Core training for pain management and functional improvement in patients with patellofemoral pain syndrome: a systematic review and meta-analysis
CONCLUSIONS: Although training that includes trunk core is clearly superior to knee strengthening alone, the effectiveness of hip-knee training, which is also a core training program for pain and function, is more pronounced. The available evidence supports that hip-knee training is the most valuable treatment option for patients with PFP.PMID:38684137 | DOI:10.1097/PHM.0000000000002513 (Source: Health Physics)
Source: Health Physics - April 29, 2024 Category: Physics Authors: Yongshen Wang Hongpeng Li Di Zhang Tianyu Zhao Zhixiang Liu Jia Chen Meng Gong Juanhong Pan Li Lu Song Jin Source Type: research
A deep learning-based 3D Prompt-nnUnet model for automatic segmentation in brachytherapy of postoperative endometrial carcinoma
CONCLUSION: The Prompt-nnUnet architecture, particularly the LP, was highly consistent with ground truth (GT) in HR CTV or OAR autosegmentation, reducing interobserver variability and shortening treatment time.PMID:38682540 | DOI:10.1002/acm2.14371 (Source: Health Physics)
Source: Health Physics - April 29, 2024 Category: Physics Authors: Xian Xue Dazhu Liang Kaiyue Wang Jianwei Gao Jingjing Ding Fugen Zhou Juan Xu Hefeng Liu Quanfu Sun Ping Jiang Laiyuan Tao Wenzhao Shi Jinsheng Cheng Source Type: research
A deep learning-based 3D Prompt-nnUnet model for automatic segmentation in brachytherapy of postoperative endometrial carcinoma
CONCLUSION: The Prompt-nnUnet architecture, particularly the LP, was highly consistent with ground truth (GT) in HR CTV or OAR autosegmentation, reducing interobserver variability and shortening treatment time.PMID:38682540 | DOI:10.1002/acm2.14371 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - April 29, 2024 Category: Physics Authors: Xian Xue Dazhu Liang Kaiyue Wang Jianwei Gao Jingjing Ding Fugen Zhou Juan Xu Hefeng Liu Quanfu Sun Ping Jiang Laiyuan Tao Wenzhao Shi Jinsheng Cheng Source Type: research
Token Sparsification for Faster Medical Image Segmentation
Inf Process Med Imaging. 2023 Jun;13939:743-754. doi: 10.1007/978-3-031-34048-2_57. Epub 2023 Jun 8.ABSTRACTCan we use sparse tokens for dense prediction, e.g., segmentation? Although token sparsification has been applied to Vision Transformers (ViT) to accelerate classification, it is still unknown how to perform segmentation from sparse tokens. To this end, we reformulate segmentation as a sparse encoding → token completion → dense decoding (SCD) pipeline. We first empirically show that naïvely applying existing approaches from classification token pruning and masked image modeling (MIM) leads to failure and ineffic...
Source: Inf Process Med Imaging - April 29, 2024 Category: Radiology Authors: Lei Zhou Huidong Liu Joseph Bae Junjun He Dimitris Samaras Prateek Prasanna Source Type: research
Association between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, Canada
CMAJ. 2024 Apr 28;196(16):E547-E557. doi: 10.1503/cmaj.231419.ABSTRACTBACKGROUND: People with opioid use disorder (OUD) are at risk of premature death and can benefit from palliative care. We sought to compare palliative care provision for decedents with and without OUD.METHODS: We conducted a cohort study using health administrative databases in Ontario, Canada, to identify people who died between July 1, 2015, and Dec. 31, 2021. The exposure was OUD, defined as having emergency department visits, hospital admissions, or pharmacologic treatments suggestive of OUD within 3 years of death. Our primary outcome was receipt of...
Source: Canadian Medical Association Journal - April 29, 2024 Category: General Medicine Authors: Jenny Lau Mary M Scott Karl Everett Tara Gomes Peter Tanuseputro Sheila Jennings Rebecca Bagnarol Camilla Zimmermann Sarina R Isenberg Source Type: research
The false promise of firearms examination validation studies: Lay controls, simplistic comparisons, and the failure to soundly measure misidentification rates
This article therefore utilizes such a group, specifically 82 attorneys, as a post hoc control and juxtaposes their performance on a comparison set of cartridge case images from one commonly cited study (Duez et al. in J Forensic Sci. 2018;63:1069-1084) with that of the original participant pool of professionals. Despite lacking the kind of formalized training and experience common to the latter, our lay participants displayed an ability, generally, to distinguish between cartridge cases fired by the same versus different guns in the 327 comparisons they performed. And while their accuracy rates lagged substantially behind...
Source: Journal of Forensic Sciences - April 29, 2024 Category: Forensic Medicine Authors: Richard E Gutierrez Emily J Prokesch Source Type: research
Comparison of Novel Proteomic Expression Profiles for Radiation Exposure in Male and Female C57BL6 Mice
Radiat Res. 2024 Apr 30. doi: 10.1667/RADE-23-00180.1. Online ahead of print.ABSTRACTThere is a need for point-of-care diagnostics for future mass casualty events involving radiation exposure. The development of radiation exposure and dose prediction algorithms for biodosimetry is needed for screening of large populations during these scenarios, and exploration of the potential effects which sex, age, genetic heterogeneity, and physiological comorbidities may have on the utility of biodosimetry diagnostics is needed. In the current study, proteomic profiling was used to examine sex-specific differences in age-matched C57BL...
Source: Radiation Research - April 29, 2024 Category: Physics Authors: M Sproull Y Fan Q Chen D Meerzaman K Camphausen Source Type: research
Task-similarity is a crucial factor for few-shot meta-learning of structure-activity relationships
In this study, we assessed the effectiveness of two different meta-learning methods, namely model-agnostic meta-learning (MAML) and adaptive deep kernel fitting (ADKF), specifically in the regression setting. We investigated how factors such as dataset size and the similarity of training tasks impact predictability. The results indicate that ADKF significantly outperformed both MAML and a single-task baseline model on the inhibition data. However, the performance of ADKF varied across different test tasks. Our findings suggest that considerable enhancements in performance can be anticipated primarily when the task of inter...
Source: Chembiochem - April 29, 2024 Category: Biochemistry Authors: Alexander K ötter Stephan Allenspach Christoph Grebner Hans Matter Jan Hiss Gisbert Schneider Gerhard Hessler Source Type: research
Structurally diverse oxygen-containing aromatic compounds with anti-inflammatory activity from < em > Aspergillus < /em > sp. LY-1-2
Nat Prod Res. 2024 Apr 29:1-9. doi: 10.1080/14786419.2024.2347451. Online ahead of print.ABSTRACTThree isocoumarins, ascoisocoumarin A (1), embeurekol (2), and sclerotinin A (3), and five biosynthetically related derivatives, ascospinols A-C (4, 6, and 7), and talaflavuols C and B (5 and 8), together with twelve polyketides or terpenes (9-20) were isolated from the fungus Aspergillus sp. LY-1-2 inhabited in a sample of Cordyceps sp. Most of them belong to the family of oxygen-containing aromatic compounds and compounds 1, 4, 6, and 7 are previously undescribed compounds. Their planar structures were established by a combin...
Source: Natural Product Research - April 29, 2024 Category: Biochemistry Authors: Chu-Qiao Wang Jinzhi Pan Shuang-Zhi Yuan Chao Yuan Fei-Xiang Ji Dan Feng Xiao-Ping Peng Qian Luo Hong-Xiang Lou Gang Li Source Type: research
Bioinformatics Analysis Identifies Key Genes in the Effect of Resistance Training on Female Skeletal Muscle Aging
J Aging Phys Act. 2024 Apr 29:1-10. doi: 10.1123/japa.2023-0178. Online ahead of print.ABSTRACTResistance training is used to combat skeletal muscle function decline in older adults. Few studies have been designed specific for females, resulting in very limited treatment options for skeletal muscle atrophy in aging women. Here, we analyzed the gene expression profiles of skeletal muscle samples from sedentary young women, sedentary older women, and resistance-trained older women, using microarray data from public database. A total of 45 genes that were differentially expressed during female muscle aging and reversed by res...
Source: Journal of Aging and Physical Activity - April 29, 2024 Category: Geriatrics Authors: Jiacheng Ma Xiaoli Pang Ismail Laher Shunchang Li Source Type: research
Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis
CONCLUSION: The combined model, integrating both radiomics and clinical-radiologic characteristics, exhibited excellent performance in HCC with cirrhosis. The K-M curves assessing OS revealed statistically significant differences.PMID:38681988 | PMC:PMC11045480 | DOI:10.3748/wjg.v30.i15.2128 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Gui-Xiang Qian Zi-Ling Xu Yong-Hai Li Jian-Lin Lu Xiang-Yi Bu Ming-Tong Wei Wei-Dong Jia Source Type: research
Choriocapillaris Perfusion after 8 Weeks of High-Speed Circuit Training in Older Healthy Adults
CONCLUSION: CCD appeared to remain stable after 8 weeks of HSCT in healthy older individuals, possibly due to autoregulation. Further research with extended training may be necessary to verify these findings.PMID:38679899 | DOI:10.1080/02713683.2024.2346538 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Ava-Gaye Simms Joseph F Signorile Gustavo Rosa Gameiro Abdulrahman Mamoon Allaf Jianhua Wang Hong Jiang Source Type: research
Best practices for the dissemination and implementation of neuromuscular training injury prevention warm-ups in youth team sport: a systematic review
CONCLUSIONS: Workshops including supplementary resources supported the success of NMT programme implementation, however, few studies examined effectiveness. High-quality D&I studies are needed to optimise the translation of NMT programmes into routine practice in youth sport.PMID:38684329 | DOI:10.1136/bjsports-2023-106906 (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - April 29, 2024 Category: Sports Medicine Authors: Destiny Lutz Carla van den Berg Anu M R äisänen Isla J Shill Jemma Kim Kenzie Vaandering Alix Hayden Kati Pasanen Kathryn J Schneider Carolyn A Emery Oluwatoyosi B A Owoeye Source Type: research
"Emergency Room Incision and Drainage of Perirectal Abscess is Equivalent to Incision and Drainage in the Operating Room"
In this study, for patients presenting to the ED, bedside drainage was found to be an adequate management strategy to achieve complete drainage without a significant increase in the rate of complications when compared to operative drainage.PMID:38684322 | DOI:10.1177/00031348241248785 (Source: The American Surgeon)
Source: The American Surgeon - April 29, 2024 Category: Surgery Authors: Seija A Maniskas Mallory I Jebbia Dena Nasir Gabriel Akopian Howard S Kaufman Juliane Y Golan Source Type: research
Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis
CONCLUSION: The combined model, integrating both radiomics and clinical-radiologic characteristics, exhibited excellent performance in HCC with cirrhosis. The K-M curves assessing OS revealed statistically significant differences.PMID:38681988 | PMC:PMC11045480 | DOI:10.3748/wjg.v30.i15.2128 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Gui-Xiang Qian Zi-Ling Xu Yong-Hai Li Jian-Lin Lu Xiang-Yi Bu Ming-Tong Wei Wei-Dong Jia Source Type: research
