Roseihalotalea indica gen. nov., sp. nov., a halophilic Bacteroidetes from mesopelagic Southwest Indian Ocean with higher carbohydrate metabolic potential
Antonie Van Leeuwenhoek. 2024 Apr 12;117(1):66. doi: 10.1007/s10482-024-01965-x.ABSTRACTThe pink-colored and strictly aerobic bacterium strain, designated as TK19036T, was isolated from mesopelagic layer of the Southwest Indian Ocean. This novel isolate can grow at 10-45 °C (optimum, 30 °C), pH 6.0-8.0 (optimum, pH 7.0), and 2-14% NaCl concentrations (w/v) (optimum, 6%). The predominant respiratory quinone was Menaquinone-7. Major polar lipid profiles contained two aminolipids, aminophospholipid, two glycolipids, phosphatidylethanolamine, and three unknown polar lipids. The preponderant cellular fatty acids were iso-C15:...
Source: Antonie van Leeuwenhoek - April 12, 2024 Category: Microbiology Authors: Beihan Chen Mingzhe Zhang Dan Lin Jianing Ye Kai Tang Source Type: research
Unveiling the complexity of early childhood caries: < em > Candida albicans < /em > and < em > Streptococcus mutans < /em > cooperative strategies in carbohydrate metabolism and virulence
CONCLUSION: The symbiotic relationship between C. albicans and S. mutans, and their interactions through carbohydrate metabolism and environmental acidification, are key factors in the pathogenesis of ECC. A comprehensive understanding of these mechanisms is crucial for developing effective strategies to manage and treat ECC.PMID:38606339 | PMC:PMC11008315 | DOI:10.1080/20002297.2024.2339161 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 12, 2024 Category: Microbiology Authors: Pingping Jin Lu Wang Daozhen Chen Yu Chen Source Type: research
Substituting carbohydrate at lunch for added protein increases fat oxidation during subsequent exercise in healthy males
CONCLUSION: Substituting carbohydrate for protein in a pre-exercise lunch increased fat oxidation, suppressed subjective and hormonal appetite, and reduced post-exercise energy intake.PMID:38609167 | DOI:10.1210/clinem/dgae237 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Tommy Slater William J A Mode Louise C Bonnard Cian Sweeney Mark P Funnell Harry A Smith John Hough Ruth M James Ian Varley Craig Sale James A Betts Lewis J James David J Clayton Source Type: research
Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research
Validating nutrient selection for product-group-specific nutrient indices for use as functional units in life cycle assessment of foods
Br J Nutr. 2024 Apr 12:1-23. doi: 10.1017/S0007114524000709. Online ahead of print.ABSTRACTThe ability to provide adequate nutrition is considered a key factor in evaluating the sustainability of foods and diets. Nutrient indices are used as functional units (FUs) in life cycle assessment of foods to include nutritional performance in the environmental assessment of a product. Several general and food group-specific nutrient indices exist but many lack validation, particularly when used as FU. In addition, the nutrient selection strategies and reference units for nutrient intake can vary considerably among studies. To vali...
Source: The British Journal of Nutrition - April 12, 2024 Category: Nutrition Authors: Anna K årlund Venla Kytt ä Tiina Pellinen Hanna L Tuomisto Anne-Maria Pajari Marjukka Kolehmainen Merja Saarinen Source Type: research
Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells
Gene. 2024 Apr 10:148441. doi: 10.1016/j.gene.2024.148441. Online ahead of print.ABSTRACTType 2 diabetes (T2D) is posing a serious public health concern with a considerable impact on human life and health expenditures worldwide. The disease develops when insulin plasma level is insufficient for coping insulin resistance, caused by the decline of pancreatic β-cell function and mass. In β-cells, the lipotoxicity exerted by saturated free fatty acids in particular palmitate (PA), which is chronically elevated in T2D, plays a major role in β-cell dysfunction and mass. However, there is a lack of human relevant in vitro mode...
Source: Gene - April 12, 2024 Category: Genetics & Stem Cells Authors: Lisa Morisseau Fumiya Tokito Mathilde Lucas St éphane Poulain Soo Hyeon Kim Val érie Plaisance Val érie Pawlowski C écile Legallais Rachid Jellali Yasuyuki Sakai Amar Abderrahmani Eric Leclerc Source Type: research
Roseihalotalea indica gen. nov., sp. nov., a halophilic Bacteroidetes from mesopelagic Southwest Indian Ocean with higher carbohydrate metabolic potential
Antonie Van Leeuwenhoek. 2024 Apr 12;117(1):66. doi: 10.1007/s10482-024-01965-x.ABSTRACTThe pink-colored and strictly aerobic bacterium strain, designated as TK19036T, was isolated from mesopelagic layer of the Southwest Indian Ocean. This novel isolate can grow at 10-45 °C (optimum, 30 °C), pH 6.0-8.0 (optimum, pH 7.0), and 2-14% NaCl concentrations (w/v) (optimum, 6%). The predominant respiratory quinone was Menaquinone-7. Major polar lipid profiles contained two aminolipids, aminophospholipid, two glycolipids, phosphatidylethanolamine, and three unknown polar lipids. The preponderant cellular fatty acids were iso-C15:...
Source: Antonie van Leeuwenhoek - April 12, 2024 Category: Microbiology Authors: Beihan Chen Mingzhe Zhang Dan Lin Jianing Ye Kai Tang Source Type: research
Unveiling the complexity of early childhood caries: < em > Candida albicans < /em > and < em > Streptococcus mutans < /em > cooperative strategies in carbohydrate metabolism and virulence
CONCLUSION: The symbiotic relationship between C. albicans and S. mutans, and their interactions through carbohydrate metabolism and environmental acidification, are key factors in the pathogenesis of ECC. A comprehensive understanding of these mechanisms is crucial for developing effective strategies to manage and treat ECC.PMID:38606339 | PMC:PMC11008315 | DOI:10.1080/20002297.2024.2339161 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 12, 2024 Category: Microbiology Authors: Pingping Jin Lu Wang Daozhen Chen Yu Chen Source Type: research
Substituting carbohydrate at lunch for added protein increases fat oxidation during subsequent exercise in healthy males
CONCLUSION: Substituting carbohydrate for protein in a pre-exercise lunch increased fat oxidation, suppressed subjective and hormonal appetite, and reduced post-exercise energy intake.PMID:38609167 | DOI:10.1210/clinem/dgae237 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Tommy Slater William J A Mode Louise C Bonnard Cian Sweeney Mark P Funnell Harry A Smith John Hough Ruth M James Ian Varley Craig Sale James A Betts Lewis J James David J Clayton Source Type: research
Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research
Validating nutrient selection for product-group-specific nutrient indices for use as functional units in life cycle assessment of foods
Br J Nutr. 2024 Apr 12:1-23. doi: 10.1017/S0007114524000709. Online ahead of print.ABSTRACTThe ability to provide adequate nutrition is considered a key factor in evaluating the sustainability of foods and diets. Nutrient indices are used as functional units (FUs) in life cycle assessment of foods to include nutritional performance in the environmental assessment of a product. Several general and food group-specific nutrient indices exist but many lack validation, particularly when used as FU. In addition, the nutrient selection strategies and reference units for nutrient intake can vary considerably among studies. To vali...
Source: The British Journal of Nutrition - April 12, 2024 Category: Nutrition Authors: Anna K årlund Venla Kytt ä Tiina Pellinen Hanna L Tuomisto Anne-Maria Pajari Marjukka Kolehmainen Merja Saarinen Source Type: research
Unveiling the complexity of early childhood caries: < em > Candida albicans < /em > and < em > Streptococcus mutans < /em > cooperative strategies in carbohydrate metabolism and virulence
CONCLUSION: The symbiotic relationship between C. albicans and S. mutans, and their interactions through carbohydrate metabolism and environmental acidification, are key factors in the pathogenesis of ECC. A comprehensive understanding of these mechanisms is crucial for developing effective strategies to manage and treat ECC.PMID:38606339 | PMC:PMC11008315 | DOI:10.1080/20002297.2024.2339161 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 12, 2024 Category: Microbiology Authors: Pingping Jin Lu Wang Daozhen Chen Yu Chen Source Type: research
Substituting carbohydrate at lunch for added protein increases fat oxidation during subsequent exercise in healthy males
CONCLUSION: Substituting carbohydrate for protein in a pre-exercise lunch increased fat oxidation, suppressed subjective and hormonal appetite, and reduced post-exercise energy intake.PMID:38609167 | DOI:10.1210/clinem/dgae237 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Tommy Slater William J A Mode Louise C Bonnard Cian Sweeney Mark P Funnell Harry A Smith John Hough Ruth M James Ian Varley Craig Sale James A Betts Lewis J James David J Clayton Source Type: research
Observations of the effectiveness, dosage, and prognosis of intensity-modulated radiation therapy under ultrasonic guidance for cervical cancer patients
CONCLUSION: VMAT guided by ultrasound for patients with cervical cancer demonstrates promising short- and long-term treatment outcomes. It also leads to improvements in serum CEA, SCC-Ag, and CA724 levels, as well as reductions in the average radiation dosages to the radiotherapy target area, rectum, and bladder. This approach warrants attention from clinicians in clinical practice.PMID:38607778 | DOI:10.3233/THC-231977 (Source: Technology and Health Care)
Source: Technology and Health Care - April 12, 2024 Category: Medical Devices Authors: Chenxi Li Jian Li Yao Lu Jiahui Hou Zhaoyu Zhi Baocun Zhao Xiumei Zhang Source Type: research
Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells
Gene. 2024 Apr 10;917:148441. doi: 10.1016/j.gene.2024.148441. Online ahead of print.ABSTRACTType 2 diabetes (T2D) is posing a serious public health concern with a considerable impact on human life and health expenditures worldwide. The disease develops when insulin plasma level is insufficient for coping insulin resistance, caused by the decline of pancreatic β-cell function and mass. In β-cells, the lipotoxicity exerted by saturated free fatty acids in particular palmitate (PA), which is chronically elevated in T2D, plays a major role in β-cell dysfunction and mass. However, there is a lack of human relevant in vitro ...
Source: Gene - April 12, 2024 Category: Genetics & Stem Cells Authors: Lisa Morisseau Fumiya Tokito Mathilde Lucas St éphane Poulain Soo Hyeon Kim Val érie Plaisance Val érie Pawlowski C écile Legallais Rachid Jellali Yasuyuki Sakai Amar Abderrahmani Eric Leclerc Source Type: research
