The long non-coding RPPH1 is decreased in leukocytes and increased in plasma from women developing pre-eclampsia
In conclusion, RPPH1 expression in leukocytes was significantly decreased in women with pre-eclampsia, and the expression at 22-24 weeks associated with the subsequent development of pre-eclampsia. RPPH1 in leukocytes may be a useful biomarker for prediction and/or early detection of pre-eclampsia and an unknown regulator of the signaling affecting immune cells.PMID:38685609 | DOI:10.1093/biolre/ioae069 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 30, 2024 Category: Reproduction Medicine Authors: Dina-Marie Munkelien Myhrer Monica Fr øystad Marie Cecilie Paasche Roland Thor Ueland Tove Lekva Source Type: research
Associations between short-term exposure to air pollution and thyroid function in a representative sample of the Korean population
CONCLUSIONS: As the subtle changes in thyroid function can affect various organ systems, the present results may have substantial public health implications despite the relatively modest effect sizes. Because this was a cross-sectional study, it is necessary to conduct further experimental or repeated-measures studies to consolidate the current results.PMID:38685294 | DOI:10.1016/j.envres.2024.119018 (Source: Environmental Research)
Source: Environmental Research - April 30, 2024 Category: Environmental Health Authors: Kyoung-Nam Kim SoHyun Park Junseo Choi Il-Ung Hwang Source Type: research
The Diagnosis, Treatment, and Prevention of Recurrent Urinary Tract Infection
CONCLUSION: rUTI poses a challenge for the treating physician. The measures to be taken must be considered on an individual basis. Vulnerable groups, such as older patients, need special attention.PMID:38686602 | DOI:10.3238/arztebl.m2024.0068 (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 30, 2024 Category: General Medicine Authors: Guido Schmiemann Jennifer Kranz Falitsa Mandraka S ören Schubert Florian Wagenlehner Ildik ó Gágyor Source Type: research
Evaluation of the Efficacy and Safety of Tenofovir Disoproxil Fumarate in Intercepting Mother-to-Child Transmission of Hepatitis B Virus
This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment. Clinical and laboratory data of infants were assayed at delivery and 7-months post-partum visit and compared between the two groups. There was no difference in clinical characteristics of participants between the two groups. Ther...
Source: Acta Medica Okayama - April 30, 2024 Category: General Medicine Authors: Dongxiang Han Jianxiu Du Wei Wang Cui Wang Source Type: research
The long non-coding RPPH1 is decreased in leukocytes and increased in plasma from women developing pre-eclampsia
In conclusion, RPPH1 expression in leukocytes was significantly decreased in women with pre-eclampsia, and the expression at 22-24 weeks associated with the subsequent development of pre-eclampsia. RPPH1 in leukocytes may be a useful biomarker for prediction and/or early detection of pre-eclampsia and an unknown regulator of the signaling affecting immune cells.PMID:38685609 | DOI:10.1093/biolre/ioae069 (Source: Reproductive Biology)
Source: Reproductive Biology - April 30, 2024 Category: Reproduction Medicine Authors: Dina-Marie Munkelien Myhrer Monica Fr øystad Marie Cecilie Paasche Roland Thor Ueland Tove Lekva Source Type: research
Seroprevalence of Toxoplasma gondii and Associated Risk Factors among Pregnant Women in Algeria
Am J Trop Med Hyg. 2024 Apr 30:tpmd230187. doi: 10.4269/ajtmh.23-0187. Online ahead of print.ABSTRACTToxoplasma gondii is an obligate intracellular protozoan parasite affecting all warm-blooded vertebrates, including humans. Infections in humans can lead to severe clinical manifestations in pregnant women and immunocompromised patients. The aim of the present study was to assess seroprevalence of T. gondii infection and to identify the associated risk factors among pregnant women from southern Algeria. A cross-sectional study was conducted from March 2021 to May 2022 among 1,345 pregnant women. A structured questionnaire w...
Source: Am J Trop Med Hyg - April 30, 2024 Category: Infectious Diseases Authors: Soumia Sebaa Jerzy M Behnke Amina Labed Marawan A Abu-Madi Source Type: research
Zibotentan Can Be Co-administered with Contraceptives Containing Ethinyl Estradiol and Levonorgestrel: A Pharmacokinetic Drug-Drug Interaction Study
In conclusion, contraception containing ethinyl estradiol/levonorgestrel is regarded possible under zibotentan-containing treatments. This expands choices for women of childbearing potential, supporting diversity in the ZENITH High Proteinuria trial.PMID:38686600 | DOI:10.1002/cpt.3280 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - April 30, 2024 Category: Drugs & Pharmacology Authors: Anne-Kristina Mercier Abigail K Kois Deeyen Karsanji Richard Baldry Filip Birve Maria Hedwall Oleksandr Molodetskyi Michael Gillen Source Type: research
Basal Hyperglycemia Contributes More Than Fifty Percent to Time in Range in Pregnant Women with Type 1 Diabetes
CONCLUSIONS: Basal hyperglycemia was the major contributor to TIR during pregnancy. Along with controlling the postprandial hyperglycemia, pregnant women with T1DM who did not reach the target of TIR may benefit more from the optimization of insulin regimens focusing on reducing basal glucose.PMID:38686666 | DOI:10.1210/clinem/dgae291 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 30, 2024 Category: Endocrinology Authors: Ping Ling Daizhi Yang Chaofan Wang Xueying Zheng Sihui Luo Xubin Yang Hongrong Deng Wen Xu Jinhua Yan Jianping Weng Source Type: research
Psychometric Evaluation of the Family Willingness for Caregiving Scale
CONCLUSIONS: Further testing of the FWCS is needed. After refinement, the FWCS could be used to evaluate factors contributing to caregiving willingness of family members of ICU patients and advance the science related to family engagement in the ICU. Additionally, it could be used as a practical tool to suggest family caregiving activities in the ICU.PMID:38688853 | DOI:10.4037/ajcc2024809 (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - April 30, 2024 Category: Nursing Authors: Cindy Wilk Amy Petrinec Source Type: research
Age group-specific changes in keratinocyte cancer treatment rates in Australia, 2012- 2021: a retrospective cohort study based on MBS claims data
CONCLUSIONS: Rates of MBS-subsidised treatment for keratinocyte cancers increased during 2012-2019, but BCC/SCC treatment rates declined among younger Australians, who have probably been exposed to less sunlight than earlier generations because of public health interventions and population-wide lifestyle changes related to technology use.PMID:38685827 | DOI:10.5694/mja2.52293 (Source: Med J Aust)
Source: Med J Aust - April 30, 2024 Category: General Medicine Authors: Catherine M Olsen Nirmala Pandeya Rachel E Neale David C Whiteman Source Type: research
Burden and outcomes of postpartum haemorrhage in Nigerian referral-level hospitals
CONCLUSIONS: A PPH prevalence of 3.2% can be reduced with improved access to skilled birth attendants.PMID:38686455 | DOI:10.1111/1471-0528.17822 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Tajudeen Adebayo Ayodeji Adefemi Idowu Adewumi Opeyemi Akinajo Bola Akinkunmi David Awonuga Olufemi Aworinde Ekundayo Ayegbusi Iyabode Dedeke Iretiola Fajolu Zainab Imam Olusoji Jagun Olumide Kuku Ezra Ogundare Timothy Oluwasola Lawal Oyeneyin Damilola Ad Source Type: research
Factors associated with caregiver burden in primary caregivers of older adults with type2 diabetes
CONCLUSIONS: Prevention programs are required to avoid CC and complications, as well as interventions to improve the quality of life of the CPI and patients in care, incorporating strategies to generate and/or increase their family and social support networks.PMID:38688187 | DOI:10.1016/j.aprim.2024.102948 (Source: Atencion Primaria)
Source: Atencion Primaria - April 30, 2024 Category: Primary Care Authors: Ricardo Alejandro S ánchez Bárcenas Daniel L ópez Hernández Leticia Brito-Aranda Brenda Berenice Garc ía Mantilla Mar ía Del Rocío Thompson Bonilla Ernestina Pav ón Delgado Luis Beltr án Lagunes Roberto Dur án Rojo Emmanuel Melgarejo-Estefan Tan Source Type: research
Hydralazine use can be associated with IgM-dominated immune complex-mediated glomerulonephritis
CONCLUSION: The hydralazine-induced autoimmune phenomenon can be seen in IgM-dominant ICMGN, which should be classified as a subtype of membranoproliferative glomerulonephritis.PMID:38685716 | DOI:10.1080/01913123.2024.2346660 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - April 30, 2024 Category: Pathology Authors: Ping L Zhang Brandon D Metcalf Sarang Khan Jamal Abukhaled Khalid Zafar Wei Li Hassan D Kanaan Source Type: research
Evaluation of the Efficacy and Safety of Tenofovir Disoproxil Fumarate in Intercepting Mother-to-Child Transmission of Hepatitis B Virus
This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment. Clinical and laboratory data of infants were assayed at delivery and 7-months post-partum visit and compared between the two groups. There was no difference in clinical characteristics of participants between the two groups. Ther...
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Dongxiang Han Jianxiu Du Wei Wang Cui Wang Source Type: research
'Playing catch-up': safety and optimal tackle outcomes in women's rugby union (PhD Academy Award)
Br J Sports Med. 2024 Apr 30:bjsports-2024-108251. doi: 10.1136/bjsports-2024-108251. Online ahead of print.NO ABSTRACTPMID:38688696 | DOI:10.1136/bjsports-2024-108251 (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - April 30, 2024 Category: Sports Medicine Authors: Kathryn Dane Source Type: research
