The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats.
CONCLUSION: Reinforcement of the staple-line with fibrin glue has no effect on the burst pressure after sleeve gastrectomy. More studies are needed to evaluate the precautions against leak after sleeve gastrectomy. PMID: 31618401 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Ozdenkaya Y, Olmuscelik O, Basim P, Saka B, Arslan NC Tags: Acta Cir Bras Source Type: research

Effect of miR-134 against myocardial hypoxia/reoxygenation injury by directly targeting NOS3 and regulating PI3K/Akt pathway.
CONCLUSION: This present work puts insights into the crucial effects of the miR-134/NOS3 axis in myocardial H/R injury, delivering a potential therapeutic technology in future. PMID: 31618402 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Xiao JM, Wang JJ, Sun LL Tags: Acta Cir Bras Source Type: research

Stereological analysis of elastic fibers of the corpus cavernosum of rats during the aging process.
Abstract PURPOSE: To evaluate changes in the quantity of elastic fibers in the corpora cavernosa of rats during the natural aging process, and to assess the degree of this change by determining volumetric density (Vv) at different ages via stereological analysis. METHODS: Forty-eight rats, raised under similar conditions, were subjected to the natural aging process and divided into four groups (G1 to G4), according to age at the time of penectomy (6, 9, 12, and 24 months, respectively). Histological sections of the middle segment of the penis were stained with Weigert's resorcin-fuchsin, and the volumetric de...
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Hota T, Lorenzini F, Melchioretto EF, Zeni M, Veronez DADL, Fraga R Tags: Acta Cir Bras Source Type: research

The effect of different flushing methods in a short peripheral catheter.
CONCLUSIONS: The uniform flush produced less damage to the vascular endothelium and surrounding tissues and was superior to the pulsed flush. However, the uniform flush is prone to thrombosis. PMID: 31618404 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Tong C, Peng X, Hu H, Wang Z, Zhou H Tags: Acta Cir Bras Source Type: research

Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury.
Abstract PURPOSE: To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury. METHODS: Fifty-one Wistar rats were randomly grouped into sham, I/R, and sevoflurane groups. After reperfusion, the structural change of the lung was measured by Smith score, the wet and dry weights (W/D) were determined, malondialdehyde (MDA) myeloperoxidase (MPO) content was determined colorimetrically and by fluorescence, respectively, and matrix metalloprotein-9 (MMP-9) mRNA was quantified by RT-PCR. Biopsy and morphological analyses were performed on liver tissue, act...
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Xu G, Wang X, Xiong Y, Ma X, Qu L Tags: Acta Cir Bras Source Type: research

Effects of cyclosporine on ischemia-reperfusion injuries in rat kidneys. An experimental model.
el PA Abstract PURPOSE: To assess Cyclosporine A (CsA) therapy at an intraperitoneal dose of 15 mg.kg -1 in a rodent model of non-septic renal ischemia. METHODS: Twenty male Wistar rats were randomized to receive CsA therapy or none therapy before undergoing 30 minutes of renal ischemia followed by reperfusion. Additionally, 10 rats were randomized to undergo the same surgical procedure of the aforementioned animals with neither ischemia nor CsA therapy. Twelve hours after kidney ischemia, the left kidneys were evaluated for histological injury according to Park's criteria. Serum creatinine (Cr), urea nitroge...
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Oliveira ACC, Módolo NSP, Domingues MAC, Schwingel PA Tags: Acta Cir Bras Source Type: research

Mitigating effect of tanshinone IIA on ventricular remodeling in rats with pressure overload-induced heart failure.
Abstract PURPOSE: To investigate the effect of tanshinone IIA (TIIA) on ventricular remodeling in rats with pressure overload-induced heart failure. METHODS: Pressure overload-induced heart failure model (abdominal aortic coarctation) was established in 40 rats, which were divided into model and 5, 10 and 20 mg/kg TIIA groups. Ten rats receiving laparotomy excepting abdominal aortic coarctation were enrolled in sham-operated group. The 5, 10 and 20 mg/kg TIIA groups were treated with 5, 10 and 20 mg/kg TIIA, respectively, for 8 weeks. RESULTS: Compared with model group, in 20 mg/kg TIIA group the left ve...
Source: Acta Cirurgica Brasileira - October 18, 2019 Category: Surgery Authors: Li X, Xiang D, Shu Y, Zeng X, Li Y Tags: Acta Cir Bras Source Type: research

Botulinum toxin as a treatment for short bowel syndrome in rats.
CONCLUSION: This may provide a new promising approach to the surgical treatment of SBS. PMID: 31531527 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 16, 2019 Category: Surgery Authors: Marques ICS, Minto SB, Marques MQ, Ribeiro J, Moraes PC, Sbragia Neto L, Garcia SB Tags: Acta Cir Bras Source Type: research

Splenic ischemic preconditioning attenuates oxidative stress induced by hepatic ischemia-reperfusion in rats.
ma EY Abstract PURPOSE: To evaluate the effects of splenic ischemic preconditioning (sIPC) on oxidative stress induced by hepatic ischemia-reperfusion in rats. METHODS: Fifteen male Wistar rats were equally divided into 3 groups: SHAM, IRI and sIPC. Animals from IRI group were subjected to 45 minutes of partial liver ischemia (70%). In the sIPC group, splenic artery was clamped in 2 cycles of 5 min of ischemia and 5 min of reperfusion (20 min total) prior to hepatic ischemia. SHAM group underwent the same surgical procedures as in the remaining groups, but no liver ischemia or sIPC were induced. After 1h, hep...
Source: Acta Cirurgica Brasileira - September 16, 2019 Category: Surgery Authors: Costa CCC, Pereira NG, Machado ALM, Dórea MA, Cruz RMMD, Silva RC, Domingues RJS, Yasojima EY Tags: Acta Cir Bras Source Type: research

New training model using chickens intestine for pediatric intestinal anastomosis.
CONCLUSION: The new training model using chickens' intestine for infant intestinal anastomosis is low-cost, easy-to-make and easy available. PMID: 31531529 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 16, 2019 Category: Surgery Authors: Santos DRD, Calvo FC, Feijó DH, Araújo NP, Teixeira RKC, Yasojima EY Tags: Acta Cir Bras Source Type: research

Comparison of the prognostic value of platelet-based prognostic models in patients with malignant hepatic tumors after TACE therapy.
CONCLUSION: This study showed that the APGA, a platelet-based prognostic score, was an independent marker of prognosis in patients with malignant hepatic tumors after TACE and was superior to the other platelet-based prognostic scores in terms of prognostic ability. PMID: 31531530 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 16, 2019 Category: Surgery Authors: Du QC, Hu CL, Wang YY, Zhou Y Tags: Acta Cir Bras Source Type: research

Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats.
CONCLUSIONS: The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction. PMID: 31531536 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Ilgenfritz Neto J, Aydos RD, Silva IS, Takita LC, Abreu AC, Silva CAC, Faleiros KB, Santiago EML, Ramalho RT Tags: Acta Cir Bras Source Type: research

Intermittent vibrations accelerate fracture healing in sheep.
CONCLUSIONS: Clinical healing effects should be the top concern. Quantitative analyses of bone microstructure and of finite element mechanics on the process of fracture healing need to be further investigated. PMID: 31531537 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Mu D, Yu J, Lin J, Li C, Hao B, Gu F, Liu C, Tan L, Zhu D, Zhang X Tags: Acta Cir Bras Source Type: research

Comparative study of four different types of intraperitoneal mesh prostheses in rats.
Abstract PURPOSE: To compare four types of mesh regarding visceral adhesions, inflammatory response and incorporation. METHODS: Sixty Wistar rats were divided into four groups, with different meshes implanted intraperitoneally: polytetrafluoroethylene (ePTFE group); polypropylene with polydioxanone and oxidized cellulose (PCD); polypropylene (PM) and polypropylene with silicone (PMS). The variables analyzed were: area covered by adhesions, incorporation of the mesh and inflammatory reaction (evaluated histologically and by COX2 immunochemistry). RESULTS: The PMS group had the lowest adhesion area (63.1%)...
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Fuziy RA, Artigiani Neto R, Caetano Junior EM, Alves AKS, Lopes Filho GJ, Linhares MM Tags: Acta Cir Bras Source Type: research

Short-term use of resveratrol in alloplastic graft material applied with calvarial bone defects in rats.
CONCLUSION: Resveratrol treatment was thought to be an alternative and supportive drug for implant application by inducing new bone formation in the calvaral defect region as a result of short-term treatment. PMID: 31531539 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Laçin N, Deveci E Tags: Acta Cir Bras Source Type: research

Protective roles of Pyracantha fortuneana extract on acute renal toxicity induced by cadmium chloride in rats.
Abstract PURPOSE: To investigate the protective roles of pyracantha fortune fruit extract (PFE) on acute renal toxicity induced by cadmium chloride (CdCl2) in rats. METHODS: Rats were pretreated with PFE and consecutively injected with CdCl2 (6.5 mg/kg) for 5 days. RESULTS: The concentration of Cd, kidney weight, malondialdehyde (MDA), and nitric oxide (NO) production were remarkably increased in CdCl2 group as well as the levels of plasma uric acid, urea, and creatinine (P
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Ke Y, Yu K, Zeng W, Lian G Tags: Acta Cir Bras Source Type: research

Astragaloside IV alleviates myocardial ischemia-reperfusion injury in rats through regulating PI3K/AKT/GSK-3 β signaling pathways.
Astragaloside IV alleviates myocardial ischemia-reperfusion injury in rats through regulating PI3K/AKT/GSK-3β signaling pathways. Acta Cir Bras. 2019 Sep 12;34(7):e201900708 Authors: Wei D, Xu H, Gai X, Jiang Y Abstract PURPOSE: To investigate the effect of astragaloside IV (As-IV) on myocardial ischemia-reperfusion (I/R) injury in rats and reltaed mechanisms. METHODS: Sixty rats were randomly divided into sham-operated, control I/R and 2.5, 5 and 10 mg/kg As-IV groups, 12 rats in each group. The later three groups were intragastrically administered with As-IV for 7 days, with a dose of 2.5,...
Source: Acta Cirurgica Brasileira - September 12, 2019 Category: Surgery Authors: Wei D, Xu H, Gai X, Jiang Y Tags: Acta Cir Bras Source Type: research

Bioceramic cement in the filling of bone defects in rats.
CONCLUSION: The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed. PMID: 31432992 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Zerbinatti CC, Veiga DF, Oliveira MAB, Mundim FGL, Pereira RM, Azevedo F, Schnaider TB, Silva Neto JDD Tags: Acta Cir Bras Source Type: research

MiR-106a aggravates sepsis-induced acute kidney injury by targeting THBS2 in mice model.
CONCLUSION: MiR-106a aggravated LPS-induced inflammation and apoptosis of TCMK-1 cells via regulating THBS2 expression. PMID: 31432993 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Shen Y, Yu J, Jing Y, Zhang J Tags: Acta Cir Bras Source Type: research

Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen.
bo MB Abstract PURPOSE: To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats. METHODS: After the defect in the abdominal wall, thirty Wistar rats were placed in three groups (ten animals each) for intraperitoneal mesh implant: polypropylene group, polypropylene/polyglecaprone group, and polyester/porcine collagen group. The macroscopic evaluation of the extent and intensity of adhesions was perfor...
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Ribeiro WG, Rodrigues DVS, Atta FFM, Ramos ISF, Frazão FNS, Torres OJM, Pitombo MB Tags: Acta Cir Bras Source Type: research

Involvement of TLR4 in the protective effect of intra-articular administration of curcumin on rat experimental osteoarthritis.
CONCLUSION: The data suggested that the inhibition of TLR4 signal might be an important mechanism underlying a protective effect of local curcumin administration on OA. PMID: 31432995 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Yan D, He B, Guo J, Li S, Wang J Tags: Acta Cir Bras Source Type: research

Use of derived adipose stem cells to reduce complications of cutaneous scarring in smokers. An experimental model in rats.
Abstract PURPOSE: To evaluate the use of adipose-derived stem cells (ADSC) in reducing the necrosis area in an experimental model of cutaneous ischemic flap in rats submitted to subcutaneous nicotine injection to simulate a smoker patient. METHODS: In an experimental study, 30 rats were enrolled and divided into two experimental groups of 15 animals all submitted to a subcutaneous nicotine injection to create ischemic cutaneous flaps on their backs. Other 10 animals were used only to obtain adipose tissue derived stem cells (ADSC). The first group (n=15) received ADSC treatment at the end of surgery while the...
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Martins JMP, Oliveira FDS, Lima EOC, Dullius D, Durli ICLO, Hiraiwa E, Serrano T, Teixeira GR, Sampaio PMR, Collares MVM Tags: Acta Cir Bras Source Type: research

Pine ( Pinus densiflora ) needle extract could promote the expression of PCNA and Ki-67 after partial hepatectomy in rat.
CONCLUSIONS: Pine needle extract stimulates the expression of some mitotic proteins during liver regeneration induced by 70% PH in rats. It suggests that administration of pine needle extract could accelerate the liver regeneration after partial hepatectomy. PMID: 31432997 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Lee GS, Yang HG, Kim JH, Ahn YM, Han MD, Kim WJ Tags: Acta Cir Bras Source Type: research

Pretreatment of hepatetctomized rats with Coleus forskohlii did not interfere with the course of hepatic hyperplasia.
CONCLUSION: Treatment with Coleus forskohlii did not interfere with the course of hepatic hyperplasia. PMID: 31432998 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Barros PP, Gonçalves GMS, Silva GHD, Fava ALM Tags: Acta Cir Bras Source Type: research

Relaxation incisions and tensile strength in the abdominal wall of pigs.
CONCLUSION: Relaxing incisions reduced tensile strength in the ventral abdominal wall. PMID: 31432999 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Pedroso AR, Melo RM, Oliveira EC Tags: Acta Cir Bras Source Type: research

Glycogen synthase kinase-3 beta inhibitors protectagainst the acute lung injuries resulting from acute necrotizing pancreatitis.
Abstract PURPOSE: The research is intended for clarification of the efficacy as well as the underlying mechanism of GSK-3β inhibitors on the advancement of acute lung injuries in acute necrotizing pancreatitis (ANP) in rats. METHODS: Seventy-two rats were randomly divided into 6 groups: (1)ANP-vehicle; (2)ANP-TDZD-8;(3)ANP-SB216763;(4)Sham-vehicle;(5)Sham-TDZD-8;(6)Sham-SB216763; Blood biochemical test, histopathological examination and immunohistochemical analysis of rats pancreas and lung tissues were performed. The protein expression of GSK-3β, phospho-GSK-3β (Ser9), iNOS, ICAM-1, TNF-&alpha...
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Jin H, Yang X, Zhao K, Zhao L, Chen C, Yu J Tags: Acta Cir Bras Source Type: research

Is the colon mucosa affected by ten days of gastric restriction in an animal model?
CONCLUSION: The colon mucosa is affected by ten days of gastric restriction in an animal model, increasing neutral mucins, acid mucins and collagen content with trophic maintenance. PMID: 31433001 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - August 19, 2019 Category: Surgery Authors: Akamatsu FE, Fontes LG, Itezerote AM, Saleh S, Teodoro WPR, Artifon E, Hojaij F, Andrade M, Pereira JA, Martinez CAR, Jacomo AL Tags: Acta Cir Bras Source Type: research

The application of Compont gel in chronic obstructive jaundice rats model.
CONCLUSION: Intra-biliary injection of Compont gel is different from the classic obstructive jaundice animal model caused by classic bile duct ligation, which can provide an ideal rat model of chronic obstructive jaundice with liver fibrosis. PMID: 31166460 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Luo WW, Zhou XL, Wang QQ, Shao YJ, Li ZM, Zhao DK, Yu SP Tags: Acta Cir Bras Source Type: research

Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion.
CONCLUSION: The pharmacological modulation of β-AR could be a new cardioprotective strategy for the therapy of myocardial dysfunctions induced by CIR related to cardiac surgery and cardiovascular diseases. PMID: 31166461 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Menezes-Rodrigues FS, Errante PR, Tavares JGP, Ferraz RRN, Gomes WJ, Taha MO, Scorza CA, Scorza FA, Caricati-Neto A Tags: Acta Cir Bras Source Type: research

Muscle changes with high-intensity aerobic training in an animal model of renal disease.
CONCLUSION: HIAT in an animal model of RD resulted in increased the number of muscle fibers with smaller CSA. PMID: 31166462 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Togoe EB, Silva IS, Cury JL, Guarnier FA Tags: Acta Cir Bras Source Type: research

Inhibitory effect of Astragalus polysaccharide on osteoporosis in ovariectomized rats by regulating FoxO3a /Wnt signaling pathway.
CONCLUSION: Astragalus polysaccharide can effectively alleviate oxidative stress-mediated osteoporosis in ovariectomized rats, which may be related to its regulation of FoxO3a/Wnt2/β-catenin pathway. PMID: 31166463 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Ou L, Wei P, Li M, Gao F Tags: Acta Cir Bras Source Type: research

The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia-reperfusion injury.
CONCLUSION: Ischemic preconditioning protect rat small intestine against ischemia/reperfusion injury, reducing morphologic lesions and apoptosis. PMID: 31166464 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Miranda CTCBC, Fagundes DJ, Miranda E, Simões RS, Carbonel AAF, Florencio-Silva R, Taha MO Tags: Acta Cir Bras Source Type: research

Analysis of inflammatory and metabolic biomarkers in patients submitted to abdominoplasty after bariatric surgery.
CONCLUSION: The inflammatory and glycemic serum levels decrease after abdominiplasty in obese post-bariatric patients. PMID: 31166465 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - June 7, 2019 Category: Surgery Authors: Modolin MLA, Cintra W, Rocha RI, Camargo CP, Giuliani NR, Souza HP, Barbeiro HV, Gemperli R Tags: Acta Cir Bras Source Type: research

Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy.
Abstract PURPOSE: To investigate the relations of neuropeptide Y (NPY) and heme oxygenase-1 (HO-1) expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy (ICP). METHODS: Sixty rats pregnant for 15 days were randomly divided into experimental and control groups. The ICP model was established in experimental group. On the 21st day, the blood biochemical test, histopathological examination of pregnant rat liver and fetal brain tissues and immunohistochemical analysis of fetal rat brain tissues were performed. RESULTS: On the 21st day, the alanineaminotransferase, aspartate am...
Source: Acta Cirurgica Brasileira - May 6, 2019 Category: Surgery Authors: Li H, Liu B, Gu C, Zeng X, Liu Y, Zhang S, Gong H, Shao Y, Yao Z, An R Tags: Acta Cir Bras Source Type: research

Effect of taxifolin on oxidative gastric injury induced by celiac artery ligation in rats.
CONCLUSION: The taxifolin can be clinically beneficial in the treatment of gastric injury due to I/R procedure. PMID: 31066786 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - May 6, 2019 Category: Surgery Authors: Eken H, Cimen O, Cimen FK, Kurnaz E, Yildirim M, Tasova V, Kurt N, Pehlivanoglu K, Onk D, Bilgin AO Tags: Acta Cir Bras Source Type: research

Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats.
CONCLUSIONS: The omega-6/3 and omega-9/6 nutraceuticals decreased pain compared to the controls. There was no improvement in fertility in any of the tested groups. PMID: 31066787 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - May 6, 2019 Category: Surgery Authors: Pereira FEXG, Medeiros FDC, Rocha HAL, Silva KSD Tags: Acta Cir Bras Source Type: research

The effect of graft application and simvastatin treatment on tibial bone defect in rats. A histological and immunohistochemical study.
CONCLUSION: The simvastatin application was thought to increase bone turnover by increasing the osteoinductive effect with graft and significantly affect the formation of new bone. PMID: 31066788 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - May 6, 2019 Category: Surgery Authors: Laçin N, İzol BS, Özkorkmaz EG, Deveci B, Tuncer MC Tags: Acta Cir Bras Source Type: research

Erratum.
Authors: Abstract [This corrects the article doi: 10.1590/s0102-865020190010000009]. PMID: 31066789 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - May 6, 2019 Category: Surgery Tags: Acta Cir Bras Source Type: research

A new organ preservation solution for static cold storage of the liver. Amniotic fluid.
CONCLUSIONS: AF provided conservation similar to UW and HTK in the 12-hour liver SCS process. The fact that apoptosis values are comparable to standard preservation solutions supports the success of AF in the cold storage of the liver. PMID: 31038582 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Büyük B, Demirci T, Adalı Y, Eroğlu HA Tags: Acta Cir Bras Source Type: research

Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model.
Abstract PURPOSE: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. METHODS: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of selected lncRNAs and mRNAs.The potential functions of the lncRNA was analyzed by bioinformatics tools and databases. RESULTS: Kidney function was impaired in I/R group compared to the normal group. Analysis showed that a total of 2267 lncRNAs and 2341 me...
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Tao Q, Tianyu W, Jiangqiao Z, Zhongbao C, Xiaoxiong M, Long Z, Jilin Z Tags: Acta Cir Bras Source Type: research

Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream.
CONCLUSION: Mesalazine enemas reduce the inflammatory process and preserve the content of mucins in colonic mucosa devoid of fecal stream. PMID: 31038584 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Martinez CAR, Campos FG, Kanno DT, Meneses EC, Matijascic GM, Goto EFK, Pereira JA Tags: Acta Cir Bras Source Type: research

Oxidative stress assessment in intestine of newborn rats submitted to hypoxia and reoxygenation with tadalafil.
CONCLUSION: Tadalafil provides tissue protection when administered independently to both, pregnant or newborns. PMID: 31038585 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Teixeira LC, Fujiki RTM, Souza CVCP, Souza CM, Mismetti MM, Artigiane-Neto R, Montero EFS, Martins JL Tags: Acta Cir Bras Source Type: research

Relationship between serum MMP-9 level and prognosis after radical resection for Hilar cholangiocarcinoma patients.
CONCLUSION: Preoperative serum MMP-9 has high predictive value for prognosis and is an independent influencing factor for the prognosis of patients with hilar cholangiocarcinoma. PMID: 31038586 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Li O, Yi W, Yang P, Guo C, Peng C Tags: Acta Cir Bras Source Type: research

The alternative model of silicone for experimental simulation of suture of living tissue in the teaching of surgical technique.
CONCLUSIONS: The model developed for experimental simulation of tissue sutures has proved to be a fully feasible alternative method for the training of this surgical skill. It is a simple, reproducible and low-cost model. PMID: 31038587 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - April 29, 2019 Category: Surgery Authors: Silva APGD, Rodriguez JER, Oliveira MC, Negreiros RMA, Cavalcante LP Tags: Acta Cir Bras Source Type: research

Videothermometry to evaluate metabolic activity in real time during pneumectomy in rats.
Abstract PURPOSE: To evaluate, in rats, the open field videothermometry in real time while performing left pneumonectomy for early diagnosis of cardiopulmonary changes. METHODS: Twelve non-specific pathogen-free Wistar rats were randomly allocated into two groups; pneumectomy group (GP) and sham surgery group (GS). Mean arterial pressure, videothermometry in real time, of the right lung, and histopathological analysis of the remaining lung were evaluated in all animals. RESULTS: Videothermometry in real time allowed identification of temperature variance of right lung after pneumectomy, indicating a sign...
Source: Acta Cirurgica Brasileira - March 21, 2019 Category: Surgery Authors: Vidal LWM, Cabral PGA, Santos Junior MBD, Antunes F, Mota MRD, Silva TOBD, Monteiro GAS, Scheffer JP, Ribeiro MDS, Oliveira ALA Tags: Acta Cir Bras Source Type: research

The role of high sensitive C-reactive protein and histopathological evaluation in chronic gastritis patients with or without Helicobacter pylori infection.
CONCLUSION: Serum hs-CRP level increases in patients with chronic gastritis, it could be an indicator of severity of acute or chronic mucosal inflammation, and presence of HP infection. Therefore, hs-CRP may aid the diagnosis of chronic gastritis, but it is not associated with pre-cancerous lesions. PMID: 30916140 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - March 21, 2019 Category: Surgery Authors: Altun E, Yildiz A, Cevik C, Turan G Tags: Acta Cir Bras Source Type: research

Undernutrition impairs the quality of growth plate and trabecular and cortical bones in growing rats1.
CONCLUSION: Dietary restriction had severe detrimental effects on the growth plate and trabecular and cortical bone. PMID: 30892388 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - March 18, 2019 Category: Surgery Authors: Guedes PMSG, Zamarioli A, Botega II, Silva RABD, Issa JPM, Butezloff MM, Sousa YTCS, Ximenez JPB, Volpon JB Tags: Acta Cir Bras Source Type: research

New determinants for casual peripheral mechanism of neurogenic lung edema in subarachnoid hemorrhage due to ischemic degeneration of vagal nerve, kidney and lung circuitry. Experimental study1.
This study was conducted on 26 rabbits. A control group was formed of five animals, a SHAM group of 5 to which saline and a study group (n=16) injected with homologous blood into the sylvian cisterna. Numbers of degenerated axons of renal branches of vagal nerves, atrophic glomerulus numbers and NLE scores were recorded. RESULTS: Important vagal degeneration, severe renal artery vasospasm, intrarenal hemorrhage and glomerular atrophy observed in high score NLE detected animals. The mean degenerated axon density of vagal nerves (n/mm2), atrophic glomerulus density (n/mm3) and NLE scores of control, SHAM and study group...
Source: Acta Cirurgica Brasileira - March 18, 2019 Category: Surgery Authors: Soyalp C, Kocak MN, Ahiskalioglu A, Aksoy M, Atalay C, Aydin MD, Cakir M, Calikoglu C, Ozmen S Tags: Acta Cir Bras Source Type: research

Does the type of electrode affect the electromyoneurographic parameters in rats?1.
CONCLUSION: The type of electrode does not affect the electroneuromyography parameters. PMID: 30892390 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - March 18, 2019 Category: Surgery Authors: Somensi DN, Teixeira RKC, Feijó DH, Loureiro KD, Valente AL, Carvalho LTF, Calvo FC, Santos DRD, Barros RSM Tags: Acta Cir Bras Source Type: research

Effect of ethyl acetate extract of usnea longissima on esophagogastric adenocarcinoma in rats1.
CONCLUSION: This information may shed light on clinical implementation of EtOAc extract of U. longissima in future. PMID: 30892391 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - March 18, 2019 Category: Surgery Authors: Mammadov R, Suleyman B, Altuner D, Demirci E, Cetin N, Yilmaz A, Baykal H, Alpcan H, Turumtay EA, Suleyman H Tags: Acta Cir Bras Source Type: research