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Ovarian sex steroid and epithelial control of immune responses in the uterus and oviduct: human and animal models
This article will discuss how ovarian sex steroids affect the immune reactions elicited by the epithelial cells of the non-pregnant uterus and oviduct in the bovine, murine, and human species.PMID:38038990 | DOI:10.1093/biolre/ioad166 (Source: Biology of Reproduction)
Source: Biology of Reproduction - December 1, 2023 Category: Reproduction Medicine Authors: Rasoul Kowsar Khaled Sadeghi Farzad Hashemzadeh Akio Miyamoto Source Type: research

Correction to: The effects of heat stress on intrauterine development, reproductive function, and ovarian gene expression of F1 female mice as well as gene expression of F2 embryos
Biol Reprod. 2023 Nov 29:ioad163. doi: 10.1093/biolre/ioad163. Online ahead of print.NO ABSTRACTPMID:38031241 | DOI:10.1093/biolre/ioad163 (Source: Biology of Reproduction)
Source: Biology of Reproduction - November 30, 2023 Category: Reproduction Medicine Source Type: research

AHCY plays multiple roles in maintaining the identity and pluripotency of mouse embryonic stem cells
Biol Reprod. 2023 Nov 30:ioad165. doi: 10.1093/biolre/ioad165. Online ahead of print.ABSTRACTAdenosylhomocysteinase (AHCY), a key enzyme in the methionine cycle, is essential for the development of embryos and the maintenance of mESCs. However, the precise underlying mechanism of Ahcy in regulating pluripotency remains unclear. As the only enzyme that can hydrolyze S-adenosylhomocysteine in mammals, AHCY plays a critical role in the metabolic homeostasis, epigenetic remodeling, and transcriptional regulation. Here, we identified Ahcy as a direct target of OCT4 and unveiled that AHCY regulates the self-renewal and different...
Source: Biology of Reproduction - November 30, 2023 Category: Reproduction Medicine Authors: Qi Jiang Shubing Lan Fancheng Tan Yiping Liang Zhencheng Guo Yanlin Hou Hui Zhang Guangming Wu Zhonghua Liu Source Type: research

EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signalling
In conclusion, we demonstrated that abnormally high expression of EHD1 in endometrial stromal cells attenuated the activity of PRB associated with progesterone resistance in a subset of women with RIF.PMID:38011671 | DOI:10.1093/biolre/ioad161 (Source: Biology of Reproduction)
Source: Biology of Reproduction - November 27, 2023 Category: Reproduction Medicine Authors: Hui Zhang Liping Kong Zhiwen Cao Yinchun Zhu Yue Jiang Xiaoying Wang Ruiwei Jiang Yang Liu Jidong Zhou Yu Kang Xin Zhen Na Kong Min Wu Guijun Yan Haixiang Sun Source Type: research

Evaluation of novel biomarkers for early pregnancy outcome prediction
CONCLUSION: Performance of commercially available ELISAs was acceptable for a panel of novel biomarkers to predict early pregnancy outcome. Of these, six and seven candidates demonstrated good discriminatory capacity of pregnancy location and viability, respectively, when validated in a distinct external population. Four markers demonstrated good discrimination for both location and viability.PMID:38011676 | DOI:10.1093/biolre/ioad162 (Source: Biology of Reproduction)
Source: Biology of Reproduction - November 27, 2023 Category: Reproduction Medicine Authors: Kassie J Bollig Suneeta Senapati Peter Takacs Jared C Robins Daniel J Haisenleder Lynn A Beer David W Speicher Nathanael C Koelper Kurt T Barnhart Source Type: research