Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Left Renal Vein Ligation for Spontaneous Splenorenal Shunts During Deceased-Donor Orthotopic Liver Transplant Is Safe and Can Mitigate Complications from Portal Steal: A Case Series.
CONCLUSIONS: Left renal vein ligation is technically feasible, has minimal and transient effects on renal function, and can improve portal venous flow, thus mitigating the risk for portal vein thrombus, graft hypoperfusion, and possible dysfunction. PMID: 30501587 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 28, 2018 Category: Transplant Surgery Authors: Nguyen MC, Sage Silski L, Alebrahim M, Black S, Elkhammas E, Washburn K, El-Hinnawi A Tags: Exp Clin Transplant Source Type: research

Posttransplant Erythrocytosis Among Egyptian Living-Donor Kidney Transplant Recipients.
Abstract OBJECTIVES: The goal when treating patients with end-stage renal disease is to increase patient survival and to provide a better quality of life, both of which can be achieved by kidney transplant. Identifying problems associated with kidney transplant is an essential step toward improved graft function. Here, we evaluated posttransplant erythrocytosis, a frequent complication among kidney transplant recipients. MATERIALS AND METHODS: In this single-center retro-spective study, we identified 1850 kidney transplant recipients who were transplanted at the Mansoura Urology and Nephrology Center (Mansour...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 28, 2018 Category: Transplant Surgery Authors: Abouelenein RK, Refaie AF, Alhendy YA, Al Okily AM, Elserwy NA, Mashaly ME, Abbas MH, Bakr MA Tags: Exp Clin Transplant Source Type: research

Impact of Type 1 and Type 2 Diabetes Mellitus on Pancreas Transplant Outcomes.
Abstract OBJECTIVES: Pancreas transplant improves quality of life and survival of patients irrespective of pretransplant C-peptide levels. Our objectives were to examine complications and outcomes in patients without measureable C-peptide (insulin-dependent type 1 diabetes mellitus) and carefully selected patients with measurable C-peptide (insulin-dependent type 2 diabetes mellitus) after pancreas transplant. MATERIALS AND METHODS: We conducted a retrospective analysis to examine the demographic, transplant factors, complications, and outcomes in patients with nondetectable pretransplant C-peptide (insulin-d...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 28, 2018 Category: Transplant Surgery Authors: Rohan V, Taber D, Palanisamy A, Mcgillicuddy J, Chavin K, Baliga P, Bratton C Tags: Exp Clin Transplant Source Type: research

Attitudes Toward Organ Donation and Transplantation Among Transplant-Related Health Care Workers and the Local Population of Montenegro.
CONCLUSIONS: There is a need to increase the generosity of the Montenegrin population and its health care workers regarding organ donation at all times and not exclusively on specific occasions. PMID: 30398096 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Pelicic D, Vukcevic B, Bokan D, Stojanovic V, Radojevic N Tags: Exp Clin Transplant Source Type: research

Comparison of Standard and Modified Standard Organ Procurement Techniques for Deceased Donors.
This study aimed to compare the impact of deceased-donor organ procurement techniques (standard versus modified standard) on biochemical outcomes after liver transplant. MATERIALS AND METHODS: From February 2006 to December 2013, organs were recovered from 105 consecutive deceased donors by our transplant team. All organ procurement procedures were performed by a pioneer surgeon experienced in organ recovery from deceased donors. Donors were divided into those who had the abdominothoracic approach, which is referred to as the standard technique, and those who had the abdominal approach, which is referred to as the mod...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Koc C, Akbulut S, Yilmaz S Tags: Exp Clin Transplant Source Type: research

Acoustic Radiation Force Impulse Elastography Findings of Achilles Tendons in Patients on Chronic Hemodialysis and in Renal Transplant Patients.
Abstract OBJECTIVES: The Achilles tendon, which is composed of tendinous parts of gastrocnemius and soleus muscles, is the strongest and the largest tendon in the human body. Chronic renal disease can lead to reduced physical activity and exercise capacity. Spontaneous rupture of the Achilles tendon can occur in patients with chronic renal failure, with recurrent microtraumas, hypoxia, and chronic acidosis as predisposing factors. Here, we assessed and compared the elastographic findings in the Achilles tendon using acoustic radiation force impulse elastography in patients on chronic hemodialysis, in renal transpl...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Kural Rahatli F, Turnaoglu H, Haberal KM, Kirnap M, Fidan C, Sayın CB, Uslu N, Haberal M Tags: Exp Clin Transplant Source Type: research

De Novo Primary Liver Cancer After Liver Transplantation: A French National Study on 15803 Patients.
, Altieri M Abstract PMID: 30398099 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Allaire M, Sérée O, Coilly A, Houssel-Debry P, Neau-Cransac M, Pageaux GP, Dumortier J, Altieri M Tags: Exp Clin Transplant Source Type: research

Use of Computed Tomography Volumetry to Assess Liver Weight in Patients With Cirrhosis During Evaluation Before Living-Donor Liver Transplant.
In this study, we evaluated the accuracy of freehand computed tomography volumetry to assess total liver volume by comparing weights of total hepatectomy specimens in patients with cirrhosis. For our analyses, we considered the density of a cirrhotic liver to be 1.1 kg/L. MATERIALS AND METHODS: Liver volume was measured using a freehand computed tomography technique in 52 patients with cirrhosis from different causes and who had no solid lesions before transplant. Measurements were made with a 16-slice multidetector computed tomography scanner (Siemens Somatom Sensation 16, Erlangen, Germany). For volumetric measureme...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Haberal KM, Kural Rahatlı F, Turnaoğlu H, Özgün G, Coşkun M Tags: Exp Clin Transplant Source Type: research

Simultaneous Pancreas-Kidney Transplant After Bricker Loop Urinary Diversion: A Case Report.
Baranski AG Abstract Simultaneous pancreas-kidney transplant is the ultimate therapy for patients who have uncontrolled and complicated type 1 diabetes mellitus with end-stage renal disease. The combined pancreas transplant provides a euglycemic milieu for the kidney and protects it from recurrence of diabetic complications. Our patient, a 41-year-old woman with end-stage diabetic nephropathy and history of multiple abdominal surgeries (ovarian cyst fenestration, adnexal extirpation, abdominal wall reconstruction), including urinary diversion (Bricker loop, above double J stent), underwent simultaneous pancreas-ki...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 6, 2018 Category: Transplant Surgery Authors: Kovács DÁ, Braat AE, Huurman VAL, Baranski AG Tags: Exp Clin Transplant Source Type: research

Long-Term Outcome of Veno-Occlusive Disease After Liver Transplant: A Retrospective Single-Center Experience.
CONCLUSIONS: A tailored approach based on clinical features and including retransplant can achieve acceptable long-term survival in patients with veno-occlusive disease after liver transplant. PMID: 30381049 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Patrono D, Marola S, David E, Chiusa L, Martini S, Mirabella S, Lupo F, Salizzoni M, Romagnoli R Tags: Exp Clin Transplant Source Type: research

Outcomes of Kidney Transplant Recipients With Posttransplant Genitourinary Infectious Complications: A Single Center Study.
CONCLUSIONS: Kidney transplant recipients who develop urinary tract infections within 6 months of transplant may be at increased risk of graft failure or patient death; however, further studies are needed to elucidate the relationship between posttransplant infections and long-term outcomes. PMID: 30381050 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Srinivasan D, Stoffel JT, Bradley K, Sung RS Tags: Exp Clin Transplant Source Type: research

How to Manage Kidney Transplant Recipients: Deciding Between Glomerular Filtration Rate-Estimating Equations, Creatinine Clearance and Albumin-Creatinine Ratio, or Albumin Excretion.
ríguez F, Bailén García MA Abstract OBJECTIVES: Management of renal transplant recipients involves measuring glomerular filtration rate and albuminuria; however, data are conflicting on the use of estimating equations or creatinine clearance and albumin-creatinine ratio in early morning urine or albumin excretion in 24-hour urine. We aimed to determine the performance of creatinine clearance and 3 estimated creatinine-based formulas and compare the usefulness of albumin-creatinine ratio related to albumin excretion in kidney transplant patients. MATERIALS AND METHODS: This cross-sectional...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: López-Pelayo I, Mazuecos Blanca MA, García Palacios MV, Galán Sánchez F, López Rodríguez F, Bailén García MA Tags: Exp Clin Transplant Source Type: research

Impact of Primary Disease Nature in the Development of De Novo Donor-Specific Antibodies After Kidney Transplant and the Risk of Acute Rejection.
In this study, we explored the effect of the primary disease nature on development of de novo donor-specific antibodies after kidney transplant. MATERIALS AND METHODS: We retrospectively studied kidney transplant recipients based on their primary disease. Patients were divided according to autoimmune and nonautoimmune diseases. The frequency of de novo donor-specific antibodies posttransplant and the incidence of acute rejection were estimated. De novo donor-specific antibodies were determined by the Luminex (LAB Screen products, One Lambda, Inc., Canoga Park, CA, USA) assay. RESULTS: Our study included 228 patie...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Lionaki S, Pappas A, Altanis N, Kapsia H, Liapis G, Vittoraki A, Iniotaki A, Zavos G, Boletis JN Tags: Exp Clin Transplant Source Type: research

Abdominal Wall Transplant Surgery.
Abstract The evolution and success of intestinal and multi-visceral transplantation over the past 20 years have raised the issue of difficult or even impossible abdominal closure, a topic rarely encountered in other fields of transplantation. Different techniques have been proposed to address this topic. The choice depends on the transplant team's expertise and/or the availability of a plastic surgery service. Abdominal wall transplant is a type of composite tissue allograft that can be utilized to reconstitute the abdominal domains of patients who undergo intestinal transplant, and the results are encouraging. It...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Park SH, Eun SC Tags: Exp Clin Transplant Source Type: research

Twice-Weekly Tacrolimus Can Overcome Pharmacologic Interaction and Help in the Successful Treatment of Pulmonary Aspergillosis in a Liver Transplant Recipient.
Abstract Drug-drug interactions between azoles and calcineurin inhibitors can cause issues for organ transplant specialists. Clinical practice guidelines for the treatment of solid-organ transplant recipients with invasive aspergillosis infection are lacking. Here, we present a patient who developed pulmonary aspergillosis after liver transplant. The patient had prolonged treatment with echinocandin that was not effective. A drug-drug interaction between azoles and tacrolimus caused issues for the clinical physician. We adjusted the doses, and the patient was successfully treated. A reduction in the tacrolimus dos...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Chiu YC, Ho MH, Chen TW, Hsieh CB, Fan HL Tags: Exp Clin Transplant Source Type: research

Successful Treatment of a Rare Complication in a Heart Transplant Recipient: Spontaneous Axillary Artery Bleeding.
In this report, we present a case of spontaneous axillary artery bleeding in a heart transplant recipient. PMID: 30373508 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Karaçağlar E, Akgün AN, Aytekin C, Aydınalp A, Sezgin A, Müderrisoğlu IH Tags: Exp Clin Transplant Source Type: research

Effect of Parathyroidectomy Timing in Kidney Transplant Recipients on Graft Function.
Abstract OBJECTIVES: Persistent hyperparathyroidism can have a deleterious effect on graft function in kidney transplant recipients, although serum calcium, phosphorus, and parathyroid hormone levels tend to normalize after successful transplant. Parathyroidectomy can result in sustained amelioration of persistent hyperparathyroidism despite graft failure risk and unfavorable graft outcomes. Data on this issue are limited and conflicting. Here, we evaluated the effects of parathyroidectomy on graft function in kidney transplant recipients. MATERIALS AND METHODS: This retrospective study included 249 adult kid...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Oruc A, Ersoy A, Yildiz A, Oz Gul O, Ersoy C Tags: Exp Clin Transplant Source Type: research

Significance of Occult Hepatitis C Virus Infection in Liver Transplant Patients With Cryptogenic Cirrhosis.
CONCLUSIONS: A finding of hepatitis C virus RNA in liver tissue samples of transplant recipients presents the historical possibility of occult hepatitis C virus infection as underlying disease in our patients with cryptogenic cirrhosis. Results present an important and determinative role of occult hepatitis C virus infection in the pathogenesis of cryptogenic cirrhosis, which needs further confirmation in additional studies. PMID: 30346262 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Yaghobi R, Kazemi MJ, Geramizadeh B, Malek Hosseini SA, Moayedi J Tags: Exp Clin Transplant Source Type: research

Immediate Tracheal Extubation After Pediatric Liver Transplantation.
We examined whether immediate tracheal extubation among pediatric liver transplant recipients was safe and feasible. MATERIALS AND METHODS: We retrospectively analyzed medical records of pediatric liver transplant recipients at Baskent University Hospital from January 2012 to December 2017. We grouped children who were extubated in the operating room versus those extubated in the intensive care unit. RESULTS: In our study group of 81 pediatric patients, median age was 4 years (range, 4 mo to 16 y) and 44 (54%) were male. Immediate tracheal extubation in the operating room was performed in 39 patients (48%). Child...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Sahinturk H, Ozdemirkan A, Yilmaz O, Zeyneloglu P, Torgay A, Pirat A, Haberal M Tags: Exp Clin Transplant Source Type: research

Complications and Outcomes of Endoscopic Treatment in a Cohort of Patients With Biliary Stenosis After Orthotopic Liver Transplant: A Retrospective Observational Study.
CONCLUSIONS: Preoperative recipient conditions and postoperative morbidities may represent risk factors for development of biliary strictures. Consequently, the optimal endoscopic treatment should be tailored to the type and the onset of stenosis and the patient's condition. PMID: 30346264 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Bortolasi L, Violi P, Carraro A, Montin U, Cerofolini A, Munari A, Eccher A, Gramignoli R, Bovo C, Tedeschi U Tags: Exp Clin Transplant Source Type: research

Potentials of Differentiated Human Cord Blood-Derived Unrestricted Somatic Stem Cells in Treatment of Liver Cirrhosis.
CONCLUSIONS: The use of unrestricted somatic stem cells, isolated and propagated from cord blood and then differentiated into hepatocyte-like cells, improved both fibrosis and normal function of cirrhotic livers. These cells could be considered as a line of cell-based therapy in cases of chronic liver disease. PMID: 30346265 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: El Baz H, Demerdash Z, Kamel M, Atta S, Salah F, Hassan S, Hammam O, Khalil H, Bayoumi A Tags: Exp Clin Transplant Source Type: research

Normal Primary Graft Function Despite Early Hepatic Artery Thrombosis After Living-Donor Liver Transplant.
CONCLUSIONS: Early hepatic artery thrombosis is not always associated with graft dysfunction. Retransplant is still necessary due to ischemic cholangiopathy in the long-term follow-up. However, an elective retransplant, which could mean better outcomes, should be preferred instead of an emergency retransplant. PMID: 30346266 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Alim A, Erdogan Y, Dayangac M, Yuzer Y, Tokat Y, Oezcelik A Tags: Exp Clin Transplant Source Type: research

Systematic Screening Using Luminex for De Novo C3d Fixing of Class II Donor-Specific Antibodies Is Correlated With Luminex Mean Fluorescence Intensity in Renal Transplant Patients.
CONCLUSIONS: These results further reinforce the paradigm that the higher the mean fluorescence intensity, the more complement activation occurs. Routine C3d testing is thus unnecessary in this setting. PMID: 30346267 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Villemaire M, Jouve T, Bourdin A, Janbon B, Pinel N, Tetaz R, Terrier N, Rostaing L, Masson D, Malvezzi P Tags: Exp Clin Transplant Source Type: research

Percutaneous Recanalization of Anastomotic Portal Vein in a Pediatric Patient After Liver Transplant Without Any Recognizable Portal Vein Remnant on Imaging.
Abstract In patients with complete portal vein thrombosis, the main portal vein is obstructed, resulting in development of hepatopetal collateral vessels. In cases of complete portal vein thrombosis, interventional procedures are challenging, with the greatest difficulty in the form of passing the guide wire across the level of obstruction. A recognizable main portal vein remnant has been deemed as a mandatory criterion in previous reports. Here, we report a case of cavernous trans-formation of the portal vein in a pediatric patient after liver transplant who had no obvious detectable portal vein remnant on radiol...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 19, 2018 Category: Transplant Surgery Authors: Gupta A, Gangwani G, Mehta N, Wadhwa N, Ghuman S, Yadav A Tags: Exp Clin Transplant Source Type: research

Thrombophilic Genetic Anomalies and Their Association With Dialysis Initiation Age in a Cohort of Lebanese Hemodialysis Patients.
Abstract OBJECTIVES: The relationship between chronic kidney disease and cardiovascular disease is complex and bidirectional. This relationship may be partially linked to thrombophilic genetic anomalies that may predispose to the progression of both diseases. MATERIALS AND METHODS: We analyzed blood samples from 102 Lebanese patients with end-stage renal disease and undergoing hemodialysis and 20 randomly selected healthy volunteers for frequencies of 12 cardiovascular disease gene mutations and traditional risk factors. The frequencies of these mutations were calculated and compared in both groups. We strati...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 15, 2018 Category: Transplant Surgery Authors: Barbari A, Milane A, Salameh P, Abi Younis J, El Houjairy A, Safi K, Sabaa Ayoun I, Jaafar M, Bou Khalil L, Bachir A, Bassil N, Karnib H, Morad N, Rizk S, Masri M Tags: Exp Clin Transplant Source Type: research

Black Ethnicity is Not a Risk Factor for Mortality or Graft Loss After Kidney Transplant in the United Kingdom.
Abstract OBJECTIVES: There are conflicting reports in the literature regarding outcomes after kidney transplant for patients of black ethnicity. To investigate further, we compared outcomes for black versus white kidney transplant recipients in a single UK transplant center. MATERIALS AND METHODS: We analyzed 1066 kidney transplant recipients (80 black patients, 986 white patients) within a single-center cohort (2007-2017) in the United Kingdom, with cumulative 4446 patient-year follow-up. Data were electronically extracted from the Department of Health Informatics database for every study recruit, with manua...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Williams A, Richardson C, McCready J, Anderson B, Khalil K, Tahir S, Nath J, Sharif A Tags: Exp Clin Transplant Source Type: research

Upper Extremity Compartment Syndrome Following Radial Artery Puncture in a Patient Undergoing Orthotopic Liver Transplant.
Abstract Acute compartment syndrome is the physiologic consequence of increasing pressures within an enclosed anatomic space; if left untreated, it can subsequently cause irreversible necrosis, nerve injury, and tissue damage. A number of iatrogenic causes have been reported in the literature; however, to the best of our knowledge, there are no prior reports of upper extremity compartment syndrome in orthotopic liver transplant following arterial line placement. Here, we report a 52-year-old male with a history of end-stage liver disease secondary to primary sclerosing cholangitis who presented for orthotopic live...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Lipton M, Aniskevich S Tags: Exp Clin Transplant Source Type: research

Impact of Transplant Nephrectomy for Patient Survival Over the Past 15 Years: A Single-Center Study.
Abstract OBJECTIVES: How transplant nephrectomy affects patient survival after return to dialysis is unclear. Here, we compared patient survival after graft loss between patients with and without transplant nephrectomy. MATERIALS AND METHODS: We divided 171 patients who received transplant between 2000 and 2015 and had graft loss into 3 groups: 64 had graft failure left in situ (without nephrectomy), 51 had nephrectomy 3 months posttransplant (late nephrectomy). The primary endpoint was patient survival. Risk factors for patient death were also analyzed. Secondary endpoints included relisting for transplant a...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Muramatsu M, Hyodo Y, Sheaff M, Aikawa A, Yaqoob M, Puliatti C Tags: Exp Clin Transplant Source Type: research

Use of Rotational Thromboelastometry in Liver Transplantation Is Associated With Reduced Transfusion Requirements.
Abstract OBJECTIVES: Increased transfusion requirements in liver transplantation have been reported to be associated with worsened outcomes, more frequent reinterventions, and higher expenses. Anesthesiologists might counteract this through improved coagulation management. We evaluated the effects of rotational thromboelastometry on transfusion and coagulation product requirements and on outcome measurements. MATERIALS AND METHODS: Patients who were 14 years or older and who were undergoing liver transplant at Hannover Medical School between January 2005 and December 2009 were included in this retrospective a...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Schumacher C, Eismann H, Sieg L, Friedrich L, Scheinichen D, Vondran FWR, Johanning K Tags: Exp Clin Transplant Source Type: research

Incidence of Post-Liver Transplant Hepatic Dysfunction After Sustained Virologic Response Following Direct-Acting Anti-Hepatitis C Therapy.
CONCLUSIONS: During the study period, 10% of patients experienced hepatic dysfunction after sustained viral response. Presumed causative factors included partial immune reconstitution and nonalcoholic fatty liver disease. PMID: 30295586 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Jain A, Riley TR, Krok KL, Schreibman I, Karamchandani DM, Liao X, Tian Y, Dohi T, Kadry Z Tags: Exp Clin Transplant Source Type: research

A Single-Center Experience With Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphoblastic Leukemia: A Modest Pitch for Non-Total Body Irradiation Conditioning Regimens.
We report our experience with radiation-free conditioning using busulfan and cyclophosphamide in 127 pediatric patients with acute lymphoblastic leukemia who were treated between 1997 and 2014. The median age was 11 years (range,
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Hamidieh AA, Eslami Shahre Babaki A, Rostami T, Kasaeian A, Koochakzadeh L, Sharifi Aliabadi L, Behfar M, Ghavamzadeh A Tags: Exp Clin Transplant Source Type: research

N-Acetylcysteine and Benfotiamine Protect Autotransplanted Ovarian Tissue From Ischemia-Reperfusion Injury: An Experimental Study.
CONCLUSIONS: In autologous intraperitoneal ovarian transplant, both benfotiamine and N-acetylcysteine are equal and effective agents in protection of ovarian tissue against ischemic injury. PMID: 30295588 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Tuncer S, Atilgan R, Pala Ş, Kuloğlu T, Artaş G, Aydın S Tags: Exp Clin Transplant Source Type: research

Association Between Sarcopenia and Functional Status in Liver Transplant Patients.
CONCLUSIONS: Provider-assessed physical health status moderately correlates with objective measures of frailty. PMID: 30295589 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 5, 2018 Category: Transplant Surgery Authors: Dolgin NH, Smith AJ, Harrington SG, Movahedi B, Martins PNA, Bozorgzadeh A Tags: Exp Clin Transplant Source Type: research

Cervical Spinal Ependymoma With Hemorrhage in a Renal Transplant Patient.
l;zen Ö, Haberal M Abstract Ependymomas are the most common intramedullary spinal tumors in adults and constitute around 20% of all spinal tumors in adults. There are 3 subgroups of ependymomas according to World Health Organization classification: subependymoma or myxopapillary (grade 1), ependymoma (grade 2), and anaplastic (grade 3). Therapy for patients is aimed at safe and total surgical removal and, in selected cases, postoperative radiotherapy. Bleeding from a spinal ependymoma, with subsequent urgent surgery, is extremely rare. Here, we present a case of a renal transplant patient who had a cervical e...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Şahintürk F, Dere ÜA, Kırnap M, Sönmez E, Altınörs N, Özen Ö, Haberal M Tags: Exp Clin Transplant Source Type: research

Neoadjuvant Transarterial Chemoembolization Improves Survival After Liver Transplant in Patients With Hepatocellular Carcinoma.
Abstract OBJECTIVES: Our aims were to determine whether transarterial chemoembolization before liver transplant for hepatocellular carcinoma improves posttransplant survival and whether patients downstaged by transarterial chemoembolization within Milan criteria have a posttransplant survival benefit. MATERIALS AND METHODS: In this retrospective analysis of prospectively collected data, survival rates of 87 patients treated with and 68 patients not treated with transarterial chemoembolization before liver transplant were compared using 2-sample t tests and multivariate Cox regression. We also compared posttra...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Werner JD, Frangakis C, Ruck JM, Hong K, Philosophe B, Cameron AM, Saberi B, Gurakar A, Georgiades C Tags: Exp Clin Transplant Source Type: research

Relationship Between Preoperative Diastolic Transpulmonary Gradient With Pulmonary Vascular Resistance and 1-Year and Overall Mortality Rates Among Patients Undergoing Cardiac Transplant.
H, Haberal M Abstract OBJECTIVES: Cardiac transplant is a life-saving procedure for patients with end-stage heart failure. Preoperative pulmonary vascular resistance is indicative of intrinsic pulmonary vascular disease and correlates with posttransplant survival. However, its measurement is costly and time consuming. Therefore, simpler techniques are required. Diastolic transpulmonary gradient reportedly indicates intrinsic pulmonary vascular disease. Here, we investigated the relationship between preoperative diastolic transpulmonary gradient with preoperative pulmonary vascular resistance and 1-year and overal...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Çiftci O, Ünal EN, Dellaloğlu Z, Aydan A, Aksoy G, Karakaş M, Aydınalp A, Sezgin A, Müderrisoğlu İH, Haberal M Tags: Exp Clin Transplant Source Type: research

Antifibrotic Effects of Decellularized and Lyophilized Human Amniotic Membrane Transplant on the Formation of Intrauterine Adhesion.
Abstract OBJECTIVES: Intrauterine adhesion is a disease involving endometrial fibrosis that arises from injury to the basal layer of the endometrium. Here, we aimed to explore the preventive effects of decellularized and lyophilized amniotic membrane on endometrial fibrosis in a rat model of intrauterine adhesion. MATERIALS AND METHODS: Twenty-four Sprague-Dawley rats were randomly divided into 2 groups. For the intrauterine adhesion group, endometria of left uteri were scraped without treatment. For the intrauterine adhesion plus decellularized and lyophilized amniotic membrane transplant group, decellulariz...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Chen X, Sun J, Li X, Mao L, Zhou Y, Cui L, Bai W Tags: Exp Clin Transplant Source Type: research

The "UW-LPHS Test": A New Test to Predict the Outcome of Renal Autotransplant for Loin Pain Hematuria Syndrome.
CONCLUSIONS: The UW-LPHS test can be used to predict renal autotransplant outcomes and should be applied to all patients who are being considered for this operation. PMID: 30251941 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Sollinger HW, Al-Qaoud T, Bath N, Redfield RR Tags: Exp Clin Transplant Source Type: research

Retrograde Intrarenal Surgery Through an Incision of the Ureter as a Good Treatment Option for Large Ureteropelvic Impacted Stones in Transplanted Kidneys.
Abstract Urolithiasis is a rare complication after kidney transplant. Over the years, treatment of kidney stones has evolved radically, but a standard approach for transplanted kidneys has not yet been defined. Here, we present a 69-year-old male patient who received successful treatment of nephrolithiasis of the transplanted kidney. The patient, who had received a kidney from a deceased donor, was admitted to our department following a posttransplant Doppler ultrasonography showing severe hydronephrosis of the transplanted kidney associated with acute renal function decay. Computed tomography scan confirmed the h...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Ietto G, Saredi G, Soldini G, Iovino D, Amico F, Zani E, Berti L, Tozzi M, Carcano G Tags: Exp Clin Transplant Source Type: research

Intraoperative Tissue-Immunosuppressive Therapy Reduces Rejection Episodes in Heart Transplant Recipients.
Abstract OBJECTIVES: Our study was conducted to determine the effects of intraoperative antithymocyte globulin administration on donor hearts procured after cardiocirculatory death. We evaluated the impact of antithymocyte globulin on graft function and related parameters during isothermic blood cardioplegia. MATERIALS AND METHODS: In this prospective and randomized single center study, 30 patients with orthotropic heart transplant were divided into 2 groups: group 1 included 15 patients who received retrograde antithymocyte globulin infusion via coronary sinus intraoperatively and immediately after organ pro...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Rabus MB, Cekmecelioglu D, Ata P, Salihi S, Selcuk E, Balkanay M Tags: Exp Clin Transplant Source Type: research

Impact of Guideline-Driven Approach in Follow-Up of Long-Term Complications After Allogeneic Hematopoietic Cell Transplant: Single Center Experience.
CONCLUSIONS: For long-term follow-up, detailed evaluations of body organs and systems are essential. Early recognition of the aforementioned complications could decrease mortality and morbidity. For patients to be monitored by transplant centers over many years, training and awareness should be provided to ensure adequate follow-up of patients. Based on our results, we believe that the long-term follow-up guidelines used in our clinic are applicable to others. PMID: 30251944 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Kaya AH, Namdaroğlu S, Kayıkcı Ö, Merdin A, Batgi H, İskender D, Dal MS, Kızıl Çakar M, Tekgunduz E, Altuntas F Tags: Exp Clin Transplant Source Type: research

Dental Student Knowledge and Willingness to Donate Corneas.
Abstract OBJECTIVES: Our aim was to assess the knowledge and willingness to donate corneas among undergraduate dental students in Hyderabad city, India. MATERIALS AND METHODS: We conducted a cross-sectional study among undergraduate dental students of Panineeya Institute of Dental Sciences (Hyderabad, India). A pretested questionnaire was used to obtain information on demographic details, knowledge of cornea donation (7 questions), and willingness to donate corneas (3 questions). For analyses, we used chi-square and multivariate modeling tests. P
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 25, 2018 Category: Transplant Surgery Authors: Mahajan SV, Doshi D, Srilatha A, Karunakar P Tags: Exp Clin Transplant Source Type: research

Dolichoectasia Presenting as Renal Artery Aneurysm in a Deceased Donor Kidney: A Case Report and Review of the Literature.
We describe a case of fusiform aneurysm of the renal artery on a background of dolichoectasia in a kidney recovered from a deceased donor. The donor, a 57-year-old female, had died of an extensive nonsurvivable subarachnoid hemorrhage. Fusiform aneurysms involving the main renal artery and its superior branch had extended into the hilum with insufficient accessible stump for safe reconstruction. Placement of a stent through an intraoperative radiologic intervention was not possible without compromising renal perfusion. Consequently, renal transplant did not proceed. Dolichoectasia is a condition associated with generalized...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 4, 2018 Category: Transplant Surgery Authors: Silva ANS, Tahir W, Ahmad N Tags: Exp Clin Transplant Source Type: research

Otorhinolaryngologic Problems in Liver and Kidney Transplant Recipients.
CONCLUSIONS: A diverse variety of otorhinolaryngologic conditions, including emergencies and potentially life-threatening infections, were seen in our kidney and liver transplant recipients, both during the early and the late follow-up period. All transplant team members should be familiar with the clinical presentation of frequently seen otorhinolaryngologic diseases. PMID: 30198839 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 4, 2018 Category: Transplant Surgery Authors: Hizal E, Akdur A, Buyuklu F, Ozluoglu LN, Haberal M Tags: Exp Clin Transplant Source Type: research

Pilot Conversion Study From Mycophenolate Mofetil to Everolimus in Stable ABO-Incompatible Kidney Transplant Recipients: Analysis of 1-Year Follow-Up Data.
CONCLUSIONS: Everolimus elicited no acute rejection and no C4d deposition, whether everolimus was maintained or stopped within 1 year after conversion, in ABO-incompatible kidney transplant recipients. PMID: 30198840 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 4, 2018 Category: Transplant Surgery Authors: Uchida J, Iwai T, Nishide S, Kabei K, Kuwabara N, Naganuma T, Kumada N, Takemoto Y, Nakatani T Tags: Exp Clin Transplant Source Type: research

Individual Histologic Lesions and Composite Scores in Implant Biopsies Affect Short-Term and Long-Term Kidney Allograft Function.
CONCLUSIONS: Intraoperative biopsies are important in identifying patients at risk for worse graft function, especially concerning absence of gain of function early after transplant and loss of function late after transplant. PMID: 30119615 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 17, 2018 Category: Transplant Surgery Authors: Trailin AV, Nykonenko TN, Ostapenko TI, Vildanov SR, Nykonenko OS Tags: Exp Clin Transplant Source Type: research

Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant.
JF Abstract Heat stroke is a multiple organ dysfunction syndrome of poorly understood pathogenesis. Exertional heat stroke with acute liver failure is a rarely reported condition. Liver transplant has been recommended as treatment in cases of severe liver dysfunction; however, there are only 5 described cases of long-term survival after this procedure in patients with heat stroke. Here, we present 2 cases of young athletes who developed heat stroke. Both patients developed acute liver failure and were listed for liver transplant. Liver function tests of one patient improved, and he was discharged on postoperative...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 17, 2018 Category: Transplant Surgery Authors: Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF Tags: Exp Clin Transplant Source Type: research

Posttransplant Malignancies in Adult Renal and Hepatic Transplant Patients.
CONCLUSIONS: Despite recent positive developments in the use of immunosuppressive drugs, posttransplant malignancy is still a health problem. Fortunately, most cancers in this patient group have good prognosis and can be cured by surgical resection. Transplant physicians should aim for early detection of these diseases. PMID: 30119617 [PubMed - as supplied by publisher] (Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation)
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 17, 2018 Category: Transplant Surgery Authors: Rahatli S, Altundag O, Ayvazoglu Soy E, Moray G, Haberal M Tags: Exp Clin Transplant Source Type: research

Single-Center Experience With Liver Transplant Using Donors With Very High Transaminase Levels.
h A Abstract OBJECTIVES: Elevation of transaminases has been used as a marker of hepatic ischemic injury and as a crucial parameter for liver graft assessment. However, analysis of serum transaminases has limitations regarding the quantitative assessment of liver necrosis and is not a reliable predictor of outcomes. MATERIALS AND METHODS: We retrospectively reviewed the medical records of all liver transplants (N = 238) performed at the UMass Memorial Medical Center from 2009 to 2013. RESULTS: Fourteen liver grafts showed high peak aminotransferases alanine aminotransferase (ALT) and aspartate aminotrans...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 17, 2018 Category: Transplant Surgery Authors: Martins PN, Rawson A, Movahedi B, Brüggenwirth IMA, Dolgin NH, Martins AB, Mahboub P, Bozorgzadeh A Tags: Exp Clin Transplant Source Type: research

Prevalence of Incidental Findings on Multidetector Computed Tomography in Potential Nephrectomy Donors: A Prospective Observational Study.
in MM Abstract OBJECTIVES: Prospective renal donors are a select population of healthy individuals who have been thoroughly screened for significant comorbidities before they undergo multidetector computed tomography. Our aim was to determine the prevalence of incidental findings on preoperative multidetector computed tomography in a healthy cohort of potential living donors for kidney transplant. MATERIALS AND METHODS: A prospective study was performed of prospective living kidney transplant donors at a national kidney transplant center. Study inclusion criteria were all potential kidney donors who underwent...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 17, 2018 Category: Transplant Surgery Authors: O'Neill DC, Davis NF, Murray TÉ, Lee MJ, Little D, Morrin MM Tags: Exp Clin Transplant Source Type: research