Clinico-radiological profile of connective tissue disease related-interstitial lung diseases from a tertiary care centre of India: a cross sectional study
Monaldi Arch Chest Dis. 2021 Apr 2. doi: 10.4081/monaldi.2021.1624. Online ahead of print.ABSTRACTInterstitial lung diseases (ILDs) are a frequently occurring pulmonary manifestation in patients of connective tissue diseases (CTD). Detailed understanding of this subset of lung diseases is vital, hence the study was conducted to analyze the clinico-radiological characteristics of CTD-ILD. The present study was conducted between March 2017 to February 2018 at a tertiary care teaching hospital from western India. A total of 100 patients having respiratory symptoms suggestive of ILD, who were either diagnosed cases of CTD or h...
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Mehul Agarwal Manohar Lal Gupta Kunal Deokar Benhur Joel Shadrach Neha Bharti Maldev Sonigra Source Type: research

The Maugeri daily activity profile: a tool to assess physical activity in patients with chronic obstructive pulmonary disease
Monaldi Arch Chest Dis. 2021 Apr 2. doi: 10.4081/monaldi.2021.1680. Online ahead of print.ABSTRACTPatients with chronic obstructive pulmonary disease (COPD) report reduced physical activity (PA). There are only few tools available to assess PA and sedentary behavior in these patients, and none of them aims to differentiate between sedentary and active patterns. The aim of the study was to evaluate an easy tool to profile daily activity time in a cohort of patients with COPD, compared to healthy subjects; the study was set at the Istituti Clinici Scientifici Maugeri (ICS), IRCCS of Tradate and Lumezzane, Italy, and at the E...
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Elisabetta Zampogna Giorgio Bertolotti Nicolino Ambrosino Giuseppe Lo Bello Francesca Cherubino Alessandra Ianni Mara Paneroni Patrizia Pignatti Dina Visca Andrea Zanini Andrea Giordano Source Type: research

Recovering of oxygenation, physical function and disability in patients with COVID-19
Monaldi Arch Chest Dis. 2021 Apr 9. doi: 10.4081/monaldi.2021.1817. Online ahead of print.ABSTRACTThe present cases report describes middle-time course of respiratory and physical variables in eight COVID-19 patients who were transferred from ICU of COVID Hub in our subacute COVID-19 unit. Secondly, they were admitted in a pulmonary rehabilitation unit and, at discharge, a tele-rehabilitation program was provided as a continuum of care at home. Time course of oxygenation, physical function and disability were recorded. As expected, the acute event produced in these patients a dramatic worsening in oxygenation and physical ...
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Laura Bertacchini Mara Paneroni Laura Comini Simonetta Scalvini Michele Vitacca Source Type: research

Apparently normal epicardial coronaries in a patient with inferior wall myocardial infraction on the background of mild coronavirus disease-2019: take a second look!
Monaldi Arch Chest Dis. 2021 Apr 6. doi: 10.4081/monaldi.2021.1668. Online ahead of print.ABSTRACTThe coronary angiographic (CAG) findings of ST elevation myocardial infarction (STEMI) in patients of coronavirus disease 2019 (COVID-19) range from increased coronary artery thrombus burden to normal coronaries due to STEMI mimics. Here we report the case of a 45-year-old gentleman who presented with evolved inferior wall myocardial infarction with ongoing angina along with mild COVID-19. CAG showed normal epicardial coronaries except for distal right posterior descending coronary artery (RPDA) 100% occlusion on careful exami...
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Barun Kumar Ashwin Kodliwadmath Amar Upadhyay Anupam Singh Nanda N Source Type: research

Gender differences in vaccine therapy: where are we in COVID-19 pandemic?
In conclusion, it is apparent that the design of vaccines and vaccine strategies should be sex-specific, to reduce adverse reactions in females and increase immunogenicity in males. It should be mandatory to examine sex-related variables in pre-clinical and clinical vaccine trials, such as their crucial role for successful prevention of pandemic COVID-19.PMID:33840183 | DOI:10.4081/monaldi.2021.1669 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Tiziana Ciarambino Elena Barbagelata Graziamaria Corbi Immacolata Ambrosino Cecilia Politi Franco Lavalle Anna Ruggieri Annamaria Moretti Source Type: research

Assessment score for the diagnosis of a case with pleuroparenchymal fibroelastosis
Monaldi Arch Chest Dis. 2021 Apr 6. doi: 10.4081/monaldi.2021.1713. Online ahead of print.ABSTRACTIdiopathic pleuropulmonary fibroelastosis is an extremely rare lung disease characterized by the combination of fibrosis of the visceral pleura and the fibroelastotic changes transcending in the subpleural lung parenchyma that predominantly affects the upper lobes with accompanying volume loss. It is mostly idiopathic while infection, autoimmunity, bone marrow or lung transplantation and genetic predisposition may be associated with the development of PPFE. The disease is exceptionally rare as approximately ninety cases have b...
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Cuneyt Tetikkurt Bahar Kubat Cigdem Kulahci Seza Tetikkurt Buket Caliskaner Ozturk Source Type: research

Endocrinological abnormalities and Takotsubo cardiomyopathy
Monaldi Arch Chest Dis. 2021 Apr 12. doi: 10.4081/monaldi.2021.1859. Online ahead of print.ABSTRACTDear Editor, We read with much excitement in the article "Takotsubo syndrome and pheochromocytoma: an insidious combination" published by Maffé et al. in your esteemed journal...PMID:33840185 | DOI:10.4081/monaldi.2021.1859 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 12, 2021 Category: Respiratory Medicine Authors: Anu Anna George Kevin John John Vijairam Selvaraj Ajay Kumar Mishra Source Type: research

Recurrent tracheal tumor with a critical airway requiring 'Y' stent - unique presentation of tuberculosis
We report an extremely rare case of isolated paratracheal lymphadenitis due to tuberculosis, eroding the trachea and presented a lower tracheal tumor, which recurred again after complete debulking. Finally, the disease required a 'Y' stent placement, to stabilize the airway following the second recanalization. We discuss the incidence, differential diagnosis, and the bronchoscopic, interventional aspects of this entity.PMID:33794588 | DOI:10.4081/monaldi.2021.1578 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Venugopal Jaganathan Santhakumar Subramanian Deepak T Hari Source Type: research

Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1586. Online ahead of print.ABSTRACTInflammatory myofibroblastic tumors (IMT) are rare soft tissue tumors of intermediate malignant potential occurring usually in children and adolescents. Treatment options for advanced diseases are limited. A 35-year-old lady presented to us with fever, cough and decreased appetite. On evaluation, she was diagnosed with left lung IMT. She underwent surgery and developed recurrence with pleural nodules after two years. Immunohistochemistry showed positivity for ALK (diffuse). Since recent evidence suggested that crizotinib is e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Abhenil Mittal Aarushi Gupta Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Indirect comparison between ferric carboxymaltose and oral iron replacement in heart failure with reduced ejection fraction: a network meta-analysis
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1703. Online ahead of print.ABSTRACTTreatment of iron deficiency (ID) in patients with heart failure (HF) has improved symptoms, quality of life, exercise capacity and has reduced hospitalizations in randomized controlled trials (RCTs) and meta-analyses. Intravenous ferric carboxymaltose (FCM) provided convincing results in this field, while oral iron supplementation failed. However, FCM and oral iron were compared to placebo, and a comparison between the two strategies is still lacking. We aimed to fill this gap of knowledge with an indirect comparison between...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Edoardo Sciatti Ugo Nesti Andrea Di Lenarda Source Type: research

Continuous positive airway pressure therapy in the management of hypercapnic cardiogenic pulmonary edema
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1725. Online ahead of print.ABSTRACTContinuous positive airway pressure (CPAP) therapy or non-invasive ventilation (NIV) represent the first line therapy for acute cardiogenic pulmonary edema (CPE) together with medical therapy. CPAP benefits in acute CPE with normo-hypocapnia are known, but it is not clear whether the use of CPAP is safe in the hypercapnic patients. The aim of this study is to evaluate CPAP efficacy in the treatment of hypercapnic CPE. We enrolled 9 patients admitted to the emergency room with diagnosis of acute CPE based on history, clinical e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Alfonso Sforza Mario Guarino Claudia Sara Cimmino Arturo Izzo Giovanna Cristiano Costantino Mancusi Gerolamo Sibilio Maria Viviana Carlino Source Type: research

Bleeding events in COVID-19: the other side of the coin?
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the ant...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Antonietta Coppola Anna Annunziata Maria Rosaria Gioia Giuseppe Fiorentino Source Type: research

Post COVID-19 tuberculosis: An emerging threat of pandemic
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1749. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) pandemic has hit the world hard. Millions of people have died due to the infection and several have suffered with what are now known as post COVID-19 squeal. Among these squeals one is immunosuppression which leaves patients prone to severe opportunistic infection. We here report a case of young female who was infected by COVID-19 and later developed cavitary pneumonia which upon investigation turned out to be due to mycobacterium tuberculosis. Th...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Aqusa Zahid Nousheen Iqbal Sarosh Moeen Muhammad Irfan Source Type: research

Non-invasive ventilation in the elderly - never too late!
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1796. Online ahead of print.ABSTRACTDear Editor, Practising evidence-based medicine in an ageing population is challenging. Nevertheless, using age as a diagnostic or therapeutic procedure contraindication is less and less common. Domiciliary non-invasive ventilation (NIV) in chronic respiratory failure patients has been largely used; however, data from older people is scarce...PMID:33794594 | DOI:10.4081/monaldi.2021.1796 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Leonor Mendon ça Almeida Maria Jacob Mafalda Van Zeller Tiago Pinto Miguel Gon çalves Marta Drummond Source Type: research

The initial experience of COVID-19 vaccination from a tertiary care centre of India
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1816. Online ahead of print.ABSTRACTTo the Editor Drugs Controller General of India (DCGI) has approved the Bharat biotech vaccine against COVID-19, which is a locally manufactured inactivated vaccine named ''COVAXIN'' in collaboration with the Indian council of medical research (ICMR) on 3rd January 2021 for emergency use along with the "Covishield" Oxford-AstraZeneca vaccine manufactured locally by the Serum Institute of India... *The Safdarjung COVID-19 Vaccination group: KR Meena (Professor, Paediatrics), U Venkatesh (Assistant Professor, Communit...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: R K Srivastava Pranav Ish Safdarjung Covid-Vaccination Group Source Type: research

Imaging the COVID-19: a practical guide
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1630. Online ahead of print.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) represents the first medical catastrophe of the new millennium. Although imaging is not a screening test for COVID-19, it plays a crucial role in evaluation and follow-up of COVID-19 patients. In this paper, we will review typical and atypical imaging findings of COVID-19.PMID:33794596 | DOI:10.4081/monaldi.2021.1630 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Francesco Agnello Lidia Rabiolo Emanuele Grassedonio Patrizia Toia Federico Midiri Luigi Spatafora Francesco Matteini Lorenzo Tes è Ludovico La Grutta Massimo Galia Source Type: research

How to avoid "en masse" lobectomy using VATS technique in presence of hilar fibrosis
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1633. Online ahead of print.ABSTRACTPerivascular fibrosis is technically one of the most challenging issue to manage during thoracoscopic lobectomy and it is associated with increased risk of hemorrhagic injury. Here we report a case of thoracoscopic right lower lobectomy performed with individual dissection of segmental arteries due to dense adventitial fibrosis around the right lower lobe pulmonary artery. This approach may be considered as an alternative to the so-called "en masse" lobectomy and a way to avoid conversion to thoracotomy.PMID:3379459...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Dario Amore Dino Casazza Alessandro Saglia Pasquale Imitazione Umberto Caterino Carlo Curcio Source Type: research

Recurrent tracheal tumor with a critical airway requiring 'Y' stent - unique presentation of tuberculosis
We report an extremely rare case of isolated paratracheal lymphadenitis due to tuberculosis, eroding the trachea and presented a lower tracheal tumor, which recurred again after complete debulking. Finally, the disease required a 'Y' stent placement, to stabilize the airway following the second recanalization. We discuss the incidence, differential diagnosis, and the bronchoscopic, interventional aspects of this entity.PMID:33794588 | DOI:10.4081/monaldi.2021.1578 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Venugopal Jaganathan Santhakumar Subramanian Deepak T Hari Source Type: research

Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1586. Online ahead of print.ABSTRACTInflammatory myofibroblastic tumors (IMT) are rare soft tissue tumors of intermediate malignant potential occurring usually in children and adolescents. Treatment options for advanced diseases are limited. A 35-year-old lady presented to us with fever, cough and decreased appetite. On evaluation, she was diagnosed with left lung IMT. She underwent surgery and developed recurrence with pleural nodules after two years. Immunohistochemistry showed positivity for ALK (diffuse). Since recent evidence suggested that crizotinib is e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Abhenil Mittal Aarushi Gupta Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Indirect comparison between ferric carboxymaltose and oral iron replacement in heart failure with reduced ejection fraction: a network meta-analysis
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1703. Online ahead of print.ABSTRACTTreatment of iron deficiency (ID) in patients with heart failure (HF) has improved symptoms, quality of life, exercise capacity and has reduced hospitalizations in randomized controlled trials (RCTs) and meta-analyses. Intravenous ferric carboxymaltose (FCM) provided convincing results in this field, while oral iron supplementation failed. However, FCM and oral iron were compared to placebo, and a comparison between the two strategies is still lacking. We aimed to fill this gap of knowledge with an indirect comparison between...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Edoardo Sciatti Ugo Nesti Andrea Di Lenarda Source Type: research

Continuous positive airway pressure therapy in the management of hypercapnic cardiogenic pulmonary edema
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1725. Online ahead of print.ABSTRACTContinuous positive airway pressure (CPAP) therapy or non-invasive ventilation (NIV) represent the first line therapy for acute cardiogenic pulmonary edema (CPE) together with medical therapy. CPAP benefits in acute CPE with normo-hypocapnia are known, but it is not clear whether the use of CPAP is safe in the hypercapnic patients. The aim of this study is to evaluate CPAP efficacy in the treatment of hypercapnic CPE. We enrolled 9 patients admitted to the emergency room with diagnosis of acute CPE based on history, clinical e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Alfonso Sforza Mario Guarino Claudia Sara Cimmino Arturo Izzo Giovanna Cristiano Costantino Mancusi Gerolamo Sibilio Maria Viviana Carlino Source Type: research

Bleeding events in COVID-19: the other side of the coin?
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the ant...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Antonietta Coppola Anna Annunziata Maria Rosaria Gioia Giuseppe Fiorentino Source Type: research

Post COVID-19 tuberculosis: An emerging threat of pandemic
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1749. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) pandemic has hit the world hard. Millions of people have died due to the infection and several have suffered with what are now known as post COVID-19 squeal. Among these squeals one is immunosuppression which leaves patients prone to severe opportunistic infection. We here report a case of young female who was infected by COVID-19 and later developed cavitary pneumonia which upon investigation turned out to be due to mycobacterium tuberculosis. Th...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Aqusa Zahid Nousheen Iqbal Sarosh Moeen Muhammad Irfan Source Type: research

Non-invasive ventilation in the elderly - never too late!
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1796. Online ahead of print.ABSTRACTDear Editor, Practising evidence-based medicine in an ageing population is challenging. Nevertheless, using age as a diagnostic or therapeutic procedure contraindication is less and less common. Domiciliary non-invasive ventilation (NIV) in chronic respiratory failure patients has been largely used; however, data from older people is scarce...PMID:33794594 | DOI:10.4081/monaldi.2021.1796 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Leonor Mendon ça Almeida Maria Jacob Mafalda Van Zeller Tiago Pinto Miguel Gon çalves Marta Drummond Source Type: research

The initial experience of COVID-19 vaccination from a tertiary care centre of India
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1816. Online ahead of print.ABSTRACTTo the Editor Drugs Controller General of India (DCGI) has approved the Bharat biotech vaccine against COVID-19, which is a locally manufactured inactivated vaccine named ''COVAXIN'' in collaboration with the Indian council of medical research (ICMR) on 3rd January 2021 for emergency use along with the "Covishield" Oxford-AstraZeneca vaccine manufactured locally by the Serum Institute of India... *The Safdarjung COVID-19 Vaccination group: KR Meena (Professor, Paediatrics), U Venkatesh (Assistant Professor, Communit...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: R K Srivastava Pranav Ish Safdarjung Covid-Vaccination Group Source Type: research

Imaging the COVID-19: a practical guide
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1630. Online ahead of print.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) represents the first medical catastrophe of the new millennium. Although imaging is not a screening test for COVID-19, it plays a crucial role in evaluation and follow-up of COVID-19 patients. In this paper, we will review typical and atypical imaging findings of COVID-19.PMID:33794596 | DOI:10.4081/monaldi.2021.1630 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Francesco Agnello Lidia Rabiolo Emanuele Grassedonio Patrizia Toia Federico Midiri Luigi Spatafora Francesco Matteini Lorenzo Tes è Ludovico La Grutta Massimo Galia Source Type: research

How to avoid "en masse" lobectomy using VATS technique in presence of hilar fibrosis
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1633. Online ahead of print.ABSTRACTPerivascular fibrosis is technically one of the most challenging issue to manage during thoracoscopic lobectomy and it is associated with increased risk of hemorrhagic injury. Here we report a case of thoracoscopic right lower lobectomy performed with individual dissection of segmental arteries due to dense adventitial fibrosis around the right lower lobe pulmonary artery. This approach may be considered as an alternative to the so-called "en masse" lobectomy and a way to avoid conversion to thoracotomy.PMID:3379459...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Dario Amore Dino Casazza Alessandro Saglia Pasquale Imitazione Umberto Caterino Carlo Curcio Source Type: research

Recurrent tracheal tumor with a critical airway requiring 'Y' stent - unique presentation of tuberculosis
We report an extremely rare case of isolated paratracheal lymphadenitis due to tuberculosis, eroding the trachea and presented a lower tracheal tumor, which recurred again after complete debulking. Finally, the disease required a 'Y' stent placement, to stabilize the airway following the second recanalization. We discuss the incidence, differential diagnosis, and the bronchoscopic, interventional aspects of this entity.PMID:33794588 | DOI:10.4081/monaldi.2021.1578 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Venugopal Jaganathan Santhakumar Subramanian Deepak T Hari Source Type: research

Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1586. Online ahead of print.ABSTRACTInflammatory myofibroblastic tumors (IMT) are rare soft tissue tumors of intermediate malignant potential occurring usually in children and adolescents. Treatment options for advanced diseases are limited. A 35-year-old lady presented to us with fever, cough and decreased appetite. On evaluation, she was diagnosed with left lung IMT. She underwent surgery and developed recurrence with pleural nodules after two years. Immunohistochemistry showed positivity for ALK (diffuse). Since recent evidence suggested that crizotinib is e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Abhenil Mittal Aarushi Gupta Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Indirect comparison between ferric carboxymaltose and oral iron replacement in heart failure with reduced ejection fraction: a network meta-analysis
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1703. Online ahead of print.ABSTRACTTreatment of iron deficiency (ID) in patients with heart failure (HF) has improved symptoms, quality of life, exercise capacity and has reduced hospitalizations in randomized controlled trials (RCTs) and meta-analyses. Intravenous ferric carboxymaltose (FCM) provided convincing results in this field, while oral iron supplementation failed. However, FCM and oral iron were compared to placebo, and a comparison between the two strategies is still lacking. We aimed to fill this gap of knowledge with an indirect comparison between...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Edoardo Sciatti Ugo Nesti Andrea Di Lenarda Source Type: research

Continuous positive airway pressure therapy in the management of hypercapnic cardiogenic pulmonary edema
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1725. Online ahead of print.ABSTRACTContinuous positive airway pressure (CPAP) therapy or non-invasive ventilation (NIV) represent the first line therapy for acute cardiogenic pulmonary edema (CPE) together with medical therapy. CPAP benefits in acute CPE with normo-hypocapnia are known, but it is not clear whether the use of CPAP is safe in the hypercapnic patients. The aim of this study is to evaluate CPAP efficacy in the treatment of hypercapnic CPE. We enrolled 9 patients admitted to the emergency room with diagnosis of acute CPE based on history, clinical e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Alfonso Sforza Mario Guarino Claudia Sara Cimmino Arturo Izzo Giovanna Cristiano Costantino Mancusi Gerolamo Sibilio Maria Viviana Carlino Source Type: research

Bleeding events in COVID-19: the other side of the coin?
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the ant...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Antonietta Coppola Anna Annunziata Maria Rosaria Gioia Giuseppe Fiorentino Source Type: research

Post COVID-19 tuberculosis: An emerging threat of pandemic
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1749. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) pandemic has hit the world hard. Millions of people have died due to the infection and several have suffered with what are now known as post COVID-19 squeal. Among these squeals one is immunosuppression which leaves patients prone to severe opportunistic infection. We here report a case of young female who was infected by COVID-19 and later developed cavitary pneumonia which upon investigation turned out to be due to mycobacterium tuberculosis. Th...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Aqusa Zahid Nousheen Iqbal Sarosh Moeen Muhammad Irfan Source Type: research

Non-invasive ventilation in the elderly - never too late!
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1796. Online ahead of print.ABSTRACTDear Editor, Practising evidence-based medicine in an ageing population is challenging. Nevertheless, using age as a diagnostic or therapeutic procedure contraindication is less and less common. Domiciliary non-invasive ventilation (NIV) in chronic respiratory failure patients has been largely used; however, data from older people is scarce...PMID:33794594 | DOI:10.4081/monaldi.2021.1796 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Leonor Mendon ça Almeida Maria Jacob Mafalda Van Zeller Tiago Pinto Miguel Gon çalves Marta Drummond Source Type: research

The initial experience of COVID-19 vaccination from a tertiary care centre of India
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1816. Online ahead of print.ABSTRACTTo the Editor Drugs Controller General of India (DCGI) has approved the Bharat biotech vaccine against COVID-19, which is a locally manufactured inactivated vaccine named ''COVAXIN'' in collaboration with the Indian council of medical research (ICMR) on 3rd January 2021 for emergency use along with the "Covishield" Oxford-AstraZeneca vaccine manufactured locally by the Serum Institute of India... *The Safdarjung COVID-19 Vaccination group: KR Meena (Professor, Paediatrics), U Venkatesh (Assistant Professor, Communit...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: R K Srivastava Pranav Ish Safdarjung Covid-Vaccination Group Source Type: research

Imaging the COVID-19: a practical guide
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1630. Online ahead of print.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) represents the first medical catastrophe of the new millennium. Although imaging is not a screening test for COVID-19, it plays a crucial role in evaluation and follow-up of COVID-19 patients. In this paper, we will review typical and atypical imaging findings of COVID-19.PMID:33794596 | DOI:10.4081/monaldi.2021.1630 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Francesco Agnello Lidia Rabiolo Emanuele Grassedonio Patrizia Toia Federico Midiri Luigi Spatafora Francesco Matteini Lorenzo Tes è Ludovico La Grutta Massimo Galia Source Type: research

How to avoid "en masse" lobectomy using VATS technique in presence of hilar fibrosis
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1633. Online ahead of print.ABSTRACTPerivascular fibrosis is technically one of the most challenging issue to manage during thoracoscopic lobectomy and it is associated with increased risk of hemorrhagic injury. Here we report a case of thoracoscopic right lower lobectomy performed with individual dissection of segmental arteries due to dense adventitial fibrosis around the right lower lobe pulmonary artery. This approach may be considered as an alternative to the so-called "en masse" lobectomy and a way to avoid conversion to thoracotomy.PMID:3379459...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Dario Amore Dino Casazza Alessandro Saglia Pasquale Imitazione Umberto Caterino Carlo Curcio Source Type: research

Recurrent tracheal tumor with a critical airway requiring 'Y' stent - unique presentation of tuberculosis
We report an extremely rare case of isolated paratracheal lymphadenitis due to tuberculosis, eroding the trachea and presented a lower tracheal tumor, which recurred again after complete debulking. Finally, the disease required a 'Y' stent placement, to stabilize the airway following the second recanalization. We discuss the incidence, differential diagnosis, and the bronchoscopic, interventional aspects of this entity.PMID:33794588 | DOI:10.4081/monaldi.2021.1578 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Venugopal Jaganathan Santhakumar Subramanian Deepak T Hari Source Type: research

Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1586. Online ahead of print.ABSTRACTInflammatory myofibroblastic tumors (IMT) are rare soft tissue tumors of intermediate malignant potential occurring usually in children and adolescents. Treatment options for advanced diseases are limited. A 35-year-old lady presented to us with fever, cough and decreased appetite. On evaluation, she was diagnosed with left lung IMT. She underwent surgery and developed recurrence with pleural nodules after two years. Immunohistochemistry showed positivity for ALK (diffuse). Since recent evidence suggested that crizotinib is e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Abhenil Mittal Aarushi Gupta Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Indirect comparison between ferric carboxymaltose and oral iron replacement in heart failure with reduced ejection fraction: a network meta-analysis
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1703. Online ahead of print.ABSTRACTTreatment of iron deficiency (ID) in patients with heart failure (HF) has improved symptoms, quality of life, exercise capacity and has reduced hospitalizations in randomized controlled trials (RCTs) and meta-analyses. Intravenous ferric carboxymaltose (FCM) provided convincing results in this field, while oral iron supplementation failed. However, FCM and oral iron were compared to placebo, and a comparison between the two strategies is still lacking. We aimed to fill this gap of knowledge with an indirect comparison between...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Edoardo Sciatti Ugo Nesti Andrea Di Lenarda Source Type: research

Continuous positive airway pressure therapy in the management of hypercapnic cardiogenic pulmonary edema
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1725. Online ahead of print.ABSTRACTContinuous positive airway pressure (CPAP) therapy or non-invasive ventilation (NIV) represent the first line therapy for acute cardiogenic pulmonary edema (CPE) together with medical therapy. CPAP benefits in acute CPE with normo-hypocapnia are known, but it is not clear whether the use of CPAP is safe in the hypercapnic patients. The aim of this study is to evaluate CPAP efficacy in the treatment of hypercapnic CPE. We enrolled 9 patients admitted to the emergency room with diagnosis of acute CPE based on history, clinical e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Alfonso Sforza Mario Guarino Claudia Sara Cimmino Arturo Izzo Giovanna Cristiano Costantino Mancusi Gerolamo Sibilio Maria Viviana Carlino Source Type: research

Bleeding events in COVID-19: the other side of the coin?
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the ant...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Antonietta Coppola Anna Annunziata Maria Rosaria Gioia Giuseppe Fiorentino Source Type: research

Post COVID-19 tuberculosis: An emerging threat of pandemic
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1749. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) pandemic has hit the world hard. Millions of people have died due to the infection and several have suffered with what are now known as post COVID-19 squeal. Among these squeals one is immunosuppression which leaves patients prone to severe opportunistic infection. We here report a case of young female who was infected by COVID-19 and later developed cavitary pneumonia which upon investigation turned out to be due to mycobacterium tuberculosis. Th...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Aqusa Zahid Nousheen Iqbal Sarosh Moeen Muhammad Irfan Source Type: research

Non-invasive ventilation in the elderly - never too late!
Monaldi Arch Chest Dis. 2021 Apr 1. doi: 10.4081/monaldi.2021.1796. Online ahead of print.ABSTRACTDear Editor, Practising evidence-based medicine in an ageing population is challenging. Nevertheless, using age as a diagnostic or therapeutic procedure contraindication is less and less common. Domiciliary non-invasive ventilation (NIV) in chronic respiratory failure patients has been largely used; however, data from older people is scarce...PMID:33794594 | DOI:10.4081/monaldi.2021.1796 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Leonor Mendon ça Almeida Maria Jacob Mafalda Van Zeller Tiago Pinto Miguel Gon çalves Marta Drummond Source Type: research

The initial experience of COVID-19 vaccination from a tertiary care centre of India
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1816. Online ahead of print.ABSTRACTTo the Editor Drugs Controller General of India (DCGI) has approved the Bharat biotech vaccine against COVID-19, which is a locally manufactured inactivated vaccine named ''COVAXIN'' in collaboration with the Indian council of medical research (ICMR) on 3rd January 2021 for emergency use along with the "Covishield" Oxford-AstraZeneca vaccine manufactured locally by the Serum Institute of India... *The Safdarjung COVID-19 Vaccination group: KR Meena (Professor, Paediatrics), U Venkatesh (Assistant Professor, Communit...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: R K Srivastava Pranav Ish Safdarjung Covid-Vaccination Group Source Type: research

Imaging the COVID-19: a practical guide
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1630. Online ahead of print.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) represents the first medical catastrophe of the new millennium. Although imaging is not a screening test for COVID-19, it plays a crucial role in evaluation and follow-up of COVID-19 patients. In this paper, we will review typical and atypical imaging findings of COVID-19.PMID:33794596 | DOI:10.4081/monaldi.2021.1630 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Francesco Agnello Lidia Rabiolo Emanuele Grassedonio Patrizia Toia Federico Midiri Luigi Spatafora Francesco Matteini Lorenzo Tes è Ludovico La Grutta Massimo Galia Source Type: research

How to avoid "en masse" lobectomy using VATS technique in presence of hilar fibrosis
Monaldi Arch Chest Dis. 2021 Mar 19. doi: 10.4081/monaldi.2021.1633. Online ahead of print.ABSTRACTPerivascular fibrosis is technically one of the most challenging issue to manage during thoracoscopic lobectomy and it is associated with increased risk of hemorrhagic injury. Here we report a case of thoracoscopic right lower lobectomy performed with individual dissection of segmental arteries due to dense adventitial fibrosis around the right lower lobe pulmonary artery. This approach may be considered as an alternative to the so-called "en masse" lobectomy and a way to avoid conversion to thoracotomy.PMID:3379459...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Dario Amore Dino Casazza Alessandro Saglia Pasquale Imitazione Umberto Caterino Carlo Curcio Source Type: research

Recurrent tracheal tumor with a critical airway requiring 'Y' stent - unique presentation of tuberculosis
We report an extremely rare case of isolated paratracheal lymphadenitis due to tuberculosis, eroding the trachea and presented a lower tracheal tumor, which recurred again after complete debulking. Finally, the disease required a 'Y' stent placement, to stabilize the airway following the second recanalization. We discuss the incidence, differential diagnosis, and the bronchoscopic, interventional aspects of this entity.PMID:33794588 | DOI:10.4081/monaldi.2021.1578 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Venugopal Jaganathan Santhakumar Subramanian Deepak T Hari Source Type: research

Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1586. Online ahead of print.ABSTRACTInflammatory myofibroblastic tumors (IMT) are rare soft tissue tumors of intermediate malignant potential occurring usually in children and adolescents. Treatment options for advanced diseases are limited. A 35-year-old lady presented to us with fever, cough and decreased appetite. On evaluation, she was diagnosed with left lung IMT. She underwent surgery and developed recurrence with pleural nodules after two years. Immunohistochemistry showed positivity for ALK (diffuse). Since recent evidence suggested that crizotinib is e...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Abhenil Mittal Aarushi Gupta Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Indirect comparison between ferric carboxymaltose and oral iron replacement in heart failure with reduced ejection fraction: a network meta-analysis
Monaldi Arch Chest Dis. 2021 Mar 31. doi: 10.4081/monaldi.2021.1703. Online ahead of print.ABSTRACTTreatment of iron deficiency (ID) in patients with heart failure (HF) has improved symptoms, quality of life, exercise capacity and has reduced hospitalizations in randomized controlled trials (RCTs) and meta-analyses. Intravenous ferric carboxymaltose (FCM) provided convincing results in this field, while oral iron supplementation failed. However, FCM and oral iron were compared to placebo, and a comparison between the two strategies is still lacking. We aimed to fill this gap of knowledge with an indirect comparison between...
Source: Monaldi Archives for Chest Disease - April 2, 2021 Category: Respiratory Medicine Authors: Edoardo Sciatti Ugo Nesti Andrea Di Lenarda Source Type: research