Coping experiences of women in the different phases of breast cancer
ConclusionsCoping with breast cancer evolves according to the meaning that the disease receives in each phase. In addition, the analysis by discursive profile shows how the social support context is also related to the coping strategies in each phase. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Prevalence and risk factors of preoperative frailty in Chinese elderly inpatients with gastric and colorectal cancer undergoing surgery: a single-center cross-sectional study using the Groningen Frailty Indicator
This study aimed at investigating the prevalence of frailty and its risk factors in elderly inpatients with gastric and colorectal cancer.MethodsThis cross-sectional study was conducted at a tertiary hospital in China from Mar. 2020 to Nov. 2020. The study enrolled 265 eligible inpatients aged 60 and older with gastric and colorectal cancer who underwent surgery. Demographic and clinical characteristics, biochemical laboratory parameters, and anthropometric data were collected from all patients. The Groningen Frailty Indicator was applied to assess the frailty status of patients. A multivariate logistic regression model an...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Exploring the barriers related to the healthcare system in implementing quality intravenous chemotherapy: a qualitative study
ConclusionThe identification and removal of the barriers related to HCPs and HCSM in  routine care are crucial. Education of and communication with cancer patients and their family caregivers are two important pillars in the quality of intravenous chemotherapy (IV CT) and this education and communication should be based on individualized care and tailored to the unique needs of eac h patient. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Palliative home-based care to pediatric cancer patients: characteristics and healthcare delivered
ConclusionsHome assistance was provided in a high number of patients, with a large proportion needing one or no hospital admissions and 70.1% of them dying at home. Further studies characterizing these patients and the factors which promote early access to palliative care are needed. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Suicidal ideation, distress, and related factors in a population of cancer patients treated in a general acute hospital
We examined the prevalence of SI in cancer patients, investigated the relation between SI and distress, and tried to identify additional associated factors.MethodsA cross-sectional study with patients treated for cancer in a primary care hospital was conducted. Psychosocial distress and SI in 226 patients was assessed. An expert rating scale (PO-Bado-SF) and a self-assessment instrument (QSC-R23) were used to measure distress. SI was assessed with item 9 of the PHQ-9. Data was descriptively analyzed, and correlations and group comparisons between clinically distressed and non-distressed patients were calculated.ResultsSI w...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Sleep problems and their interaction with physical activity and fatigue in hematological cancer patients during onset of high dose chemotherapy
ConclusionsThis study highlights the combined action of sleep problems and physical activity on fatigue during the onset of induction chemotherapy. These two parameters could represent meaningful intervention targets to improve a patient ’s status during chemotherapy.Trial registrationThe study was registered on the WHO trial register (DRKS00007824). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Sleep disturbance in primary brain tumor: prevalence, risk factors, and patient preferences
ConclusionsFindings indicate a high prevalence of sleep disturbance in PBT patients, highlighting the need for increased screening, monitoring, and treatment in our neuro-oncology clinic. Future research would benefit from assessing the efficacy of behavioral treatments for sleep disturbance in this population. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Pain knowledge of patients and family caregivers as predictors of pain management outcomes in cancer patients: a multicenter study in China
ConclusionPain knowledge of patients and family caregivers were important indicators of pain management outcomes, indicating tailored cancer pain education program should be developed. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Consensus-based recommendations for psychosocial support measures for parents and adult children at the end of life: results of a Delphi study in Germany
ConclusionThe Delphi-consented recommendations for parents and adult children at the end of life provide the first guidance for hands-on dyadic psychosocial support measures for parent –adult child relationships, specifically. The next step could involve the structured implementation of the recommendations, accompanied by scientific research.This study was registered on October 27, 2017, with the German Clinical Trials Register (DRKS00013206). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Correlates of financial toxicity in adult cancer patients and their informal caregivers
AbstractBackgroundFinancial toxicity is commonly reported by cancer patients, but few studies have assessed caregiver perceptions. We aimed to validate the modified Comprehensive Score for Financial Toxicity (COST) in cancer caregivers, identify factors associated with financial toxicity in both patients and caregivers, and assess the association of caregiver financial toxicity with patient and caregiver outcomes.MethodsUsing a convenience sampling method, 100 dyads of adult cancer patients and a primary caregiver visiting outpatient oncology clinics (Jan –Sep 2019) were recruited. We assessed the internal consistenc...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Effects of a miconazole oral patch on preventing development of oral candidiasis in patients with head and neck cancer undergoing radiotherapy: results of a preliminary study quantifying the prevalence of Candida albicans in saliva
ConclusionThis study suggested that prophylactic use of a miconazole oral patch was effective in suppressing the growth ofC. albicans count in saliva during RT for head and neck cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

An educational bereavement program to decrease clinical staff ’s barriers and improve self-efficacy of providing bereavement care
This study aims to investigate the effects of an educational bereavement program on emotional and cognitive barriers, self-efficacy, and professional quality of life among clinicians in hospice care.MethodsA pretest –posttest design was implemented. A total of 194 clinicians with working experience in hospice care were recruited. The participants underwent a 12-h workshop. The content included lectures, role-play, and group discussion. Emotional and cognitive barriers, self-efficacy, and professional quality of life were measured before and after the program and at 3-month follow-up.ResultsAfter the educational progr...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Physical activity and sedentary time: associations with fatigue, pain, and depressive symptoms over 4  years post-treatment among breast cancer survivors
This study prospectively examined the lifestyle behaviors of moderate-to-vigorous PA (MVPA) and ST as predictors of depressive symptoms, pain, and fatigue in breast cancer survivors using longitudinal data from early post-treatment to 4-year survivorship.MethodsBreast cancer survivors (n = 199, mean(SD) age = 55.0(11.0) years) self-reported depressive symptoms, pain, and fatigue, and wore an accelerometer to measure MVPA and ST every 3 months during the first year (times 1 to 5) and 2 and 4 years (times 6 and 8) post-cancer treatment. Linear mixed models were adjusted for personal (e.g...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Association between respiratory and heart rate fluctuations and death occurrence in dying cancer patients: continuous measurement with a non-wearable monitor
ConclusionThe maximum respiratory rate and mean heart rate measured every minute using a monitor can warn family caregivers and care staff, with the support of palliative care professionals, of imminent death among dying patients at home or other facilities. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Risk factors for dysgeusia during chemotherapy for solid tumors: a retrospective cross-sectional study
This study retrospectively analyzed the risk factors for transchemotherapy dysgeusia.MethodsBefore each chemotherapy cycle, patients were routinely evaluated for the presence/severity of dysgeusia based on the Common Terminology Criteria for Adverse Events (CTCAE) v5.0 scale for adverse effects and graded as follows: 0, no change in taste; 1, altered taste with no impact on eating habits; or 2, altered taste with an impact on eating habits. Information from 2 years of evaluations was collected and patient medical records were reviewed to obtain data on chemotherapy cycle, sex, age, body mass index, body surface area, prima...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Managing sexual dysfunction for women with breast cancer: the perspective of healthcare providers in North East Malaysia
ConclusionTherefore, interventions to empower the knowledge, break the socio-cultural barriers, and improve the clinic settings are crucial for HCPs in managing FSD confidently. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Letter to the editor referencing “Body composition changes in patients with head and neck cancer under active treatment: a scoping review”
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Timing of blood sampling to alleviate chemotherapy contraindications
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Usefulness of the FilmArray Meningitis/Encephalitis Panel in diagnosis of central nervous system infection after allogeneic hematopoietic stem cell transplantation
ConclusionsOur results suggest that the FAMEP can be a useful sensitive assay in the screening and diagnosis of CNS viral infections after allogeneic HSCT. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Culture matters: adapting supportive programs for cancer patients in low- and middle-income countries
AbstractThe global burden of cancer falls heavily on low- and middle-income countries (LMICs), where there are critical gaps in the provision of supportive care services, which leaves many cancer patients in these settings feeling overwhelmed and unable to manage the psychological effects associated with a cancer diagnosis and the ensuing treatment. In addressing these gaps, we adapted a widely replicated cancer peer mentoring model in the USA to the Viet Nam context. Using the Cultural Adaptation Framework, we examined cultural characteristics affecting three key domains —cognitive information processing, affective-...
Source: Supportive Care in Cancer - December 1, 2021 Category: Cancer & Oncology Source Type: research

Association of co-morbidities with financial hardship in survivors of adult cancer
ConclusionsImpact of co-morbidities on OOP and financial worry burden was greatest in survivors of low-income families and working-age, respectively. Health insurance and a usual source of care did not relieve the impact of co-morbidities on financial hardship.ImplicationsEffective strategies are warranted to mitigate financial hardship for survivors. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Isolation experienced by women with gestational cancer: could peer support and tailored information be the answer?
AbstractWomen diagnosed with cancer during pregnancy (gestational cancer) are a small but vulnerable population, with experts suggesting they require greater psycho-social support than either other women with cancer or other pregnant women. However, information on their psychological needs remains sparse. This commentary describes our work exploring the psychological needs of women diagnosed with gestational cancer, areas of unmet need we identified, and our recommendations for future programs and research. We conducted in-depth, semi-structured interviews with 23 Australian women diagnosed with gestational cancer in the p...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Clinical utility of a prediction tool to differentiate between breast cancer patients at high or low risk of chemotherapy-induced nausea and vomiting
ConclusionThe PRM was able to identify patients at greater risk of significant nausea but not the other CINV endpoints. As nausea remains a pertinent issue for patients with BC, the PRM could be used to identify these patients a priori for innovative treatment strategies. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Anxiety profiles are associated with stress, resilience and symptom severity in outpatients receiving chemotherapy
ConclusionOur findings suggest that a substantial number of oncology patients may warrant referral to psychological services. Clinicians need to perform systematic assessments of anxiety, stress, and common symptoms and initiate appropriate interventions to enhance resilience and coping. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Recommendations for supportive care and best supportive care in NCCN clinical practice guidelines for treatment of cancer: Differences between solid tumor and hematologic malignancy guidelines
We examined the usage of “supportive care” and “best supportive care” in NCCN guidelines and compared between solid tumor and hematologic malignancy guidelines.MethodsWe reviewed all updated NCCN Guidelines for Treatment of Cancer in October 2019. We documented the frequency of occurrence, definition, and timing of introduction of each term. We compared between solid tumor and hematologic malignancy guidelines.ResultsWe identified a total of 37 solid tumor and 16 hematologic guidelines. Thirty-seven (70%) guidelines mentioned “supportive care” and 36 (68%) mentioned “best supportiv...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Designing a need-based program for relieving psychological distress of family caregivers of leukemia patients: a randomized controlled trial
AbstractPurposeThe family of leukemia patients, due to their caring role, often feels psychological distress. A practical need-based program carefully considers the set of requirements of nursing service recipients. This paper illustrates the efficacy of a designed family-need-based program on relieving stress, anxiety, and depression of family caregivers of leukemia patients.MethodsIn this controlled trial, sixty-four family caregivers of leukemia patients referring to a medical center in Iran were recruited by convenience sampling and randomly divided into study and control groups. The study group attended a designed nee...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Medical management of malignant bowel obstruction in patients with advanced cancer: 2021 MASCC guideline update
ConclusionThe panel recommends octreotide in non-operable MBO. Randomized trials are needed to clarify ranitidine and antiemetic choices. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Antimicrobial prophylaxis and post-chemotherapy neutropenic fever in patients with leukemia: comparisons of C-reactive protein, procalcitonin and immediate fever outcome measures between those with and without prophylaxis, and the implications for practice
ConclusionThe benefits of using antimicrobial prophylaxis were less supported. Enhancing diagnostic laboratory and medical complication surveillance and periodic evaluation of institutional data during post-chemotherapy neutropenia and NF in relation to antimicrobial prophylaxis is promising in providing insights to redefine the risk –benefit accounts of using prophylaxis. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Psychological distress and lower health-related quality of life are associated with need for dietary support among colorectal cancer survivors with overweight or obesity
ConclusionsResults suggest that psychological distress and lower HRQoL should be taken into account while promoting a healthy diet in overweight or obese CRC survivors since these factors may hinder adherence to a healthy diet. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Fatigue and functional outcomes in cancer rehabilitation
ConclusionThis study contributes to existing literature in that it found patients who received inpatient rehabilitation services demonstrate significant improvement in their functional status despite reporting CRF upon admission to a long-term acute care hospital oncology unit. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Survey of practices for the clinical management of febrile neutropenia in children in hematology-oncology units in Latin America
AbstractThe management of febrile neutropenia (FN) in pediatrics is evolving. Our objective was to describe current practices for the care of patients with FN in pediatric oncology centers in Latin America and identify areas for practice improvement. We used an online survey to enroll eligible healthcare providers who treat children with cancer in Latin America. The survey addressed respondents ’ characteristics, the environment of care, and FN care practices, including risk assessment, criteria for hospitalization, initial management of FN, evaluation, antibiotic administration, and discharge. From 220 surveys sent,...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

A randomized trial of medical cannabis in patients with stage IV cancers to assess feasibility, dose requirements, impact on pain and opioid use, safety, and overall patient satisfaction
ConclusionConducting RCTs using a state cannabis program is feasible. The addition of MC to standard oncology care was well-tolerated and may lead to improved pain control and lower opioid requirements. Conducting larger RCTs with MC in state-sponsored programs may guide oncology providers on how to safely and effectively incorporate MC for interested patients. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Effects of the teach-back method among cancer patients: a systematic review of the literature
ConclusionThis study found that teach-back interventions have positive health outcomes including happiness, uncertainty, self-efficacy, self-management behavior, symptom experience, distress, anxiety, and health literacy among cancer patients. However, it found no effects with regard to drug administration, functional measurements, or satisfaction. Future research should continuously examine the teach-back approach and assess its positive health outcomes for cancer patients. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

A pre-post evaluation of oncology healthcare providers ’ knowledge, attitudes, and practices following the implementation of a complementary medicine practice guideline
AbstractPurposeComplementary medicine (CM) use is prevalent among cancer patients, yet it is often not assessed by oncology healthcare providers (HCPs). The purpose of this study was to evaluate oncology HCPs ’ knowledge, attitudes, and practices surrounding CM use before and after the implementation of a practice guideline focusing on standardizing assessment and documentation of CM.MethodsOncology HCPs across a provincial cancer agency were invited to participate in the study. The implementation strategy included an initial education session for HCPs and standardized CM assessment forms. Pre-post surveys assessing ...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Is sleep associated with BMI, waist circumference, and diet among long-term colorectal cancer survivors? Results from the population-based PROFILES registry
ConclusionSleep problems are common in long-term CRC survivors; however, sleep quality and duration was not associated with BMI, WC, and diet quality in this population. It is unknown why the results differ from findings in the general population. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Perspectives of health care providers referring patients to a newly implemented sexual health program in a Canadian cancer center
ConclusionSurvey results highlight the need for consistent program dissemination efforts to equip health care providers with accessible  patient education materials and easily implemented referral procedures. Importantly, providers indicated that they were more likely to raise the topic of sexuality with patients because they had somewhere to refer patients who had sexual concerns. Overall, findings inform efforts to implement sex ual health programming within cancer care institutions. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

The application of “Omics” to accelerate precision medicine in Supportive Care in Cancer
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Commentary: Quality nutrition care is integral to the Oncology Care Model
AbstractThe Oncology Care Model (OCM) is a US Centers for Medicare& Medicaid Services (CMS) specialty model implemented in 2016, to provide higher quality, more highly coordinated oncology care at the same or lower costs. Under the OCM, oncology clinics enter into payment arrangements that include financial and performance accountability for patients receiving chemotherapy treatment. In addition, OCM clinics commit to providing enhanced services to Medicare beneficiaries, including care coordination, navigation, and following national treatment guidelines. Nutrition is a component of best-practice cancer care, yet it m...
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Fertility discussions in young adult stage III colorectal cancer population: a single-center institution experience
AbstractPurposeColorectal cancer (CRC) is a malignancy that usually occurs in older age individuals. However, CRC cases in young adults are on the rise, and this increase is expected to continue. Young adult CRC requires the healthcare team to familiarize themselves with the unique needs of this population, including concerns about treatment-related infertility. We performed a retrospective review to determine how often our patients, 18 –39 years old (yo), had discussions regarding fertility preservation prior to starting stage III CRC treatment.MethodsOur electronic health record was utilized to identify adult patients  
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Correction to: Effectiveness of naloxegol in patients with cancer pain suffering from opioid ‑induced constipation
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - October 26, 2021 Category: Cancer & Oncology Source Type: research

Untangling the relationship between negative illness perceptions and worse quality of life in patients with advanced cancer —a study from the population-based PROFILES registry
AbstractPurposeQuality of life (QoL) is an important yet complex outcome of care in patients with advanced cancer. QoL is associated with physical and psychosocial symptoms and with patients ’ illness perceptions (IPs). IPs are modifiable cognitive constructs developed to make sense of one’s illness. It is unclear how IPs influence patients’ QoL. A better understanding of this relationship can inform and direct high quality care aimed at improving patients’ QoL. We therefore inv estigated the mediating role of anxiety and depression in the association of IPs with QoL.MethodsData from 377 patients wi...
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Unmet support needs in teenage and young adult childhood brain tumour survivors and their caregivers: “it’s all the aftermath, and then you’re forgotten about”
ConclusionsEven many years after diagnosis, TYA childhood brain tumour survivors and their caregivers continue to have unmet supportive care needs. Both TYA survivors and their caregivers can benefit from support to meet their unique needs and improve long-term quality of life. Understanding unmet needs and recognising what services are required due to the late effects of treatment is critical to improving long-term quality of survival. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

The chain mediating role of social support and stigma in the relationship between mindfulness and psychological distress among Chinese lung cancer patients
AbstractPurposePsychological distress greatly impaired the psychological and physical well-being of lung cancer patients. Identification of protective and risk factors is a prerequisite of developing effective psychological treatment protocol. The study aims to determine the relationship of mindfulness and psychological distress and further clarify the mechanism of mindfulness against psychological distress through perceived stigma and social support among Chinese lung cancer patients.MethodA cross-sectional survey study involving 441 valid Chinese lung cancer patients was conducted from September 2018 to August 2019. Afte...
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Fatigue is independently associated with functional status limitations in older adults with gastrointestinal malignancies —results from the CARE registry
ConclusionsOver half of older adults with cancer reported moderate to severe fatigue that was independently associated with functional status limitations. Further understanding of the multifaceted aspects of fatigue and development of interventions combating fatigue in this population is urgently needed. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Psychological interventions for enhancing resilience in parents of children with cancer: a systematic review and meta-analysis
ConclusionEvidence supports the effectiveness of psychological interventions for enhancing resilience in the parents of children with cancer. Healthcare professionals can incorporate evidence-based psychological interventions to enhance resilience to help these parents better navigate adversity, adapt to their children ’s situations and improve their psychological well-being. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Greater preferences for death in hospital and mechanical ventilation at the end of life among non-whites recently diagnosed with cancer
ConclusionNon-white cancer patients were more likely to express preferences coinciding with aggressive EOL care including dying at the hospital and utilizing mechanical ventilation. These findings were independent of other sociodemographic characteristics, including decisional self-efficacy. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Plasminogen activator inhibitor-1 gene promoter 4G/5G polymorphism and risks of peripherally inserted central catheter –related venous thrombosis in patients with lung cancer: a prospective cohort study
ConclusionOur finding suggested that there is no statistically significant influence of the PAI-1 4G/5G gene variant on PICC-RVT in Chinese patients with lung cancer. However, patients with higher Caprini scores and higher fibrinogen levels are at increased risk for PICC-RVT, as are patients receiving chemotherapy. Clinical staff should carefully perform a risk assessment for patients with PICC. Those with the above risk factors should pay close attention and take timely and effective preventive measures. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Recall, perceptions and determinants of receiving physical activity advice amongst cancer survivors: a mixed-methods survey
ConclusionThere is scope to improve the provision of physical activity advice in cancer care by providing advice in a timely manner after diagnosis, referring patients to a suitable exercise or rehabilitation specialist when indicated, and using a tailored approach to ensure the advice is appropriate for specific sociodemographic groups. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Medical cannabis in pediatric oncology: a survey of patients and caregivers
ConclusionsOur survey shows that cannabis, mostly oil products, was used by one-fifth of children with cancer during or after the completion of cancer treatment. These findings require validation in a larger nationwide survey. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research

Pegfilgrastim for primary prophylaxis of febrile neutropenia in multiple myeloma
AbstractMultiple myeloma (MM) survival rates have been substantially increased thanks to novel agents that have improved survival outcomes and shown better tolerability than treatments of earlier years. These new agents include immunomodulating imide drugs (IMiD) thalidomide and lenalidomide, the proteasome inhibitor bortezomib (PI), recently followed by new generation IMID pomalidomide, monoclonal antibodies daratumumab and elotuzumab, and next generation PI carfilzomib and ixazomib. However, even in this more promising scenario, febrile neutropenia remains a severe side effect of antineoplastic therapies and can lead to ...
Source: Supportive Care in Cancer - September 28, 2021 Category: Cancer & Oncology Source Type: research