Rocuronium hypersensitivity: Does off-target occupation of the MRGPRX2 receptor play a role?
Publication date: Available online 10 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Athina L. Van Gasse, Jessy Elst, Chris H. Bridts, Christel Mertens, Margaretha Faber, Margo M. Hagendorens, Luc S. De Clerck, Vito Sabato, Didier G. Ebo (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 12, 2018 Category: Allergy & Immunology Source Type: research

Needs Assessment Survey for a Food Allergy Control Tool
Publication date: Available online 11 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elizabeth Lippner, Scott H. Sicherer, Michael H. Land, Michael Schatz, Chitra Dinakar (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 12, 2018 Category: Allergy & Immunology Source Type: research

C-reactive protein as a diagnostic tool in differential diagnosis of hypereosinophilic syndrome and ANCA-negative eosinophilic granulomatosis with polyangiitis
Publication date: Available online 11 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Amélie Leurs, Cécile Chenivesse, Benjamin Lopez, Jean-Baptiste Gibier, Guillaume Clément, Matthieu Groh, Marie-Christine Copin, Delphine Staumont, Geoffrey Mortuaire, Marie-Hélène Balquet, Frédéric Dezoteux, Nathalie Bautin, Anne-Laure Buchdahl, Noémie Le Gouellec, Nicolas Etienne, Louis Terriou, Sylvain Dubucquoi, Myriam Labalette, Sandrine Morell-Dubois, Hélène Maillard-Lefebvre (Source: The Journal of Allergy and Clinical Imm...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 12, 2018 Category: Allergy & Immunology Source Type: research

Validation of Asthma Control Assessment Among Urban Adolescents Using the Asthma Control and Communication Instrument (ACCI)
ConclusionsThe ACCI, a clinical tool developed to assist communication about asthma control, has demonstrated strong construct validity as a self-reported questionnaire within an urban, African American and Hispanic sample of adolescents. The ACCI has the potential to assist in the assessment of asthma control in urban, minority and/or poor adolescents. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 12, 2018 Category: Allergy & Immunology Source Type: research

Recall urticaria—A new clinical sign in the diagnosis of alpha-gal syndrome
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Paul Schmidle, Klara Reidenbach, Claudia Kugler, Bernadette Eberlein, Tilo Biedermann, Ulf Darsow (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 11, 2018 Category: Allergy & Immunology Source Type: research

New-Onset Asthma in Adults: What Does the Trigger History Tell Us?
Publication date: Available online 18 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Hanneke Coumou, Guus A. Westerhof, Selma B. de Nijs, Marijke Amelink, Elisabeth H. BelBackgroundAdult-onset asthma is an important asthma phenotype and, in contrast to childhood asthma, is often associated with specific triggers of onset. It is unknown whether these triggers correspond with specific phenotypic characteristics or predict a specific asthma outcome.ObjectiveTo compare clinical, functional, and inflammatory characteristics between patients with different triggers of asthma onset, an...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 11, 2018 Category: Allergy & Immunology Source Type: research

Food Protein–Induced Enterocolitis Syndrome Food Challenges: Experience from a Large Referral Center
Conclusions: Our data suggest that our FPIES OFC protocol is safe. Early administration of IVF may prevent the development of hypotension. It is difficult to stratify the risk of severe or delayed reaction based on patient characteristics, and more data are needed to identify those appropriate for home introduction. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 11, 2018 Category: Allergy & Immunology Source Type: research

Asthma-related impact of extending US parents' health insurance coverage to young adults
Publication date: Available online 10 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Joy Hsu, Xiaoting Qin, Maria C. Mirabelli (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 11, 2018 Category: Allergy & Immunology Source Type: research

Is Skin Testing Required Prior to Drug Challenges?
Publication date: Available online 10 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Eric Macy, Luis Felipe Ensina (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 11, 2018 Category: Allergy & Immunology Source Type: research

Does Obesity Increase Respiratory Tract Infections in Patients with Asthma?
ConclusionsBMI classification was not associated with increased risk of RTIs in children or adults. In adults only, obesity was associated with increased URI severity and all-cause and RTI-associated asthma morbidity. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 9, 2018 Category: Allergy & Immunology Source Type: research

The simple 10-item PARC tool to predict childhood asthma – an external validation
ConclusionPerforming equally well in the validation cohort as in the development cohort, PARC is a valid tool for predicting asthma in population based cohorts. Its use in clinical practice is ready to be tested. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 9, 2018 Category: Allergy & Immunology Source Type: research

zxcvbnUS Trends in Mortality Rates for Primary Immunodeficiency Diseases
Publication date: Available online 9 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Evans R. Fernández Pérez, Maya Hunter, Rohit K. Katial (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 9, 2018 Category: Allergy & Immunology Source Type: research

The Impact of Tree Nut Oral Food Challenges on Quality of Life and Acute Reactions in Nut Allergic Patients
Publication date: Available online 9 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jennifer A. Dantzer, Robert A. Wood (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 9, 2018 Category: Allergy & Immunology Source Type: research

Quantifying beta-agonist utilization: Occasions or puffs?
Publication date: Available online 13 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Stanley J. Szefler, Heather E. Hoch, Michael Tuffli, Rahul Gondalia, Meredith A. Barrett, David Van Sickle, David A. Stempel (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 7, 2018 Category: Allergy & Immunology Source Type: research

Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rudolf Valenta, Alexander Karaulov, Verena Niederberger, Yury Zhernov, Olga Elisyutina, Raffaela Campana, Margarete Focke-Tejkl, Mirela Curin, Leyla Namazova-Baranova, Jiu-Yao Wang, Ruby Paw.ar, Musa KhaitovToday, in vivo allergy diagnosis and allergen-specific immunotherapy (AIT) are still based on allergen extracts obtained from natural allergen sources. Several studies analyzing the composition of natural allergen extracts have shown severe problems regarding their quality such as the prese...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Extended analysis of parent and child confidence in recognizing anaphylaxis and using the epinephrine autoinjector during oral food challenges
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Lianne Soller, Timothy Teoh, Ingrid Baerg, Tiffany Wong, Kyla J. Hildebrand, Victoria E. Cook, Catherine M. Biggs, Nicole Lee, Lindsay Yaworski, Scott B. Cameron, Edmond S. Chan (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Does Changing Inhaler Device Impact Real-Life Asthma Outcomes? Clinical and Economic Evaluation
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Chin Kook Rhee, Job F.M. van Boven, Simon Wan Yau Ming, Hye Yun Park, Deog Kyeom Kim, Hae-Sim Park, Joanna Ling Zhi Jie, Kwang-Ha Yoo, David B. PriceBackgroundInhaler usability and deposition differ between devices. Change of device may therefore have an impact on clinical and economic outcomes.ObjectiveTo characterize clinical and economic asthma outcomes surrounding the change from a dry powder inhaler (DPI) to a pressurized metered-dose inhaler (pMDI) for fixed-dose combination inhaled corticost...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Risk of postpartum depression among women with asthma
ConclusionOur findings suggest that women with asthma are more likely to suffer from postpartum depression. A close monitoring of signs of depression for pregnant women with asthma is indicated, allowing prompt and efficient interventions if needed. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Role of skin tests in the diagnosis of immediate hypersensitivity reactions to taxanes. Results of a multicenter study
ConclusionsSkin tests for taxanes seem useful and can be performed in the allergological work-up of subjects with HSRs to these agents, especially in cases of severe reactions with cutaneous involvement. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Drug-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: proportion and determinants of underreporting to pharmacovigilance
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Guillaume Chaby, Bénédicte Lebrun-Vignes, Cynthia Haddad, Francois Hemery, Saskia Ingen-Housz-Oro, Nicolas de Prost, Pierre Wolkenstein, Olivier Chosidow, Laurence Fardet (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

"Desensitization to cross-reacting allergen in egg yolk and chicken meat"
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Manuel Jorge Rial Prado, Marcela Valverde Monge, Aida Gómez Cardeñosa, Rosialzhira Vera Berríos, Carlos Pastor Vargas, Javier Cuesta Herranz (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

Children with Neutrophil-Predominant Severe Asthma Have Proinflammatory Neutrophils With Enhanced Survival and Impaired Clearance
ConclusionsChildren with neutrophil-predominant severe asthma have proinflammatory neutrophils with enhanced survival. Airway macrophages are also proinflammatory and dysfunctional and may contribute to global innate immune impairment. Therapies that target neutrophils and related inflammation may be warranted in this subset of children. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Anaphylaxis to trometamol excipient in gadolinium-based contrast agents for clinical imaging
Publication date: Available online 11 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Joanna Lukawska, Deepal Mandaliya, A.W. Edith Chan, Amy Foggitt, Therese Bidder, Jennifer Harvey, Lisa Stycharczuk, Sotirios Bisdas (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Low resolution rates of seafood allergy
Publication date: Available online 22 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Victoria N. Zotova, Ann Elaine Clarke, Edmond S. Chan, Yuka Asai, Ricky Chin, Chynace Van Lambalgen, Laurie Harada, Moshe Ben-Shoshan (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

A Case of Voriconazole-Induced Pseudoporphyria
Publication date: Available online 25 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Guillermo Rodriguez-Nava, Archi Patel, Dima Youssef, George A. Youngberg, Alexei Gonzalez-Estrada (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

A retrospective analysis of esophageal eosinophilia in patients with aspirin-exacerbated respiratory disease.
Publication date: Available online 25 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Ryan C. Eid, Marina Palumbo, Tanya M. Laidlaw, Kathleen M. Buchheit, Katherine N. Cahill (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Early exposure to cow’s milk protein is associated with a reduced risk of cow’s milk allergic outcomes.
ConclusionExposure to cow’s milk protein in the first 3 months of life was associated with a reduced risk of cow’s milk allergy. These findings are from an observational study and clinical trials are warranted to further assess this association before any recommendations to infant feeding guidelines can be made. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

The Safety of Antibiotic Skin Testing in Severe T-cell-Mediated Hypersensitivity of immunocompetent and immunocompromised hosts
Publication date: Available online 26 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jason A. Trubiano, Abby P. Douglas, Michelle Goh, Monica A. Slavin, Elizabeth J. Phillips (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation
Publication date: Available online 26 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Anne M. Fitzpatrick, Leonard B. Bacharier, Theresa W. Guilbert, Daniel J. Jackson, Stanley J. Szefler, Avraham Beigelman, Michael D. Cabana, Ronina Covar, Fernando Holguin, Robert F. Lemanske, Fernando D. Martinez, Wayne Morgan, Wanda Phipatanakul, Jacqueline A. Pongracic, Robert S. Zeiger, David T. Mauger, NIH/NHLBI AsthmaNetAbstractBackgroundRecurrent preschool wheezing is a heterogeneous disorder with significant morbidity, yet little is known about phenotypic determinants and their impact on...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Long-term Outcome of Peanut Oral Immunotherapy Facilitated Initially by Omalizumab
ConclusionWhile adjunctive omalizumab allowed for faster and successful desensitization in patients with high peanut-IgE, almost half of patients discontinued OIT within 72 months because of reactions. Patients who stopped therapy had higher month 12 peanut-IgE and Arah2-IgE. It is possible that these patients might benefit from longer omalizumab administration. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Exploring the diagnosis and profile of cannabis allergy
ConclusionsThe most effective and practical tests to confirm CA are the SPT with a nCan s 3-rich extract and the sIgE rCan s 3. Can s 3 entails a risk of systemic reactions to plant-derived foods and cofactor-mediated reactions. However, as Can s 3 sensitization is not absolute, other cannabis allergens probably play a role. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Polyethylene Glycol: Not Just a Harmless Excipient
Publication date: Available online 3 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Lucinda Kennard, Krzysztof Rutkowski, Rita Mirakian, Annette Wagner (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Sublingual Swelling due to Sublingual Immunotherapy
Publication date: Available online 3 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Junya Okumura, Naozumi Hashimoto, Yoshinori Hasegawa (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research

Rostrum: Latex Allergy Risks Live On
Publication date: Available online 21 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Kim Liberatore, Kevin J. KellyReduction in the prevalence of IgE-mediated allergy to latex proteins from gloves in patients may lead to lax attention by health care personnel to avoid use of latex products in latex-allergic subjects. Recent evidence from the Pennsylvania Patient Safety Reporting System shows an alarming continuation of adverse events mostly from latex urinary catheters. We are strongly advocating that health care personnel must continue to pay close attention to avoidance of lat...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2018 Category: Allergy & Immunology Source Type: research

Is “Yellow Zone” Management Effective in Reducing Asthma Flares in Children?
Publication date: Available online 21 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Javen Wunschel, Bharat Kumar (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2018 Category: Allergy & Immunology Source Type: research

Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing
Publication date: Available online 20 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Maria J. Torres, N. Franklin Adkinson, Jean-Christoph Caubet, David A. Khan, Mona I. Kidon, Louis Mendelson, Eva Rebelo Gomes, Ticha Rerkpattanapipat, Shuchen Zhang, Eric Macy, AAAAI/WAO 2018 Symposium Penicillin and Cephalosporin Allergy Testing Working GroupAll beta-lactam use is associated with a certain rate of adverse reactions. Many of these adverse reactions result in an allergy to the beta-lactam being entered into the patient's medical record. Unfortunately, only a small minority of the...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Food Protein-Induced Enterocolitis Syndrome Food Challenges: Experience from a Large Referral Center
CONCLUSIONOur data suggests that our FPIES OFC protocol is safe. Early administration of IVF may prevent the development of hypotension. It is difficult to stratify risk of severe or delayed reaction based on patient characteristics and more data is needed to identify those appropriate for home introduction. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort
Publication date: Available online 19 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Reza Yazdani, Hassan Abolhassani, Fatemeh Kiaee, Sima Habibi, Gholamreza Azizi, Marzieh Tavakol, Zahra Chavoshzadeh, Seyed Alireza Mahdaviani, Tooba Momen, Mohammad Gharagozlou, Masoud Movahedi, Amir Ali Hamidieh, Nasrin Behniafard, Mohammamd Nabavi, Mohammad Hassan Bemanian, Saba Arshi, Rasol Molatefi, Roya Sherkat, Afshin Shirkani, Reza AminAbstractBackgroundPredominantly antibody deficiencies (PADs) are the most common primary immunodeficiencies, characterized by hypogammaglobulinemia and ina...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Predictors of inhaled corticosteroid taper failure in adults with asthma
Publication date: Available online 19 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Juan Carlos Cardet, Christopher D. Codispoti, Tonya S. King, Leonard Bacharier, Tara Carr, Mario Castro, Vernon Chinchilli, Ryan Dunn, Fernando Holquin, Linda Engle, Kyle Nelson, Victor E. Ortega, Michael Peters, Sima Ramratnam, Jerry A. Krishnan, Michael E. Wechsler, Elliot Israel, NHLBI Asthmanet (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Initiating yellow jacket venom immunotherapy with a 100-μg dose: A challenge?
Publication date: Available online 19 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Byrthe J.P.R. Vos, Anthony E.J. Dubois, Michèle M. Rauber, Wolfgang Pfützner, Michaela Miehe, Barbara Bohle, Christian Möbs, Joanne N.G. Oude Elberink (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Antibiotic allergy labels in children are associated with adverse clinical outcomes
Publication date: Available online 19 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Michaela Lucas, Annabelle Arnold, Aine Sommerfield, Michelle Trevenen, Laure Braconnier, Alina Schilling, Fuad Abass, Lliana Slevin, Brittany Knezevic, Christopher Blyth, PhD. Kevin Murray, Britta von Ungern-Sternberg, Kristina RueterAbstractBackgroundSelf-reported antibiotic allergies are common among hospitalised adults and children. There is a paucity of studies investigating the impact of an antibiotic allergy label in childhood.ObjectiveTo investigate the impact of antibiotic allergy labell...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

New-onset asthma in adults; what does the trigger history tell us?
Conclusionpatients with adult-onset asthma can be characterized by the trigger that seemingly incited their asthma. These triggers might represent underlying mechanisms and may be important to phenotype patients and predict disease outcome. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 19, 2018 Category: Allergy & Immunology Source Type: research

Self-reported anaphylaxis to packaged foods in Australia
Publication date: Available online 18 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Giovanni A. Zurzolo, Katrina J. Allen, Rachel L. Peters, Shyamali C. Dharmage, Mimi L.K. Tang, Maria Said, Michael Field, Maximilian de Courten, Michael L. Mathai, Dianne E. Campbell (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 19, 2018 Category: Allergy & Immunology Source Type: research

Quantifying beta agonist utilization: occasions or puffs?
Publication date: Available online 13 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Stanley J. Szefler, Heather Hoch, Michael Tuffli, Rahul Gondalia, Meredith A. Barrett, David Van Sickle, David A. Stempel (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 13, 2018 Category: Allergy & Immunology Source Type: research

Uncharted Waters: Challenges in the Era of Biologic Therapies for Nasal Polyposis
Publication date: Available online 11 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jayant M. Pinto, Fuad M. Baroody, Robert M. NaclerioSeveral new, promising, targeted therapies for nasal polyposis are being tested in large-scale clinical trials. These agents target pathways thought to be involved in the disease, including IgE, IL-5, IL-4/IL-13, and others. Designing these trials poses significant challenges: who and when to enroll is not completely clear, optimal dosing is not known, outcome measures are insufficiently robust, there are no validated biomarkers, trial regimens...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 12, 2018 Category: Allergy & Immunology Source Type: research

Anaphylaxis to trometamol excipient in gadolinium based contrast agents for clinical imaging.
Publication date: Available online 11 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Joanna Lukawska, Deepal Mandaliya, A.W. Edith Chan, Amy Foggitt, Therese Bidder, Jennifer Harvey, Lisa Stycharczuk, Sotirios Bisdas (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 12, 2018 Category: Allergy & Immunology Source Type: research

Reslizumab Compared with Benralizumab in Patients with Eosinophilic Asthma: A Systematic Literature Review and Network Meta-Analysis
ConclusionsThis indirect comparison suggests reslizumab may be more efficacious than benralizumab in patients with eosinophilic asthma in GINA step 4/5 with elevated blood eosinophil levels (benralizumab, ≥300/μL; reslizumab, ≥400/μL) and ≥2 exacerbations in the previous year. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 12, 2018 Category: Allergy & Immunology Source Type: research

Is there an overlap in immune response between allergic bronchopulmonary and chronic pulmonary aspergillosis?
Publication date: Available online 8 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Inderpaul Singh Sehgal, Hansraj Choudhary, Sahajal Dhooria, Ashutosh Nath Aggarwal, Mandeep Garg, Arunaloke Chakrabarti, Ritesh AgarwalABSTRACTBackgroundChronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA) are presumed to represent two distinct manifestations of Aspergillus species in the lung.ObjectiveTo investigate any possible overlap of the immunological tests used for diagnosing ABPA in proven cases of CPA.MethodsIn consecutive subjects with CPA, we calcul...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 9, 2018 Category: Allergy & Immunology Source Type: research

Fixed Drug Eruption Due to Chlorhexidine Mouthwash Confirmed by Lesional Patch Testing
Publication date: Available online 8 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Timothy J. Watts, David Thursfield, Rubaiyat Haque (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 9, 2018 Category: Allergy & Immunology Source Type: research

Mycoplasma-Induced Toxic Epidermal Necrolysis with Severe Mucositis
Publication date: Available online 7 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Ze-Hu Liu, Hong Shen (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 8, 2018 Category: Allergy & Immunology Source Type: research