Assessment of CT angiographic findings in comparison with echocardiography findings of chest among patients with aortic arch anomalies.
This study is a retrospective study based on the CT angiographic findings in comparison with transthoracic echocardiography findings of chest among patients with aortic arch anomalies. In this study, 203 patients with congenital anomalies were enrolled in the study, among those, 107 patients were men and 96 were female. The most common anomaly of the aortic arch was found to be coarctation (19.7%), followed by right sided arch with mirror image branching (19.2%). Furthermore, the most common cardiac anomalies associated with aortic arch anomalies were VSD, PA and PDA. The sensitivity and specificity of transthoracic echoca...
Source: Monaldi Archives for Chest Disease - October 3, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Wellens' syndrome: a case report with atypical features.
We describe a patient who presented at our emergency department with intermittent chest pain and showing Wellens' pattern T-wave inversions in the precordial leads of the electrocardiogram. She was found to have 95% stenosis in mid LAD. PMID: 31564087 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - October 2, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Secondary cardiovascular prevention in clinical practice: what do we need today?
Authors: Mureddu GF Abstract In the last decades, the post-hospital mortality from coronary artery disease (CAD) has significantly increased. This new trend in the epidemiology of CAD has been largely attributed to the improvement of survival from acute coronary syndromes that generated increasing incidence of population at high risk of recurrences and rehospitalization for major adverse cardiovascular events (MACE) and heart failure (HF). Thus, much longer after the acute event than we had thought, we have now been facing with higher complexity of "chronic" CAD phenotypes which deserve high clinical atte...
Source: Monaldi Archives for Chest Disease - October 2, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Pancreatic pleural effusion masquerading as right sided tubercular pleural effusion.
Authors: Chawla G, Niwas R, Chauhan NK, Dutt N, Yadav T, Jain P Abstract Pleural effusion is easily diagnosed often managed optimally with standard protocols. It at times, is a diagnostic dilemma as it comes with big list of differential diagnosis. Pleural effusion due to pancreaticopleural fistula (PPF) is a rare and on right side is even rarer. Detailed history along with high index of suspicion in required to diagnose PPF, which is confirmed by increased level of pleural fluid amylase and lipase along with magnetic resonance cholangiopancreatography (MRCP) or endoscopic retrograde cholangiopancreatography (ERCP)...
Source: Monaldi Archives for Chest Disease - September 29, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Comments on "Review of the association between periodontitis and chronic obstructive pulmonary disease in smokers".
Comments on "Review of the association between periodontitis and chronic obstructive pulmonary disease in smokers". Monaldi Arch Chest Dis. 2019 Sep 27;89(3): Authors: Pedron IG Abstract Comments on "Review of the association between periodontitis and chronic obstructive pulmonary disease in smokers" by Agathi Spiropoulou and colleagues, published in issue 1 of the 89th volume (2019) of the Monaldi Archives for Chest Disease. PMID: 31558005 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 29, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Similar outcome of heart failure with reduced EF patients with and without atrial fibrillation: considerations from the ESC Heart Failure Long-Term Registry.
Authors: De Vecchis R Abstract Recently, transcatheter ablation of atrial fibrillation (AF) has been validated by international societal guidelines as a technique suitable for both treatment and secondary prevention of paroxysmal, persistent or long-lasting persistent AF in highly symptomatic patients in whom at least one antiarrhythmic drug had been tested. PMID: 31505912 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Diastolic dysfunction in rheumatoid arthritis: a usual travel-mate?
Authors: Cavazzana I, Vizzardi E, Franceschini F Abstract A high rate of left ventricular diastolic dysfunction (LVDD) has been described in rheumatoid arthritis (RA), compared with general population. A prospective study demonstrated that LVDD occurred in 24% in one year of follow-up in RA patients without cardiac disease. Older age, higher systolic arterial pressure and lower E/A ratio are considered predictive factors. In addition, in RA, LVDD is known to be the only risk factor for the development of cardiovascular (CV) events, also in absence of classical CV risk factors. Some occasional reports suggest that e...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

The phyllotaxis of the aortic valve.
Authors: Moscarelli M, De Paulis R Abstract Biological systems ubiquitously and inevitably exhibit stochasticity in traits from the molecular level to the multicellular and morphological level. However, there are several examples of natural events that might be described in mathematical terms. Plants grow in a structured and geometric way to maximize their sun exposure for photosynthesis while reducing the stress. The 'Fibonacci sequence' and its 'golden ratio' are considered a mathematical regularity and model that is one of the corner-stone of the 'phyllotaxis', the part of the botany that studies how plants bran...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Incidence and predictors of new onset left ventricular diastolic dysfunction in asymptomatic patients with rheumatoid arthritis without overt cardiac disease.
In this study we assessed the incidence and the predictors of new-onset LVDD in RA patients. Two-hundred-ninety-five adults with RA without overt cardiac disease were prospectively analyzed from March 2014 to March 2015 by Doppler echocardiography. Among the 295 subjects evaluated, 217 (73.6%) had normal LV diastolic function and represented the final study population. At 1-year follow-up, 53 of 217 patients (24%) developed LVDD, which was of degree I (mild dysfunction) in all of them. By multivariate logistic regression analysis, lower E/A ratio of transmitral flow (ratio between the peak velocity of early diastolic "...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Radial pseudoaneurysm in elderly: a rare event with undefinied therapeutical approach. A case report and literature review.
In this report we describe the unique case of an 84-year-old female patient who developed radial artery pseudoaneurysm after a failed radial artery access for cardiac catheterization. Finally, the pseudoaneurysm was successfully treated by surgical approach as several attempts of local compression failed. We aimed also at reviewing the treatment options of RAP in elderly patients (>75 years old) and the safety/effectiveness reported in literature. PMID: 31505916 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Chewing ability and desaturation during chewing in patients with COPD.
Authors: Terashima T, Nakajima T, Matsuzaki T, Iwami E, Shibui T, Nomura T, Katakura A Abstract Chewing ability is essential to maintain nutrition status and can be associated with oral conditions, sarcopenia, and lung function in patients with chronic obstructive pulmonary disease (COPD). Herein, our pilot study investigated the chewing ability and degree of desaturation during chewing in patients with COPD (n = 41) and control subjects (n = 22). Subjects chewed a color-changing chewing gum for 1 minute and chewing ability was assessed by the color of the chewed gum, which was scored from 1 (very poor) to 5 (very ...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Statistical approach to mediastinal staging in NSCLC with M.E.S.S.i.a. software.
Authors: Galasso T, Corbetta L, Mancino L, Michieletto L, Ceron L Abstract The exclusion of pathological involvement of mediastinal lymph nodes in patients affected by NSCLC plays a central role in assessing  their prognosis and operability. Ceron et al. developed a software - called M.E.S.S.i.a (Mediastinal Evaluation with Statistical Support; instan approach) - that allows the calculation of the residual probability of lymph node involvement after a certain number of tests has been done, by integrating every test result with the pre-test prevalence. M.E.S.S.i.a. bridges a gap of current American College of C...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Anxiety and depression in adolescents with asthma and in their parents: a study in clinical practice.
The objective of this study was to investigate anxiety and depression in asthmatic adolescents and in their parents in a real-life setting. A series of adolescents with allergic asthma were consecutively enrolled. Asthma was diagnosed according to the GINA document and consistently the symptom control grade was assessed. We used the HADS questionnaire for the adolescents, and HADS, STAY, and BDI questionnaires for their parents. Globally, 121 adolescents (71 males, 50 females, mean age 13.4±0.8 years, age ranging between 12 and 15 years) with allergic asthma and their parents were evaluated. Only 29% of adolescents ...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Microscopic polyangiitis in a case of silica exposure: a rare presentation.
Authors: Gupta N, Mahendran AJ, Chakrabarti S, Agrawal S Abstract A 28-year-old male was admitted for breathlessness, haemoptysis, fever and fatigue. The patient had occupational exposure to silica dust. Arterial blood gas test ABG revealed hypoxemic respiratory failure. Chest CT demonstrated ground glass opacities with interlobular septal thickening and small centrilobular nodules with patchy areas of consolidation in bilateral lungs. He was mechanically ventilated for refractory hypoxemia. The treatment with cyclophosphamide and methylprednisolone lead to recovery and extubation. The final diagnosis was diffuse a...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Probe-based confocal laser endomicroscopy in diagnosis of desquamative interstitial pneumonia in nonsmoker.
Authors: Mamenko IS, Vasilev IV, Tabanakova IA, Gasanmagomedov SM, Sysoeva VV, Ushkov AD, Novickaya TA, Yablonskii PK Abstract Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways and alveoli. We use this method for desquamative interstitial pneumonia in nonsmoker. The pCLE image shows thickened intra-alveolar septae and clusters of autofluorescent cells within the alveoli...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Incidental diagnosis and therapeutic approach of an iatrogenic intra-parenchymal pulmonary intercostal artery pseudoaneurysm: a case report.
We report an unusual case of a late intercostal artery pseudoaneurysm, after a video-assisted thoracoscopic surgery, presenting as a large intra-parenchymal lung mass. Diagnosis was made by biphasic computed tomography angiography and contrast-enhanced pulsed-wave doppler ultrasound. To minimize the risk of aneurysm bleeding immediate angiographic embolization was planned and successfully performed.IAP should be considered in presence of lung mass in patients who have previously undergone an intervention with intercostal approach to prevent life-threatening complications. PMID: 31505922 [PubMed - in process] (Source: M...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Immune reconstitution inflammatory syndrome in tuberculous pleurisy and ulcerative colitis: a case report.
We present the case of a 46-year-old Caucasian male, affected by ulcerative colitis, who developed tuberculous pleurisy during immunosuppressive therapy; despite proper therapy, worsening of the radiological findings was observed. The case was discussed among an online group of Italian physicians and diagnosis of immune reconstitution inflammatory syndrome (IRIS) tuberculosis was established. Therapy was continued and full recovery was obtained. IRIS is a syndrome initially described during opportunistic infections in HIV infected after being placed in anti-retroviral therapy. It reveals itself through a wide variety of ma...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Carpal tunnel syndrome associated with sarcoidosis in identical twin patients.
We present two identical twin sarcoidosis patients with carpal tunnel syndrome. A number of factors may cause carpal tunnel syndrome like wrist anatomy, occupation, diabetes, rheumatoid arthritis, pregnancy and renal failure. Although the above factors do not directly cause carpal tunnel syndrome, they may increase your chances of developing or aggravate median nerve damage as it is in sarcoidosis. Sarcoidosis relevant neuropathy and granulomas may be the primary mechanism of sarcoidosis associated carpal tunnel syndrome. Although rare, carpal tunnel syndrome may be a feature of sarcoidosis that may lead to irreversib...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Depression and heart failure: an intricate relationship.
Authors: Aloisi G, Zucchelli A, Aloisi B, Romanelli G, Marengoni A Abstract In patients with heart failure (HF), depression is common and associated with adverse outcomes such as reduced adherence to treatment, poor quality of life, increased hospitalizations and elevated mortality. Despite these adverse impacts, depression remain underdiagnosed in HF patients. We performed a target review of the literature to identify the association between HF and depression, to examine the mechanisms that link these two conditions and to identify instruments for an accurate diagnosis and treatment of depression in HF patients. D...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Organizing pneumonia secondary to cetuximab in a patient with colorectal cancer.
Authors: AlGhulayqah A, AlShamsan B, Bazarbashi S, Mohammed S, Mobeireek A Abstract Organizing pneumonia (OP) may be idiopathic or secondary to a variety of causes including drugs. OP and other forms of pulmonary toxicity secondary to cetuximab, however, have been described rarely. It is paramount to recognize and differentiate OP from other common conditions that cancer patients are prone to such as infection and pulmonary embolism. A 69-year-old man with colorectal cancer received ten cycles of palliative chemotherapy [FOLFIRI (5-Fluorouracil, Leucovorin, Irinotecan) and cetuximab] with clinical and radiological ...
Source: Monaldi Archives for Chest Disease - September 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Similar predictive value of six-minute walking distance and B-type natriuretic peptide in heart failure with reduced to mid-range ejection fraction.
Authors: Scardovi AB, De Maria R, Galeotti GG, Faggiano P, Arcari L, Ghio S, Temporelli PL, Rossi A, Magni G, Simioniuc A, Ricci R, Dini FL Abstract The prognostic insights of heart failure (HF) with mid-range (40-49%) ejection fraction (HFmrEF) are not fully elucidated. We investigated whether the six-minutes walking test (6MWT) and brain natriuretic peptide (BNP) are predictive of outcome across the spectrum of LV systolic dysfunction and whether the HFmrEF cut-off impacts the risk stratification abilities of these tests. We studied 538 outpatients, aged 70±12 years, 28% females, with stable chronic HF and EF
Source: Monaldi Archives for Chest Disease - July 20, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Aortic root and valve proportions: an example of the golden ratio?
This study examined gated cardiac CT scans to make observations regarding the size and proportions of the valve leaflets, sinuses of Valsalva, and sinotubular junction. One hundred and fifty gated cardiac CT scans were performed for a variety of clinical indications. Area of each cusp (short axis plane) was measured along with sinus height (from leaflet base to sinotubular junction), sinus width (from central coaptation point to outer sinus edge), annular perimeter, perimeter at mid-sinus level, and perimeter at the sinotubular junction. The right coronary cusp was largest, the left cusp smallest, and the non-coronary cusp...
Source: Monaldi Archives for Chest Disease - July 20, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Treatment of EGFR positive lung adenocarcinoma in a heart transplanted patient.
We present case of a 65-year-old ex-smoker male with history of heart transplantation and EGFR positive metastatic lung adenocarcinoma. At admission he was in a severe clinical condition and treatment with erlotinib was started. Initially he had good clinical and radiologic response to treatment with only grade 1 side effects.  Data about drug interactions between cyclosporine and erlotinib are insufficient but we have to take this interaction into consideration during treatment because both drugs are substrates and inhibitors of CYP34A. In our case erlotinib was safe and well tolerated drug, there were no relevant to...
Source: Monaldi Archives for Chest Disease - July 20, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Monaldi Archives for Chest Disease - Cardiology Area: An essential instrument for the Italian Association of Cardiac Prevention and Rehabilitation (GICR-IACPR).
Authors: Cardiology Area TE Abstract At the beginning of the triennium 2019-2022, as Editors of the Monaldi Archives for Chest Disease - Cardiology Area, we  would like to share with all cardiologists and allied health  professionals working in cardiovascular prevention and  rehabilitation the status of our Journal, which is the official Journal of the Italian Association of Cardiac Prevention and Rehabilitation (GICR-IACPR), and has contributed in these past years, thanks to effort and dedication of all Editors who have preceded us, to the advancement of our profession, and to an enrichment and diss...
Source: Monaldi Archives for Chest Disease - July 20, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Extended dual antiplatelet therapy after acute myocardial infarction. Current evidence and future perspectives.
Authors: Cosentino N, Campodonico J, Milazzo V, Celentano K, Moltrasio M, Faggiano P, Marenzi G Abstract Patients with acute myocardial infarction (AMI) are at increased risk of recurrent ischemic events after hospital discharge, despite optimal medical therapy. Current practice guidelines strongly encourage the early assessment of the residual ischemic risk in post-AMI patients, in order to identify those who may benefit from a prolonged dual antiplatelet therapy. To this end, some scoring systems have been proposed. However, most scores were developed for patients with stable coronary artery disease undergoing pe...
Source: Monaldi Archives for Chest Disease - July 11, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Splenic artery aneurysm in Sj ögren's syndrome.
Splenic artery aneurysm in Sjögren's syndrome. Monaldi Arch Chest Dis. 2019 Jul 08;89(2): Authors: Tetikkurt C, Ozseker ZF, Karakaş FG Abstract A 40-year-old female presented with cough, exertional dyspnea, abdominal pain with distention, fatigue, dry eyes and dry mouth. Past history revealed asthma. Physical examination was normal except for tachypnea. We found leukocytosis, azygos fissure on chest X-ray along with normal pulmonary function tests and arterial blood gases.  Thorax computed tomography (CT) revealed bronchiectasis and ground glass opacities in both lungs. Abdominal CT demonstr...
Source: Monaldi Archives for Chest Disease - July 11, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Choosing Wisely, the reasons for its success.
Authors: Bobbio M, Vernero S Abstract The philosophy and the history of the International Choosing Wisely movement, launched in the U.S. in 2012, are described. It grew and spread beyond what it was anticipated at the beginning because there is a rising concern of the medical community regarding the appropriate use of procedures and treatments placed into the market before an adequate evaluation of risks and benefits. Not only healthcare providers, but also patients, citizens and politicians, are becoming aware of the consequences of inappropriate decisions and behaviors since inappropriateness has economic (w...
Source: Monaldi Archives for Chest Disease - June 15, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Diagnostic utility of PET/CT in a patient with miliary tuberculosis.
Authors: Tetikkurt C, Inci N, Yanardag H Abstract A 63-year-old male presented with loss of appetite, subfebrile fever, swelling of the right hand and dyspnea on exertion for three months. Past medical history revealed methotrexate treatment of six months for rheumatoid arthritis. Chest radiography and computed tomography (CT) revealed diffuse miliary nodules. PET/CT scan demonstrated diffuse FDG uptake in both lungs, in the spleen, in the right hand, the mediastinal and the axillary lymph nodes. MR of the right hand showed inflammatory arthritis. Histopathology of the right hand tru-cut biopsy revealed degenerativ...
Source: Monaldi Archives for Chest Disease - June 13, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Acute fibrinous organizing pneumonia: a rare lung pathology.
Authors: Kumar S, Mishra M, Goyal K, Bhatt R, Joshi P, Bansal S Abstract Acute fibrinous organizing pneumonia (AFOP) is a rare, non-infective lung pathology histologically characterized by patchy distribution of intra-alveolar fibrin "balls" and organizing pneumonia. It needs to be differentiated from other forms of acute pneumonia like community acquired pneumonia (CAP) because the treatment modalities are contrastingly different. Interesting case of a 45-year-old male initially suspected as a case of acute bacterial pneumonia but finally diagnosed as case of AFOP, is being reported. Initial empirical an...
Source: Monaldi Archives for Chest Disease - June 8, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

An uncommon cause of diffuse alveolar hemorrhage in a young male.
We report a case of a 16-year-old boy, who presented with hemoptysis and was eventually diagnosed as DAH with underlying SLE. Treatment with steroids and immunosuppressant helped in rapid recovery from this potentially life-threatening condition. This case highlights the need of defining diagnostic criteria for SLE in patients presenting as DAH and formulating guidelines for treatment of the same, especially in absence of co-existing lupus nephritis. PMID: 31170777 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - June 8, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Spontaneous hemothorax and neurofibromatosis type 1: How to explain it, how to explore it and how to treat it?
We reported two cases of patients with a history of von Recklinghausen's disease. Both of them suffered sudden chest pain. Chest-X ray revealed a hemi-thoracic opacity. Enhanced chest computed tomography showed massive hemothorax, but no evidence of tumors or an obvious bleeding point in the thorax. After we had ensured a stable hemodynamic condition, we performed video-assisted thoracic surgery to remove the hematoma. No evidence of bleeding was noticed in the first patient whereas an active bleeding was observed in the second patient. We could not determine which vessel was responsible of the hemorrhage. Electrocoagulati...
Source: Monaldi Archives for Chest Disease - June 6, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Metastatic cancer mimics interstitial lung disease. Cases when we need fast diagnosis and treatment.
Authors: Hecimovic A, Jakopovic M, Vukic Dugac A, Dzubur F, Samarzija M Abstract Interstitial lung diseases (ILD) are a heterogeneous group of diseases and one of the differential diagnosis which have to be excluded during diagnostic procedures are malignancies. We will present four patients who were referred to our Department because of suspicion of interstitial lung diseases according to radiology finding. In one case only, one of the radiologist's differential diagnosis was pulmonary lymphangitic carcinomatosis. All four patients had exertional dyspnea and dry cough which are nonspecific and can be first manifes...
Source: Monaldi Archives for Chest Disease - June 6, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

The complex interaction between atrial fibrillation and heart failure in elderly patients.
In conclusion, elderly patients simultaneously presenting problems of cardiac function and arrhythmia are an important challenge for geriatric medicine, and request important efforts to improve their functional profile and prognosis. PMID: 31162487 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - June 6, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Heart failure with preserved ejection fraction in elderly. From pathophysiology to treatment: an unresolved problem.
Authors: Beltrami M, Fumagalli C Abstract Heart failure with preserved ejection fraction (HFpEF) has a significant impact on healthcare resources and while its occurrence in the elderly is increasing, its prognosis has not improved. Despite the prevalence of HFpEF, the understanding of its pathophysiology is still incomplete, and optimal treatment remains largely undefined. The net clinical benefit of medical treatment with ACE inhibitors, ARBs, MRAs and beta-blockers has led to the incorporation of these drugs into HF clinical practice guidelines. However, little or no progress has been done for patients with...
Source: Monaldi Archives for Chest Disease - June 4, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Identification of subclinical cognitive impairment in chronic obstructive pulmonary disease using auditory P300 event related potential.
Authors: Krishnamurthy S, Sivagnaname Y, Gumallapu GC Abstract Adequate cognitive functioning in chronic obstructive pulmonary disease (COPD) patients is essential to understand the nature of the disease, adherence to treatment, and for leading a better quality of life. While cognitive impairment in severe forms of COPD have been well documented, identification of subclinical cognitive impairment in stable COPD patients remains crucial for planning prevention strategies. Hence the present study aimed to study and compare the cognitive function between the COPD patients, and normal individuals. The cognitive functio...
Source: Monaldi Archives for Chest Disease - June 4, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Postero-apical thoracic schwannoma with cervical extension resected by complete video-assisted thoracoscopic surgery.
We present two cases of cVATS resection of thoracic apical schwannomas. PMID: 31148605 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - June 4, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Educational level, marital status and sex as social gender discharge determinants in chronic obstructive pulmonary disease exacerbations: a time-to-event analysis.
Authors: Giannico OV, Ambrosino I, Patano F, Germinario C, Quarto M, Moretti AM Abstract The aim of this study is to evaluate, in patients hospitalized for COPD exacerbation, how educational level, marital status and sex (social gender indicators) affect the prognosis (main effects) and how interact with each other in affecting prognosis (effect modification). Data for all patients discharged with a principal diagnosis of COPD with exacerbation (ICD-9 491.21) by Apulian facilities between 2013 and 2017 were retrieved from the National Hospital Discharge Register Database. A multivariable multi-stratified frailty co...
Source: Monaldi Archives for Chest Disease - May 29, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Use of the North American Nursing Diagnosis Association taxonomies, Nursing Intervention Classification, Nursing Outcomes Classification and NANDA-NIC-NOC linkage in cardiac rehabilitation.
This study aims at creating a standardized language for each patient admitted to Cardiac Rehabilitation Unit (CR) by identifying nursing diagnosis, interventions, results/objectives expected and related correlations. The primary outcome was identifying health needs of all patients admitted to CR. The secondary outcomes were the identification of North American Nursing Diagnosis Association -International diagnoses (NANDA-I), of nursing intervention classification (NIC), of nursing outcomes classification (NOC) and their correlation NANDA-NIC-NOC linkage (NNN linkage) in order to define a standardized language for all nursi...
Source: Monaldi Archives for Chest Disease - May 29, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Choosing wisely in cardiology: Five proposals from the Italian Association for Cardiovascular Prevention and Rehabilitation.
Authors: Werren M, Copetti R, Gaibazzi N, Giada F, Faggiano A, Ricci C, Faggiano P Abstract We do not always accomplish what is best for our patients. Is "more procedures, more drugs" a real synonym of good and always useful medicine? Probably not. Indeed, it has been highlighted that many tests and treatments, widely used in medical practice, do not bring benefits to patients, but they can be harmful. So, why do we keep performing them? Many reasons, surely one of the main is the constant fear of malpractice legal-medical consequences; this led to the development of a defensive medicine, no longer focuse...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Invasive Aspergillus tracheobronchitis in a patient with hairy cell leukemia and previous Plasmodium falciparum infection.
Authors: Antonogiannaki EM, Proklou A, Tamiolakis D, Vassalou E, Kondili E Abstract Invasive Aspergillus tracheobronchitis is a relatively rare form of invasive pulmonary aspergillosis characterized by invasion of the tracheobronchial tree by Aspergillus spp. Invasive pulmonary aspergillosis is predominantly detected in severely immunocompromised patients. Notably however, pulmonary and tracheobronchial cases of invasive aspergillosis have also been reported, particularly in the context of severe malaria caused by Plasmodium falciparum. Herein, we present a case of invasive Aspergillus tracheobronchitis in a patien...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Mediastinal debulking for a T-cell leukaemia/lymphoma presenting with cardiac tamponade.
Authors: Moraitis SD, Agrafiotis AC, Marinos L, Panagiotou I, Sakellaridis T, Tsakalakis C, Poulakidas E Abstract Anterior mediastinal masses are relatively uncommon and include a wide variety of lesions. Lymphomas account for 25% of anterior mediastinal masses. Lymphomas and other haematological malignancies are associated with pericardial effusion. There are also cases where a cardiac tamponade occurred. The aim of the case reported herein is to discuss the surgical approach and particularly the mediastinal debulking as an adjunct to systematic treatment for haematological diseases presenting as an anterior media...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Secondary prevention advices after cardiovascular index event: From drug prescription to risk factors control in real world practice.
Authors: Faggiano P, Fattirolli F, Frisinghelli A, Piccioli L, Dasseni N, Silverii MV, Albricci L, D'Ambrosio G, Garrì R, Esposito L, Giallauria F Abstract The present study aims at evaluating the achievement of blood pressure, lipid and blood glucose targets, healthy lifestyle changes and appropriate drug prescription/adherence in patients attending secondary prevention/CR ambulatory visit after index cardiovascular event in a time period ranging 1 to 5 year. At ambulatory visit, a predetermined set of data collection was used, including demographic data, cardiovascular risk factors and lifestyle habits, ty...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Macro- and microvascular functions in cystic fibrosis adults without cardiovascular risk factors: A case-control study.
Authors: Vizzardi E, Sciatti E, Bonadei I, Cani DS, Menotti E, Prati F, Dallapellegrina L, Metra M, Berlendis M, Poli P, Padoan R Abstract Increasing survival from cystic fibrosis show untypical systems involvement, such as cardiocirculatory. In particular, the presence of CFTR in smooth muscle and endothelial cells, systemic inflammation and oxidative stress could explain vascular alterations in these patients. We aimed at noninvasely evaluating macro- and microvascular dysfunction in cystic fibrosis adults without cardiovascular risk factors. Twenty-twoadults affected by cystic fibrosis and 24 healthy volunteers ...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A retrospective study of endobronchial ultrasound transbronchial needle aspiration versus conventional transbronchial needle aspiration in diagnosis/staging of hilar/mediastinal lymph node in lung cancer: Which role in clinical practice?
Authors: Conte SC, Spagnol G, Biolo M, Confalonieri M Abstract The conventional-trans bronchial needle aspiration (c-TBNA) has been the first procedure for sampling hilar/mediastinal lymph node for the diagnosis/staging of lung cancer. In the last decade the endobronchial ultrasound trans bronchial needle aspiration (EBUS-TBNA) was introduced in clinical practice and became the first-choice exam in diagnosis and staging of lung cancer. The aim of this study was to compare the diagnostic accuracy (DA), sensitivity and adequacy of c-TBNA and EBUS-TBNA. It was a retrospective and observational multicenter study. The f...
Source: Monaldi Archives for Chest Disease - April 19, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Dietary advice to cardiovascular patients. A brief update for physicians.
Authors: Visioli F, Poli A Abstract It is important, in our opinion, to provide physicians with a brief update of scientifically-sound evidence in preventive nutrition, to be employed in their everyday practice, since the latest scientific and clinical advances in this area are generally not well known. Here, we review the most recent evidence in support of an optimal cardio-protective diet, and we identify the need to focus mainly on protective food which should be part of such diet, rather than on nutrients with negative effects to be limited (salt, saturated fats, simple sugars). We conclude that, to favor patie...
Source: Monaldi Archives for Chest Disease - April 17, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Heart failure in the elderly: A geriatric syndrome. Picture of the modern situation.
Authors: Fagotto V, Cavarape A, Boccanelli A Abstract Among the older patients' cohort, the aetiology of heart failure is peculiar and differs in many ways from the younger one, both in its epidemiology, diagnostic work-up and clinical presentation. Focusing on this population, we could assume that heart failure is a real geriatric syndrome, characterized by several features, which coexist with other comorbidities and require specific and targeted cares. It is therefore necessary to examine the global burden of heart failure and the patient's history rather than the causal cardiomyopathy - frequently more than one ...
Source: Monaldi Archives for Chest Disease - April 17, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Role and efficacy of cardiac rehabilitation in patients with heart failure.
Authors: La Rovere MT, Traversi E Abstract Despite improvements in treatments, the prognosis of heart failure remains poor. Elderly patients with heart failure are burdened with multiple co-morbidities and polypharmacy. Multidisciplinary disease-management programs are recommended as standard care for patients at high risk of hospitalization. Cardiac rehabilitation is defined a coordinated multidimensional intervention that integrates the basic elements in multidisciplinary management programs with a continuing program of physical activity and exercise training. Cardiac rehabilitation services can be provided on an...
Source: Monaldi Archives for Chest Disease - April 17, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Accomplishments, engagements and new challenges for the Monaldi Archives for Chest Disease.
Authors: Editors T Abstract The Editors: Antonio Spanevello, Bruno Balbi Another year has passed, and we would like to thank and recognize all of the many members who have contributed to the editorial process and content of Monaldi during 2018. Our submissions are increasing, citations for our papers are rising, and recognition of the journal is broadening. Not settled for focusing on past goings-on only, we now direct our efforts toward building an even greater impact. PMID: 30968652 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 12, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Arrhythmogenic right ventricular cardiomyopathy or athlete's heart? Challenges in assessment of right heart morphology and function.
Authors: Antonini-Canterin F, Di Nora C Abstract The incidence of sudden cardiac death (SCD) in young athletes varies among studies, due to the disagreement in the definitions and the lack of information in this field. PMID: 30968653 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 12, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Early mobilization in LVAD recipients: An obligatory step towards recovery.
Authors: Corrà U, Pistono M Abstract Chronic heart failure (CHF) is a devastating clinical syndrome. Therapeutic schemes have developed rapidly from conventional medical therapy to biomedical strategies, interventional, mechanical, that incorporates left ventricular assistant device (LVAD), surgical, regenerate, and rehabilitating policies. These therapies have improved the symptoms and life expectancy. PMID: 30968654 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 12, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research