Use of medication in pregnancy on the rise: Study on 1.4  million Danish pregnancies from 1998 to 2018
ConclusionsMedication use in general, and polypharmacy in particular, increased from 1998 to 2008, possibly as the result of an increased prevalence of pregnant women with chronic conditions requiring pharmacological treatment. Notably, a marked maternal age-based discrepancy in usage pattern was observed, highlighting the need for further research in this area. The rise in the prevalence of polypharmacy during pregnancy underscores the need for pharmacovigilance to monitor adverse effects. Future studies should investigate the patterns of polypharmacy and the accompanying maternal and fetal risks. (Source: Acta Obstetrici...
Source: Acta Obstetricia et Gynecologica Scandinavica - March 16, 2024 Category: OBGYN Authors: Mette Østergaard Thunbo, Julie Hauer Vendelbo, Daniel R. Witte, Agnete Larsen, Lars Henning Pedersen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Right ventricular outflow tract obstruction in twin ‐to‐twin transfusion syndrome undergoing laser surgery: A systematic review and meta‐analysis
ConclusionsRVOT occurs in about 6% of the recipient twins with TTTS, especially in stages III and IV and those with reversed ductus venosus a-wave. The findings from this systematic review support the need for a thorough cardiac assessment of pregnancies complicated by TTTS, both before and after laser, to maximize perinatal outcome, and the importance of early diagnosis of TTTS and timely management. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Hiba J. Mustafa, Muhammad Jawwad, Ayesha Iqbal  Mansoor, Giorgio Pagani, Francesco D'Antonio, Asma Khalil Tags: SYSTEMATIC REVIEW Source Type: research

Associations between arterial health and sexual function in women aged 60 –64 years
ConclusionsThis study suggested a plausible association between higher diastolic blood pressure and female sexual function, but considering clinical significance our findings suggest an association between higher ankle –brachial index and good sexual function in women in their 60s. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Viivi Virkkunen, Katja Kero, Mari Koivisto, Teemu Niiranen, Olli Heinonen, Sari Stenholm, P äivi Polo‐Kantola Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Prediction of preterm birth in women with fetal growth restriction – Is the weekly change in sFlt‐1/PlGF ratio or PlGF levels useful?
ConclusionsBoth a high sFlt-1/PlGF ratio and low PlGF levels are predictive of preterm birth in women with fetal growth restriction. Although the rate of increase of the sFlt-1/PlGF ratio predicts preterm birth, it is not superior to either a single elevated sFlt-1/PlGF ratio or low PlGF level. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Jesrine Hong, Kylie Crawford, Erika Cavanagh, Vicki Clifton, Sailesh Kumar Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Correction to " Bhatia K, Columb M, Narayan B, Wilson A; Group of Obstetric Anesthetists of Lancashire; Greater Manchester and Mersey (GOAL ‐GM) Study Collaborators. Critical care, maternal and neonatal outcomes of pregnant women with COVID‐19 admitted to eight intensive care units during the wildtype, alpha and delta waves of the pandemic across the North West of England‐a retrospective review. Acta Obstet Gynecol Scand. 2023 Dec ;102(12):1719‐1729. doi: 10.1111/aogs.14681. Epub 2023 Sep 20. PMID: 37727968; PMCID: PMC10619604."
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Tags: CORRECTION Source Type: research

Progestogens in women with threatened miscarriage or recurrent miscarriage: A meta ‐analysis
ConclusionsIn women at increased risk of pregnancy loss, progestogens probably increase live births without increasing adverse maternal and neonatal events. It remains possible that the benefit is restricted to those with prior miscarriages. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 14, 2024 Category: OBGYN Authors: Yunli Zhao, Rohan D'Souza, Ya Gao, Qiukui Hao, Lucas Kallas ‐Silva, Jeremy P. Steen, Gordon Guyatt Tags: SYSTEMATIC REVIEW Source Type: research

The role of multiple high ‐risk human papillomavirus infection on the persistence recurrence of high‐grade cervical lesions after standard treatment: A systematic review and a meta‐analysis
ConclusionsMultiple HR-HPVs infections at the time of standard treatment of HSIL entail a small but significant increased risk of persistence/recurrence of HSIL and should be taken into account in the follow-up plan. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 13, 2024 Category: OBGYN Authors: Chiara Cassani, Mattia Dominoni, Marianna Francesca Pasquali, Barbara Gardella, Arsenio Spinillo Tags: SYSTEMATIC REVIEW Source Type: research

Association between postpartum depression and postpartum hemorrhage: A systematic review and meta ‐analysis
ConclusionsWomen with PPH must be closely monitored because they have a higher risk of PPD than women without PPH. Early recognition and management of these patients will improve treatment outcomes, maternal health, and newborn development. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 13, 2024 Category: OBGYN Authors: Bo Sheng, Guoguo Jiang, Juan Ni Tags: SYSTEMATIC REVIEW Source Type: research

Ethnic background as a risk factor for permanent brachial plexus birth injury: A population ‐based study
ConclusionsShoulder dystocia and assisted delivery are the most important risk factors for a permanent brachial plexus birth injury. Black race was associated with a higher rate and a more severe permanent brachial plexus birth injury. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 12, 2024 Category: OBGYN Authors: Petra Grahn, Mika Gissler, Yrj änä Nietosvaara, Marja Kaijomaa Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The effects of intravenous hydration regimens in nulliparous women undergoing induction of labor: A systematic review and meta ‐analysis
ConclusionsOur review found no significant improvements for nulliparous women who received higher intravenous fluid volumes when undergoing induction of labor and were not routinely fasted. However, data are limited, and further research is needed. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 12, 2024 Category: OBGYN Authors: Lauren Kearney, Susannah Brady, Nicole Marsh, Miranda Davies ‐Tuck, Rachael Nugent, Victoria Eley Tags: SYSTEMATIC REVIEW Source Type: research

Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three ‐Generation Cohort Study
ConclusionsExposure to HDP during fetal life is associated with offspring developmental delay. This association is partly mediated by neonatal outcomes. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 8, 2024 Category: OBGYN Authors: Geng Chen, Mami Ishikuro, Hisashi Ohseto, Keiko Murakami, Aoi Noda, Genki Shinoda, Masatsugu Orui, Taku Obara, Shinichi Kuriyama Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Diet quality and blood pressure among pregnant women with overweight or obesity: A secondary analysis of two randomized controlled trials
ConclusionsWhile diet remains an important factor in maternal health and wellbeing, we did not find a relationship between diet quality as measured by AHEI-P and blood pressure among pregnant women with BMI ≥25 kg/m2. High BMI remains a risk factor for hypertensive disorders of pregnancy. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 7, 2024 Category: OBGYN Authors: Sorcha Lynch, Sarah Louise Killeen, Eileen O'Brien, Kate Mullane, Emma Hokey, Grace Mealy, Fionnuala M. McAuliffe Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal gestational hypertension, smoking and pre ‐eclampsia are associated with metabolic dysfunction‐associated fatty liver disease in overweight offspring
ConclusionsMaternal smoking, gestational hypertension and pre-eclampsia were associated with MAFLD among overweight or obese children. Further prospective studies are needed to verify causal relationships. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 4, 2024 Category: OBGYN Authors: Hanna de Ruyter, Linnea Aitokari, Siiri Lahti, Hanna Riekki, Heini Huhtala, Timo Lakka, Hannele Laivuori, Kalle Kurppa Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Long ‐term outcomes of children after prenatal exposure to maternal cancer and its treatment
We describe the short and long-term child outcomes after prenatal exposure to maternal cancer(treatment) and the gaps of knowledge wich need to be elucidated in future research. AbstractThe incidence of antenatal cancer is increasing, prompting a medical-ethical evaluation. The International Network on Cancer, Infertility, and Pregnancy (INCIP) was established to study cancer treatment safety during pregnancy and its impact on maternal and child health. Pivotal research has led to a paradigm shift in clinical management, demonstrating the feasibility and safety of most antenatal oncological treatments. Short-term outcomes ...
Source: Acta Obstetricia et Gynecologica Scandinavica - February 29, 2024 Category: OBGYN Authors: Evangeline A. Huis  in ’t Veld, Indra A. Van Assche, Frederic Amant Tags: COMMENTARY Source Type: research

Perinatal outcomes following fetoscopic laser surgery for early twin ‐to‐twin transfusion syndrome: Systematic review and meta‐analysis
ConclusionsIn early TTTS treated with FLS, outcomes were comparable between those treated at<18  weeks compared with ≥18 weeks except for GA at delivery, which was 3 weeks earlier. In the subset treated at<16  weeks vs 16–18 weeks, the procedure was feasible without an increased risk of very early preterm birth or perinatal mortality. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 29, 2024 Category: OBGYN Authors: Hiba J. Mustafa, Faezeh Aghajani, Elise Patrick, Maryam M. Baerz, Pedro Arias ‐Sánchez, Asma Khalil Tags: SYSTEMATIC REVIEW Source Type: research