Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand.
Abstract INTRODUCTION: Paracetamol is a common agent taken in deliberate self-poisoning and in accidental overdose in adults and children. Paracetamol poisoning is the commonest cause of severe acute liver injury. Since the publication of the previous guidelines in 2015, several studies have changed practice. A working group of experts in the area, with representation from all Poisons Information Centres of Australia and New Zealand, were brought together to produce an updated evidence-based guidance. MAIN RECOMMENDATIONS (UNCHANGED FROM PREVIOUS GUIDELINES): The optimal management of most patients with parac...
Source: Med J Aust - December 1, 2019 Category: General Medicine Authors: Chiew AL, Reith D, Pomerleau A, Wong A, Isoardi KZ, Soderstrom J, Buckley NA Tags: Med J Aust Source Type: research

Pre-school child blood lead levels in a population-derived Australian birth cohort: the Barwon Infant Study.
CONCLUSION: Blood lead levels in our pre-school children were lower than in previous Australian surveys and recent surveys in areas at risk of higher exposure, and no children had levels above 5 μg/dL. Our findings support advice to manage risks related to exposure to historical lead, especially in older houses. PMID: 31760661 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 24, 2019 Category: General Medicine Authors: Symeonides C, Vuillermin P, Sly PD, Collier F, Lynch V, Falconer S, Pezic A, Wardrop N, Dwyer T, Ranganathan S, Ponsonby AB Tags: Med J Aust Source Type: research

Sex and gender in health research: updating policy to reflect evidence.
PMID: 31760662 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 24, 2019 Category: General Medicine Authors: Sex and Gender Sensitive Research Call to Action Group Tags: Med J Aust Source Type: research

Australian Health Research Alliance: national priorities in data-driven health care improvement.
PMID: 31733072 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 16, 2019 Category: General Medicine Authors: Teede HJ, Johnson A, Buttery J, Jones CA, Boyle DI, Jennings GL, Shaw T Tags: Med J Aust Source Type: research

Essential oil exposures in Australia: analysis of cases reported to the NSW Poisons Information Centre.
PMID: 31709543 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 10, 2019 Category: General Medicine Authors: Lee KA, Harnett JE, Cairns R Tags: Med J Aust Source Type: research

Validating Indigenous status in a regional Queensland hospital emergency department dataset with patient-linked data.
PMID: 31709545 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 10, 2019 Category: General Medicine Authors: O'Loughlin M, Harriss L, Mills J, Thompson F, McDermott R Tags: Med J Aust Source Type: research

Rescheduling codeine-containing analgesics reduced codeine-related hospital presentations.
PMID: 31709546 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 10, 2019 Category: General Medicine Authors: Harris K, Jiang A, Knoeckel R, Isoardi KZ Tags: Med J Aust Source Type: research

Should we routinely test for Mycoplasma genitalium when testing for other sexually transmitted infections?
PMID: 31709549 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - November 10, 2019 Category: General Medicine Authors: Stewart JD, Webb B, Francis M, Graham M, Korman TM Tags: Med J Aust Source Type: research

Management of pregabalin and gabapentin prescribing and use in NSW prisons.
PMID: 31674028 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 31, 2019 Category: General Medicine Authors: Nicholls G, Samios P, Hampton S Tags: Med J Aust Source Type: research

Inpatient diabetes care requires adequate support, not just HbA1c screening.
PMID: 31674035 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 31, 2019 Category: General Medicine Authors: Hare MJ, Shaw JE Tags: Med J Aust Source Type: research

Medical abortion: it is time to lift restrictions.
PMID: 31625137 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: de Costa CM, Black KI, Russell DB Tags: Med J Aust Source Type: research

Nationally linked data to improve health services and policy.
PMID: 31625139 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: Briffa TG, Jorm L, Jackson RT, Reid C, Chew DP Tags: Med J Aust Source Type: research

Medical abortion: it is time to lift restrictions.
PMID: 31625140 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: de Moel-Mandel C, Graham M Tags: Med J Aust Source Type: research

Histiocytoid Sweet syndrome.
PMID: 31625142 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: Wark KJ, Crawshaw H Tags: Med J Aust Source Type: research

Orbital rhabdomyosarcoma: a rare ophthalmic condition.
PMID: 31625156 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: Kim J, Ussher JG Tags: Med J Aust Source Type: research

Increasing illicit use of nitrous oxide in presentations to NSW emergency departments.
PMID: 31625166 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: Bethmont A, Harper CE, Chan BS, Dawson AH, McAnulty J Tags: Med J Aust Source Type: research

Vitamin B12 supplementation futile for preventing demyelination in ongoing nitrous oxide misuse.
PMID: 31625167 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - October 17, 2019 Category: General Medicine Authors: Blair C, Tremonti C, Edwards L, Haber PS, Halmagyi GM Tags: Med J Aust Source Type: research

Perioperative considerations in the management of obstructive sleep apnoea.
Abstract Obstructive sleep apnoea (OSA) is characterised by repetitive compromise of the upper airway, causing impaired ventilation, sleep fragmentation, and daytime functional impairment. It is a heterogeneous condition encompassing different phenotypes. The prevalence of OSA among patients presenting for elective surgery is growing, largely attributable to an increase in age and obesity rates, and most patients remain undiagnosed and untreated at the time of surgery. This condition is an established risk factor for increased perioperative cardiopulmonary morbidity, heightened in the presence of concurrent medica...
Source: Med J Aust - September 15, 2019 Category: General Medicine Authors: Holt NR, Downey G, Naughton MT Tags: Med J Aust Source Type: research

Record number of influenza tests in 2019, not a "mutant flu crisis".
Record number of influenza tests in 2019, not a "mutant flu crisis". Med J Aust. 2019 Sep 08;: Authors: Sheppeard V, Gilmour R, Tobin S PMID: 31494936 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - September 8, 2019 Category: General Medicine Authors: Sheppeard V, Gilmour R, Tobin S Tags: Med J Aust Source Type: research

Regulating voluntary assisted dying in Australia: some insights from the Netherlands.
PMID: 31494938 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - September 8, 2019 Category: General Medicine Authors: Onwuteaka-Philipsen B, Willmott L, White BP Tags: Med J Aust Source Type: research

Concussion risk and suicide prevention: balancing the risks and benefits of youth sport.
PMID: 31473997 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - September 1, 2019 Category: General Medicine Authors: Clacy A, Hermens DF, Broadhouse K, Lagopoulos J Tags: Med J Aust Source Type: research

Calendar of conferences in Australia and New Zealand.
PMID: 31474005 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - September 1, 2019 Category: General Medicine Authors: Swannell C Tags: Med J Aust Source Type: research

News briefs.
PMID: 31474006 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - September 1, 2019 Category: General Medicine Authors: Swannell C Tags: Med J Aust Source Type: research

Pilot trial of digital breast tomosynthesis (3D mammography) for population-based screening in BreastScreen Victoria.
CONCLUSIONS: Breast cancer detection, recall for assessment, and screen reading time were each higher for tomosynthesis than for standard mammography. Our preliminary findings could form the basis of a large scale comparative evaluation of tomosynthesis and standard mammography for breast screening in Australia. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry, ACTRN12617000947303. PMID: 31448816 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 26, 2019 Category: General Medicine Authors: Houssami N, Lockie D, Clemson M, Pridmore V, Taylor D, Marr G, Evans J, Macaskill P Tags: Med J Aust Source Type: research

Selecting and optimising patients for total knee arthroplasty.
PMID: 31420864 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Miles LF, Burbury KL, Story DA Tags: Med J Aust Source Type: research

Paracetamol overdose: limiting the potential for harm.
PMID: 31420865 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Graudins A, Wong A Tags: Med J Aust Source Type: research

Clinically important sport-related traumatic brain injuries in children.
PMID: 31420871 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Eapen N, Davis GA, Borland ML, Phillips N, Oakley E, Hearps S, Kochar A, Dalton S, Cheek J, Furyk J, Lyttle MD, Bressan S, Crowe L, Dalziel S, Tavender E, Babl FE Tags: Med J Aust Source Type: research

The financial cost of intensive care in Australia: a multicentre registry study.
PMID: 31420872 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Hicks P, Huckson S, Fenney E, Leggett I, Pilcher D, Litton E Tags: Med J Aust Source Type: research

Pulmonary tumour thrombotic microangiopathy: a rare but underappreciated complication of malignancy.
PMID: 31420874 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Siriratnam P, Boolell V Tags: Med J Aust Source Type: research

Diabetic ketoacidosis with sodium-glucose cotransporter type 2 inhibitors: a case series.
PMID: 31420875 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: McLachlan G, Keith C, Frauman A Tags: Med J Aust Source Type: research

Pulmonary challenges of prolonged journeys to space: taking your lungs to the moon.
Abstract Space flight presents a set of physiological challenges to the space explorer which result from the absence of gravity (or in the case of planetary exploration, partial gravity), radiation exposure, isolation and a prolonged period in a confined environment, distance from Earth, the need to venture outside in the hostile environment of the destination, and numerous other factors. Gravity affects regional lung function, and the human lung shows considerable alteration in function in low gravity; however, this alteration does not result in deleterious changes that compromise lung function upon return to Ear...
Source: Med J Aust - August 16, 2019 Category: General Medicine Authors: Prisk GK Tags: Med J Aust Source Type: research

Disrupting medical publishing and the future of medical journals: a personal view.
PMID: 31422578 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - August 1, 2019 Category: General Medicine Authors: Gee CE, Talley Ac NJ Tags: Med J Aust Source Type: research

The future of academic publishing: disruption, opportunity and a new ecosystem.
PMID: 31422580 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - August 1, 2019 Category: General Medicine Authors: Barbour V Tags: Med J Aust Source Type: research

Calendar of conferences in Australia and New Zealand.
PMID: 31422581 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - August 1, 2019 Category: General Medicine Authors: Swannell C Tags: Med J Aust Source Type: research

Integrating palliative care and symptom relief into responses to humanitarian crises.
PMID: 31373022 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - August 1, 2019 Category: General Medicine Authors: Krakauer EL, Daubman BR, Aloudat T Tags: Med J Aust Source Type: research

Aeromedical retrievals of people for mental health care and the low level of clinical support in rural and remote Australia.
CONCLUSION: Mental and behavioural disorders are an important problem in rural and remote communities, and acute presentations trigger a considerable number of RFDS retrievals. PMID: 31347169 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - July 25, 2019 Category: General Medicine Authors: Gardiner FW, Coleman M, Teoh N, Harwood A, Coffee NT, Gale L, Bishop L, Laverty M Tags: Med J Aust Source Type: research

Australia's response to the global threat of antimicrobial resistance: past, present and future.
PMID: 31313300 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - July 16, 2019 Category: General Medicine Authors: Davis JS, Jones CA, Cheng AC, Howden BP Tags: Med J Aust Source Type: research

Four ACs for medical elite.
PMID: 31256438 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - July 1, 2019 Category: General Medicine Authors: Swannell C Tags: Med J Aust Source Type: research

Getting it Right: validating a culturally specific screening tool for depression (aPHQ-9) in Aboriginal and Torres Strait Islander Australians.
CONCLUSIONS: Indigenous Australians found the aPHQ-9 acceptable as a screening tool for depression. Applying a cut-point of 10 points, the performance characteristics of the aPHQ were good. PMID: 31256439 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - July 1, 2019 Category: General Medicine Authors: Getting it Right Collaborative Group Tags: Med J Aust Source Type: research

News briefs.
PMID: 31256440 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - July 1, 2019 Category: General Medicine Authors: Swannell C Tags: Med J Aust Source Type: research

Pharmaceutical Benefits Scheme restrictions on anti-epileptic drug prescribing promote unsafe and outdated practice.
PMID: 31256431 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 30, 2019 Category: General Medicine Authors: Gericke CA, O'Brien TJ Tags: Med J Aust Source Type: research

Polypharmacy among older Australians, 2006-2017: a population-based study.
CONCLUSIONS: The prevalence of polypharmacy among older Australians is relatively high, affecting almost one million older people, and the number is increasing as the population ages. Our estimates are probably low, as we could not take over-the-counter or complementary medicines or private prescriptions into account. Polypharmacy can be appropriate, but there is substantial evidence for its potential harm and the importance of rationalising unnecessary medicines, particularly in older people. PMID: 31219179 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 20, 2019 Category: General Medicine Authors: Page AT, Falster MO, Litchfield M, Pearson SA, Etherton-Beer C Tags: Med J Aust Source Type: research

Updates and advances in the treatment of Parkinson disease.
Abstract Parkinson disease (PD) is a complex neurodegenerative disorder that can present heterogeneously with a combination of motor and non-motor symptoms. α-synuclein, a neuronal protein, can undergo aberrant conformational change resulting in the intra-neuronal accumulation of toxic oligomers that form Lewy bodies, the pathological hallmark of PD. There is evidence that pathological α-synuclein exhibits prion-like behaviour in its mode of transmission through the nervous system. The choice of initial dopaminergic treatments should be individually tailored but long term outcomes appear to be equivale...
Source: Med J Aust - June 16, 2019 Category: General Medicine Authors: Hayes MW, Fung VS, Kimber TE, O'Sullivan JD Tags: Med J Aust Source Type: research

Acute kidney injury in Indigenous Australians: an unrecognised priority for action.
PMID: 31179541 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 10, 2019 Category: General Medicine Authors: Cass A, Hughes JT Tags: Med J Aust Source Type: research

Flinders medical students pilot free clinic for homeless men.
PMID: 31179542 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 9, 2019 Category: General Medicine Authors: Phua AI, Parry YK Tags: Med J Aust Source Type: research

HPV vaccination coverage and course completion rates for Indigenous Australian adolescents, 2015.
CONCLUSION: HPV vaccine coverage is high, but course completion is generally lower for Indigenous adolescents. Strategies for improving completion rates for Indigenous Australians are needed to end the higher burden of cervical cancer among Indigenous than non-Indigenous women. PMID: 31179546 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 9, 2019 Category: General Medicine Authors: Brotherton JM, Winch KL, Chappell G, Banks C, Meijer D, Ennis S, Peterson K, Webby R, Whop LJ Tags: Med J Aust Source Type: research

Time to stop flogging a dead horse?
PMID: 31155719 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 3, 2019 Category: General Medicine Authors: Canuto K Tags: Med J Aust Source Type: research

An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care.
PMID: 31155725 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 3, 2019 Category: General Medicine Authors: Bowen AC, Daveson K, Anderson L, Tong SY Tags: Med J Aust Source Type: research

Inclusion of Indigenous Australians in biobanks: a step to reducing inequity in health care.
PMID: 31155726 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 3, 2019 Category: General Medicine Authors: Elsum I, McEwan C, Kowal EE, Cadet-James Y, Kelaher M, Woodward L Tags: Med J Aust Source Type: research

Identifying the cultural heritage of patients during clinical handover and in hospital medical records.
PMID: 31155718 [PubMed - as supplied by publisher] (Source: Med J Aust)
Source: Med J Aust - June 2, 2019 Category: General Medicine Authors: Welch SA, Robinson S, Langley T, Deweerd P Tags: Med J Aust Source Type: research