Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Influence of Pretransplant Factors on Posttransplant Anemia Recovery Rate in Primary Deceased Donor Kidney Transplant Recipients.
Abstract OBJECTIVES: Our objective was to evaluate the influence of pretransplant risk factors on posttransplant anemia recovery. MATERIALS AND METHODS: This single-center observational retrospective study included 80 deceased donor kidney transplant recipients who had been followed up to 16 months after kidney transplant. Time point of posttransplant anemia recovery was considered the time when hemoglobin of 11.0 g/dL was achieved and maintained for 3 consecutive monthly visits. We collected donor/transplant characteristics (age, sex, hypertension history, cause of death, donor kidney function, expanded crit...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 1, 2021 Category: Transplant Surgery Authors: Lausevic M, Brkovic V, Kravljaca M, Milinkovic M, Baralic M, Gajic S, Naumovic R Tags: Exp Clin Transplant Source Type: research

Nebulized Amphotericin B Dosing Regimen for Aspergillus Prevention After Lung Transplant.
CONCLUSIONS: A systemic antifungal agent combined with nebulized amphotericin either twice or 3 times daily has been effective to prevent Aspergillus infection. Nebulized amphotericin twice daily may be a more viable option to increase a patient's adherence and decrease medication cost and side effects. However, a larger randomized controlled trial is needed to determine the best dosing regimen for nebulized amphotericin B as a fungal prophylaxis after lung transplant. PMID: 33441058 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 1, 2021 Category: Transplant Surgery Authors: Alissa D, AlMaghrabi R, Nizami I, Saleh A, Al Shamrani A, Alangari N, Al Begami N, Al Muraybidh R, Bin Huwaimel S, Korayem GB Tags: Exp Clin Transplant Source Type: research

Small Intestine Posttransplant Lymphoproliferative Disorder in a Kidney Transplant Recipient: A Case Report.
We report on the treatment of a kidney transplant recipient with confirmed isolated posttransplant lymphoproliferative disorder in the small intestine. The patient presented with acute abdomen and small intestine perforation, 17 years after kidney transplant, despite being without calcineurin inhibitor in immunosuppressive therapy, to mitigate previous ductal breast carcinoma. Pathological examinations revealed isolated EpsteinBarr virus-positive diffuse large B-cell non-Hodgkin lymphoma of small intestine, clinical stage IV A E. The patient was treated with reduction of immunosuppression, rituximab, and the CHOP regimen (...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 1, 2021 Category: Transplant Surgery Authors: Radunovic D, Dapcevic M, Prelevic V, Tomovic F, Ratkovic M, Jukic NB Tags: Exp Clin Transplant Source Type: research

Obstructive Uropathy Due to an Unusual Inguinal Hernia 35 Years After Kidney Transplant.
We report the case of a White man, 56 years old, who had previously, at the age of 19 years, undergone a kidney transplant from a deceased donor, to mitigate chronic glomerulonephritis. The patient presented to us with a reducible left inguinal hernia with worsening kidney function, and we used the Lichtenstein hernioplasty technique to surgically repair the hernia, which was followed by an uneventful postoperative course. Existing literature has identified few cases of kidney graft dysfunction due to inguinal hernias. Groin hernia repair of this type in this specific circumstance remains a subject of debate. However, in o...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 1, 2021 Category: Transplant Surgery Authors: Giacomoni A, Hassan R, Vanzulli A, De Carlis L Tags: Exp Clin Transplant Source Type: research

Management of Multiple Renal Arteries and Unusual Venous Anatomy During Kidney Transplant: From a Simple Technical Problem to a Graft-Saving Procedure.
CONCLUSIONS: Vascular anomalies should no longer be considered a contraindication for transplant, if careful anastomosis is performed in every case to avoid ischemia and further complications. Therefore, management of vascular anomalies could be a graftsaving procedure. PMID: 33349206 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Popov Z, Stankov O, Stavridis S, Saidi S, Ivanovski O, Spasovski G, Cakalaroski K, Ivanovski N Tags: Exp Clin Transplant Source Type: research

Hidden Granzyme B-Mediated Injury in Chronic Active Antibody-Mediated Rejection.
CONCLUSIONS: Granzyme B mediates covert graft injury in patients with chronic active antibody-mediated rejection in addition to antibody-mediated injury. PMID: 33349207 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Yadav B, Prasad N, Agarwal V, Agarwal V, Jain M Tags: Exp Clin Transplant Source Type: research

Living Donor Liver Transplant in Patients With Budd-Chiari Syndrome: A Single-Center Experience at Our University Hospital.
CONCLUSIONS: Good survival rates are achievable with living donor liver transplant for patients with advanced Budd-Chiari syndrome, particularly by means of posterior cavoplasty for enlargement of the cava orifice. Therefore, in countries with insufficient deceased donor programs, such as Jordan, living donor liver transplant may be a lifesaving therapeutic possibility. PMID: 33349208 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Obed M, Othman MI, Hammoudi S, Chattab MA, Jarrad A, Bashir A, Obed A Tags: Exp Clin Transplant Source Type: research

Therapeutic Potential of Bama Pig Adipose-Derived Mesenchymal Stem Cells for the Treatment of Carbon Tetrachloride-Induced Liver Fibrosis.
CONCLUSIONS: The findings in this study confirmed that adipose-derived mesenchymal stem cells derived from the Bama pig can be used in the treatment of liver fibrosis, and the grafted adipose-derived mesenchy-mal stem cells can migrate, survive, and differentiate into hepatic cells in vivo. PMID: 33349209 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Wu X, Zhang S, Lai J, Lu H, Sun Y, Guan W Tags: Exp Clin Transplant Source Type: research

En Bloc Kidney Transplant From a Pediatric Donor to a Pediatric Recipient Through a Total Extraperitoneal Approach: A Case Report.
Abstract En bloc kidney transplant remains a technically challenging procedure, especially in pediatric transplants. The intra-abdominal approach has been the preferred operation for very young children. However, the transverse incision could result in more abdominal muscle damage and intra-abdominal adhesions. If the extraperitoneal approach, which is the standard method for adult kidney transplant, could be performed in pediatric recipients, then adverse effects after a transverse incision could be avoided. A 30-month-old female recipient (13.1 kg) underwent an en bloc kidney transplant from a 36-month-old femal...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Yang K, Kim D, Kim S, Ko H, Shim J, Lee T, Ryu J, Kim S, Choi B Tags: Exp Clin Transplant Source Type: research

Role of Fluorodeoxyglucose Positron Emission Tomogram Scan in Sirolimus-Induced Lung Toxicity: A Rare Case Report.
We report a case of 67-year-old man who had living-related renal transplant 12 years previously that was complicated by chronic allograft dysfunction. He presented with fever, cough, and shortness of breath, and his chest imaging showed bilateral patchy and ground glass opacities. Before symptoms of lung toxicity, the patient's sirolimus levels were in the range of high normal. Bronchoalveolar lavage ruled out infection, and a transbronchial biopsy was inconclusive. A fluorodeoxyglucose positron emission tomogram scan showed high uptake in the area of lung opacities with a standard uptake value of 4.7. His symptoms improve...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 1, 2020 Category: Transplant Surgery Authors: Saleemi S, Alothman B, Albaiz F, Alrasheedi S, Shah YZ, Saleemi A Tags: Exp Clin Transplant Source Type: research

Pneumocystis jirovecii Pneumonia in Solid-Organ Transplant Recipients: A National Center Experience.
CONCLUSIONS: The overall prevalence of P. jirovecii pneumonia in solid-organ transplant recipients was similar to other single-center reports. Prophylaxis prevented early posttransplant P. jirovecii pneumonia. However, P. jirovecii pneumonia may develop at any posttransplant stage, and viral infections other than cytomegalovirus should also be considered as a predictor. PMID: 33272151 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Ozgen Alpaydin A, Avkan Oguz V, Cakmakci S, Erguden C, Egeli T, Yildiz S, Derici S, Ozkoc S Tags: Exp Clin Transplant Source Type: research

Epidemiological Characteristics of Corneal Donors at a Tertiary Referral Center in Turkey: An Eye Bank Study.
demir B Abstract OBJECTIVES: The aim of this study was to evaluate the demographic features of corneal donors and available data of corneas in our eye bank during a 14-year period. MATERIALS AND METHODS: The demographic features of the corneal donors, the causes of death, the death-to-excision interval, serology results, the mean endothelial cell density, and the reasons for discarding the corneas were retrospectively evaluated. RESULTS: During the study period, 6524 corneas were retrieved from 3326 donors (76.1% male, 23.9% female). Mean donor age was 43.7 ± 16.0 years (range, 4-75 years; median ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Tanyildiz B, Göktaş E, Günaydın NT, Kaymak NZ, Kanar HS, Kandemir B Tags: Exp Clin Transplant Source Type: research

Factors Affecting Bone Health in Kidney Transplant Recipients: Klotho Gene Single-Nucleotide Polymorphisms and Other Clinical Features.
CONCLUSIONS: Persistent hyperparathyroidism could be an important indicator for development of bone disease in kidney transplant recipients. Also, some of the klotho gene single-nucleotide polymorphisms are associated with higher risk for bone disease after kidney transplant. PMID: 33272153 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Yeter HH, Helvaci O, Korucu B, Gonen S, Guz G, Derici U Tags: Exp Clin Transplant Source Type: research

Liver Transplant for Management of Hepatic Complications of Dyskeratosis Congenita: A Case Report.
Abstract Dyskeratosis congenita, a rare genetic disorder typified by progressive bone marrow failure, is classically characterized by the triad of abnormal skin pigmentation, nail dystrophy, and oral leukoplakia; however, it is a multisystem disease. Although hepatic involvement occurs in about 7% of patients with dyskeratosis congenita, end-stage liver disease is rare. Treatment of dyskeratosis congenita generally involves hematopoietic stem cell transplant. For patients with hepatic failure, liver transplant can be an option. Here, we describe a case of a patient with dyskeratosis congenita who presented with li...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Alebrahim M, Akateh C, Arnold CA, Benissan-Messan D, Chavez JA, Singh N, Al-Adwan Y, El-Hinnawi A, Michaels A, Black SM Tags: Exp Clin Transplant Source Type: research

Upper Extremity Lymphedema Related to Everolimus in a Renal Transplant Recipient: Efficacy of Complete Decongestive Therapy.
We report our experience with a new case of lymphedema of the upper extremity in a renal transplant recipient under treatment with everolimus immunosuppression, and we emphasize the effects of complete decongestive therapy on this chronic condition. PMID: 33272155 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Borman P, Yaman A, Denizli M Tags: Exp Clin Transplant Source Type: research

The Pattern of Cyclosporine Nephrotoxicity and Urinary Kidney Injury Molecule 1 in Allogenic Hematopoietic Stem Cell Transplant Patients.
Abstract OBJECTIVES: The typical immunosuppressive regimen of hematopoietic stem cell transplant includes cyclosporine. However, cyclosporine nephrotoxicity is a concern. We studied cyclosporine nephrotoxicity epidemiology in hematopoietic stem cell transplant patients and compared the pattern and urinary levels of the KIM-1 kidney injury molecule versus serum and urine creatinine levels. MATERIALS AND METHODS: The study covered 10 months at Namazi Hospital, Shiraz, Iran. All patients met the following criteria:> 15 years old, received allogenic hematopoietic stem cell transplant without history of acute o...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Karimzadeh I, Jafari M, Davani-Davari D, Ramzi M Tags: Exp Clin Transplant Source Type: research

Retrospective Analysis of the Comparison Between Single Renal Artery Versus Multiple Renal Arteries in Living Donor Kidney Transplant: Does It Affect the Outcome?
CONCLUSIONS: The safety of kidney transplants of allografts with multiple renal arteries is equal to the safety of transplants of allografts with a single renal artery in terms of vascular complications and acute tubular necrosis, as well as patient and graft survival. PMID: 33272157 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Mahajan AD, Patel ND, Singh Pal L, Bathe S, Darakh PP, Patil M Tags: Exp Clin Transplant Source Type: research

Tacrolimus-Associated Pure Red Cell Aplasia in a Patient With Renal Transplant.
Abstract Pure red cell aplasia is a relatively rare disease characterized by suppression or absence of erythroid precursors while other cell lineages are normal in the bone marrow. The disease could be secondary to other diseases or an adverse side effect of certain drugs. Tacrolimus is widely used as an immunosuppressive agent in solid-organ transplant without significant myelosuppressive effects. However, several tacrolimus-related pure red cell aplasia cases have been reported to date. Here, we report a case of a renal transplant recipient who developed tacrolimus-associated pure red cell aplasia in the posttra...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Yucel OK, Alemdar MS, Akkaya B, Kocak H, Suleymanlar G, Yilmaz VT Tags: Exp Clin Transplant Source Type: research

Liver Allografts From Older Donors With or Without Recovery of Thoracic Organs and Their Impact on Hepatic Graft and Patient Survival.
CONCLUSIONS: Liver procurement with or without recovery of thoracic organs from donors> 60 years old does not affect liver grafts and recipient outcomes in the short-term or long-term and should be encouraged. PMID: 33272159 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Kalayanamitra R, Brooks A, Trakroo S, Kadry Z, Jain A Tags: Exp Clin Transplant Source Type: research

Intraoperative Type I Acute Myocardial Infarction During Liver Transplant Requiring Intra-Aortic Balloon Pump: A Case Report.
We describe a complex case of liver transplant in a 70-year-old male patient with no known history of coronary artery disease, normal preoperative left ventricular function, and negative preoperative cardiac workup who developed progressive intra-operative left ventricular myocardial dysfunction secondary to class I acute myocardial infarction, ultimately requiring intraoperative intra-aortic balloon pump insertion to optimize myocardial perfusion. Management of myocardial ischemia was complicated by bleeding in the setting of coagulopathy necessitating correction. Once hemostasis was achieved, the patient immediately unde...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Ang SS, Rao SH, Rizkalla NA, Cha S, Yang Y, Chacko M, Gurakar AO, Ottmann SE, Pustavoitau A Tags: Exp Clin Transplant Source Type: research

COVID-19 and Liver Transplantation: Early Reports and Recommendations.
PMID: 33272161 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Giannis D, Moris D Tags: Exp Clin Transplant Source Type: research

Influence of an Early Application of Mammalian Target of Rapamycin Inhibitors Everolimus and Sirolimus on Acute Vascular Inflammatory Responses After Ischemia-Reperfusion Injury.
CONCLUSIONS: Early use of mammalian target of rapamycin inhibitors may limit an inflammatory rise of interleukin 6 and vascular endothelial growth factor after ischemia-reperfusion injury and could be associated with a restriction in vascular cell transmigration. PMID: 33272162 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Wenzel M, Haffer H, Wang P, Richter M, Chun FKH, Kornberger A, Beiras-Fernandez A Tags: Exp Clin Transplant Source Type: research

Is Prophylactic Drainage After Pancreas Transplant Associated With Reduced Reoperation Rate?
Abstract OBJECTIVES: Advances in surgery and perioperative care have contributed to improved outcomes after pancreas transplant. However, the development of peripancreatic infections carries a poor prognosis. It is not clear whether abdominal drainage is helpful in collection prevention. MATERIALS AND METHODS: A retrospective review of adult consecutive pancreas transplants at a single institution between January 2017 and December 2018 was undertaken. Postoperative outcomes were compared between patients in whom prophylactic intraoperative drains were placed and patients with no drains. RESULTS: We ident...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Goussous N, St Michel DP, Mcdade H, Gaines S, Borth A, Dawany N, Al-Qaoud T, Bromberg JS, Barth RN, Scalea JR Tags: Exp Clin Transplant Source Type: research

Coronavirus Disease 2019 Pandemic: Early Observations in Abdominal Organ Transplantation.
Abstract The recent COVID-19 outbreak has quickly become a worldwide pandemic emergency. The course of this pandemic is still unknown, with more than 6 million cases identified and over 370 000 deaths globally as of June 1, 2020. The uncertainty and anxiety during this period will have a detrimental effect on the global health system. The organ transplantation field has been negatively affected by the COVID-19 pandemic, especially in regions where the intensity of cases exceeds the available capacity of the health care resources. Recently, scattered data have been published in the English literature, mainly...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 27, 2020 Category: Transplant Surgery Authors: Mahamid A, Fenig Y, Florman S Tags: Exp Clin Transplant Source Type: research

Our Living Donor Protocol for Liver Transplant: A SingleCenter Experience.
CONCLUSIONS: The relationship between donor and recipient and donor safety should be the primary focus for living donor liver transplant. Donor selection should be made carefully to minimize complications and provide adequately functional grafts. PMID: 33187462 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 1, 2020 Category: Transplant Surgery Authors: Karakaya E, Akdur A, Ayvazoglu Soy EH, Harman A, Coskun M, Haberal M Tags: Exp Clin Transplant Source Type: research

Outcome of Pediatric Liver Transplants in Patients With Less Than 10 kg of Body Weight Is Not Worse.
Abstract OBJECTIVES: Liver transplant in pediatric patients with body weight
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 1, 2020 Category: Transplant Surgery Authors: Pandey Y, Varma S, Chikkala BR, Acharya R, Verma S, Balradja I, Das D, Dey R, Agarwal S, Gupta S Tags: Exp Clin Transplant Source Type: research

Renal Transplant Artery Autologous Saphenous Vein Graft Aneurysms: Late Presentation and the Need for Recall and Surveillance.
We report a case of a 45-year-old woman who developed an autologous saphenous vein graft aneurysm 21 years after her living donor transplant, which was successfully managed with explantation of the graft, cold perfusion ex situ, and resection of the aneurysm, which was followed by reconstruction using deceased donor iliac vessels. The graft was then successfully reimplanted. Based on this experience and after a review of the literature related to autologous saphenous vein graft aneurysms in renal transplant, we recommend that surveillance for this particular complication should be considered no later than 10 years after im...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 1, 2020 Category: Transplant Surgery Authors: Hanlon LV, Agostinho N, D'Souza K, Lee T, Chadban S, Pleass HCC, Verran DJ, Laurence JM Tags: Exp Clin Transplant Source Type: research

Kidney Transplantation From a 5-Day-Old Donor With a Single Functioning Kidney.
Abstract Kidney transplant restores renal function in eligible patients with end-stage renal failure who require renal replacement therapy. There remains a significant disparity between the demand and supply of suitable kidneys for transplant. In recent years, pediatric donors have formed an important area for expansion of the donor pool. However, neonatal donation (
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 1, 2020 Category: Transplant Surgery Authors: Varley R, Piscoran O, Picton M, Moinuddin Z, van Dellen D, Augustine T Tags: Exp Clin Transplant Source Type: research

Oxalosis Crystals' Redeposition in Cardiac Tissue Leading to New-Onset Fatal Cardiac Complication After Liver Transplant in Primary Oxalosis Patient: Case Report.
Abstract Primary oxalosis is a rare hereditary disorder of metabolism resulting in accumulation of calcium oxalate in almost all tissues of the body. All published data point out the improvement of cardiac function after transplant. Here, we report the first case in the literature of an 8-year-old patient with primary oxalosis in which oxalosis implantations increased in cardiac tissue after liver transplant and manifested as new-onset ventricular tachycardia and cardiomyopathy, leading to death. PMID: 33187466 [PubMed - in process] (Source: Experimental and Clinical Transplantation : official journal of the ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 1, 2020 Category: Transplant Surgery Authors: AlShalabi O, Ayvazoglu Soy EH, Akdur A, Karakaya E, Kahraman G, Moray G, Haberal M Tags: Exp Clin Transplant Source Type: research

Correlation of miRNAs With Prognosis in Composite Tissue Allotransplantation.
CONCLUSIONS: Defining the clinical findings and immunosuppression-associated pathologies encountered in composite tissue transplant using biomarkers such as microRNA can play an important role in the improvement of these transplant procedures and in predicting patient morbidity. Therefore, the use of microRNAs may be useful in the clinical follow-up of patients who have received composite tissue allotransplant. PMID: 33112219 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2020 Category: Transplant Surgery Authors: Ertosun MG, Özkan Ö, Çelen E, Özkan Ö, Yoldaş B Tags: Exp Clin Transplant Source Type: research

Long-Term Survival After Distal Pancreatectomy With Simultaneous Living-Donor Liver Transplant for Treatment of Pancreatic Insulinoma With Hepatic Metastasis: a Case Report.
Abstract Pancreatic neuroendocrine tumors are a rare type of tumor with malignant potential, characterized by slowgrowth, frequent hepatic metastatic lesions that usually stay contained within the liver. In patients with unresectable liver metastatic pancreatic neuroendocrine tumors, liver transplant is the only treatment available. Insulinomas are the most common pancreatic neuroendocrine tumors, and 5% to 10% of insulinomas are malignant. We herein report a case of a living-donor liver transplant with distal pancreatectomy for a patient with hepatic metastatic pancreatic insulinoma with a 13-year postoperative s...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Ohya Y, Hayashida S, Inomata Y Tags: Exp Clin Transplant Source Type: research

Prolonged Extracorporeal Membrane Oxygenation Support as a Bridge to Heart Transplant.
We present a case of a patient bridged to transplant with 5 months of extracorporeal membrane oxygenation support. PMID: 32967595 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Sert DE, Kervan U, Kocabeyoglu SS, Karahan M, San I, Bekgoz B, Ozatik A Tags: Exp Clin Transplant Source Type: research

Diagnostic Value of Flow Cytometry in Kidney Transplant Recipients With Active Pulmonary Tuberculosis.
CONCLUSIONS: Analysis of peripheral lymphocyte subsets is helpful in the early diagnosis of kidney transplant recipients with active pulmonary tuberculosis. It should be added into routine examinations of kidney transplant recipients who have an ambiguous diagnosis between active pulmonary tuberculosis and bacterial pneumonia. PMID: 32967596 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Yi W, Cheng K Tags: Exp Clin Transplant Source Type: research

Living Donor Liver Transplant for Dengue-Related Acute Liver Failure: A Case Report.
Abstract Dengue is a common viral infection, especially in tropical countries, and it is a well-known cause of acute liver failure. The effects on the liver range from a mild illness to acute liver failure. Dengue-related acute liver failure has a high mortality rate, and the role of liver transplant in such cases has been less studied, due to the rapid progression and often associated multiorgan dysfunction in severe cases. Here, we report the first living donor liver transplant for an acute liver failure due to dengue. Although liver transplant is not the choice of treatment for sick patients, timely interventio...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Chikkala BR, Pandey Y, Acharya R, Sreekumar S, Dey R, Agarwal S, Gupta S Tags: Exp Clin Transplant Source Type: research

Prophylactic Wound Drainage in Renal Transplant: A Survey of Practice Patterns in Australia and New Zealand.
CONCLUSIONS: Although drain insertion is a common practice, transplant surgeons in Australia and New Zealand reported sufficient uncertainty concerning the potential benefits and harms to warrant design and conduct of a randomized controlled trial. PMID: 32967598 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Mugino M, Lee T, Lam S, Hameed A, Sandroussi C, Chadban S, Pleass H, Laurence JM Tags: Exp Clin Transplant Source Type: research

Success Rate of Grafts With Multiple Renal Vessels in 3136 Kidney Transplants.
CONCLUSIONS: Improved anastomosis and recon struction techniques have allowed the safe transplant of multiple renal vessel grafts that may remain functional for many years. PMID: 32967599 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Karakaya E, Akdur A, Ayvazoğlu Soy E, Moray G, Haberal M Tags: Exp Clin Transplant Source Type: research

Outcome of Children With Intestinal Failure Due to Waardenburg Syndrome From an Intestinal Transplant Center: A Case Series.
Abstract Waardenburg syndrome is a genetic disease characterized by hearing loss and pigmentation abnormalities. Waardenburg syndrome type 4 is very rare, and children with Waardenburg syndrome type 4 present with intestinal aganglionosis. The associated findings and severity of Waardenburg syndrome type 4 may also differ significantly between cases. Intestinal insufficiency is probable and creates difficulties in terms of treatment; intestinal transplant may be required. In this case report, we present 4 cases of patients with Waardenburg syndrome who have intestinal issues, 2 of whom underwent small bowel transp...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Cagan Appak Y, Tinastepe T, Aksoy B, Turhan S, Tugmen C, Sert I, Baran M Tags: Exp Clin Transplant Source Type: research

Early Projection of Kidney Allograft Rejection Through Deep Learning: A Way Forward.
PMID: 32967601 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Al-Qahtani AA, Alenzi AAS, Jandani R, Shoukat Ali A Tags: Exp Clin Transplant Source Type: research

Liver Transplant for Nonresectable Colorectal Cancer Liver Metastases in South Africa: A Single-Center Case Series.
CONCLUSIONS: To our knowledge, this is the only published case series of patients undergoing liver transplant for nonresectable colorectal carcinoma in Africa and is internationally unique in its use of expanded criteria and marginal grafts for this type of transplant. Despite the use of such grafts in our recipients, thus far, these outcomes align with those of the 2013 Secondary Cancer cohort studies from Norway. PMID: 32967602 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Botha J, Demetriou G, Fabian J, Etheredge H Tags: Exp Clin Transplant Source Type: research

Transplant Immunosuppression Management and COVID-19.
PMID: 32967603 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Giannis D, Ziogas IA, Esagian SM, Matenoglou E, Moris D Tags: Exp Clin Transplant Source Type: research

Comparison of Corneal Densitometry Between Penetrating Keratoplasty and Deep Anterior Lamellar Keratoplasty in Keratoconus Patients.
Ö Abstract OBJECTIVES: Our aim was to compare corneal densitometry values in keratoconic eyes undergoing deep anterior lamellar keratoplasty with the "big bubble" and manual lamellar dissection techniques, as well as penetrating keratoplasty. MATERIALS AND METHODS: This retrospective study evaluated the postoperative outcomes of 31 eyes treated with big bubble-deep anterior lamellar keratoplasty, 23 eyes with manual lamellar dissectiondeep anterior lamellar keratoplasty, and 37 eyes with penetrating keratoplasty. Corneal densitometry, best corrected visual acuity, and other corneal tomographic...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Karaca EE, Özek D, Evren Kemer Ö Tags: Exp Clin Transplant Source Type: research

Self-Care Education Program as a New Pathway Toward Improving Quality of Life in Kidney Transplant Patients: A Single-Blind, Randomized, Controlled Trial.
CONCLUSIONS: A self-care education program is a more effective approach to improve the knowledge and skills of transplant patients. Thus, we suggest an emphasis on teaching self-care knowledge and skills for transplant patients in nursing care education programs. This can ultimately lead to quality of life improvement in kidney transplant patients. PMID: 32967605 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 16, 2020 Category: Transplant Surgery Authors: Aghakhani N, Hemmati Maslakpak M, Jalali S, Parizad N Tags: Exp Clin Transplant Source Type: research

Liver Transplant for Posthepatectomy Liver Failure in Hepatoblastoma.
CONCLUSIONS: When the predictive remnant liver volume by computed tomography-volumetry before extended hepatectomy for patients with hepatoblastoma is less than 40%, the possibility of posthepatectomy liver failure should be recognized. PMID: 32799783 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 14, 2020 Category: Transplant Surgery Authors: Hirata Y, Sanada Y, Omameuda T, Katano T, Miyahara G, Yamada N, Okada N, Onishi Y, Sakuma Y, Sata N Tags: Exp Clin Transplant Source Type: research

Renal Warm Ischemia in Organ Donors After Circulatory Death.
This article describes the pathophysiology of warm ischemia and summarizes recent developments in technological and methodological practices that mitigate the mechanisms of warm ischemia. Anoxia, mitochondrial dysfunction, calcium overload, oxidative and nitrosative stress, immune response, and no reflow are the main mechanisms by which ischemia leads to cell death and organ dysfunction. In situ oxygenated recirculation, abdominal normothermic organ recirculation, abdominal hypothermic organ recirculation, and ex vivo machine perfusion ensure continued organ perfusion and prevent prolonged warm ischemia in organ donation. ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 14, 2020 Category: Transplant Surgery Authors: Santos Dias F, Metelo Coimbra C, Roncon-Albuquerque R Tags: Exp Clin Transplant Source Type: research

Gene Expression of Toll-Like Receptors 2 and 4 in Renal Transplant Rejection.
CONCLUSIONS: Toll-like receptors 4 and 2 could increase the risk of acute rejection after renal transplant and could be defined as a risk factor for rejection. Further studies are recommended. PMID: 32799786 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 14, 2020 Category: Transplant Surgery Authors: Heidari M, Ebadi P, Abbasi S, Afshari A, Yaghobi R, Salehipour M, Karimi MH Tags: Exp Clin Transplant Source Type: research

Effect of Opt-out System for Organ Donation After Brain Death on Ethical Legitimacy and Potential Efficacy in a Mathematical Model.
CONCLUSIONS: An opt-out system can increase the number of organ donors; however, achievement of negative autonomy can decrease. PMID: 32799789 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 14, 2020 Category: Transplant Surgery Authors: Kim SW, Lee HY, Park UJ, Kim HT, Roh YN Tags: Exp Clin Transplant Source Type: research

Impact of Matrix Metalloproteinases 2 and 9 and Tissue Inhibitor of Metalloproteinase 2 Gene Polymorphisms on Allograft Rejection in Pediatric Renal Transplant Recipients.
In this study, we aimed to investigate functional polymorphisms of MMP2, MMP9, and TIMP2 genes in pediatric renal transplant recipients. MATERIALS AND METHODS: Our study included 68 kidney transplant recipients and 58 control patients. The kidney transplant recipient group was further divided into 2 subgroups: no graft rejection (n = 47) and graft rejection (n =21). MMP2 -735C>T (rs2285053), MMP2 -1306C>T (rs243865), MMP2 -1575G>A (rs243866), MMP9 c.-1562C>T (rs3918242), TIMP2 -418G>C (rs8179090), and TIMP2 303C> T (rs2277698) polymorphisms were analyzed with the use of polymerase chain reaction and ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 13, 2020 Category: Transplant Surgery Authors: Akad Dincer S, Sahin FI, Terzi YK, Gulleroglu K, Baskin E, Haberal M Tags: Exp Clin Transplant Source Type: research

Changes in Muscle Quality and Body Composition 1 Year After Hand-Assisted Laparoscopic Donor Nephrectomy in Living Kidney Donors.
Abstract OBJECTIVES: Our aim was to investigate effects of surgery on living donors' body composition and clarify factors related to it. MATERIALS AND METHODS: We evaluated preoperative computed tomography images of 335 living kidney donors (127 men, 209 women) to calculate 3 body composition parameters and changes with aging by sex: (1) skeletal muscle mass, quantified by skeletal muscle index; (2) fat distribution, calculated by visceral adipose tissue/subcutaneous adipose tissue ratio; and (3) muscle quality, quantified by intramuscular adipose tissue content. Thereafter, with pre- and postoperative comput...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 13, 2020 Category: Transplant Surgery Authors: Fukuhara H, Nawano T, Kanda A, Tomosugi T, Okada M, Futamura K, Hiramitsu T, Goto N, Narumi S, Watarai Y Tags: Exp Clin Transplant Source Type: research

Ischemic-Type Biliary Lesions After Liver Transplant: Factors Causing Early-Onset Versus Late-Onset Disease.
CONCLUSIONS: This study serves as a supplement to current data and the understanding of ischemic-type biliary lesions with emphasis on the relevance of disease onset and causes. We could in fact determine transfusion of blood products as a determinant of an early onset of ischemic-type biliary lesion. Bilirubin could be a surrogate marker for ischemic-type biliary lesions, especially in its early-onset form. PMID: 32799788 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 13, 2020 Category: Transplant Surgery Authors: Dobrindt EM, Eurich D, Veltzke-Schlieker W, Pratschke J, Sauer I, Öllinger R, Schmuck RB Tags: Exp Clin Transplant Source Type: research

Overview of the JACIE Accreditation: A Single-Center Experience from the First Application to Third Accreditation.
PMID: 32778011 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 6, 2020 Category: Transplant Surgery Authors: Tepebası S, Kozanoglu I, Yeral M, Boga C, Ozdogu H Tags: Exp Clin Transplant Source Type: research