The impact of long- and short-term exposure to different ambient air pollutants on cognitive function in China
Environ Int. 2021 Mar 2;151:106416. doi: 10.1016/j.envint.2021.106416. Online ahead of print.ABSTRACTIn the field of environmental health, the impact of air pollution on people's cognitive function is receiving increasing attention. Various air pollution exposures and different exposure periods result in different degrees of damage to cognition. This paper first used CFPS cognitive tests to evaluate the cognitive function of 15,163 adults in 25 provinces of China. Next, based on the geographical location of the population, the kriging interpolation method was applied to evaluate the different exposure periods for various a...
Source: Environment International - March 5, 2021 Category: Environmental Health Authors: Huaxi Gao Jieran Shi Hongguang Cheng Yaqin Zhang Yan Zhang Source Type: research

Foetal 25-hydroxyvitamin D moderates the association of prenatal air pollution exposure with foetal glucolipid metabolism disorder and systemic inflammatory responses
Environ Int. 2021 Mar 1;151:106460. doi: 10.1016/j.envint.2021.106460. Online ahead of print.ABSTRACTBACKGROUND: Previous studies have indicated that systemic inflammation may play an important role in the association between air pollution exposure and glucolipid metabolism disorders, and vitamin D supplementation was beneficial in improving systemic inflammation and glucolipid metabolism. However, the role of foetal 25-hydroxyvitamin D (25(OH)D) and high-sensitivity C-reactive protein (hs-CRP) in the association between prenatal air pollution exposure and foetal glucolipid metabolism disorders is still not clear.OBJECTIVE...
Source: Environment International - March 4, 2021 Category: Environmental Health Authors: Yang Liu Lei Li Jun Xie Xuechun Jiao Honglin Hu Ying Zhang Ruixue Tao Fangbiao Tao Peng Zhu Source Type: research

Discovering hidden spatial patterns and their associations with controlling factors for potentially toxic elements in topsoil using hot spot analysis and K-means clustering analysis
This study demonstrates the power of spatial machine learning techniques in identifying hidden spatial patterns, providing evidences to extract geochemical knowledge in environmental studies.PMID:33662887 | DOI:10.1016/j.envint.2021.106456 (Source: Environment International)
Source: Environment International - March 4, 2021 Category: Environmental Health Authors: Haofan Xu Peter Croot Chaosheng Zhang Source Type: research

Foetal 25-hydroxyvitamin D moderates the association of prenatal air pollution exposure with foetal glucolipid metabolism disorder and systemic inflammatory responses
Environ Int. 2021 Mar 1;151:106460. doi: 10.1016/j.envint.2021.106460. Online ahead of print.ABSTRACTBACKGROUND: Previous studies have indicated that systemic inflammation may play an important role in the association between air pollution exposure and glucolipid metabolism disorders, and vitamin D supplementation was beneficial in improving systemic inflammation and glucolipid metabolism. However, the role of foetal 25-hydroxyvitamin D (25(OH)D) and high-sensitivity C-reactive protein (hs-CRP) in the association between prenatal air pollution exposure and foetal glucolipid metabolism disorders is still not clear.OBJECTIVE...
Source: Environment International - March 4, 2021 Category: Environmental Health Authors: Yang Liu Lei Li Jun Xie Xuechun Jiao Honglin Hu Ying Zhang Ruixue Tao Fangbiao Tao Peng Zhu Source Type: research

Discovering hidden spatial patterns and their associations with controlling factors for potentially toxic elements in topsoil using hot spot analysis and K-means clustering analysis
This study demonstrates the power of spatial machine learning techniques in identifying hidden spatial patterns, providing evidences to extract geochemical knowledge in environmental studies.PMID:33662887 | DOI:10.1016/j.envint.2021.106456 (Source: Environment International)
Source: Environment International - March 4, 2021 Category: Environmental Health Authors: Haofan Xu Peter Croot Chaosheng Zhang Source Type: research

Residence characteristics and risk of nasopharyngeal carcinoma in southern China: A population-based case-control study
CONCLUSION: Poorer residential conditions and household air pollution are associated with an increased risk of NPC. Large-scale studies in other populations or longitudinal studies are warranted to further corroborate these findings.PMID:33652252 | DOI:10.1016/j.envint.2021.106455 (Source: Environment International)
Source: Environment International - March 2, 2021 Category: Environmental Health Authors: Yufeng Chen Ellen T Chang Zhiwei Liu Qing Liu Yonglin Cai Zhe Zhang Guomin Chen Qi-Hong Huang Shang-Hang Xie Su-Mei Cao Wei-Hua Jia Yuming Zheng Yancheng Li Longde Lin Ingemar Ernberg Hongwei Zhao Ruimei Feng Guangwu Huang Yi Zeng Yi-Xin Zeng Hans-Olov Ad Source Type: research

Residence characteristics and risk of nasopharyngeal carcinoma in southern China: A population-based case-control study
CONCLUSION: Poorer residential conditions and household air pollution are associated with an increased risk of NPC. Large-scale studies in other populations or longitudinal studies are warranted to further corroborate these findings.PMID:33652252 | DOI:10.1016/j.envint.2021.106455 (Source: Environment International)
Source: Environment International - March 2, 2021 Category: Environmental Health Authors: Yufeng Chen Ellen T Chang Zhiwei Liu Qing Liu Yonglin Cai Zhe Zhang Guomin Chen Qi-Hong Huang Shang-Hang Xie Su-Mei Cao Wei-Hua Jia Yuming Zheng Yancheng Li Longde Lin Ingemar Ernberg Hongwei Zhao Ruimei Feng Guangwu Huang Yi Zeng Yi-Xin Zeng Hans-Olov Ad Source Type: research

Mechanisms for tissue-specific accumulation and phase I/II transformation of 6:2 fluorotelomer phosphate diester in earthworm (M. guillelmi)
Environ Int. 2021 Feb 26;151:106451. doi: 10.1016/j.envint.2021.106451. Online ahead of print.ABSTRACTPolyfluoroalkyl phosphate esters (PAPs) are high production volume surfactants used in the food contact paper and packaging industries. They are prone to partition to soil due to their strong hydrophobicity and may biotransform into recalcitrant perfluoroalkyl carboxylic acids (PFCAs); little is known about their fate and behaviors in terrestrial organisms. Here, geophagous earthworms (M. guillelmi) were exposed to 6:2 fluorotelomer phosphate diester (6:2 diPAP)-contaminated soil to examine tissue-specific accumulation and...
Source: Environment International - March 1, 2021 Category: Environmental Health Authors: Yumin Zhu Yibo Jia Menglin Liu Liping Yang Shujun Yi Xuemin Feng Lingyan Zhu Source Type: research

Greening is a promising but likely insufficient adaptation strategy to limit the health impacts of extreme heat
DISCUSSION: A lack of vegetation and a high degree of imperviousness were associated with a higher risk of heat-related mortality in the Paris region. Therefore, we can assume that interventions targeting these characteristics could reduce the health impacts of extreme heat. Such interventions should be coupled with other initiatives such as protecting the most vulnerable and promoting appropriate behaviors.PMID:33640693 | DOI:10.1016/j.envint.2021.106441 (Source: Environment International)
Source: Environment International - February 28, 2021 Category: Environmental Health Authors: Mathilde Pascal Sarah Goria V érène Wagner Marine Sabastia Agn ès Guillet Erwan Cordeau C écile Mauclair Sabine Host Source Type: research

Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth
CONCLUSION: In this prospective cohort of subfertile couples, maternal BPA and DEHP, and paternal DEHP exposure before conception were positively associated with preterm birth. Both parental windows jointly contributed to the outcome. These results suggest that preterm birth may be a couple-based pregnancy outcome.PMID:33640694 | DOI:10.1016/j.envint.2021.106440 (Source: Environment International)
Source: Environment International - February 28, 2021 Category: Environmental Health Authors: Yu Zhang Vicente Mustieles Paige L Williams Blair J Wylie Irene Souter Antonia M Calafat Melina Demokritou Alexandria Lee Stylianos Vagios Russ Hauser Carmen Messerlian Source Type: research

Greening is a promising but likely insufficient adaptation strategy to limit the health impacts of extreme heat
DISCUSSION: A lack of vegetation and a high degree of imperviousness were associated with a higher risk of heat-related mortality in the Paris region. Therefore, we can assume that interventions targeting these characteristics could reduce the health impacts of extreme heat. Such interventions should be coupled with other initiatives such as protecting the most vulnerable and promoting appropriate behaviors.PMID:33640693 | DOI:10.1016/j.envint.2021.106441 (Source: Environment International)
Source: Environment International - February 28, 2021 Category: Environmental Health Authors: Mathilde Pascal Sarah Goria V érène Wagner Marine Sabastia Agn ès Guillet Erwan Cordeau C écile Mauclair Sabine Host Source Type: research

Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth
CONCLUSION: In this prospective cohort of subfertile couples, maternal BPA and DEHP, and paternal DEHP exposure before conception were positively associated with preterm birth. Both parental windows jointly contributed to the outcome. These results suggest that preterm birth may be a couple-based pregnancy outcome.PMID:33640694 | DOI:10.1016/j.envint.2021.106440 (Source: Environment International)
Source: Environment International - February 28, 2021 Category: Environmental Health Authors: Yu Zhang Vicente Mustieles Paige L Williams Blair J Wylie Irene Souter Antonia M Calafat Melina Demokritou Alexandria Lee Stylianos Vagios Russ Hauser Carmen Messerlian Source Type: research

Prenatal exposure to bisphenols and cognitive function in children at 7  years of age in the Swedish SELMA study
DISCUSSION: Prenatal exposure to BPF was significantly associated with childreńs cognitive function at 7 years. Since BPF is replacing BPA in numerous consumer products globally, this finding urgently call for further studies.PMID:33637302 | DOI:10.1016/j.envint.2021.106433 (Source: Environment International)
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Carl-Gustaf Bornehag Elin Engdahl Maria Unenge Hallerb äck Sverre Wikstr öm Christian Lindh Jo ëlle Rüegg Eva Tanner Chris Gennings Source Type: research

Size-dependent adverse effects of microplastics on intestinal microbiota and metabolic homeostasis in the marine medaka (Oryzias melastigma)
In this study, adult marine medaka (Oryzias melastigma) were exposed to different size of polystyrene MPs (PS-MPs) with concentration of 10 mg/L for 60 days and the growth performance, lipid metabolism, immune parameters and gut microbiome were determined. Results indicated that particle size is a dominant factor causing lipid metabolism disorders and hepatic toxicity in PS-MPs-exposed fish. The bodyweight, adipocyte size and hepatic lipid contents were significantly increased in 200 μm PS-MPs-exposed fish, while 2 and 10 μm PS-MPs-exposed fish exhibited liver injury principally manifested asthepresence oflittlefibro...
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Xu Zhang Kai Wen Dongxiao Ding Jintao Liu Zhao Lei Xiaoxuan Chen Guozhu Ye Jie Zhang Heqing Shen Changzhou Yan Sijun Dong Qiansheng Huang Yi Lin Source Type: research

Ambient PM < sub > 2.5 < /sub > species and ultrafine particle exposure and their differential metabolomic signatures
Environ Int. 2021 Feb 24;151:106447. doi: 10.1016/j.envint.2021.106447. Online ahead of print.ABSTRACTBACKGROUND: The metabolomic signatures of short- and long-term exposure to PM2.5 have been reported and linked to inflammation and oxidative stress. However, little is known about the relative contribution of the specific PM2.5 species (hence sources) that drive these metabolomic signatures.OBJECTIVES: We aimed to determine the relative contribution of the different species of PM2.5 exposure to the perturbed metabolic pathways related to changes in the plasma metabolome.METHODS: We performed mass-spectrometry based metabol...
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Feiby L Nassan Cuicui Wang Rachel S Kelly Jessica A Lasky-Su Pantel S Vokonas Petros Koutrakis Joel D Schwartz Source Type: research

Prenatal exposure to bisphenols and cognitive function in children at 7  years of age in the Swedish SELMA study
DISCUSSION: Prenatal exposure to BPF was significantly associated with childreńs cognitive function at 7 years. Since BPF is replacing BPA in numerous consumer products globally, this finding urgently call for further studies.PMID:33637302 | DOI:10.1016/j.envint.2021.106433 (Source: Environment International)
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Carl-Gustaf Bornehag Elin Engdahl Maria Unenge Hallerb äck Sverre Wikstr öm Christian Lindh Jo ëlle Rüegg Eva Tanner Chris Gennings Source Type: research

Size-dependent adverse effects of microplastics on intestinal microbiota and metabolic homeostasis in the marine medaka (Oryzias melastigma)
In this study, adult marine medaka (Oryzias melastigma) were exposed to different size of polystyrene MPs (PS-MPs) with concentration of 10 mg/L for 60 days and the growth performance, lipid metabolism, immune parameters and gut microbiome were determined. Results indicated that particle size is a dominant factor causing lipid metabolism disorders and hepatic toxicity in PS-MPs-exposed fish. The bodyweight, adipocyte size and hepatic lipid contents were significantly increased in 200 μm PS-MPs-exposed fish, while 2 and 10 μm PS-MPs-exposed fish exhibited liver injury principally manifested asthepresence oflittlefibro...
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Xu Zhang Kai Wen Dongxiao Ding Jintao Liu Zhao Lei Xiaoxuan Chen Guozhu Ye Jie Zhang Heqing Shen Changzhou Yan Sijun Dong Qiansheng Huang Yi Lin Source Type: research

Ambient PM < sub > 2.5 < /sub > species and ultrafine particle exposure and their differential metabolomic signatures
Environ Int. 2021 Feb 24;151:106447. doi: 10.1016/j.envint.2021.106447. Online ahead of print.ABSTRACTBACKGROUND: The metabolomic signatures of short- and long-term exposure to PM2.5 have been reported and linked to inflammation and oxidative stress. However, little is known about the relative contribution of the specific PM2.5 species (hence sources) that drive these metabolomic signatures.OBJECTIVES: We aimed to determine the relative contribution of the different species of PM2.5 exposure to the perturbed metabolic pathways related to changes in the plasma metabolome.METHODS: We performed mass-spectrometry based metabol...
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Feiby L Nassan Cuicui Wang Rachel S Kelly Jessica A Lasky-Su Pantel S Vokonas Petros Koutrakis Joel D Schwartz Source Type: research

Prenatal exposure to bisphenols and cognitive function in children at 7  years of age in the Swedish SELMA study
DISCUSSION: Prenatal exposure to BPF was significantly associated with childreńs cognitive function at 7 years. Since BPF is replacing BPA in numerous consumer products globally, this finding urgently call for further studies.PMID:33637302 | DOI:10.1016/j.envint.2021.106433 (Source: Environment International)
Source: Environment International - February 27, 2021 Category: Environmental Health Authors: Carl-Gustaf Bornehag Elin Engdahl Maria Unenge Hallerb äck Sverre Wikstr öm Christian Lindh Jo ëlle Rüegg Eva Tanner Chris Gennings Source Type: research

A new LC/MS method for specific determination of human systemic exposure to bisphenol A, F and S through their metabolites: Application to cord blood samples
Environ Int. 2021 Feb 23;151:106429. doi: 10.1016/j.envint.2021.106429. Online ahead of print.ABSTRACTDue to restriction of the use of BPA, several structural analogues such as BPS and BPF have been proposed for its replacement in many consumer products. This has increased the prevalence of BPS and BPF in urine from tested cohorts. However, these substitutes have similar endocrine disrupting properties to BPA, particularly on reproductive and metabolic functions, which suggests that fetal exposure to these analogues could be of concern for human health. Bisphenols (BPs) are mainly metabolized to glucuronides (BP-Gs), which...
Source: Environment International - February 26, 2021 Category: Environmental Health Authors: C A G ély A Huesca N Picard-Hagen P L Toutain A Berrebi G Gauderat V Gayrard M Z Lacroix Source Type: research

Per- and polyfluoroalkyl substances and calcifications of the coronary and aortic arteries in adults with prediabetes: Results from the diabetes prevention program outcomes study
CONCLUSIONS: Prediabetic adults with higher plasma concentrations of select PFAS had higher risk of coronary and thoracic aorta calcification. PFAS exposure may be a risk factor for adverse cardiovascular health among high-risk populations.PMID:33631604 | DOI:10.1016/j.envint.2021.106446 (Source: Environment International)
Source: Environment International - February 25, 2021 Category: Environmental Health Authors: Citlalli Osorio-Y áñez Marco Sanchez-Guerra Andres Cardenas Pi-I D Lin Russ Hauser Diane R Gold Ken P Kleinman Marie-France Hivert Abby F Fleisch Antonia M Calafat Thomas F Webster Edward S Horton Emily Oken Source Type: research

Fouling potentials and properties of foulants in an innovative algal-sludge membrane bioreactor
This study focused on the effect of algae on the fouling potential and dynamic fouling variation of foulants in an innovative algal-sludge membrane bioreactor (AS-MBR). Filtration experiments revealed that the soluble extracellular polymeric substance (S-EPS) released by the algal-sludge flocs showed a slower diminishing rate of flux than that released by the sludge flocs. The intermediate blocking and cake filtration models demonstrated the major mechanisms, which implied a reduction in the driving force of pore blocking and fouling layer formation induced by the algal-bacterial S-EPS. Furthermore, the relative flux decre...
Source: Environment International - February 24, 2021 Category: Environmental Health Authors: Li Sun Yu Tian Hui Li Qiong Wang Source Type: research

Towards guidelines for time-trend reviews examining temporal variability in human biomonitoring data of pollutants
In this study, we therefore present a proposal for guidelines to conduct "time-trend reviews" (TTRs) that examine time trends in published large HBM datasets of chemical pollutant concentrations. We also demonstrate the applicability of these guidelines through a case study that assesses time-trends in global and regional HBM data on mercury. The recommended TTR guidelines in this study are divided into seven steps: formulating the objective of the TTR, setting up of eligibility criteria, defining search strategy and screening of literature, screening results of search, extracting data, analysing data, and assess...
Source: Environment International - February 24, 2021 Category: Environmental Health Authors: Brij Mohan Sharma Ji ří Kalina Paul Whaley Martin Scheringer Source Type: research

Fouling potentials and properties of foulants in an innovative algal-sludge membrane bioreactor
This study focused on the effect of algae on the fouling potential and dynamic fouling variation of foulants in an innovative algal-sludge membrane bioreactor (AS-MBR). Filtration experiments revealed that the soluble extracellular polymeric substance (S-EPS) released by the algal-sludge flocs showed a slower diminishing rate of flux than that released by the sludge flocs. The intermediate blocking and cake filtration models demonstrated the major mechanisms, which implied a reduction in the driving force of pore blocking and fouling layer formation induced by the algal-bacterial S-EPS. Furthermore, the relative flux decre...
Source: Environment International - February 24, 2021 Category: Environmental Health Authors: Li Sun Yu Tian Hui Li Qiong Wang Source Type: research

Towards guidelines for time-trend reviews examining temporal variability in human biomonitoring data of pollutants
In this study, we therefore present a proposal for guidelines to conduct "time-trend reviews" (TTRs) that examine time trends in published large HBM datasets of chemical pollutant concentrations. We also demonstrate the applicability of these guidelines through a case study that assesses time-trends in global and regional HBM data on mercury. The recommended TTR guidelines in this study are divided into seven steps: formulating the objective of the TTR, setting up of eligibility criteria, defining search strategy and screening of literature, screening results of search, extracting data, analysing data, and assess...
Source: Environment International - February 24, 2021 Category: Environmental Health Authors: Brij Mohan Sharma Ji ří Kalina Paul Whaley Martin Scheringer Source Type: research

A global overview of the trophic structure within microbiomes across ecosystems
Environ Int. 2021 Feb 20;151:106438. doi: 10.1016/j.envint.2021.106438. Online ahead of print.ABSTRACTThe colossal project of mapping the microbiome on Earth is rapidly advancing, with a focus on individual microbial groups. However, a global assessment of the associations between predatory protists and their bacterial prey is still missing at a cross-ecosystem level. This knowledge is critical to better understand the importance of top-down links in structuring microbiomes. Here, we examined 38 sequence-based datasets of paired bacterial and protistan taxa, covering 3,178 samples from diverse habitats including freshwater...
Source: Environment International - February 23, 2021 Category: Environmental Health Authors: Wu Xiong Alexandre Jousset Rong Li Manuel Delgado-Baquerizo Mohammad Bahram Ramiro Logares Benjamin Wilden Gerard Arjen de Groot Nathalie Amacker George A Kowalchuk Qirong Shen Stefan Geisen Source Type: research

Antibiotic exposure decreases soil arsenic oral bioavailability in mice by disrupting ileal microbiota and metabolic profile
Environ Int. 2021 Feb 20;151:106444. doi: 10.1016/j.envint.2021.106444. Online ahead of print.ABSTRACTOral bioavailability of arsenic (As) determines levels of As exposure via ingestion of As-contaminated soil, however, the role of gut microbiota in As bioavailability has not evaluated in vivo although some in vitro studies have investigated this. Here, we made a comparison in As relative bioavailability (RBA) estimates for a contaminated soil (3913 mg As kg-1) using a mouse model with and without penicillin perturbing gut microbiota and metabolites. Compared to soil exposure alone (2% w/w soil in diets), addition of penic...
Source: Environment International - February 23, 2021 Category: Environmental Health Authors: Meng-Ya Li Xiao-Qiang Chen Jue-Yang Wang Hong-Tao Wang Xi-Mei Xue Jing Ding Albert L Juhasz Yong-Guan Zhu Hong-Bo Li Lena Q Ma Source Type: research

A global overview of the trophic structure within microbiomes across ecosystems
Environ Int. 2021 Feb 20;151:106438. doi: 10.1016/j.envint.2021.106438. Online ahead of print.ABSTRACTThe colossal project of mapping the microbiome on Earth is rapidly advancing, with a focus on individual microbial groups. However, a global assessment of the associations between predatory protists and their bacterial prey is still missing at a cross-ecosystem level. This knowledge is critical to better understand the importance of top-down links in structuring microbiomes. Here, we examined 38 sequence-based datasets of paired bacterial and protistan taxa, covering 3,178 samples from diverse habitats including freshwater...
Source: Environment International - February 23, 2021 Category: Environmental Health Authors: Wu Xiong Alexandre Jousset Rong Li Manuel Delgado-Baquerizo Mohammad Bahram Ramiro Logares Benjamin Wilden Gerard Arjen de Groot Nathalie Amacker George A Kowalchuk Qirong Shen Stefan Geisen Source Type: research

Antibiotic exposure decreases soil arsenic oral bioavailability in mice by disrupting ileal microbiota and metabolic profile
Environ Int. 2021 Feb 20;151:106444. doi: 10.1016/j.envint.2021.106444. Online ahead of print.ABSTRACTOral bioavailability of arsenic (As) determines levels of As exposure via ingestion of As-contaminated soil, however, the role of gut microbiota in As bioavailability has not evaluated in vivo although some in vitro studies have investigated this. Here, we made a comparison in As relative bioavailability (RBA) estimates for a contaminated soil (3913 mg As kg-1) using a mouse model with and without penicillin perturbing gut microbiota and metabolites. Compared to soil exposure alone (2% w/w soil in diets), addition of penic...
Source: Environment International - February 23, 2021 Category: Environmental Health Authors: Meng-Ya Li Xiao-Qiang Chen Jue-Yang Wang Hong-Tao Wang Xi-Mei Xue Jing Ding Albert L Juhasz Yong-Guan Zhu Hong-Bo Li Lena Q Ma Source Type: research

The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury
Environ Int. 2021 Feb 18:106387. doi: 10.1016/j.envint.2021.106387. Online ahead of print.ABSTRACTBACKGROUND: The World Health Organization (WHO) and the International Labour Organization (ILO) are developing joint estimates of the work-related burden of disease and injury (WHO/ILO Joint Estimates), with contributions from a large number of individual experts. Evidence from mechanistic data suggests that occupational exposure to noise may cause cardiovascular disease (CVD). In this paper, we present a systematic review and meta-analysis of parameters for estimating the number of deaths and disability-adjusted life years fr...
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Liliane R Teixeira Frank Pega Angel M Dzhambov Alicja Bortkiewicz Denise T Correa da Silva Carlos A F de Andrade Elzbieta Gadzicka Kishor Hadkhale Sergio Iavicoli Martha S Mart ínez-Silveira Ma łgorzata Pawlaczyk-Łuszczyńska Bruna M Rondinone Jadwiga Source Type: research

Corrigendum to "The environmental impacts and the carbon intensity of geothermal energy: A case study on the Hellishei ði plant" [Environ. Int. 133(Part B) (2019) 105226]
Environ Int. 2021 Feb 19;151:106432. doi: 10.1016/j.envint.2021.106432. Online ahead of print.NO ABSTRACTPMID:33618326 | DOI:10.1016/j.envint.2021.106432 (Source: Environment International)
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Andrea Paulillo Aberto Striolo Paola Lettieri Source Type: research

Early occupational exposure to lead on neutrophil-to-lymphocyte ratio and genotoxicity
Environ Int. 2021 Feb 19;151:106448. doi: 10.1016/j.envint.2021.106448. Online ahead of print.ABSTRACTBACKGROUND: Lead (Pb) is known to induce detrimental health effects in exposed populations, including hematotoxicity and genotoxicity. Complete blood count (CBC) is a cost-effective and easy way to determine toxicity, and variations in proportion of different types of leukocytes: neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) are further evidence of hematotoxicity. However, few studies have been conducted to systematically evaluate effects of occupational Pb exposure on NLR and LMR, and their a...
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Yu Meng Kan Wang Tuanwei Wang Yuting Tu Shiyang Gong Yunxia Zhang Guanghui Zhang William Au David C Christiani Zhao-Lin Xia Source Type: research

Estimation of ambient PM < sub > 2.5 < /sub > in Iraq and Kuwait from 2001 to 2018 using machine learning and remote sensing
Environ Int. 2021 Feb 19;151:106445. doi: 10.1016/j.envint.2021.106445. Online ahead of print.ABSTRACTIraq and Kuwait are in a region of the world known to be impacted by high levels of fine particulate matter (PM2.5) attributable to sources that include desert dust and ambient pollution, but historically have had limited pollution monitoring networks. The inability to assess PM2.5 concentrations have limited the assessment of the health impact of these exposures, both in the native populations and previously deployed military personnel. As part of a Department of Veterans Affairs Cooperative Studies Program health study o...
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Jing Li Eric Garshick Jaime E Hart Longxiang Li Liuhua Shi Ali Al-Hemoud Shaodan Huang Petros Koutrakis Source Type: research

Wood emissions and asthma development: Results from an experimental mouse model and a prospective cohort study
CONCLUSION: Our findings indicate that emissions from wood and wood products at levels commonly occurring in the living environment do not exert adverse effects concerning wheezing or asthma development.PMID:33611105 | DOI:10.1016/j.envint.2021.106449 (Source: Environment International)
Source: Environment International - February 21, 2021 Category: Environmental Health Authors: Kristin M Junge Lisa Buchenauer Elena Elter Katja Butter Tibor Kohajda Gunda Herberth Stefan R öder Michael Borte Wieland Kiess Martin von Bergen Jan C Simon Ulrike E Rolle-Kampczyk Irina Lehmann Richard Gminski Martin Ohlmeyer Tobias Polte Source Type: research

Sustained bloodstream release of persistent organic pollutants induced by extensive weight loss after bariatric surgery: Implications for women of childbearing age
DISCUSSION: Massive weight loss within the first year following bariatric surgery is associated with a sustained increase of circulating lipophilic POPs. Short- and long-term consequences should be considered, mostly for childbearing age obese women, because of potential health risks for the future fetus and breastfeeding infant.PMID:33611106 | DOI:10.1016/j.envint.2021.106400 (Source: Environment International)
Source: Environment International - February 21, 2021 Category: Environmental Health Authors: Patrick F énichel Patrick Coquillard Fran çoise Brucker-Davis Philippe Marchand German Cano-Sancho Mireille Boda Jean-Philippe Antignac Antonio Iannelli Jean Gugenheim Bruno Le Bizec Nicolas Chevalier Source Type: research

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort
DISCUSSION: The magnitude of the association between PFAS exposure and BP might appear small, statistically non-significant and the possible clinical importance low. However, at a population level this may slightly shift the distribution of BP towards an increased incidence of GH. If BP increases in pregnancy, it may have long-term impact on health not only of the pregnant woman but also of her offspring.PMID:33610053 | DOI:10.1016/j.envint.2021.106442 (Source: Environment International)
Source: Environment International - February 20, 2021 Category: Environmental Health Authors: Anna Birukov Louise Bj ørkholt Andersen Marianne Skovsager Andersen Julie H Nielsen Flemming Nielsen Henriette Boye Kyhl Jan Stener J ørgensen Philippe Grandjean Ralf Dechend Tina Kold Jensen Source Type: research

Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study
Environ Int. 2021 Feb 17;151:106443. doi: 10.1016/j.envint.2021.106443. Online ahead of print.ABSTRACTIMPORTANCE: Exposure to phthalates may affect fetal growth, but previous studies are inconsistent and have not explored the trimester-specific effects of phthalates on repeated measures of fetal growth.OBJECTIVE: To assess the associations of maternal phthalate metabolites urine concentrations with fetal growth measures and birth outcomes and identify potential windows of vulnerability to exposure.DESIGN: Population-based prospective cohort study, the Generation R Study (2002-2006). Data analysis was performed from Novembe...
Source: Environment International - February 20, 2021 Category: Environmental Health Authors: Susana Santos Chalana M Sol Charissa van Zwol-Janssens Elise M Philips Alexandros G Asimakopoulos Maria-Pilar Martinez-Moral Kurunthachalam Kannan Vincent W V Jaddoe Leonardo Trasande Source Type: research

Short-term exposure to ozone, nitrogen dioxide, and sulphur dioxide and emergency department visits and hospital admissions due to asthma: A systematic review and meta-analysis
CONCLUSION: Short-term exposure to daily O3, NO2, and SO2 was associated with an increased risk of asthma exacerbation in terms of asthma-associated ERVs and HAs.PMID:33601224 | DOI:10.1016/j.envint.2021.106435 (Source: Environment International)
Source: Environment International - February 18, 2021 Category: Environmental Health Authors: Xue-Yan Zheng Pablo Orellano Hua-Liang Lin Mei Jiang Wei-Jie Guan Source Type: research

Short-term exposure to sulphur dioxide (SO < sub > 2 < /sub > ) and all-cause and respiratory mortality: A systematic review and meta-analysis
The objective of this study was to evaluate all the available evidence of the effect of short-term exposure to ambient sulphur dioxide (SO2) on all-cause and respiratory mortality.METHODS: Articles reporting observational epidemiological studies were included, comprising time-series and case-crossover designs. A broad search and wide inclusion criteria were considered, encompassing international and regional databases, with no geographical or language restrictions. A random effect meta-analysis was conducted, and pooled relative risk for an increment of 10 µg/m3 in SO2 concentrations were calculated for each outcome....
Source: Environment International - February 18, 2021 Category: Environmental Health Authors: Pablo Orellano Julieta Reynoso Nancy Quaranta Source Type: research

Concentration-dependent health effects of air pollution in controlled human exposures
We examined PM concentration-responses after controlled human air pollution exposures to examine exposure-response markers, assess effect modifiers, and identify potential effect thresholds.METHODS: We reviewed primary research from published controlled human exposure studies where responses were reported at multiple target PM concentrations or summarized per unit change in PM to identify concentration-dependent effects.RESULTS: Of the 191 publications identified through PubMed and supplementary searches, 31 were eligible. Eligible studies collectively represented four pollutant models: concentrated ambient particles, engi...
Source: Environment International - February 17, 2021 Category: Environmental Health Authors: Juma Orach Christopher F Rider Christopher Carlsten Source Type: research

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
DISCUSSION: The magnitude of the association between PFAS exposure and BP might appear small, statistically non-significant and the possible clinical importance low. However, at a population level this may slightly shift the distribution of BP towards an increased incidence of GH. If BP increases in pregnancy, it may have long-term impact on health not only of the pregnant woman but also of her offspring. PMID: 33610053 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - February 17, 2021 Category: Environmental Health Authors: Birukov A, Andersen LB, Andersen MS, Nielsen JH, Nielsen F, Kyhl HB, Jørgensen JS, Grandjean P, Dechend R, Jensen TK Tags: Environ Int Source Type: research

Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study.
Abstract IMPORTANCE: Exposure to phthalates may affect fetal growth, but previous studies are inconsistent and have not explored the trimester-specific effects of phthalates on repeated measures of fetal growth. OBJECTIVE: To assess the associations of maternal phthalate metabolites urine concentrations with fetal growth measures and birth outcomes and identify potential windows of vulnerability to exposure. DESIGN: Population-based prospective cohort study, the Generation R Study (2002-2006). Data analysis was performed from November 2019 to June 2020. SETTING: Rotterdam, the Netherlands. PART...
Source: Environment International - February 17, 2021 Category: Environmental Health Authors: Santos S, Sol CM, van Zwol-Janssens C, Philips EM, Asimakopoulos AG, Martinez-Moral MP, Kannan K, Jaddoe VWV, Trasande L Tags: Environ Int Source Type: research

Short-term exposure to ozone, nitrogen dioxide, and sulphur dioxide and emergency department visits and hospital admissions due to asthma: A systematic review and meta-analysis.
CONCLUSION: Short-term exposure to daily O3, NO2, and SO2 was associated with an increased risk of asthma exacerbation in terms of asthma-associated ERVs and HAs. PMID: 33601224 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - February 15, 2021 Category: Environmental Health Authors: Zheng XY, Orellano P, Lin HL, Jiang M, Guan WJ Tags: Environ Int Source Type: research

Short-term exposure to sulphur dioxide (SO2) and all-cause and respiratory mortality: A systematic review and meta-analysis.
The objective of this study was to evaluate all the available evidence of the effect of short-term exposure to ambient sulphur dioxide (SO2) on all-cause and respiratory mortality. METHODS: Articles reporting observational epidemiological studies were included, comprising time-series and case-crossover designs. A broad search and wide inclusion criteria were considered, encompassing international and regional databases, with no geographical or language restrictions. A random effect meta-analysis was conducted, and pooled relative risk for an increment of 10 µg/m3 in SO2 concentrations were calculated for ea...
Source: Environment International - February 15, 2021 Category: Environmental Health Authors: Orellano P, Reynoso J, Quaranta N Tags: Environ Int Source Type: research

Concentration-dependent health effects of air pollution in controlled human exposures.
We examined PM concentration-responses after controlled human air pollution exposures to examine exposure-response markers, assess effect modifiers, and identify potential effect thresholds. METHODS: We reviewed primary research from published controlled human exposure studies where responses were reported at multiple target PM concentrations or summarized per unit change in PM to identify concentration-dependent effects. RESULTS: Of the 191 publications identified through PubMed and supplementary searches, 31 were eligible. Eligible studies collectively represented four pollutant models: concentrated ambient par...
Source: Environment International - February 14, 2021 Category: Environmental Health Authors: Orach J, Rider CF, Carlsten C Tags: Environ Int Source Type: research

Evidence for selection of multi-resistant E. coli by hospital effluent.
Abstract There is a risk that residues of antibiotics and other antimicrobials in hospital and municipal wastewaters could select for resistant bacteria. Still, direct experimental evidence for selection is lacking. Here, we investigated if effluent from a large Swedish hospital, as well as influent and effluent from the connected municipal wastewater treatment plant (WWTP) select for antibiotic resistant Escherichia coli in three controlled experimental setups. Exposure of sterile-filtered hospital effluent to a planktonic mix of 149 different E. coli wastewater isolates showed a strong selection of multi-resista...
Source: Environment International - February 13, 2021 Category: Environmental Health Authors: Kraupner N, Hutinel M, Schumacher K, Gray DA, Genheden M, Fick J, Flach CF, Larsson DGJ Tags: Environ Int Source Type: research

Spatiotemporal variations in the association between particulate matter and airborne bacteria based on the size-resolved respiratory tract deposition in concentrated layer feeding operations.
Abstract Bacterial loading aggravates the health and environmental hazards of particulate matter (PM), particularly in concentrated animal feeding operations. Understanding the association between PM and airborne bacteria is conducive to accurately assessing occupational exposure, providing fundamental data for exposure mitigation via engineering solutions, and providing information regarding the physical properties influencing the transmission of airborne microorganisms at emission sources. In this work, we conducted a joint study to systematically determine the concentrations and size distributions of PM and air...
Source: Environment International - February 11, 2021 Category: Environmental Health Authors: Li Z, Zheng W, Wang Y, Li B, Wang Y Tags: Environ Int Source Type: research

Total mercury concentration in placental tissue, a good biomarker of prenatal mercury exposure, is associated with risk for neural tube defects in offspring.
Abstract OBJECTIVE: To examine the role of total mercury (T-Hg) in placenta as a biomarker of prenatal mercury (Hg) exposure and determine the association between prenatal Hg exposure and risk for neural tube defects (NTDs) in offspring. METHODS: Total Hg concentrations in placental tissue were detected in 408 NTD cases and 593 healthy controls enrolled in Shanxi province in northern China. Methylmercury (MeHg) and T-Hg were also detected in the umbilical cord of 147 NTD cases and 140 healthy controls. In addition, MeHg and T-Hg were detected in fetal kidney, liver, and brain tissues of 51 NTD cases. Spearman...
Source: Environment International - February 10, 2021 Category: Environmental Health Authors: Tong M, Yu J, Liu M, Li Z, Wang L, Yin C, Ren A, Chen L, Jin L Tags: Environ Int Source Type: research

Showcasing the potential of wastewater-based epidemiology to track pharmaceuticals consumption in cities: Comparison against prescription data collected at fine spatial resolution.
P, Corominas L Abstract While the extent of pharmaceutical consumption within a society/community is of high relevance to its health, economy and general wellbeing, this data is often not readily available. Herein, we strengthen a wastewater-based epidemiology (WBE) approach as a way to track the consumption of pharmaceuticals within the sampled community. This method is less laborious than established questionnaire or databases approaches and allows a higher temporal and spatial resolution. The WBE approach was conducted by sampling influent wastewater from two wastewater treatment plants of different size. A to...
Source: Environment International - February 9, 2021 Category: Environmental Health Authors: Escolà Casas M, Schröter NS, Zammit I, Castaño-Trias M, Rodriguez-Mozaz S, Gago-Ferrero P, Corominas L Tags: Environ Int Source Type: research

Seasonal changes dominate long-term variability of the urban air microbiome across space and time.
In this study, we surveyed the composition, variability and sources of microbes (bacteria and fungi) in the near surface atmosphere of a highly populated area, spanning ~ 4,000 Km2 around the city center of Madrid (Spain), in different seasonal periods along two years. We found a core of abundant bacterial genera robust across space and time, most of soil origin, while fungi were more sensitive to environmental conditions. Microbial communities showed clear seasonal patterns driven by variability of environmental factors, mainly temperature and accumulated rain, while local sources played a minor role. We also id...
Source: Environment International - February 9, 2021 Category: Environmental Health Authors: Núñez A, García AM, Moreno DA, Guantes R Tags: Environ Int Source Type: research