A prognostic system for epithelial ovarian carcinomas using machine learning
ConclusionsEACCD was successfully applied to integrate A and H with T, N, and M for stratification and survival prediction of epithelial ovarian carcinoma patients. Additional factors could be advantageously incorporated to test the prognostic impact of emerging diagnostic or therapeutic advances. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 5, 2021 Category: OBGYN Authors: Philip M. Grimley, Zhenqiu Liu, Kathleen M. Darcy, Matthew T. Hueman, Huan Wang, Li Sheng, Donald E. Henson, Dechang Chen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Antenatal prediction models for short ‐ and medium‐term outcomes in preterm infants
ABSTRACTIntroductionIn extremely and very preterm infants, predicting individual risks for adverse outcomes antenatally is challenging but necessary for risk ‐stratified perinatal management and parents’ participation in decision making about treatment. Our aim was to develop and validate prediction models for short‐term (neonatal period) and medium‐term (3 years of age) outcomes based on antenatal maternal and fetal factors alone.Material and methodsA population ‐based study was conducted on 31,157 neonates weighing ≤1,500 g and born between 22 and 31 weeks of gestation registered in the Neonatal Research...
Source: Acta Obstetricia et Gynecologica Scandinavica - March 3, 2021 Category: OBGYN Authors: Takafumi Ushida, Yoshinori Moriyama, Masahiro Nakatochi, Yumiko Kobayashi, Kenji Imai, Tomoko Nakano ‐Kobayashi, Noriyuki Nakamura, Masahiro Hayakawa, Hiroaki Kajiyama, Tomomi Kotani, The Neonatal Research Network of Japan Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Induction of labor in breech ‐presenting fetuses
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 27, 2021 Category: OBGYN Authors: Johanne Augusta Horn Welle ‐Strand, Christian Tappert, Torbjørn Moe Eggebø Tags: LETTER TO THE EDITOR Source Type: research

Vaginal suture/knot exposure following laparoscopic sacral colpo/cervicopexy
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 27, 2021 Category: OBGYN Authors: Audrey Tsilanizara, Xavier Deffieux Tags: LETTER TO THE EDITOR Source Type: research

Thirty years of mirena: A story of innovation and change in women ’s healthcare
AbstractSince its introduction in 1990, the levonorgestrel ‐releasing intrauterine system (LNG‐IUS) has played a key role in shaping the healthcare landscape of women. Here we explore the development of the first LNG‐IUS (Mirena®) and the early clinical trials that demonstrated its potential. We highlight the contraceptive and therapeutic benefits of Mirena®, and discuss how clinical practice has been changed since the introduction of LNG‐IUS and other long‐acting reversible contraceptive methods. The history of Mirena® is rich in innovation and has also paved the way to the development of smaller int...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 24, 2021 Category: OBGYN Authors: Kristina Gemzell ‐Danielsson, Ali Kubba, Cecilia Caetano, Thomas Faustmann, Eeva Lukkari‐Lax, Oskari Heikinheimo Tags: COMMENTARY Source Type: research

Chronic hypertension in pregnancy stratified by first trimester blood pressure control and adverse perinatal outcomes: a prospective observational study
AbstractIntroductionThe aim of this study was to assess perinatal outcomes in women with chronic hypertension (CH) stratified into four groups according to their blood pressure (BP) control in the first trimester of pregnancy.Material and MethodsThis was a prospective cohort study between January 2011 and June 2017, based in a University hospital in London, UK. The population consisted of four groups: Group 1 included women without history of CH, presenting in the first trimester with BP>140/90 mmHg (n=100). Groups 2 ‐4 had pre‐pregnancy CH; Group 2 had BP
Source: Acta Obstetricia et Gynecologica Scandinavica - February 20, 2021 Category: OBGYN Authors: Dan Dumitrascu ‐Biris, Diane Nzelu, Theodore Dassios, Kypros Nicolaides, Nikos A Kametas Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Acceptability of immediate postpartum and post ‐abortion long‐acting reversible contraception provision to adolescents: A systematic review
ConclusionsImmediate insertion of LARC postpartum appears acceptable to adolescents who do not experience side ‐effects and those with the opportunity to make autonomous contraception decisions. This important topic has been addressed in few studies involving an entirely adolescent population. Very limited evidence is available on IPA LARC. Further research on adolescents’ lived experiences of IPP/IPA LA RC access and use is necessary to inform the provision of person‐centred care when assisting adolescents’ contraceptive choice following pregnancy. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 20, 2021 Category: OBGYN Authors: Pip Buckingham, Jessica E. Moulton, Asvini K. Subasinghe, Natalie Amos, Danielle Mazza Tags: SYSTEMATIC REVIEW Source Type: research

TSH and FT4 fail to predict the severity and clinical course of hyperemesis gravidarum: a prospective cohort study
ConclusionsOur findings show an inconsistent role for TSH, TSH MoM or FT4 at time of admission and provide little guidance on the severity and clinical course of HG. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 19, 2021 Category: OBGYN Authors: Kelly Nijsten, Marjette H Koot, Joris AM van der Post, Joke MJ Bais, Carrie Ris ‐Stalpers, Christiana Naaktgeboren, Henk A Bremer, David P van der Ham, Wieteke M Heidema, Anjoke Huisjes, Gunilla Kleiverda, Simone M Kuppens, Judith OEH van La Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Effect of SARS ‐CoV‐2 infection during the second half of pregnancy on fetal growth and hemodynamics: a prospective study
ConclusionsPregnancies complicated by SARS ‐CoV‐2 infection are not at higher risk of developing fetal growth restriction due to impaired placental function. The findings from this study do not support a policy of increased fetal surveillance in these women. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 19, 2021 Category: OBGYN Authors: Giuseppe Rizzo, Ilenia Mappa, Pavjola Maqina, Victoria Bitsadze, Jamilya Khizroeva, Alexander Makatsarya, Francesco D ’Antonio Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Quality of life after maternal near miss: A systematic review
ConclusionsEvidence shows that maternal near miss is negatively associated with various aspects of quality of life. This highlights the importance of addressing the adverse effects associated with maternal near miss and follow up maternal near miss after discharge. Quality of life is a multidimensional concept that is assessed in various ways, and the literature on the field is heterogenous. More high ‐quality studies are needed. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 18, 2021 Category: OBGYN Authors: Ida Erika Wieborg Von Rosen, Rayan Mohamud Shiekh, Bariki Mchome, Chunsen Wu, Khalid S. Khan, Vibeke Rasch, Ditte S øndergaard Linde Tags: SYSTEMATIC REVIEW Source Type: research

Breech and induction. Time for evidence ‐based informed consent
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 18, 2021 Category: OBGYN Authors: Jeppe B. Schroll, Lone Krebs Tags: LETTER TO THE EDITOR Source Type: research

Training of health care providers and use of long acting reversible contraception in low ‐to‐middle income countries: A systematic review
ConclusionsDespite heterogeneity, current evidence indicates that training of healthcare providers in LARC may increase the uptake amongst women in low ‐ and middle‐income countries. More robust studies are warranted to inform policy. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 17, 2021 Category: OBGYN Authors: Rasmus Stokholm B ækgaard, Eirik Gjærevold Damhaugh, Dorah Mrema, Vibeke Rasch, Khalid Saeed Khan, Ditte S. Linde Tags: SYSTEMATIC REVIEW Source Type: research

The association between human papillomavirus and cervical high ‐grade cytology among HIV‐positive and HIV‐negative Tanzanian women: A cross‐sectional study
ConclusionsIncreasing age, early age at first intercourse, HR ‐HPV, and HIV infections were associated with a substantially increased risk of HGC. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 17, 2021 Category: OBGYN Authors: Patricia Swai, Susanne K. Kjaer, Bariki Mchome, Rachel Manongi, Sia E. Msuya, Chun Sen Wu, Marianne Waldstrom, Thomas Iftner, Julius Mwaiselage, Vibeke Rasch Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The value of HE4, D ‐dimer, and fibrinogen compared to CA125 alone in triaging women presenting with pelvic masses: a retrospective cohort study
AbstractIntroductionCancer antigen 125 (CA125), the biomarker in common clinical use for ovarian cancer, is limited by low sensitivity for early disease and high false positives. The aim of this study was to evaluate several candidate biomarkers, alone or in combination, compared to CA125 in the prediction of malignant/borderline vs benign tumor status in pre ‐ and post‐menopausal women with pelvic masses.Material and methodsThis was a retrospective observational cohort study set in St. James ’s Hospital, a tertiary referral centre for gynecological malignancy in Dublin, Ireland. Women undergoing surgery for pelv...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 16, 2021 Category: OBGYN Authors: Kate McKendry, Stephen Duff, Yanmei Huang, Mostafa Redha, Áine Scanlon, Feras Abu Saadeh, Noreen Gleeson, John O’Leary, Lucy Norris, Sharon O’Toole Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Mental health status of pregnant and breastfeeding women during the COVID ‐19 pandemic—A multinational cross‐sectional study
ConclusionsThis multinational study found high levels of depressive symptoms and generalized anxiety among pregnant and breastfeeding women during the COVID ‐19 outbreak. The study findings underline the importance of monitoring perinatal mental health during pandemics and other societal crises to safeguard maternal and infant mental health. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 13, 2021 Category: OBGYN Authors: Michael Ceulemans, Veerle Foulon, Elin Ngo, Alice Panchaud, Ursula Winterfeld, L éo Pomar, Valentine Lambelet, Brian Cleary, Fergal O'Shaughnessy, Anneke Passier, Jonathan L. Richardson, Titia Hompes, Hedvig Nordeng Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Agreement between careHPV and hybrid capture 2 in detecting high ‐risk HPV in women in Tanzania
ConclusionsA substantial agreement was found betweencareHPV and HC2 in detecting HPV overall as well as detecting HPV among women with cervical high ‐grade lesions. However, given the limited resources available in low and middle‐income countries, the HPV testing assay should be weighed against the cost‐effectiveness of the test. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 13, 2021 Category: OBGYN Authors: Johnson Katanga, Susanne K. Kjaer, Rachel Manongi, Andrea B. Pembe, Thomas Iftner, Marianne Waldstrom, Julius Mwaiselage, Vibeke Rasch Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype —population‐based life‐course data from birth to late fertile age
ConclusionsThis study provides further evidence of the associations between endometriosis and body size and adiposity, specifically in women with peritoneal endometriosis. The associations are evident in adulthood but not in childhood or adolescence. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 13, 2021 Category: OBGYN Authors: Henna ‐Riikka Rossi, Rozenn Nedelec, Marjo‐Riitta Jarvelin, Sylvain Sebert, Outi Uimari, Terhi T. Piltonen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Evaluation of repeat testing of a non ‐sequencing based NIPT test on a Finnish general‐risk population
ConclusionsRepeating test failures with a second plasma sample could significantly reduce the effective failure rate, thereby providing a way to effectively minimize test failures and further improving clinical utility and test performance. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 12, 2021 Category: OBGYN Authors: Filip Karlsson, Tarja Ahola, Jenny Dahlberg, Lawrence Prensky, Helena Moilanen, Heli Spalding Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal and newborn health risks of climate change: A call for awareness and global action
ABSTRACTClimate change represents one of the largest global health threats of the 21st century with immediate and long ‐term consequences for the most vulnerable populations, especially in the poorest countries with the least capacity to adapt to climate change. Pregnant women and newborns are increasingly being recognized as vulnerable populations in the context of climate change. The effects can be direct or ind irect through heat stress, extreme weather events and air pollution, potentially impacting both the immediate and long‐term health of pregnant women and newborns through a broad range of mechanisms. In 2008, ...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 11, 2021 Category: OBGYN Authors: Nathalie Roos, Sari Kovats, Shakoor Hajat, Veronique Filippi, Matthew Chersich, Stanley Luchters, Fiona Scorgie, Britt Nakstad, Olof Stephansson, Chamnha consortium, Matthew Chersich, Jeremy Hess, Kadiatou Kadio, Seni Kouanda, Sari Kovats, Tags: COMMENTARY Source Type: research

Benefits and potential harms of human papillomavirus (HPV) ‐based cervical cancer screening: A real‐world comparison of HPV testing versus cytology
ConclusionsCompared with cytology ‐based screening, HPV‐based screening provided a 90% increased CIN3+ detection at the cost of a three‐fold increase in colposcopy referrals, when considering complete data from the prevalence round. Our findings support implementation of HPV‐based screening in Denmark, but modifications of s creening algorithms may be warranted to decrease unnecessary colposcopy referrals. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 11, 2021 Category: OBGYN Authors: Louise T. Thomsen, Susanne K. Kj ær, Christian Munk, Dorthe Ørnskov, Marianne Waldstrøm Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal and perinatal outcomes related to COVID ‐19 and pregnancy: overview of systematic reviews
ConclusionsOnly one of 52 systematic reviews had a low risk of bias. Results were heterogenous and the overlap of primary studies was frequently very high between pairs of systematic reviews. High quality evidence syntheses of comparative studies are needed to guide future clinical decisions. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 9, 2021 Category: OBGYN Authors: Laura Vergara ‐Merino, Nicolás Meza, Constanza Couve‐Pérez, Cynthia Carrasco, Luis Ortiz‐Muñoz, Eva Madrid, Sandra Bohorquez‐Blanco, Javier Pérez‐Bracchiglione Tags: SYSTEMATIC REVIEW Source Type: research

A population ‐based combination strategy to improve the cervical cancer screening coverage rate in Bamako, Mali
ConclusionsIn an impoverished context, a multi ‐component strategy significantly increases cervical cancer screening participation. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 9, 2021 Category: OBGYN Authors: Ibrahima T éguété, Fatoumata Korika Tounkara, Broulaye Diawara, Sidy Traoré, Diakaridia Koné, Aliou Bagayogo, Abdoulaye Sissoko, Cheick B Traoré Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Obstetric outcomes for twins from different conception methods – a multicentre cross‐sectional study from China
ABSTRACTIntroductionThe effects of assisted reproductive technology on the outcomes of twin pregnancies are controversial. Therefore, the purpose of this study was to compare the maternal and perinatal outcomes of twin pregnancies conceived spontaneously and those conceived by assisted reproductive technology.Material and methodsThis was a cross ‐sectional study performed at Peking Union Medical College Hospital (PUMCH). Data on twin pregnancies (conceived spontaneously and byin vitro fertilization [IVF]/intracytoplasmic sperm injection [ICSI]) were obtained from the National Birth Registry of China for the period betwee...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Fang Jiang, Jinsong Gao, Jing He, Yabing Tang, Yinli Cao, Xietong Wang, Xiaowei Liu, Tianyun Wang, Xinghui Liu, Jingxia Sun, Mei Zhong, Xiaohong Liu, Shixiu Liao, Caixia Liu, Jinying Yang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Placental volume in gestational week 27 measured by three dimensional ultrasound and magnetic resonance imaging
ConclusionsWe found poor to moderate correlation between 3D ultrasound and MRI placental volume measurements. Generally, 3D ultrasound measured smaller placental volumes than MRI, suggesting that 3D ultrasound failed to visualize the entire placenta. Our findings may hopefully contribute to the improvement of ultrasound methods for placental measurements. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Karianne Sagberg, Anne Eskild, Silje Sommerfelt, Kjell Inge Gjesdal, Lucy E. Higgins, Arne Borthne, Vigdis Hillestad Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Acceptability and feasibility of self ‐sampling and follow‐up attendance after text message delivery of HPV results: A cross‐sectional study nested in a cohort in rural Tanzania
ConclusionsHPV self ‐sampling and text‐messages feedback delivery are generally well‐perceived and accepted among rural Tanzanian women, and the majority of HPV‐positive women attended a follow‐up appointment after receiving their HPV results and follow‐up appointment via text messages. This screening metho d may have potential to be transferrable to other low‐income countries with a high incidence of cervical cancer and thus improve cervical cancer screening attendances. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Alex Mremi, Ditte S øndergaard Linde, Bariki Mchome, Joseph Mlay, Doris Schledermann, Jan Blaakær, Vibeke Rasch Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Attitudes towards comparison of male and female genital cutting in a Swedish Somali population
ConclusionsThe increased global attention and emphasis on the comparability of genital cutting of boys and girls was not reflected in this study among Swedish Somalis. Rather, attitudes reflected the common description of the two practices in global public health campaigns, portraying FGC as a harmful practice violating children ’s rights, while describing MGC as a public health measure. Further, social interactions and disintegration of FGC from religion could explain why FGC and MGC were not considered comparable. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Adam Hanberger, Birgitta Ess én, Anna Wahlberg Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Obstetrics, genetics, and litigation
ConclusionsMany lessons and recommendations emerge in this report. These include the realization that the vast majority of errors in this series involved at least two caregivers, serial ultrasound studies are important, decreased fetal movements may signal a genetic disorder, congenital abnormality, or syndrome, family history and ethnicity are vital, cognitive biases profoundly affect decision ‐making. Finally, the simplest of errors have the potential for causing life‐long grief. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Aubrey Milunsky Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Adding a low ‐quality blastocyst to a high‐quality blastocyst for a double embryo transfer does not decrease pregnancy and live birth rate
ConclusionsWhen there is one HQB available, transferring an additional low ‐quality blastocyst would only slightly increase the LBR, but significantly increase the twin rate, therefore SET should be recommended. When two or more HQBs are available, SET‐H would have a reasonably good chance of success without the very high twin rate associated with DET‐HH. DET‐LL wh en compared with SET‐L, would increase the LBR, but increase the risk of multiple gestation. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Efstathios Theodorou, Benjamin P. Jones, Suzanne Cawood, Carleen Heath, Paul Serhal, Jara Ben ‐Nagi Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Intrapartum ultrasound before instrumental vaginal delivery: We still have room left to grow
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Joana Barros, Diogo Ayres ‐de‐Campos, Luís Mendes da Graça Tags: LETTER TO THE EDITOR Source Type: research

The challenge of defining predictive parameters for fertility preservation counseling in young females with Turner syndrome
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 8, 2021 Category: OBGYN Authors: Sapthami Nadesapillai, Janielle Velden, Didi Braat, Ron Peek, Kathrin Fleischer Tags: LETTER TO THE EDITOR Source Type: research

Body size during adulthood, but not in childhood associates with endometriosis, specifically in the peritoneal subtype – population‐based life‐course data from birth to late fertile age
ConclusionsThis study provides further evidence of the associations between endometriosis and body size and adiposity, specifically in women with peritoneal endometriosis. The associations are evident in adulthood but not in childhood or adolescence. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 7, 2021 Category: OBGYN Authors: Henna ‐Riikka Rossi, Rozenn Nedelec, Marjo‐Riitta Jarvelin, Sylvain Sebert, Outi Uimari, Terhi T. Piltonen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Thirty years of a story of innovation and change in women ’s healthcare
ABSTRACTSince its introduction in 1990, the levonorgestrel ‐releasing intrauterine system (LNG‐IUS) has played a key role in shaping the healthcare landscape of women. Here we explore the development of the first LNG‐IUS (Mirena®) and the early clinical trials that demonstrated its potential. We highlight the contraceptive and therapeutic benefits of Mirena, and discuss how clinical practice has been changed since the introduction of LNG ‐IUS and other long‐acting reversible contraceptive methods. The history of Mirena is rich in innovation and has also paved the way to the development of smaller intrauterine...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 6, 2021 Category: OBGYN Authors: Kristina Gemzell ‐Danielsson, Ali Kubba, Cecilia Caetano, Thomas Faustmann, Eeva Lukkari‐Lax, Oskari Heikinheimo Tags: COMMENTARY Source Type: research

Do stress and anxiety in early pregnancy affect the progress of labor: Evidence from the Wirral Child Health and Development Study
AbstractIntroductionDespite widespread belief that anxiety causes longer labor, evidence of association is inconsistent. Data gathered as part of a prospective epidemiological longitudinal study were used to investigate associations between antenatal anxiety and pregnancy ‐specific stress, and labor progression was assessed by duration and use of augmentation.Material and methodsPregnant primiparous women completed measures for anxiety and pregnancy ‐specific stress at 20 weeks’ gestation (n = 1145). Birth outcome data were extracted from medical records. Regression analyses and a path analysis ass...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 5, 2021 Category: OBGYN Authors: Pauline Slade, Kayleigh Sheen, Andrew Weeks, Susan Wray, Leonardo De Pascalis, Karen Lunt, Carol Bedwell, Belinda Thompson, Johnathan Hill, Helen Sharp Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Risk factors for postpartum depressive symptoms among fathers: a systematic review and meta ‐analysis
ConclusionsA prior history of paternal mental illness, maternal depression, and diverse psychosocial factors were associated with depressive symptoms among fathers postnatally. These findings can guide the development of family ‐level interventions for early identification and treatment and social media campaigns to promote help‐seeking behaviors and engagement in preventive strategies. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 4, 2021 Category: OBGYN Authors: Najmus Sehr Ansari, Jyotsna Shah, Cindy ‐Lee Dennis, Prakesh S. Shah Tags: SYSTEMATIC REVIEW Source Type: research

Frozen section diagnosis of borderline ovarian tumors with suspicious features of invasive cancer is a devil ’s dilemma for the surgeon: a systematic review and meta‐analysis
ABSTRACTIntroductionFrozen section diagnoses of borderline ovarian tumors are not always straightforward and a borderline frozen section diagnosis with suspicious features of invasive carcinoma (reported as “at least borderline” or synonymous descriptions) presents us with the dilemma of whether or not to perform a full surgical staging procedure. By performing a systematic review and meta‐analysis the prevalence of straightforward borderline and “at least borderline” frozen section diagnoses , as well as proportion of patients with a final diagnosis of invasive carcinoma in these cases, were asse...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 4, 2021 Category: OBGYN Authors: Koen De Decker, Karina H. Jaroch, Mireille A. Edens, Joost Bart, Loes F.S. Kooreman, Roy F.P.M. Kruitwagen, Hans W. Nijman, Arnold ‐Jan Kruse Tags: SYSTEMATIC REVIEW Source Type: research

Long ‐term effectiveness of an online decision aid for female cancer patients regarding fertility preservation:Knowledge, attitude, and decisional regret
ConclusionsThis decision aid was suitable as an additional source of knowledge and may positively impact decisional regret in the long term. Results suggest that the provision of an online decision aid as a complement to fertility counseling may facilitate decision ‐making. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 4, 2021 Category: OBGYN Authors: Verena Ehrbar, Ariane Germeyer, Frank Nawroth, Astrid Dangel, Sebastian Findeklee, Corinne Urech, Christoph Rochlitz, Ruth Stiller, Sibil Tschudin Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Psychological impact and social support in pregnant women during lockdown due to SARS ‐CoV2 pandemic: A cohort study
ConclusionsA lockdown scenario during the first wave of the SARS ‐CoV 2 pandemic increased the symptoms of anxiety and depression among pregnant women, particularly affecting those with less social support. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 3, 2021 Category: OBGYN Authors: Maia Brik, Miguel Angel Sandonis, Sara Fern ández, Anna Suy, Gemma Parramon‐Puig, Nerea Maiz, Maria Emilia Dip, Josep Antoni Ramos‐Quiroga, Elena Carreras Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Induction of labor in breech presentations ‐ a retrospective cohort study
In this study, we aimed to compare the outcomes of spontaneous and induced breech deliveries and to describe variations in induction rates.Material and methodsThis was a retrospective cohort study comprising 1054 singleton live fetuses in breech presentation at Trondheim University Hospital from 2012 to 2019. The main outcome was intrapartum cesarean section, and secondary outcomes were postpartum hemorrhage, anal sphincter ruptures, Apgar scores, pH in the umbilical artery, and metabolic acidosis. All data were obtained from the hospital birth journal.ResultsInduction of labor was performed in 127/606 (21.0%) women with p...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 2, 2021 Category: OBGYN Authors: Johanne Augusta Horn Welle ‐Strand, Christian Tappert, Torbjørn Moe Eggebø Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The impact of cardiovascular diseases on maternal deaths in the Nordic countries
ConclusionsBetween 2005 and 2017, cardiovascular diseases were the most common causes of maternal deaths in the Nordic countries. There appears to be a clear potential for a further reduction in these maternal deaths. Increased awareness of cardiac symptoms in pregnant women seems warranted. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 1, 2021 Category: OBGYN Authors: Lill T. Nyfl øt, Marianne Johansen, Ajlana Mulic‐Lutvica, Mika Gissler, Birgit Bødker, Katarina Bremme, Liv Ellingsen, Siri Vangen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Association of peripartum management and high maternal blood loss at cesarean delivery for placenta accreta spectrum (PAS): a multinational database study
ConclusionsIn pregnant women with PAS, the likelihood of blood loss> 3500ml was reduced in planned vs. unplanned cesarean delivery, and when the surgery was performed by a specialist experienced in the management of PAS. This reinforces the necessity of delivery by an expert team. Conservative management was also associated with lower blood loss, but only if successful. Therefore, careful patient selection is of high importance. Our study showed no consistent benefit of other adjunct measures, such as arterial occlusion techniques, uterotonics, and tranexamic acid. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 1, 2021 Category: OBGYN Authors: Alexander Schwickert, Heleen J. van Beekhuizen, Charline Bertholdt, Karin A. Fox, Gilles Kayem, Olivier Morel, Marcus J. Rijken, Vedran Stefanovic, Gita Strindfors, Alexander Weichert, Katharina Weizsaecker, Thorsten Braun, The International S Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The association between human papillomavirus and cervical high ‐grade cytology among HIV positive and HIV negative Tanzanian women: a cross sectional study
ConclusionsIncreasing age, early age at first intercourse, HR HPV and HIV infections were associated with a substantially increased risk of HGC. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - January 29, 2021 Category: OBGYN Authors: Patricia Swai, Susanne K. Kjaer, Bariki Mchome, Rachel Manongi, Sia E. Msuya, Chun Sen Wu, Marianne Waldstrom, Thomas Iftner, Julius Mwaiselage, Vibeke Rasch Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Agreement between careHPV and Hybrid capture 2 (HC2) in detecting high ‐risk HPV in women in Tanzania
Conclusionsa substantial agreement was found between careHPV and HC2 in detecting HPV overall as well as detecting HPV among women with cervical high ‐grade lesions. However, given the limited resources available in low and middle‐income countries, the HPV testing assay should be weighed against the cost effectiveness of the test. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - January 26, 2021 Category: OBGYN Authors: Johnson Katanga, Susanne K. Kjaer, Rachel Manongi, Andrea B. Pembe, Thomas Iftner, Marianne Waldstrom, Julius Mwaiselage, Vibeke Rasch Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Cognitive impairment in preeclampsia complicated by eclampsia and pulmonary edema after delivery
ConclusionsWomen with preeclampsia complicated by pulmonary edema and in particular eclampsia had impaired cognitive function after onset of disease compared to women with normotensive pregnancies. The impairment did not seem to be present before onset of disease. Women with preeclampsia without severe features did not have impaired cognitive function. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - January 25, 2021 Category: OBGYN Authors: Lina Bergman, Lilja Thorgeirsdottir, Helen Elden, Susanne Hesselman, Sonja Schell, Evelina Ahlm, Annet Aukes, Catherine Cluver Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Fear of childbirth after medical versus surgical abortion. Population ‐based register study from Finland
AbstractIntroductionTo evaluate the effect of method of induced abortion and other abortion ‐associated variables on the incidence of fear of childbirth in subsequent pregnancy.Material and methodsThis population ‐based register study cohort includes all nulliparous women with their first pregnancy ending in an induced abortion in 2000‐2015 and subsequent pregnancy with live singleton delivery between 2000 and 2017 (n = 21 479). Data were derived from three national registers maintained by the Finnish Institute for Health and Welfare. We divided the study population in three cohorts: (a) medical and (b...
Source: Acta Obstetricia et Gynecologica Scandinavica - January 24, 2021 Category: OBGYN Authors: Venla Kemppainen, Maarit Niinim äki, Aini Bloigu, Terhi Saisto, Hanna Rouhe, Mika Gissler, Oskari Heikinheimo, Maarit Mentula Tags: ORIGINAL ARTICLE Source Type: research

Short ‐term outcomes of endometriosis surgery in Ontario: A population‐based cohort study
ConclusionsApproximately one ‐third of patients undergoing surgical management for endometriosis in Ontario between 2002 and 2018 had a hysterectomy. Overall, complications following surgery were low, and dependent on extent of surgery. These results should help to inform preoperative counseling for patients and health policy development for providers. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - January 24, 2021 Category: OBGYN Authors: Olga Bougie, Chad McClintock, Jessica Pudwell, Susan B. Brogly, Maria P. Velez Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Preoperative vaginal cleansing with chlorhexidine solution in preventing post ‐cesarean section infections in a low resource setting: A randomized controlled trial
This study is aimed at evaluating the efficacy of preoperative vaginal cleansing using 1.0% chlorhexidine in the reduction of post ‐cesarean section infectious morbidities.Material and methodsThis prospective randomized control trial was conducted among 322 pregnant women who underwent an emergency cesarean section at Alex Ekwueme Federal University Teaching Hospital, Abakaliki (AE ‐FUTHA). The women were randomized into two groups. The interventional group received vaginal cleansing with three standard gauzes soaked in 30 mL 1.0% chlorhexidine gluconate solution preoperatively in addition to surgical skin cleanin...
Source: Acta Obstetricia et Gynecologica Scandinavica - January 23, 2021 Category: OBGYN Authors: Christian O. Ogah, Chidebe C. Anikwe, Leonard O. Ajah, Arinze C. Ikeotuonye, Osaheni L. Lawani, Bartholomew C. Okorochukwu, Cyril C. Ikeoha, Francis C. Okoroafor Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

A multicenter observational survey of management strategies in 442 pregnancies with suspected placenta accreta spectrum
ABSTRACTIntroductionManagement of women with placenta accreta spectrum (PAS) are: termination of pregnancy before the viable gestational age, leaving the placenta in situ for subsequent reabsorption of the placenta or delayed hysterectomy, manual removal of placenta after vaginal delivery or during cesarean section, focal resection of the affected uterine wall, and peripartum hysterectomy. The aim of this observational study was to describe actual clinical management and outcomes in PAS in a large international cohort.Material and methodsData from women in 15 referral centers of the International Society of PAS (IS ‐PAS)...
Source: Acta Obstetricia et Gynecologica Scandinavica - January 23, 2021 Category: OBGYN Authors: Heleen J. van Beekhuizen, Vedran Stefanovic, Alexander Schwickert, Wolfgang Henrich, Karin A. Fox, Mina MHallem Gziri, Lo ïc Sentilhes, Lene Gronbeck, Frederic Chantraine, Oliver Morel, Charline Bertholdt, Thorsten Braun, Marcus J. Rijken, J Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The #Enzian classification: A comprehensive non ‐invasive and surgical description system for endometriosis
AbstractAdvances in preoperative diagnostic as well as surgical techniques for the treatment of endometriosis, especially deep endometriosis call for a classification system that includes all aspects of the disease such as peritoneal, ovarian endometriosis and deep endometriosis and secondary adhesions. The widely accepted r ‐ASRM classification has certain limitations due to its incomplete description of deep endometriosis. In contrast, the Enzian classification, which has been implemented in the last decade, has proved to be the most suitable tool for staging deep endometriosis but does not include peritoneal or ova ri...
Source: Acta Obstetricia et Gynecologica Scandinavica - January 23, 2021 Category: OBGYN Authors: Joerg Keckstein, Ertan Saridogan, Uwe A. Ulrich, Martin Sillem, Peter Oppelt, Karl W. Schweppe, Harald Krentel, Elisabeth Janschek, Caterina Exacoustos, Mario Malzoni, Michael Mueller, Horace Roman, George Condous, Axel Forman, Frank W. Jans Tags: COMMENTARY Source Type: research