Review of radiomics and radiogenomics and big data in radiation oncology.
PMID: 32643318 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - July 9, 2020 Category: Physics Authors: Zheng D Tags: J Appl Clin Med Phys Source Type: research

Capacitive monitoring system for real-time respiratory motion monitoring during radiation therapy.
CONCLUSION: This novel technology permits sensing of both free-breathing and breath-hold respiratory motion. It provides data comparable to the RPM system but without the need for an IR tracking camera in the treatment room or use of reflective markers on the patient. PMID: 32643322 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - July 9, 2020 Category: Physics Authors: Sadeghi P, Moran K, Robar JL Tags: J Appl Clin Med Phys Source Type: research

Implementation and validation of an in-house geometry optimization software for SRS VMAT planning of multiple cranial metastases.
ng;M Abstract PURPOSE: The implementation and evaluation of an in-house developed geometry optimization (GO) software are described. The GO script provides optimal lesion clustering, isocenter placement, and collimator angle of each arc for cranial multi-lesion stereotactic radiosurgery (SRS) volumetric modulated arc therapy (VMAT) planning. MATERIALS AND METHODS: An Eclipse-plugin program was developed to facilitate automatic plan geometry generation for multiple metastases SRS VMAT plans. A mixed, semi-supervised exhaustive and k-means clustering method is used to group lesions and place isocenters. The sum...
Source: Journal of Applied Clinical Medical Physics - July 6, 2020 Category: Physics Authors: Kuo L, Zhang P, Pham H, Ballangrud ÅM Tags: J Appl Clin Med Phys Source Type: research

Prediction of conical collimator collision for stereotactic radiosurgery.
In conclusion, the in-house software was able to calculate the minimum clearance distance with
Source: Journal of Applied Clinical Medical Physics - July 6, 2020 Category: Physics Authors: Park J, McDermott R, Kim S, Huq MS Tags: J Appl Clin Med Phys Source Type: research

Notes on cost benefit of COVID-19 lockdown.
PMID: 32619322 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - July 3, 2020 Category: Physics Authors: Mills M, Allen MB Tags: J Appl Clin Med Phys Source Type: research

Reducing contrast dose using virtual monoenergetic imaging for aortic CTA.
Abstract Three-dimensional computed tomographic angiography (3D-CTA) is widely used to evaluate the inner diameters of vessels and the anatomical vascular structure prior to endoscopic aortic surgery or transcatheter valve implantation. Virtual monoenergetic imaging (VMI) is a new application in dual-energy CT (DECT). We evaluated the potential for contrast dose reduction in preoperative aortic CTA using VMI. To evaluate performance in terms of image quality and vessel shape, we quantified the contrast-to-noise ratio (CNR) and the vessel diameter using a cylinder phantom we developed, and used volume rendering to ...
Source: Journal of Applied Clinical Medical Physics - July 2, 2020 Category: Physics Authors: Yoshida R, Usui K, Katsunuma Y, Honda H, Hatakeyama K Tags: J Appl Clin Med Phys Source Type: research

Performances of the beam monitoring system and quality assurance equipment for the HIMM of carbon-ion therapy.
CONCLUSIONS: The beam-monitoring system (BMS) and quality-assurance equipment (QAE) have been installed and run successfully within HIMM for two years and are associated with the HIMM treatment system to deliver the right dose to the correct position precisely. Furthermore, the daily QA task is simplified by it. Above all, the system has passed the performance test of the China Food and Drug Administration (CFDA). PMID: 32614149 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - July 2, 2020 Category: Physics Authors: Wei K, Xu Z, Mao R, Zhao Z, Zhao T, She Q, Kang X, Wang J, Li S, Li M, Song K, Yang H, Duan L Tags: J Appl Clin Med Phys Source Type: research

Continuous real time 3D motion reproduction using dynamic MRI and precomputed 4DCT deformation fields.
Abstract Radiotherapy of mobile tumors requires specific imaging tools and models to reduce the impact of motion on the treatment. Online continuous nonionizing imaging has become possible with the recent development of magnetic resonance imaging devices combined with linear accelerators. This opens the way to new guided treatment methods based on the real-time tracking of anatomical motion. In such devices, 2D fast MR-images are well-suited to capture and predict the real-time motion of the tumor. To be used effectively in an adaptive radiotherapy, these MR images have to be combined with X-ray images such as CT,...
Source: Journal of Applied Clinical Medical Physics - July 2, 2020 Category: Physics Authors: Dasnoy-Sumell D, Souris K, Van Ooteghem G, Macq B Tags: J Appl Clin Med Phys Source Type: research

Automated and robust beam data validation of a preconfigured ring gantry linear accelerator using a 1D tank with synchronized beam delivery and couch motions.
Abstract PURPOSE: To develop an efficient and automated methodology for beam data validation for a preconfigured ring gantry linear accelerator using scripting and a one-dimensional (1D) tank with automated couch motions. MATERIALS AND METHODS: Using an application programming interface, a program was developed to allow the user to choose a set of beam data to validate with measurement. Once selected the program generates a set of instructions for radiation delivery with synchronized couch motions for the linear accelerator in the form of an extensible markup language (XML) file to be delivered on the ring ga...
Source: Journal of Applied Clinical Medical Physics - July 2, 2020 Category: Physics Authors: Knutson NC, Schmidt MC, Reynoso FJ, Hao Y, Mazur TR, Laugeman E, Hugo G, Mutic S, Li HH, Ngwa W, Cai B, Sajo E Tags: J Appl Clin Med Phys Source Type: research

3D-printed headrest for frameless Gamma Knife radiosurgery: Design and validation.
CONCLUSIONS: We designed and validated a 3D-printed headrest for immobilizing patients undergoing frameless Gamma Knife SRS. PMID: 32603542 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 30, 2020 Category: Physics Authors: Baltz GC, Briere T, Luo D, Howell RM, Krafft S, Han EY Tags: J Appl Clin Med Phys Source Type: research

In search of a one plan solution for VMAT post-mastectomy chest wall irradiation.
CONCLUSIONS: Results of this work allow for consideration of different bolus thicknesses, materials, and usage schedules based on desired skin dose and choice of either tangents or an arc beam techniques. PMID: 32592451 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 27, 2020 Category: Physics Authors: Monajemi TT, Oliver PAK, Day A, Yewondwossen M Tags: J Appl Clin Med Phys Source Type: research

Surface-guided tomotherapy improves positioning and reduces treatment time: A retrospective analysis of 16  835 treatment fractions.
In this study, we have quantified the setup deviation and time gain when using fast surface scanning for daily setup/positioning with weekly megavoltage computed tomography (MVCT) and compared it to daily MVCT. METHODS: A total of 16 835 treatment fractions were analyzed, treated, and positioned using our TomoTherapy HD (Accuray Inc., Madison, USA) installed with a Sentinel optical surface scanning system (C-RAD Positioning AB, Uppsala, Sweden). Patients were positioned using in-room lasers, surface scanning and MVCT for the first three fractions. For the remaining fractions, in-room laser was used for setup foll...
Source: Journal of Applied Clinical Medical Physics - June 26, 2020 Category: Physics Authors: Haraldsson A, Ceberg S, Ceberg C, Bäck S, Engelholm S, Engström PE Tags: J Appl Clin Med Phys Source Type: research

Using failure mode and effects analysis (FMEA) to generate an initial plan check checklist for improved safety in radiation treatment.
CONCLUSION: The FMEA proved to be a valuable tool for identifying vulnerabilities in our workflow and processes in generating a treatment plan and subsequently a new, more effective initial plan checklist was created. PMID: 32583912 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 25, 2020 Category: Physics Authors: Rassiah P, Su FF, Huang YJ, Spitznagel D, Sarkar V, Szegedi MW, Zhao H, Paxton AB, Nelson G, Salter BJ Tags: J Appl Clin Med Phys Source Type: research

A study of the interplay effect for VMAT SBRT using a four-axes motion phantom.
CONCLUSIONS: In our clinical context, treating lung and liver lesions using VMAT SBRT is reasonable. The interplay effect was moderated and acceptable in all simulated situations. PMID: 32573908 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 23, 2020 Category: Physics Authors: Leste J, Medjahed I, Arnaud FX, Ferrand R, Franceries X, Bardies M, Simon L Tags: J Appl Clin Med Phys Source Type: research

Magnetic resonance safety assessment of a new trend: magnetic eyelashes.
PMID: 32562340 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 20, 2020 Category: Physics Authors: Eldeniz C, Andrews T, Krishnamurthy U, Aljaafari L, Foster G, Benzinger TLS, An H, Woodard PK Tags: J Appl Clin Med Phys Source Type: research

A collision prediction framework for noncoplanar radiotherapy planning and delivery.
CONCLUSION: The feasibility of developing a CPS using geometric models and standard vector algebra has been investigated. This study outlines a framework for potential clinical implementation of a CPS for noncoplanar radiotherapy. PMID: 32559004 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 19, 2020 Category: Physics Authors: Islam N, Kilian-Meneghin J, deBoer S, Podgorsak M Tags: J Appl Clin Med Phys Source Type: research

Boosting radiotherapy dose calculation accuracy with deep learning.
Abstract In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference, mostly caused by inhomogeneities and electronic disequilibrium, is highly correlated with the dose distribution and the underlying anatomical tissue density. We hypothesize that a conversion scheme can be established to boost low-accuracy doses to high-accuracy, using intensity information obtained from computed tomography (CT) images. A deep learning-driven framework was...
Source: Journal of Applied Clinical Medical Physics - June 19, 2020 Category: Physics Authors: Xing Y, Zhang Y, Nguyen D, Lin MH, Lu W, Jiang S Tags: J Appl Clin Med Phys Source Type: research

Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation.
CONCLUSIONS: The Monte Carlo results in general agree well with the measurement, which provides support in our commissioning procedure, as well as the full three-dimensional dose distribution of the patient phantom. PMID: 32559022 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 19, 2020 Category: Physics Authors: Li R, Tseng W, Wu Q Tags: J Appl Clin Med Phys Source Type: research

Characterization and verification of lead thickness of commercially available lead foil tape for the measurements of lead equivalency of radio-protective shields.
Abstract PURPOSE: Radiation protective apparatus is normally specified in "millimeter" of lead equivalence. Typically, it is less than 0.5 mmPb with the exception of lead eyeglasses, which may be 0.75 mmPb equivalent. Upon discovery of commercially available lead foil tape, manufactured by 3M™ "Lead Foil Tape 421" (LFT) which is designed for industrial utility applications. We set out to determine if this LFT can, indeed, be employed as the reference lead in the evaluation of lead equivalency of various protective apparatus. METHOD: The LFT is cut to appropriate size (50&nb...
Source: Journal of Applied Clinical Medical Physics - June 18, 2020 Category: Physics Authors: Lin PP, Aljabal AF, Wargo RR Tags: J Appl Clin Med Phys Source Type: research

Validating robotic couch isocentricity with 3D surface imaging.
This study assesses the specificity and sensitivity of a commercial 3D surface imaging system, AlignRT (Vision RT, London UK) for validating couch rotations. MATERIALS & METHODS: In clinical operation, a reference surface image of the patient is acquired after radiographic setup with couch at 270°, perpendicular to the gantry axis of rotation. The couch is then rotated ±90° to a typical treatment angle, and AlignRT reports a 3D displacement vector. Patient motion, changes in patient surface, non-coincidence between AlignRT and couch isocenter, and mechanical couch run-out all contribute to the 3D ve...
Source: Journal of Applied Clinical Medical Physics - June 15, 2020 Category: Physics Authors: El-Sherif O, Remmes NB, Kruse JJ Tags: J Appl Clin Med Phys Source Type: research

A dearth of specifications regarding primary diagnostic monitors (PDMs) for nuclear medicine leaves us with little guidance during the COVID-19 pandemic.
PMID: 32543024 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 15, 2020 Category: Physics Authors: Song N, Zuckier LS Tags: J Appl Clin Med Phys Source Type: research

Predictive quality assurance of a linear accelerator based on the machine performance check application using statistical process control and ARIMA forecast modeling.
CONCLUSION: Predictive quality assurance with the MPC will allow preventative maintenance, which could lead to improved linac performance and a reduction in unscheduled linac downtime. PMID: 32543097 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 15, 2020 Category: Physics Authors: Puyati W, Khawne A, Barnes M, Zwan B, Greer P, Fuangrod T Tags: J Appl Clin Med Phys Source Type: research

Investigation of tumor and vessel motion correlation in the liver.
Abstract Intrafraction imaging-based motion management systems for external beam radiotherapy can rely on internal surrogate structures when the target is not easily visualized. This work evaluated the validity of using liver vessels as internal surrogates for the estimation of liver tumor motion. Vessel and tumor motion were assessed using ten two-dimensional sagittal MR cine datasets collected on the ViewRay MRIdian. For each case, a liver tumor and at least one vessel were tracked for 175 s. A tracking approach utilizing block matching and multiple simultaneous templates was applied. Accuracy of the tracke...
Source: Journal of Applied Clinical Medical Physics - June 13, 2020 Category: Physics Authors: Jupitz SA, Shepard AJ, Hill PM, Bednarz BP Tags: J Appl Clin Med Phys Source Type: research

Feasibility study for marker-based VMAT plan optimization toward tumor tracking.
In conclusion, we demonstrate that visibility constraints can be incorporated into the optimization together with dosimetric objectives to produce treatment plans satisfying both objectives. This approach should ensure greater clinical success when applying real-time tracking algorithms, using VMAT delivery. PMID: 32525615 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 11, 2020 Category: Physics Authors: Omotayo AA, Venkataraman S, Venugopal N, McCurdy B Tags: J Appl Clin Med Phys Source Type: research

Facial expression monitoring system for predicting patient's sudden movement during radiotherapy using deep learning.
CONCLUSION: We developed a system that monitors the patient's facial expressions and predicts patient's advanced movement during the treatment. It was confirmed that our patient monitoring system can be complementarily used with the existing monitoring system. This system will help in maintaining the initial setup and improving the accuracy of radiotherapy for the patients using deep learning in radiotherapy. PMID: 32515552 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 9, 2020 Category: Physics Authors: Kim KH, Park K, Kim H, Jo B, Ahn SH, Kim C, Kim M, Kim TH, Lee SB, Shin D, Lim YK, Jeong JH Tags: J Appl Clin Med Phys Source Type: research

The helically-acquired CTDIvol as an alternative to traditional methodology.
CONCLUSION: There was excellent agreement between the two measurement methods and to the displayed CTDIvol , without protocol or vendor dependence. The helical CTDIvol measurement can be accomplished more easily than the axial method on many scanners and is reasonable to use for QC purposes. PMID: 32519415 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 9, 2020 Category: Physics Authors: Leon SM, Kobistek RJ, Olguin EA, Zhang Z, Barreto IL, Schwarz BC Tags: J Appl Clin Med Phys Source Type: research

A review of patient questions from physicist-patient consults.
CONCLUSION: Physicist-patient consults provided an opportunity to address the technical aspects of radiation therapy with patients in greater detail. The fact that patient questions could be conveniently grouped into only four topical categories indicates that it may be straightforward for other medical physicists to prepare for effectively addressing technical questions during physicist-patient consults. PMID: 32519450 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 9, 2020 Category: Physics Authors: Atwood TF, Brown DW, Juang T, Moore KL, McConnell KA, Steers JM, Murphy JD, Mundt AJ, Pawlicki T Tags: J Appl Clin Med Phys Source Type: research

Comparison on radiation effective dose and image quality of right coronary artery on prospective ECG-gated method between 320 row CT and 2nd generation (128-slice) dual source CT.
Abstract This retrospective study was to compare the image quality of right coronary artery (RCA) and effective radiation dose on prospective ECG-gated method between 320 row computed tomography (CT) and 2nd generation (128-slice) dual source CT. A total of 215 candidates underwent CT coronary angiography using prospective ECG-gated method, 120 patients enrolled in 320 row CT group, and 95 patients in dual source CT group. We divided RCA image quality scores as 1/2/3/4, which means excellent/good/adequate/not assessable and heart rates were considered, as well as the radiation dose. There is no statistically signi...
Source: Journal of Applied Clinical Medical Physics - June 8, 2020 Category: Physics Authors: Li RF, Hou CL, Zhou H, Dai YS, Jin LQ, Xi Q, Zhang JH Tags: J Appl Clin Med Phys Source Type: research

An open-source software for monitoring intrafraction motion during external beam radiation therapy based on superimposition of contours of projected ROIs on cine-MV images.
lot M Abstract PURPOSE: To present an open-source software (https://github.com/CHUSRadOncPhys/FluoMV) for monitoring intrafraction motion that is based on the visualization of superimposed contours of projected region-of-interests from DICOM RTSTRUCT files on cine-MV images acquired and displayed in real-time during radiation therapy delivery. Clinical use with prostate gold fiducial markers is presented. METHODS: Projections of regions of interest (ROI) in the reference frame of the electronic portal imaging device are computed offline for different gantry angles before the first treatment fraction. During t...
Source: Journal of Applied Clinical Medical Physics - June 7, 2020 Category: Physics Authors: Lessard R, Tremblay NM, Plourde MÉ, Guillot M Tags: J Appl Clin Med Phys Source Type: research

Development of a stereoscopic CT metal artifact management algorithm using gantry angle tilts for head and neck patients.
Abstract Dental amalgams are a common source of artifacts in head and neck (HN) images. Commercial artifact reduction techniques have been offered, but are substantially ineffectual at reducing artifacts from dental amalgams, can produce additional artifacts, provide inaccurate HU information, or require extensive computation time, and thus offer limited clinically utility. The goal of this work was to define and validate a novel algorithm and provide a phantom-based testing as proof of principle. An initial clinical comparison to a vendor's current solution was also performed. The algorithm uses two-angled CT sca...
Source: Journal of Applied Clinical Medical Physics - June 7, 2020 Category: Physics Authors: Branco D, Kry S, Taylor P, Rong J, Zhang X, Peterson C, Frank S, Followill D Tags: J Appl Clin Med Phys Source Type: research

Evaluating the positional uncertainty of intrafraction, adjacent fields, and daily setup with the BrainLAB ExacTrac system in patients who are receiving craniospinal irradiation.
CONCLUSIONS: Position correction is necessary after setup and the transposition of the treatment isocenter. Intra-fraction motion in the lateral direction should be monitored throughout treatment. The position errors in junction areas are almost within the tolerance after correction. The patients did not exhibit any side-effects by the overall treatment. PMID: 32491280 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 3, 2020 Category: Physics Authors: Duan X, Zhou Y, Dai H, Zhao L, Qian J, Yang D, Zhang L, Luo C, Li G Tags: J Appl Clin Med Phys Source Type: research

The COVID-19 Pandemic-Can open access modeling give us better answers more quickly?
PMID: 32476231 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 1, 2020 Category: Physics Authors: Beth Allen M, Mills M, Mirsaeidi M Tags: J Appl Clin Med Phys Source Type: research

The dosimetric impact of stabilizing spinal implants in radiotherapy treatment planning with protons and photons: standard titanium alloy vs. radiolucent carbon-fiber-reinforced PEEK systems.
CONCLUSIONS: While VMAT plans showed no relevant difference in dosimetric quality between both screw types, IMPT plans demonstrated the benefit of CFP screws through a smaller dosimetric impact of CT-value uncertainties compared to Ti. Reducing metal components in implants will therefore improve dose calculation accuracy and lower the risk for tumor underdosage. PMID: 32476247 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 31, 2020 Category: Physics Authors: Müller BS, Ryang YM, Oechsner M, Düsberg M, Meyer B, Combs SE, Wilkens JJ Tags: J Appl Clin Med Phys Source Type: research

Definition of internal target volumes based on planar X-ray fluoroscopic images for lung and hepatic stereotactic body radiation therapy. Comparison to inhale/exhale CT technique.
CONCLUSIONS: Use of FI with the linac built-in CBCT system is feasible for ITV definition. Large differences between motion amplitudes detected with FI and IECT methods were found. The method presented in this work based on FI could represent an improvement in ITV definition compared to the method based on IECT due to FI permits tumor motion acquisition in a more realistic situation than IECT. PMID: 32472618 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 30, 2020 Category: Physics Authors: Sevillano D, Núñez LM, Chevalier M, García-Vicente F Tags: J Appl Clin Med Phys Source Type: research

A robust VMAT delivery solution for single-fraction lung SABR utilizing FFF beams minimizing dosimetric compromise.
Abstract Peripheral lung lesions treated with a single fraction of stereotactic ablative body radiotherapy (SABR) utilizing volumetric modulated arc therapy (VMAT) delivery and flattening filter-free (FFF) beams represent a potentially high-risk scenario for clinically significant dose blurring effects due to interplay between the respiratory motion of the lesion and dynamic multi-leaf collimators (MLCs). The aim of this study was to determine an efficient means of developing low-modulation VMAT plans in the Eclipse treatment planning system (v15.5, Varian Medical Systems, Palo Alto, USA) in order to minimize this...
Source: Journal of Applied Clinical Medical Physics - May 29, 2020 Category: Physics Authors: Burton A, Offer K, Hardcastle N Tags: J Appl Clin Med Phys Source Type: research

A practical method for predicting patient-specific collision in radiotherapy.
CONCLUSION: This study provides a reliable, accurate, and fast collision prediction during the treatment planning process. Potential collisions can be discovered and prevented early before delivering. This method can integrate with the current clinical workflow without any additional required resources, and contribute to improvement in the safety and efficiency of the clinic. PMID: 32462733 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 28, 2020 Category: Physics Authors: Miao J, Niu C, Liu Z, Tian Y, Dai J Tags: J Appl Clin Med Phys Source Type: research

Three-dimensional printing in radiation oncology: A systematic review of the literature.
Abstract PURPOSE/OBJECTIVES: Three-dimensional (3D) printing is recognized as an effective clinical and educational tool in procedurally intensive specialties. However, it has a nascent role in radiation oncology. The goal of this investigation is to clarify the extent to which 3D printing applications are currently being used in radiation oncology through a systematic review of the literature. MATERIALS/METHODS: A search protocol was defined according to preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Included articles were evaluated using parameters of interest includ...
Source: Journal of Applied Clinical Medical Physics - May 27, 2020 Category: Physics Authors: Rooney MK, Rosenberg DM, Braunstein S, Cunha A, Damato AL, Ehler E, Pawlicki T, Robar J, Tatebe K, Golden DW Tags: J Appl Clin Med Phys Source Type: research

Automation of Monte Carlo-based treatment plan verification for proton therapy.
CONCLUSION: An automated framework for running MC calculations was developed which enables the calculation of dose and linear energy transfer within a clinically relevant workflow and timeline. The models and framework were validated against patient specific QA measurements and exhibited excellent agreement. Before this implementation, execution was prohibitively complex for an untrained individual and its use restricted to a research environment. PMID: 32452657 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 26, 2020 Category: Physics Authors: Kaluarachchi M, Moskvin V, Pirlepesov F, Wilson LJ, Xie F, Faught AM Tags: J Appl Clin Med Phys Source Type: research

Impact of varying air cavity on planning dosimetry for rectum patients treated on a 1.5  T hybrid MR-linac system.
CONCLUSIONS: Air cavities inside rectum affects rectum plan dosimetry due ERE. Location and magnitude of hot spots are dependent on the size of the air cavity. PMID: 32445292 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 23, 2020 Category: Physics Authors: Godoy Scripes P, Subashi E, Burleson S, Liang J, Romesser P, Crane C, Mechalakos J, Hunt M, Tyagi N Tags: J Appl Clin Med Phys Source Type: research

Evaluation of the PTW microDiamond in edge-on orientation for dosimetry in small fields.
CONCLUSIONS: The microDiamond was shown to be suitable for small field dosimetry when operated in edge-on orientation. When edge-on, a significantly reduced angular dependence is observed with no significant stem effect, making it a more versatile QA instrument for rotational delivery techniques. PMID: 32441884 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 22, 2020 Category: Physics Authors: Brace OJ, Alhujaili SF, Paino JR, Butler DJ, Wilkinson D, Oborn BM, Rosenfeld AB, Lerch MLF, Petasecca M, Davis JA Tags: J Appl Clin Med Phys Source Type: research

Limiting treatment plan complexity by applying a novel commercial tool.
CONCLUSIONS: This first experience suggests that the ASC is an effective tool to reduce the unnecessary complexity of a plan. This turns into an increased plan deliverability with no loss of plan quality. PMID: 32436656 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 21, 2020 Category: Physics Authors: Scaggion A, Fusella M, Agnello G, Bettinelli A, Pivato N, Roggio A, Rossato MA, Sepulcri M, Paiusco M Tags: J Appl Clin Med Phys Source Type: research

A comprehensive and clinical-oriented evaluation criteria based on DVH information and gamma passing rates analysis for IMRT plan 3D verification.
Abstract PURPOSE: To accomplish the 3D dose verification to IMRT plan by incorporating DVH information and gamma passing rates (GPs) (DVH_GPs) so as to better correlate the patient-specific quality assurance (QA) results with clinically relevant metrics. MATERIALS AND METHODS: DVH_GPs analysis was performed to specific structures of 51 intensity-modulated radiotherapy (IMRT) treatment plans (17 plans each for oropharyngeal neoplasm, esophageal neoplasm, and cervical neoplasm) with Delta4 3D dose verification system. Based on the DVH action levels of 5% and GPs action levels of 90% (3%/2 mm), the evaluati...
Source: Journal of Applied Clinical Medical Physics - May 20, 2020 Category: Physics Authors: Yi X, Lu WL, Dang J, Huang W, Cui HX, Wu WC, Li Y, Jiang QF Tags: J Appl Clin Med Phys Source Type: research

Mitigating disruptions, and scalability of radiation oncology physics work during the COVID-19 pandemic.
CONCLUSION: At the current level of disease in the United States, all three models have sustained major system stress in continuing reduced operation. However, the small clinic model may not perform if either the current level of infections is maintained for long or staff becomes unavailable due to health issues. With abundance, and diversity of innovative resources, medium and large clinic models can sustain further for physics-related radiotherapy services. PMID: 32432389 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 20, 2020 Category: Physics Authors: Darafsheh A, Lavvafi H, Taleei R, Khan R Tags: J Appl Clin Med Phys Source Type: research

Commissioning of a 1.5T Elekta Unity MR-linac: A single institution experience.
Abstract MR image-guided radiotherapy has the potential to improve patient care, but integration of an MRI scanner with a linear accelerator adds complexity to the commissioning process. This work describes a single institution experience of commissioning an Elekta Unity MR-linac, including mechanical testing, MRI scanner commissioning, and dosimetric validation. Mechanical testing included multileaf collimator (MLC) positional accuracy, measurement of radiation isocenter diameter, and MR-to-MV coincidence. Key MRI tests included magnetic field homogeneity, geometric accuracy, image quality, and the accuracy of na...
Source: Journal of Applied Clinical Medical Physics - May 20, 2020 Category: Physics Authors: Snyder JE, St-Aubin J, Yaddanapudi S, Boczkowski A, Dunkerley DAP, Graves SA, Hyer DE Tags: J Appl Clin Med Phys Source Type: research

Integration of automation into an existing clinical workflow to improve efficiency and reduce errors in the manual treatment planning process for total body irradiation (TBI).
Abstract PURPOSE: To identify causes of error, and present the concept of an automated technique that improves efficiency and helps to reduce transcription and manual data entry errors in the treatment planning of total body irradiation (TBI). METHODS: Analysis of incidents submitted to incident learning system (ILS) was performed to identify potential avenues for improvement by implementation of automation of the manual treatment planning process for total body irradiation (TBI). Following this analysis, it became obvious that while the individual components of the TBI treatment planning process were well im...
Source: Journal of Applied Clinical Medical Physics - May 19, 2020 Category: Physics Authors: Thomas DH, Miller B, Rabinovitch R, Milgrom S, Kavanagh B, Diot Q, Miften M, Schubert LK Tags: J Appl Clin Med Phys Source Type: research

Prediction of the output factor using machine and deep learning approach in uniform scanning proton therapy.
CONCLUSION: The GPR and SNN models outperformed the EM in terms of prediction accuracy. Machine and deep learning algorithms predicted the output factor and MU for USPT with higher predictive accuracy than EM. In our clinic, these models have been adopted as a secondary check of MU or output factors. PMID: 32419245 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 17, 2020 Category: Physics Authors: Grewal HS, Chacko MS, Ahmad S, Jin H Tags: J Appl Clin Med Phys Source Type: research

Investigating split-filter dual-energy CT for improving liver tumor visibility for radiation therapy.
CONCLUSIONS: Liver tumor contrast was significantly improved using split-filter DECT 40 keV VMIs compared to mixed images. On average, there was no statistical difference in CNR between the mixed images and VMIs, but for individual cases, CNR was greatly increased for the 57 keV and 40 keV VMIs. Therefore, although not universally successful for our patient cohort, split-filter DECT VMIs may provide substantial gains in tumor visibility of certain liver cases for radiation therapy treatment planning. PMID: 32410336 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 15, 2020 Category: Physics Authors: DiMaso LD, Miller JR, Lawless MJ, Bassetti MF, DeWerd LA, Huang J Tags: J Appl Clin Med Phys Source Type: research

Independent calculation-based verification of volumetric-modulated arc therapy-stereotactic body radiotherapy plans for lung cancer.
This study aimed to investigate the feasibility of independent calculation-based verification of volumetric-modulated arc therapy (VMAT)-stereotactic body radiotherapy (SBRT) for patients with lung cancer using a secondary treatment planning system (sTPS). In all, 50 patients with lung cancer who underwent VMAT-SBRT between April 2018 and May 2019 were included in this study. VMAT-SBRT plans were devised using the Collapsed-Cone Convolution in RayStation (primary TPS: pTPS). DICOM files were transferred to Eclipse software (sTPS), which utilized the Eclipse software, and the dose distribution was then recalculated using Ac...
Source: Journal of Applied Clinical Medical Physics - May 11, 2020 Category: Physics Authors: Ono T, Mitsuyoshi T, Shintani T, Tsuruta Y, Iramina H, Hirashima H, Miyabe Y, Nakamura M, Matsuo Y, Mizowaki T Tags: J Appl Clin Med Phys Source Type: research

Image artifacts caused by incorrect bowtie filters in cone-beam CT image-guided radiotherapy.
Abstract Certain models of cone beam computed tomography (CBCT) image-guided radiotherapy (IGRT) systems require manually placing the appropriate bowtie filter according to the relevant imaging protocol. Inadvertently using a wrong bowtie filter or no bowtie filter could cause unexpected image artifacts. In this work, CBCT image artifact patterns caused by different bowtie filter placement were evaluated. CBCT images of CT phantoms, that is, a Body Norm phantom, a Catphan® phantom and an anthropomorphic RANDO® phantom, were acquired at a Varian Trilogy® unit with an On-Board Imager® (OBI) system. T...
Source: Journal of Applied Clinical Medical Physics - May 8, 2020 Category: Physics Authors: Cao Y, Ma T, de Boer SF, Wang IZ Tags: J Appl Clin Med Phys Source Type: research

Technical Note: A step-by-step guide to Temporally Feathered Radiation Therapy planning for head and neck cancer.
CONCLUSIONS: Temporally Feathered Radiation Therapy planning is possible with modern treatment planning systems. Modest dosimetric changes are observed with TFRT planning compared with non-TFRT IMRT planning. We await the results of the current prospective trial to seeking to demonstrate the feasibility of TFRT in the modern clinical workflow (NCT03768856). Further studies will be required to demonstrate the potential benefit of TFRT over non-TFRT IMRT Planning. PMID: 32383296 [PubMed - as supplied by publisher] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 8, 2020 Category: Physics Authors: Parsai S, Qiu RLJ, Qi P, Alfonso JCL, Donaghue J, Murray E, Majkszak D, Dorio N, Fuller CD, Brock K, Koyfman S, Woody N, Joshi N, Scott JG Tags: J Appl Clin Med Phys Source Type: research