A Predictive Model of Weight Loss After Roux-en-Y Gastric Bypass up to 5  Years After Surgery: a Useful Tool to Select and Manage Candidates to Bariatric Surgery
AbstractIntroductionDifferent factors, such as age, gender, preoperative weight but also the patient ’s motivation, are known to impact outcomes after Roux-en-Y gastric bypass (RYGBP). Weight loss prediction is helpful to define realistic expectations and maintain motivation during follow-up, but also to select good candidates for surgery and limit failures. Therefore, developing a realistic pred ictive tool appears interesting.Patients/MethodsA Swiss cohort (n = 444), who underwent RYGBP, was used, with multiple linear regression models, to predict weight loss up to 60 months after surgery conside...
Source: Obesity Surgery - June 19, 2018 Category: Surgery Source Type: research

Intestinal Glucose Absorption Was Reduced by Vertical Sleeve Gastrectomy via Decreased Gastric Leptin Secretion
ConclusionOur data demonstrated that the decreased secretion of gastric leptin in VSG results in a decrease in intestinal glucose absorption via modulation of GLUT2 translocation. (Source: Obesity Surgery)
Source: Obesity Surgery - June 18, 2018 Category: Surgery Source Type: research

Calibration of the Gastric Pouch in Laparoscopic Roux-en-Y Gastric Bypass: Does It Matter? The Influence on Weight Loss
ConclusionThe use of a calibration tube for creating the gastric pouch may lead to a higher %EWL and %TWL at 2-year follow-up. The standardization of the technique for LRYGB is desirable to achieve the maximum success rate in the surgical therapy of morbid obesity. (Source: Obesity Surgery)
Source: Obesity Surgery - June 18, 2018 Category: Surgery Source Type: research

Managing a Positive Air-Leak Test During a Gastrojejunostomy Revision
ConclusionsGastrojejunostomy revision is a complex procedure that requires an advanced bariatric surgery skills and experience. Omental patch can be used in cases where friable tissue anastomosis leaks as a sealant along with a protective feeding gastrostomy. (Source: Obesity Surgery)
Source: Obesity Surgery - June 18, 2018 Category: Surgery Source Type: research

Metabolic Surgery for the Treatment of Diabetes Mellitus Positioning of Leading Medical Associations in Mexico
ConclusionsCurrent evidence endorses the inclusion of MS in the algorithm for treatment of DM2 and obesity. The therapeutic approach must be multidisciplinary at experienced centers. (Source: Obesity Surgery)
Source: Obesity Surgery - June 18, 2018 Category: Surgery Source Type: research

Change in Children ’s Self-Concept, Body-Esteem, and Eating Attitudes Before and 4 Years After Maternal RYGB
ConclusionChildren ’s prevalence of overweight/obesity and eating attitudes improves soon after their mothers’ RYGB, but then return to pre-surgery levels at 4 years post-surgery, as do mothers’ sleep quality and symptoms of depression and anxiety, even though their weight loss was maintained. (Source: Obesity Surgery)
Source: Obesity Surgery - June 17, 2018 Category: Surgery Source Type: research

Metabolic Parameters, Weight Loss, and Comorbidities 4  Years After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy
ConclusionsWeight loss, reduction in medications for hypertension and diabetes, improvements in markers of diabetes and hyperlipidemia, and remission rates of hypertension were superior with RYGB vs. LSG 4  years post-operatively. Choice of bariatric procedures should be tailored to surgical risk, comorbidities, and weight loss goals. (Source: Obesity Surgery)
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Response to Letter to the Editor; Comments on “Challenges in Transition of Care for Pediatric Patients after Weight-Reduction Surgery: a Systematic Review and Recommendations for Comprehensive Care”
(Source: Obesity Surgery)
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Mid-term 4-Year Outcomes with Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy Surgery at a Single US Center
AbstractBackgroundSingle anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) is a modification of Roux-en-Y duodenal switch (RYDS). Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification.PurposeTo analyze the outcomes with SADI-S at 4  years.MethodsData from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed. All revision bariatric surgeries were excluded. Regression analyses were performed for all follow-up weight loss data...
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Influence of Biliopancreatic Diversion on Pregnancy Outcomes in Comparison to Other Bariatric Surgery Procedures
AbstractBackgroundPregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures.MethodsWe conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst whichn = 51 after biliopancreatic diversion (BPD) andn = 58 after non-malabsorptive procedures...
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Impact on Dyslipidemia After Laparoscopic Sleeve Gastrectomy
ConclusionsLSG produces an improvement in lipid profile, with a significant increase in HDL and a decrease in LDL, triglycerides, and non-HDL-C. (Source: Obesity Surgery)
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Utilization of Public System for Gastric Bands Placed by Private Providers: a 4-Year Population-Based Analysis in Ontario, Canada
AbstractLaparoscopic adjustable gastric band (LAGB) placement remains a common bariatric procedure. While LAGB procedure is performed within private clinics in most Canadian provinces, public health care is often utilized for LAGB-related reoperations. We identified 642 gastric band removal procedures performed in Ontario from 2011 to 2014 using population-level administrative data. The number of procedures performed increased annually from 101 in 2011 to 220 in 2014. Notably, 54.7% of the patients required laparotomy, and 17.6% of patients underwent a subsequent bariatric surgery. Our findings demonstrated that LAGB place...
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

The Effectiveness of Endoscopic Gastroplasty for Obesity Treatment According to FDA Thresholds: Systematic Review and Meta-Analysis Based on Randomized Controlled Trials
AbstractEndoscopic bariatric therapies (EBTs) are promising alternatives to conventional surgery for obesity. The aim of this study is to compare efficacy and safety through a systematic review and meta-analysis of the endoscopic gastroplasty techniques versus conservative treatment. We searched MEDLINE, EMBASE, Cochrane CENTRAL, Lilacs/Bireme. Randomized controlled trials (RCTs) enrolling obese patients comparing endoscopic gastroplasty to sham or diet/exercise were considered eligible. Among 6014 records, three RCTs were selected for meta-analysis. The total sample was 459 patients (312 EBTs vs 147 control). Mean total b...
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Janeway Gastrostomy for Trans-gastric ERCP: an Emergency Alternative Method to Access the Excluded Structures
(Source: Obesity Surgery)
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

Minimizing the Short-term Reoperation Rate in Abdominoplasty Procedures by Prolonged Postoperative Immobilization
ConclusionProlonged immobilization after abdominoplasty does not crucially lower the overall complication rate, but influences the severity of complications in a positive way. Increasing the duration of postoperative immobilization up to 45  h after abdominoplasty significantly decreases the reoperation rate in our practice. The risk for a surgical revision is nearly four times higher if the patient leaves bed earlier. Surgeons should consider this option especially in patients with a high risk for complication development. (Source: Obesity Surgery)
Source: Obesity Surgery - June 16, 2018 Category: Surgery Source Type: research

The Clinical Outcome of Postoperative Invasive Fungal Infections Complicating Laparoscopic Sleeve Gastrectomy
AbstractPurposePeritonitis is a major complication of bariatric surgery due to direct damage to the natural barriers to infection. Most such secondary peritoneal infections are caused by Gram-negative microorganisms; however, under certain conditions,Candida species can infect the peritoneal cavity following bariatric surgery.Materials and MethodsWe retrospectively analyzed the clinical and microbiological data of morbidly obese patients who suffered infectious complications following laparoscopic sleeve gastrectomy (LSG) at the Soroka Medical Center between January 2010 and June 2015.ResultsOut of 800 patients who underwe...
Source: Obesity Surgery - June 15, 2018 Category: Surgery Source Type: research

Initial Experience of Endoscopic Radiofrequency Waves Delivery to the Lower Esophageal Sphincter (Stretta Procedure) on Symptomatic Gastroesophageal Reflux Disease Post-Sleeve Gastrectomy
ConclusionsStretta did not improve GERD symptoms in patients post-LSG at short-term follow-up, and about 6.7% complication rate was reported. Patients were not satisfied despite the decrease in PPI dose. (Source: Obesity Surgery)
Source: Obesity Surgery - June 15, 2018 Category: Surgery Source Type: research

“Black Esophagus” and Gastric Volvulus Following Slipped Laparoscopic Adjustable Gastric Band
AbstractTo review the entity “black esophagus” and sequela of a slipped laparoscopic adjustable band. The patient’s history, physical examination, imaging, and endoscopic findings were reviewed. Detailed review of pathophysiology, presentation, diagnosis, management, and natural history was conducted. “Black esophagus,” also known as acute esophageal necrosis (AEN), is a rare condition resulting in black discoloration of the mid to distal esophagus with less than a hundred reported cases. It has not been previously documented in bariatric surgery or following laparoscopic adjustable gastric ba...
Source: Obesity Surgery - June 15, 2018 Category: Surgery Source Type: research

The Effect of Bariatric Surgery on Patients with HIV Infection: a Literature Review
AbstractObesity among human immunodeficiency virus (HIV)-infected individuals is on the rise. Bariatric procedures such as Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) alter the GI tract. Whether this alteration has any impact on the absorption of highly active antiretroviral therapy (HAART), thus affecting HIV disease markers such as CD4 cell count or viral load (VL), is not yet known. We conducted this review to look into the outcomes of bariatric surgery procedures, RYGB, SG and adjustable gastric band (AGB) and its effects on the CD4 cell counts and VL and HAART therapy. A literature search was conducted...
Source: Obesity Surgery - June 14, 2018 Category: Surgery Source Type: research

Letter to the Editor: MGB and OAGB
(Source: Obesity Surgery)
Source: Obesity Surgery - June 13, 2018 Category: Surgery Source Type: research

Comments on “Challenges in Transition of Care for Pediatric Patients after Weight-Reduction Surgery: a Systematic Review and Recommendations for Comprehensive Care”
(Source: Obesity Surgery)
Source: Obesity Surgery - June 13, 2018 Category: Surgery Source Type: research

Understanding Pathophysiological Concepts Leading to Obstructive Apnea
AbstractObstructive sleep apnea (OSA) results from a combination of several factors leading to the obstruction of the upper respiratory tract (URT). OSA represents a systemic pathophysiological entity and leads to many comorbidities such as hypertension, coronary ischemia, and stroke. Patients with this pathophysiological entity experience also an increased risk of postoperative complications. Obesity is certainly the main cause of developing OSA. However, many other predisposing factors influence the genesis of obstructive apnea. It is important to understand the complexity of the interactions between predisposing factors...
Source: Obesity Surgery - June 12, 2018 Category: Surgery Source Type: research

Endobarrier as a Pre Bariatric Surgical Intervention in High-Risk Patients: a Feasibility Study
AbstractBackgroundObesity surgery mortality risk scoring system (OS-MRS) classifies patients into high, intermediate and low risk, based on age, body mass index, sex and other comorbidities such as hypertension and history of pulmonary embolism. High-risk patients not only have a higher mortality but are more likely to develop post-operative complications necessitating intervention or prolonged hospital stay following bariatric surgery. Endoscopically placed duodenal-jejunal bypass sleeve (Endobarrier) has been designed to achieve weight loss and improve glycaemic control in morbidly obese patients with clinically proven e...
Source: Obesity Surgery - June 9, 2018 Category: Surgery Source Type: research

A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Acetaminophen on Hospital Length of Stay in Obese Individuals Undergoing Sleeve Gastrectomy
ConclusionsAcetaminophen iv may reduce hospital LoS in subjects undergoing sleeve gastrectomy. (Source: Obesity Surgery)
Source: Obesity Surgery - June 9, 2018 Category: Surgery Source Type: research

Correction to: Treatment of Obesity in Young People —a Systematic Review and Meta-analysis
In the original article, due to a production error, the text for the “Principle Findings” section was omitted as was the heading for the “Strengths and Limitations” section. The original article has been updated to correct these errors. (Source: Obesity Surgery)
Source: Obesity Surgery - June 7, 2018 Category: Surgery Source Type: research

The Impact of Obesity and Metabolic Surgery on Chronic Inflammation
AbstractBackgroundObesity and metabolic surgery is known to improve chronic inflammatory status. Whether improvement is related to anatomical changes or weight loss is still to debate.ObjectiveThe aim of this clinical trial is to compare the different bariatric procedures sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and One-anastomosis gastric bypass (OAGB), pertaining to their effects on inflammation markers.MethodsPatients who underwent SG, RYGB, or OAGB as a primary treatment for severe obesity were included. The data collected preoperatively (T0) and 1, 3, and 6 (T6)  months after surgery included gen...
Source: Obesity Surgery - June 6, 2018 Category: Surgery Source Type: research

Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery
This study aimed to investigate changes in cortical thickness following bariatric surgery. Magnetic resonance imaging (MRI) data of five patients were analyzed preoperatively and 6  months postoperatively to assess changes in global measures of cortical thickness. No patients were lost to follow-up. This study provides preliminary evidence of brain change following surgery, suggests increases in cerebral cortical thickness in patients with greater excess weight loss, and indi cates the need for further investigation using larger samples and correlation with neurocognitive measures, such as memory recall. (Source: Obesity Surgery)
Source: Obesity Surgery - June 6, 2018 Category: Surgery Source Type: research

30-Day Outcomes of Revisional Bariatric Stapling Procedures: First Report Based on MBSAQIP Data Registry
The objective of this study is to evaluate the outcomes and safety of the two most common stapling revisional procedures, namely, sleeve and gastric bypass in comparison to primary stapling procedures using the MBSAQIP data registry.MethodsWe reviewed all the sleeve and gastric bypass cases entered between January 1, 2015, and December 31, 2015, in the MBSAQIP data registry. We, then, identified sleeve and bypass patients who have had a previous bariatric procedure. Demographics and 30  day outcomes of all sleeve and gastric bypass patients were analyzed. We conducted within group comparisons comparing primary sleeve ...
Source: Obesity Surgery - June 6, 2018 Category: Surgery Source Type: research

Nationwide Macroeconomic Variables and the Growth Rate of Bariatric Surgeries in Brazil
ConclusionThere were direct relationships between the growth rate of bariatric surgeries and the evolutions of the GDP and health care expenditure per capita. These variables appear to influence the nationwide offer of bariatric surgery. (Source: Obesity Surgery)
Source: Obesity Surgery - June 6, 2018 Category: Surgery Source Type: research

Performance on the Montreal Cognitive Assessment (MoCA) in Older Adults Presenting for Bariatric Surgery
ConclusionsThe current findings suggest that cognitive impairment is common in older adults presenting for bariatric surgery. Future studies are needed to determine the most appropriate methods for detecting cognitive dysfunction in this high-risk population. (Source: Obesity Surgery)
Source: Obesity Surgery - June 5, 2018 Category: Surgery Source Type: research

Cholecalciferol Injections Are Effective in Hypovitaminosis D After Duodenal Switch: a Randomized Controlled Study
ConclusionsIn BPD/DS patients, having hypovitaminosis D despite full oral supplementation, a single injection of 600,000  IU of cholecalciferol was effective in elevating vitamin D levels and normalizing levels of intact PTH. The treatment is simple and highly effective and thus recommended, especially in cases of reduced UV-B radiation. (Source: Obesity Surgery)
Source: Obesity Surgery - June 4, 2018 Category: Surgery Source Type: research

Biography: George A. Fielding, MBBS FRACS FRCS (Eng) FRCS (Glas Hon)
(Source: Obesity Surgery)
Source: Obesity Surgery - June 4, 2018 Category: Surgery Source Type: research

Short-Term Impact of Laparoscopic Sleeve Gastrectomy on Serum Cartonectin and Vaspin Levels in Obese Subjects
ConclusionLSG-induced weight loss rapidly increases serum cartonectin level and decreases the serum vaspin level in morbidly obese subjects. The changes in cartonictin level seem to be influenced by the changes of waist circumference while the changes of HOMA-IR and LDL-C might be determinant factors of the changes in vaspin level. (Source: Obesity Surgery)
Source: Obesity Surgery - June 3, 2018 Category: Surgery Source Type: research

History and Progress of Bariatric Surgery in Malaysia
AbstractBariatric surgery has become a popular treatment modality for obesity in Malaysia. However, the absence of a standardized national registry has led to paucity of information pertaining to quantity and quality of bariatric surgery in Malaysia. In the absence of a national registry, a nationwide survey was conducted with the aim of establishing a fair estimate of case volume based on type of procedure and to identify the total number of surgeons performing those procedures at their respective centers from 1st January 2010 to 31st December 2016. For this purpose, a questionnaire was designed and distributed to bariatr...
Source: Obesity Surgery - June 3, 2018 Category: Surgery Source Type: research

Ethnicity Does Not Influence Glycemic Outcomes or Diabetes Remission After Sleeve Gastrectomy or Gastric Bypass in a Multiethnic Asian Cohort
ConclusionBaseline A1c, baseline BMI, and diabetes duration independently predict diabetes remission after MBS. GB is more effective in controlling T2D compared to SG despite similar weight loss, whereas ethnicity does not play a significant role in the multiethnic Asian cohort. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

The Association Between Weight Loss and Quality of Life 1 and 5  Years After Laparoscopic Roux-en-Y Gastric Bypass in Danish Bariatric Patients
ConclusionThis study showed that weight loss after LRYGB predicts the change in QoL of patients 1 and 5  years after surgery. Furthermore, both weight loss and change in QoL peaked after 1 year but remained significant at 5-year follow-up. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

A Dutch Nationwide Bariatric Quality Registry: DATO
This article provides a review of the aforementioned process in establishing a nationwide registry in the Netherlands.Materials and MethodsIn collaboration with the DATO ’s scientific committee and other stakeholders, an annual list of several external quality indicators was formulated. This list consists of volume, process, and outcome indicators.In addition to the annual external indicators, the database permits individual hospitals to analyze their own data. The dashboard provides several standardized reports and detailed quality indicators, which are updated on a weekly base.ResultsSince the start, all 18 Dutch b...
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

The Outcome of Bariatric Surgery in Patients Aged 75  years and Older
ConclusionOur experience suggests that bariatric surgery in selected patients aged 75  years and older would be safe and effective despite being higher risk. Age alone should not be the limiting factor for selecting patients for bariatric surgery. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

Effects of Sleeve Gastrectomy on Nonalcoholic Fatty Liver Disease in an Obese Rat Model
ConclusionsThese results suggest that the effects of SG on NAFLD should be associated with the expression of the FXR pathway in the liver in a Zucker fatty rat model. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

Correction to: Age-Related Effects of Bariatric Surgery on Early Atherosclerosis and Cardiovascular Risk Reduction
AbstractFrederik H. W. Jonker and Vera A. A. van Houten contributed equally to this work. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

Correction to: Recommendations from Two Citizens ’ Juries on the Surgical Management of Obesity
AbstractThe spelling of the name of author K. Chalkidou was incorrect in the original article. It is correct here. (Source: Obesity Surgery)
Source: Obesity Surgery - May 30, 2018 Category: Surgery Source Type: research

Revisional But Not Conversional Gastric Bypass Surgery Increases the Risk of Leaks: Review of 176 Redo out of 932 Consecutive Cases
ConclusionsCBS is safe and leads to similar early postoperative outcomes as primary RYGP whereas the indication for revisional surgery such as PR should be carefully evaluated as it is associated with an increased risk of leak. (Source: Obesity Surgery)
Source: Obesity Surgery - May 26, 2018 Category: Surgery Source Type: research

Characterization of Self-Reported Dysphagia and Impact on Weight Outcomes After Laparoscopic Sleeve Gastrectomy
ConclusionA statistically validated dysphagia-specific questionnaire was utilized to evaluate the impact of LSG on dysphagia including its functional and emotional influences. The psychosocial handicap of dysphagia significantly reduced weight loss outcomes. A correlation between PPI use and dysphagia after LSG was found. The prevalence of dysphagia after LSG and the factors that contribute to its symptoms need to be further studied. (Source: Obesity Surgery)
Source: Obesity Surgery - May 24, 2018 Category: Surgery Source Type: research

Sleeve Gastrectomy with Ligamentum Teres Cardiopexy
(Source: Obesity Surgery)
Source: Obesity Surgery - May 24, 2018 Category: Surgery Source Type: research

Treatment of Obesity in Young People —a Systematic Review and Meta-analysis
AbstractObesity in the young is increasingly prevalent. Early, effective intervention is paramount. Treatment options are lifestyle modifications, pharmacological therapies, endoscopic treatments and bariatric surgery. However, the relative effectiveness of these treatments in young patients remains unclear. We systematically identify and meta-analyse studies evaluating weight loss treatments in young people (
Source: Obesity Surgery - May 23, 2018 Category: Surgery Source Type: research

Fatal Hyperammonemic Encephalopathy in a Pediatric Patient After Roux-en-Y Gastric Bypass
(Source: Obesity Surgery)
Source: Obesity Surgery - May 23, 2018 Category: Surgery Source Type: research

An Analysis of Mid-Term Complications, Weight Loss, and Type 2 Diabetes Resolution of Stomach Intestinal Pylorus-Sparing Surgery (SIPS) Versus Roux-En-Y Gastric Bypass (RYGB) with Three-Year Follow-Up
ConclusionWith comparable weight loss and nutritional outcomes, SIPS has fewer short- and long-term complications than RYGB and better type 2 diabetes resolution rates. (Source: Obesity Surgery)
Source: Obesity Surgery - May 22, 2018 Category: Surgery Source Type: research

Duodenum Exclusion Alone Is Sufficient to Improve Glucose Metabolism in STZ-Induced Diabetes Rats
ConclusionsThus, exclusion of the duodenum alone and tube placement can effectively prevent duodenal reflux and improve glucose homeostasis, which further suggests that the duodenum plays an important role in T2DM. (Source: Obesity Surgery)
Source: Obesity Surgery - May 22, 2018 Category: Surgery Source Type: research

Evidence That the Length of Bile Loop Determines Serum Bile Acid Concentration and Glycemic Control After Bariatric Surgery
AbstractBackgroundBariatric surgery contributes to the improvement in glucose metabolism that may be related to a postoperative increase in serum bile acids (BAs). Three commonly used types of bariatric procedures, laparoscopic sleeve gastrectomy (LSG) (without creation of a bile loop), Roux-en-Y gastric bypass (RYGB), and omega-loop gastric bypass (OLGB) (with creation of shorter 100 –150 cm and longer 200–280 cm bile loops, respectively), differ in their effects on glycemic control. The aim of the study was to compare the effects of various bariatric procedures on serum BA concentration and glucose ...
Source: Obesity Surgery - May 22, 2018 Category: Surgery Source Type: research

Changes in Melatonin, Cortisol, and Body Temperature, and the Relationship Between Endogenous Melatonin Levels and Analgesia Consumption in Patients Undergoing Bariatric Surgery
AbstractBackgroundMelatonin has analgesic, anti-inflammatory, sedative, and anxiolytic properties. However, the relationship between endogenous melatonin levels and postoperative analgesic requirements has not been well elucidated in patients undergoing bariatric surgery. We studied endogenous melatonin levels, cortisol levels, body temperatures, and the relationship between the level of endogenous melatonin and postoperative morphine consumption.MethodsThe trial was conducted among 30 patients who were scheduled for laparoscopic bariatric surgery. Their ages were between 18 and 65  years and their BMIs were above 40&...
Source: Obesity Surgery - May 21, 2018 Category: Surgery Source Type: research