Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production
ConclusionsThese results suggest that liveS. salivarius or its cell-free supernatant significantly ameliorated the disruption of epithelial tight junctions induced byP. melaninogenica, likely through the inhibition ofP. melaninogenica growth mediated by metabolic acid production. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 1, 2024 Category: Microbiology Authors: Pingyi Zhu,
Ruru Shao,
Pan Xu,
Ruowen Zhao,
Chen Zhao,
Jian Fei,
Yuan He Tags: ORIGINAL ARTICLE Source Type: research
Research in brief: How prevalent is rough sex? Results from a national online sample of adults in Germany
DiscussionResults show that rough sex is common. Sexual health professionals, educators, and researchers should be prepared to guide current and aspiring practitioners of rough sex, helping them understand potential benefits, risks, and age- and gender-related differences. (Source: Perspectives on Sexual and Reproductive Health)
Source: Perspectives on Sexual and Reproductive Health - May 1, 2024 Category: Sexual Medicine Authors: Nicola D öring,
M. Rohangis Mohseni,
Laura Pietras,
Arne Dekker,
Peer Briken Tags: RESEARCH IN BRIEF Source Type: research
Evaluating the development of endometriosis and adenomyosis lesions over time: An ultrasound study of symptomatic women
ConclusionsOur findings suggest that in symptomatic women, endometriosis and adenomyosis lesions visible at ultrasound may develop over time. However, majority of women remain having normal ultrasound examinations despite symptoms. Exacerbation of dysmenorrhea or chronic pelvic pain during follow-up was not associated with the development of endometriosis or adenomyosis lesions visible at ultrasound, suggesting that even women with less severe symptoms might benefit from a follow-up ultrasound when indicated. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 1, 2024 Category: OBGYN Authors: Sofie Orlov,
Povilas Sladkevicius,
Ligita Jokubkiene Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Listening to Black Women's Perspectives of Birth Centers and Midwifery Care: Advocacy, Protection, and Empowerment
DiscussionThe Black women interviewed in this study emphasized the prevalence of racism and discrimination in perinatal health care encounters, a reflection consistent with current literature. Black women also expressed a desire to use birth centers and midwifery care but identified the barriers in Texas that impede access. Study findings highlight the need to address barriers to promote equitable perinatal health care access for Black women. (Source: Journal of Midwifery and Women's Health)
Source: Journal of Midwifery and Women's Health - May 1, 2024 Category: Midwifery Authors: Shalom Anyiam,
Jennifer Woo,
Becky Spencer Tags: RESEARCH ARTICLE Source Type: research
Symmetrical cutaneous rash in two women
Key Clinical MessageSymmetrical drug-related intertriginous and flexural exanthema, commonly known as “baboon syndrome” due to its typical involvement of the gluteal area, is an erythematous symmetrical rash associated with systemic drug administration. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 1, 2024 Category: General Medicine Authors: Gionathan Orioni,
Maria Camila Velez ‐Pelaez,
Michela V. R. Starace,
Vera Tengattini,
Emanuel Raschi,
Michelangelo La Placa Tags: CASE IMAGE Source Type: research
Trends in infectious spondylitis from 2000 to 2020
ConclusionRecently, infections caused by indigenous bacteria in the oral cavity and intestines have increased more than those caused by resistant bacteria over the past two decade. (Source: European Spine Journal)
Source: European Spine Journal - May 1, 2024 Category: Orthopaedics Source Type: research
Fracture Risk and Health Profiles Differ According to Relationship Status: Findings from the Hertfordshire Cohort Study
AbstractRegistry studies have suggested associations between relationship status and fracture risk. We considered associations between relationship status and incident fracture in the Hertfordshire Cohort Study, comprising community-dwelling older adults, and explored associations between socioeconomic and lifestyle factors with relationship status. 2997 participants completed a baseline questionnaire (1998 –2004) and clinic visit. Participants were followed up until December 2018 using Hospital Episode Statistics, which report clinical outcomes using codes from the 10th revision of the International Classification of Di...
Source: Calcified Tissue International - May 1, 2024 Category: Orthopaedics Source Type: research
Treatment planning and delivery practice of lung SBRT: Results of the 2022 ESTRO physics survey
Lung cancer is the second most commonly diagnosed cancer worldwide and is the leading cause of cancer death for both men and women [1]. Surgery is the standard treatment for early-stage non-small cell lung cancer (NSCLC), the most common type of lung cancer, with five-year survival rates of around 70% [2]. However, many patients are unsuitable for surgery [2] or decline surgery [3] and therefore alternative options for these patients are needed. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - May 1, 2024 Category: Radiology Authors: Antony Carver, Alessandro Scaggion, Diego Jurado-Bruggeman, Oliver Blanck, Emmy Dalqvist, Francesca Romana Giglioli, Aljasa Jenko, Kristin Karlsson, Vanya Staykova, Ans Swinnnen, Samantha Warren, Pietro Mancosu, Nuria Jornet Tags: Original Article Source Type: research
Unlocking the power of synergy: High-intensity functional training and early time-restricted eating for transformative changes in body composition and cardiometabolic health in inactive women with obesity
by Ranya Ameur, Rami Maaloul, S émah Tagougui, Fadoua Neffati, Faten Hadj Kacem, Mohamed Fadhel Najjar, Achraf Ammar, Omar Hammouda
ObjectiveThe purpose of this study was to examine the long-term effects of time-restricted eating (TRE), with or without high intensity functional training (HIFT), on body composition and cardiometabolic biomarkers among inactive women with obesity. MethodsSixty-four women (BMI = 35.03 ± 3.8 kg/m2; age = 32.1 ± 10 years) were randomly allocated to either: (1) TRE (≤8-h daily eating window, with ad libitum energy intake) group; (2) HIFT (3 sessions/week) group; or (3) TRE combined with HIF...
Source: PLoS One - May 1, 2024 Category: Biomedical Science Authors: Ranya Ameur Source Type: research
Does the use of bisphosphonates during pregnancy affect fetal outcomes? A systematic review
ConclusionAlthough previous reports have linked BPs before or during pregnancy with adverse neonatal outcomes, these associations should be interpreted with caution. Given the complexity of these findings, further research is necessary to provide more definitive insights to guide clinical decisions regarding the use of BPs in pregnant women. (Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - May 1, 2024 Category: Drugs & Pharmacology Source Type: research
Response to the Letter to the Editor by Jorge Violante-Cumpa; Marina Norde & amp; Geloneze Geloneze “Fat-free mass index is a feasible predictor of insulin resistance in women with polycystic ovary syndrome: evidence from a cross-sectional study”
(Source: Endocrine)
Source: Endocrine - May 1, 2024 Category: Endocrinology Source Type: research
Alterations of cardiometabolic risk profile in polycystic ovary syndrome: 13 years follow-up in an unselected population
ConclusionsAging women with PCOS in the population have higher androgen levels and similar cardiometabolic risk profile compared to age- and BMI-matched healthy women. Epicardial fat thickness, a marker of cardiometabolic risk, appear to be associated with hyperandrogenism. Further research is needed on larger community-based cohorts where older patients are assessed with a longer follow-up. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 1, 2024 Category: Endocrinology Source Type: research
Risks of suboptimal and excessive thyroid hormone replacement across ages
ConclusionSuboptimal and excessive LT4 replacement of the preventable non-communicable disease hypothyroidism requires more focus from the healthcare system and from the global political systems to prevent the personally devastating and socioeconomically challenging consequences. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 1, 2024 Category: Endocrinology Source Type: research
Does gestational diabetes mellitus increase the risk of cardiovascular disease? A Mendelian randomization study
ConclusionWomen with a prior history of GDM face an elevated risk of future CAD. This increased risk of CAD cannot be solely attributed to the subsequent onset of diabetes. Regular CAD risk assessment and primary prevention strategies are of paramount importance for women with a history of GDM. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 1, 2024 Category: Endocrinology Source Type: research
Cost-effectiveness of pessary therapy versus surgery for symptomatic pelvic organ prolapse: an economic evaluation alongside a randomised non-inferiority controlled trial
Conclusions
Non-inferiority of pessary therapy regarding the PGI-I could not be shown and no statistically significant differences in QALYs between interventions were found. Due to significantly lower costs, pessary therapy is likely to be cost-effective compared with surgery as an initial treatment option for women with symptomatic POP treated in secondary care.
Trial registration number
NTR4883. (Source: BMJ Open)
Source: BMJ Open - May 1, 2024 Category: General Medicine Authors: Ben, A. J., van der Vaart, L. R., E. Bosmans, J., Roovers, J.-P. W. R., Lagro-Janssen, A. L. M., van der Vaart, C. H., Vollebregt, A., PEOPLE group, Milani, Bon, Bongers, Bos, Broekman, Dietz, van Eijndhoven, Hakvoort, Janszen, Kluivers, Link, Massop-Helm Tags: Open access, Health economics Source Type: research
