Am J Trop Med Hyg; +25 new citations
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/07/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - July 13, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Am J Trop Med Hyg; +16 new citations
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/07/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - July 4, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Case Report: Two Cases of Strongyloidiasis Presenting with Thrombotic Events.
We report two unusual cases of clinical strongyloidiasis that present as extensive thrombosis: a case of hyperinfection with concurrent eosinophilia and a case of disseminated infection as a complication of immunosuppression. We discuss risk factors for the development of Strongyloides stercoralis infection and thromboembolism, and the recommended management. PMID: 31218995 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Waters M, Krajden S, Kim C, Elsobky R, Lychacz B, Cheung M, Crowther M, Keystone J Tags: Am J Trop Med Hyg Source Type: research

Lateral Flow Dipstick Test for Serodiagnosis of Strongyloidiasis.
Abstract The conventional method of detecting Strongyloides stercoralis in fecal samples has poor diagnostic sensitivity. Detection of Strongyloides-specific antibodies increases the sensitivity; however, most tests are ELISAs that use parasite extract which may cross-react with the sera of other helminth infections. To improve the serological diagnosis of strongyloidiasis, this study aimed at developing a sensitive and specific lateral flow rapid dipstick test. Two recombinant proteins, recombinant NIE (rNIE) and rSs1a, were used in preparing the dipstick, with gold-conjugated antihuman IgG4 as detector reagent. ...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Yunus MH, Arifin N, Balachandra D, Anuar NS, Noordin R Tags: Am J Trop Med Hyg Source Type: research

Epidemiology and Pathogenesis of Providencia alcalifaciens Infections.
Abstract Providencia alcalifaciens is a member of the family Enterobacteriaceae that has been commonly implicated as a causative agent of diarrheal infection in humans and animals. Recent outbreaks of P. alcalifaciens in both developing and developed countries have raised public health concerns. Several studies have suggested that P. alcalifaciens can cause diarrhea by invading the intestinal mucosa, although its pathogenicity has not been well established. Often routine laboratory investigations that seek etiological agents of diarrhea do not actively pursue P. alcalifaciens detection. Therefore, routine laborato...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Shah MM, Odoyo E, Ichinose Y Tags: Am J Trop Med Hyg Source Type: research

Characterization of Plasmodium vivax pvmdr1 Polymorphisms in Isolates from Mangaluru, India.
Abstract India accounts for approximately half of the global Plasmodium vivax cases, but information as to the presence of chloroquine (CQ) resistance is scarce. In an observational study in Mangaluru, south-western India, of 116 vivax malaria patients analyzed, 89.5% (102/114) had cleared parasitemia on days two or three of CQ treatment. Two remaining patients presented on days four and five without parasitemia. One hundred eight isolates of these 116 patients were successfully sequenced for pvmdr1 polymorphisms. Eight non-synonymous polymorphisms but no wild-type isolate were detected. Ten pvmdr1 haplotypes were...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Tacoli C, Gai PP, Siegert K, Wedam J, Kulkarni SS, Rasalkar R, Boloor A, Jain A, Mahabala C, Baliga S, Shenoy D, Gai P, Devi R, Mockenhaupt FP Tags: Am J Trop Med Hyg Source Type: research

Prevalence and Genetic Characterization of Deer Tick Virus (Powassan Virus, Lineage II) in Ixodes scapularis Ticks Collected in Maine.
Abstract Deer tick virus (DTV) is a genetic variant of Powassan virus (POWV) that circulates in North America in an enzootic cycle involving the blacklegged or "deer tick," Ixodes scapularis, and small rodents such as the white-footed mouse. The number of reported human cases with neuroinvasive disease has increased substantially over the past few years, indicating that POWV may be of increasing public health importance. To this end, we sought to estimate POWV infection rates in questing I. scapularis collected from four health districts in Maine (York, Cumberland, Midcoast, and Central Maine). Infection...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Robich RM, Cosenza DS, Elias SP, Henderson EF, Lubelczyk CB, Welch M, Smith RP Tags: Am J Trop Med Hyg Source Type: research

In Situ Cellular Response Underlying Successful Treatment of Mucosal Leishmaniasis with a Combination of Pentavalent Antimonial and Pentoxifylline.
Abstract Mucosal leishmaniasis (ML) is characterized by high production of inflammatory cytokines. Administration of pentoxifylline (PTX), an inhibitor of TNF-alpha, with pentavalent antimony (Sbv), has been successfully used as alternative treatment for refractory ML. Our study aims to investigate the in situ cellular response underlying the effectiveness of this therapy, by evaluating the intensity of the inflammatory infiltrate, cellular composition, and expression of cytokines and granzyme A in lesions from ML before and after treatment with Sbv alone or in combination with PTX. Our data showed no differences ...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Rodrigues de Faria D, Barbieri LC, Koh CC, Lima Machado PR, Barreto CC, Figueiredo de Lima CM, Lessa MM, Carvalho E, Gollob KJ, Dutra WO Tags: Am J Trop Med Hyg Source Type: research

Prevalence of Enteropathogens in Outpatients with Acute Diarrhea from Urban and Rural Areas, Southeast China, 2010-2014.
Abstract Acute diarrhea is an important public health issue. Here, we focused on the differences of enteropathogens in acute diarrhea between urban and rural areas in southeast China. Laboratory- and sentinel-based surveillance of acute diarrhea (≥ 3 loose or liquid stools/24 hours) was conducted at 16 hospitals. Fecal specimens were tested for bacterial (Aeromonas sp., Campylobacter sp., diarrheagenic Escherichia coli, Plesiomonas shigelloides, non-typhoidal Salmonella, Shigella sp., Vibrio sp., and Yersinia sp.) and viral (adenovirus, astrovirus, Norovirus, Rotavirus, and Sapovirus) pathogens. Descriptive sta...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Chen C, Wang LP, Yu JX, Chen X, Wang RN, Yang XZ, Zheng SF, Yu F, Zhang ZK, Liu SJ, Li ZJ, Chen Y Tags: Am J Trop Med Hyg Source Type: research

Clinical and Diagnostic Features of 413 Patients Treated for Imported Strongyloidiasis at the Hospital for Tropical Diseases, London.
This study describes the clinical features of a cohort of imported cases of strongyloidiasis and the performance of standard diagnostic techniques for this condition. A total of 413 cases were identified, of whom 86 had microscopically proven infection. In proven cases, 23% had normal eosinophil counts, 19% had negative Strongyloides-specific serology, and 9.3% had normal blood counts and were seronegative. Serological testing was less sensitive for returning travelers (46.2%) than for migrants (89.7%). Immunosuppression, including human T-cell lymphotropic virus 1, was significantly associated with proven infection after ...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Ming DK, Armstrong M, Lowe P, Chiodini PL, Doherty JF, Whitty CJM, McGregor AC Tags: Am J Trop Med Hyg Source Type: research

Connecting Rural and Global Health Education for Workforce Development.
Abstract Healthcare workforce shortages are continuing to increase worldwide with more profound deficits seen in rural communities in both developed and developing countries. These deficits impede progress towards heath equity and global health initiatives including the 2030 Sustainable Development Goals. Medical training has supported the idea that having a rural background influences future practice in rural settings. With a majority of global health experiences taking place in rural settings, there is an opportunity for health profession programs to take advantage of expanding global health education to encoura...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Steeb DR, Dascanio SA, Kiser SN Tags: Am J Trop Med Hyg Source Type: research

Coinfection with Rickettsia monacensis and Orientia tsutsugamushi: A Case Report.
Abstract Rickettsia monacensis and Orientia tsutsugamushi are bacteria of the family Rickettsiaceae, which causes fever, rash, and eschar formation; outdoor activities are a risk factor for Rickettsiaceae infection. A 75-year-old woman presented with fever, rash, and eschar and was confirmed as being scrub typhus positive based on a nested-polymerase chain reaction (N-PCR) test for a 56-kDa gene of O. tsutsugamushi; the genome was identified as the Boryong genotype. In addition, a pan-Rickettsia real-time PCR test was positive and a N-PCR test using a Rickettsia-specific partial outer membrane protein A (rOmpA) co...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Kim SW, Kim CM, Kim DM, Yun NR Tags: Am J Trop Med Hyg Source Type: research

A Combination of Itraconazole and Amiodarone Is Highly Effective against Trypanosoma cruzi Infection of Human Stem Cell-Derived Cardiomyocytes.
Abstract Trypanosoma cruzi is the etiologic agent of Chagas disease (CD), which can result in severe cardiomyopathy. Trypanosoma cruzi is endemic to the Americas, and of particular importance in Latin America. In the United States and other non-endemic countries, rising case numbers have also been observed. The currently used drugs are benznidazole (BNZ) and nifurtimox, which have limited efficacy during chronic infection. We repurposed itraconazole (ICZ), originally an antifungal, in combination with amiodarone (AMD), an antiarrhythmic, with the goal of interfering with T. cruzi infection. Human pluripotent stem ...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Sass G, Madigan RT, Joubert LM, Bozzi A, Sayed N, Wu JC, Stevens DA Tags: Am J Trop Med Hyg Source Type: research

Secondary Prophylaxis with Liposomal Amphotericin B in a Patient with Mucosal Leishmaniasis Undergoing Immunobiological Therapy for Active Ankylosing Spondylitis.
to VS Abstract Immunosuppressive treatments for rheumatic diseases present special problems in areas endemic for chronic infectious diseases because of the possibility of reactivation. Leishmaniasis is a significant neglected tropical disease caused by different species of protozoan parasites within the genus Leishmania. Amastigotes live as intracellular parasites in a variety of mammalian cells, most notably within phagocytes such as macrophages, and residual parasites can persist even after treatment and healing of the lesions. We herein report a case of relapsing mucosal leishmaniasis after aggressive immunothe...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Nicodemo AC, de Andrade HF, Muñoz Torres P, Amato VS Tags: Am J Trop Med Hyg Source Type: research

Impact of Multiplicity of Plasmodium falciparum Infection on Clinical Disease in Malawi.
Abstract Multiplicity of infection (MOI), the number of unique Plasmodium falciparum parasite genotypes found in one infected individual, may contribute to the development of clinical malaria disease. However, the independent contribution of MOI and parasite density to clinical disease has not been well characterized. We conducted a two-year longitudinal cohort study of adults and children in a high-transmission setting in Malawi to test the hypothesis that increased MOI was independently associated with clinical disease, after accounting for parasite density. Of 1,062 episodes of infection, 477 (44.9%) were assoc...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Earland D, Buchwald AG, Sixpence A, Chimenya M, Damson M, Seydel K, Mathanga DP, Taylor TE, Laufer MK Tags: Am J Trop Med Hyg Source Type: research

Circulation of Rift Valley Fever Virus Antibody in Cattle during Inter-Epizootic/Epidemic Periods in Selected Regions of Tanzania.
Abstract Tanzania is one of the sub-Saharan countries that have experienced a number of Rift Valley fever (RVF) outbreaks at intervals of 10-20 years since the first isolation of the virus during the early 1930s. Recent studies have reported serological evidence of inter epizootic/epidemic period circulation of RVF virus (RVFV) in livestock and humans. The aim of this study was to conduct a cross-sectional survey in Tanzania during 2015/16 to further explore the possibility that RVFV was circulating among cattle during the Inter epizootic/epidemic period. A total of 443 cattle samples were collected in Manyara, Do...
Source: Am J Trop Med Hyg - June 17, 2019 Category: Infectious Diseases Authors: Salekwa LP, Wambura PN, Matiko MK, Watts DM Tags: Am J Trop Med Hyg Source Type: research

A Lesion in the Corpus Callosum due to Eosinophilic Meningitis Caused by Angiostrongylus cantonensis.
PMID: 31190682 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - June 1, 2019 Category: Infectious Diseases Authors: Chotmongkol V, Khamsai S Tags: Am J Trop Med Hyg Source Type: research

On the Ground in Malawi-First Typhoid Conjugate Vaccine Study in Africa.
PMID: 31190683 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - June 1, 2019 Category: Infectious Diseases Authors: Patel P, Patel P, Meiring JE, Misiri T, Mwakiseghile F, Gordon MA Tags: Am J Trop Med Hyg Source Type: research

Am J Trop Med Hyg; +27 new citations
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/05/29PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 29, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Am J Trop Med Hyg; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/05/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 24, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Pyemotes ventricosus Dermatitis: A Serpiginous Skin Lesion due to a Mite that Parasitizes a Wood-Boring Beetle.
PMID: 31088603 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 1, 2019 Category: Infectious Diseases Authors: Neumayr A, Kuenzli E Tags: Am J Trop Med Hyg Source Type: research

Successful Treatment of Localized Cutaneous Melioidosis with Oral Antibiotic Therapy Alone.
PMID: 31088604 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 1, 2019 Category: Infectious Diseases Authors: Smith S, Hanson J Tags: Am J Trop Med Hyg Source Type: research

Frontier Warriors-Combating Cholera in Rural India.
PMID: 31088605 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 1, 2019 Category: Infectious Diseases Authors: Viswanathan R, Kumar A Tags: Am J Trop Med Hyg Source Type: research

Acute Esophageal Necrosis Associated with Strongyloides stercoralis Hyperinfection.
PMID: 31088606 [PubMed - in process] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - May 1, 2019 Category: Infectious Diseases Authors: Tomori M, Mukaigawara M, Narita M Tags: Am J Trop Med Hyg Source Type: research

Anemia, Iron Deficiency, and Iron Supplementation in Relation to Mortality among HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy in Tanzania.
We examined the associations of anemia severity and iron deficiency anemia (IDA) at HAART initiation and during monthly prospective follow-up with mortality among 40,657 adult HIV-infected patients receiving HAART in Dar es Salaam, Tanzania. Proportional hazards models were used to examine the associations of anemia severity and IDA at HAART initiation and during follow-up with mortality. A total of 6,261 deaths were reported. Anemia severity at HAART initiation and during follow-up was associated with an increasing risk of mortality (trend tests P
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Haider BA, Spiegelman D, Hertzmark E, Sando D, Duggan C, Makubi A, Sudfeld C, Aris E, Chalamilla GE, Fawzi WW Tags: Am J Trop Med Hyg Source Type: research

Evaluation of an Emergency Bulk Chlorination Project Targeting Drinking Water Vendors in Cholera-Affected Wards of Dar es Salaam and Morogoro, Tanzania.
Abstract In August 2015, an outbreak of cholera was reported in Tanzania. In cholera-affected areas of urban Dar es Salaam and Morogoro, many households obtained drinking water from vendors, who sold water from tanks ranging in volume from 1,000 to 20,000 L. Water supplied by vendors was not adequately chlorinated. The Tanzanian Ministry of Health, Community Development, Gender, Elderly and Children and the U.N. Children's Fund, Tanzania, collaborated to enroll and train vendors to treat their water with 8.68-g sodium dichloroisocyanurate tablets. The CDC provided monitoring and evaluation support. Vendors were pr...
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Rajasingham A, Hardy C, Kamwaga S, Sebunya K, Massa K, Mulungu J, Martinsen A, Nyasani E, Hulland E, Russell S, Blanton C, Nygren B, Eidex R, Handzel T Tags: Am J Trop Med Hyg Source Type: research

Antibiotic-Resistant Escherichia coli in Drinking Water Samples from Rural Andean Households in Cajamarca, Peru.
This study aimed at identifying fecal pathogens in drinking water obtained from rural Andean households from Cajamarca, Peru, and measuring the antibiotic resistance profile of Escherichia coli. The study was embedded within a community-randomized controlled trial among 102 communities in the northern highlands of the Cajamarca region, Peru. Of 314 samples, 55.4% (95% CI [49.7, 61.0], n = 174) were identified as thermotolerant coliforms. Among the samples positive for thermotolerant coliform, E. coli was isolated in 37.3% (n = 117), Klebsiella spp. in 8.0% (n = 25), Enterobacter spp. in 5.1% (n = 16), and Citrobacter spp. ...
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Larson A, Hartinger SM, Riveros M, Salmon-Mulanovich G, Hattendorf J, Verastegui H, Huaylinos ML, Mäusezahl D Tags: Am J Trop Med Hyg Source Type: research

Molecular Survey of Bartonella Species in Shelter Cats in Rio De Janeiro: Clinical, Hematological, and Risk Factors.
ni CD Abstract The present study aimed to detect Bartonella DNA in cats belonging to shelters, and to evaluate risk factors, clinical signs, and hematological abnormalities associated with infection. Complete blood counts and screening for the presence of Bartonella DNA were performed on cats' ethylenediamine tetraacetic acid anticoagulant-blood samples. Eighty-three cats (39.9%) were positive for Bartonella species. Bartonella DNA was also detected in fleas and in the blood of cats infested by positive flea. Cats that had not been sterilized, had outdoor access, had histories of fights, and had concurrent flea in...
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Raimundo JM, Guimarães A, Amaro GM, da Silva AT, Botelho CFM, Massard CL, de Lemos ERS, Favacho ARM, Baldani CD Tags: Am J Trop Med Hyg Source Type: research

Neutralizing Antibodies from Convalescent Chikungunya Virus Patients Can Cross-Neutralize Mayaro and Una Viruses.
This study examined whether antibodies from convalescent CHIKV patients could cross-neutralize UNAV and MAYV. Considerable cross-neutralization of both viruses was observed, suggesting that exposure to CHIKV can produce antibodies that may mitigate infection to UNAV or MAYV. Understanding the impact of CHIKV exposure on population susceptibility to other emerging viruses may help predict outbreaks; moreover, identification of cross-reactive immune responses among alphaviruses may lead to the development of vaccines targeting multiple viruses. PMID: 31017081 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Martins KA, Gregory MK, Valdez SM, Sprague TR, Encinales L, Pacheco N, Cure C, Porras-Ramirez A, Rico-Mendoza A, Chang A, Pitt ML, Nasar F Tags: Am J Trop Med Hyg Source Type: research

Transmission Routes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in a Neonatology Ward in Madagascar.
Abstract The diffusion of extended-spectrum beta-lactamase (E-ESBL)-producing Enterobacteriaceae is a major concern worldwide, especially in low-income countries, where they may lead to therapeutic failures. In hospitals, where colonization is the highest, E-ESBL transmission is poorly understood, limiting the possibility of establishing effective control measures. We assessed E-ESBL-acquisition routes in a neonatalogy ward in Madagascar. Individuals from a neonatology ward were longitudinally followed-up (August 2014-March 2015). Newborns' family members' and health-care workers (HCWs) were stool-sampled and test...
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Bonneault M, Andrianoelina VH, Herindrainy P, Noah Rabenandrasana MA, Garin B, Breurec S, Delarocque-Astagneau E, Guillemot D, Andrianirina ZZ, Collard JM, Huynh BT, Opatowski L Tags: Am J Trop Med Hyg Source Type: research

Multiple Praziquantel Treatments of Schistosoma mansoni Egg-Negative, CCA-Positive Schoolchildren in a Very Low Endemic Setting in Egypt Do Not Consistently Alter CCA Results.
Abstract Forty-four Schistosoma mansoni egg-negative/circulating cathodic antigen (CCA) low-positive (trace or 1+) children in three districts of very low prevalence in Egypt were given three sequential praziquantel (PZQ) treatments. Stool and urine specimens were collected 3 months following the initial treatment, and 3 weeks following the second and following the third PZQ treatments, which were conducted 5 weeks apart. Stool specimens were examined by Kato-Katz (four slides/stool sample) and all S. mansoni egg-negative stools were further tested by the "miracidia hatching test" (MHT). Urine samples we...
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Haggag AA, Casacuberta Partal M, Rabiee A, Abd Elaziz KM, Campbell CH, Colley DG, Ramzy RMR Tags: Am J Trop Med Hyg Source Type: research

Beyond Blood Smears-Qualification of the Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.
This study led to biomarker qualification through the U.S. Food and Drug Administration for use in CHMI studies at non-endemic sites, which will facilitate biomarker use for the qualified context of use in drug and vaccine trials. PMID: 31017084 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 22, 2019 Category: Infectious Diseases Authors: Seilie AM, Chang M, Hanron AE, Billman ZP, Stone BC, Zhou K, Olsen TM, Daza G, Ortega J, Cruz K, Smith N, Healy SA, Neal J, Wallis CK, Shelton L, Mankowski TV, Wong-Madden S, Mikolajczak SA, Vaughan AM, Kappe SHI, Fishbaugher M, Betz W, Kennedy M, Hume JC Tags: Am J Trop Med Hyg Source Type: research

Am J Trop Med Hyg; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/04/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 19, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Am J Trop Med Hyg; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/04/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 18, 2019 Category: Infectious Diseases Tags: Report Source Type: research

Efficacy of the SuperTowel ®: An Alternative Hand-washing Product for Humanitarian Emergencies.
Efficacy of the SuperTowel®: An Alternative Hand-washing Product for Humanitarian Emergencies. Am J Trop Med Hyg. 2019 Mar 11;: Authors: Torondel B, Khan R, Holm Larsen T, White S Abstract Handwashing with soap reduces the transmission of diarrheal pathogens, but access to hand-washing facilities, water, and soap in humanitarian emergencies is limited. The SuperTowel® (ST) is a fabric treated with permanent antimicrobial bonding and has been designed as a soap alternative in emergency situations. The aim of this study was to test the efficacy of the ST as a hand-cleaning product. Two sets of l...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Torondel B, Khan R, Holm Larsen T, White S Tags: Am J Trop Med Hyg Source Type: research

Global Outbreaks and Origins of a Chikungunya Virus Variant Carrying Mutations Which May Increase Fitness for Aedes aegypti: Revelations from the 2016 Mandera, Kenya Outbreak.
Abstract In 2016, a chikungunya virus (CHIKV) outbreak was reported in Mandera, Kenya. This was the first major CHIKV outbreak in the country since the global reemergence of this virus in Kenya in 2004. We collected samples and sequenced viral genomes from this outbreak. All Kenyan genomes contained two mutations, E1:K211E and E2:V264A, recently reported to have an association with increased infectivity, dissemination, and transmission in the Aedes aegypti vector. Phylogeographic inference of temporal and spatial virus relationships showed that this variant emerged within the East, Central, and South African linea...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Maljkovic Berry I, Eyase F, Pollett S, Konongoi SL, Joyce MG, Figueroa K, Ofula V, Koka H, Koskei E, Nyunja A, Mancuso JD, Jarman RG, Sang R Tags: Am J Trop Med Hyg Source Type: research

Cardiac Involvement in Travelers with Enteric Fever.
Abstract Data regarding cardiac involvement in enteric fever among travelers are scarce. In this retrospective study, 59 patients were hospitalized with enteric fever during 2004-2017 and 28 had cardiac workups. Among those, four had evidence of cardiac involvement, including clinical myocarditis, electrocardiogram changes, or troponin elevation. Cardiac involvement was higher among patients infected with Salmonella Typhi than with Salmonella Paratyphi A (P = 0.08), with a significant relative risk of 6 (95% CI: 1.15-31.22, P = 0.03). Time from symptoms onset to effective treatment was longer for patients with car...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Biber A, Nof E, Schwartz E Tags: Am J Trop Med Hyg Source Type: research

Case Report: Ocular Toxocariasis: A Report of Three Cases from the Mississippi Delta.
We report three cases of ocular toxocariasis in individuals from the Mississippi Delta, a rural community with prevalent poverty. Visual acuity was severely affected in two of the three cases. Increased awareness of ocular toxocariasis, which may have under-recognized frequency, will contribute to prompt diagnosis and treatment, which will ultimately improve patient health in the region. PMID: 30860012 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Inagaki K, Kirmse B, Bradbury RS, Moorthy RS, Arguello I, Mcguffey CD, Tieu B, Hobbs CV Tags: Am J Trop Med Hyg Source Type: research

Prevalence of and Risk Factors Associated with Polymerase Chain Reaction-Determined Plasmodium falciparum Positivity on Day 3 after Initiation of Artemether-Lumefantrine Treatment for Uncomplicated Malaria in Bagamoyo District, Tanzania.
on A Abstract Prevalence of and risk factors associated with polymerase chain reaction (PCR)-determined Plasmodium falciparum positivity were assessed on day 3 after initiation of treatment, pre-implementation and up to 8 years post-deployment of artemether-lumefantrine as first-line treatment for uncomplicated malaria in Bagamoyo district, Tanzania. Samples originated from previously reported trials conducted between 2006 and 2014. Cytochrome b-nested PCR was used to detect malaria parasites from blood samples collected on a filter paper on day 3. Chi-square and McNemar chi-squared tests, logistic regression mode...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Mwaiswelo R, Ngasala B, Jovel I, Xu W, Larson E, Malmberg M, Gil JP, Premji Z, Mmbando BP, Mårtensson A Tags: Am J Trop Med Hyg Source Type: research

Complex Epidemiological Dynamics of Eastern Equine Encephalitis Virus in Florida.
In this study, we further characterized the epidemiological and evolutionary dynamics of EEEV in Florida. Epidemiological analysis of sentinel chicken seroconversion rates to EEEV infections during 2005-2016 suggested significant seasonality of EEEV activity in Florida. We observed significant annual activity of EEEV in the North and North Central regions, with little significant seasonality in the Panhandle region. Phylogenetic analysis of complete EEEV genome sequences from different host sources and regions in Florida during 1986-2014 revealed extensive genetic diversity and spatial dispersal of the virus within Florida...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Heberlein-Larson LA, Tan Y, Stark LM, Cannons AC, Shilts MH, Unnasch TR, Das SR Tags: Am J Trop Med Hyg Source Type: research

Case Report: Hyperreactive Malarial Splenomegaly Syndrome Diagnosed with Loop-Mediated Isothermal Amplification and Treated with Artemisinin-Based Combination Therapy.
We describe the case of a 16-year-old patient, who recently arrived in Belgium from Guinea with a history of splenomegaly and B symptoms in whom HMSS diagnosis was achieved, thanks to the loop-mediated isothermal amplification method. To our knowledge, this is also the first described case treated by dihydroartemisinin/piperaquine. PMID: 30860015 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Genderini FG, Haeseleer C, Cantinieaux B, Martin C Tags: Am J Trop Med Hyg Source Type: research

Falsified and Substandard Drugs: Stopping the Pandemic.
Abstract Falsified and substandard medicines are associated with tens of thousands of deaths, mainly in young children in poor countries. Poor-quality drugs exact an annual economic toll of up to US$200 billion and contribute to the increasing peril of antimicrobial resistance. The WHO has emerged recently as the global leader in the battle against poor-quality drugs, and pharmaceutical companies have increased their roles in assuring the integrity of drug supply chains. Despite advances in drug quality surveillance and detection technology, more efforts are urgently required in research, policy, and field monitor...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Nayyar GML, Breman JG, Mackey TK, Clark JP, Hajjou M, Littrell M, Herrington JE Tags: Am J Trop Med Hyg Source Type: research

Community-Led Total Sanitation Moves the Needle on Ending Open Defecation in Zambia.
Abstract Community-Led Total Sanitation Moves the Needle on Ending Open Defecation in Zambia. PMID: 30860017 [PubMed - as supplied by publisher] (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Brown J, Albert J, Whittington D Tags: Am J Trop Med Hyg Source Type: research

Gamma Irradiation as an Effective Method for Inactivation of Emerging Viral Pathogens.
Abstract Gamma irradiation using a cobalt-60 source is a commonly used method for the inactivation of infectious specimens to be handled safely in subsequent laboratory procedures. Here, we determined irradiation doses to safely inactivate liquid proteinaceous specimens harboring different emerging/reemerging viral pathogens known to cause neglected tropical and other diseases of regional or global public health importance. By using a representative arenavirus, bunyavirus, coronavirus, filovirus, flavivirus, orthomyxovirus, and paramyxovirus, we found that these enveloped viruses differed in their susceptibility t...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Feldmann F, Shupert WL, Haddock E, Twardoski B, Feldmann H Tags: Am J Trop Med Hyg Source Type: research

Congenital Malaria in Newborns Attending Tororo General Hospital in Uganda: A Cross-Sectional Study.
This study aimed to determine the prevalence, to describe the clinical presentation, and to examine factors associated with congenital malaria in newborns aged up to 7 days attending Tororo General Hospital in Uganda. A total of 261 mother/baby pairs were recruited in this cross-sectional study. Giemsa-stained thick blood smears for malaria parasites and rapid malaria diagnostic tests were performed on capillary blood samples from all newborns and mothers, as well as on placental and cord samples from newborns delivered in the hospital. The prevalence of congenital malaria in the newborns was 16/261 (6.1%). No single clini...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Hangi M, Achan J, Saruti A, Quinlan J, Idro R Tags: Am J Trop Med Hyg Source Type: research

Case Report: Rare Presentation of Multivisceral Echinococcosis.
Abstract Cystic echinococcosis (CE) is a common, chronic, and endemic zoonotic disease usually localized in a single organ; multivisceral cases are rare, especially outside the liver or lung. Here, we describe an unusual case of a 43-year-old Tibetan man with echinococcosis of the infratemporal fossa, heart, liver, pancreas, abdomen, and pelvic cavity. He only presented with diminished vision of the left eye, especially when chewing. Computed tomography and magnetic resonance imaging revealed multivisceral CE. The patient underwent surgery for the excision of a cyst in the infratemporal fossa, as well as chemother...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Cai X, Cai H, Gan Q, Chang W, Yuan F, Luo W, Sun J, An J Tags: Am J Trop Med Hyg Source Type: research

Forest Goers and Multidrug-Resistant Malaria in Cambodia: An Ethnographic Study.
Abstract Multidrug-resistant Plasmodium falciparum malaria on the Cambodia-Thailand border is associated with working in forested areas. Beyond broad recognition of "forest-going" as a risk factor for malaria, little is known about different forest-going populations in this region. In Oddar Meanchey Province in northwestern Cambodia, qualitative ethnographic research was conducted to gain an in-depth understanding of how different populations, mobility and livelihood patterns, and activities within the forest intersect with potentiate malaria risk and impact on the effectiveness of malaria control and el...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Bannister-Tyrrell M, Gryseels C, Sokha S, Dara L, Sereiboth N, James N, Thavrin B, Ly P, Soy Ty K, Grietens KP, Sovannaroth S, Yeung S Tags: Am J Trop Med Hyg Source Type: research

Determination of Optimal Diagnostic Cut-Offs for the Naval Medical Research Centre Scrub Typhus IgM ELISA in Chiang Rai, Thailand.
Abstract In this diagnostic accuracy study, we evaluated data from 135 febrile patients from Chiang Rai, to determine the optimal optical density (OD) cutoffs for an in-house scrub typhus IgM ELISA. Receiver operating characteristic curves were generated using a panel of reference assays, including an IgM immunofluorescence assay (IFA), PCR, in vitro isolation, presence of an eschar, or a combination of these. Altogether, 33 patients (24.4%) were diagnosed as having scrub typhus. Correlation between positivity by IFA and increasing OD values peaked at a cutoff of 2.0, whereas there was little association between p...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Phanichkrivalkosil M, Tanganuchitcharnchai A, Jintaworn S, Kantipong P, Laongnualpanich A, Chierakul W, Paris DH, Richards AL, Wangrangsimakul T, Day NPJ, Blacksell SD Tags: Am J Trop Med Hyg Source Type: research

Homelessness and HIV: A Combination Predictive of Poor Tuberculosis Treatment Outcomes and in Need of Innovative Strategies to Improve Treatment Completion.
L, Rueda ZV Abstract Antioquia Department is the state with the highest burden of tuberculosis (TB) in Colombia. Our aim was to determine the risk factors associated with unsuccessful TB treatment in HIV-seropositive and homeless persons, compared with non-HIV-infected and non-homeless persons with TB. We conducted a retrospective cohort study using observational, routinely collected health data from all drug-susceptible TB cases in homeless and/or HIV-seropositive individuals in Antioquia from 2014 to 2016. Unsuccessful TB treatment was defined as individuals having been lost to follow-up, having died, or treatme...
Source: Am J Trop Med Hyg - March 11, 2019 Category: Infectious Diseases Authors: Gómez LM, Paniagua-Saldarriaga LA, Richert Q, Keynan Y, Montes F, López L, Rueda ZV Tags: Am J Trop Med Hyg Source Type: research

Am J Trop Med Hyg; +23 new citations
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2019/03/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - March 9, 2019 Category: Infectious Diseases Tags: Report Source Type: research