Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study

Conclusion This study supports the notion that exercise programs with a focus on gross motor skills development could result in elevated BDNF concentrations in healthy older adults. Furthermore, improvements in cognitive performances could be observed without significant concomitant increases in BDNF levels. Ethics Statement This study was approved and carried out in accordance with the recommendations of the ethics guidelines of the Comité d’éthique de la recherche vieillissement-neuroimagerie du CIUSSS du Centre-Sud-de-l’île-de-Montréal with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. Author Contributions NB, LBo, and LBh conceived and designed the experiments. NB, FSt-O, and TV performed the tests. C-AG, NB, FSt-O, and NA analyzed the data. C-AG, NB, and LBh wrote the manuscript. All authors revised and contributed to the manuscript for important intellectual content. Funding This study was supported by a grant from the Canadian Institutes of Health Research. NA holds a New Investigator Salary Award from the Canadian Institutes of Health Research. NB was supported by a doctoral scholarship offered by the Quebec Network for Research on Aging. LBh was supported by the Canadian Research Chair program. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relation...
Source: Frontiers in Physiology - Category: Physiology Source Type: research