Pregnancy, puerperium and perinatal constipation - an observational hybrid survey on pregnant and postpartum women and their age-matched non-pregnant controls.
i M Abstract OBJECTIVE: To evaluate the prevalence of constipation during pregnancy and early puerperium. DESIGN: Observational survey. SETTING: Secondary and tertiary hospital in Finland. POPULATION: Pregnant (N=474) and postpartum (N=403) women and a control group of 200 non-pregnant women who did not give birth within a past year. METHODS: Women reported bowel function and other gastrointestinal symptoms with a structured questionnaire using 11-point numerical rating scale (0=no symptom, 10=most severe symptom) and binominal yes/no questions during the second and third trimesters and few day...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 8, 2020 Category: OBGYN Authors: Kuronen M, Hantunen S, Alanne L, Kokki H, Saukko C, Sjövall S, Vesterinen K, Kokki M Tags: BJOG Source Type: research

What is the rate of caesarean section on maternal request, and how does it differ between countries?
PMID: 33026705 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 7, 2020 Category: OBGYN Authors: Jardine JE Tags: BJOG Source Type: research

Re: Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial.
PMID: 33027546 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 7, 2020 Category: OBGYN Authors: Mirza E, Hanif M, Khan MA, Jaleel S Tags: BJOG Source Type: research

During the second wave of COVID-19, don't forget about influenza: a call to action.
Abstract Having lived through the havoc of COVID-19 in a hospital situated in one of the hardest hit zip codes in the United States, the thought that another wave could loom in the fall is bracing. Further, we are acutely aware of the herculean effort it took to reorganize the service to accommodate the needs of women infected with this new pathogen. PMID: 33025694 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 6, 2020 Category: OBGYN Authors: Atallah F, Minkoff H Tags: BJOG Source Type: research

Detection of SARS-CoV-2 in vaginal swabs of women with acute SARS-CoV-2 infection: a prospective study.
CONCLUSION: Our findings contradict most previous reports, which did not detect the presence of viral colonization in the vagina. Although passage through the birth canal exposes neonates to the vaginal polymicrobial flora, an acquisition of pathogens does not necessarily mandate neonatal infection or clinical disease. Nevertheless, when delivering a woman with acute SARS-CoV-2 infection, a clinician should consider the possibility of vaginal colonization, even if it is uncommon. PMID: 33021026 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 5, 2020 Category: OBGYN Authors: Schwartz A, Yogev Y, Zilberman A, Alpern S, Many A, Yousovich R, Gamzu R Tags: BJOG Source Type: research

Incidence and associated predictors of adverse pregnancy outcomes of maternal syphilis in China, 2016-2019: a cox regression analysis.
CONCLUSIONS: China has made huge progress over the last decades in PMTCT of syphilis, but the incidence of APOs among pregnant women infected with syphilis remains high. It is extremely essential to further strengthen access to early detection and standardized treatment of infected women to reduce the risk of APOs. PMID: 33021043 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 5, 2020 Category: OBGYN Authors: Li Z, Wang Q, Qiao Y, Wang X, Jin X, Wang A Tags: BJOG Source Type: research

The effect of polycystic ovary syndrome (PCOS) without hyperandrogenism on pregnancy-related outcomes: a retrospective cohort study.
CONCLUSION: PCOS patients without hyperandrogenism may achieve higher rates of clinical pregnancy and cumulative live birth than those without PCOS, without increases in their rates of biochemical pregnancy, pregnancy loss or other abnormal perinatal outcomes. PMID: 33021046 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 5, 2020 Category: OBGYN Authors: Hu S, Xu B, Long R, Jin L Tags: BJOG Source Type: research

Planned Oocyte Cryopreservation (Planned OC): Systematic Review and Meta-analysis of Cost-Efficiency and Patients' perspective.
CONCLUSION: Planned OC is an adequate method for preserving fertility. However, knowledge gaps result in under-utilization leading to reduced cost-efficiency . PMID: 33021076 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 5, 2020 Category: OBGYN Authors: Fuchs Weizman N, Baram S, Montbriand J, Librach CL Tags: BJOG Source Type: research

Vaginal Er:YAG LASER application in the menopausal ewe model: a randomised oestrogen and sham controlled trial.
Abstract OBJECTIVE: To describe effects of non-ablative Er:YAG LASER on vaginal atrophy induced by iatrogenic menopause in the ewe. DESIGN: Animal experimental, randomised, sham and oestrogen-treatment controlled study with blinding for primary outcome. SETTING: KU Leuven, Belgium. SAMPLE: Twenty-four ewes METHODS: Menopause was surgically induced, after which the ewes were randomised to three groups receiving either (1) vaginal Er:YAG LASER application three times, with a one-month interval; (2) three sham manipulations with a month interval; or (3) oestrogen replacement and sham manipulations. At ...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 4, 2020 Category: OBGYN Authors: Mackova K, Mazzer AM, Mori Da Cunha MGMC, Hajkova Hympanova L, Urbankova I, Willem Kastelein A, Vodegel E, Vander Linden K, Fehervary H, Guler Z, Paul Roovers J, Krofta L, Verhaeghe J, Deprest J Tags: BJOG Source Type: research

Pregnant women's use of e-cigarettes in the UK: a cross-sectional survey.
CONCLUSIONS: One in twenty pregnant women report vaping, most also smoke. Dual users are more motivated towards stopping smoking than smokers. Where women have tried, but cannot stop smoking, clinicians could encourage them to consider vaping for smoking cessation. PMID: 33012050 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 3, 2020 Category: OBGYN Authors: Bowker K, Lewis S, Phillips L, Orton S, Ussher M, Naughton F, Bauld L, Coleman T, Sinclair L, McRobbie H, Khan A, Cooper S Tags: BJOG Source Type: research

Association of Placenta-Derived Extracellular Vesicles with Preeclampsia and Associated Hypercoagulability: A clinical observational study.
Abstract OBJECTIVE: Preeclampsia (PE) is a pregnancy-associated condition initiated by placental factors. We have demonstrated that placental extracellular vesicles (pcEVs) cause hypertension and proteinuria in pregnant and non-pregnant mice. STUDY DESIGN: An observational study with both case-control and longitudinal designs. SETTING: A single center at the Department of Obstetrics and Gynecology, Tianjin Medical University. POPULATION: We collected blood samples and clinical information from 54 PE patients, 33 normally pregnant women with at 30-36 gestational weeks and on postpartum days 1 and 4 f...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 2, 2020 Category: OBGYN Authors: Chen Y, Huang P, Han C, Li J, Liu L, Zhao Z, Gao Y, Qin Y, Xu Q, Yan Y, Wang Y, Ren J, Men J, Dong JF, Zhang J, Xue F Tags: BJOG Source Type: research

No-fault compensation for cerebral palsy associated with pregnancy care in Japan.
PMID: 33006804 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 1, 2020 Category: OBGYN Authors: Ushiro S, Steer PJ Tags: BJOG Source Type: research

Improved stillbirth risk stratification, an urgent global need.
Abstract Stillbirth is among the most devastating pregnancy complications and is also one of the hardest complications to predict. Traditionally, stillbirth risk stratification has incorporated maternal demographic characteristics such as age and ethnicity as well as medical and pregnancy conditions including multiple gestation, chronic hypertension and pregestational diabetes. While these are clear risk factors for stillbirth, they are nonspecific and are often present in live births. PMID: 33006825 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 1, 2020 Category: OBGYN Authors: Page J Tags: BJOG Source Type: research

COVID-19 Pandemic Practice Changes: More Harm than Good?
Abstract In response to the Coronavirus-2019 (COVID-19) pandemic, sweeping changes were made to obstetric care. Many practices rapidly converted to telehealth visits or drive-through obstetric services (Turrentine M et al, Obstet Gynecol 2020; 136(1):29-32). Others modified out-patient care practices such as reducing the number of ultrasounds or antenatal surveillance visits. In the manuscript by van-de-I'Isle and colleagues, the authors evaluated if a change to gestational diabetes (GDM) screening guidelines suggested by the Royal College of Obstetricians and Gynaecologists (RCOG) during the COVID-19 pandemic cha...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 1, 2020 Category: OBGYN Authors: Metz TD Tags: BJOG Source Type: research

Understanding the magnitude of risk associated with Zika virus infection in pregnancy.
Abstract In any pandemic, accurate data regarding adverse perinatal outcomes are critical to clinical management, a current reality with COVID-19. During the Zika virus epidemic, initial data regarding perinatal infection risks were concerning, with adverse pregnancy outcomes reported among 46.7% of affected pregnancies (Brasil et al NEJM 2016; 375: 2321). However, subsequent data demonstrated that the incidence of birth defects attributable to Zika virus was approximately 6%, with most of the risk occurring from first trimester infection (Honein et al JAMA 2017;317: 59). These s...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 1, 2020 Category: OBGYN Authors: Prabhu M, Riley LE Tags: BJOG Source Type: research

Corrigendum.
Authors: PMID: 32939970 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 18, 2020 Category: OBGYN Tags: BJOG Source Type: research

New gynaecological technologies - proper evaluation needed before implementation into clinical practice.
PMID: 32939972 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 18, 2020 Category: OBGYN Authors: Chien P Tags: BJOG Source Type: research

Benefit of Antenatal Corticosteroids by Year of Birth Among Preterm Infants in Canada During 2003-2017: A Population-Based Cohort Study.
CONCLUSION: Despite the ongoing improvements in neonatal care of preterm infants, as reflected by the gradual decrease in the absolute rates of neonatal mortality and severe neurological injury, the association of ACS treatment with neonatal mortality and severe neurological injury among extremely preterm infants born at 23-30 weeks' gestation has remained stable throughout the study period of 15 years. PMID: 32936996 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 15, 2020 Category: OBGYN Authors: Melamed N, Murphy K, Barrett J, Asztalos E, McDonald SD, Yoon EW, Shah PS, Canadian Neonatal Network (CNN), Canadian Preterm Birth Network (CPTBN) Investigators, Prakesh S Shah Mount Sinai Hospital, Makary H, Chandra S, Mundle W, Whittle W Tags: BJOG Source Type: research

Maternal infections: revisiting the need for screening in pregnancy.
This article is a critical appraisal of epidemiological data and current international screening recommendations for infections in pregnancy. PMID: 32937015 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 15, 2020 Category: OBGYN Authors: Faure-Bardon V, Ville Y Tags: BJOG Source Type: research

Implications for HPV positive women.
Abstract HPV Primary Screening has now been fully rolled out in England but there is still a way to go optimising the programme. It is only in recent years that women have been aware that cervical cancer is caused by a sexually transmitted infection. There was little stigma associated with abnormal cytology, but receiving a positive HPV result is new territory for most women. PMID: 32939965 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 15, 2020 Category: OBGYN Authors: Gilham C Tags: BJOG Source Type: research

Fetal Medicine Specialists' experiences of providing a new service of termination of pregnancy for fatal fetal anomaly: A qualitative study.
CONCLUSIONS: Our study identified challenges regarding the suitability of the Irish legislation for TOPFA and its rapid introduction into clinical practice. It illustrates the importance of institutional and peer support as well as the need for supportive management in the provision of a new service. PMID: 32935467 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Power S, Meaney S, O'Donoghue K Tags: BJOG Source Type: research

Role of carbon nanoparticle suspension in sentinel lymph node biopsy for early-stage cervical cancer: a prospective study.
Abstract OBJECTIVE: To evaluate the clinical diagnostic validity of carbon nanoparticle suspension (CNS) in sentinel lymph node biopsy (SLNB) for assessing lymphatic spread of early-stage cervical cancer. DESIGN: A prospective study. SETTING AND POPULATION: 356 cases. METHODS: We enrolled 356 stage Ia2-IIa2 cervical cancer patients to undergo SLNB using CNS, followed by systematic pelvic lymphadenectomy. All lymph node specimens were assessed using conventional histopathologic ± pathologic ultrastaging analyses. MAIN OUTCOME MEASURES: SLN detection rate (DR), clinical diagnostic validity...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Ya X, Qian W, Huiqing L, Haixiao W, Weiwei Z, Jing B, Lei C, Jianping Y, Shuping Y, Jiaya M, Dong W, Ruixia G Tags: BJOG Source Type: research

External validation of models to predict the outcome of pregnancies of unknown location: a multicentre cohort study.
CONCLUSIONS: 2ST and M6P performed best to predict and triage PUL. PMID: 32931087 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Christodoulou E, Bobdiwala S, Kyriacou C, Farren J, Mitchell-Jones N, Ayim F, Chohan B, Abughazza O, Guruwadahyarhalli B, Al-Memar M, Guha S, Vathanan V, Gould D, Stalder C, Wynants L, Timmerman D, Bourne T, Van Calster B Tags: BJOG Source Type: research

Association between extremely preterm caesarean delivery and maternal depressive and anxious symptoms: a national population-based cohort study.
CONCLUSIONS: Mothers having caesarean delivery before 26 weeks' gestation are at high risk of depressive symptoms and may benefit from specific preventive care. PMID: 32931138 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Blanc J, Rességuier N, Lorthe E, Goffinet F, Sentilhes L, Auquier P, Tosello B, d'Ercole C Tags: BJOG Source Type: research

Maternal risk of hypertension 7-15 Years after pregnancy: clues from the placenta.
CONCLUSIONS: PE-related placental/extraplacental membrane findings help risk stratify women with moderately-elevated BP in pregnancy for later development of hypertension. PMID: 32931608 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Holzman CB, Senagore P, Xu J, Dunietz GL, Strutz KL, Tian Y, Bullen BL, Eagle M, Catov JM Tags: BJOG Source Type: research

Prediction of stillbirth: an umbrella review of evaluation of prognostic variables.
CONCLUSION: We have identified variables relevant to the development of prediction models for stillbirth. Age, parity and prior adverse pregnancy outcomes had a more convincing association than the best performing tests which were PAPP-A, PlGF and UtAD. The evidence was limited by high heterogeneity and lack of data on intervention bias. PMID: 32931648 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Townsend R, Sileo FG, Allotey J, Dodds J, Heazell A, Jorgensen L, Kim VB, Magee L, Mol B, Sandall J, Smith G, Thilaganathan B, von Dadelszen P, Thangaratinam S, Khalil A Tags: BJOG Source Type: research

Cervical cancer prevention in transgender men: a review.
Abstract There is increased awareness of transgender physical and mental health widely and in academic research. A significant proportion of transgender men will retain their cervix with an increased risk of cervical cancer. In this review of cervical cancer screening among transgender men, we try to estimate how many transgender men still have a cervix, understand to identify challenges and barriers to cervical screening and propose possible solutions. Organised cervical screening programmes need to consider the needs of this population, in particular the provison of HPV self-sampling. PMID: 32931650 [PubMed...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 14, 2020 Category: OBGYN Authors: Weyers S, Garland SM, Cruickshank M, Kyrgiou M, Arbyn M Tags: BJOG Source Type: research

Global incidence of Caesarean deliveries on maternal request: a systematic review and meta-regression.
CONCLUSIONS: An appropriate reporting of CDMR should be a key priority in maternal health policies and practices. PMID: 32929868 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 13, 2020 Category: OBGYN Authors: Begum T, Saif-Ur-Rahman KM, Yaqoot F, Stekelenburg J, Anuradha S, Biswas T, Doi SA, Mamun AA Tags: BJOG Source Type: research

Cranial findings detected by second trimester ultrasound in fetuses with myelomeningocele: a systematic review.
Abstract BACKGROUND: Abnormal intracranial findings are often detected at mid-trimester ultrasound (US) in fetuses with MMC. It is unclear whether these findings constitute a spectrum of the disease or are an independent finding, which should contraindicate fetal surgery. OBJECTIVE: To ascertain the spectrum and frequency of US detected cranial findings in MMC fetuses. SEARCH STRATEGY: MEDLINE, Embase, Web of Science and CENTRAL search, January 2000-June 2020. SELECTION CRITERIA: Study reporting incidence of cranial US findings in consecutive cases of second trimester MMC fetuses. DATA COLLECTI...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 13, 2020 Category: OBGYN Authors: Kunpalin Y, Richter J, Mufti N, Bosteels J, Ourselin S, De Coppi P, Thompson D, David AL, Deprest J Tags: BJOG Source Type: research

Increasing caesarean delivery rates in Egypt: The impact of maternal request.
Abstract In 1985, WHO experts found a rapid increase in caesarean section (CD) rates worldwide over the prior decade and concluded that there was no justification for any country to have a CD rate higher than 10-15% (WHO working group on caesarean section, Lancet,1985;2:436-7). PMID: 32920983 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 12, 2020 Category: OBGYN Authors: Hussein AM, Ramzy A, Jauniaux E Tags: BJOG Source Type: research

Early maternal Zika infection predicts severe neonatal neurological damage: results from the prospective Natural History of ZIKA Virus (ZIKV) Infection in Gestation (NATZIG) cohort study.
CONCLUSIONS: This prospective population-based study represents the largest Brazilian cohort study of ZIKV in pregnancy. Congenital anomalies potentially associated with CZS are less frequent than previously thought. There is a strong relationship between the gestational age of infection (≤11 weeks) and worse early infant prognosis. A notable proportion of apparently asymptomatic newborns can present with subclinical findings within three months of age. PMID: 32920998 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 12, 2020 Category: OBGYN Authors: Coutinho CM, de Moura Negrini SFB, de Almeida E Araujo DC, Teixeira SR, Amaral FR, Moro MCR, Fernandes JDCP, da Motta MSF, de Moura Negrini BV, Caldas CACT, Anastasio ART, Furtado JM, Bárbaro AAT, Yamamoto AY, Duarte G, Mussi-Pinhata MM, NATZIG cohort st Tags: BJOG Source Type: research

Chronic pelvic pain: importance of compatible clinical trial outcomes.
Abstract Chronic pelvic pain (CPP), often defined as non-cyclical pelvic pain lasting for 6 months or longer, affects approximately 2-24% of women, depending on the CPP definition used (Daniels et al. BMJ 2010;341:c4834). While CPP can be a symptom associated with a variety of health conditions (including endometriosis, irritable bowel syndrome, and interstitial cystitis), at least 30% of women undergoing laparoscopic surgery have no associated disease diagnosis or clear pathologic cause for their pain. PMID: 32920978 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 11, 2020 Category: OBGYN Authors: Shafrir AL Tags: BJOG Source Type: research

Extending the window for thrombolysis for treatment of acute ischemic stroke during pregnancy: a review.
Abstract Historically, safety of intravenous recombinant tissue plasminogen activator (IV rt-PA) for the treatment of acute ischemic stroke (AIS) is limited to use within 4.5 hours from symptom onset. Recent studies suggest the treatment window may be extended when patients have salvageable brain tissue on advanced neuroimaging. This paper describes a novel use of IV rt-PA for treatment of AIS in a pregnant patient within an extended-time window (>4.5 hours, and
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 11, 2020 Category: OBGYN Authors: Dinehart E, Leon Guerrero CR, Pham A, Chandra S, Petersen SM, Bathgate S, Ahmadzia HK Tags: BJOG Source Type: research

Re: Acupuncture for recurrent urinary tract infection in women: a systematic review and meta-analysis.
PMID: 32909671 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 9, 2020 Category: OBGYN Authors: Alraek T Tags: BJOG Source Type: research

Can risk prediction models help us individualise stillbirth prevention? A systematic review and critical appraisal of published risk models.
CONCLUSIONS: Almost all models identified were at high risk of bias. There are first trimester models of possible clinical benefit in early risk stratification; these require validation and clinical evaluation. There were few later pregnancy models, but if validated, these could be most relevant to individualised discussions around timing of birth. PMID: 32894620 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 6, 2020 Category: OBGYN Authors: Townsend R, Manji A, Allotey J, Heazell A, Jorgensen L, Magee LA, Mol BW, Snell K, Riley RD, Sandall J, Smith G, Patel M, Thilaganathan B, von Dadelszen P, Thangaratinam S, Khalil A Tags: BJOG Source Type: research

A RCT addressing the impact of delivery mode after asymptomatic obstetric anal sphincter injury.
t R Abstract An obstetric anal sphincter injury poses an important clinical dilemma for subsequent vaginal deliveries, which may be complicated by recurrent obstetric anal sphincter injury and / or worsening or de novo anal incontinence. PMID: 32894627 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 6, 2020 Category: OBGYN Authors: Tähtinen RM, Cartwright R Tags: BJOG Source Type: research

The impact of surgical learning curve on survival - reopening the door for minimally invasive surgery in the management of cervical cancer?
Abstract Minimally invasive surgery has been widely adopted in gynaecologic oncology with a significant surge the past decade associated with the introduction of robot-assisted surgery. Up until 2018, virtually all testimonials of minimally invasive surgery for cervical cancer indicated equal oncologic outcomes compared to laparotomy. The unexpected results from the only randomised controlled trial (Ramirez PT et al, N Engl J Med, 2018;379:1895-1904) seriously challenge the use of minimally invasive surgery for cervical cancer. PMID: 32894813 [PubMed - as supplied by publisher] (Source: BJOG : An Internationa...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 6, 2020 Category: OBGYN Authors: Falconer H Tags: BJOG Source Type: research

Attitudes towards risk-reducing salpingectomy: listen to the patients.
PMID: 32892497 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 5, 2020 Category: OBGYN Authors: Long Roche K Tags: BJOG Source Type: research

Effect of single- versus double-layer uterine closure during caesarean section on postmenstrual spotting (2Close): multicentre, double-blind, randomised controlled superiority trial.
Abstract OBJECTIVE: To evaluate if double-layer uterine closure after a first caesarean section (CS) is superior compared to single-layer uterine closure in terms of postmenstrual spotting and niche development in the uterine caesarean scar. DESIGN: Multicentre, double-blind, randomised controlled superiority trial SETTING: 32 hospitals in the Netherlands. POPULATION: 2292 women ≥ 18 years undergoing a first CS were randomly assigned (1:1). 1144 women were assigned to single-layer and 1148 to double-layer closure. METHODS: Single-layer unlocked closure and double-layer unlocked closure with the s...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Stegwee SI, van der Voet LF, Jornada Ben A, de Leeuw RA, van de Ven PM, Duijnhoven RG, Bongers MY, Lambalk CB, de Groot CJ, Huirne JA, 2Close study group Tags: BJOG Source Type: research

Extending provision of cell-free (cf)DNA screening for Down syndrome.
Abstract It is now 12 years since the discovery that fetal cfDNA fragments in maternal plasma can be used to detect Down syndrome. This single marker has a detection rate above 99% and a false-positive rate below 0.2%, a performance greatly exceeding conventional multiple serum and ultrasound marker screening tests. Nevertheless, there has not been widespread replacement of conventional screening by cfDNA. Commercial providers report annual cfDNA testing totaling millions but this covers only a few percent of pregnancies worldwide. PMID: 32892448 [PubMed - as supplied by publisher] (Source: BJOG : An Internat...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Cuckle HS Tags: BJOG Source Type: research

Tolerance of uncertainty: a unifying theme in pregnancy care.
Abstract High-risk obstetricians are accustomed to uncertainty-in fact, we have limited ability to predict the outcomes of even the most common clinical scenarios we encounter. For example: when will a short cervix lead to a periviable delivery? When will delivery occur following preterm premature rupture of membranes? Which macrosomic infants will experience a shoulder dystocia during vaginal birth? When will a term patient go into spontaneous labor? PMID: 32892454 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Gray KJ Tags: BJOG Source Type: research

Too close to call: Uterine closure technique at caesarean section.
Abstract As caesarean section rates around the world rise, attention has begun to turn to the impact of variations in surgical technique, particularly their effect on post-operative recovery and risk of future complications. A common surgical variation is either a single- or double-layer uterine closure. When assessing immediate and short-term outcomes both methods appear similarly effective (Dodd et al. Cochrane Database Syst Rev. 2014 Jul 22;(7):CD004732.). The analysis of longer-term sequelae for women following caesarean section may provide a more nuanced understanding of the impacts of varying surgical techni...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Walsh CR, Palmer KR Tags: BJOG Source Type: research

Ovarian cancer risk in Lynch syndrome: It's time to individualize.
Abstract Our understanding of cancer risks associated with Lynch syndrome (LS) has evolved since Dr. Warthin first identified family G in 1913. The current study by Ryan et al provides insight into provider and patient knowledge about gynecologic cancer care options in LS and found that counseling, surveillance, and risk reduction (RR) for these patients vary widely across providers in the UK (BJOG 2020 xxxx). The current study highlights two important points regarding care in LS. PMID: 32892474 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Ring KL Tags: BJOG Source Type: research

Aspirin should be targeted to those who need it.
Abstract Low dose aspirin, for the prevention of early onset pre-eclampsia is an established antenatal intervention; it is safe, effective, cheap and accessible in many health care settings. Optimal implementation strategies including dose, timing and screening are currently debated. The evidence supports starting aspirin early (before 16 weeks), prescribe at night, give up to 150mg and continue until at least 36 weeks gestation ((Poon et al. Int J Gynaecol Obstet. 2019 May;145 Suppl 1(Suppl 1):1-33). From the women's perspective, many may not be happy to routinely medicate an apparently normal pregnancy, to preve...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Green M, Shennan A Tags: BJOG Source Type: research

Is pretreatment with GnRH agonist necessary for endometrial preparation for frozen embryo transfer cycles in women with polycystic ovary syndrome?
Abstract First frozen embryo transfer (FET) in a freeze-only cycle strategy is the preferred option in high responders, such as women with polycystic ovarian syndrome (PCOS), undergoing assisted reproductive technologies (ART), since it enhances live birth rate, while reducing the chance of moderate/severe ovarian hyperstimulation syndrome (OHSS) compared with fresh transfer strategy (Bosdou et al. Hum Reprod 2019; 34:491-505). PMID: 32892512 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Bosdou JK, Anagnostis P, Kolibianakis EM Tags: BJOG Source Type: research

Association between chorionicity and preterm birth in twin pregnancies: A systematic review involving 29,864 twin pregnancies.
Abstract BACKGROUND: The perinatal mortality and morbidity among twins vary by chorionicity. Although it is considered that monochorionicity is associated with an increased risk of preterm birth in twin pregnancies, no systematic review exists evaluating this association. OBJECTIVE: This systematic review was undertaken to assess the association between preterm birth and chorionicity in twin pregnancies. SEARCH STRATEGY: We searched the electronic databases from January 1990 to July 2019 without language restrictions. SELECTION CRITERIA: All studies on twin pregnancies where chorionicity and preterm...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Marleen S, Dias C, Nandasena R, MacGregor R, Allotey J, Aquilina J, Khalil A, Thangaratinam S Tags: BJOG Source Type: research

Impact of changes to national UK Guidance on testing for gestational diabetes screening during a pandemic: a single centre observational study.
CONCLUSIONS: In our setting, The RCOG Covid-19 gestational diabetes screening regime failed to detect 47 of 82 (57%) women subsequently identified as gestational diabetics, and therefore cannot be recommended for general use. PMID: 32888369 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2020 Category: OBGYN Authors: Van De L'Isle Y, Steer PJ, Watt Coote I, Cauldwell M Tags: BJOG Source Type: research

Authors' reply re: Implementation of routine first-trimester combined screening for pre-eclampsia: a clinical effectiveness study.
cs and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 2, 2020 Category: OBGYN Authors: Authors' reply re: Implementation of routine first-trimester combined screening for pre-eclampsia: a clinical effectiveness study. Tags: BJOG Source Type: research

Re: Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial.
PMID: 32881374 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 1, 2020 Category: OBGYN Authors: Al-Inizi S Tags: BJOG Source Type: research

Re: Reflex cytology for triage of high-risk human papillomavirus positive self-sampled material in cervical cancer screening: a prospective cohort study.
PMID: 32869932 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - August 31, 2020 Category: OBGYN Authors: Song F, Yan P, Wu R Tags: BJOG Source Type: research