Carbohydrates Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Carbohydrate binding modules: Compact yet potent accessories in the specific substrate binding and performance evolution of carbohydrate-active enzymes
Biotechnol Adv. 2024 Apr 25:108365. doi: 10.1016/j.biotechadv.2024.108365. Online ahead of print.ABSTRACTCarbohydrate binding modules (CBMs) are independent non-catalytic domains widely found in carbohydrate-active enzymes (CAZymes), and they play an essential role in the substrate binding process of CAZymes by guiding the appended catalytic modules to the target substrates. Owing to their precise recognition and selective affinity for different substrates, CBMs have received increasing research attention over the past few decades. To date, CBMs from different origins have formed a large number of families that show a vari...
Source: Biotechnology Advances - April 27, 2024 Category: Biotechnology Authors: Yuxian You Haocun Kong Caiming Li Zhengbiao Gu Xiaofeng Ban Zhaofeng Li Source Type: research

Anti-Atherosclerotic Properties of Aronia melanocarpa Extracts Influenced by Their Chemical Composition Associated with the Ripening Stage of the Berries
In this study, the anti-atherosclerotic effect of Aronia extracts was assessed. The impact on the level of adhesion molecules and the inflammatory response of human umbilical vein endothelial cells (HUVECs) was shown in relation to the chemical composition and the stage of ripening of the fruits. Samples were collected between May (green, unripe) and October (red, overripe) on two farms in Poland, which differed in climate. The content of chlorogenic acids, anthocyanins, and carbohydrates in the extracts was determined using HPLC-DAD/RI. The surface expression of ICAM-1 and VCAM-1 in HUVECs was determined by flow cytometry...
Source: Atherosclerosis - April 27, 2024 Category: Cardiology Authors: Agnieszka Zieli ńska Dorota Bryk Katarzyna Paradowska Pawe ł Siudem Iwona Wawer Ma łgorzata Wrzosek Source Type: research

Diabetic Cardiomyopathy-From Basics through Diagnosis to Treatment
Biomedicines. 2024 Mar 29;12(4):765. doi: 10.3390/biomedicines12040765.ABSTRACTDiabetic cardiomyopathy (DCM) is the development of myocardial dysfunction in patients with diabetes despite the absence of comorbidities such as hypertension, atherosclerosis or valvular defect. The cardiovascular complications of poorly controlled diabetes are very well illustrated by the U.K. Prospective Diabetes Study (UKPDS), which showed a clear association between increasing levels of glycated hemoglobin and the development of heart failure (HF). The incidence of HF in patients with diabetes is projected to increase significantly, which i...
Source: Atherosclerosis - April 27, 2024 Category: Cardiology Authors: Ewa Radzioch Bart łomiej Dąbek Marta Balcerczyk-Lis Weronika Fr ąk Piotr Fularski Ewelina M łynarska Jacek Rysz Beata Franczyk Source Type: research

Trends in preoperative carbohydrate load practice: A systematic review
CONCLUSION: Variation in PCL practices prevent meaningful data pooling and outcome analysis, highlighting the need for standardized PCL prescription. Efforts dedicated to the establishment of a gold standard PCL prescription are necessary so that studies can be pooled and analyzed with respect to meaningful clinical end points that impact surgical outcomes and patient satisfaction.PMID:38676554 | DOI:10.1002/jpen.2633 (Source: JPEN Journal Of Parenteral And Enteral Nutrition)
Source: JPEN Journal Of Parenteral And Enteral Nutrition - April 27, 2024 Category: Nutrition Authors: Robert J Canelli Joseph Louca Rafael M Gonzalez Luis F Rendon Ciana R Hartman Federico Bilotta Source Type: research

An investigation on antimicrobial and anticancer competence of macro red algae under in-vitro condition
Environ Res. 2024 Apr 25:119026. doi: 10.1016/j.envres.2024.119026. Online ahead of print.ABSTRACTThe purpose of this study was to look into the proximate parameters (moisture, ash, total fat, protein, and total carbohydrate) , mineral composition (Fe, Cu, Mg, and Zn ), antimicrobial as well as cytotoxic (anticancer) properties of extracts from the marine red macro algae Gracilaria corticata, Chondrus ocellatus, and Posphyra perforata against a few prevalent microbial pathogens (Salmonella typhi, Streptococcus pneumoniae, Corynebacterium diphtheriae, Clostridium tetani, and Treponema pallidum as well as fungal pathogens su...
Source: Environmental Research - April 27, 2024 Category: Environmental Health Authors: Thi-Van Hoang Saleh Alfarraj Sulaiman Ali Alharbi Source Type: research

Ultrasensitive NIR fluorometric assay for inorganic pyrophosphatase detection via Cu 2+ -PPi interaction using bimetallic Au-Ag nanoclusters
Anal Chim Acta. 2024 May 29;1305:342584. doi: 10.1016/j.aca.2024.342584. Epub 2024 Apr 10.ABSTRACTBACKGROUND: Inorganic pyrophosphatase (PPase) is key enzyme playing a key role in biochemical transformations such as biosynthesis of DNA and RNA, bone formation, metabolic pathways associated with lipid, carbohydrate and phosphorous. It has been reported that lung adenocarcinomas, colorectal cancer, and hyperthyroidism disorders can result from abnormal level of PPase. Therefore, it is of notable significance to develop simple and effective real time assay for PPase enzyme activity monitoring for screening of many metabolic p...
Source: Analytica Chimica Acta - April 27, 2024 Category: Chemistry Authors: Deepika Sharma Nishima Wangoo Rohit K Sharma Source Type: research

Techno-economic analysis of biomass value-added processing informed by pilot scale de-ashing of paper sludge feedstock
Bioresour Technol. 2024 Apr 25:130744. doi: 10.1016/j.biortech.2024.130744. Online ahead of print.ABSTRACTPaper sludge biomass represents an underutilized feedstock rich in pulped and processed cellulose which is currently a waste stream with significant disposal cost to industry for landfilling services. Effective fractionation of the cellulose from paper sludge presents an opportunity to yield cellulose as feedstock for value-added processes. A novel approach to cellulose fractionation is the sidehill screening system, herein studied at the pilot-plant scale. Composition analysis determined ash removal and carbohydrate r...
Source: Bioresource Technology - April 27, 2024 Category: Biotechnology Authors: Phoenix Tiller Hyeonji Park David Cruz Rios Edgar Carrejo David K Johnson Ashutosh Mittal Richard Venditti Sunkyu Park Source Type: research

Molecules, Vol. 29, Pages 2017: Borane & ndash;Trimethylamine Complex: A Versatile Reagent in Organic Synthesis
Molecules, Vol. 29, Pages 2017: Borane–Trimethylamine Complex: A Versatile Reagent in Organic Synthesis Molecules doi: 10.3390/molecules29092017 Authors: Dario Perdicchia Borane&ndash;trimethylamine complex (Me3N&middot;BH3; BTM) is the most stable of the amine&ndash;borane complexes that are commercially available, and it is cost-effective. It is a valuable reagent in organic chemistry with applications in the reduction of carbonyl groups and carbon&ndash;nitrogen double bond reduction, with considerable examples in the reduction of oximes, hydrazones and azines. The trans...
Source: Molecules - April 27, 2024 Category: Chemistry Authors: Dario Perdicchia Tags: Review Source Type: research

Ketogenic Diets Hold Therapeutic Potential Against Periodontal Inflammation
AbstractPurpose of ReviewPeriodontitis, one of the most prevalent diseases in the world, is caused by the accumulation of dysbiotic microbial biofilm on the teeth leading to chronic inflammation of the tissues surrounding the teeth. Type 2 diabetes mellitus (T2DM), obesity, chronic stress, and smoking are some of the risk factors for the disease. A high-carbohydrate diet also increases the risk of periodontal inflammation. Modifying diet and nutrition could serve as a preventive and therapeutic tool to target multiple risk factors simultaneously.Recent FindingsEmerging evidence shows that the ketogenic diet induces hormeti...
Source: Current Oral Health Reports - April 27, 2024 Category: Dentistry Source Type: research

Altered mucosal bacteria and metabolomics in patients with Peutz –Jeghers syndrome
ConclusionThis is the first report on the mucosa-associated microbiota and metabolite profile of subjects with PJS, which may be meaningful to provide a structural basis for further research on intestinal microecology in PJS. (Source: Gut Pathogens)
Source: Gut Pathogens - April 27, 2024 Category: Microbiology Source Type: research

Carbon dioxide valorization into resveratrol via lithoautotrophic fermentation using engineered Cupriavidus necator H16
Industrial biomanufacturing of value-added products using CO2 as a carbon source is considered more sustainable, cost-effective and resource-efficient than using common carbohydrate feedstocks. Cupriavidus necato... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - April 27, 2024 Category: Microbiology Authors: Yongjae Jang, Yeon Ji Lee, Gyeongtaek Gong, Sun-Mi Lee, Youngsoon Um, Kyoung Heon Kim and Ja Kyong Ko Tags: Research Source Type: research

Reading and Writing the Human Glycocode
Annu Rev Biochem. 2024 Apr 26. doi: 10.1146/annurev-biochem-030122-044347. Online ahead of print.ABSTRACTThe complex carbohydrate structures decorating human proteins and lipids, also called glycans, are abundantly present at cell surfaces and in the secretome. Glycosylation is vital for biological processes including cell-cell recognition, immune responses, and signaling pathways. Therefore, the structural and functional characterization of the human glycome is gaining more and more interest in basic biochemistry research and in the context of developing new therapies, diagnostic tools, and biotechnology applications. For...
Source: Annual Review of Biochemistry - April 26, 2024 Category: Biochemistry Authors: Noortje de Haan Mathias I Nielsen Hans H Wandall Source Type: research

Synthesis of C3- epi -virenose and anomerically activated derivatives
Tetrahedron Lett. 2024 Apr;140:155041. doi: 10.1016/j.tetlet.2024.155041.ABSTRACTA 9-step synthetic route to a protected form of the C3-epimer of virenose from D-fucose is described. C3-epi-virenose is the carbohydrate unit of the bioactive polyketide elsamicin B and part of the carbohydrate unit of elsamicin A. The developed route enabled preparation of anomerically activated forms of this unique C6-deoxy sugar, including derivatives with 1-acetyl, 1-acetylthio, 1-trichloroacetimidate, 1-bromo, and 1-fluoro substituents.PMID:38665383 | PMC:PMC7615872 | DOI:10.1016/j.tetlet.2024.155041 (Source: Tetrahedron Letters)
Source: Tetrahedron Letters - April 26, 2024 Category: Chemistry Authors: Liesa R öder Sofia Torres Venegas Klaus Wurst Thomas Magauer Source Type: research