Evaluation of chemotherapy-induced nausea and vomiting in pediatric patients with high-grade glioma treated with lomustine —a case series
ConclusionIn this case series, we identified lomustine as a highly emetogenic chemotherapeutic agent. According to the current guidelines, CINV prophylaxis with a 5-HT3 receptor antagonist in combination with dexamethasone and (fos)aprepitant is recommended. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 16, 2024 Category: Cancer & Oncology Source Type: research
A single-arm pilot of MyInspiration: a novel digital resource to support spiritual needs of patients undergoing cancer-directed surgery
ConclusionMyInspiration was feasible and acceptable to patients, and the majority were satisfied with the tool. The intervention was associated with changes in patients ’ ability to find meaning within their cancer experience. A randomized control trial is needed to evaluate the efficacy of the tool in a broader population of patients with cancer. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 16, 2024 Category: Cancer & Oncology Source Type: research
“Like not having an arm”: a qualitative study of the impact of visitor restrictions on cancer care during the COVID-19 pandemic
ConclusionsOur data demonstrate the tripartite structure of the therapeutic relationship in cancer care with caregivers providing critical support in the decision-making and care process to both patients and physicians. Caregiver absences led to practical, psychosocial, and informational burdens on both groups, and likely increased the risk of burnout among physicians. Our findings suggest that the quality of cancer care can be enhanced by engaging caregivers and promoting their physical presence during clinical encounters. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 16, 2024 Category: Cancer & Oncology Source Type: research
The impact of social support on benefit finding among patients with advanced lung cancer and their caregivers: based on actor-partner interdependence mediation model
ConclusionThere is an interaction between social support, hope level, and benefit finding in patients with advanced lung cancer and their primary caregivers. Healthcare professionals ought to be vigilant in recognizing patients and caregivers who are vulnerable, have limited social support, and possess diminished hope levels. At the same time, nurses should provide timely psychological support and counseling to patients and their caregivers, encourage them to actively participate in social activities, and inspire their confidence and hope in life, thus improving their benefit findings. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 15, 2024 Category: Cancer & Oncology Source Type: research
A qualitative study on experiences of stigma among postoperative oral cancer patients
ConclusionPostoperative oral cancer patients clearly articulated that stigma was present in their lives and they experienced multiple forms of stigma. Further work is needed to increase education and awareness about oral cancer to guide them to take positive coping and reduce stigma. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 13, 2024 Category: Cancer & Oncology Source Type: research
The use of interventional procedures for cancer pain. A brief review
ConclusionsFurthermore, this review identifies the need for a systematic and comprehensive approach to the management of cancer pain that is broader than that of a single specialty. With recent advances in pain management procedures, an interdisciplinary approach is essential in order to provide an up to date, patient tailored approach to pain management.This review will help inform the development of a cancer pain intervention registry. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
Perceived control, self-management efficacy, and quality of life in patients treated with radiation therapy for breast cancer: a longitudinal study
ConclusionThe QoL, perceived control, and self-efficacy of patients with breast cancer show dynamic changes during radiotherapy. The higher the self-efficacy, the better the QoL, and the worse the QoL when the sense of disease control is poor. At the same time, more attention should be paid to the QoL of breast cancer radiotherapy patients with a long course of the disease, receiving chemotherapy, and different medical payment methods. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
Increasing physical activity among older adults with gynecologic cancers: a qualitative study
ConclusionIn this study of older gynecologic cancer patients receiving chemotherapy, most were open to participating in a virtually accessible and symptom-tailored physical activity intervention to promote physical activity during chemotherapy. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 11, 2024 Category: Cancer & Oncology Source Type: research
Physical health-related quality of life trajectories over two years following breast cancer diagnosis in older women: a secondary analysis
ConclusionA large subgroup of older women reported very low PCS that did not improve over time. Older age, obesity, multiple comorbidities, and lower socioeconomic status may be risk factors for poorer PCS in women with breast cancer. Incorporating routine comprehensive geriatric assessments that screen for these factors may help providers identify older women at risk for poorer physical HRQoL post breast cancer treatment. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 11, 2024 Category: Cancer & Oncology Source Type: research
Frequency and characteristics of immune-related thyroid adverse events in patients with resected stage III/IV melanoma treated with adjuvant PD-1 inhibitors: a national cohort study
ConclusionsIrTAE is a common side effect to PD-1 inhibitors primarily occurring within the first 3 months, with a high risk of persistency. Female sex is a strong predictive factor. IrTAE was not associated with improved clinical outcome. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 10, 2024 Category: Cancer & Oncology Source Type: research
2020 ASCO, 2023 NCCN, 2023 MASCC/ESMO, and 2019 CCO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in cancer patients
AbstractChemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with various malignancies ranging from early to end stages. In light of frequent changes to the guidelines for optimal management of CINV, we undertook this narrative review to compare the most recent guidelines published by ASCO (2020), NCCN (2023), MASCC/ESMO (2023), and CCO (2019). The processes undertaken by each organization to evaluate existing literature were also described. Although ASCO, NCCN, MASCC/ESMO, and CCO guidelines for the treatment and prevention of CINV share many fundamental simi...
Source: Supportive Care in Cancer - April 10, 2024 Category: Cancer & Oncology Source Type: research
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study
ConclusionEven in a country where the costs of TKIs and follow-up care are covered by health insurance, financial difficulties can be present in GIST patients, especially in patients on TKI treatment, and may negatively influence the quality of life. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 10, 2024 Category: Cancer & Oncology Source Type: research
Efficacy of delayed pegfilgrastim administration following consolidation therapy with high-dose cytarabine (HiDAC) in acute myeloid leukemia (AML) patients
ConclusionA difference in time to neutrophil recovery was not observed between the early and delayed administration groups yet decreased infectious complications may support the delayed administration of pegfilgrastim in these patients. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 9, 2024 Category: Cancer & Oncology Source Type: research
Characterising vincristine-induced peripheral neuropathy in adults: symptom development and long-term persistent outcomes
ConclusionVIPN in adults presents as a sensorimotor, upper- and lower-limb neuropathy that significantly impacts disability and function. Neuropathy recovery occurs in a proportion of patients; however, VIPN symptoms may persist and continue to affect long-term quality of life. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 9, 2024 Category: Cancer & Oncology Source Type: research
Correction to: In the weeds: a retrospective study of patient interest in and experience with cannabis at a cancer center
(Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 9, 2024 Category: Cancer & Oncology Source Type: research
