Region of interest optimization for radiation therapy of breast cancer
J Appl Clin Med Phys. 2021 Sep 20. doi: 10.1002/acm2.13410. Online ahead of print.ABSTRACTPURPOSE: The goal of this study was to investigate how the choice of the region of interest (ROI) affects the registration results of surface imaging for daily positioning of breast cancer patients.METHODS: The AlignRT system (VisionRT, London) and the XVI Cone beam CT (CBCT; Elekta, Stockholm) installed on two Versa HD linacs (Elekta) were used in this study, which included 28 patients (160 fractions). In the clinical workflow, patients were prepositioned with AlignRT and then shifted in 6 degrees of freedom (DOF) according to the CB...
Source: Journal of Applied Clinical Medical Physics - September 20, 2021 Category: Physics Authors: Tim-Oliver Sauer Oliver J Ott Godehard Lahmer Rainer Fietkau Christoph Bert Source Type: research

Region of interest optimization for radiation therapy of breast cancer
J Appl Clin Med Phys. 2021 Sep 20. doi: 10.1002/acm2.13410. Online ahead of print.ABSTRACTPURPOSE: The goal of this study was to investigate how the choice of the region of interest (ROI) affects the registration results of surface imaging for daily positioning of breast cancer patients.METHODS: The AlignRT system (VisionRT, London) and the XVI Cone beam CT (CBCT; Elekta, Stockholm) installed on two Versa HD linacs (Elekta) were used in this study, which included 28 patients (160 fractions). In the clinical workflow, patients were prepositioned with AlignRT and then shifted in 6 degrees of freedom (DOF) according to the CB...
Source: Journal of Applied Clinical Medical Physics - September 20, 2021 Category: Physics Authors: Tim-Oliver Sauer Oliver J Ott Godehard Lahmer Rainer Fietkau Christoph Bert Source Type: research

Initial analysis of the dosimetric benefit and clinical resource cost of CBCT-based online adaptive radiotherapy for patients with cancers of the cervix or rectum
CONCLUSIONS: Dosimetric benefits can be achieved with CBCT-based online ART that is amenable to conventional appointment slots. The clinical significance of these benefits remains to be determined. Managing contours was the primary factor affecting the total duration and is imperative for safe and effective adaptive radiotherapy.PMID:34529332 | DOI:10.1002/acm2.13425 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 16, 2021 Category: Physics Authors: Adam D Yock Mahmoud Ahmed Diandra Ayala-Peacock A Bapsi Chakravarthy Michael Price Source Type: research

Development of breast phantoms using a 3D printer and glandular dose evaluation
In this study, breast phantoms were fabricated by emulating glandular and adipose tissues separately using a three-dimensional (3D) printer. In addition, direct and quantitative glandular dose evaluations were performed. A quantitative method was developed to evaluate the glandular and adipose tissues separately when performing glandular dose evaluations. The variables used for glandular dose evaluation were breast thickness, glandular tissue ratio, and additional filter materials. The values obtained using a Monte Carlo simulation and those measured using a glass dosimeter were compared and analyzed. The analysis showed t...
Source: Journal of Applied Clinical Medical Physics - September 16, 2021 Category: Physics Authors: Dong-Yeon Lee Yong-In Jo Sung-Hee Yang Source Type: research

Dose rate correction for a silicon diode detector array
CONCLUSIONS: The instantaneous DRD was identified as the prevailing effect on the diode sensitivity. We developed and validated a method to correct this behavior. The number of falsely not passed treatment plans could be considerably reduced.PMID:34519437 | DOI:10.1002/acm2.13409 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 14, 2021 Category: Physics Authors: Andreas J äger Sonja Wegener Otto A Sauer Source Type: research

Dose rate correction for a silicon diode detector array
CONCLUSIONS: The instantaneous DRD was identified as the prevailing effect on the diode sensitivity. We developed and validated a method to correct this behavior. The number of falsely not passed treatment plans could be considerably reduced.PMID:34519437 | DOI:10.1002/acm2.13409 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 14, 2021 Category: Physics Authors: Andreas J äger Sonja Wegener Otto A Sauer Source Type: research

Dose rate correction for a silicon diode detector array
CONCLUSIONS: The instantaneous DRD was identified as the prevailing effect on the diode sensitivity. We developed and validated a method to correct this behavior. The number of falsely not passed treatment plans could be considerably reduced.PMID:34519437 | DOI:10.1002/acm2.13409 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 14, 2021 Category: Physics Authors: Andreas J äger Sonja Wegener Otto A Sauer Source Type: research

Dose rate correction for a silicon diode detector array
CONCLUSIONS: The instantaneous DRD was identified as the prevailing effect on the diode sensitivity. We developed and validated a method to correct this behavior. The number of falsely not passed treatment plans could be considerably reduced.PMID:34519437 | DOI:10.1002/acm2.13409 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 14, 2021 Category: Physics Authors: Andreas J äger Sonja Wegener Otto A Sauer Source Type: research

Dose rate correction for a silicon diode detector array
CONCLUSIONS: The instantaneous DRD was identified as the prevailing effect on the diode sensitivity. We developed and validated a method to correct this behavior. The number of falsely not passed treatment plans could be considerably reduced.PMID:34519437 | DOI:10.1002/acm2.13409 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 14, 2021 Category: Physics Authors: Andreas J äger Sonja Wegener Otto A Sauer Source Type: research

Deformable registration of chest CT images using a 3D convolutional neural network based on unsupervised learning
CONCLUSIONS: In this study, we have shown that the proposed method was efficient in 3D chest image registration. The promising results demonstrated that our method showed strong robustness in the deformable registration of 3D chest CT images.PMID:34505341 | DOI:10.1002/acm2.13392 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Yongnan Zheng Shan Jiang Zhiyong Yang Source Type: research

A case study of cost-benefit analysis in occupational radiological protection within the healthcare system of  Sweden
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13421. Online ahead of print.ABSTRACTThe aim of the present study was to demonstrate cases of cost-benefit analysis within healthcare, of how economic factors can be considered in occupational radiological protection, in agreement with the as low as reasonably achievable principle and present Swedish legislations. In the first part of the present study, a comparison of examples within health economics used by authorities and institutes in Sweden was made. The comparison focused on value of a statistical life, quality-adjusted life year, and monetary cost assigned to a un...
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andreas Engstr öm Mats Isaksson Reza Javid Charlotta Lundh Magnus B åth Source Type: research

Longitudinal assessment of quality assurance measurements in a 1.5T MR-linac: Part I-Linear accelerator
CONCLUSION: The MR-linac operates within the guidelines of current recommendations for linear accelerator performance, stability, and safety. The analysis of the data supports the recently published guidance in establishing clinically acceptable tolerance levels for relative and absolute measurements.PMID:34505349 | DOI:10.1002/acm2.13418 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Ergys Subashi Seng Boh Lim Xesus Gonzalez Neelam Tyagi Source Type: research

Human factor associations with safety events in radiation therapy
CONCLUSION: An application of the HFACS to incident learning reports revealed relationships between human contributing factors and radiotherapy errors. Safety improvement efforts should include supervisory influences as they affect risk and error. An association between skill-based and treatment planning errors showed a need for more mindfulness in this increasingly automated process. An association between decision and QA errors revealed a need for improved education in this area. These and other findings can be used to strategically advance safety.PMID:34505353 | DOI:10.1002/acm2.13420 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Sheri M Weintraub Bill J Salter C Lynn Chevalier Sarah Ransdell Source Type: research

A framework for developing community-focused medical physics outreach programs
CONCLUSIONS: Our medical physics outreach program demonstrates a means of increasing awareness and interest around medical physics, particularly for underrepresented individuals. This article addresses gaps in the literature for how to create and implement effective, community-focused medical physics outreach programs.PMID:34505354 | DOI:10.1002/acm2.13413 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andrew P Santoso Sydney Jupitz Christie Lin Source Type: research

Are you ready for a cyberattack?
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13422. Online ahead of print.NO ABSTRACTPMID:34505355 | DOI:10.1002/acm2.13422 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Daniel W Pinkham Ina M Sala Emilie T Soisson Brian Wang Matthew A Deeley Source Type: research

Comparison of combinations of irradiation techniques and jaw conditions in intensity-modulated radiotherapy for lung cancer
CONCLUSION: Based on the dosimetric findings and considering clinical data published on lung and heart side effects, we propose recommendations on the preferred treatment technique based on tumor location and pulmonary function. For central lung cancer with normal pulmonary function, we advise JT-VMAT techniques. Conversely, for central lung cancer with poor pulmonary function, we recommend JA-IMRT techniques. We advocate JA-IMRT for peripheral E lung cancer. For peripheral N lung cancer, JT-VMAT techniques are strongly recommended.PMID:34505397 | DOI:10.1002/acm2.13416 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Qinghe Peng Junyue Shi Jun Zhang Qiwen Li Zhenghuan Li Qingyuan Zhang Yinglin Peng Li Chen Source Type: research

Deformable registration of chest CT images using a 3D convolutional neural network based on unsupervised learning
CONCLUSIONS: In this study, we have shown that the proposed method was efficient in 3D chest image registration. The promising results demonstrated that our method showed strong robustness in the deformable registration of 3D chest CT images.PMID:34505341 | DOI:10.1002/acm2.13392 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Yongnan Zheng Shan Jiang Zhiyong Yang Source Type: research

A case study of cost-benefit analysis in occupational radiological protection within the healthcare system of  Sweden
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13421. Online ahead of print.ABSTRACTThe aim of the present study was to demonstrate cases of cost-benefit analysis within healthcare, of how economic factors can be considered in occupational radiological protection, in agreement with the as low as reasonably achievable principle and present Swedish legislations. In the first part of the present study, a comparison of examples within health economics used by authorities and institutes in Sweden was made. The comparison focused on value of a statistical life, quality-adjusted life year, and monetary cost assigned to a un...
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andreas Engstr öm Mats Isaksson Reza Javid Charlotta Lundh Magnus B åth Source Type: research

Longitudinal assessment of quality assurance measurements in a 1.5T MR-linac: Part I-Linear accelerator
CONCLUSION: The MR-linac operates within the guidelines of current recommendations for linear accelerator performance, stability, and safety. The analysis of the data supports the recently published guidance in establishing clinically acceptable tolerance levels for relative and absolute measurements.PMID:34505349 | DOI:10.1002/acm2.13418 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Ergys Subashi Seng Boh Lim Xesus Gonzalez Neelam Tyagi Source Type: research

Human factor associations with safety events in radiation therapy
CONCLUSION: An application of the HFACS to incident learning reports revealed relationships between human contributing factors and radiotherapy errors. Safety improvement efforts should include supervisory influences as they affect risk and error. An association between skill-based and treatment planning errors showed a need for more mindfulness in this increasingly automated process. An association between decision and QA errors revealed a need for improved education in this area. These and other findings can be used to strategically advance safety.PMID:34505353 | DOI:10.1002/acm2.13420 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Sheri M Weintraub Bill J Salter C Lynn Chevalier Sarah Ransdell Source Type: research

A framework for developing community-focused medical physics outreach programs
CONCLUSIONS: Our medical physics outreach program demonstrates a means of increasing awareness and interest around medical physics, particularly for underrepresented individuals. This article addresses gaps in the literature for how to create and implement effective, community-focused medical physics outreach programs.PMID:34505354 | DOI:10.1002/acm2.13413 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andrew P Santoso Sydney Jupitz Christie Lin Source Type: research

Are you ready for a cyberattack?
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13422. Online ahead of print.NO ABSTRACTPMID:34505355 | DOI:10.1002/acm2.13422 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Daniel W Pinkham Ina M Sala Emilie T Soisson Brian Wang Matthew A Deeley Source Type: research

Comparison of combinations of irradiation techniques and jaw conditions in intensity-modulated radiotherapy for lung cancer
CONCLUSION: Based on the dosimetric findings and considering clinical data published on lung and heart side effects, we propose recommendations on the preferred treatment technique based on tumor location and pulmonary function. For central lung cancer with normal pulmonary function, we advise JT-VMAT techniques. Conversely, for central lung cancer with poor pulmonary function, we recommend JA-IMRT techniques. We advocate JA-IMRT for peripheral E lung cancer. For peripheral N lung cancer, JT-VMAT techniques are strongly recommended.PMID:34505397 | DOI:10.1002/acm2.13416 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Qinghe Peng Junyue Shi Jun Zhang Qiwen Li Zhenghuan Li Qingyuan Zhang Yinglin Peng Li Chen Source Type: research

Deformable registration of chest CT images using a 3D convolutional neural network based on unsupervised learning
CONCLUSIONS: In this study, we have shown that the proposed method was efficient in 3D chest image registration. The promising results demonstrated that our method showed strong robustness in the deformable registration of 3D chest CT images.PMID:34505341 | DOI:10.1002/acm2.13392 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Yongnan Zheng Shan Jiang Zhiyong Yang Source Type: research

A case study of cost-benefit analysis in occupational radiological protection within the healthcare system of  Sweden
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13421. Online ahead of print.ABSTRACTThe aim of the present study was to demonstrate cases of cost-benefit analysis within healthcare, of how economic factors can be considered in occupational radiological protection, in agreement with the as low as reasonably achievable principle and present Swedish legislations. In the first part of the present study, a comparison of examples within health economics used by authorities and institutes in Sweden was made. The comparison focused on value of a statistical life, quality-adjusted life year, and monetary cost assigned to a un...
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andreas Engstr öm Mats Isaksson Reza Javid Charlotta Lundh Magnus B åth Source Type: research

Longitudinal assessment of quality assurance measurements in a 1.5T MR-linac: Part I-Linear accelerator
CONCLUSION: The MR-linac operates within the guidelines of current recommendations for linear accelerator performance, stability, and safety. The analysis of the data supports the recently published guidance in establishing clinically acceptable tolerance levels for relative and absolute measurements.PMID:34505349 | DOI:10.1002/acm2.13418 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Ergys Subashi Seng Boh Lim Xesus Gonzalez Neelam Tyagi Source Type: research

Human factor associations with safety events in radiation therapy
CONCLUSION: An application of the HFACS to incident learning reports revealed relationships between human contributing factors and radiotherapy errors. Safety improvement efforts should include supervisory influences as they affect risk and error. An association between skill-based and treatment planning errors showed a need for more mindfulness in this increasingly automated process. An association between decision and QA errors revealed a need for improved education in this area. These and other findings can be used to strategically advance safety.PMID:34505353 | DOI:10.1002/acm2.13420 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Sheri M Weintraub Bill J Salter C Lynn Chevalier Sarah Ransdell Source Type: research

A framework for developing community-focused medical physics outreach programs
CONCLUSIONS: Our medical physics outreach program demonstrates a means of increasing awareness and interest around medical physics, particularly for underrepresented individuals. This article addresses gaps in the literature for how to create and implement effective, community-focused medical physics outreach programs.PMID:34505354 | DOI:10.1002/acm2.13413 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Andrew P Santoso Sydney Jupitz Christie Lin Source Type: research

Are you ready for a cyberattack?
J Appl Clin Med Phys. 2021 Sep 10. doi: 10.1002/acm2.13422. Online ahead of print.NO ABSTRACTPMID:34505355 | DOI:10.1002/acm2.13422 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Daniel W Pinkham Ina M Sala Emilie T Soisson Brian Wang Matthew A Deeley Source Type: research

Comparison of combinations of irradiation techniques and jaw conditions in intensity-modulated radiotherapy for lung cancer
CONCLUSION: Based on the dosimetric findings and considering clinical data published on lung and heart side effects, we propose recommendations on the preferred treatment technique based on tumor location and pulmonary function. For central lung cancer with normal pulmonary function, we advise JT-VMAT techniques. Conversely, for central lung cancer with poor pulmonary function, we recommend JA-IMRT techniques. We advocate JA-IMRT for peripheral E lung cancer. For peripheral N lung cancer, JT-VMAT techniques are strongly recommended.PMID:34505397 | DOI:10.1002/acm2.13416 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 10, 2021 Category: Physics Authors: Qinghe Peng Junyue Shi Jun Zhang Qiwen Li Zhenghuan Li Qingyuan Zhang Yinglin Peng Li Chen Source Type: research

Predicting the effect of indirect cell kill in the treatment of multiple brain metastases via single-isocenter/multitarget volumetric modulated arc therapy stereotactic radiosurgery
CONCLUSIONS: Radiosurgery of m-bm using SIMT-VMAT treatments have shown positive clinical outcomes even with small residual patient setup errors. These clinical outcomes, while largely due to DCK, may also potentially be due to the ICK. Potential mechanisms, such as devascularization and/or radiation-induced intratumor immune enhancement, should be explored to provide a better understanding of the radiobiological response of stereotactic radiosurgery of m-bm using a SIMT-VMAT plan.PMID:34498359 | DOI:10.1002/acm2.13400 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 9, 2021 Category: Physics Authors: Allison N Palmiero Denise Fabian Marcus E Randall William Clair Damodar Pokhrel Source Type: research

Hybrid Tomo-Helical and Tomo-Direct radiotherapy for localized prostate cancer
J Appl Clin Med Phys. 2021 Sep 8. doi: 10.1002/acm2.13406. Online ahead of print.ABSTRACTPURPOSE: The aim of the study is to present a new planning approach to provide better planning target volume (PTV) coverage and reduce bladder and rectum dose with hybrid Tomo-Helical (TH)/Tomo-Direct (TD) radiotherapy (RT) for localized prostate cancer (LPC).METHODS: Twenty-five LPC patients were included in this retrospective study. TH plans, TD plans, and hybrid TH/TD plans were created. Lateral beams were used for the hybrid TD plan and the prescribed dose was 70 Gy in 28 fractions (hybrid plans were combined 45 Gy/ 18 fxs for TH a...
Source: Journal of Applied Clinical Medical Physics - September 9, 2021 Category: Physics Authors: Sibel Karaca Timur Koca İsmail Hakkı Sarpün Nina Tun çel Aylin Fidan Korcum Şahin Source Type: research

Predicting the effect of indirect cell kill in the treatment of multiple brain metastases via single-isocenter/multitarget volumetric modulated arc therapy stereotactic radiosurgery
CONCLUSIONS: Radiosurgery of m-bm using SIMT-VMAT treatments have shown positive clinical outcomes even with small residual patient setup errors. These clinical outcomes, while largely due to DCK, may also potentially be due to the ICK. Potential mechanisms, such as devascularization and/or radiation-induced intratumor immune enhancement, should be explored to provide a better understanding of the radiobiological response of stereotactic radiosurgery of m-bm using a SIMT-VMAT plan.PMID:34498359 | DOI:10.1002/acm2.13400 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 9, 2021 Category: Physics Authors: Allison N Palmiero Denise Fabian Marcus E Randall William Clair Damodar Pokhrel Source Type: research

Hybrid Tomo-Helical and Tomo-Direct radiotherapy for localized prostate cancer
J Appl Clin Med Phys. 2021 Sep 8. doi: 10.1002/acm2.13406. Online ahead of print.ABSTRACTPURPOSE: The aim of the study is to present a new planning approach to provide better planning target volume (PTV) coverage and reduce bladder and rectum dose with hybrid Tomo-Helical (TH)/Tomo-Direct (TD) radiotherapy (RT) for localized prostate cancer (LPC).METHODS: Twenty-five LPC patients were included in this retrospective study. TH plans, TD plans, and hybrid TH/TD plans were created. Lateral beams were used for the hybrid TD plan and the prescribed dose was 70 Gy in 28 fractions (hybrid plans were combined 45 Gy/ 18 fxs for TH a...
Source: Journal of Applied Clinical Medical Physics - September 9, 2021 Category: Physics Authors: Sibel Karaca Timur Koca İsmail Hakkı Sarpün Nina Tun çel Aylin Fidan Korcum Şahin Source Type: research

Reconstruction of volume averaging effect-free continuous photon beam profiles from discrete ionization chamber array measurements using a machine learning technique
CONCLUSIONS: This study demonstrated the feasibility of using simple ANNs to reconstruct VAE-free continuous photon beam profiles from discrete ICP measurements. A combined ANN can restore the penumbra of in- and cross-plane beam profiles of various fields at different depths.PMID:34486800 | DOI:10.1002/acm2.13411 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 6, 2021 Category: Physics Authors: Karl Mund Luke Maloney Bo Lu Jian Wu Jonathan Li Chihray Liu Guanghua Yan Source Type: research

Dosimetry verification of three-dimensional printed polylactic acid template-guided precision < sup > 125 < /sup > I seed implantation for lung cancer using a desktop three-dimensional printer
CONCLUSIONS: The preoperative TPS plan for the experimental group guided by the PLA template was almost the same as that for the final guided particle implantation. The dose parameters in the experimental group were also better than those in the traditional group, making the use of the presented PLA template more efficient for clinical applications.PMID:34487634 | DOI:10.1002/acm2.13419 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 6, 2021 Category: Physics Authors: Xiaoyan Han Shu Fang Rui Sheng Yi Wang Jinhua Zhou Jiong Wang Source Type: research

Reconstruction of volume averaging effect-free continuous photon beam profiles from discrete ionization chamber array measurements using a machine learning technique
CONCLUSIONS: This study demonstrated the feasibility of using simple ANNs to reconstruct VAE-free continuous photon beam profiles from discrete ICP measurements. A combined ANN can restore the penumbra of in- and cross-plane beam profiles of various fields at different depths.PMID:34486800 | DOI:10.1002/acm2.13411 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 6, 2021 Category: Physics Authors: Karl Mund Luke Maloney Bo Lu Jian Wu Jonathan Li Chihray Liu Guanghua Yan Source Type: research

Dosimetry verification of three-dimensional printed polylactic acid template-guided precision < sup > 125 < /sup > I seed implantation for lung cancer using a desktop three-dimensional printer
CONCLUSIONS: The preoperative TPS plan for the experimental group guided by the PLA template was almost the same as that for the final guided particle implantation. The dose parameters in the experimental group were also better than those in the traditional group, making the use of the presented PLA template more efficient for clinical applications.PMID:34487634 | DOI:10.1002/acm2.13419 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 6, 2021 Category: Physics Authors: Xiaoyan Han Shu Fang Rui Sheng Yi Wang Jinhua Zhou Jiong Wang Source Type: research

Image-guided volumetric-modulated arc therapy of total body irradiation: An efficient workflow from simulation to delivery
This study presents a robust planning technique with image-guided delivery to improve dose delivery accuracy. In addition, a streamlined sim-to-treat workflow with automatic scripts is proposed to reduce planning time.MATERIALS: Twenty-five patients were included in this study. Patients were scanned in supine head-first and feet-first directions. An automatic workflow was used to (1) create a whole-body CT by registering two CT scans, (2) contour lungs, kidneys, and planning target volume (PTV), (3) divide PTV into multiple sub-targets for planning, and (4) place isocenters. Treatment planning included feathered AP/PA beam...
Source: Journal of Applied Clinical Medical Physics - September 4, 2021 Category: Physics Authors: Bingqi Guo Cherian Sheen Erin Murphy Anthony Magnelli Lan Lu YoungBin Cho Peng Qi Navneet S Majhail Ping Xia Source Type: research

Detection of acute myocarditis using T1 and T2 mapping cardiovascular magnetic resonance: A systematic review and meta-analysis
This study was aimed to systematically review the existing literature and explore more the diagnostic value of T1 and T2 mapping in acute myocarditis.METHODS: Studies were searched from five electronic databases. Sensitivity, specificity, diagnostic odds ratio (DOR), and summary receiver operating characteristic curves (SROC) were calculated to present diagnostic performance. A meta-regression and subgroup analysis was performed based on validation (endomyocardial biopsy [EMB] vs. clinical criteria).RESULTS: A total of 10 studies were included, with 400 myocarditis patients and 266 controls. Native T1, T2, and extracellula...
Source: Journal of Applied Clinical Medical Physics - September 4, 2021 Category: Physics Authors: Zhi Jia Lihong Wang Yanqing Jia Jun Liu Hong Zhao Liwei Huo Binbin Zheng Source Type: research

Response: Potential dose variability for small-field plans delivered with Elekta Agility collimators
J Appl Clin Med Phys. 2021 Sep 4. doi: 10.1002/acm2.13414. Online ahead of print.NO ABSTRACTPMID:34480834 | DOI:10.1002/acm2.13414 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 4, 2021 Category: Physics Authors: Friedlieb H Lorenz Matthew I Paris Source Type: research

Nontoxic electron collimators
CONCLUSIONS: Both flexible tungsten-silicone and 3D printed cutouts were found to be feasible for clinical use. The flexible tungsten-silicone was of adequate density, flexibility, and uniformity to serve as skin shields for electron therapy. The 3D printed cutouts were dosimetrically equivalent to standard cerrobend cutouts and were robust enough for handling in the clinical environment.PMID:34480841 | DOI:10.1002/acm2.13398 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 4, 2021 Category: Physics Authors: Dylan Yamabe Breitkreutz Lawrie Skinner Stephanie Lo Amy Yu Source Type: research

Design and implementation of a practical quality control program for dual-energy CT
J Appl Clin Med Phys. 2021 Sep 2. doi: 10.1002/acm2.13396. Online ahead of print.ABSTRACTA novel routine dual-energy computed tomography (DECT) quality control (QC) program was developed to address the current deficiency of routine QC for this technology. The dual-energy quality control (DEQC) program features (1) a practical phantom with clinically relevant materials and concentrations, (2) a clinically relevant acquisition, reconstruction, and postprocessing protocol, and (3) a fully automated analysis software to extract quantitative data for database storage and trend analysis. The phantom, designed for easy set up for...
Source: Journal of Applied Clinical Medical Physics - September 2, 2021 Category: Physics Authors: Crystal A Green Justin B Solomon Kenneth J Ruchala Ehsan Samei Source Type: research

Mathematical estimation of half-value layer thicknesses
CONCLUSION: The HVL is an essential component in the evaluation of the quality of an x-ray beam. However, its measurement could occasionally be challenging, time-consuming, or uncertain due to some technical difficulties. Although the scope of this study is not to undermine the value of conventional and widely accepted practice to determine the HVL thickness, the introduced method provides the fast, more convenient, and comparably reliable technique to estimate the HVL, QVL, and TVL by employing the given x-ray spectrum.PMID:34469057 | DOI:10.1002/acm2.13385 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - September 1, 2021 Category: Physics Authors: Farid H Omoumi Xizeng Wu Muhammad U Ghani Molly D Wong Yuhua Li Hong Liu Source Type: research

A bibliometric of publication trends in medical image segmentation: Quantitative and qualitative analysis
CONCLUSIONS: Through this bibliometric research work, the research hotspot in the medical image segmentation field is uncovered and can point to future research in the field. It can be expected that more researchers will focus their work on deep learning neural network-based medical image segmentation.PMID:34453471 | DOI:10.1002/acm2.13394 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Bin Zhang Bahbibi Rahmatullah Shir Li Wang Guangnan Zhang Huan Wang Nader Ale Ebrahim Source Type: research

Fluid-based augmentation of magnetic resonance visualization of interventional devices
J Appl Clin Med Phys. 2021 Aug 28. doi: 10.1002/acm2.13407. Online ahead of print.ABSTRACTPURPOSE: To evaluate the transient artifact augmentation of microtubes in magnetic resonance imaging by fluid injection.METHODS: Twenty-one fluorinated ethylene propylene catheters (inner diameter 760 μm) were filled with three different contrast media at various concentrations (Ferucarbotran, Resovist®, Bayer Schering Pharma; Manganese dichloride, MnCl2, Sigma-Aldrich; Gadobutrol, Gadovist®, Bayer Schering Pharma). Artifact appearance was determined in an ex vivo phantom at 1.5 T using three different sequences: T1-weighte...
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Jens K übler Petros Martirosian Johann Jacoby Georg Gohla Moritz T Winkelmann Konstantin Nikolaou R üdiger Hoffmann Source Type: research

A novel angular dependency model for MatriXX response and its application to true composite dose verification for IMRT plans
CONCLUSION: The proposed model for angular dependent MatriXX response is necessary and effective. Dose verification using MatriXX with angular-model-based approach is acceptable for true composite beam IMRT plans with required accuracy to simplify patient specific QA.PMID:34453876 | DOI:10.1002/acm2.13405 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Yin Zhou Jiugao Sang Haibo Chen Meng Zhu He Wang Shuwei Zhai Lina Lu Hui Liu Zhengfei Zhu Zhouguang Hui Jianrong Dai Jian Huan Source Type: research

A bibliometric of publication trends in medical image segmentation: Quantitative and qualitative analysis
CONCLUSIONS: Through this bibliometric research work, the research hotspot in the medical image segmentation field is uncovered and can point to future research in the field. It can be expected that more researchers will focus their work on deep learning neural network-based medical image segmentation.PMID:34453471 | DOI:10.1002/acm2.13394 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Bin Zhang Bahbibi Rahmatullah Shir Li Wang Guangnan Zhang Huan Wang Nader Ale Ebrahim Source Type: research

Fluid-based augmentation of magnetic resonance visualization of interventional devices
J Appl Clin Med Phys. 2021 Aug 28. doi: 10.1002/acm2.13407. Online ahead of print.ABSTRACTPURPOSE: To evaluate the transient artifact augmentation of microtubes in magnetic resonance imaging by fluid injection.METHODS: Twenty-one fluorinated ethylene propylene catheters (inner diameter 760 μm) were filled with three different contrast media at various concentrations (Ferucarbotran, Resovist®, Bayer Schering Pharma; Manganese dichloride, MnCl2, Sigma-Aldrich; Gadobutrol, Gadovist®, Bayer Schering Pharma). Artifact appearance was determined in an ex vivo phantom at 1.5 T using three different sequences: T1-weighte...
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Jens K übler Petros Martirosian Johann Jacoby Georg Gohla Moritz T Winkelmann Konstantin Nikolaou R üdiger Hoffmann Source Type: research

A novel angular dependency model for MatriXX response and its application to true composite dose verification for IMRT plans
CONCLUSION: The proposed model for angular dependent MatriXX response is necessary and effective. Dose verification using MatriXX with angular-model-based approach is acceptable for true composite beam IMRT plans with required accuracy to simplify patient specific QA.PMID:34453876 | DOI:10.1002/acm2.13405 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - August 28, 2021 Category: Physics Authors: Yin Zhou Jiugao Sang Haibo Chen Meng Zhu He Wang Shuwei Zhai Lina Lu Hui Liu Zhengfei Zhu Zhouguang Hui Jianrong Dai Jian Huan Source Type: research