Filtered By:
Infectious Disease: Aspergillus
This page shows you your search results in order of date. This is page number 19.
Order by Relevance | Date
Total 481 results found since Jan 2013.
Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial
This study aimed to examine the traditional use of Ginkgo seeds as topical treatment for skin disorders for potential antibacterial efficacy. This is the first study to test and compare the antibacterial activity of various Ginkgo seed extracts on skin pathogens.
In this work, we confirmed the ethnomedicinal importance of seeds in the treatment of skin diseases. As reported in the Compendium of Materia Medica Ben Cao Gang Mu, only the seeds were used for medicinal uses, especially as a topical treatment for skin infections. Moreover, our study validates the antimicrobial activity of the seed (i.e., seed coats and immature...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research
Dietary Vitamin D3 Deficiency Increases Resistance to Leishmania (Leishmania) amazonensis Infection in Mice
Conclusion
Altogether, our results indicate that dietary VitD deficiency is able to decrease lesion growth and provide an increase in Th1 response in C57BL/6 and BALB/c mice upon L. (L.) amazonensis infection, although it does not decrease parasite burden in either of the murine models used. Thus, VitD may contribute to host susceptibility to murine tegumentary leishmaniasis. Further studies on the influence of immunonutrition in the leishmaniases are needed to better understand the immunobiology of these diseases.
Author Contributions
HdMG conceived and designed the experiments. GO-S, DB, MM, JEP, JCP, TR, AdF-M, and L...
Source: Frontiers in cellular and infection microbiology - April 9, 2019 Category: Microbiology Source Type: research
BET Bromodomain Inhibitor iBET151 Impedes Human ILC2 Activation and Prevents Experimental Allergic Lung Inflammation
This study was supported by grants from GSK and the UK Medical Research Council (U105178805).
Conflict of Interest Statement
AM has grant funding from GSK and AstraZeneca/MedImmune. MB, DJ, AP, DT, and AvO are employees of GSK.
The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Acknowledgments
We are grateful to the Ares staff, genotyping facility, and flow cytometry core for their technical assistance. We thank Jen Walker for advice on the manuscript.
Supplementary Material
The Supplem...
Source: Frontiers in Immunology - April 8, 2019 Category: Allergy & Immunology Source Type: research
Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis
ConclusionAlthough fungal antigens are known to potentiate immune response through innate cytokines, including IL ‐25, the early expansion of SCCs in the presence of fungus has not been described. This early event in the pathogenesis of noninvasive fungal rhinosinusitis may represent a target for intervention.
Source: International Forum of Allergy and Rhinology - March 19, 2019 Category: Allergy & Immunology Authors: Neil N. Patel,
Vasiliki Triantafillou,
Ivy W. Maina,
Alan D. Workman,
Charles C. L. Tong,
Edward C. Kuan,
Peter Papagiannopoulos,
John V. Bosso,
Nithin D. Adappa,
James N. Palmer,
Michael A. Kohanski,
De'Broski R. Herbert,
Noam A. Cohen Tags: ORIGINAL ARTICLE Source Type: research
Spectrum of pulmonary aspergillosis in Hyper IgE syndrome with autosomal dominant STAT3 deficiency
ConclusionChronic and allergic forms of aspergillosis occurred in 17.5% of STAT3 deficient patients, mostly in lung cavities. Almost half had recurrences, despite prolonged antifungal treatment and/or surgery.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 14, 2019 Category: Allergy & Immunology Source Type: research
Allergic Bronchopulmonary Mycosis due to fungi other than Aspergillus.
Authors: Deepak L, Singh Rajput M, Sharma B
Abstract
Summary: Allergic bronchopulmonary mycosis (ABPM) is a clinical syndrome associated with immune sensitivity to various fungi that colonize the airways. Early diagnosis and treatment with systemic corticosteroids is the key in preventing the progression of the disease to irreversible lung fibrosis. Although Aspergillus has progressively gained recognition as a causative agent in past few decades, other fungi, that have been reported to cause ABPM, are not yet widely evaluated. We studied hundred and two patients with asthma for occurrence of ABPM. Patients were te...
Source: European Annals of Allergy and Clinical Immunology - March 6, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Mold Sensitization in Asthmatic and Non-asthmatic Subjects Diagnosed with Extract-Based Versus Component-Based Allergens.
In conclusion, individual fungal sensitization rate was higher in asthmatics compared to non-asthmatics. Extract-based tests, especially SPTs, were most sensitive, but component-based tests covered 80% of extract-based serological sensitization to Alternaria and Aspergillus.
PMID: 30783996 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - February 21, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research
Immune responses to repeated inhalation of Aspergillus versicolor conidia are driven and sustained by innate cell populations
In this study, a subchronic exposure model was used to assess the immunological effects following repeated A. versicolor conidia challenge.
Source: Journal of Allergy and Clinical Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Mark A. Barnes, Tara L. Croston, Angela R. Lemons, Donald H. Beezhold, Brett J. Green Source Type: research
Comparison of Proteomic Profiles Influencing Pulmonary Immune Responses Following Repeated Exposure to Aspergillus and Stachybotrys species
Adverse respiratory health effects have been associated with damp indoor environments and fungal contamination. Comparing molecular profiles following fungal exposures may help identify new biomarkers of fungal exposure.
Source: Journal of Allergy and Clinical Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Tara L. Croston, Mark A. Barnes, Angela R. Lemons, Ajay P. Nayak, Dori Germolec, Donald H. Beezhold, Brett J. Green Source Type: research
Role of < b > < i > Aspergillus fumigatus- < /i > < /b > Specific IgE in the Diagnosis of Allergic Bronchopulmonary Aspergillosis
Conclusions: RoutineA. fumigatus-sIgE screening for asthma patients can significantly improve the diagnostic rate of ABPA.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - January 13, 2019 Category: Allergy & Immunology Source Type: research
Specific IgE Assay for Respiratory Allergens in Patients with Atopy in Ahvaz, Iran.
CONCLUSION: The pattern of allergen-specific IgE showed that Salsola Kali and Lolium perenne are the most common aeroallergens in allergic patients. This finding demonstrates the high frequency of IgE sensitization to outdoor allergens in the southwest of Iran.
PMID: 30593743 [PubMed - in process]
Source: Iranian Journal of Immunology - December 31, 2018 Category: Allergy & Immunology Tags: Iran J Immunol Source Type: research
Molecular study of hypersensitivity to spores in adults and children from Castile & Leon.
CONCLUSIONS: Our results have helped determine which spore molecules are most-closely associated with allergies. Molecular analysis will be useful to determine more accurate and useful immunotherapy in these patients.
PMID: 30578002 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - December 18, 2018 Category: Allergy & Immunology Authors: Armentia A, Martín-Armentia S, Moral A, Montejo D, Martin-Armentia B, Sastre R, Fernández S, Corell A, Fernandez D Tags: Allergol Immunopathol (Madr) Source Type: research
Risk of Invasive Fungal Infections in Patients with High-Risk MDS and AML Receiving Hypomethylating Agents
ConclusionIFI occurred in 9.6% of patients treated with HMA, but was observed in 20.4% of those who were neutropenic on C1D1 of HMA. Another potential risk factor identified was t-MDS versus de novo MDS. Prospective evaluation of mold-active antifungal prophylaxis in patients with MDS or AML who are neutropenic at the start of HMA therapy is warranted.DisclosuresFrey: Novartis: Consultancy; Servier Consultancy: Consultancy. Perl: Arog: Consultancy; NewLink Genetics: Membership on an entity's Board of Directors or advisory committees; Pfizer: Membership on an entity's Board of Directors or advisory committees; Astellas: Con...
Source: Blood - November 21, 2018 Category: Hematology Authors: Kim, G. Y., Burns, J., Freyer, C. W., Hamilton, K., Schuster, M., Frey, N. V., Hexner, E. O., Mangan, J. K., Martin, M. E., McCurdy, S. R., Perl, A. E., Porter, D. L., Luger, S., Loren, A. W. Tags: 637. Myelodysplastic Syndromes-Clinical Studies Source Type: research
Allergic Sensitization Is Associated with Decreased Risk of ED Visits and Hospitalizations for Pain in Sickle Cell Disease
Conclusions: In a population of children with SCD, allergic sensitization was associated with decreased risk of ED visits (total, for pain, and for fever). The mechanism for an association between atopy and a less severe phenotype of SCD is unclear. These findings point to potential differences in immunologic endotype/phenotype and add support to the hypothesis that lower airway disease in children with SCD has a different mechanism than typical childhood atopic asthma. Further investigation into the immunologic phenotypes and mechanisms of lower airway disease in children with SCD is warranted.1All IRR presented are per a...
Source: Blood - November 21, 2018 Category: Hematology Authors: Sadreameli, C., Kopp, B., Creary, S. E., Jacobs, E., Strouse, J. J., McGrath-Morrow, S. A., Casella, J. F., Matsui, E. C. Tags: 114. Hemoglobinopathies, Excluding Thalassemia-Clinical: Poster III Source Type: research
