Editor ’s Note: Badawy AM, Elnashar AM, and Mosbah AA. Aromatase inhibitors or gonadotropin‐releasing hormone agonists for the management of uterine adenomyosis: a randomized controlled trial. Acta Obstetricia et Gynecologica Scandinavica, 2012;91:489–495
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 23, 2021 Category: OBGYN Tags: EDITOR ’S NOTE Source Type: research

Editor ’s Note: Badawy A, State O and Abdelgawad S. N‐Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: a cross‐over trial. Acta Obstetricia et Gynecologica Scandinavica, 2007;86:218–222
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 23, 2021 Category: OBGYN Tags: EDITOR ’S NOTE Source Type: research

Editor ’s Note: Badawy A, Shokeir T, Allam AF and Abdelhady H. Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility. Acta Obstetricia et Gynecologica Scandinavica, 2009; 88:187–191
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 23, 2021 Category: OBGYN Tags: EDITOR'S NOTE Source Type: research

Editor ’s Note: Abu Hashim H, Ombar O and Abd Elaal I. Intrauterine insemination versus timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial. Acta Obstetricia et Gynecologica Scandinavica, 2011;90:344–350
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 23, 2021 Category: OBGYN Tags: Editor's Note Source Type: research

Editor ’s Note: Abu Hashim H, EL Rakhawy M and Abd Elaal I. Randomized comparison of superovulation with letrozole versus clomiphene citrate in an IUI program for women with recently surgically treated minimal to mild endometriosis. Acta Obstetricia et Gynecologica Scandinavica, 2012;91:338–345
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 23, 2021 Category: OBGYN Tags: EDITOR ’S NOTE Source Type: research

Long ‐term growth in offspring of infertile parents: a 20‐year follow‐up study
ConclusionsThe main finding was equal long-term growth for children born at term by parents who received fertility treatment or parents waiting more than 12 months to conceive compared to spontaneously conceived children. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 22, 2021 Category: OBGYN Authors: Ninna Hinchely Ebdrup, Lena Hohw ü, Bjørn Bay, Carsten Obel, Ulla Breth Knudsen, Ulrik Schiøler Kesmodel Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Offspring birthweight and placental weight – does the type of maternal diabetes matter? A population‐based study of 319,076 pregnancies
ConclusionsThe increase in birthweight and in placental weight associated with maternal diabetes was most pronounced for type 1 diabetes, followed by type 2 diabetes, and gestational diabetes. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 22, 2021 Category: OBGYN Authors: Ellen Marie Str øm‐Roum, Anne Marie Jukic, Anne Eskild Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Time points and risk factors for RhD immunisations after the implementation of targeted routine antenatal anti ‐D prophylaxis: a retrospective nation‐wide cohort study
ConclusionsThe incidence of new anti-D immunisations decreased expectedly after the implementation of routine antenatal anti-D prophylaxis. True failures are rare and they mainly occur when the prophylaxis is not given appropriately, suggesting a need for constant education of healthcare professionals on the subject. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 22, 2021 Category: OBGYN Authors: Riina Jernman, Camilla Isaksson, Katri Haimila, Malla Kuosmanen, Kaarin M äkikallio‐Anttila, Suvi Toivonen, Maija‐Riitta Ordén, Kati Sulin, Kati Tihtonen, Marja Vääräsmäki, Susanna Sainio Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Soluble fms ‐like tyrosine kinase 1 (sFlt‐1): A novel biochemical marker for acute fatty liver of pregnancy
ABSTRACTIntroductionAcute fatty liver of pregnancy (AFLP) substantially contributes to maternal and neonatal morbidity and mortality. Other liver-associated pregnancy complications such as preeclampsia-associated HELLP (hemolysis, elevated liver enzyme, low platelet) syndrome may be difficult to differentiate from AFLP since these diseases overlap with regard to multiple clinical and laboratory features. The aim of this study was to investigate angiogenic profiles by measuring soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) in pregnancies compromised by AFLP and to compare them to those compl...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 22, 2021 Category: OBGYN Authors: Fabienne Trottmann, Luigi Raio, Sofia Amylidi ‐Mohr, Beatrice Mosimann, Jarquin Campos Araceli, Franz H. Messerli, Lorenz Risch, Marc U. Baumann Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Cervical cancer prevention among older women – challenges in screening, diagnostic workup and treatment
AbstractCervical cancer incidence and mortality have declined dramatically after screening for cervical cancer was implemented. Yet, studies have reported high cervical cancer incidence and mortality rates at older age despite low HPV prevalence and incidence of precursor lesions. The underlying reason for these findings remains unclear. However, it is well known that the impact of screening depends not only on the uptake and effectiveness of screening but also on the uptake and effectiveness of diagnostic workup (ie colposcopy), treatment and follow-up. In older women, sensitivity of screening and performance of colposcop...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 21, 2021 Category: OBGYN Authors: Line W. Gustafson, Lone Kjeld Petersen, Pinar Bor, Berit Andersen, Anne Hammer Tags: COMMENTARY Source Type: research

Progression from isolated gestational proteinuria to preeclampsia with severe features
ConclusionsA higher isolated gestational proteinuria level was associated with an increased risk to develop preeclampsia with severe features among pregnant women past 24  weeks of gestation. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 19, 2021 Category: OBGYN Authors: Yossi Tzur, Eli Rimon, Gil Geva, Jacky Herzlich, Michael J. Kupferminc Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Differences between lactate meters and the importance of considering lactate concentration as a continuum
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 17, 2021 Category: OBGYN Authors: Malin Holzmann, Lennart Nordstr öm, Philip Steer Tags: LETTER TO THE EDITOR Source Type: research

Position therapy in pregnancy: Can trending maternal cardiac output put it on a more objective foundation?
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 14, 2021 Category: OBGYN Authors: Thomas L. Archer Tags: LETTER TO THE EDITOR Source Type: research

Unmet need for evidence of volume ‐outcome relation and maternal outcomes of placenta accreta spectrum
AbstractWe read the study by Nieto-Calvacheet al. with great interest, that examined the causes of death related to placenta accreta spectrum (PAS) and analyzed the associated diagnostic and treatment problems in low and middle income countries. The authors concluded that lack of experience and inadequate surgical technique are the most frequent problems associated with maternal deaths in PAS. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 13, 2021 Category: OBGYN Authors: Hitomi Sakaguchi, Shinya Matsuzaki, Shoji Kamiura Tags: LETTER TO THE EDITOR Source Type: research

Severe recalled labor pain and elective cesarean section in a subsequent delivery: a cohort study of Norwegian parous women
ConclusionsWomen with severe recalled labor pain were about twice as likely to prefer an elective CS compared to women without severe recalled pain. For actual delivery, the significant association with severe recalled pain diminished after adjustment for covariates. However, sample size was small and irrespective of severe recalled labor pain, preference of elective CS was statistically significantly associated with actual delivery by elective CS. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 12, 2021 Category: OBGYN Authors: Carolin Junge, Tilmann von Soest, Andreas Seidler, Malin Eberhard ‐Gran, Susan Garthus‐Niegel Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Time matters – a Swedish cohort study of labor duration and risk of uterine rupture
ConclusionsLabor duration is an independent factor for uterine rupture among women attempting vaginal delivery after cesarean section . Medical induction and augmentation of labor increase the risk, regardless of maternal and birth characteristics. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 11, 2021 Category: OBGYN Authors: Susanne Hesselman, Erik Lampa, Anna Wikman, Anna Eliason T örn, Ulf Högberg, Anna‐Karin Wikström, Maria Jonsson Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Comparison of perioperative outcomes between standard laparoscopic and robot ‐assisted approach in patients with rectosigmoid endometriosis
ConclusionsIf performed by expert teams, RALS provides similar perioperative outcomes compared with S-LPS in rectosigmoid endometriosis surgical treatment, except for longer operative room time. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 11, 2021 Category: OBGYN Authors: Diego Raimondo, Carlo Alboni, Benedetta Orsini, Anna Chiara Aru, Antonino Farulla, Manuela Maletta, Alessandro Arena, Simona Del Forno, Veronica Sampogna, Manuela Mastronardi, Marco Petrillo, Renato Seracchioli Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Maternal death in placenta accreta spectrum: Three possible factors preventing patients ’ transfer
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 10, 2021 Category: OBGYN Authors: Shigeki Matsubara, Daisuke Matsubara, Teppei Matsubara Tags: LETTER TO THE EDITOR Source Type: research

Preoperative and intraoperative assessment of myometrial invasion in endometrial cancer —A Swedish Gynecologic Cancer Group (SweGCG) study
ConclusionsIn Sweden, the assessment of deep myometrial invasion is most often performed with transvaginal sonography, but the sensitivity is lower than for the other diagnostic methods. In clinical practice, the accuracy is moderate for transvaginal sonography and MRI. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 10, 2021 Category: OBGYN Authors: Bj örg Jónsdóttir, Janusz Marcickiewicz, Christer Borgfeldt, Maria Bjurberg, Pernilla Dahm‐Kähler, Angelique Flöter‐Rådestad, Kristina Hellman, Erik Holmberg, Preben Kjølhede, Per Rosenberg, Bengt Tholander, Elisabeth Åvall‐Lundqv Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

COVID ‐19 pandemic and population‐level pregnancy and neonatal outcomes: a living systematic review and meta‐analysis
The objective of our study was to conduct a living systematic review and meta-analyses of studies reporting pregnancy and neonatal outcomes by comparing the pandemic and pre-pandemic periods.Material and methodsWe searched PubMed and Embase databases, reference lists of articles published up until May 14, 2021 and included English language studies that compared outcomes between the COVID-19 pandemic time period vs. pre-pandemic time periods. Risk of bias was assessed using the Newcastle-Ottawa scale. We conducted random-effects meta-analysis using the inverse variance method.ResultsThirty-seven studies with low-to-moderate...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 7, 2021 Category: OBGYN Authors: Jie Yang, Rohan D ’souza, Ashraf Kharrat, Deshayne B. Fell, John W. Snelgrove, Kellie E. Murphy, Prakesh S. Shah Tags: SYSTEMATIC REVIEW Source Type: research

Need updating fetal blood sampling guidelines since lactate levels indicating acidemia are specific to the measuring instrument
(Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 6, 2021 Category: OBGYN Authors: Junaid Rafi Tags: LETTER TO THE EDITOR Source Type: research

A prospective study comparing rectal water ‐contrast transvaginal ultrasonography with sonovaginography for the diagnosis of deep posterior endometriosis
This study aims to investigate the diagnostic performance of rectal water-contrast transvaginal ultrasonography (RWC-TVS) and sonovaginography (SVG) in women with suspicion of posterior DE.Material and methodsThis prospective comparative study (NCT04296760) enrolled women with clinical suspicion of DE at our institution (Piazza della Vittoria 14 SRL, Genoa, Italy). Exclusion criteria were the previous diagnosis of DE by imaging techniques or laparoscopy. All patients underwent RWC-TVS and SVG, independently performed by two gynecologic sonologists blinded to the other technique's results. Patients underwent laparoscopic su...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 6, 2021 Category: OBGYN Authors: Fabio Barra, Umberto Leone Roberti Maggiore, Giulio Evangelisti, Carolina Scala, Franco Alessandri, Valerio Gaetano Vellone, Cesare Stabilini, Simone Ferrero Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Effect of second ‐trimester sonographic cervical length on the risk of spontaneous preterm delivery in different risk groups: a prospective observational multicenter study
ABSTRACTIntroductionThe aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery between different risk groups of asymptomatic women with a singleton pregnancy.Material and methodsThis is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnostic accuracy study. Asymptomatic women with a singleton pregnancy were consecutively recruited at their second-trimester routine ultrasound examination at seven Swedish ultrasound centers. Cervical length was measured with transvaginal...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 6, 2021 Category: OBGYN Authors: Tove Wikstr öm, Henrik Hagberg, Bo Jacobsson, Pihla Kuusela, Jan Wesström, Peter Lindgren, Helena Fadl, Ulla‐Britt Wennerholm, Lil Valentin Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

A prospective study comparing rectal water ‐contrast transvaginal ultrasonography with sonovaginography for the diagnosis of deep posterior endometriosis
This study aims to investigate the diagnostic performance of rectal water-contrast transvaginal ultrasonography (RWC-TVS) and sonovaginography (SVG) in women with suspicion of posterior DE.Material and methodsThis prospective comparative study (NCT04296760) enrolled women with clinical suspicion of DE at our institution (Piazza della Vittoria 14 SRL, Genoa, Italy). Exclusion criteria were the previous diagnosis of DE by imaging techniques or laparoscopy. All patients underwent RWC-TVS and SVG, independently performed by two gynecologic sonologists blinded to the other technique's results. Patients underwent laparoscopic su...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 6, 2021 Category: OBGYN Authors: Fabio Barra, Umberto Leone Roberti Maggiore, Giulio Evangelisti, Carolina Scala, Franco Alessandri, Valerio Gaetano Vellone, Cesare Stabilini, Simone Ferrero Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Effect of second ‐trimester sonographic cervical length on the risk of spontaneous preterm delivery in different risk groups: a prospective observational multicenter study
ABSTRACTIntroductionThe aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery between different risk groups of asymptomatic women with a singleton pregnancy.Material and methodsThis is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnostic accuracy study. Asymptomatic women with a singleton pregnancy were consecutively recruited at their second-trimester routine ultrasound examination at seven Swedish ultrasound centers. Cervical length was measured with transvaginal...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 6, 2021 Category: OBGYN Authors: Tove Wikstr öm, Henrik Hagberg, Bo Jacobsson, Pihla Kuusela, Jan Wesström, Peter Lindgren, Helena Fadl, Ulla‐Britt Wennerholm, Lil Valentin Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Systematic screening for vasa previa at the 20 ‐week anomaly scan
ConclusionsScreening for vasa previa is feasible and efficient, taking into account the site of placental cord insertion in pregnancies not affected by placenta previa and bilobed and succenturiate placenta. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 3, 2021 Category: OBGYN Authors: Anna Gross, Barbara Markota Ajd, Christian Specht, Matthias Scheier Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Placental characteristics in different types of selective fetal growth restriction in monochorionic diamniotic twins
This study aimed to explore the difference in placental characteristics among three types of selective fetal growth restriction (sFGR) in monochorionic diamniotic twin pregnancies.Material and methodsA total of 123 placentas with sFGR between April 2013 and October 2019 were retrospectively analyzed after dye injection. Placental characteristics were compared among the three types.ResultsThe gestational age at diagnosis and delivery was less in sFGR II and III than in sFGR I [22.9 (21.7 –33.6), 23.3 (20.0–26.1), and 25.7 (19.0–35.0) weeks,P
Source: Acta Obstetricia et Gynecologica Scandinavica - June 2, 2021 Category: OBGYN Authors: Xueju Wang, Luyao Li, Pengbo Yuan, Yangyu Zhao, Yuan Wei Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Time to reconsider: have the 2015 FIGO and 2017 Swedish intrapartum cardiotocogram classifications led us from Charybdis to Scylla?
ABSTRACTIn 2015 FIGO revised the 1987 intrapartum CTG classification (FIGO1987). A less radical FIGO2015 version was introduced in Sweden 2017 (SWE2017). Now,post hoc simulation studies show that FIGO2015 and SWE2017 are less reliable than (a modified) FIGO1987. FIGO2015 shows significantly better inter-observer agreement for normal CTG traces than FIGO1987, but significantly worse for pathological traces. Agreements between templates are moderate-good, but different classifications of mainly variable decelerations and tachycardia cause significant heterogeneities. FIGO2015 shows insufficient sensitivity to identify fetal ...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 1, 2021 Category: OBGYN Authors: Per Olofsson, Frida Ekeng ård, Andreas Herbst Tags: COMMENTARY Source Type: research

Treatment with assisted reproduction technologies in women with acute hepatic porphyria
ConclusionsWomen with acute hepatic porphyria considering fertility treatments should be assessed individually for potential risks, treatment should be planned in close collaboration with a porphyria specialist and biochemical activity should be monitored regularly during ovarian stimulation. As we gather more knowledge, we hope that the porphyrinogenicity of stimulation substances is re-assessed and that more studies will shed light on the reproductive health of women living with acute hepatic porphyria. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - June 1, 2021 Category: OBGYN Authors: Daphne Vassiliou, Angelica Lind én Hirschberg, Eliane Sardh Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Time to reconsider: have the 2015 FIGO and 2017 Swedish intrapartum cardiotocogram classifications led us from Charybdis to Scylla?
ABSTRACTIn 2015 FIGO revised the 1987 intrapartum CTG classification (FIGO1987). A less radical FIGO2015 version was introduced in Sweden 2017 (SWE2017). Now,post hoc simulation studies show that FIGO2015 and SWE2017 are less reliable than (a modified) FIGO1987. FIGO2015 shows significantly better inter-observer agreement for normal CTG traces than FIGO1987, but significantly worse for pathological traces. Agreements between templates are moderate-good, but different classifications of mainly variable decelerations and tachycardia cause significant heterogeneities. FIGO2015 shows insufficient sensitivity to identify fetal ...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 1, 2021 Category: OBGYN Authors: Per Olofsson, Frida Ekeng ård, Andreas Herbst Tags: COMMENTARY Source Type: research

Progression from isolated gestational proteinuria to pre ‐eclampsia with severe features
ConclusionsA higher isolated gestational proteinuria level was associated with an increased risk to develop pre-eclampsia with severe features among pregnant women past 24 weeks of gestation. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 28, 2021 Category: OBGYN Authors: Yossi Tzur, Eli Rimon, Gil Geva, Jacky Herzlich, Michael J. Kupferminc Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Changes in rate of preterm birth and adverse pregnancy outcomes attributed to preeclampsia after introduction of a refined definition of preeclampsia: a population ‐based study
ABSTRACTIntroductionSince 2013 various guidelines for hypertension in pregnancy were refined, no longer requiring proteinuria as a requisite for preeclampsia. We aimed to evaluate the impact of the new definition on preterm birth (PTB) and adverse pregnancy outcomes.MethodsWomen delivering in Ontario between 4/2012-11/2016 were included. Delivery
Source: Acta Obstetricia et Gynecologica Scandinavica - May 27, 2021 Category: OBGYN Authors: Shiri Shinar, Nir Melamed, Kasim E. Abdulaziz, Joel G. Ray, Catherine Riddell, Jon Barrett, Beth Murray ‐Davis, Karizma Mawjee, Sarah D. Mcdonald, Michael Geary, Howard Berger, DOH‐NET (Diabetes, Obesity, Hypertension in Pregnancy Research Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Assessment of surgeon and hospital volume for robot ‐assisted and laparoscopic benign hysterectomy in Sweden
ConclusionsRATLH led to better perioperative outcome and higher patient satisfaction 1  year after surgery. These outcome differences were slightly more pronounced in very low-volume surgeons but persisted across all surgeon volume groups. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 26, 2021 Category: OBGYN Authors: Malin Brunes, Catharina Forsgren, Anna Warnqvist, Marion Ek, Ulrika Johannesson Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Recurrence, postponing pregnancy and termination rates after hyperemesis gravidarum: follow ‐up of the MOTHER study
ConclusionsHigh rates of HG recurrence and a high number of postponed pregnancies due to HG were observed. Women can be informed of a high chance of recurrence to enable informed family planning. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 25, 2021 Category: OBGYN Authors: Kelly Nijsten, Caitlin Dean, Lo ïs M. van der Minnen, Joke MJ Bais, Carrie Ris‐Stalpers, Rik van Eekelen, Henk A Bremer, David P van der Ham, Wieteke M Heidema, Anjoke Huisjes, Gunilla Kleiverda, Simone M Kuppens, Judith OEH van Laar, Josj Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Progress in the management of ovarian granulosa cell tumor: A review
AbstractOvarian granulosa cell tumor (GCT) is a rare, low-grade malignant tumor that accounts for 70% of the sex cord-stromal tumors, it has two histopathological types with different clinical and biological features: adult GCT and juvenile GCT. Most women diagnosed with the adult GCT have a favorable prognosis, with a 5-year survival rate of 97-98%, but adult GCT has a feature of late relapse, the recurrence time could be more than 20 years after diagnosis. Juvenile GCT had a survival rate of 97% in stage I and a 5-year survival rate of 0%-22% in advanced stage with earlier relapse than adult GCT. Consequently, the scenar...
Source: Acta Obstetricia et Gynecologica Scandinavica - May 24, 2021 Category: OBGYN Authors: Junting Li, Ran Chu, Zhongshao Chen, Jinyu Meng, Shu Yao, Kun Song, Beihua Kong Tags: STATE ‐OF‐THE‐ART REVIEW Source Type: research

Perinatal outcomes in women with cystic fibrosis: data from the Italian Cystic Fibrosis Registry
AbstractIntroductionData from the Italian Cystic Fibrosis Registry concerning pregnancies in the period 2010-2015 were used to investigate the association between the pre-conception clinical status and perinatal outcomes of women with CF.Material and methodsThe assessed clinical variables were genotype, age at the time of conception, body mass index (BMI), and the percentage of predicted forced expiratory volume in the first second (ppFEV1); the analysed outcomes were gestational age, birthweight, and the frequency of cesarean deliveries. Generalized Linear Mixed model (GLIMMIX) was used to evaluate the association between...
Source: Acta Obstetricia et Gynecologica Scandinavica - May 24, 2021 Category: OBGYN Authors: Rita F. Padoan, Serena Quattrucci, Annalisa Amato, Marco Salvatore, Donatello Salvatore, Giuseppe Campagna Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Challenges in migrant women ’s maternity care in a high‐income country: A population‐based cohort study of maternal and perinatal outcomes
This study aims to explore maternal and perinatal outcomes of migrant women in Iceland.Material and methodsThis prospective population-based cohort study included women who gave birth to a singleton in Iceland between 1997 and 2018, for a total of 92 403 births. Migrant women were defined as women with citizenship other than Icelandic, including refugees and asylum seekers, and categorised into three groups, based on their country of citizenship Human Development Index score. The effect of country of citizenship was estimated. The main outcome measures were onset of labour, augmentation, epidural, perineum support, episiot...
Source: Acta Obstetricia et Gynecologica Scandinavica - May 22, 2021 Category: OBGYN Authors: Embla Ýr Guðmundsdóttir, Helga Gottfreðsdóttir, Berglind Hálfdánsdóttir, Marianne Nieuwenhuijze, Mika Gissler, Kristjana Einarsdóttir Tags: ORIGINAL RESEARCH ARTICLE Source Type: research