At the Crossroads of the Microbiome, Metabolism & Glycoscience
For the past decade, the topics of the microbiome and metabolomics have become vital to human biology and disease. While the microbiota and metabolism can shape many biological processes, recent studies demonstrate that the ability of microbes to not only influence carbohydrate metabolism but also decorate themselves in diverse carbohydrate structures can significantly influence the consequences of host-microbial interactions. However, unlike assays designed to interrogate microbial communities or examine metabolic changes in a high throughput manner, the tools needed to similarly dissect how microbial glycans influence ho...
Source: Videocast - All Events - March 24, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
2021 Annual Common Fund Glycoscience Program All Hands Meeting [Day2]
The NIH Common Fund Glycoscience Program is focused on creating new methodologies, tools, and technologies (MTTs) to study glycans. The MTTs developed are expected to be easily adapted by the broader biomedical research community. Achieving this goal is expected to allow investigators to fully explore the roles of carbohydrates in relevant biological models, pathways, and/or diseases of interest, rather than abandon such discovery due to a lack of tools or expertise. Initiatives of this program have been designed to encourage new strategies and high-risk approaches for methods and tool development with subsequent rapid tra...
Source: Videocast - All Events - June 4, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
2021 Annual Common Fund Glycoscience Program All Hands Meeting [Day 1]
The NIH Common Fund Glycoscience Program is focused on creating new methodologies, tools, and technologies (MTTs) to study glycans. The MTTs developed are expected to be easily adapted by the broader biomedical research community. Achieving this goal is expected to allow investigators to fully explore the roles of carbohydrates in relevant biological models, pathways, and/or diseases of interest, rather than abandon such discovery due to a lack of tools or expertise. Initiatives of this program have been designed to encourage new strategies and high-risk approaches for methods and tool development with subsequent rapid tra...
Source: Videocast - All Events - June 4, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
2021 NIH & FDA Glycoscience Research Day
The NIH Glycobiology Interest Group (GBIG), with support from the NIH Office of Intramural Research, the Food and Drug Administration (FDA) as well as NCI, NIGMS, and NIDDK will hold its fourteenth annual NIH& FDA-wide Glycoscience Research Day on June 1, 2021 (virtually). This event will explore a broad range of aspects of the glycosciences; promote communication and interaction among intramural laboratories, as well as with researchers from local universities; and facilitate collaboration. The meeting will include morning and afternoon platform sessions, an abstract competition, and virtual discussion. The Glycobiology I...
Source: Videocast - All Events - April 19, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
The NIH Common Fund Glycoscience Program: Frontiers in Carbohydrate Synthesis Symposium (Day 2)
This report noted the urgent need for broad access to chemically well-defined glycans and pointed out that while “ tremendous advances ” had been made, glycan synthesis remained “ relegated to specialized laboratories capable of producing only small quantities of a given glycan. ” They concluded that “ For glycoscience to advance, significant further progress in glycan synthesis is needed to create widely applicable methodologies that generate both large and small quantities of any glycan on demand. ” This symposium, organized by the Common Fund Glycoscience Program, will explore progress made on the synthesis...
Source: Videocast - All Events - January 12, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
The NIH Common Fund Glycoscience Program: Frontiers in Carbohydrate Synthesis Symposium
This report noted the urgent need for broad access to chemically well-defined glycans and pointed out that while “ tremendous advances ” had been made, glycan synthesis remained “ relegated to specialized laboratories capable of producing only small quantities of a given glycan. ” They concluded that “ For glycoscience to advance, significant further progress in glycan synthesis is needed to create widely applicable methodologies that generate both large and small quantities of any glycan on demand. ” This symposium, organized by the Common Fund Glycoscience Program, will explore progress made on the synthesis...
Source: Videocast - All Events - January 12, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
New Tools for Finding Glycans in the PDB & Using the Information to Model 3D Structures of Glycans and GlycoProteins
Glycans play a critical role in nearly all aspects of biology, ranging from how our bodies recognize and fight viruses and bacteria to how proteins are moved throughout our cells to perform different tasks. The Common Fund ’ s Glycoscience program (CF-GSP) is creating new resources, tools, and methods to make the study of glycans (sugars) more accessible to the broader research community. The Protein Data Bank (PDB) contains more than 160,000 3D structures of biological macromolecules 20% of which contain carbohydrates as ligands or as chemical modifications. Unfortunately, much of the PDB's carbohydrate structural data ...
Source: Videocast - All Events - July 28, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
