Radiobiological evaluation considering setup error on single-isocenter irradiation in stereotactic radiosurgery
CONCLUSION: The TCP in SRS for multiple brain metastases with a single-isocenter technique may decrease with increasing isocenter distance and decreasing GTV size when the 6DoF setup errors are exceeded (1.0 mm, 1.0°). Additionally, it might be possible to better maintain TCP for GTVs with 6DoF setup errors by using the optimal isocenter position.PMID:34151498 | DOI:10.1002/acm2.13322 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 21, 2021 Category: Physics Authors: Hisashi Nakano Satoshi Tanabe Ryuta Sasamoto Takeshi Takizawa Satoru Utsunomiya Madoka Sakai Toshimichi Nakano Atsushi Ohta Motoki Kaidu Hiroyuki Ishikawa Source Type: research

Evaluation of 4-Hz log files and secondary Monte Carlo dose calculation as patient-specific quality assurance for VMAT prostate plans
CONCLUSION: SciMoCa calculations of Monaco RT plans and RT log file plans are in excellent agreement to each other. Therefore, 4-Hz log files and SciMoCa can replace labor-intensive phantom-based measurements as patient-specific QA.PMID:34151502 | DOI:10.1002/acm2.13315 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 21, 2021 Category: Physics Authors: Philipp Szeverinski Matthias Kowatsch Thomas K ├╝nzler Marco Meinschad Patrick Clemens Alexander F DeVries Source Type: research

Reducing variability among treatment machines using knowledge-based planning for head and neck, pancreatic, and rectal cancer
CONCLUSIONS: Dosimetric indices of RapidPlan model-based plans appear to be comparable to the ones based on clinical plans regardless of energies, MLC types, and disease sites. The results suggest that the RapidPlan model can generate treatment plans independent of the type of treatment machine.PMID:34151503 | DOI:10.1002/acm2.13316 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 21, 2021 Category: Physics Authors: Hideaki Hirashima Mitsuhiro Nakamura Nobutaka Mukumoto Ryo Ashida Kota Fujii Kiyonao Nakamura Aya Nakajima Katsuyuki Sakanaka Michio Yoshimura Takashi Mizowaki Source Type: research

Commissioning of and preliminary experience with a new fully integrated computed tomography linac
CONCLUSION: The commissioning results and clinical QA results show that the uRT-linac 506c platform exhibits good and stable performance in mechanical and dosimetric accuracy. The integrated CT system provides an efficient workflow for image guidance with submillimeter localization precision, and will be a good starting point to proceed advanced adaptive radiotherapy.PMID:34151504 | DOI:10.1002/acm2.13313 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 21, 2021 Category: Physics Authors: Lei Yu Jun Zhao Zhen Zhang Jiazhou Wang Weigang Hu Source Type: research

Survey of patient-specific quality assurance practice for IMRT and VMAT
The objectives were to assess the current state of PSQA practice, identify areas for potential improvement, and facilitate the continued improvement in standardization, consistency, efficacy, and efficiency of PSQA regionally. The survey asked 40 questions related to PSQA practice for IMRT/VMAT delivery. The questions addressed PSQA policy and procedure, delivery log evaluation, instrumentation, measurement setup and methodology, data analysis and interpretation, documentation, process, failure modes, and feedback. The focus of this survey was on PSQA activities related to routine IMRT/VMAT treatments on conventional linac...
Source: Journal of Applied Clinical Medical Physics - June 19, 2021 Category: Physics Authors: Gordon H Chan Lee C L Chin Ady Abdellatif Jean-Pierre Bissonnette Lesley Buckley Daria Comsa Dal Granville Jenna King Patrick L Rapley Aaron Vandermeer Source Type: research

Survey of patient-specific quality assurance practice for IMRT and VMAT
The objectives were to assess the current state of PSQA practice, identify areas for potential improvement, and facilitate the continued improvement in standardization, consistency, efficacy, and efficiency of PSQA regionally. The survey asked 40 questions related to PSQA practice for IMRT/VMAT delivery. The questions addressed PSQA policy and procedure, delivery log evaluation, instrumentation, measurement setup and methodology, data analysis and interpretation, documentation, process, failure modes, and feedback. The focus of this survey was on PSQA activities related to routine IMRT/VMAT treatments on conventional linac...
Source: Journal of Applied Clinical Medical Physics - June 19, 2021 Category: Physics Authors: Gordon H Chan Lee C L Chin Ady Abdellatif Jean-Pierre Bissonnette Lesley Buckley Daria Comsa Dal Granville Jenna King Patrick L Rapley Aaron Vandermeer Source Type: research

Increase in the intensity of an optical signal with fluorescein during proton and carbon-ion irradiation
CONCLUSION: We confirmed the increase in intensity of the luminescence of water by adding fluorescein for particle ions. With a small amount of Cherenkov light contamination in the images, such as protons, the relative distributions of the luminescence images with fluorescein were similar to that of water and will be used for range or dose determination in a short time.PMID:34124832 | DOI:10.1002/acm2.13309 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 14, 2021 Category: Physics Authors: Seiichi Yamamoto Takuya Yabe Takashi Akagi Source Type: research

Increase in the intensity of an optical signal with fluorescein during proton and carbon-ion irradiation
CONCLUSION: We confirmed the increase in intensity of the luminescence of water by adding fluorescein for particle ions. With a small amount of Cherenkov light contamination in the images, such as protons, the relative distributions of the luminescence images with fluorescein were similar to that of water and will be used for range or dose determination in a short time.PMID:34124832 | DOI:10.1002/acm2.13309 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 14, 2021 Category: Physics Authors: Seiichi Yamamoto Takuya Yabe Takashi Akagi Source Type: research

Increase in the intensity of an optical signal with fluorescein during proton and carbon-ion irradiation
CONCLUSION: We confirmed the increase in intensity of the luminescence of water by adding fluorescein for particle ions. With a small amount of Cherenkov light contamination in the images, such as protons, the relative distributions of the luminescence images with fluorescein were similar to that of water and will be used for range or dose determination in a short time.PMID:34124832 | DOI:10.1002/acm2.13309 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 14, 2021 Category: Physics Authors: Seiichi Yamamoto Takuya Yabe Takashi Akagi Source Type: research

Increase in the intensity of an optical signal with fluorescein during proton and carbon-ion irradiation
CONCLUSION: We confirmed the increase in intensity of the luminescence of water by adding fluorescein for particle ions. With a small amount of Cherenkov light contamination in the images, such as protons, the relative distributions of the luminescence images with fluorescein were similar to that of water and will be used for range or dose determination in a short time.PMID:34124832 | DOI:10.1002/acm2.13309 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 14, 2021 Category: Physics Authors: Seiichi Yamamoto Takuya Yabe Takashi Akagi Source Type: research

Increase in the intensity of an optical signal with fluorescein during proton and carbon-ion irradiation
CONCLUSION: We confirmed the increase in intensity of the luminescence of water by adding fluorescein for particle ions. With a small amount of Cherenkov light contamination in the images, such as protons, the relative distributions of the luminescence images with fluorescein were similar to that of water and will be used for range or dose determination in a short time.PMID:34124832 | DOI:10.1002/acm2.13309 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 14, 2021 Category: Physics Authors: Seiichi Yamamoto Takuya Yabe Takashi Akagi Source Type: research

Automated algorithm for calculation of setup corrections and planning target volume margins for offline image-guided radiotherapy protocols
CONCLUSIONS: In conclusion, the algorithm provides an automated method for optimization and reduction of PTV margin using logged setup errors from CBCT-based IGRT.PMID:34109736 | DOI:10.1002/acm2.13291 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Auwal Abubakar Nada Alia M Zamri Shazril Imran Shaukat Hafiz Mohd Zin Source Type: research

Automated procedure for slice thickness verification of computed tomography images: Variations of slice thickness, position from iso-center, and reconstruction filter
CONCLUSIONS: We successfully developed an automated procedure of slice thickness verification and confirmed that the automated procedure provided accurate results. It provided an easy and effective method of determining slice thickness.PMID:34109738 | DOI:10.1002/acm2.13317 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Nani Lasiyah Choirul Anam Eko Hidayanto Geoff Dougherty Source Type: research

Automated algorithm for calculation of setup corrections and planning target volume margins for offline image-guided radiotherapy protocols
CONCLUSIONS: In conclusion, the algorithm provides an automated method for optimization and reduction of PTV margin using logged setup errors from CBCT-based IGRT.PMID:34109736 | DOI:10.1002/acm2.13291 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Auwal Abubakar Nada Alia M Zamri Shazril Imran Shaukat Hafiz Mohd Zin Source Type: research

Automated procedure for slice thickness verification of computed tomography images: Variations of slice thickness, position from iso-center, and reconstruction filter
CONCLUSIONS: We successfully developed an automated procedure of slice thickness verification and confirmed that the automated procedure provided accurate results. It provided an easy and effective method of determining slice thickness.PMID:34109738 | DOI:10.1002/acm2.13317 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Nani Lasiyah Choirul Anam Eko Hidayanto Geoff Dougherty Source Type: research

Automated algorithm for calculation of setup corrections and planning target volume margins for offline image-guided radiotherapy protocols
CONCLUSIONS: In conclusion, the algorithm provides an automated method for optimization and reduction of PTV margin using logged setup errors from CBCT-based IGRT.PMID:34109736 | DOI:10.1002/acm2.13291 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Auwal Abubakar Nada Alia M Zamri Shazril Imran Shaukat Hafiz Mohd Zin Source Type: research

Automated procedure for slice thickness verification of computed tomography images: Variations of slice thickness, position from iso-center, and reconstruction filter
CONCLUSIONS: We successfully developed an automated procedure of slice thickness verification and confirmed that the automated procedure provided accurate results. It provided an easy and effective method of determining slice thickness.PMID:34109738 | DOI:10.1002/acm2.13317 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 10, 2021 Category: Physics Authors: Nani Lasiyah Choirul Anam Eko Hidayanto Geoff Dougherty Source Type: research

Impact of errors in spot size and spot position in robustly optimized pencil beam scanning proton-based stereotactic body radiation therapy (SBRT) lung plans
CONCLUSION: The increasing spot sizes resulted in decreased target coverage and dose homogeneity. Similarly, the decreasing spot sizes led to a loss of target coverage, overdosage, and degradation of dose homogeneity. The addition of spot size and position errors to plan robustness parameters (setup and range uncertainties) increased the target coverage loss and decreased the dose homogeneity.PMID:34101334 | DOI:10.1002/acm2.13293 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Suresh Rana Anatoly B Rosenfeld Source Type: research

Automated data abstraction for quality surveillance and outcome assessment in radiation oncology
We present the design and implementation framework of an integrated data abstraction, aggregation, and storage, curation, and analytics software: the Health Information Gateway and Exchange (HINGE), which collates data for cancer patients receiving radiotherapy. The HINGE software abstracts structured DICOM-RT data from the treatment planning system (TPS), treatment data from the treatment management system (TMS), and clinical data from the electronic health records (EHRs). HINGE software has disease site-specific "Smart" templates that facilitate the entry of relevant clinical information by physicians and clini...
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Rishabh Kapoor William C Sleeman Joseph J Nalluri Paul Turner Priyankar Bose Andrii Cherevko Sriram Srinivasan Khajamoinuddin Syed Preetam Ghosh Michael Hagan Jatinder R Palta Source Type: research

Impact of errors in spot size and spot position in robustly optimized pencil beam scanning proton-based stereotactic body radiation therapy (SBRT) lung plans
CONCLUSION: The increasing spot sizes resulted in decreased target coverage and dose homogeneity. Similarly, the decreasing spot sizes led to a loss of target coverage, overdosage, and degradation of dose homogeneity. The addition of spot size and position errors to plan robustness parameters (setup and range uncertainties) increased the target coverage loss and decreased the dose homogeneity.PMID:34101334 | DOI:10.1002/acm2.13293 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Suresh Rana Anatoly B Rosenfeld Source Type: research

Automated data abstraction for quality surveillance and outcome assessment in radiation oncology
We present the design and implementation framework of an integrated data abstraction, aggregation, and storage, curation, and analytics software: the Health Information Gateway and Exchange (HINGE), which collates data for cancer patients receiving radiotherapy. The HINGE software abstracts structured DICOM-RT data from the treatment planning system (TPS), treatment data from the treatment management system (TMS), and clinical data from the electronic health records (EHRs). HINGE software has disease site-specific "Smart" templates that facilitate the entry of relevant clinical information by physicians and clini...
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Rishabh Kapoor William C Sleeman Joseph J Nalluri Paul Turner Priyankar Bose Andrii Cherevko Sriram Srinivasan Khajamoinuddin Syed Preetam Ghosh Michael Hagan Jatinder R Palta Source Type: research

Impact of errors in spot size and spot position in robustly optimized pencil beam scanning proton-based stereotactic body radiation therapy (SBRT) lung plans
CONCLUSION: The increasing spot sizes resulted in decreased target coverage and dose homogeneity. Similarly, the decreasing spot sizes led to a loss of target coverage, overdosage, and degradation of dose homogeneity. The addition of spot size and position errors to plan robustness parameters (setup and range uncertainties) increased the target coverage loss and decreased the dose homogeneity.PMID:34101334 | DOI:10.1002/acm2.13293 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Suresh Rana Anatoly B Rosenfeld Source Type: research

Automated data abstraction for quality surveillance and outcome assessment in radiation oncology
We present the design and implementation framework of an integrated data abstraction, aggregation, and storage, curation, and analytics software: the Health Information Gateway and Exchange (HINGE), which collates data for cancer patients receiving radiotherapy. The HINGE software abstracts structured DICOM-RT data from the treatment planning system (TPS), treatment data from the treatment management system (TMS), and clinical data from the electronic health records (EHRs). HINGE software has disease site-specific "Smart" templates that facilitate the entry of relevant clinical information by physicians and clini...
Source: Journal of Applied Clinical Medical Physics - June 8, 2021 Category: Physics Authors: Rishabh Kapoor William C Sleeman Joseph J Nalluri Paul Turner Priyankar Bose Andrii Cherevko Sriram Srinivasan Khajamoinuddin Syed Preetam Ghosh Michael Hagan Jatinder R Palta Source Type: research

Examining electrometer performance checks with direct-current generator in a clinic: Assessment of generated charges and implementation of electrometer checks
J Appl Clin Med Phys. 2021 Jun 3. doi: 10.1002/acm2.13312. Online ahead of print.ABSTRACTPURPOSE: Medical physicists use a suitable detector connected to an electrometer to measure radiotherapy beams. Each detector and electrometer has a lifetime (due to physical deterioration of detector components and electrical characteristic deterioration in electronic electrometer components), long-term stability [according to IEC 60731:2011, ≤0.5% (reference-class dosimeter)], and calibration frequency [according to Muir et al. (J Appl Clin Med Phys. 2017; 18:182-190), generally 2 years]; thus, physicists should check the electrom...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Naoki Kinoshita Hiroshi Oguchi Morihito Shimizu Eiji Kidoya Hiroki Shioura Hirohiko Kimura Source Type: research

On the evaluation of mobile target trajectory between four-dimensional computer tomography and four-dimensional cone-beam computer tomography
This study evaluates the discrepancies between the reconstructed motion of 4D CBCT and 4D CT imaging over a wide range of sine target motion parameters and patient waveforms.METHODS: A thorax motion phantom was used to examine 24 sine motions with varying amplitudes and cycle times and seven patient waveforms. Each programmed motion was imaged using 4D CT and 4D CBCT. The images were processed to auto segment the target. For sine motion, the target centroid at each phase was fitted to a sinusoidal curve to evaluate equivalence in amplitude between the two imaging modalities. The patient waveform motion was evaluated based ...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Colton Baley Neil Kirby Timothy Wagner Nikos Papanikolaou Pamela Myers Karl Rasmussen Sotirios Stathakis Daniel Saenz Source Type: research

Examining electrometer performance checks with direct-current generator in a clinic: Assessment of generated charges and implementation of electrometer checks
J Appl Clin Med Phys. 2021 Jun 3. doi: 10.1002/acm2.13312. Online ahead of print.ABSTRACTPURPOSE: Medical physicists use a suitable detector connected to an electrometer to measure radiotherapy beams. Each detector and electrometer has a lifetime (due to physical deterioration of detector components and electrical characteristic deterioration in electronic electrometer components), long-term stability [according to IEC 60731:2011, ≤0.5% (reference-class dosimeter)], and calibration frequency [according to Muir et al. (J Appl Clin Med Phys. 2017; 18:182-190), generally 2 years]; thus, physicists should check the electrom...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Naoki Kinoshita Hiroshi Oguchi Morihito Shimizu Eiji Kidoya Hiroki Shioura Hirohiko Kimura Source Type: research

On the evaluation of mobile target trajectory between four-dimensional computer tomography and four-dimensional cone-beam computer tomography
This study evaluates the discrepancies between the reconstructed motion of 4D CBCT and 4D CT imaging over a wide range of sine target motion parameters and patient waveforms.METHODS: A thorax motion phantom was used to examine 24 sine motions with varying amplitudes and cycle times and seven patient waveforms. Each programmed motion was imaged using 4D CT and 4D CBCT. The images were processed to auto segment the target. For sine motion, the target centroid at each phase was fitted to a sinusoidal curve to evaluate equivalence in amplitude between the two imaging modalities. The patient waveform motion was evaluated based ...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Colton Baley Neil Kirby Timothy Wagner Nikos Papanikolaou Pamela Myers Karl Rasmussen Sotirios Stathakis Daniel Saenz Source Type: research

Examining electrometer performance checks with direct-current generator in a clinic: Assessment of generated charges and implementation of electrometer checks
J Appl Clin Med Phys. 2021 Jun 3. doi: 10.1002/acm2.13312. Online ahead of print.ABSTRACTPURPOSE: Medical physicists use a suitable detector connected to an electrometer to measure radiotherapy beams. Each detector and electrometer has a lifetime (due to physical deterioration of detector components and electrical characteristic deterioration in electronic electrometer components), long-term stability [according to IEC 60731:2011, ≤0.5% (reference-class dosimeter)], and calibration frequency [according to Muir et al. (J Appl Clin Med Phys. 2017; 18:182-190), generally 2 years]; thus, physicists should check the electrom...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Naoki Kinoshita Hiroshi Oguchi Morihito Shimizu Eiji Kidoya Hiroki Shioura Hirohiko Kimura Source Type: research

On the evaluation of mobile target trajectory between four-dimensional computer tomography and four-dimensional cone-beam computer tomography
This study evaluates the discrepancies between the reconstructed motion of 4D CBCT and 4D CT imaging over a wide range of sine target motion parameters and patient waveforms.METHODS: A thorax motion phantom was used to examine 24 sine motions with varying amplitudes and cycle times and seven patient waveforms. Each programmed motion was imaged using 4D CT and 4D CBCT. The images were processed to auto segment the target. For sine motion, the target centroid at each phase was fitted to a sinusoidal curve to evaluate equivalence in amplitude between the two imaging modalities. The patient waveform motion was evaluated based ...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Colton Baley Neil Kirby Timothy Wagner Nikos Papanikolaou Pamela Myers Karl Rasmussen Sotirios Stathakis Daniel Saenz Source Type: research

Examining electrometer performance checks with direct-current generator in a clinic: Assessment of generated charges and implementation of electrometer checks
J Appl Clin Med Phys. 2021 Jun 3. doi: 10.1002/acm2.13312. Online ahead of print.ABSTRACTPURPOSE: Medical physicists use a suitable detector connected to an electrometer to measure radiotherapy beams. Each detector and electrometer has a lifetime (due to physical deterioration of detector components and electrical characteristic deterioration in electronic electrometer components), long-term stability [according to IEC 60731:2011, ≤0.5% (reference-class dosimeter)], and calibration frequency [according to Muir et al. (J Appl Clin Med Phys. 2017; 18:182-190), generally 2 years]; thus, physicists should check the electrom...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Naoki Kinoshita Hiroshi Oguchi Morihito Shimizu Eiji Kidoya Hiroki Shioura Hirohiko Kimura Source Type: research

On the evaluation of mobile target trajectory between four-dimensional computer tomography and four-dimensional cone-beam computer tomography
This study evaluates the discrepancies between the reconstructed motion of 4D CBCT and 4D CT imaging over a wide range of sine target motion parameters and patient waveforms.METHODS: A thorax motion phantom was used to examine 24 sine motions with varying amplitudes and cycle times and seven patient waveforms. Each programmed motion was imaged using 4D CT and 4D CBCT. The images were processed to auto segment the target. For sine motion, the target centroid at each phase was fitted to a sinusoidal curve to evaluate equivalence in amplitude between the two imaging modalities. The patient waveform motion was evaluated based ...
Source: Journal of Applied Clinical Medical Physics - June 4, 2021 Category: Physics Authors: Colton Baley Neil Kirby Timothy Wagner Nikos Papanikolaou Pamela Myers Karl Rasmussen Sotirios Stathakis Daniel Saenz Source Type: research

Fundamental study on quality assurance (QA) procedures for a real-time tumor tracking radiotherapy (RTRT) system from the viewpoint of imaging devices
CONCLUSION: The indicators of NEQ, MTF, and NPS were useful for managing the tracking accuracy of the RTRT system. We propose observing the change of these indicators as additional QA procedures for each imaging device from the commissioning baseline.PMID:34080303 | DOI:10.1002/acm2.13307 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - June 3, 2021 Category: Physics Authors: Suguru Kimura Naoki Miyamoto Kenneth L Sutherland Ryusuke Suzuki Hiroki Shirato Masayori Ishikawa Source Type: research

Investigation of absolute dose calibration accuracy for TomoTherapy using real water
J Appl Clin Med Phys. 2021 May 31. doi: 10.1002/acm2.13311. Online ahead of print.ABSTRACTA systematic bias in TomoTherapy output calibration was reported by the Imaging and Radiation Oncology Core Houston (IROC-H) after analyzing intensity-modulated radiation therapy (IMRT) credentialing results from hundreds of TomoTherapy units. Multiple theories were developed to explain this observation. One theory was that the use of a solid water "cheese" phantom instead of real water in the calibration measurement was the culprit. A phantom filled with distilled water was built to investigate whether our TomoTherapy was m...
Source: Journal of Applied Clinical Medical Physics - June 1, 2021 Category: Physics Authors: Tingtian Pang Bo Yang Xia Liu James R Castle Lang Yu Nan Liu Wenbo Li Tingting Dong Jie Qiu Quan Chen Source Type: research

Investigation of absolute dose calibration accuracy for TomoTherapy using real water
J Appl Clin Med Phys. 2021 May 31. doi: 10.1002/acm2.13311. Online ahead of print.ABSTRACTA systematic bias in TomoTherapy output calibration was reported by the Imaging and Radiation Oncology Core Houston (IROC-H) after analyzing intensity-modulated radiation therapy (IMRT) credentialing results from hundreds of TomoTherapy units. Multiple theories were developed to explain this observation. One theory was that the use of a solid water "cheese" phantom instead of real water in the calibration measurement was the culprit. A phantom filled with distilled water was built to investigate whether our TomoTherapy was m...
Source: Journal of Applied Clinical Medical Physics - June 1, 2021 Category: Physics Authors: Tingtian Pang Bo Yang Xia Liu James R Castle Lang Yu Nan Liu Wenbo Li Tingting Dong Jie Qiu Quan Chen Source Type: research

On the MLC leaves alignment in the direction orthogonal to movement
J Appl Clin Med Phys. 2021 May 30. doi: 10.1002/acm2.13267. Online ahead of print.ABSTRACTThe main focus of the recommended spatial accuracy tests for the multi-leaf collimators (MLC) is calibration of the leaf position along the movement direction and overall alignment to the radiation isocenter. No explicit attention was typically paid to the alignment of the leaves from the opposing banks in the direction orthogonal to movement. This paper is a case study demonstrating that verification of such alignment at the time of acceptance testing is prudent. The original standard MLC (SMLC) on an MRIdian MRI-guided linac (ViewRa...
Source: Journal of Applied Clinical Medical Physics - May 31, 2021 Category: Physics Authors: Kujtim Latifi Rajiv Lotey Vladimir Feygelman Source Type: research

A novel method to determine linac mechanical isocenter position and size and examples of specific QA applications
J Appl Clin Med Phys. 2021 May 30. doi: 10.1002/acm2.13257. Online ahead of print.ABSTRACTThe most important geometric characteristic of stereotactic treatment is the accuracy of positioning the target at the treatment isocenter and the accuracy of directing the radiation beam at the treatment isocenter. Commonly, the radiation isocenter is used as the reference for the treatment isocenter, but its method of localization is not strictly defined, and it depends on the linac-specific beam steering parameters. A novel method is presented for determining the linac mechanical isocenter position and size based on the localizatio...
Source: Journal of Applied Clinical Medical Physics - May 31, 2021 Category: Physics Authors: Jacek M Chojnowski Jonathan R Sykes David I Thwaites Source Type: research

On the MLC leaves alignment in the direction orthogonal to movement
J Appl Clin Med Phys. 2021 May 30. doi: 10.1002/acm2.13267. Online ahead of print.ABSTRACTThe main focus of the recommended spatial accuracy tests for the multi-leaf collimators (MLC) is calibration of the leaf position along the movement direction and overall alignment to the radiation isocenter. No explicit attention was typically paid to the alignment of the leaves from the opposing banks in the direction orthogonal to movement. This paper is a case study demonstrating that verification of such alignment at the time of acceptance testing is prudent. The original standard MLC (SMLC) on an MRIdian MRI-guided linac (ViewRa...
Source: Journal of Applied Clinical Medical Physics - May 31, 2021 Category: Physics Authors: Kujtim Latifi Rajiv Lotey Vladimir Feygelman Source Type: research

A novel method to determine linac mechanical isocenter position and size and examples of specific QA applications
J Appl Clin Med Phys. 2021 May 30. doi: 10.1002/acm2.13257. Online ahead of print.ABSTRACTThe most important geometric characteristic of stereotactic treatment is the accuracy of positioning the target at the treatment isocenter and the accuracy of directing the radiation beam at the treatment isocenter. Commonly, the radiation isocenter is used as the reference for the treatment isocenter, but its method of localization is not strictly defined, and it depends on the linac-specific beam steering parameters. A novel method is presented for determining the linac mechanical isocenter position and size based on the localizatio...
Source: Journal of Applied Clinical Medical Physics - May 31, 2021 Category: Physics Authors: Jacek M Chojnowski Jonathan R Sykes David I Thwaites Source Type: research

Interfractional robustness of scanning carbon ion radiotherapy for prostate cancer: An analysis based on dose distribution from daily in-room CT images
J Appl Clin Med Phys. 2021 May 27. doi: 10.1002/acm2.13275. Online ahead of print.ABSTRACTPURPOSE: We analyzed interfractional robustness of scanning carbon ion radiotherapy (CIRT) for prostate cancer based on the dose distribution using daily in-room computed tomography (CT) images.MATERIALS AND METHODS: We analyzed 11 consecutive patients treated with scanning CIRT for localized prostate cancer in our hospital between December 2015 and January 2016. In-room CT images were taken under treatment conditions in every treatment session. The dose distribution on each in-room CT image was recalculated, while retaining the penci...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Keisuke Tsuchida Shinichi Minohara Yohsuke Kusano Kio Kano Wataru Anno Yosuke Takakusagi Nobutaka Mizoguchi Itsuko Serizawa Daisaku Yoshida Koh Imura Yoshiki Takayama Tadashi Kamada Hiroyuki Katoh Tatsuya Ohno Source Type: research

Evaluation of the relationship between phantom position and computed tomography dose index in cone beam computed tomography when assuming breast irradiation
This study aims to investigate the influence of the phantom position on weighted computed tomography dose index (CTDIw ) in cone beam computed tomography (CBCT) when assuming breast irradiation. Computed tomography dose index (CTDI) was measured by the x-ray volume imaging of CBCT using parameters for image-guided radiation therapy (IGRT) in right breast irradiation. The measurement points of CTDI ranged from 0 (center) to 16 cm in the right-left (RL) direction, and from 0 (center) to 7.5 cm in the anterior-posterior (AP) direction, which assumed right breast irradiation. A nonuniform change exists in the relative value of...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Hiroyuki Ueno Kosuke Matsubara Akihiro Takemura Masato Hizume Sayuri Bou Source Type: research

Interfractional robustness of scanning carbon ion radiotherapy for prostate cancer: An analysis based on dose distribution from daily in-room CT images
J Appl Clin Med Phys. 2021 May 27. doi: 10.1002/acm2.13275. Online ahead of print.ABSTRACTPURPOSE: We analyzed interfractional robustness of scanning carbon ion radiotherapy (CIRT) for prostate cancer based on the dose distribution using daily in-room computed tomography (CT) images.MATERIALS AND METHODS: We analyzed 11 consecutive patients treated with scanning CIRT for localized prostate cancer in our hospital between December 2015 and January 2016. In-room CT images were taken under treatment conditions in every treatment session. The dose distribution on each in-room CT image was recalculated, while retaining the penci...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Keisuke Tsuchida Shinichi Minohara Yohsuke Kusano Kio Kano Wataru Anno Yosuke Takakusagi Nobutaka Mizoguchi Itsuko Serizawa Daisaku Yoshida Koh Imura Yoshiki Takayama Tadashi Kamada Hiroyuki Katoh Tatsuya Ohno Source Type: research

Evaluation of the relationship between phantom position and computed tomography dose index in cone beam computed tomography when assuming breast irradiation
This study aims to investigate the influence of the phantom position on weighted computed tomography dose index (CTDIw ) in cone beam computed tomography (CBCT) when assuming breast irradiation. Computed tomography dose index (CTDI) was measured by the x-ray volume imaging of CBCT using parameters for image-guided radiation therapy (IGRT) in right breast irradiation. The measurement points of CTDI ranged from 0 (center) to 16 cm in the right-left (RL) direction, and from 0 (center) to 7.5 cm in the anterior-posterior (AP) direction, which assumed right breast irradiation. A nonuniform change exists in the relative value of...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Hiroyuki Ueno Kosuke Matsubara Akihiro Takemura Masato Hizume Sayuri Bou Source Type: research

Interfractional robustness of scanning carbon ion radiotherapy for prostate cancer: An analysis based on dose distribution from daily in-room CT images
J Appl Clin Med Phys. 2021 May 27. doi: 10.1002/acm2.13275. Online ahead of print.ABSTRACTPURPOSE: We analyzed interfractional robustness of scanning carbon ion radiotherapy (CIRT) for prostate cancer based on the dose distribution using daily in-room computed tomography (CT) images.MATERIALS AND METHODS: We analyzed 11 consecutive patients treated with scanning CIRT for localized prostate cancer in our hospital between December 2015 and January 2016. In-room CT images were taken under treatment conditions in every treatment session. The dose distribution on each in-room CT image was recalculated, while retaining the penci...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Keisuke Tsuchida Shinichi Minohara Yohsuke Kusano Kio Kano Wataru Anno Yosuke Takakusagi Nobutaka Mizoguchi Itsuko Serizawa Daisaku Yoshida Koh Imura Yoshiki Takayama Tadashi Kamada Hiroyuki Katoh Tatsuya Ohno Source Type: research

Evaluation of the relationship between phantom position and computed tomography dose index in cone beam computed tomography when assuming breast irradiation
This study aims to investigate the influence of the phantom position on weighted computed tomography dose index (CTDIw ) in cone beam computed tomography (CBCT) when assuming breast irradiation. Computed tomography dose index (CTDI) was measured by the x-ray volume imaging of CBCT using parameters for image-guided radiation therapy (IGRT) in right breast irradiation. The measurement points of CTDI ranged from 0 (center) to 16 cm in the right-left (RL) direction, and from 0 (center) to 7.5 cm in the anterior-posterior (AP) direction, which assumed right breast irradiation. A nonuniform change exists in the relative value of...
Source: Journal of Applied Clinical Medical Physics - May 28, 2021 Category: Physics Authors: Hiroyuki Ueno Kosuke Matsubara Akihiro Takemura Masato Hizume Sayuri Bou Source Type: research

Four-dimensional dose calculations for dynamic tumour tracking with a gimbal-mounted linear accelerator
CONCLUSION: Dynamic tumor tracking plans optimized for a single respiratory phase leave an OAR vulnerable to exceeding its dose constraint during other respiratory phases. The rotation method accurately models the beam's geometry. Using deformable image registration to accumulate dose from all 10 breathing phases provides the most accurate results, however it is a time consuming procedure. Accumulating the dose from two extreme breathing phases (exhale and inhale) and weighting them properly provides accurate results while requiring less time. This approach should be used to confirm the safety of a DTT treatment plan prior...
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: Emilie E Carpentier Ronan L McDermott Emma M Dunne Marie-Laure A Camborde Alanah M Bergman Tania Karan Mitchell C C Liu Roy M K Ma Ante Mestrovic Source Type: research

CT-less electron radiotherapy simulation and planning with a consumer 3D camera
CONCLUSIONS: Electron beam dosimetry is affected by irregular body surfaces. 3D cameras can capture irregular body contours which allow accurate dosimetry of electron beam treatment as an alternative to costly CT scans with no extra exposure to radiation. Tools and workflow for clinical implementation are provided.PMID:34042253 | DOI:10.1002/acm2.13283 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: Lawrie Skinner Rick Knopp Yi-Chun Wang Piotr Dubrowski Karl K Bush Alyssa Limmer Nicholas Trakul Lynn Million Carol M Marquez Amy S Yu Source Type: research

Optimizing the effective spot size and the dosimetric leaf gap of the AcurosXB algorithm for VMAT treatment planning
CONCLUSION: The methodology provided is simple to implement in clinical practice. It was validated for three beam models covering a large variety of treatment types and localizations.PMID:34042259 | DOI:10.1002/acm2.13256 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: V Passal M Barreau T Tiplica S Dufreneix Source Type: research

Evaluation of a commercial synthetic computed tomography generation solution for magnetic resonance imaging-only radiotherapy
CONCLUSION: The performances of the software were shown to be similar to other sCT generation algorithms in terms of HU difference, dose comparison and daily image localization.PMID:34042268 | DOI:10.1002/acm2.13236 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: A Gonzalez-Moya S Dufreneix N Ouyessad C Guillerminet D Autret Source Type: research

Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
CONCLUSION: The FDN -based energy metric D10cm (FDN ) can be used for acceptance testing of beam energy, and also for the verification of energy in periodic quality assurance (QA) processes.PMID:34042271 | DOI:10.1002/acm2.13281 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: Song Gao Mikhail A Chetvertkov Bin Cai Abhishek Dwivedi Dimitris Mihailidis Xenia Ray Tucker Netherton Laurence E Court William E Simon Peter A Balter Source Type: research

In regards to Pokhrel et al. Clinical validation of ring-mounted halcyon linac for lung SBRT: Comparison to SBRT-dedicated C-arm linac treatments. JACMP 2021 Jan;22(1):261-70
J Appl Clin Med Phys. 2021 May 27. doi: 10.1002/acm2.13273. Online ahead of print.NO ABSTRACTPMID:34042272 | DOI:10.1002/acm2.13273 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - May 27, 2021 Category: Physics Authors: Biplab Sarkar Tanmay Ghosh Subhra Singhdha Biswal Tanweer Shahid Tharmarnadar Ganesh Source Type: research