Identifying risk factors for hypoxemia during emergence from anesthesia in patients undergoing robot-assisted laparoscopic radical prostatectomy
This study aims to identify risk factors related to hypoxemia during the emergence from anesthesia in patients undergoing RALP. A cohort of 316 patients undergoing RALP was divided into two groups: the hypoxemia group (N = 134) and the non-hypoxemia group (N = 182), based on their postoperative oxygen fraction. Comprehensive data were collected from the hospital information system, including preoperative baseline parameters, intraoperative data, and postoperative recovery profiles. Risk factors were examine d using multiple logistic regression analysis. The study showed that 38.9% of patients had low preoperative ...
Source: Journal of Robotic Surgery - May 7, 2024 Category: Surgery Source Type: research
Robotic ambulatory colorectal resections: a systematic review
AbstractColorectal surgery has progressed greatly via minimally invasive techniques, laparoscopic and robotic. With the advent of ERAS protocols, patient recovery times have greatly shortened, allowing for same day discharges (SDD). Although SDD have been explored through laparoscopic colectomy reviews, no reviews surrounding robotic ambulatory colorectal resections (RACrR) exist to date. A systematic search was carried out across three databases and internet searches. Data were selected and extracted by two independent reviewers. Inclusion criteria included robotic colorectal resections with a length of hospital stay of l...
Source: Journal of Robotic Surgery - May 7, 2024 Category: Surgery Source Type: research
Laparoscopic Sleeve Gastrectomy as a First Step Procedure for Oncologic Purposes: An Indication Beyond the Updated Guidelines
ConclusionLSG can be proposed as bridging procedure before oncological surgery in meticulously selected patients. Achieved weight loss can render subsequent oncological procedures easier and safer.Graphical Abstract (Source: Obesity Surgery)
Source: Obesity Surgery - May 7, 2024 Category: Surgery Source Type: research
Effect of MELD-Na score on overall survival of periampullary cancer
This study aimed to investigate the effect of MELD-Na scores on OS in patients undergoing pancreaticoduodenectomy due to periampullary cancer. Patients who underwent pancreaticoduodenectomy due to periampullary cancer between January 2010 and January 2021 were included in the study. After applying the exclusion criteria, 80 of the 124 patients were included in the study. The demographic, laboratory, and pathologic data of the patients were analyzed retrospectively. Univariate analysis showed that MELD-Na score at admission, age-adjusted Charlson Comorbidity Index, adjuvant treatment, portal vein resection, lymphovascular i...
Source: Updates in Surgery - May 7, 2024 Category: Surgery Source Type: research
Breast cancer incidence, stage distribution, and treatment shifts during the 2020 COVID-19 pandemic: a nationwide population-level study
ConclusionsBC incidence decline in 2020 in Belgium was largely restricted to very early-stage BC and patients aged 50 and over. Delayed diagnosis did not result in an overall progression to higher stage at diagnosis in 2020. Observed treatment adaptations in Belgium were successful in prioritizing patients for surgery while preventing tumor progression in those with surgical delay. Continuation of monitoring BC incidence and stage in the future is crucial. (Source: Archives of Public Health)
Source: Archives of Public Health - May 7, 2024 Category: International Medicine & Public Health Source Type: research
A novel artificial intelligence-based endoscopic ultrasonography diagnostic system for diagnosing the invasion depth of early gastric cancer
ConclusionsOur AI model demonstrated a diagnostic performance equivalent to that of experts. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - May 7, 2024 Category: Gastroenterology Source Type: research
Active surveillance of nodal metastasis in differentiated thyroid carcinoma: a systematic review and meta-analysis
ConclusionsAS seems to be a suitable strategy for selected DTC patients with small nodal disease, avoiding or postponing surgical reintervention.Prospero registrationCRD42023438293. (Source: Endocrine)
Source: Endocrine - May 7, 2024 Category: Endocrinology Source Type: research
Epi-revolution in rheumatology: the potential of histone deacetylase inhibitors for targeted rheumatoid arthritis intervention
AbstractAutoimmune diseases hold significant importance in the realm of medical research, prompting a thorough exploration of potential therapeutic interventions. One crucial aspect of this exploration involves understanding the intricate processes of histone acetylation and deacetylation. Histone acetylation, facilitated by histone acetyl transferases (HATs), is instrumental in rendering DNA transcriptionally active. Conversely, histone deacetylases (HDACs) are responsible for the removal of acetyl groups, influencing gene expression regulation. The upregulation of HDACs, observed in various cancers, has steered attention...
Source: Inflammopharmacology - May 7, 2024 Category: Drugs & Pharmacology Source Type: research
Acupuncture for the treatment of the pain-fatigue-sleep disturbance-numbness/tingling symptom cluster in breast cancer survivors: a feasibility trial
ConclusionThis study demonstrated that acupuncture was safe and feasible, justifying a powered randomized control trial. Preliminary findings suggest beneficial effects of acupuncture for the management of the pain-fatigue-sleep disturbance-numbness/tingling symptom cluster for women with breast cancer. TCM syndromes identified in this trial may be used to guide acupuncture treatment protocols.Clinical trial registration: This trial was registered with the Australian New Zealand Clinical Trials Registry (ACTRN12622000590763) on 21 April 2022. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - May 7, 2024 Category: Cancer & Oncology Source Type: research
Symptom cluster among cancer survivors from a nationally representative survey: a network analysis
ConclusionsFatigue would be a potential target for alleviating other symptoms through a negative feedback loop of other related symptoms of cancer survivors. In particular, cancer survivors with other chronic diseases should be the focus of attention and strengthen targeted intervention. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - May 7, 2024 Category: Cancer & Oncology Source Type: research
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21
Single nuclear polymorphisms (SNPs) have been published to be correlated with multiple diseases. Transcription Factor 21 (TCF21) is a critical transcription factor involved in various types of cancers. However... (Source: Cancer Cell International)
Source: Cancer Cell International - May 7, 2024 Category: Cancer & Oncology Authors: Xinyi Zhou, Kuan Shen, Shuqing Cao, Pengyu Li, Jian Xiao, Jiacheng Dong, Quan Cheng, Li Hu, Zekuan Xu and Li Yang Tags: Research Source Type: research
New insights into targeted therapy of glioblastoma using smart nanoparticles
In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic appr... (Source: Cancer Cell International)
Source: Cancer Cell International - May 7, 2024 Category: Cancer & Oncology Authors: Habib Ghaznavi, Reza Afzalipour, Samideh Khoei, Saman Sargazi, Sakine Shirvalilou and Roghayeh Sheervalilou Tags: Review Source Type: research
Prognostic significance of preoperative lymphocytes, albumin, and neutrophils (LANR) index in resectable pancreatic ductal adenocarcinoma
The index composed of preoperative lymphocytes, albumin, and neutrophils (LANR), a new composite score based on inflammatory response and nutritional status, has been reported to be associated with the prognos... (Source: BMC Cancer)
Source: BMC Cancer - May 7, 2024 Category: Cancer & Oncology Authors: Jiaru Zhuang, Shan Wang, Yuan Wang, Yibo Wu and Renjing Hu Tags: Research Source Type: research
Immune checkpoint inhibitor (ICI)-based treatment beyond progression with prior immunotherapy in patients with driver-gene negative advanced non-small cell lung cancer
No definite conclusion has yet to be reached for immunotherapy beyond progression(IBP) of first-line immunotherapy as the second-line treatment for advanced NSCLC patients with negative driver genes. Therefore... (Source: BMC Cancer)
Source: BMC Cancer - May 7, 2024 Category: Cancer & Oncology Authors: Min Wang, Xuquan Jing, Feihu Chen, Shuangqing Lu and Yulan Sun Tags: Research Source Type: research
Comprehensive analysis of T-cell regulatory factors and tumor immune microenvironment in stomach adenocarcinoma
Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognos... (Source: BMC Cancer)
Source: BMC Cancer - May 7, 2024 Category: Cancer & Oncology Authors: Shuchang Wang, Weifeng Zhang, Xinrui Wu, Zhu Zhu, Yuanbiao Chen, Wangrui Liu, Junnfei Xu, Li Chen and Chun Zhuang Tags: Research Source Type: research
