki FT Tags: Exp Clin Transplant Source Type: research

Single-Center Retrospective Study of Clinical and Laboratory Features That Predict Survival of Patients With Budd-Chiari Syndrome After Liver Transplant.
Abstract OBJECTIVES: Budd-Chiari syndrome is a rare but critical condition that can progress to liver failure and death. For severe cases, orthotopic liver transplant remains the only curative option. The present study aimed to identify predictive parameters to assess outcomes of liver transplant. MATERIALS AND METHODS: Medical records of 33 individuals with Budd-Chiari syndrome who received orthotopic liver transplant were retrospectively assessed. Twenty-seven eligible patients were identified and grouped by outcome (survived/deceased) after transplant for Budd-Chiari syndrome. Demographic, clinical, and se...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Jeschke B, Gottlieb A, Sowa JP, Jeschke S, Treckmann JW, Gerken G, Canbay A Tags: Exp Clin Transplant Source Type: research

Effect of Propranolol Treatment on the Incidence of Hepatocellular Carcinoma in Patients Waiting for Liver Transplant With Cirrhosis: A Retrospective, Surveillance Study in a Tertiary Center.
In this study, our aim was to determine the effects of propranolol treatment on the incidence of hepatocellular carcinoma in cirrhotic patients waiting for liver transplant. MATERIALS AND METHODS: We retrospectively reviewed the data of patients waiting for liver transplant with cirrhosis due to various causes registered at the Hepatocellular Carcinoma Surveillance Program between June 2011 and December 2017 in our center. These data were compared between patients using propranolol and those not using propranolol. RESULTS: Of the 231 patients, 135 (58.4%) were male and 96 (41.6%) were female. The mean age was 58....
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - May 2, 2019 Category: Transplant Surgery Authors: Suna N, Mohammadi MM, Özer Etik D, Öcal S, Selçuk H Tags: Exp Clin Transplant Source Type: research

Vascular Anomalies of the Extrahepatic Artery as a Predictable Risk Factor for Complications After Liver Transplant.
CONCLUSIONS: Unexpectedly, recipients with variations of the hepatic artery and grafts with an abnormal arterial supply did not show higher rates of com-plications or mortality. Only vascular reconstruction of the graft before transplant raised the mortality of recipients. PMID: 30995892 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Teegen EM, Globke B, Denecke T, Pascher A, Öllinger R, Pratschke J, Chopra SS Tags: Exp Clin Transplant Source Type: research

Prevalence and Risk Factors of BK Viremia and Clinical Impact of BK Virus Surveillance on Outcomes in Kidney Transplant Recipients: A Single-Center Cross-Sectional Study.
Abstract OBJECTIVES: BK virus is a polyomavirus that can cause nephropathy and graft loss after kidney transplant. The aim of our study was to screen the BK viremia prevalence, to understand the value of the inter-vention for BK virus nephropathy, and to determine the risk factors associated with BK viremia after kidney transplant in our center. MATERIALS AND METHODS: Our retrospective cross-sectional study included 91 adult kidney transplant recipients who were seen between 2015 and 2017 and who had follow-up from 1 month to over 2 years. BK viremia was evaluated by use of plasma quantitative polymerase chai...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Ji J, Feng S, Jiang Y, Wang W, Zhang X Tags: Exp Clin Transplant Source Type: research

Outcome of Liver Transplant Patients With Intraoperative-Detected Portal Vein Thrombosis: A Retrospective Cohort Study in Shiraz, Iran.
CONCLUSIONS: One of every 9 liver transplant patients had intraoperative-detected portal vein thrombosis. Hazard of death was 2.9, and death occurred far earlier in patients with this complication. Improvements in diabetes mellitus care, prothrombin time, Model for End-Stage Liver Disease score, and body mass index may improve outcomes of these patients. PMID: 30995894 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Bagheri Lankarani K, Honarvar B, Seif MA, Anushiravani A, Nikeghbalian S, Motazedian N, Janghorban P, Foroutanifard E, Akbari M, Malekhosseini SA Tags: Exp Clin Transplant Source Type: research

Half Saline-Bicarbonate Solution as Intraoperative Fluid Replacement Therapy Leads to Less Acidosis and Better Early Renal Function During Deceased-Donor Transplant.
CONCLUSIONS: The use of half saline-bicarbonate was associated with better early graft function compared with normal saline in the first 7 days after transplant. PMID: 30995895 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Pourfakhr P, Shafiei M, Etezadi F, Khajavi MR, Moharari RS Tags: Exp Clin Transplant Source Type: research

Relationship Between Venous Drainage Patterns and Regeneration of Segments 5 and 8 in Right Lobe Grafts in Adult Living-Donor Liver Transplant Recipients.
In this study, we aimed to investigate the precise outflow pattern of segments 5 and 8 between the right hepatic vein and middle hepatic vein and the respective regeneration rates after living-donor liver transplant with right lobe graft, as available data on these relevant topics are scarce. MATERIALS AND METHODS: We conducted a retrospective analysis of computed tomography scans with 3-dimensional simulation, vessel reconstruction, and volume measurement of 38 right lobe grafts without middle hepatic vein. Follow-up time was 3 months after living-donor liver transplant. RESULTS: In donors, segments 5 and 8 meas...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Pravisani R, Soyama A, Takatsuki M, Hidaka M, Adachi T, Ono S, Hara T, Hamada T, Kanetaka K, Eguchi S Tags: Exp Clin Transplant Source Type: research

Evaluation of Whether Kidney Paired Donations Improve Overall Transplant Center Performance.
CONCLUSIONS: Kidney paired donation transplant does not appear to affect transplant center performance. This may be due to the small volume of these transplants currently performed by centers, thereby limiting overall growth in the number of transplants and new registrations. PMID: 30995897 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Wenig AJ, Koizumi N, Nayebpour M, Ortiz J Tags: Exp Clin Transplant Source Type: research

HLA Class I Expression Changes in Different Types of Cultured Parathyroid Cells.
CONCLUSIONS: HLA class I expression levels of para-thyroid hyperplasia and adenoma tissue were not found to be similar. Parathyroid hyperplasia tissue is the donor tissue for the treatment of permanent hypoparathyroidism. Therefore, expression patterns of HLA class I are directly relevant to the transplant process. In particular, the HLA region is highly polymorphic, and, as a consequence of this, heterogeneous correlations among HLA-A, HLA-B, and HLA-C expression patterns of parathyroid tissue should be evaluated in detail before transplant for future studies. PMID: 30995898 [PubMed - as supplied by publisher] (Sourc...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 17, 2019 Category: Transplant Surgery Authors: Goncu B, Yucesan E, Aysan E, Kandas NO Tags: Exp Clin Transplant Source Type: research

Identifying Factors That Affect Patient Survival After Orthotopic Liver Transplant Using Machine-Learning Techniques.
CONCLUSIONS: Data mining analyses can help identify effective features of patient survival after liver transplant and build models with equal or higher performance than Cox regression. The order of influential factors identified with the machine-learning model was close to clinical experiments. PMID: 30968757 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Kazemi A, Kazemi K, Sami A, Sharifian R Tags: Exp Clin Transplant Source Type: research

Atypical Presentation of Aspergillus Mediastinitis Infection in a Heart Transplant Patient: the Importance of Combined Medical and Surgical Treatment.
We present the case of a 50-year-old man who developed Aspergillus mediastinitis 1 year after heart transplant surgery. This case illustrates the diagnostic challenge of an atypical presentation of Aspergillus mediastinitis and the importance of multiple drainage procedures in refractory disease, combined with long-term antifungal therapy. PMID: 30968758 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Caron J, Conti M, Pietro R, Tessier M, Gervais P, Dubois-Sénéchal SM, Cinq-Mars A, Dubois M, Sénéchal M Tags: Exp Clin Transplant Source Type: research

Type of Organ Transplanted Impacts the Risk and Presentation of Cutaneous Squamous Cell Carcinoma in Transplant Recipients.
Abstract OBJECTIVES: Transplant immunosuppression increases the risk of cutaneous squamous cell carcinoma by 65- to 200-fold. Our objective was to investigate the impact of the type of organ transplanted on the risk and presentation of cutaneous squamous cell carcinoma. MATERIALS AND METHODS: The retrospective database of the Duke University Health System was queried to identify patients who underwent an organ transplant from 1996 to 2016. Data regarding transplant outcomes, cutaneous squamous cell carcinoma, immunosuppressive regimens, and survival were recorded. We used chi-square tests, analysis of varianc...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Puza CJ, Beasley GM, Barbas AS, Mosca PJ Tags: Exp Clin Transplant Source Type: research

Severe Respiratory Syncytial Virus Pneumonia in a Kidney Transplant Recipient With Desensitization: Case Report and Comprehensive Review of the Literature.
Abstract Herein, we report a rare case of severe respiratory syncytial virus pneumonia after kidney transplant in a 46-year-old woman. The patient was diagnosed with end-stage renal disease and underwent living-donor kidney transplant. Direct flow cytometry crossmatch testing yielded positive results, and desensitization treatment with rituximab, plasmapheresis, and im-munoglobulin was performed before transplant. There were no complications. Five days after discharge, the patient was readmitted with a 2-day history of fever and diagnosed with bilateral pneumonia. The patient was placed on mechanical ventilation a...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Lee ES, Kim KY, Jeong KH, Lim JH, Jung HY, Choi JY, Cho JH, Park SH, Kim YL, Kim CD Tags: Exp Clin Transplant Source Type: research

Late Plasma Cell Depletion After Thymoglobulin Induction in Kidney Transplant Recipients.
CONCLUSIONS: Rabbit antithymocyte globulin induction leads to a late reduction in the number of circulating plasma cells at 1 year after kidney transplant. This effect can contribute to down-regulation of the humoral alloantibody response. PMID: 30968761 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Irure J, Sango C, Segundo DS, Fernández-Fresnedo G, Ruiz JC, Benito-Hernández A, Asensio E, López-Hoyos M, Rodrigo E Tags: Exp Clin Transplant Source Type: research

Platelet-to-Lymphocyte Ratio as a Potential Indicator of Infection-Associated Emergency Visits of Renal Transplant Recipients.
CONCLUSIONS: For systemic inflammation, platelet-to-lymphocyte ratio can be used in conjunction with other biomarkers as an indicator of inflammation in renal transplant recipients who present with infection-associated causes to emergency departments. PMID: 30968762 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Muratoglu M, Kayipmaz AE, Kavalci C, Kirnap M, Moray G, Haberal M Tags: Exp Clin Transplant Source Type: research

Impact of the Inferior Right Hepatic Veins on Right Liver Lobe Regeneration in Living-Donor Liver Transplant: 3-Dimensional Computed Tomography Scan Analyses in Donors and Recipients.
CONCLUSIONS: The reconstruction policy for inferior right hepatic vein with caliber> 5 mm is effective but should be implemented with computed tomography scan simulation. Right lobe grafts with a dominant inferior right hepatic vein are at higher risk of impaired regeneration due to expected large volumes of hepatic venous congestion if the middle hepatic veins tributaries or the inferior right hepatic veins are not reconstructed and an increased rate of right hepatic vein complications. PMID: 30968763 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the M...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 9, 2019 Category: Transplant Surgery Authors: Pravisani R, Soyama A, Takatsuki M, Hidaka M, Adachi T, Ono S, Hara T, Hamada T, Eguchi S Tags: Exp Clin Transplant Source Type: research

Burden, Access, and Disparities in Kidney Disease.
Abstract PMID: 30945627 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 1, 2019 Category: Transplant Surgery Authors: Crews DC, Bello AK, Saadi G, World Kidney Day Steering Committee Tags: Exp Clin Transplant Source Type: research

Diabetic Nephropathy Following Posttransplant Diabetes Mellitus.
Abstract Diabetic nephropathy is one of the main long-term diabetic microangiopathies that can complicate type 1 and 2 and other secondary forms of diabetes mellitus, including posttransplant diabetes mellitus. Posttransplant diabetes mellitus was initially reported in the 1960s, with case reports of recurrent and de novo diabetic nephropathy after kidney transplant reported in the early 2000s, mostly as a result of same-risk and precipitating factors of diabetic nephropathy as in native kidneys. The disease may appear early in view of the hyperfiltration risk of being a single grafted kidney. Here, we discuss ris...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 1, 2019 Category: Transplant Surgery Authors: Nagib AM, Elsayed Matter Y, Gheith OA, Refaie AF, Othman NF, Al-Otaibi T Tags: Exp Clin Transplant Source Type: research

Acute Rejection Is a Strong Negative Predictor of Graft Survival in Living-Donor Pediatric Renal Transplant: 10-Year Follow-Up in a Single Mexican Center.
Abstract OBJECTIVES: Kidney transplant is the optimal treatment for children with end-stage renal disease. Multiple factors affect patient and graft survival. We assessed determinants of long-term patient/graft survival in our center by a retrospective review of pediatric living donor (
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 1, 2019 Category: Transplant Surgery Authors: Martinez-Mier G, Mendez-Lopez MT, Soto-Miranda E, Moreno-Ley PI, Budar-Fernandez LF, Rizo-Velazquez CG, Vega-Rojano L Tags: Exp Clin Transplant Source Type: research

Urothelial Carcinoma Detected by Ultrasonography in a Renal Transplant Recipient.
Abstract Urothelial cell carcinoma in renal transplant recipients has been rarely reported. Here, we report a case of high-grade papillary urothelial carcinoma in a renal transplant recipient who presented with hematuria. Sonographic evaluations (gray-scale ultrasonography, Doppler imaging, and strain sonoelastography) helped with diagnosis in our initial approach to the patient. Computed tomography was performed to confirm solid ureteral masses and staging of the disease. The patient, who underwent nephro-ureterectomy of the graft kidney, had that kidney for 6 years, 6 months. After surgery, the patient was sympt...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 1, 2019 Category: Transplant Surgery Authors: Altinbas NK, Gunertem G Tags: Exp Clin Transplant Source Type: research

Correlation and Prediction of Living-Donor Remaining Function by Using Predonation Computed Tomography-Based Volumetric Measurements: Role of Remaining Kidney Volume.
Abstract OBJECTIVES: Kidney volume in healthy living donors may serve as a surrogate marker of renal function. Here, we evaluated whether preserved kidney volume correlated with and could predict donor renal function at 2 years postdonation using the CKD-EPI estimated glomerular filtration rate equation. MATERIALS AND METHODS: Healthy living donors (n = 208) with computed tomography volume measurements were evaluated for renal function before and after donation. Preserved kidney volume was adjusted to body surface area. Demographic characteristics (including race/ethnicity and sex) and renal function variable...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Khalil A, Yaqub MS, Taber T, Powelson J, Goggins W, Sundaram CP, Diez A, Sharfuddin A Tags: Exp Clin Transplant Source Type: research

Autotransplantation of the Liver for Ex Vivo Resection of Intrahepatic Caval Leiomyosarcoma: A Case Report.
In conclusion, ex vivo resection of an intrahepatic caval leiomyosarcoma with inferior caval vein replacement by a deceased-donor caval graft and subsequent liver autotransplantation are technically demanding but provide a chance on prolonged survival. PMID: 30880647 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Buchholz BM, Pinter Carvalheiro da Silva Boteon A, Taniere P, Isaac JR, Gourevitch D, Muiesan P Tags: Exp Clin Transplant Source Type: research

Vascular Complications After Liver Transplantation.
CONCLUSIONS: Because vascular complications are the most severe complications after liver transplant, there must be close follow-up of vascular anastomoses, particularly early postoperatively, with radiologic methods. In cases of vascular complications, emergent treatment, including endovascular interventions, surgery, and retransplant, must be performed. PMID: 30880648 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Astarcıoglu I, Egeli T, Gulcu A, Ozbilgin M, Agalar C, Cesmeli EB, Kaya E, Karademir S, Unek T Tags: Exp Clin Transplant Source Type: research

Correlation and Prediction of Living-Donor Remaining Function by Using Predonation Computed Tomography-Based Volumetric Measurements: Role of Remaining Kidney Volume.
Abstract OBJECTIVES: Kidney volume in healthy living donors may serve as a surrogate marker of renal function. Here, we evaluated whether preserved kidney volume correlated with and could predict donor renal function at 2 years postdonation using the CKD-EPI estimated glomerular filtration rate equation. MATERIALS AND METHODS: Healthy living donors (n = 208) with computed tomography volume measurements were evaluated for renal function before and after donation. Preserved kidney volume was adjusted to body surface area. Demographic characteristics (including race/ethnicity and sex) and renal function variable...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Khalil A, Yaqub MS, Taber T, Powelson J, Goggins W, Sundaram CP, Diez A, Sharfuddin A Tags: Exp Clin Transplant Source Type: research

Early Postoperative Acute Kidney Injury Among Pediatric Liver Transplant Recipients.
Abstract OBJECTIVES: Acute kidney injury after pediatric liver transplant is associated with increased morbidity and mortality. Here, we evaluated children with acute kidney injury early posttransplant using KDIGO criteria to determine incidence, risk factors, and clinical outcomes. MATERIALS AND METHODS: In this retrospective cohort study, medical records of all patients
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Sahinturk H, Ozdemirkan A, Zeyneloglu P, Gedik E, Pirat A, Haberal M Tags: Exp Clin Transplant Source Type: research

Portal Vein Flow by Doppler Ultrasonography and Liver Volume by Computed Tomography in Living Donor Candidates: Correlation with Indocyanine Green Test.
Abstract OBJECTIVES: Our goal was to investigate the correlation between indocyanine green test results and imaging parameters in living liver donor candidates. MATERIALS AND METHODS: Our study included 219 healthy donor candidates who were evaluated with Doppler ultrasonography (portal vein time average flow), computed tomography (liver volume), liver biopsy (fat fraction), and indocyanine green retention rate at 15 minutes. RESULTS: Portal vein time average flow (r= -0.375), fat-free liver volume/body weight ratio (r = -0.239), and portal vein time average flow × fat-free liver volume/body weight...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Lee S, Kim KW, Lee J, Park T, Song GW, Lee SG Tags: Exp Clin Transplant Source Type: research

Characterizing the B-Cell and Humoral Response in Tertiary Lymphoid Organs in Kidney Allografts.
CONCLUSIONS: B cells within tertiary lymphoid organs are functional and contribute to the humoral arm of the alloresponse. However, tertiary lymphoid organs are not necessarily associated with graft rejection, suggesting that protective mechanisms are at play. PMID: 30880652 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: Nowocin AK, Meader L, Brown K, Elgueta R, Wong W Tags: Exp Clin Transplant Source Type: research

Rituximab as a Preemptive Treatment to Prevent Recurrence of Primary Focal Segmental Glomerulosclerosis: A Novel Approach.
CONCLUSIONS: Rituximab at day 0 posttransplant may be used safely to prevent focal segmental glomeru-losclerosis recurrence in the graft in the early posttransplant period. However, longer follow-up studies with larger series are needed. PMID: 30880653 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 14, 2019 Category: Transplant Surgery Authors: El Khashab S, El Khashab O, El Ghoneimy M, AbdelRassoul MA Tags: Exp Clin Transplant Source Type: research

Evaluation of Underlying Liver Disease and Its Severity in Children Referred for Liver Transplant: a Single-Center Report From Nemazee Hospital of Shiraz.
Abstract OBJECTIVES: Liver transplant has been used as a curative approach for children with end-stage liver diseases. Here, we describe the underlying causes for pediatric liver transplant performed at the Shiraz Organ Transplantation Center, Nemazee Hospital, Shiraz, Iran. MATERIALS AND METHODS: In this cross-sectional des-criptive study, children
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 5, 2019 Category: Transplant Surgery Authors: Dehghani SM, Shahramian I, Bazi A, Mohammadi Mofrad M, Mardani S Tags: Exp Clin Transplant Source Type: research

United Network for Organ Sharing Rule Changes and Their Effects on Kidney and Liver Transplant Outcomes.
CONCLUSIONS: Liver transplants showed a higher risk of lower viability with travel, and the Share 35 rule did not appear to change this result. Kidney transplant outcomes appear to have improved after the kidney allocation system change. Potential strategies for minimizing cold ischemia time and improving outcomes include more free-standing organ recovery centers in centralized locations. PMID: 30836905 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 5, 2019 Category: Transplant Surgery Authors: Tolkacz M, Friedman JM, Koizumi N, Tang L, Ortiz J Tags: Exp Clin Transplant Source Type: research

Percutaneous Drainage of a Splenic Abscess via Laparoscopic Trocar in a Kidney Transplant Patient.
Abstract Spleen abscess is a life-threatening disease. Treatment can be done by medical, radiological, or surgical methods. Here, we offer an innovative method of laparoscopic trocar-assisted percutaneous abscess drainage in the treatment of splenic abscess. Our patient, a 48-year-old male who had a kidney transplant 3 years previously, was admitted due to abdominal pain and fever. A-25-cm splenic abscess was detected, and ultrasonography-guided percu-taneous catheter 10F drainage was attempted. However, this attempt was not successful due to the high viscosity of the abscess content. Under general anesthesia, we ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 5, 2019 Category: Transplant Surgery Authors: Aktas A, Kayaalp C, Gundogan E, Gunes O, Pıskın T Tags: Exp Clin Transplant Source Type: research

Alemtuzumab as a Successful Antirejection Therapy: Experience in a Pediatric Renal Transplant Patient.
;akar N, Yalçınkaya F Abstract Alemtuzumab is a monoclonal antibody against CD52 that is being increasingly used in renal transplantation as a lymphocyte-depleting agent. Data on alemtuzumab use in resistant rejection episodes are scarce, especially in children. Here, we present a 14-year-old renal transplant patient with acute cellular and humoral rejection who was treated with pulse steroids, plasmapheresis, and intravenous immunoglobulin with no success. He had 2 previous rejection episodes that were treated with antithymocyte globulin. In the third episode, alemtuzumab was given as a rescue therapy, an...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2019 Category: Transplant Surgery Authors: Kurt-Şükür ED, Birsin Özçakar Z, Keven K, Çakar N, Yalçınkaya F Tags: Exp Clin Transplant Source Type: research

Perioperative-, Recipient-, and Donor-Related Factors Affecting Delayed Graft Function in Kidney Transplantation.
CONCLUSIONS: Efforts should be focused on limiting cold ischemia time and associated injury to reduce occurrence of delayed graft function and consequently improve long-term graft survival in kidney transplant recipients. Optimization of posttransplant renal function with the help of new technologies, such as pulsatile perfusion, could be crucial for minimization of cold ischemia time. PMID: 30806201 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2019 Category: Transplant Surgery Authors: Aceto P, Perilli V, Luca E, Salerno MP, Punzo G, Ceaichisciuc I, Cataldo A, Lai C, Citterio F, Sollazzi L Tags: Exp Clin Transplant Source Type: research

Retransplant Outcomes Compared With First Kidney Transplants: Important Observations Not Reported in the Scientific Registry of Transplant Recipients Annual Report.
CONCLUSIONS: It would be extremely valuable if the Scientific Registry of Transplant Recipients could present stratified analyses that would account for a host of factors, including organ sequence, which tend to vary by center. The presentation of risk-adjusted outcomes in the annual Registry report could include a more comprehensive assessment of program performance. Such information would be extremely useful for transplant centers, patients, and their support networks, organ procurement organizations, and other transplant stakeholders. PMID: 30806202 [PubMed - as supplied by publisher] (Source: Experimental and Clin...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2019 Category: Transplant Surgery Authors: Serrano OK, Matas AJ Tags: Exp Clin Transplant Source Type: research

Level of Daily Life Activities and Learning Needs in Renal Transplant Patients.
CONCLUSIONS: Our study patients reported that their overall daily life activities and quality of life, given the holistic approach to treatment and care, were good. However, when we examined each activity separately, our findings showed that patients lacked information regarding how to cope with stress, emotions, and the effects of renal transplant on their life. PMID: 30806203 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2019 Category: Transplant Surgery Authors: Pehlivan S, Vatansever N, Arslan İ, Yildiz A, Ersoy A Tags: Exp Clin Transplant Source Type: research

Repeat Kidney Transplant in a Patient With a Double Inferior Vena Cava and Difficult Venous Access: A Case Report.
We present a case of a 29-year-old man with end-stage renal disease who was scheduled for repeat kidney renal transplant from a living related donor. His transplant posed many challenges to the transplant team. These included (1) difficult access for dialysis, which required transhepatic insertion of a dialysis catheter, (2) anomalous inferior vena cava anatomy with a double inferior vena cava, (3) a blocked right inferior vena cava, and (4) a small blocked bridging vein connecting the right inferior vena cava to an additional left inferior vena cava. A stent was inserted into the bridging vein to allow venous drainage fro...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2019 Category: Transplant Surgery Authors: Stern S, Merhav H, Abu Gazala S, Bloom AI, Khoury T, Mor-Yosef-Levi I, Elhalel-Dranitzky M, Tzukert K, Khalaileh A Tags: Exp Clin Transplant Source Type: research

Genetic Polymorphism of HLA-G 14-bp Insertion/Deletion in Pancreas Transplant Recipients and Its Association With Type 1 Diabetes Mellitus.
CONCLUSIONS: Our results provided evidence revealing that the human leukocyte antigen-G insertion / insertion genotype might be involved in the pathogenesis of type 1 diabetes mellitus. PMID: 30702046 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 31, 2019 Category: Transplant Surgery Authors: Rezaei F, Zareei N, Razmi N, Nikeghbalian S, Azarpira N Tags: Exp Clin Transplant Source Type: research

Graft Survival in Patients With Lower Urinary Tract Dysfunction.
Abstract OBJECTIVES: We aimed to the determine urinary tract infection and graft survival rates in pediatric renal transplant recipients with lower urinary tract dysfunction with particular focus on neurogenic bladder, posterior urethral valve, and vesicoureteral reflux nephropathy. MATERIALS AND METHODS: Patients were grouped according to primary diseases as those with and without lower urinary tract dysfunction. Urinary tract infections during year 1 posttransplant were investigated. Estimated glomerular filtration rate was calculated using Schwartz formula. RESULTS: Our study investigated 133 kidney t...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 31, 2019 Category: Transplant Surgery Authors: Kaya Aksoy G, Koyun M, Dinckan A, Aliosmanoglu I, Gemici A, Gultekin E, Comak E, Akman S Tags: Exp Clin Transplant Source Type: research

Development of a National Transplant Program in Montenegro.
Abstract PMID: 30702048 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 31, 2019 Category: Transplant Surgery Authors: Pelicic D, Ratkovic M, Radunovic D, Basic Jukic N Tags: Exp Clin Transplant Source Type: research