Manoel Passos Galvao Neto, MD
(Source: Obesity Surgery)
Source: Obesity Surgery - May 31, 2019 Category: Surgery Source Type: research

Improving Compliance with Very Low Energy Diets (VLEDs) Prior to Bariatric Surgery —a Randomised Controlled Trial of Two Formulations
ConclusionsCompliance over 2  weeks was high in both VLEDs with most subjects achieving ketosis. Overall satisfaction was moderately high, although variable. Whilst Formulite™ is a viable alternative to Optifast™, better formulations of VLED that addresses key adverse effects, whilst achieving ketosis, would be of signific ant value. (Source: Obesity Surgery)
Source: Obesity Surgery - May 21, 2019 Category: Surgery Source Type: research

The Comparative Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on 10-Year and Lifetime Atherosclerotic Cardiovascular Disease Risk
AbstractBackgroundBariatric surgery reduces atherosclerotic cardiovascular disease (ASCVD) risk. However, the comparative effect of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on 10-year and lifetime ASCVD risk, as defined by the American College of Cardiology/American Heart Association (ACC/AHA), remains unknown.MethodsUsing the ACC/AHA ASCVD risk estimator, 10-year and lifetime ASCVD risks were calculated before and 1  year after bariatric surgery for patients aged 40–78 who underwent RYGB or SG at an academic medical center in California between 2003 and 2015. Change in risk was calculated by ...
Source: Obesity Surgery - May 21, 2019 Category: Surgery Source Type: research

Dilated Gastric Pouch Resizing for Weight Loss Failure After One Anastomosis Gastric Bypass
AbstractSome patients may experience inadequate weight loss or weight regain due to gastric pouch dilation after one anastomosis gastric bypass (OAGB). Dilated gastric pouch resizing (GPR) associated with correction of eating behavior was suggested as an option in the management of these patients. Retrospective analysis of 17 consecutives patients who underwent a GPR between 2007 and 2017 was undertaken. At revision, the mean body mass index (BMI) and percentage of total weight loss (%TWL) were 41.5  ± 11 kg/m2 and 15  ± 10, respectively. Overall morbidity rate was 6.7% (n&thi...
Source: Obesity Surgery - May 21, 2019 Category: Surgery Source Type: research

Reporting Adverse Medical Device Events Is an Obligation and Not a “Fashion”
(Source: Obesity Surgery)
Source: Obesity Surgery - May 21, 2019 Category: Surgery Source Type: research

Gastroesophageal Reflux Disease After Sleeve Gastrectomy: the Need to Predict its Onset and Prevent its Consequences
(Source: Obesity Surgery)
Source: Obesity Surgery - May 21, 2019 Category: Surgery Source Type: research

Abdominal Obesity Is More Strongly Correlated with Obstructive Sleep Apnea than General Obesity in China: Results from Two Separated Observational and Longitudinal Studies
ConclusionsAbdominal obesity, rather than general obesity, appears to play a more important role in OSA. (Source: Obesity Surgery)
Source: Obesity Surgery - May 20, 2019 Category: Surgery Source Type: research

Ivor Lewis Oesophagectomy for a Distal Adenocarcinoma of the Oesophagus 10  Years After Roux-en-Y Gastric Bypass (RYGB)
(Source: Obesity Surgery)
Source: Obesity Surgery - May 20, 2019 Category: Surgery Source Type: research

Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients
ConclusionsWe were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances. (Source: Obesity Surgery)
Source: Obesity Surgery - May 19, 2019 Category: Surgery Source Type: research

Impact of Biliopancreatic Limb Length (70 cm vs 120 cm), with Constant 150 cm Alimentary Limb, on Long-Term Weight Loss, Remission of Comorbidities and Supplementation Needs After Roux-En-Y Gastric Bypass: a Prospective Randomized Clinical Trial
ConclusionA RYGB with 120  cm BPL does not achieve greater weight loss or remission of comorbidities than a RYGB with 70 cm BPL but is associated with greater deficiencies of vitamin B12, vitamin A, and folic acid.Trial RegistrationClinicalTrials.gov Identifier NCT03607305.https://clinicaltrials.gov/. (Source: Obesity Surgery)
Source: Obesity Surgery - May 19, 2019 Category: Surgery Source Type: research

Endoscopic Internal Drainage Coupled to Prompt External Drainage Mobilization Is an Effective Approach for the Treatment of Complicated Cases of Sleeve Gastrectomy
ConclusionThis study reports for the first time a well-standardized protocol of early EID after relaparoscopy coupled to rapid external drainage removal for effectively treating complicated cases of sleeve gastrectomy. Bariatric surgeons should be aware of such therapeutic strategies and include them in their arsenal against postoperative gastric staple line leaks in severely obese patients. (Source: Obesity Surgery)
Source: Obesity Surgery - May 19, 2019 Category: Surgery Source Type: research

Improving Nausea and Vomiting Post-Elipse Balloon: a Novel Single-Dose Regimen of 300  mg Netupitant/0.5 mg Palonosetron Hydrochloride
ConclusionIn our experience, the use of a single-pill netupitant/palonosetron resulted to be very easy to administer and effective in reducing vomit, nausea, and gastric pain in 87%, 70%, and 73.4% patients respectively, ameliorating the post Elipse ™ placements symptoms safely. (Source: Obesity Surgery)
Source: Obesity Surgery - May 18, 2019 Category: Surgery Source Type: research

Bowel Reconstruction to Treat Chronic Diarrhea and Hypoproteinemia Following Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy: a Single-Site Experience
ConclusionCCL is an effective way to treat symptomatic chronic diarrhea after SADI-S when conservative treatments have failed. (Source: Obesity Surgery)
Source: Obesity Surgery - May 18, 2019 Category: Surgery Source Type: research

Time to Conception after Sleeve Gastrectomy and Associated Pregnancy Outcomes —a Careful Look at the Evidence
(Source: Obesity Surgery)
Source: Obesity Surgery - May 18, 2019 Category: Surgery Source Type: research

Oral Hydration, Food Intake, and Nutritional Status Before and After Bariatric Surgery
ConclusionsCalories intake decreases after bariatric surgery, whatever the type of procedure. In addition, the prevalence of vitamin deficiency is high after bariatric surgery. Lastly, oral hydration is importantly decreased after bariatric surgery, especially after RYGBP. (Source: Obesity Surgery)
Source: Obesity Surgery - May 17, 2019 Category: Surgery Source Type: research

Effect of Bariatric Surgery on Serum Inflammatory Factors of Obese Patients: a Systematic Review and Meta-Analysis
AbstractObesity is one of the main causes of inflammation. Previous studies have reported inconclusive results regarding the effect of bariatric surgery on inflammatory markers. This systematic review and meta-analysis is aimed at describing the effect of bariatric surgery on C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor- α (TNF-α). PubMed/Medline and Scopus were systematically searched for all eligible studies from inception to June 2018. Results are expressed as weighted mean difference (MD) with 95% confidence intervals (CI) using a random effects model. Overall, 116 studies which eva...
Source: Obesity Surgery - May 16, 2019 Category: Surgery Source Type: research

Patient Recall of Education about the Risks of Alcohol Use Following Bariatric Surgery
AbstractPatients who undergo bariatric surgery are at increased risk of developing alcohol problems. The purpose of this study was to evaluate whether patients who underwent bariatric surgery recalled receiving education about alcohol prior to having surgery and to investigate their alcohol use patterns. Patients (N = 567) who underwent bariatric surgery completed a survey regarding their knowledge of risks related to post-surgical alcohol use. Although most patients recalled receiving education about abstinence from alcohol after surgery, at least one-third of patients do not appear to understand the risk s ...
Source: Obesity Surgery - May 16, 2019 Category: Surgery Source Type: research

Quantification of Liver, Subcutaneous, and Visceral Adipose Tissues by MRI Before and After Bariatric Surgery
AbstractBackgroundMorbid obesity is a worldwide epidemic and is increasingly treated by bariatric surgery. Fatty liver is a common finding; almost half of all patients with non-alcoholic steatohepatitis develop steatohepatitis. Bariatric surgery improves steatohepatitis documented by liver biopsy and single voxel magnetic resonance imaging (MRI) techniques.ObjectiveTo investigate changes before and after bariatric surgery using whole organ MRI quantification of liver, visceral, and subcutaneous fat.SettingUniversity of Basel Hospital and St. Clara Research Ltd, Basel, Switzerland.MethodsSixteen morbidly obese patients were...
Source: Obesity Surgery - May 14, 2019 Category: Surgery Source Type: research

Anemia Before and After Roux-en-Y Gastric Bypass: Prevalence and Evolution on Long-Term Follow-up
ConclusionAnemia is very frequent in severely obese patients and must be investigated both before and after bariatric surgery. The cause of anemia must be determined in order to use the best treatment available. We observed a reduction in the prevalence of chronic disease anemia during long-term follow-up probably due to the improvement in the systemic inflammatory state. (Source: Obesity Surgery)
Source: Obesity Surgery - May 14, 2019 Category: Surgery Source Type: research

Type 2 Diabetes Mellitus and Preoperative HbA1c Level Have no Consequence on Outcomes after Laparoscopic Sleeve Gastrectomy —a Cohort Study
AbstractIntroductionAvailable clinical data on the influence of baseline HbA1c postoperative morbidity and readmission after laparoscopic sleeve gastrectomy is scarce. This prompted us to conduct a multicenter retrospective study evaluating the influence of chronic hyperglycemia on postoperative course among patients undergoing laparoscopic sleeve gastrectomy (SG). We aimed to investigate the influence of baseline HbA1c levels on postoperative outcomes in patients after SG.Material and MethodsWe conducted a multicenter retrospective cohort study of consecutive patients who underwent SG from March 2017 to March 2018 in seve...
Source: Obesity Surgery - May 14, 2019 Category: Surgery Source Type: research

Variability of Length of Small Intestine in Indian Population and Its Correlation with Type 2 Diabetes Mellitus and Obesity
ConclusionSmall intestinal length had significant but a weak positive correlation in patients who had HbA1c ≥ 6.5% and RBS levels ≥ 200 mg/dL. (Source: Obesity Surgery)
Source: Obesity Surgery - May 14, 2019 Category: Surgery Source Type: research

From the Editor ’s Desk
(Source: Obesity Surgery)
Source: Obesity Surgery - May 13, 2019 Category: Surgery Source Type: research

Roux-en-Y Gastric Bypass Improves Metabolic Conditions in Association with Increased Serum Bile Acids Level and Hepatic Farnesoid X Receptor Expression in a T2DM Rat Model
ConclusionsRYGB ameliorates glucose and lipid metabolism accompanied by weight loss and calorie restriction. The liver exhibited a marked improvement in lipid accumulation after RYGB. The bile acids level, FXR, and its target transcriptional factor SHP expression were elevated. Meanwhile, our study demonstrated that the increased bile acids-FXR signaling, followed by the reduced hepatic gluconeogenesis, lipogenesis, and increased fatty acidβ oxidation may contribute to improved metabolic conditions after RYGB. (Source: Obesity Surgery)
Source: Obesity Surgery - May 12, 2019 Category: Surgery Source Type: research

Endoscopy Before Laparoscopic Sleeve Gastrectomy
(Source: Obesity Surgery)
Source: Obesity Surgery - May 12, 2019 Category: Surgery Source Type: research

Improvement in Food Intolerance Resulting from Roux-En-Y Gastric Bypass after Speech Therapy Intervention in Chewing
AbstractIntroductionFood intolerance is expected during the postoperative period following gastric bypass and may be associated with inadequate chewing.ObjectiveTo evaluate chewing before and after speech therapy intervention in subjects undergoing Roux-en-Y gastric bypass who present with food intolerance.Materials and MethodsThis was a randomized controlled trial, approved by the Brazilian Ethics and Research Committee under n. 438,600. The study population was allocated into two groups: the study group (SG), who received speech therapy intervention, and the control group (CG), who did not receive any intervention, in si...
Source: Obesity Surgery - May 11, 2019 Category: Surgery Source Type: research

Measurement of Liver Stiffness with 2D-Shear Wave Elastography (2D-SWE) in Bariatric Surgery Candidates Reveals Acceptable Diagnostic Yield Compared to Liver Biopsy
ConclusionTwo-dimensional shear wave elastography of the liver can be feasible and has good accuracy in severely obese candidates for bariatric surgery. Therefore, 2D-SWE may be a good option for assessing liver fibrosis, especially in the early stages of fibrosis to lessen complications of surgery in this population. However, this method should be applied on a larger scale for late stage of fibrosis. (Source: Obesity Surgery)
Source: Obesity Surgery - May 10, 2019 Category: Surgery Source Type: research

Changes in Cardiorespiratory Fitness After Gastric Bypass: Relations with Accelerometry-Assessed Physical Activity
This study aimed to objectively quantify changes in CRF and habitual physical activity 6  months after bariatric surgery and to examine whether change in CRF was related to change in physical activity.MethodsSecondary analyses were performed on data from women who underwent Roux-en-Y gastric bypass (RYGB) between 2010 and 2014. Measurements were performed before and 6  months after RYGB and included V̇O2peak (graded maximal exercise test on a cycle ergometer), habitual physical activity (Actigraph GT3x accelerometer worn during 7  days), and body composition (DXA absorptiometry). Changes after RYGB were ana...
Source: Obesity Surgery - May 9, 2019 Category: Surgery Source Type: research

Reliability and Educational Value of Laparoscopic Sleeve Gastrectomy Surgery Videos on YouTube
ConclusionImportance of online media in the education of surgery cannot be overestimated. However, trainees are advised to search for peer-reviewed contents dedicated to education. (Source: Obesity Surgery)
Source: Obesity Surgery - May 9, 2019 Category: Surgery Source Type: research

Anatomical Relations Between the Esogastric Junction, the Diaphragm, the Pleura, and the Left Lung in Chronic Esogastro-bronchial and/or Esogastro-pleural Fistulas After Sleeve Gastrectomy
ConclusionsEsogastro-bronchial and gastro-pleural fistulas after SG originated mostly at the top of the staple line. Eso-bronchial fistulas had a trans-hiatal passage with a proximal bronchial termination, while gastro-bronchial fistulas had a trans-diaphragmatic passage with a distal bronchial termination. (Source: Obesity Surgery)
Source: Obesity Surgery - May 8, 2019 Category: Surgery Source Type: research

Serum Bile Acid Levels Before and After Sleeve Gastrectomy and Their Correlation with Obesity-Related Comorbidities
ConclusionsSerum BA are associated with glucose metabolism and particularly with markers of insulin-resistance. SG modifies circulating BA pool size and composition. SG-induced BA changes are associated with insulin-resistance amelioration. In conclusion, an interplay between glucose metabolism and circulating BA exists but further studies are needed. (Source: Obesity Surgery)
Source: Obesity Surgery - May 8, 2019 Category: Surgery Source Type: research

Bone Turnover Markers After Standard and Distal Roux-en-Y Gastric Bypass: Results from a Randomized Controlled Trial
AbstractBackgroundRoux-en-Y gastric bypass is associated with increased risk of bone fractures. Malabsorptive procedures may be associated with secondary hyperparathyroidism and detrimental effects on bone health. We aimed to compare the effects of standard and distal gastric bypass on bone turnover markers 2  years after surgery.MethodsPatients with body mass index (BMI) 50 –60 kg/m2 (n = 113) were randomized to standard or distal gastric bypass, 105 patients (95%) completed 2-year follow-up. Serum C-terminal telopeptide of type I collagen (CTX-1), procollagen type I N-propeptide (PINP), and ...
Source: Obesity Surgery - May 8, 2019 Category: Surgery Source Type: research

Effects of Bariatric Surgery in Male Obesity-Associated Hypogonadism
AbstractIntroductionThe prevalence of obesity has grown exponentially over the last several decades. Research has linked male obesity to changes in the gonadal axis, which can induce functional hypogonadism. Bariatric surgery provides sustained weight loss and metabolic improvement. This was a retrospective cohort study to evaluate the male gonadal axis and metabolic profiles of obese individuals during the bariatric pre- and post-operative periods while comparing them to a normal body mass index (BMI) group.MethodsTwenty-nine obese men, who underwent bariatric surgery between 2012 and 2016 at the Federal University of San...
Source: Obesity Surgery - May 7, 2019 Category: Surgery Source Type: research

Biography: Tarek Mahdy
(Source: Obesity Surgery)
Source: Obesity Surgery - May 7, 2019 Category: Surgery Source Type: research

Management of Staple Line Leaks Following Sleeve Gastrectomy —a Systematic Review
ConclusionPrompt identification and adequate source control are crucial to successfully manage a staple line leak following sleeve gastrectomy. Treatment options are influenced by the clinical status of the patient. A stepwise treatment escalation approach is required to improve outcomes. (Source: Obesity Surgery)
Source: Obesity Surgery - May 6, 2019 Category: Surgery Source Type: research

Sleeve Gastrectomy, GERD, and Barrett ’s Esophagus: It Is Time for Objective Testing
(Source: Obesity Surgery)
Source: Obesity Surgery - May 6, 2019 Category: Surgery Source Type: research

Secured Lumen-Apposing Fully Covered Metallic Stents for Stenoses in Post-Bariatric Surgery Patients
AbstractNew approaches for refractory stenosis in post-bariatric surgical patients include fully covered lumen-apposing metallic stents (LAMS); however, stent migration continues to be a problem. Endoscopic suture placement to LAMS can reduce the migration. Aiming to assess the feasibility and safety of the procedure, we evaluated nine consecutive patients with inability to tolerate a solid diet due to a benign gastrointestinal stricture recalcitrant to previous attempts at endoscopic therapy. All patients were symptom-free starting from 1-week follow-up. Median stent dwell time was nearly 3  months. During the remova...
Source: Obesity Surgery - May 4, 2019 Category: Surgery Source Type: research

A Case Report of Myotonic Disease and Gastric Bypass and a Literature Review
We report the case of a woman with myotonic dystrophy type 1, followed for 8  years after a Roux-en-Y gastric bypass. Weigh loss was substantial (53% of initial body weight) with functional improvement in spite of the natural course of the pathology. Five other cases have been published and have reported a relatively positive benefit/risk ratio. Precautions are to be taken at the time of anesthesia and follow-up in order to detect possible degradation of muscle function. (Source: Obesity Surgery)
Source: Obesity Surgery - May 3, 2019 Category: Surgery Source Type: research

Reply to Letter Regarding “Sleeve Gastrectomy, GERD and Barrett’s Esophagus: It is time for objective testing”
(Source: Obesity Surgery)
Source: Obesity Surgery - May 3, 2019 Category: Surgery Source Type: research

Employment Outcomes 2  Years After Bariatric Surgery: Relationship to Quality of Life and Psychosocial Predictors
AbstractObjectivesBariatric surgery is the most effective long-term treatment for severe obesity. In addition to sustained weight loss, bariatric surgery can result in improvements in mental and physical health-related quality of life (HRQOL) and, consequently, work capacity. The purpose of our study was to evaluate changes to employment impairment (EI) and related HRQOL in patients 2  years post-bariatric surgery.MethodsProspective data was collected on a cohort of 211 patients who underwent bariatric surgery. The Lam Employment Absence and Productivity Scale (LEAPS) and the 36-Item Short Form Survey (SF-36) were use...
Source: Obesity Surgery - May 3, 2019 Category: Surgery Source Type: research

A 5-Year Follow-up in Children and Adolescents Undergoing One-Anastomosis Gastric Bypass (OAGB) at a European IFSO Excellence Center (EAC-BS)
ConclusionsOAGB is a valid alternative for long-term weight loss and remission of comorbidities in childhood and adolescence. No cases of malnutrition or growth disorders were observed. (Source: Obesity Surgery)
Source: Obesity Surgery - May 2, 2019 Category: Surgery Source Type: research

Trending Weight Loss Patterns in Obese and Super Obese Adolescents: Does Laparoscopic Sleeve Gastrectomy Provide Equivalent Outcomes in both Groups?
AbstractBackgroundMany factors, including preoperative weight, may determine final weight loss after bariatric surgery; however, their proportional contribution is unclear. To such end, we evaluated weight loss patterns among obese adolescents.MethodsWe evaluated 57 adolescents who underwent laparoscopic sleeve gastrectomy from 2011 to 2017. Data collection included demographics, anthropometrics, and comorbidities and was done over a 3-year follow-up period. Statistical analysis was performed using Student ’st test and repeated measures ANOVA.ResultsIn the morbidly obese (MO) group, 82% were female, while 52% were ma...
Source: Obesity Surgery - May 2, 2019 Category: Surgery Source Type: research

A Late Onset of Wernicke-Korsakoff Encephalopathy After Biliopancreatic Diversion: a Case Report
(Source: Obesity Surgery)
Source: Obesity Surgery - May 1, 2019 Category: Surgery Source Type: research

A Pilot, Randomized Study in Women of Nutrition-Related Clinical Chemistry at 6  Weeks after Roux en Y Gastric Bypass: Comparison of Two Nutrition Support Plans
ConclusionsNutrition-related parameters showed varying trends 6  weeks after RNYGB. Some of the trends were affected by the type of nutritional support provided. (Source: Obesity Surgery)
Source: Obesity Surgery - April 30, 2019 Category: Surgery Source Type: research

Comparative Efficacy of Bariatric Surgery in the Treatment of Morbid Obesity and Diabetes Mellitus: a Systematic Review and Network Meta-Analysis
ConclusionsRYGB and SG had excellent long-term outcomes for both the %EWL and DM remission rates. Additionally, SG had a relatively lower risk of adverse events than RYGB. (Source: Obesity Surgery)
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

Impact of Intragastric Balloon Treatment on Adipokines, Cytokines, and Metabolic Profile in Obese Individuals
AbstractBackgroundObesity is accompanied by adipose tissue remodeling characterized by increased production of tumor necrosis factor-alpha (TNF- α), interleukin (IL)-6, leptin and resistin and reduced secretion of adiponectin, which favors inflammation, metabolic disorders, and cardiovascular diseases. Although intragastric balloon (IGB) can be considered safe and effective for weight loss, its effect on serum levels of these biomarkers has been evaluated only in a few studies, while no previous study evaluated its effect on circulating levels of resistin, TNF-α, and IL-6. The aim of this study was to evaluate ...
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

Dynamic Adaptive Changes of the Ileum Transposed to the Proximal Small Intestine in Rats
ConclusionsThe transposed distal ileum underwent dynamic adaptation processes that may help explain the metabolic changes after RYGB. (Source: Obesity Surgery)
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

IFSO-APC 2019 Abstracts
(Source: Obesity Surgery)
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

Simulation of Appointment Scheduling Policies: a Study in a Bariatric Clinic
ConclusionIICR was successfully implemented, and the practical results were very close to the simulated ones. (Source: Obesity Surgery)
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

Correction to: Longitudinal Impacts of Gastric Bypass Surgery on Pharmacodynamics and Pharmacokinetics of Statins
In the original article the authors failed to include the following footnote: (Source: Obesity Surgery)
Source: Obesity Surgery - April 29, 2019 Category: Surgery Source Type: research

A Clinical Decision Support System for Predicting the Early Complications of One-Anastomosis Gastric Bypass Surgery
ConclusionsUsing the CDSS designed, we could accurately predict the early complications of OAGB surgery. (Source: Obesity Surgery)
Source: Obesity Surgery - April 26, 2019 Category: Surgery Source Type: research