Exceptional longevity: why some people live to be more than 100-year old

Interventions that promote longevity, remembered by mnemonic:DEEP purple - “eat colorful plant foods:Dietary modification,Exercise, activeEngagement,Purposeful living (click here toenlarge the image).Based on a Mayo Clinic Proceedings article (https://www.mayoclinicproceedings.org/article/S0025-6196(18)30792-4/):Exceptional Human Longevity: the oldest old have an extreme phenotype of delayed onset of age-related diseases and/or resistance to lethal illnesses occurring earlier in life.Centenarians have delayed onset of chronic diseasesDuring the span of human history the likelihood of living from birth to age 100 rose from 1 in 20 million to 1 in 50 as of year 1995 (for females in low-mortality nations such as Japan and Sweden). By 2009, this probability increased to 1 in 2. About 1 in 5,000 persons in the United States is a centenarian or older. Human longevity now exceeds 115 years. However, maximum life span has remained largely unchanged. There is a limit to human longevity, and it may be around 120 years.In centenarians, theage at onset of common age-associated diseases is delayed: 43% of both male and female centenarians reach the age of 80 years before experiencing age-associated illness.There is anabsence of any disease diagnosis in some 15% and 30% of female and male centenarians, respectively, at the age of 100 years!As many as 25% of centenarians are cognitively intact.Geographic ClustersGeographic Clustering of Exceptionally Long-Lived Individuals: Countries with...
Source: Clinical Cases and Images - Blog - Category: Universities & Medical Training Tags: Lifestyle Longevity Mayo Clinic Source Type: blogs