Lrp13a and Lrp13b serve as vitellogenin receptors in the ovary of zebrafish †
Biol Reprod. 2024 Apr 24:ioae040. doi: 10.1093/biolre/ioae040. Online ahead of print.ABSTRACTIn oviparous animals, egg yolk is largely derived from vitellogenin, which is taken up from the maternal circulation by the growing oocytes via the vitellogenin receptor. Recently, a novel member of the lipoprotein receptor superfamily termed low-density lipoprotein receptor-related protein 13 was identified and proposed as a candidate of vitellogenin receptor in oviparous animals. However, the roles of low-density lipoprotein receptor-related protein 13 in vitellogenesis are still poorly defined. Here, we investigated the expressi...
Source: Biology of Reproduction - April 25, 2024 Category: Reproduction Medicine Authors: Zhiquan Liu Nan Zhang Chuangxin Wang Lina Shi Yixuan Hu Yamei Wang Jianzhen Li Source Type: research
Factors defining developmental competence of bovine oocytes collected for in vitro embryo production
Biol Reprod. 2024 Apr 25:ioae065. doi: 10.1093/biolre/ioae065. Online ahead of print.ABSTRACTDespite the currently relatively low effectiveness of producing bovine embryos in vitro, there is a growing interest in applying this laboratory method in the field of reproduction. Many aspects of the procedure need to be improved. One of the main problems is the inferior developmental competence of in vitro matured oocytes that are collected using the ovum pick-up (OPU) method. The mechanisms of oocyte capacitation and maturation, as well as the in vivo conditions in which they grow and mature, should be carefully analyzed. A del...
Source: Biology of Reproduction - April 25, 2024 Category: Reproduction Medicine Authors: Aleksandra Teresa Pytel Krystyna Żyżyńska-Galeńska Zdzis ław Gajewski Krzysztof Papis Source Type: research
Viewing early life without labels: optical approaches for imaging the early embryo
Biol Reprod. 2024 Apr 22:ioae062. doi: 10.1093/biolre/ioae062. Online ahead of print.ABSTRACTEmbryo quality is an important determinant of successful implantation and a resultant live birth. Current clinical approaches for evaluating embryo quality rely on subjective morphology assessments or an invasive biopsy for genetic testing. However, both approaches can be inherently inaccurate and crucially, fail to improve the live birth rate following the transfer of in vitro produced embryos. Optical imaging offers a potential non-invasive and accurate avenue for assessing embryo viability. Recent advances in various label-free ...
Source: Biology of Reproduction - April 22, 2024 Category: Reproduction Medicine Authors: Darren J X Chow Tiffany C Y Tan Avinash Upadhya Megan Lim Kishan Dholakia Kylie R Dunning Source Type: research
HMGB1 regulates autophagy of placental trophoblast through ERK signaling pathway
CONCLUSIONS: HMGB1 participates in the regulation of autophagy through the ERK signaling pathway and affects placental development.PMID:38647664 | DOI:10.1093/biolre/ioae064 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 22, 2024 Category: Reproduction Medicine Authors: Ming-Rui Li En-Xiang Chen Zhuo-Hang Li Hong-Lan Song Yi Zhang Fang-Fang Li You-Long Xie Jing Tang Yu-Bin Ding Li-Juan Fu Source Type: research
Viewing early life without labels: optical approaches for imaging the early embryo
Biol Reprod. 2024 Apr 22:ioae062. doi: 10.1093/biolre/ioae062. Online ahead of print.ABSTRACTEmbryo quality is an important determinant of successful implantation and a resultant live birth. Current clinical approaches for evaluating embryo quality rely on subjective morphology assessments or an invasive biopsy for genetic testing. However, both approaches can be inherently inaccurate and crucially, fail to improve the live birth rate following the transfer of in vitro produced embryos. Optical imaging offers a potential non-invasive and accurate avenue for assessing embryo viability. Recent advances in various label-free ...
Source: Biology of Reproduction - April 22, 2024 Category: Reproduction Medicine Authors: Darren J X Chow Tiffany C Y Tan Avinash Upadhya Megan Lim Kishan Dholakia Kylie R Dunning Source Type: research
HMGB1 regulates autophagy of placental trophoblast through ERK signaling pathway
CONCLUSIONS: HMGB1 participates in the regulation of autophagy through the ERK signaling pathway and affects placental development.PMID:38647664 | DOI:10.1093/biolre/ioae064 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 22, 2024 Category: Reproduction Medicine Authors: Ming-Rui Li En-Xiang Chen Zhuo-Hang Li Hong-Lan Song Yi Zhang Fang-Fang Li You-Long Xie Jing Tang Yu-Bin Ding Li-Juan Fu Source Type: research
Biomarker-based human and animal sperm phenotyping: the good, the bad and the ugly
Biol Reprod. 2024 Apr 19:ioae061. doi: 10.1093/biolre/ioae061. Online ahead of print.ABSTRACTConventional, brightfield-microscopic semen analysis provides important baseline information about sperm quality of an individual; however, it falls short of identifying subtle subcellular and molecular defects in cohorts of "bad", defective human and animal spermatozoa with seemingly normal phenotypes. To bridge this gap, it is desirable to increase the precision of andrological evaluation in humans and livestock animals by pursuing advanced biomarker-based imaging methods. This review, spiced up with occasional classic movie refe...
Source: Biology of Reproduction - April 19, 2024 Category: Reproduction Medicine Authors: Peter Sutovsky Lauren E Hamilton Michal Zigo Mayra E Ortiz D'Avila Assump ção Alexis Jones Filip Tirpak Yuksel Agca Karl Kerns Miriam Sutovsky Source Type: research
Structural analysis of the female reptile reproductive system by micro-computed tomography and optical coherence tomography †
This study represents the first time that microCT has been used to study all reproductive organs in this species and the very first time that OCT has been applied to this species. We show how the non-destructive volumetric imaging provided by each modality reveals anatomical context including orientation and relationships between reproductive organs of the anole lizard. In addition to broad patterns of morphology, both imaging modalities provide the high resolution necessary to capture details and key anatomical features of each organ. We demonstrate that classic histological features can be appreciated within whole-organ ...
Source: Biology of Reproduction - April 19, 2024 Category: Reproduction Medicine Authors: Bonnie K Kircher Michaela A McCown Deirdre M Scully Richard R Behringer Irina V Larina Source Type: research
Microwave-assisted dehydration, long-term storage at non-freezing temperatures, and rehydration of cat germinal vesicles
Biol Reprod. 2024 Apr 18:ioae060. doi: 10.1093/biolre/ioae060. Online ahead of print.ABSTRACTGerminal vesicles (GVs) are alternative targets for female fertility preservation due to their availability and high resilience against non-physiological conditions. Preserved GVs can then be transferred to fresh cytoplasts to reconstitute viable oocytes. Here, we describe a GV preservation method that employs non-ionizing microwave radiations imparting energy to water molecules, which results in rapid and homogeneous drying of the sample. Trehalose is added as a xero-protectant before the radiations, enabling isothermal vitrificat...
Source: Biology of Reproduction - April 18, 2024 Category: Reproduction Medicine Authors: Pei-Chih Lee Pierre Comizzoli Source Type: research
30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research
Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research
30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research
Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research
Trajectory of primordial follicle depletion is accelerated in obese mice in response to 7,12-dimethylbenz[a]anthracene exposure
This study indicates that obesity influences ovotoxicity caused by a genotoxicant, potentially involving accelerated primordial follicle activation and hampering normal follicular dynamics.PMID:38625059 | DOI:10.1093/biolre/ioae059 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 16, 2024 Category: Reproduction Medicine Authors: Jaspreet K Rishi Kelsey Timme Hunter E White Karl C Kerns Aileen F Keating Source Type: research
Trajectory of primordial follicle depletion is accelerated in obese mice in response to 7,12-dimethylbenz[a]anthracene exposure
This study indicates that obesity influences ovotoxicity caused by a genotoxicant, potentially involving accelerated primordial follicle activation and hampering normal follicular dynamics.PMID:38625059 | DOI:10.1093/biolre/ioae059 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 16, 2024 Category: Reproduction Medicine Authors: Jaspreet K Rishi Kelsey Timme Hunter E White Karl C Kerns Aileen F Keating Source Type: research
