The prevalence of patient-reported dysphagia and oral complications in cancer patients
ConclusionsThis is the first time comprehensive data on dysphagia and oral complications across all cancer patients have been collected. We have identified that dysphagic symptoms and oral complications —which have implications for quality of life and function—are common in all cancer patients, not just those with head and neck cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Management of bone health in patients with cancer: a survey of specialist nurses
ConclusionThis work is the first quantitative analysis of reports from specialist oncology nurses about the management of bone metastases and CTIBL. It indicates the need for new nursing education initiatives with a focus on bone health management. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Novel hyaluronan formulation for preventing acute skin reactions in breast during radiotherapy: a randomized clinical trial
ConclusionsWe found a nonstatistically significant patient preference but overall no significant radioprotective effects for this HA formulation compared with placebo except in patients with larger breasts.Trial registrationThe study was registered atwww.clinicaltrials.gov (NCT02165605). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial
This study accrued 50 patients, 25 to each of the 2 study arms; 46 patients were evaluable. There were twice as many Scrambler-treated patients who had at least a 50% documented improvement during the 2 treatment weeks, from their baseline pain, tingling, and numbness scores, when compared with the TENS-treated patients (from 36 to 56% compared with 16 –28% for each symptom). Global Impression of Change scores for “neuropathy symptoms,” pain, and quality of life were similarly improved during the treatment weeks. Patients in the Scrambler group were more likely than those in the TENS group to recommend th...
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Mind-body medicine use by women diagnosed with breast cancer: results of a nationally representative survey
ConclusionsIn this nationally representative sample of the USA, the most common used MBM approach was spiritual meditation, while this approach is much less researched than the evidence based approaches of yoga and mindfulness meditation. Especially stressed individuals worldwide could benefit from MBM the literature suggests. Particularly in the acute survivorship stage, influencing the initial stress reaction could be beneficial. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Association of time to antibiotics and clinical outcomes in patients with fever and neutropenia during chemotherapy for cancer: a systematic review
ConclusionThere seems to be an association between longer TTA and impaired safety. More knowledge about TTA effects on safety are important to optimise treatment guidelines for FN. Controlling for triage and other biases is necessary to gain further evidence.Trial registrationRegistration: PROSPERO [http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018092948]. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

A retrospective analysis of the prevalence and clinical outcomes of vitamin D deficiency in myeloma patients in tropical Australia
ConclusionThere is a relatively high prevalence of vitamin D deficiency in patients with myeloma in our study. This is despite a sunlight heavy, tropical climate. We report an association between vitamin D deficiency and peripheral neuropathy. Prospective interventional trials are required to further assess this. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Symptom response analysis of a randomized controlled trial of reflexology for symptom management among women with advanced breast cancer
ConclusionsHome-based caregiver-delivered reflexology was helpful in decreasing patient-reported pain. Age, comorbid conditions, and depression are potentially important tailoring factors for future research and can be used to identify patients who may benefit from reflexology.Trial registrationClinicalTrials.gov Identifier: NCT01582971 (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Unmet needs in the physical and daily living domain mediates the influence of symptom experience on the quality of life of gastric cancer patients
This study aimed to understand the unmet needs of gastric cancer patients at different phases of the cancer journey, identify factors contributing to their unmet needs and quality of life (QOL) and explore the relationships among unmet needs, symptom experience, anxiety, depression, and QOL.MethodsA correlational study was conducted using data from 223 gastric cancer patients. The instruments include the SCNS-SF 34, HADS, MDASI, and EORTC QLQ-C 30 (Korean version). Descriptive statistics,t test/ANOVA, Pearson ’s correlation, multiple regression, and path analyses were used to analyze the data.ResultsUnmet needs in th...
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Advance care planning in glioblastoma patients: development of a disease-specific ACP program
ConclusionThis study resulted in an ACP program specifically for glioblastoma patients. Although participants agreed on the program content, the optimal timing of introducing such a program was a matter of debate. Our solution is to offer the program shortly after diagnosis but let patients and proxies decide which topics they want to discuss and when. The impact of the program on several patient- and care-related outcomes will be evaluated in the next step. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Modifications of taste sensitivity in cancer patients: a method for the evaluations of dysgeusia
ConclusionsCoping strategies regarding subjective taste impairment should be provided since alterations in taste sensitivity influence food preferences and appetite. Clinicians could thus have the potential to underpin changes in dietary intake and consequently in nutritional status; understanding the extent of the contribution of each taste would help in the development of effective interventions in future. Consequently, patients can adopt appropriate appetizing strategies and, based on that, change their feeding habits. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

First day of radiotherapy for women with breast cancer: predictors of anxiety
ConclusionOur findings highlight the need to identify women with moderate or higher levels of trait anxiety before radiotherapy initiation and to provide them with a more approach to personalized care, adjusted to their specific concerns and susceptibility to anxious reactions. Effective education sessions involving the discussion of specific treatment concerns, and anxiety coping strategies training should be developed and applied in initial interactions with breast cancer patients. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Epilepsy education in gliomas: engaging patients and caregivers to improve care
ConclusionStructured TRE education is feasible in patients with gliomas and their caregivers and may be effective in reducing distress. Further prospective studies are warranted to assess effects on hospitalizations, cost, and QOL. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Placebo therapy for cancer-related pain: an alternative to psychotherapy or health misinformation?
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Correction to: Enteral and parenteral nutrition in cancer patients, a comparison of complication rates: an updated systematic review and (cumulative) meta-analysis
The appendices were incorrectly numbered in the original article. Please see below correcct appendices (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Comments on “Prevalence of shoulder morbidity after treatment for breast Cancer in South Africa”
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Referral practices to dermatologists for the treatment of radiation dermatitis in the USA: a call for a multidisciplinary approach
This study evaluated the referral practices of radiation oncologists to dermatologists for management of RD utilizing a survey of radiation oncologists across the USA. The goal was to identify the referral practices of radiation oncologists for RD and any barriers to a multidisciplinary approach.ResultsOf the 705 respondents, 15% reported ever referring patients to dermatology. Private practitioners referred significantly less than providers in academic or oncology centers (p
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Correction to: effect of acupressure on constipation in patients with advanced cancer
The institutional review board number  is incorrect, it should be No. 104-3133B. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

Response to: “Caring for the person with cancer and the role of digital technology in supporting carers”
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: research

An immunotherapy survivor population: health-related quality of life and toxicity in patients with metastatic melanoma treated with immune checkpoint inhibitors
ConclusionsOur results show that metastatic melanoma survivors have potentially experienced significant ICI-related toxicity and experience significant impairments in specific HRQoL domains. Future service planning is required to meet this population ’s unique survivorship needs. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Development and evaluation of the Cancer Symptom Management System: Symptom Management Improves your LifE (SMILE) —a randomized controlled trial
ConclusionThe application of the Cancer Symptom Management System: SMILE incorporating ONS PEP –guided evidence-based symptom management education effectively managed fatigue and sleep disturbance after adjuvant CTx. The feasibility of the system has been demonstrated. Incorporating the system into electronic medical systems and integrating provider input will be necessary. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Religion as a determining factor for invasive care among physicians in end-of-life patients
ConclusionAbsence of religion is associated with higher invasive behaviors on the part of physicians. Further studies are needed to better define this relationship. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Lung cancer and family-centered concerns
ConclusionsFamily members of patients with lung cancer are interested in discussing risk factors, prevention, and diagnoses and also would like access to other supportive services do learn about and cope with some of the stresses and barriers they experience in the family lung cancer journey. The diagnosis represents a potential teachable moment with the opportunity to reduce the risk of LC development or improve early detection in LC patient ’s family members. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Sleep disturbance and cancer-related fatigue symptom cluster in breast cancer patients undergoing chemotherapy
ConclusionsThis study identified groups of breast cancer patients with differentially severe sleep disturbance and CRF symptom profiles prior to and during chemotherapy. Identifying groups with different symptom management needs and distinguishing groups by baseline sociodemographic/medical variables can identify patients at risk for greater symptom burden. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Profile of anemia in acute lymphoblastic leukemia patients on maintenance therapy and the effect of micronutrient supplementation
ConclusionTimely identification and correction of micronutrient deficiencies causing anemia in ALL patients on maintenance can enhance treatment outcomes. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Risk assessment of febrile neutropenia and evaluation of G-CSF use in patients with cancer: a real-life study
ConclusionsThe use of G-CSFs for FN prophylaxis is recommended; however, there may be a group of patients who are inadequately or unnecessarily treated. Therefore, patients should be assessed for the risk of developing FN in each cycle of chemotherapy and a regular risk assessment by using the PRS can be implemented in the monitoring process. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Usefulness of Kinect sensor –based reachable workspace system for assessing upper extremity dysfunction in breast cancer patients
AbstractPurposeRecently,the utility of the Kinect sensor –based reachable workspace analysis system for measuring upper extremity outcomes of neuromuscular and musculoskeletal diseases has been demonstrated. Here, we investigated its usefulness for assessing upper extremity dysfunction in breast cancer patients.MethodsTwenty unilateral breast cancer patients were enrolled. Upper extremity active range of motion was captured by the Kinect sensor, and reachable workspace relative surface areas (RSAs) were obtained. The QuickDASH was completed to assess upper extremity disability. General and breast cancer –specif...
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Primary care physicians ’ perspectives of the survivorship care for older breast cancer survivors: a pilot study
ConclusionPCPs indicated that survivorship care and SCPs should be improved, regarding communication and roles related to their patients ’ survivorship. PCPs should assume an active role to enhance PCP-oncologist communication. Future research in PCPs’ role in survivorship care in a broad, diverse cancer survivor population is warranted.Implications for cancer survivorsMore attention needs to focus on the importance of PCPs, as they are an integral part of dual management for older breast cancer survivors post-treatment. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

An in-hospital clinical care pathway with integrated decision support for cancer pain management reduced pain intensity and needs for hospital stay
ConclusionsThe interventions were implemented according to the intentions and PI was reduced as hypothesized. For evaluation of generalizability, the interventions should be studied in other settings and with a controlled design. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Educational video intervention improves knowledge and self-efficacy in identifying malnutrition among healthcare providers in a cancer center: a pilot study
AbstractPurposeCancer is the second leading cause of death in the USA, and malnutrition secondary to cancer progression and treatment side effects is common. While abundant evidence indicates that nutrition support improves patient outcomes, it is estimated that up to half of malnutrition cases are misclassified or undiagnosed. The use of a multidisciplinary team to assess nutrition status has been observed previously to reduce delays in nutritional support. Hence, educating all members of the oncology healthcare team to assess nutrition status may encourage earlier diagnosis and lead to improved patient outcomes. Thus, th...
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Differences in the health, mental health and health-promoting behaviours of rural versus urban cancer survivors in Australia
ConclusionsThere is a need for deeper understanding of the impact of relative socioeconomic disadvantage on health (particularly physical activity and obesity) in rural settings and the development of accessible and culturally appropriate interventions to address rural cancer survivors ’ specific needs and risk factors. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Health-related quality of life in adult patients with brain metastases after stereotactic radiosurgery: a systematic, narrative review
ConclusionsIn general, SRS does not have significant negative effects on patients ’ overall HRQoL over time. Future research is needed to analyze different aspects of HRQoL, differences in individual changes in HRQoL after SRS, and factors that influence these changes. These studies should take into account several methodological issues as discussed in this review. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Dressings for the central venous catheter to prevent infection in patients undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis
ConclusionsRegarding the type of the dressing, there is no evidence indicating the best dressing. Although there is no evidence available for the ideal replacement frequency, the risk to develop skin irritation is reduced in longer dressing replacements intervals. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

A pilot survey of ventilated cancer patients ’ perspectives and recollections of early mobility in the intensive care unit
ConclusionsVentilated cancer patients reported an overall positive EM experience, but factual memory impairment of EM activities was common. These findings highlight the needs and the importance of shaping strategies to deliver a more patient focused EM experience. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Letter to the editor: “Improving information to caregivers of cancer patients: the Herlev Hospital Empowerment of Relatives through More and Earlier information Supply (HERMES) randomized controlled trial”
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Could the impact of photobiomodulation on tumor response to radiation be effected by tumor heterogeneity?
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Letter to the Editor: Re: “Is heart rate variability a valuable method to investigate cardiac autonomic dysfunction in subjects with leukemia? A systematic review to evaluate its importance in clinical practice” by Kirizawa et al
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Considerations about heart rate variability in leukemia
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Response to Letter to the Editor: Improving information to caregivers of cancer patients: the Herlev Hospital Empowerment of Relatives through More and Earlier information Supply (HERMES) randomized controlled trial
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

The positive effect of workplace accommodations on the continued employment of cancer survivors five years after diagnosis
ConclusionsReceipt of workplace accommodations strongly increases the continued employment of cancer survivors 5 years after diagnosis. More research is needed to better understand the differences in receipt of workplace accommodations along with the related selection effect. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Patterns of granulocyte colony –stimulating factor prophylaxis in patients with cancer receiving myelosuppressive chemotherapy
ConclusionsThere is under- and mistimed use of PP-G-CSF among patients at HR for FN. Novel pegfilgrastim delivery devices could help breast cancer patients at HR for FN complete all their cycles with timely prophylaxis. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Response to Davies A, Leach C, Caponero R, Dickman A, Fuchs D, Paice J, Emmanuel A (2020) MASCC recommendations on the management of constipation in patients with advanced cancer. Support Care Cancer 28:23
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

Reply to: Olanzapine: Sancho Panza for clinicians who care for patients with advanced cancer
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 10, 2020 Category: Cancer & Oncology Source Type: research

The use of complementary medicine in palliative care in France: an observational cross-sectional study
ConclusionThis second survey on CM use in France; is the first conducted in palliative care centers. Results show people with cancer in Lyon, France, have a very high prevalence of CM utilization. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 9, 2020 Category: Cancer & Oncology Source Type: research

A nurse-led paediatric oncology fast-track clinic proves a successful ambulatory intervention for patients
ConclusionOur pilot study implementing an OFTC for the triage and assessment of chemotherapy-related complications has proven successful from an operational and consumer perspective. The clinic improved care by ensuring expedited review, more streamlined interventions, and less overall hospital admissions. The improvements in efficiency were also mirrored by increased parent and patient satisfaction. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 9, 2020 Category: Cancer & Oncology Source Type: research

Age and gender differences in financial distress among hematopoietic cell transplant survivors
This study examined age differences in financial distress in hematopoietic cell transplant survivors and whether these differences result from measurement bias, more financial barriers to care, or an overall higher level of distress.MethodsHematologic malignancy survivors (n = 1135, 2–10 years post-transplant) completed the Cancer and Treatment Distress Scale (CTXD) and demographics as part of the baseline assessment for a randomized clinical trial. The CTXD has seven subscales, but for this study, we examined the financial distress subscale and the overall scor e. Item response theory analyses tes...
Source: Supportive Care in Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: research

Oral cannabinoid for the prophylaxis of chemotherapy-induced nausea and vomiting —a systematic review and meta-analysis
ConclusionAlthough there exists some evidence suggesting that oral cannabinoids may have a role in controlling for emesis from a neurophysiological perspective, these conclusions are currently not mirrored in the published RCTs to date. However, there exists only a limited number of RCTs, comparisons with older treatment regimens and a lack of standard reporting practice across published literature. Further RCTs should investigate the efficacy and safety of oral cannabinoids, to secure a better picture of the efficacy of oral cannabinoids against CINV. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: research

Determining the prevalence and severity of cancer cachexia in advanced non-small cell lung cancer and its relationship with chemotherapy outcomes
ConclusionsLimited conclusions can be drawn given the small sample size. However, the majority of patients presented with some degree of cachexia at diagnosis. A relationship was identified between the increasing severity of cachexia and a lower number of chemotherapy cycles completed, as well as between CRP and the number of chemotherapy cycles completed and the number of dose reductions required, and therefore warrants further exploration in larger studies. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: research

Changes in body weight and serum liver tests associated with parenteral nutrition compared with no parenteral nutrition in patients with acute myeloid leukemia during remission induction treatment
ConclusionFrequent compared with exceptional use of PN in AML patients during RI treatment better preserved body weight, without clinically relevant (CTCAE grade 3 –4) elevations in serum LTs. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: research

Oral examination findings, taste and smell testing during and following head and neck cancer therapy
ConclusionsIn HNC patients, oral status and taste change occurs throughout the cancer trajectory and represent potential concerns in cancer survivorship. Taste change (as evaluated by taste testing) occurred in all HNC patients, whereas olfactory changes occurred in 30% of cases. Management of oral changes and symptoms should be considered in all HNC patients in addition to dietary and nutritional guidance in patient care to promote oral intake. Continuing study of taste changes may further define this problem and support dietary and nutritional guidance and product development. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - January 7, 2020 Category: Cancer & Oncology Source Type: research