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The mediating role of spirituality (meaning, peace, faith) between psychological distress and mental adjustment in cancer patients
ConclusionsThe Spanish version of the FACIT-Sp scale is a reliable and valid clinical evaluation tool, and further highlights the potential clinical implications of spirituality for improving quality of life and adjustment to cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Patient-clinician communication among patients with stage I lung cancer
AbstractPurposeLimited data exist about patient-centered communication (PCC) and patient-centered outcomes among patients who undergo surgery or stereotactic body radiation therapy (SBRT) for stage I non-small cell lung cancer (NSCLC). We aimed to examine the relationship between PCC and decision-making processes among NSCLC patients, using baseline data from a prospective, multicenter study.MethodsPatients with stage 1 NSCLC completed a survey prior to treatment initiation. The survey assessed sociodemographic characteristics, treatment decision variables, and patient psychosocial outcomes: health-related quality of life ...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Incongruence in treatment decision making is associated with lower health-related quality of life among prostate cancer survivors: results from the PiCTure study
ConclusionsLess than 6 in 10 PCa survivors experienced congruence between their actual and preferred roles in TDM. Having an incongruent TDM experience was associated with lower gHRQoL among survivors. These findings suggest that involving patients in TDM to the degree to which they want to be involved may help improve PCa survivors ’ gHRQoL. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Demographic, clinical, lifestyle-related, and social-cognitive correlates of physical activity in head and neck cancer survivors
ConclusionsDespite significant pathways of the TPB model, the large proportion variance in PA intention and behavior remaining unexplained suggests the need for better PA behavior (change) models to guide the development of PA promotion programs, particularly for the elderly. Such programs should be tailored to comorbidities and nutritional status. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Antimicrobial therapy in palliative care: an overview
AbstractIn the advanced stages of illness, patients often face challenging decisions regarding their treatment and overall medical care. Terminal ill patients are commonly affected by infections. However, in palliative care, the use of antimicrobials can be an ethical dilemma. Deciding whether to treat, withhold, or withdraw the antimicrobial treatment for an infection can be difficult. Antimicrobial administration can lead to adverse outcomes but the two main benefits, longer survival and symptom relief, are the main reasons why physicians prescribe antimicrobial when treating terminally ill patients. For the patient who ...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Breast cancer survivors: return to work and wage loss in selected hospitals in Malaysia
ConclusionsNon-RTW and wage loss after diagnosis of BC may result in the survivors experiencing a significant financial burden. Assessment of these patients is becoming more crucial because more women participate in the workforce in Malaysia nowadays and because BC is managed using multiple treatment modalities with their consequences could lead to long absences from work. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Burden of oral mucositis in stem cell transplant patients —the patients’ perspective
AbstractPurposePurpose of this study was to determine the impact of Oral Mucositis (OM) on health-related quality of life (HRQoL) and quality of life associated symptoms and functions in patients undergoing hematopoietic stem cell transplantation (HSCT).MethodsProspective, non-interventional single-center observational study at a German tertiary teaching hospital. Inpatient allogenic and autologous stem cell transplant patients ≥18-year-old with high-dose chemotherapy. OM was assessed with the WHO Oral Toxicity Scale, pain according to the Numeric Rating Scale (NRS) and the performance status using the ECOG Score. QOL w...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster —a retrospective cohort study
AbstractPurposeOncological care of advanced cancer patients was provided by multiple departments in Hong Kong. One of these departments, the clinical oncology department (COD), introduced systematic palliative care training for its oncologists since 2002. The COD was recognized as a European Society for Medical Oncology (ESMO) Designated Centre of Integrated Oncology and Palliative Care since 2009. This retrospective cohort study aims to review the impact of integrative training and service on palliative care coverage and outcome.MethodsClinical information, palliative service provision, and end-of-life outcomes of patient...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Photodynamic therapy for periungual pyogenic granuloma-like during chemotherapy: our preliminary results
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Evaluation of quality of life in caregivers who are providing home care to cancer patients
ConclusionThe quality of life of caregivers is very low. Each characteristic of the caregiver will affect the care he/she gives. From this point of view, it is important to consider the characteristics of caregivers in improving the care given to cancer patients. In this respect, there is a need to support caregivers both materially and spiritually. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Financial toxicity and symptom burden: what is the big deal?
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Physical activity among cancer survivors —what is their perception and experience?
ConclusionOn the one hand, the information requirements of tumour patients with respect to PA have not been adequately taken into account by practitioners. On the other hand, there are still subjective inhibitions on the part of the patients, which keep them from engaging in PA. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Fractures frequently occur in older cancer patients: the MD Anderson Cancer Center experience
In this study, among 304 patients with gastrointestinal, urologic, breast, lung, and gynecologic cancers we evaluated, and who completed the bone density testing (n = 199), 80% had osteoporosis or low bone mass (osteopenia). There was a higher prevalence of osteoporosis in cancer patients (40 vs. 16%,p = 0.05) than in population studies. Vitamin D insufficiency (
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Phase II study of palonosetron, aprepitant and dexamethasone to prevent nausea and vomiting induced by multiple-day emetogenic chemotherapy
ConclusionsThe examined combination antiemetic therapy was effective and well-tolerated in patients with TGCTs receiving 5-day cisplatin-based combination chemotherapy. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Extended nursing for the recovery of urinary functions and quality of life after robot-assisted laparoscopic radical prostatectomy: a randomized controlled trial
AbstractPurposeThe purpose of this work is to explore the effects of continuing nursing care intervention on postoperative urinary control and quality of life among patients with prostate cancer.MethodsThis was a single-center, parallel, and randomized controlled trial that was carried out at the Department of Urology, the First Affiliated Hospital of Anhui Medical University, China. The participants underwent robot-assisted laparoscopic radical prostatectomy (RARP) between October 2014 and April 2016. The patients were randomized to the experimental and control groups (n=37/group). Patients in the control group received r...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Tunneled pleural catheter use for pleural palliation does not increase infection rate in patients with treatment-related immunosuppression
ConclusionsThese results suggest that antineoplastic therapy may not significantly increase the overall risk of TPC-related infections, as the rate remains low and comparable to rates in patients not undergoing antineoplastic therapy. Regardless of immune status, the presence of a catheter-related infection did not negatively impact overall survival. These results should reassure clinicians that the need to initiate antineoplastic therapy should not delay definitive pleural palliation with a TPC. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Levofloxacin for febrile neutropenia prophylaxis in acute myeloid leukemia patients associated with reduction in hospital admissions
ConclusionsPrescribing oral levofloxacin post-consolidation chemotherapy in AML patients is associated with a reduction in febrile neutropenia. Further research is required to identify the impact on fluoroquinolone resistance and risk of CDAD. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Efficacy and safety of reinfusion of concentrated ascitic fluid for malignant ascites: a concept-proof study
AbstractPurposeMalignant ascites is one of the symptoms causing discomfort in advanced cancer patients. Cell-free and concentrated ascites reinfusion therapy (CART) is one treatment modality, but controlled trials are limited. The primary aim of this study was to explore the efficacy and safety of CART, as well as their predictors, to obtain data for planning a further controlled trial.MethodsThis was a single center retrospective cohort study in patients with refractory malignant ascites. Consecutive adult patients who underwent CART were enrolled. The primary endpoints were the time to next paracentesis and seven patient...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

The impact of remission status on patients ’ experiences with acute myeloid leukemia (AML): an exploratory analysis of longitudinal patient-reported outcomes data
AbstractPurposeShared decision-making in acute myeloid leukemia (AML) requires understanding patients ’ longitudinal experiences of illness, but little is known about the impact of remission status on patient-reported outcomes (PROs). We aimed to explore the association between remission status and PROs 6–12 months following induction chemotherapy.MethodsForty-two patients completed three validated instruments characterizing symptom burden (Patient Care Monitor v2.0), distress (NCCN Distress Thermometer), and QOL (FACT-Leu), as part of a longitudinal observational study. We used regression models to explor...
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Comparison of the MASCC and CISNE scores for identifying low-risk neutropenic fever patients: analysis of data from three emergency departments of cancer centers in three continents
ConclusionBoth MASCC and CISNE scores have reasonable discriminatory value in predicting patients with low-risk febrile neutropenia. Risk scores should be used in conjunction with clinical judgment for the identification of patients suitable for outpatient management of neutropenic fever. Developing more accurate scores, validated in prospective settings, will be useful in facilitating more patients being managed in an outpatient setting. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - March 29, 2018 Category: Cancer & Oncology Source Type: research

Wide-ranging impacts reported by NZ cancer survivors: is supporting cancer survivor resilience a health sector role?
ConclusionsThis study generated qualitative data on survivorship impacts and components of survivor resilience in NZ. It also provided insights into the need for better strategies and pathways to help the NZ health system be more responsive to both M āori and non-Māori survivors.Implications for cancer survivorsSurvivor impacts create vulnerabilities that are experienced and described differently by individuals and groups in NZ. Tailored survivor support that can enhance resilience and support relationships is needed in NZ. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

A discrete choice experiment to assess cancer patients ’ preferences for when and how to make treatment decisions
AbstractPurposeCancer patients can be overwhelmed when being confronted with their diagnosis and treatment options. Such information is often provided during one consultation between the patient and treating clinician. In order to achieve optimal cancer care, there may be justification for alternative consultation styles. We assessed, in a sample of adult medical oncology patients, their preferences for (i) attending one 40-min consultation or two 20-min consultations and (ii) receiving written only or both written and online information, when making a cancer treatment decision.MethodsThis was a cross-sectional survey usin...
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Adolescent-young adults (AYA) with cancer seeking integrative oncology consultations: demographics, characteristics, and self-reported outcomes
ConclusionAYA patients make up a small number of overall referrals to an IO consultation, presenting with a low to moderate symptom burden. Physical CIM interventions such as yoga and pilates are of greater interest to the AYA population, suggesting the importance of making such interventions available in cancer programs serving this population. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Systemic and local effects of vaginal dehydroepiandrosterone (DHEA): NCCTG N10C1 (Alliance)
AbstractBackgroundDehydroepiandrosterone (DHEA) is helpful for treating vaginal symptoms. This secondary analysis evaluated the impact of vaginal DHEA on hormone concentrations, bone turnover, and vaginal cytology in women with a cancer history.MethodsPostmenopausal women, diagnosed with breast or gynecologic cancer, were eligible if they reported at least moderate vaginal symptoms. Participants could be on tamoxifen or aromatase inhibitors (AIs). Women were randomized to 3.25 versus 6.5  mg/day of DHEA versus a plain moisturizer (PM) control. Sex steroid hormone levels, biomarkers of bone formation, vaginal pH, and m...
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Objective and subjective financial burden and its associations with health-related quality of life among lung cancer patients
ConclusionHealthcare costs exceeding total annual household income and perceived financial difficulty are associated with poorer HRQOL in lung cancer patients. Subjective indicator of financial burden has a stronger effect on quality of life than objective indicators.ImplicationHealth-cost-to-income ratio and perceived financial difficulty can be implied as objective and subjective indicators of financial burden to identify the patients who may need additional assistance. Communication on deciding on cost-effective treatments can be facilitated. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset
ConclusionPatients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Patient-reported physical activity and the association with health-related quality of life in head and neck cancer survivors
This study aimed to assess patient-reported levels of physical activity (PA) and its associations with health-related quality of life (HRQoL) adjusted for important demographic, lifestyle-related, and clinical factors, among head and neck (HNC) survivors.MethodsThis cross-sectional study included 116 HNC survivors. PA was assessed with the Physical Activity Scale for the Elderly (PASE) and HRQoL with the EORTC-QLQ-C30 and EORTC-HN35. Associations were studied using univariable and multivariable regression analyses.ResultsMedian PASE score was 100.3 (interquartile range 65.1;170.8) of which 54% were household, 34% leisure-t...
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Denosumab versus bisphosphonates in patients with advanced cancers-related bone metastasis: systematic review and meta-analysis of randomized controlled trials
ConclusionDenosumab showed a favorable significant impact on delaying the time to first skeletal-related event and reducing the incidence of radiation to the bone event in comparison to bisphosphonates, with similar efficacy regarding overall survival and time to disease progression. Further large-scale and long-term studies are needed to clarify the long-term efficacy and safety of both regimens. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Serotonin transporter polymorphism, depressive symptoms, and emotional impulsivity among advanced breast cancer patients
This study tested a theory linking a marker of low serotonergic function to both depression and impulsivity in a sample of advanced breast cancer patients, among whom elevated depressive symptoms and difficulty regulating emotions are commonly reported.MethodsA total of 95 patients provided blood samples for serotonin transporter polymorphic region of the gene (5-HTTLPR) and completed questionnaires that measured depressive symptoms and emotional impulsivity.ResultsStructural equation modeling revealed that thes allele of 5-HTTLPR was related to greater depressive symptoms (β = .20,p 
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Oncology navigators ’ perceptions of cancer-related financial burden and financial assistance resources
ConclusionOncology navigators reported a high burden of financial toxicity among their patients but insufficient knowledge or resources to address this need. This study underscores the importance of improved training and coordination for addressing financial burden, and the need to address community and system-level barriers. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Triadic treatment decision-making in advanced cancer: a pilot study of the roles and perceptions of patients, caregivers, and oncologists
ConclusionsPatients, caregivers, and oncologists have discordant perceptions of the cancer treatment decision-making process, and bring different preferences about how they want to make decisions. These data suggest that oncologists should assess patients ’ and caregivers’ decisional preferences, explicitly signal that a decision needs to be made whenever approaching an important crossroads in treatment and ensure that patients and caregivers understand the full range of presented options. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

The distress thermometer in survivors of gynaecological cancer: accuracy in screening and association with the need for person-centred support
ConclusionsIn gynaecological cancer survivors, DT may perform fairly well as a first stage screening tool for distress, but a second stage is likely needed due to a high number of false positives. DT and HADS scores may predict the number of supportive conversations needed in an individualised intervention in gynaecological cancer survivors. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Preventing chemotherapy-induced nausea and vomiting in patients with lung cancer: efficacy of NEPA (netupitant-palonosetron), the first combination antiemetic
ConclusionsNEPA appears to be effective and well tolerated in patients with lung cancer receiving platinum-based chemotherapy, across the acute, delayed, and overall phases and throughout multiple cycles. As a highly effective oral combination antiemetic agent administered as a single dose once per cycle, NEPA may offer a convenient, simplified prophylactic antiemetic. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Building psychosocial capacity through training of front-line health professionals to provide brief therapy: lessons learned from the PROMPT study
ConclusionPsychosocial care can be provided by a range of health professionals if they receive focused training and have access to supervision, but competing clinical demands are likely to limit their ability to routinely provide psychosocial care. This suggests that training should target professionals who have greater autonomy and flexibility in their work roles.Trial registration numberANZCTR1260000448044 (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Physical interventions for patients suffering from chemotherapy-induced polyneuropathy
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Caregiver social support quality when interacting with cancer survivors: advancing the dual-process model of supportive communication
AbstractCancer caregivers often experience significant challenges in their motivation and ability to comfort cancer survivors, particularly in a spousal or romantic context. Spousal cancer caregivers have been known to report even greater levels of burden and distress than cancer sufferers, yet still take on the role of acting as an informal caregiver so they can attend to their partner ’s needs. The current study tested whether a theoretical model of supportive outcomes—the dual-process model of supportive communication—explained variations in cancer caregivers’ motivation and ability to create hig...
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Factors influencing non-participation in an exercise program and attitudes towards physical activity amongst cancer survivors
ConclusionsInterventions aimed at promoting physical activity in cancer survivors should offer home-based programs and include referral and advice from oncologists.Implications for cancer survivorsIncreasing cancer survivors ’ participation in, and compliance with, exercise programs may require home-based strategies and referrals from oncologists to allied health professionals to individualise care. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients
ConclusionExercise training is feasible in patients with colorectal cancer after completion of adjuvant chemotherapy. The main problem encountered during the study was compliance. To improve compliance of exercise training, several measures were adapted for the upcoming prospective randomized ABCSG C08 Exercise II study. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Unmet support needs of sexual and gender minority breast cancer survivors
ConclusionThis study provides quantitative and qualitative evidence that many SGM breast cancer patients face a dearth of appropriate social supports, both from breast cancer survivor organizations and from within the medical system. These findings confirm the need for research on the physical and emotional effects of breast cancer treatment on SGM breast cancer survivors, as well as further exploration of the social support needs and experiences of SGM breast cancer patients and their partners. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Goshajinkigan for prevention of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis
ConclusionsGoshajinkigan is unlikely to prevent CIPN in patients undergoing neurotoxic chemotherapy. Given the low quality and insufficient amount of the evidence, use of goshajinkigan as standard of care is not currently recommended. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: research

Short-term follow-up of the nutritional status of children with Fanconi anemia undergoing hematopoietic stem cell transplant
The objective of this study was to evaluate the nutritional status of children diagnosed with Fanconi anemia (FA) during hematopoietic stem cell transplant (HSCT), comparing it with healthy children and children with other hematologic diseases.MethodsObservational retrospective study was conducted with patients submitted to HSCT in a period of 5  years. We assessed anthropometric and biochemical data, food intake, and gastrointestinal complications in 49 FA patients. We compared the anthropometric information with those of transplanted patients with other diagnoses (n = 54) in three periods (pre-transplant, ...
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Relationship between phase I study duration and symptom burden
AbstractPurposePhase I clinical trials are critical to development of cancer therapeutics. Adverse events (AEs) and symptom burden contribute to early treatment withdrawal, and it is often difficult to ascertain whether these events are disease- or treatment-related. Regardless, early withdrawal may delay determination of the effectiveness of potential new therapies. We sought to characterize the reasons for early treatment termination to identify potential modifiable events.MethodsA retrospective chart review was conducted on solid tumor patients enrolled in institutional phase I clinical trials from 2003 to 2013 through ...
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Palliative care content on cancer center websites
ConclusionsCancer center homepages rarely mention palliative care services. While the majority of centers have webpages with palliative care content, they sometimes omit information about early use of care. Improving accessibility of palliative care information and increasing emphasis on early provision of services may improve integration of palliative and cancer care. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Defibrotide for the treatment of sinusoidal obstruction syndrome: evaluation of response to therapy and patient outcomes
AbstractPurposeDefibrotide is an agent used to treat sinusoidal obstruction syndrome (SOS/VOD) in patients undergoing haemopoietic stem cell transplantation. The aim of this study was to evaluate the effectiveness of defibrotide used within institutional guidelines for the treatment of SOS/VOD in patients undergoing haemopoietic stem cell transplantation (HSCT).MethodsData for 23 patients was retrospectively reviewed to evaluate the effectiveness of defibrotide and the utility of response criteria to direct therapy as specified within institution guidelines. Patients met institutional criteria for a diagnosis of SOS/VOD ba...
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Risk factors and reasons for treatment abandonment among children with lymphoma in Malawi
We examined risk factors and reasons for treatment abandonment for this population in Malawi.MethodsWe conducted a mixed methods study among children
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Utilization of agents to prevent skeletal-related events among patients with multiple myeloma: analysis of real-world data
ConclusionsThese results highlight the possibility of suboptimal prevention of skeletal-related events due to non-compliant dosing and non-persistence after patients initiate BTA therapy. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Assessing the utility of a distress screening tool at capturing sexual concerns in a gyne-oncology follow-up clinic
ConclusionsThese results call into question the utility of the intimacy/sexuality item on the Canadian Problem Checklist to identify gynecological cancer patients who have sexual concerns. Furthermore, even among those patients who indicated concerns, there is evidence that their problems are rarely addressed. Providers need to directly inquire with patients about their sexual health. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Efficacy and safety of 153 Sm-EDTMP as treatment of painful bone metastasis: a large single-center study
Conclusion153Sm-EDTMP therapy is an effective supportive treatment in patients who suffer from bone metastases, especially in patients with breast or prostate cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Safety and cost benefit of an ambulatory program for patients with low-risk neutropenic fever at an Australian centre
ConclusionOf relevance to hospitals providing cancer care, feasibility, safety, and cost benefits of an ambulatory program for low-risk NF patients have been demonstrated. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research

Impact of body composition on outcome in patients with early breast cancer
ConclusionsSarcopenia and IMAT index are independent prognostic factors in early breast cancer; therefore, assessing body composition could be a simple and useful approach to integrate into patient management. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 25, 2018 Category: Cancer & Oncology Source Type: research