Association of change in health-related quality of life and treatment discontinuation in metastatic breast cancer: a post hoc, exploratory analysis of two randomized clinical trials
ConclusionChanges in QOL are associated with the probability of treatment alteration among metastatic breast cancer patients. Physical functioning, role functioning, global health status, dyspnea, and fatigue should be prioritized for symptom management in patients with metastatic breast cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

A randomised controlled trial investigating the ability for supervised exercise to reduce treatment-related decline in adolescent and young adult cancer patients
ConclusionThe exercise intervention produced superior improvements in strength and global QOL, compared with the CG. Regardless of group allocation, enrolment in the exercise study appeared to mitigate the treatment-related decline expected in AYA undergoing cancer treatment. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Financial toxicity in female patients with breast cancer: a national cross-sectional study in China
ConclusionsFinancial toxicity and coping strategies are common among Chinese women with breast cancer. An understanding of the factors regarding financial toxicity may help oncologists and policy-makers identify at-risk patients and develop targeted interventions. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Risks, diagnosis, and management of recurrent cancer-associated thrombosis (CAT): a narrative review
AbstractThis paper aims to provide a narrative review of the risks, diagnosis, and management of recurrent venous thromboembolism (VTE) in cancer patients. There is an established association between cancer and VTE, with cancer being a major risk factor for VTE. A history of VTE, short duration of oral anticoagulation, and a proximal DVT are all associated with increased risk for recurrent VTE. Studies have shown that certain cancers (e.g., metastatic genitourinary, lung, and colorectal cancers) are associated with recurrent VTE. Published literature shows that cancer is prothrombotic, and various mechanisms have been post...
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Pattern of nutritional status in node-negative versus node-positive head and neck cancer patients undergoing treatment: a prospective cohort study
ConclusionAs compared to N0, N  + patients had higher burden of malnutrition at diagnosis, and more worsening of nutritional parameters during treatment. More decline in nutritional status was seen in patients receiving multi-modality as compared to single-modality treatment. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

A prospective study to evaluate febrile neutropenia incidence in patients receiving pegfilgrastim on-body injector vs other choices
ConclusionPatients receiving pegfilgrastim OBI had a lower incidence of FN compared with those receiving alternatives. The OBI was associated with improved adherence to and compliance with clinically recommended G-CSF prophylaxis. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

The clinical application value of phase angle of six parts in nutritional evaluation of tumor patients
ConclusionThe PA-WB is an independent prognostic factor of malnutrition. The prediction model constructed by age, BMI, and PA-WB can be used as a useful tool for nutritional evaluation of tumor patients.Trial registrationClinical Trial No.: ChiCTR2100047858. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Community-based interventions designed to optimize health behaviors among cancer survivors: an integrative systematic review
ConclusionThe current studies have built on the strengths and resources of the community using existing programs. There was a lack of diversity in socioeconomic status and racial/ethnic background among participants of most interventions and inputs from partners such as cancer survivors, community, and healthcare organizations. Multiple health behavior interventions with longitudinal studies are needed for racial/ethnic minoritized cancer survivors. Future research should focus on achieving mutual benefits through iterative processes to develop sustainable community/research partnerships, ensuring long-term commitment, and...
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Anxiety, depression, health-related quality of life, and mortality among colorectal patients: 5-year follow-up
ConclusionsThese findings should enable preventive follow-up programs to be established for such patients in order to reduce their psychological distress and improve their HRQoL to as great an extent as possible.ClinicalTrials.gov Identifier:NCT02488161 (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Factors influencing scalp cooling discussions and use at a large academic institution: a single-center retrospective review
ConclusionThere were distinctions in the types of patients who have documented discussions about SCT. Improving patient knowledge about the availability of SCT and increasing access to this technology for all eligible cancer patients may enable more patients to achieve improved quality of life by reducing or preventing CIA. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Acneiform eruptions with combination targeted cancer therapy in colorectal cancer patients
ConclusionThis is the first descriptive analysis to characterize acneiform eruptions for patients with colorectal cancer on combination cancer therapy. Approximately 85% of patients developed a cutaneous toxicity with what appears to be synergistic effects of EGFRI and MEKI combination therapy causing the most severe eruptions. Superinfection rate correlated to systemic therapy use beyond oral tetracyclines. Further investigation into the utility of prophylactic oral tetracyclines in this population is needed. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

The intention to get COVID-19 vaccine and vaccine uptake among cancer patients: An extension of the theory of planned behaviour (TPB)
AbstractThe psychosocial impact of coronavirus disease 2019 (COVID-19) on human life is well-known. Although vaccine protection represents an effective way to control the spread of the virus, vaccination hesitancy may decrease individuals ’ willingness to get vaccinated, including among cancer patients. Therefore, the objective of the current study was to examine the predictors of cancer patients’ intentions to receive COVID-19 vaccinations and vaccine uptake, using and integrating the theory of planned behaviour (TPB) and the he alth belief model (HBM). A sample of 276 Italian cancer patients (54% female and 46% male)...
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Letter to the Editor: The possible role of lymphadenopathy after vaccination in posttraumatic stress disorder in cancer survivors during COVID-19
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Correspondence re MASCC evidence-based recommendations for the management of malignant bowel obstruction
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research

Introduction to practical aspects of cancer-associated thrombosis and related complications
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - September 26, 2022 Category: Cancer & Oncology Source Type: research