Contrast transesophageal three dimensional echocardiographic imaging for patent foramen ovale: a needful role?
We report a case of a 55-year-old male admitted for cardiogenic embolic ischemic stroke work up. A transesophageal (TE) echocardiography (E) with contrast study to rule out patent foramen ovale (PFO) was performed; two-dimensional (2D) analysis did not detect any bubbles passage during Valsalva manoeuvre in the standard 2D cross sectional planes; further real time three-dimensional (3D) TEE imaging revealed passage of bubbles in the left atrium (LA) by both real-time 3DTEE imaging and by the 2D unconventional cross-sectional planes allowed by 3DTEE imaging. Even though 2DTEE is considered to be the gold standard modality f...
Source: Monaldi Archives for Chest Disease - October 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Revisiting bronchoscopic intratumoral chemotherapy in malignant central airway obstruction via EUS-B approach and its review of literature.
Authors: Niwas R, Chawla G, Pareek P, Chauhan NK, Dutt N Abstract Critical central airway obstruction has always been a dreaded complication to which interventional pulmonologist commonly encounters. There have been various modalities which are used for the management and palliation, which includes mechanical coring, laser, cryoextraction, electrocautery and airway stenting. Rigid bronchoscopy with or without jet ventilation has been corner stone of therapeutics and palliation of central airway obstruction. There are only a few conditions where it is not possible to use rigid bronchoscopy. Here we report a case of ...
Source: Monaldi Archives for Chest Disease - October 20, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Management and outcomes of patients hospitalized with severe COVID-19 at a tertiary care center in midwestern United States.
We report our experience ofmanagement and outcomes of hospitalized patients with COVID-19 at a large tertiary-care center in Midwestern United States. Of 658 patients presenting to our tertiary care center, 217 needed hospitalization, majority (77%) of whom were severely sick requiring admission to the intensive care unit (ICU). All received corticosteroids, and 78% of the patients received tocilizumab. More than two-thirds of the patients received anticoagulation and 80% of patients in the ICU had prone-positioning. The median duration of hospitalization was 12 days (interquartile range, 8 to16), median&nbs...
Source: Monaldi Archives for Chest Disease - October 20, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Human disease caused by < em > Streptococcus alactolyticus < /em > : a case report of native valve infective endocarditis and review of the literature.
Human disease caused by Streptococcus alactolyticus: a case report of native valve infective endocarditis and review of the literature. Monaldi Arch Chest Dis. 2020 Oct 16;90(4): Authors: Mylonas CC, Gomatou G, Poulakou G, Moraitou E, Syrigos K Abstract Streptococcus alactolyticus, a member of the Streptococcus bovis/Streptoccus equinus complex, is primarily hosted in the gastrointestinal tract of animals and rarely of humans, with only scarce reports relating to human disease. We herein present a case of subacute infective endocarditis (IE) caused by S. alactolyticus in a 64-year old male with pre-exi...
Source: Monaldi Archives for Chest Disease - October 20, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Occult carcinoma penis presenting as malignant pleural effusion.
Authors: Dixit R, Goya M, Pawar KS, Kasliwal N, Agarwal S Abstract A case of left sided malignant pleural effusion is described in a 41-year-old male, his initial workup for primary site of malignancy was unknown but later found to have hidden squamous cell carcinoma of penis which is one of the rarest site of malignancy that metastasise to pleura. Penile carcinoma manifesting with pleural metastasis and pleural effusion as initial presentation has not been reported previously. PMID: 33003693 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - October 4, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Aortic stenosis calcium scoring in a racially mixed sample.
Authors: Brito D, Goykhman I, Lo KB, Alhamshari Y, Peñalver JL, Aguilar F, Quintero E, Kalla A, Friend E, Pressman GS Abstract Aortic stenosis (AS) is common and increasing in prevalence as the population ages. Using computed tomography (CT) to quantify aortic valve calcification (AVC) it has been reported that men have greater degrees of calcification than women among subjects with severe AS. These data, however, were derived in largely Caucasian populations and have not been verified in non-Caucasian subjects. This retrospective study identified 137 patients with severe AS who underwent valve replacement a...
Source: Monaldi Archives for Chest Disease - October 4, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Psychological morbidity in interstitial lung disease: a study from India.
Authors: Rajpoot A, Garg K, Saini V, Gupta N Abstract Evaluation of mental health in chronic lung diseases like interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) has always been neglected and underrated. The aim of the study was to determine the psychological morbidity in patients of ILD and to determine its various socio-clinical and psychological correlates. A cross-sectional clinic based descriptive study with 50 ILD patients, 30 COPD patients and 30 healthy controls was undertaken. Psychological distress was assessed using different psychological scales, like Genera...
Source: Monaldi Archives for Chest Disease - October 4, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

First MDCT evidence of ruptured aberrant left subclavian artery aneurysm in right aortic arch, Kommerell's diverticulum and extrapleural hematoma treated by emergency thoracic endovascular aortic repair.
We report the case of a 74-year-old man suffering from this emergency ondition with mediastinal hematoma mostly extending to the left-side extrapleural cavity. The patient underwent successful emergency thoracic endovascular aortic repair and an Amplatzer vascular plug was placed into the first segment of the ALSA. Post-procedural imaging showed complete exclusion of the aneurysm. Emergency endovascular repair can be effective in such cases. PMID: 32990689 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - October 1, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Spontaneous pneumomediastinum in COVID-19 pneumonia.
In conclusion, spontaneous pneumomediastinum is a possible complication of severe COVID-19 pneumonia that can affect patient management and clinical outcomes. PMID: 32990690 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - October 1, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Of onions and men: Report of cavitary community acquired pneumonia due to < em > Burkholderia cepacia < /em > complex in an immunocompetent patient and review of the literature.
We describe a case of an otherwise healthy, community-dwelling man who presented with subacute cavitary lung disease, the causative organism of which turned out to be Burkholderia cepacia complex.  Our report is accompanied by a review of the literature, which identified an additional eleven cases in the same category.  We analyze all of the available cases for the emergence of any identifiable patterns or peculiarities. PMID: 32959626 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Telemedicine during COVID-19: a survey of Health Care Professionals' perceptions.
Authors: Elawady A, Khalil A, Assaf O, Toure S, Cassidy C Abstract The National Health Service (NHS) has rapidly adopted telemedicine solutions as an alternative to face-to-face consultations during the COVID-19 pandemic. The majority of HCPs (Healthcare Professionals) were unfamiliar with Telemedicine prior to the current pandemic. Remote consultation is expected to continue for the foreseeable future, thus we designed this survey. A survey designed to evaluate the use of telephone consultation by HCPs, assessing its implementation, challenges and drawbacks. A web link survey conducted through SurveyMonkey was sen...
Source: Monaldi Archives for Chest Disease - September 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Hospital treatment of severe acute exacerbation of chronic obstructive pulmonary disease in COVID-19 situation: back to basics.
Authors: Upadhya P, Vadala R, A A Abstract Patients of chronic obstructive pulmonary disease (COPD) during COVID-19 pandemic have higher morbidity. Treatment of these patients require aerosolization procedures like nebulization and noninvasive modalities for ventilation like non-invasive ventilation (NIV) and high flow nasal cannula (HFNC). Role of these procedures in corona virus transmission when treating a case of acute exacerbation of chronic obstructive pulmonary disease should be further studied. PMID: 32960000 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Pleural effusion. An unfamiliar presentation of ABPA.
We report the case of a 17-year-old male who presented with complaints of fever, cough and increasing shortness of breath for 3 weeks. Patient had breathlessness with seasonal variation. Patient had right lower lobe consolidation with pleural effusion which did not respond to antibiotics. Pleural fluid was exudate with neutrophilic predominance and low ADA. Skin prick test for Aspergillus fumigatus was positive, both total IgE and specific IgE against Aspergillus fumigatus were raised. PMID: 32945640 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

COVID-19 associated viral myocarditis: does it exist?
Authors: Verma V, Sondhi S, Sharma R, Mahajan K Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a lethal pandemic that has claimed millions of lives worldwide. While respiratory involvement is the most common and most virulent manifestation of COVID-19, there is enough data to suggest that myocardial injury reflected through elevated troponin levels is seen in around 7-28% of patients and is related with increased morbidity and mortality. PMID: 32945641 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Metastatic pulmonary calcification diagnosed by transbronchial cryobiopsy.
We describe a case where this pathology is observed associated with bone lithic lesions and kidney failure and it was diagnosed with transbronchial cryobiopsy. PMID: 32945642 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

SeXX and COVID-19: tussle between the two.
Authors: Patil A, Tripathy JP, Deshmukh V, Sontakke B, Tripathi SC Abstract Novel coronavirus disease (COVID-19) has affected nearly 7 million individuals and claimed more than 0.4 million lives to date. There are several reports of gender differences related to infection and death due to COVID-19. This raises important questions such as "Whether there are differences based on gender in risk and severity of infection or mortality rate?" and "What are the biological explanation and mechanisms underlying these differences?" Emerging evidences have proposed sex-based immunological, genetic, and hor...
Source: Monaldi Archives for Chest Disease - September 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Different presentation of pulmonary parenchymal disruption in COVID-19 pneumonia. Case series of Sub-Intensive Care Unit in Naples, Italy.
Authors: Polistina GE, Simioli F, Imitazione P, Lanza M, Annunziata A, Fiorentino G Abstract The coronavirus disease 2019 (COVID-19) is a recent pandemic that affected more than 5 million people worldwide. Chest high resolution computed tomography (HRCT) is an essential tool in diagnosis and management of the disease. Pulmonary parenchymal opacity is a typical sign of the disease, but not the only one. Pneumothorax, pneumomediastinum, bronchiectasis and cysts are probably underrated complications of COVID-19 that can worsen prognosis, in terms of prolonged hospitalization and need of oxygen therapy. In our single c...
Source: Monaldi Archives for Chest Disease - September 21, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Chronic granulomatous 'Aspergillus lung mass'.
We report the case of a young immunocompetent male with no underlying lung disease, who presented with an incidentally detected 'infective mass' lesion in the lung associated with minimal respiratory symptoms. The diagnostic challenges posed by the unusual clinical, radiological and histological picture as well as the therapeutic dilemmas faced are discussed in this report. PMID: 32893609 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 8, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Cystic fibrohistiocytic tumour of the lung presenting with recurrent pneumothoraces: a case report.
Authors: Kakos C, Lampridis S, Geropoulos G, Khiroya R, Antonopoulos A, Mitsos S, Panagiotopoulos N Abstract Cystic fibrohistiocytic tumour of the lung is a very rare pathological entity that occurs either as a primary pulmonary neoplasm or as a metastasis from skin lesions called cellular fibrous histiocytomas. Herein, we present the case of a 19-year old man with a history of recurrent pneumothoraces who was managed surgically and was eventually diagnosed with cystic fibrohistiocytic tumour of the lung. Clinicians should include this disease in the differential diagnosis of pulmonary cystic lesions and be aware o...
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

COVID-19 and tuberculosis co-infection: a neglected paradigm.
We present this review as the co-infection of COVID-19 with TB has not been assessed yet, imposing a greater global threat. We suggest few measures to be implemented without delay for effectively screening the suspects of co-infection and also follow up of non-suspect patients in the post-pandemic phase. PMID: 32885625 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

An unusual cause of 'tree-in-bud' appearance in CT-chest during COVID-19 pandemic.
Authors: Sharma A, Narayanan B, Pal N, Taye S Abstract 'Tree-in-bud' (TIB) appearance in computed tomography (CT) chest is most commonly a manifestation of infection. We here describe an unusual cause of TIB during the COVID-19 pandemic. A young male patient who had a history of fever, cough, and respiratory distress presented in the emergency department. As these symptoms matched with coronavirus infection, the COVID-19 test was done, which was found negative. He was then moved to the intensive care unit where he developed severe acute respiratory distress syndrome and was put on mechanical ventilation. Furth...
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

SLE presenting as DAH and relapsing as refractory retinitis.
Authors: Ish S, Sharma D, Ish P Abstract Dear Editor, A 17-year-old boy, diagnosed with Systemic Lupus Erythematosus (SLE), presented to ophthalmology department with gradual painless diminution of vision in both eyes (right more than left). He had already received 6 pulses of cyclophosphamide and steroids at monthly intervals one year back for diffuse alveolar hemorrhage (DAH) and was on maintenance oral 40 mg prednisolone and 3 grams mycophenolate mofetil (MMF). There was no history of oliguria, skin rash, joint pain, oral ulcers, photosensitivity or any neurological deficit in this presentation. T...
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Ventricular tachycardia triggered by pregnancy in left-ventricular non-compaction cardiomyopathy: a controversial indication to automated defibrillator implantation.
In conclusion, the management of malignant arrhythmias during pregnancy is one of the concerns for patients with LVNC and requires a careful approach in third-level centers. PMID: 32885930 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A case of vasospastic angina. Vasospasm physiopathology: a new therapeutic role for ranolazine?
We report the case of a 40-year-old man, transferred from another hospital to our ICU because of acute coronary syndrome. Coronarography did not show coronary stenosis. Twenty-four hours monitoring EKG allowed diagnosis of Prinzmetal angina and appropriate therapy was administered. Six months after discharge due recurrence of symptoms, ranolazine was added to therapy. After one year the patient is symptoms free. PMID: 32885931 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Hypersensitivity pneumonitis: clinical, radiological and pathological profile of 103 patients from North India.
In this study we are presenting clinical, radiological and bronchoscopic finding of 103 HP patients. We retrospective analysis of 5½ years HP patient's data from a chest institute of India. The diagnosis of HP was considered with following criteria: i) known exposure to an inciting antigen; ii) presence of respiratory symptoms; iii) radiologic evidence of diffuse lung disease; iv) no other identifiable cause; v) lung biopsy specimen that demonstrated features of HP; and vi) bronchoalveolar lavage lymphocytosis (≥30%). The mean ±SD age was 47±12.8 years; 67% were female. The common symptoms were coug...
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Chest percussion, a common yet underutilized art.
Authors: Gupta NK, Kumar R, Puri HV, Gupta N, Yadav SR, Ish P Abstract Dear Editor Long years of respiratory medicine practice lets one develop a clinical instinct which certainly aids in diagnostic acumen... PMID: 32885933 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A multicenter approach to evaluate omalizumab effectiveness in Samter's triad.
Authors: Cameli P, D'Alessandro M, Bergantini L, Silvestri E, Romaldi A, Emmi G, Parronchi P, Bargagli E Abstract Omalizumab proved to be very effective in improving control of severe atopic asthma. Many small-sized studies suggested a potential role for omalizumab in the management of aspirin-exacerbated respiratory disease. The aim of this study is to describe the effectiveness of omalizumab in a multicentre group of patients with Samter's triad. We retrospectively enrolled eight patients (5 females) with Samter's triad who underwent at least one year of omalizumab therapy. Clinical data, functional parameters an...
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman.
We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature. PMID: 32885935 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 5, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Unusual cause of laryngeal dyspnea and swallowing troubles in a 2-year old child.
We report the case of multifocal plexiform neurofibromas in a 2-year-old child with cervical mass obstructing the trachea causing respiratory distress. A cervical ultrasound examination was performed followed by enhanced CT and MRI. Imaging revealed an expansive cervical mass extended from the base of the skull to the mediastinum associated with similar pelvic and sacral foraminal masses. The target like MRI aspect on T2-weighted images was suggestive of the neural origin. Biopsy under ultrasound control confirmed the diagnosis of plexiform neurofibroma. PMID: 32875775 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - September 4, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Bedside wireless lung ultrasound for the evaluation of COVID-19 lung injury in senior nursing home residents.
Authors: Dini FL, Bergamini C, Allegrini A, Scopelliti M, Secco G, Miccoli M, Boni S, Brigada R, Perlini S Abstract Lung Ultrasound (LUS) is regarded to be potentially useful to diagnose lung injury in older adults living in nursing homes with suspected COVID-19 pneumonia. We aimed at evaluating presence lung injury among senior nursing home residents by LUS performed with portable wireless scanner echography. The study population consisted of 150 residents with a mean age of 88 years (85% female) residing in 12 nursing homes in Northern Italy. Subjects had to have a history of recent onset of symptoms compatible w...
Source: Monaldi Archives for Chest Disease - September 4, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Utilization of endobronchial electrocautery for removal of an impacted airway foreign body.
Authors: Nongpiur VN, Mittal S, Madan K, Mohan A, Hadda V Abstract Dear Editor, Aspiration of a foreign body into the tracheobronchial tree can occur at any age, though it occurs more commonly in children. In small children, the foreign body commonly gets lodged in the central airways (trachea and mainstem bronchi); hence, the presentation is usually sudden onset of cough and dyspnea or even lifethreatening respiratory failure in an otherwise healthy child. A witnessed aspiration or a history of aspiration can usually be elicited. PMID: 32735107 [PubMed - as supplied by publisher] (Source: Monald...
Source: Monaldi Archives for Chest Disease - August 2, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Endobronchial pulmonary blastoma - an unusual presentation of a rare lung malignancy and review of literature.
Authors: Shadrach BJ, Vedant D, Vishwajeet V, Jain P, Dutt N, Surekha B, Pareek P, Abhay Elhence P Abstract Biphasic pulmonary blastoma (BPB) is an extremely rare highly aggressive malignant tumor that arises from fetal lung tissue and has the classical biphasic histology of epithelial and mesenchymal components. It is usually seen in adults with a slight male predominance and smokers. Previously grouped along with well-differentiated fetal adenocarcinoma (WDFA), and pleuropulmonary blastoma (PPB), now it is considered a separate variant and grouped under sarcomatoid neoplasms. Symptoms include chest pain, cough, h...
Source: Monaldi Archives for Chest Disease - August 1, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Pulmonary Rehabilitation.
Authors: Polastri M, Nava S Abstract Commenting on this book is a great privilege and an opportunity to share some emerging aspects regarding the development of pulmonary rehabilitation. Indeed, appreciating the therapeutic value of this modality is possible because of continuous research and tireless commitment of all professionals involved in the care of patients with respiratory diseases and pulmonary-related impairments.... PMID: 32720775 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Immune status in sarcoidosis: one size does not fit all.
Authors: Papanikolaou I, Shigemitsu H, Afthinos A Abstract B-cell immunity and immunoglobulins are less commonly affected in sarcoidosis. We aimed to evaluate immune status in sarcoidosis patients. Retrospective chart review of sarcoidosis patients attending a out-patient clinic over 3 months period. Immunoglobulins levels were recorded (A, M, G, E) along with clinical and serological data. They were divided in group A (normal IgG), group B (increased IgG), group C (decreased IgG) and group D (decreased IgG and IgM and/or IgA). Of 50 subjects, 68% were females and 62% of Caucasian origin. 22 (44%) had normal IgG le...
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Simultaneous use of FDG-18 and < sup > 68 < /sup > Ga-citrate PET/CT for the differential diagnosis of sarcoidosis and malignant disease.
Simultaneous use of FDG-18 and 68Ga-citrate PET/CT for the differential diagnosis of sarcoidosis and malignant disease. Monaldi Arch Chest Dis. 2020 Jul 29;90(3): Authors: Tetikkurt C, Sayman H, Dedeoglu SE, Kubat B, Tetikkurt S Abstract A 67-year-old male presented with cutaneous rash, lassitude and fatigue of three weeks. Personal history included psoriasis and sarcoidosis. Physical examination revealed macular rash on the anterior chest wall. Laboratory results were within normal limits. Chest X-ray showed normal findings. Pulmonary function tests demonstrated a mild obstructive pattern and a mild d...
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

The validity of a daytime ambulatory blood pressure to diagnose masked hypertension.
Authors: Kinsara AJ, Elshiekh AH, Abuosa AM, Galzerano D, Abrar MB Abstract Masked hypertension (MH) is traditionally diagnosed with 24-hour ambulatory blood pressure monitoring (24-ABPM). This is relatively costly and could cause discomfort during the night. We studied the validity of daytime ABP (DT-ABPM) in young National Guard soldiers and determined the prevalence in comparison to the standard 24-ABPM. A prospective study of 196 soldiers aged 21-50 years, without a history of hypertension or antihypertensive medication use. Each participant was fitted with a 12h-ABPM. Patients were diagnosed with MH if the off...
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Light sedation or no-sedation in ICU: patient experience matters.
Authors: Mittal S, Mohan A, Madan K, Hadda V Abstract Dear Editor, We have been using sedation for a long time in intensive care units for patients on mechanical ventilation. Sedation aims at facilitating the patient's ability to remain comfortably connected to the ventilator and minimize oxygen consumption. The strategies for sedation vary from deep sedation and light sedation to nosedation. For the last two decades, light sedation with daily interruption is being practiced by most ICUs... PMID: 32724230 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Takotsubo cardiomyopathy in the setting of multiple sclerosis: a multifaceted phenomenon with important implications.
Authors: Yalta K, Taylan G, Yalta T, Yetkin E Abstract Dear Editor, Takotsubo cardiomyopathy (TTC) has been universally regarded as a unique form of reversible myocardial dysfunction associated with a variety of emotional and physical stressors. In their recently published elegant article, Dell'Aquila et al. have reported an interesting case of TTC triggered by an exacerbation of relapsing-remitting multiple sclerosis (MS). However, we would like to comment on this interesting case and its particular implications... PMID: 32724231 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 30, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A case of lung injury resembling diffuse pulmonary hemorrhage after the first administration of alemtuzumab in a patient with multiple sclerosis. Role of the HRCT.
We report here the case of a 25-year-old woman who has been admitted to our pulmonary clinic for the onset of chest pain, cough and haemoptysis, started one week after her first treatment with alemtuzumab for multiple sclerosis. Computed tomography (CT) scan of the chest at the admission showed diffuse and bilateral ground glass pulmonary opacities. Her symptoms resolved completely without any treatment, after the interruption of alemtuzumab, and CT scan of the chest performed one month later showed total disappearance of the pulmonary opacities. PMID: 32702962 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 27, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

A case report on expanding horizon of endobronchial ultrasound through esophagus.
We report a case of 70 years old man who has been referred from physician for the EBUS in view of hilar mass with mediastinal lymphadenopathy with pleural effusion. The endobronchial ultrasound through oesophagus (EUS-B) was done for thoracocentesis and lymph node cytology evaluation and ultimately endobronchial biopsy of hilar mass was done as rapid on-site (ROSE) analysis of lymph node was suggestive of necrotic tissue. The cytology report of lymph node and pleural effusion was positive for malignant cells. The final diagnosis was metastatic poorly differentiating adeno-squamous carcinoma. PMID: 32696627 [PubMed - in...
Source: Monaldi Archives for Chest Disease - July 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Diffuse alveolar hemorrhage secondary to plastic fume exposure: A case report.
Authors: Choudhari OK, Ojha UC, Gothi D, Spalgais S, Singh P, Rani A Abstract A 31-year non-smoker man, working in plastic making industry for 12 years presented with cough and streaking hemoptysis for 2 days. Computed tomography (CT) of chest showed patchy ground glass opacities with interlobular septal thickening in bilateral lung parenchyma. Fiber optic bronchoscopy (FOB) was done. Sequential lavage was taken which showed progressively increasing hemorrhagic fluid. His diffusion capacity for carbon monoxide (DLCO) was 38.08 mL/mmHg/Mi (126%) predicted on day 2 of admission, 32.36 ml/mmHg/Mi (106%) predicted on d...
Source: Monaldi Archives for Chest Disease - July 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Early trends of socio-economic and health indicators influencing case fatality rate of COVID-19 pandemic.
Authors: Asfahan S, Shahul A, Chawla G, Dutt N, Niwas R, Gupta N Abstract Coronavirus disease 2019, i.e. COVID-19, started as an outbreak in a district of China and has engulfed the world in a matter of 3 months. It is posing a serious health and economic challenge worldwide. However, case fatality rates (CFRs) have varied amongst various countries ranging from 0 to 8.91%. We have evaluated the effect of selected socio-economic and health indicators to explain this variation in CFR. Countries reporting a minimum of 50 cases as on 14th March 2020, were selected for this analysis. Data about the socio-economic indica...
Source: Monaldi Archives for Chest Disease - July 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Severe acute respiratory syndrome coronavirus-2 and pulmonary tuberculosis: convergence can be fatal.
Authors: Singh A, Prasad R, Gupta A, Das K, Gupta N Abstract Disease associated with SARS-CoV-2 also termed as Coronavirus disease 2019 or COVID-19, has become a potential threat to public health by spreading across more than 200 countries worldwide within a short span of time. Tuberculosis (TB) is already existing as unprecedented pandemic worldwide over several years. Both diseases have many overlapping features but there are striking differences too. There is usually chronicity of symptoms in TB as compared to acute or rapid progression in COVID-19. Little evidence exists regarding TB and COVID-19 coinfection. I...
Source: Monaldi Archives for Chest Disease - July 24, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Ventricular tachycardia: beginning and ending fate of a benign invasive cardiac lipoma.
We describe a case of a 14-year-old boy complaining of palpitations. ECG showed non-sustained ventricular tachycardia (NSVT). Echocardiography and cardiac MRI showed a large apical mass suggestive of a cardiac lipoma. The patient underwent open-heart surgery which detected a pericardial mass, partially attached to the myocardium, and crossed by the distal segment of LAD. This critical anatomical relationship prevents its complete resection. The biopsy confirmed mature fat tissue. Postoperatively, Propranolol was started for NSVT episodes. After 8 months, he presented with VT recurrence. A subcutaneous ICD (S-ICD) was impla...
Source: Monaldi Archives for Chest Disease - July 17, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Hemoptysis due to a large endobronchial mass successful regression after the use of high flow nasal cannula.
We report a patient who presented with hemoptysis and hypoxaemic respiratory failure second to a large mass obstructing the right main bronchus. High flow oxygen via nasal cannula was initiated with a quick improvement of the hemoptysis and the oxygen saturation. Thus, allowing the patient to be rapidly stabilized. PMID: 32672429 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 17, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Predictors of Intensive Care Unit admission in patients with coronavirus disease 2019 (COVID-19).
We examined 28 patients admitted to the Emergency Department (ED) and subsequently confirmed as cases of Covid-19. Patients received, at the admission to the ED, a diagnostic work-up including: patient history, clinical examination, an arterial blood gas analysis (whenever possible performed on room air), laboratory blood tests, including serum concentrations of interleukin-6 (IL-6), lung ultrasound examination and a computed tomography (CT) scan of the thorax. For each patient, as gas exchange index through the alveolocapillary membrane, we determined the alveolar-arterial oxygen gradient (AaDO⁠2) and the alveolar-arter...
Source: Monaldi Archives for Chest Disease - July 17, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Covid-19 and ex-smokers: an underestimated prognostic factor?
Authors: Carratù P, Boffi R, Dragonieri S, Munarini E, Veronese C, Portincasa P Abstract Dear Editor, The recent and explosive worldwide outbreak of Covid-19 leads many scientists and clinicians to identify the most responsible triggering risk factors in individuals without comorbidities, as well as potential prognostic factors. A notable field of research has been conducted on the role of smoking, which has been initially hypothesized as being a protective factor for Covid-19.... PMID: 32672431 [PubMed - as supplied by publisher] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 17, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Incidental diagnosis of lung adenocarcinoma following coronavirus OC 43 severe pneumonia.
We present the case of a women admitted to our department presenting with an acute manifestation of coronavirus OC43 pneumonia with underlying undiagnosed lung adenocarcinoma. PMID: 32664711 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 16, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

TAPSE/PASP use in heart failure: Implementing the evidence for simplicity.
Authors: Guazzi M Abstract Commentary to: "Assessment of right ventricular-arterial coupling by echocardiography in patients with heart failure with reduced to mid-range ejection fraction: impact on survival" by Rosa et al. PMID: 32657105 [PubMed - in process] (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 14, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Causes of hospitalization and characteristics of Algerian chronic obstructive pulmonary disease patients in Tizi-Ouzou: a retrospective study.
Authors: Ramdani I, Pescatore KA, Bouazza B Abstract Chronic obstructive pulmonary disease (COPD) is a progressive chronic inflammatory disease and the third cause of death worldwide in 2016. COPD epidemiology is well documented in high-income countries where the disease is well managed. However, the disease is neglected in low-income countries and there is lack of data. Our study aims to identify COPD patients' characteristics and hospital admission causes, and to determine disease etiologies and associated factors. A retrospective study was conducted in COPD Algerian patients using medical record data collected f...
Source: Monaldi Archives for Chest Disease - July 14, 2020 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research