The Nutri-Score nutrition label: Associations between the underlying nutritional profile of foods and lipoprotein particle subclass profiles in adults
CONCLUSIONS: A higher FSAm-NPS score is associated with a less favourable lipoprotein particle subclass profile in middle-to older-aged adults which may be a potential mechanism underlying reported health benefits of a healthy diet according to Nutri-Score rating.PMID:38692976 | DOI:10.1016/j.atherosclerosis.2024.117559 (Source: Atherosclerosis)
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Se án R Millar Pilar Navarro Janas M Harrington Ivan J Perry Catherine M Phillips Source Type: research
Angiopoietin-2, vascular endothelial growth factor family, and heparin binding endothelial growth factor are associated with subclinical atherosclerosis in rheumatoid arthritis
CONCLUSIONS: The selected GFs were closely related to atherosclerosis in patients with RA and are potential predictors of CV disease in patients with RA.PMID:38689721 | PMC:PMC11059138 | DOI:10.1016/j.csbj.2024.04.042 (Source: Atherosclerosis)
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Anna P àmies D ídac Llop Daiana Ibarretxe Roser Rosales Luis Masana Joan-Carles Vallv é Silvia Paredes Source Type: research
Association of healthy diet score and adiposity with risk of colorectal cancer: findings from the UK Biobank prospective cohort study
CONCLUSION: Adiposity-mediated effects were limited in the link between dietary patterns and CRC incidence, implying that solely addressing adiposity may not sufficiently reduce CRC risk. Interventions, such as improving dietary quality in people with adiposity or promoting weight control in those with unhealthy eating habits, may provide an effective strategy to reduce CRC risk.PMID:38693451 | DOI:10.1007/s00394-024-03418-7 (Source: Cancer Control)
Source: Cancer Control - May 1, 2024 Category: Cancer & Oncology Authors: Jiasheng Huang Enlin Ye Xiaolin Li Dongdong Niu Jia Wang Yumei Zhao Yiling Hu Suru Yue Xuefei Hou Zhe Huang Jiayuan Wu Source Type: research
Concomitant human papillomavirus (HPV) vaccination and screening for elimination of HPV and cervical cancer
In conclusion, concomitant HPV vaccination and HPV screening appears to be a realistic option for faster cervical cancer elimination. Clinicaltrials.gov identifier: NCT04910802; EudraCT number: 2020-001169-34.PMID:38693149 | DOI:10.1038/s41467-024-47909-x (Source: Cancer Control)
Source: Cancer Control - May 1, 2024 Category: Cancer & Oncology Authors: Laila Sara Arroyo M ühr Andrea Gini Emel Yilmaz Sadaf S Hassan Camilla Lagheden Emilie Hultin Ainhoa Garcia Serrano Agustin E Ure Helena Andersson Roxana Merino K Miriam Elfstr öm Iacopo Baussano Joakim Dillner Source Type: research
Safety and immunogenicity of a polyvalent DNA-protein HIV vaccine with matched Env immunogens delivered as a prime-boost regimen or coadministered in HIV-uninfected adults in the USA (HVTN 124): a phase 1, placebo-controlled, double-blind randomised controlled trial
Lancet HIV. 2024 May;11(5):e285-e299. doi: 10.1016/S2352-3018(24)00036-5.ABSTRACTBACKGROUND: An effective HIV vaccine will most likely need to have potent immunogenicity and broad cross-subtype coverage. The aim of the HIV Vaccine Trials Network (HVTN) 124 was to evaluate safety and immunogenicity of a unique polyvalent DNA-protein HIV vaccine with matching envelope (Env) immunogens.METHODS: HVTN 124 was a randomised, phase 1, placebo-controlled, double-blind study, including participants who were HIV seronegative and aged 18-50 years at low risk for infection. The DNA vaccine comprised five plasmids: four copies expressin...
Source: Cancer Control - May 1, 2024 Category: Cancer & Oncology Authors: Ian Frank Shuying S Li Nicole Grunenberg Edgar T Overton Samuel T Robinson Hua Zheng Kelly E Seaton Jack R Heptinstall Mary A Allen Kenneth H Mayer Daniel A Culver Michael C Keefer Sri Edupuganti Michael N Pensiero Vijay L Mehra Stephen C De Rosa Daryl E Source Type: research
Bichectomy Surgery and EMG Masticatory Muscles Function in Adult Women: A Longitudinal Study
CONCLUSION: Bichectomy surgery did not modify the electromyographic activity of the masseter and temporal muscles during the rest task but may have influenced variations in the electromyographic signal during different mandibular tasks after 60 days of surgery, suggesting compensatory adaptations and functional recovery.CLINICAL SIGNIFICANCE: Understanding the impact of buccal fat removal surgery on the stomatognathic system function provides insights into postoperative functional recovery and potential compensatory adaptations, guiding clinical management and rehabilitation strategies for patients undergoing such procedur...
Source: J Contemp Dent Pract - May 1, 2024 Category: Dentistry Authors: Alice Helena de L Santos Cardoso Marcelo Palinkas Nicole B Bettiol Patr ícia S de Lima Paulo B de Vasconcelos Samuel P Xavier Gabriella Sg Silva Thamyres Branco Isabela H Regalo Selma Siessere Simone Ch Regalo Source Type: research
The Correlates of Collective and Individual Trauma on Mental Health Outcomes Among Afghan Refugees: A Study of Sociodemographic Differences
This study sought to explore the relationship between collective trauma and mental health outcomes within the Afghan refugee population in the United States, paying particular attention to the influence of sociodemographic factors. Identifying subgroups at greater risk allows for the development of more targeted mental health interventions. The study surveyed 173 Afghan refugees employing snowball sampling, utilizing a cross-sectional design. Data collection was facilitated through online and in-person surveys in English, Dari, and Pashto. Key measures included the Harvard Trauma Questionnaire for individual trauma experie...
Source: Community Mental Health Journal - May 1, 2024 Category: Psychiatry Authors: Jaclyn Kirsch Arati Maleku Youn Kyoung Kim Taqdeerullah Aziz Shaima Dada Hanna Haran Katherine Kitchens Source Type: research
Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults
CONCLUSIONS: The MMSE and MoCA screening tools effectively identified gray and white matter brain damage in older adults with varying degrees of cognitive impairment. Lower MMSE scores are associated with MTL atrophy and lesions, and lower MoCA scores are related to PWM lesions. The concurrent use of MMSE and MoCA is recommended for assessing structural changes in distinct brain regions.PMID:38690079 | PMC:PMC11060871 | DOI:10.1155/2024/5527225 (Source: Journal of Aging Research)
Source: Journal of Aging Research - May 1, 2024 Category: Geriatrics Authors: Paula Andreatta Maduro Manoel Pereira Guimar ães Mateus de Sousa Rodrigues Ana Paula Pereira Rolim Coimbra Pinto Am érico Alves da Mota Junior Alaine Souza Lima Rocha Juliana Magalh ães Duarte Matoso Bruno Bavaresco Gambassi Paulo Adriano Schwingel Source Type: research
"Health challenges and midwifery support for new mothers after childbirth: A cross-sectional study in Sweden"
CONCLUSION AND IMPLICATION FOR PRACTICE: It is notable that 16 % of new mothers seek emergency care in the first weeks after childbirth. This study has practical implications for midwifery practice and policy. There is a need for tailored postnatal support strategies so that midwives potentially are able to mitigate emergency department visits. Further studies should look at whether the high number of emergency visits among new mothers varies throughout Sweden, and whether this may be a result of reduced time of hospital stay after childbirth or other factors.PMID:38692249 | DOI:10.1016/j.midw.2024.104020 (Source: Midwifery)
Source: Midwifery - May 1, 2024 Category: Midwifery Authors: Ragnhild Eikemo Mia Barimani Viola Nyman Wibke Jonas Anna Vikstr öm Source Type: research
pDNA-tachyplesin treatment stimulates the immune system and increases the probability of apoptosis in MC4-L2 tumor cells
Amino Acids. 2024 May 1;56(1):34. doi: 10.1007/s00726-024-03393-7.ABSTRACTBreast cancer is the most common cancer among women worldwide, and marine creatures are the most abundant reservoir of anticancer medicines. Tachyplesin peptides have shown antibacterial capabilities, but their potential to inhibit cancer growth and trigger cancer cell death has not been investigated. A synthetic tachyplesin nucleotide sequence was generated and inserted into the pcDNA3.1( +) Mammalian Expression Vector. PCR analysis and enzyme digesting procedures were used to evaluate the vectors' accuracy. The transfection efficiency of MCF-7 and ...
Source: Amino Acids - May 1, 2024 Category: Biochemistry Authors: Fatemeh Mahmoudi-Filabadi Abbas Doosti Source Type: research
Mortality, bone density and grip strength: lessons from the past and hope for the future?
CONCLUSION: We report strong relationships between grip strength and mortality compared with BMD. We hypothesize that this may reflect better recognition and treatment of low BMD in this cohort.PMID:38690291 | PMC:PMC11057971 | DOI:10.1093/rap/rkae046 (Source: Adv Data)
Source: Adv Data - May 1, 2024 Category: Epidemiology Authors: Leo D Westbury Faidra Laskou Harnish P Patel Cyrus Cooper Elaine M Dennison Source Type: research
Expression and clinical significance of short-chain fatty acids in patients with intrahepatic cholestasis of pregnancy
CONCLUSION: Compared with the NP group, significant alterations were observed in the SCFAs of maternal serum and cord blood in the ICP group, although they displayed distinct patterns of change. Furthermore, the SCFA levels in maternal serum and cord blood were significantly positively correlated. Notably, certain maternal serum SCFAs, specifically caproic and acetic acids, demonstrated excellent diagnostic efficiency for ICP.PMID:38689740 | PMC:PMC11056904 | DOI:10.4254/wjh.v16.i4.601 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - May 1, 2024 Category: Gastroenterology Authors: Shuai-Jun Ren Jia-Ting Feng Ting Xiang Cai-Lian Liao Yu-Ping Zhou Rong-Rong Xuan Source Type: research
Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production
ConclusionsThese results suggest that liveS. salivarius or its cell-free supernatant significantly ameliorated the disruption of epithelial tight junctions induced byP. melaninogenica, likely through the inhibition ofP. melaninogenica growth mediated by metabolic acid production. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 1, 2024 Category: Microbiology Authors: Pingyi Zhu,
Ruru Shao,
Pan Xu,
Ruowen Zhao,
Chen Zhao,
Jian Fei,
Yuan He Tags: ORIGINAL ARTICLE Source Type: research
Research in brief: How prevalent is rough sex? Results from a national online sample of adults in Germany
DiscussionResults show that rough sex is common. Sexual health professionals, educators, and researchers should be prepared to guide current and aspiring practitioners of rough sex, helping them understand potential benefits, risks, and age- and gender-related differences. (Source: Perspectives on Sexual and Reproductive Health)
Source: Perspectives on Sexual and Reproductive Health - May 1, 2024 Category: Sexual Medicine Authors: Nicola D öring,
M. Rohangis Mohseni,
Laura Pietras,
Arne Dekker,
Peer Briken Tags: RESEARCH IN BRIEF Source Type: research
Evaluating the development of endometriosis and adenomyosis lesions over time: An ultrasound study of symptomatic women
ConclusionsOur findings suggest that in symptomatic women, endometriosis and adenomyosis lesions visible at ultrasound may develop over time. However, majority of women remain having normal ultrasound examinations despite symptoms. Exacerbation of dysmenorrhea or chronic pelvic pain during follow-up was not associated with the development of endometriosis or adenomyosis lesions visible at ultrasound, suggesting that even women with less severe symptoms might benefit from a follow-up ultrasound when indicated. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 1, 2024 Category: OBGYN Authors: Sofie Orlov,
Povilas Sladkevicius,
Ligita Jokubkiene Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
