Sulfated glyco-based hydrogels as self-healing, adhesive, and anti-inflammatory dressings for wound healing
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113915. doi: 10.1016/j.colsurfb.2024.113915. Online ahead of print.ABSTRACTHydrogels have emerged as a new type of wound dressing materials that involved in different stages of the healing processes. However, most of the existing wound dressings mainly offer a protective and moisturizing layer to prevent cross-infection, while the anti-inflammatory and anti-oxidative properties are frequently induced by extra addition of other bioactive molecules. Here, a novel type of sulfated glyco-functionalized hydrogels for wound dressing was prepared through the hybrid supramolecular co-...
Source: Colloids and Surfaces - April 17, 2024 Category: Biotechnology Authors: Baotong Ye Guodong Lu Jingjing Zhou Yi Li Yongxin Ma Yan Zhang Jinghua Chen Source Type: research

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet
CONCLUSIONS: The intake of lipids and simple carbohydrates were found to be associated with alteration in the glomerular ultrastructure. However, more studies are needed to evaluate not only the effects of high-protein and high-fat diets on components of the glomerular filtration barrier, but also renal physiology.PMID:38629653 | PMC:PMC11020636 | DOI:10.1590/acb392224 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 17, 2024 Category: Surgery Authors: Priscila Fernandes Dos Santos Diogo Benchimol de Souza Eduardo Jos é Lopes Torres Waldemar Silva Costa Francisco Jos é Barcellos Sampaio Bianca Martins Gregorio Source Type: research

Metabolomic reveals the responses of sludge properties and microbial communities to high nitrite stress in denitrifying phosphorus removal systems
Environ Res. 2024 Apr 15;252(Pt 2):118924. doi: 10.1016/j.envres.2024.118924. Online ahead of print.ABSTRACTNitrite, as an electron acceptor, plays a good role in denitrifying phosphorus removal (DPR); however, high nitrite concentration has adverse affects on sludge performance. We investigated the precise mechanisms of responses of sludge to high nitrite stress, including surface characteristics, intracellular and extracellular components, microbial and metabolic responses. When the nitrite stress reached 90 mg/L, the sludge settling performance was improved, but the activated sludge was aging. FTIR and XPS analysis reve...
Source: Environmental Research - April 17, 2024 Category: Environmental Health Authors: Rongrong Hou Jiandong Liu Peng Yang Haijun Liu Rongfang Yuan Ying Ji Hongfei Zhao Zhongbing Chen Beihai Zhou Huilun Chen Source Type: research

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet
CONCLUSIONS: The intake of lipids and simple carbohydrates were found to be associated with alteration in the glomerular ultrastructure. However, more studies are needed to evaluate not only the effects of high-protein and high-fat diets on components of the glomerular filtration barrier, but also renal physiology.PMID:38629653 | PMC:PMC11020636 | DOI:10.1590/acb392224 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 17, 2024 Category: Surgery Authors: Priscila Fernandes Dos Santos Diogo Benchimol de Souza Eduardo Jos é Lopes Torres Waldemar Silva Costa Francisco Jos é Barcellos Sampaio Bianca Martins Gregorio Source Type: research

Integrating bioprocess and metagenomics studies to enhance humic acid production from rice straw
This study aimed to examine the influence of a microbial consortium and other additives (chicken manure, urea, olive mill waste, zeolite, and biochar) on the composting process of rice straw and the subsequent production of humic acid. Results showed that among the fungal species,Thermoascus aurantiacus exhibited the most prominent impact in expediting maturation and improving compost quality, andBacillus subtilis was the most abundant bacterial species based on metagenomics analysis. The highest temperature, C/N ratio reduction, and amount of humic acid production (Respectively in lab 61  °C, 54.67%, 298 g kg−1 and i...
Source: World Journal of Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Source Type: research

Association of acylcarnitines with maternal cardiometabolic risk factors is defined by chain length: the S-PRESTO study
CONCLUSIONS: This study provides the metabolic and physiological basis of maternal carnitine homeostasis, which can be used in assessment of maternal cardiometabolic health at preconception to improve pregnancy outcomes.PMID:38625914 | DOI:10.1210/clinem/dgae255 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 16, 2024 Category: Endocrinology Authors: Li Chen Xue Ping Goh Anne K Bendt Karen Mei-Ling Tan Melvin Khee-Shing Leow Kok Hian Tan Jerry K Y Chan Shiao-Yng Chan Yap Seng Chong Peter D Gluckman Johan G Eriksson Markus R Wenk Sartaj Ahmad Mir Source Type: research

Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review
Carbohydr Res. 2024 Apr 10;539:109117. doi: 10.1016/j.carres.2024.109117. Online ahead of print.ABSTRACTPolygala tenuifolia is a traditional Chinese medicine with a long history of application, with the efficacy of suppressing cough, calming asthma, tranquilizing the mind, and benefiting the intellect. It is classified as a top-quality medicine in Shennong's Classic of Materia Medica. Polysaccharide is an important active ingredient in Polygala tenuifolia, which consists of several monosaccharides, including Ara, Gal, Glc, and so on. In this review, the preparation methods, structural characteristics, and biological activi...
Source: Carbohydrate Research - April 16, 2024 Category: Genetics & Stem Cells Authors: Yuanyuan Li Huimin Zheng Qiuhui Yao Yongbo Ma Lei Wang Qian Liu Yuhong Liu Source Type: research

Combined effects of azoxystrobin and oxytetracycline on rhizosphere microbiota of Arabidopsis thaliana
Environ Int. 2024 Apr 14;186:108655. doi: 10.1016/j.envint.2024.108655. Online ahead of print.ABSTRACTThe rhizosphere is one of the key determinants of plant health and productivity. Mixtures of pesticides are commonly used in intensified agriculture. However, the combined mechanisms underlying their impacts on soil microbiota remain unknown. The present study revealed that the rhizosphere microbiota was more sensitive to azoxystrobin and oxytetracycline, two commonly used pesticides, than was the microbiota present in bulk soil. Moreover, the rhizosphere microbiota enhanced network complexity and stability and increased c...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Yuke Zhu Mingjing Ke Zhitao Yu Chaotang Lei Meng Liu Yaohui Yang Tao Lu Ning-Yi Zhou W J G M Peijnenburg Tao Tang Haifeng Qian Source Type: research

Characterization of < em > Amycolatopsis < /em > 75iv2 dye-decolorizing peroxidase on < em > O < /em > -glycosides
Appl Environ Microbiol. 2024 Apr 16:e0020524. doi: 10.1128/aem.00205-24. Online ahead of print.ABSTRACTDye-decolorizing peroxidases are heme peroxidases with a broad range of substrate specificity. Their physiological function is still largely unknown, but a role in the depolymerization of plant cell wall polymers has been widely proposed. Here, a new expression system for bacterial dye-decolorizing peroxidases as well as the activity with previously unexplored plant molecules are reported. The dye-decolorizing peroxidase from Amycolatopsis 75iv2 (DyP2) was heterologously produced in the Gram-positive bacterium Streptomyce...
Source: Applied and Environmental Microbiology - April 16, 2024 Category: Microbiology Authors: Silja V älimets Peicheng Sun Ludovika Jessica Virginia Gijs van Erven Mark G Sanders Mirjam A Kabel Clemens Peterbauer Source Type: research

A sulfated exopolysaccharide derived from Chlorella sp. exhibiting in vitro anti- α-D-Glucosidase activity
This study aimed to isolate a polysaccharide-producing microalga from an extreme ecosystem and to evaluate its capacity to inhibit the α-D-glucosidase enzyme. Chlorella strain is isolated from hypersaline Lake in the Algerian desert. The exopolysaccharide extraction was performed by the concentration of free-cell supernatant in a rotary evaporator. The infrared analysis showed a characteristic footprint of carbohydrates with particular functional groups, such as sulfate. Gas chromatography-mass spectrometry has revealed a hetero-exopolysaccharide composed of galactose 35.75%, glucose 21.13%, xylose 16.81%, fructose 6.96%,...
Source: Archives of Microbiology - April 16, 2024 Category: Microbiology Authors: Karima Guehaz Zakaria Boual Alia Telli Hicham Meskher Hakim Belkhalfa Guillaume Pierre Philippe Michaud Alessandra Adessi Source Type: research

Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial
CONCLUSIONS: Diet-induced weight loss in women with lipedema can improve QoL. An energy-restricted LCD seems to be superior to a standard control diet in reducing pain.PMID:38627016 | DOI:10.1002/oby.24026 (Source: Obesity)
Source: Obesity - April 16, 2024 Category: Eating Disorders & Weight Management Authors: Julianne Lundanes Frida Sandnes Kari Hanne Gjeilo Patrik Hansson Sissel Salater Catia Martins Siren Nymo Source Type: research

Association of acylcarnitines with maternal cardiometabolic risk factors is defined by chain length: the S-PRESTO study
CONCLUSIONS: This study provides the metabolic and physiological basis of maternal carnitine homeostasis, which can be used in assessment of maternal cardiometabolic health at preconception to improve pregnancy outcomes.PMID:38625914 | DOI:10.1210/clinem/dgae255 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 16, 2024 Category: Endocrinology Authors: Li Chen Xue Ping Goh Anne K Bendt Karen Mei-Ling Tan Melvin Khee-Shing Leow Kok Hian Tan Jerry K Y Chan Shiao-Yng Chan Yap Seng Chong Peter D Gluckman Johan G Eriksson Markus R Wenk Sartaj Ahmad Mir Source Type: research

Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review
Carbohydr Res. 2024 Apr 10;539:109117. doi: 10.1016/j.carres.2024.109117. Online ahead of print.ABSTRACTPolygala tenuifolia is a traditional Chinese medicine with a long history of application, with the efficacy of suppressing cough, calming asthma, tranquilizing the mind, and benefiting the intellect. It is classified as a top-quality medicine in Shennong's Classic of Materia Medica. Polysaccharide is an important active ingredient in Polygala tenuifolia, which consists of several monosaccharides, including Ara, Gal, Glc, and so on. In this review, the preparation methods, structural characteristics, and biological activi...
Source: Carbohydrate Research - April 16, 2024 Category: Genetics & Stem Cells Authors: Yuanyuan Li Huimin Zheng Qiuhui Yao Yongbo Ma Lei Wang Qian Liu Yuhong Liu Source Type: research

Combined effects of azoxystrobin and oxytetracycline on rhizosphere microbiota of Arabidopsis thaliana
Environ Int. 2024 Apr 14;186:108655. doi: 10.1016/j.envint.2024.108655. Online ahead of print.ABSTRACTThe rhizosphere is one of the key determinants of plant health and productivity. Mixtures of pesticides are commonly used in intensified agriculture. However, the combined mechanisms underlying their impacts on soil microbiota remain unknown. The present study revealed that the rhizosphere microbiota was more sensitive to azoxystrobin and oxytetracycline, two commonly used pesticides, than was the microbiota present in bulk soil. Moreover, the rhizosphere microbiota enhanced network complexity and stability and increased c...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Yuke Zhu Mingjing Ke Zhitao Yu Chaotang Lei Meng Liu Yaohui Yang Tao Lu Ning-Yi Zhou W J G M Peijnenburg Tao Tang Haifeng Qian Source Type: research

Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial
CONCLUSIONS: Diet-induced weight loss in women with lipedema can improve QoL. An energy-restricted LCD seems to be superior to a standard control diet in reducing pain.PMID:38627016 | DOI:10.1002/oby.24026 (Source: Obesity)
Source: Obesity - April 16, 2024 Category: Eating Disorders & Weight Management Authors: Julianne Lundanes Frida Sandnes Kari Hanne Gjeilo Patrik Hansson Sissel Salater Catia Martins Siren Nymo Source Type: research