Low caregiver health literacy among pediatric food-allergic patients is associated with poorer food allergy management knowledge
Publication date: Available online 11 July 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Maureen Egan, H. Shonna Yin, Matthew Greenhawt, Julie Wang (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 11, 2018 Category: Allergy & Immunology Source Type: research

Common food flavors are safe in patients with urticaria or atopic dermatitis
Publication date: Available online 10 July 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Viktor Schnabel, Peter Schupp, Carsten Gutgesell, Andrea Braun, Michael P. Schön, Thomas Fuchs, Timo Buhl (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 11, 2018 Category: Allergy & Immunology Source Type: research

Immediate local and systemic hypersensitivity due to etanercept and adalimumab
Publication date: Available online 10 July 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Katharina Hansel, Leonardo Bianchi, Marta Tramontana, Anna Balato, Emanuele Scala, Jacopo Brozzi, Luca Stingeni (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 11, 2018 Category: Allergy & Immunology Source Type: research

The Allergic Rhinitis Control Test Questionnaire Is Valuable in Guiding Step-Down Pharmacotherapy Treatment of Allergic Rhinitis
Publication date: Available online 7 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rongfei Zhu, Jingru Wang, Yuying Wu, Yongshi Yang, Nan Huang, Yaqi Yang, Rui Zhang, Dongxia Ma, Lin Yang, Pascal DemolyBackgroundAllergic Rhinitis Control Test (ARCT) has been validated in the allergic rhinitis (AR) step-up pharmacotherapy management approach.ObjectiveThe aim of our study was to evaluate the potential of ARCT in AR step-down pharmacotherapy.MethodsIn an open-labeled randomized controlled study, patients with AR controlled with intranasal corticosteroid (INS) plus antihistamine (step 4...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Successful haploidentical transplantation with post-transplant cyclophosphamide for activated phosphoinositide 3-kinase δ syndrome
Publication date: Available online 8 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Che Ry Hong, Sangmoon Lee, Kyung Taek Hong, Jung Yoon Choi, Hee Young Shin, Murim Choi, Hyoung Jin Kang (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Prevalence of patients eligible for anti-IL-5 treatment in a cohort of adult-onset asthma
ConclusionsIn a cohort of unselected consecutive patients with adult-onset asthma, 5.9% fulfilled criteria for severe asthma and 2% qualified for anti-IL-5 treatment. Both groups represent a high burden to healthcare and specifically targeted treatment could lead to lower use of healthcare at long-term. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Kounis syndrome caused by anaphylaxis without skin manifestations after cefazolin administration
Publication date: Available online 11 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Hidenori Adachi, Madoka Ihara, Yuhei Nojima, Tetsuya Kurimoto, Sinsuke Nanto (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Eosinophil-Related Disease and the Skin
Publication date: Available online 12 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Kristin M. Leiferman, Margot S. PetersAbstractEosinophils are bone marrow-derived cells that infiltrate skin and mucous membrane in a broad spectrum of primary and reactive inflammatory diseases and malignancies. The eosinophil has potent proinflammatory activities, particularly, through the effects of its toxic granule proteins. In addition, eosinophils have prothrombotic and profibrotic activities. Eosinophil participation in the pathogenesis of certain diseases without identifiable intact eosinoph...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Pemetrexed anaphylaxis—an unusual suspect
Publication date: Available online 13 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Leonor Carneiro-Leão, Vladyslava Barzylovych, Josefina Cernadas (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Anaphylaxis after vaccination in a pediatric patient: further implicating alpha-gal allergy
Publication date: Available online 15 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Cosby A. Stone, Scott P. Commins, Shailesh Choudhary, Chandra Vethody, Jill L. Heavrin, Jared Wingerter, Jonathan A. Hemler, Kenneth Babe, Elizabeth J. Phillips, Allison E. Norton (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Myths of Exposure
Publication date: Available online 15 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Karin A. Pacheco (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

An Infant with Suppurative Adenitis, Nonhealing Wound, and Perianal Sinus
Publication date: Available online 19 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Pandiarajan Vignesh, Amit Rawat, Anju Gupta (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Goals and Motivations of Families Pursuing Oral Immunotherapy for Food Allergy
Publication date: Available online 21 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Joan H. Dunlop, Corinne A. Keet (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Development and validation of personalised prediction to estimate future risk of severe exacerbations and uncontrolled asthma in patients with asthma, using clinical parameters and early treatment response
ConclusionWe developed and externally validated a risk prediction score, quantifying both level of current asthma control and the guideline-defined future risk. Patients’ individual risk can now be estimated in an easy way, as proposed but not specified, by asthma management guidelines. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Differential expression of alarmins: Interleukin-33 as a candidate marker for early diagnosis of TEN
Publication date: Available online 21 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Akimasa Adachi, Mayumi Komine, Hidetoshi Tsuda, Saeko Nakajima, Kenji Kabashima, Mamitaro Ohtsuki (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Clindamycin anaphylaxis confirmed by in vivo and in vitro testing
Publication date: Available online 22 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Didier G. Ebo, Christel Mertens, Marissa Braes, Isabel Mennes, Chris H. Bridts, Vito Sabato (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Trimethoprim-sulfamethoxazole induces acute pancreatitis associated with drug-specific cytotoxic T lymphocytes
Publication date: Available online 22 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Minyoung Jung, Jihyun Kim, Ji Young Lee, Minji Kim, Seung-Hyun Kim, Kangmo Ahn (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Hereditary angioedema: Clinical presentation and socioeconomic cost of 200 French patients
Publication date: Available online 22 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Nicolas Javaud, Laurence Bouillet, Hasina Rabetrano, Alexandre Bitoun, David Launay, Frederic Lapostolle, Paul-Georges Reuter, Ludovic Martin, Eric Vicaut, Olivier Fain, Frederic Adnet, Isabelle Durand-zaleski, Bernard Floccard, Anne Gompel, Alain Sobel, Isabelle Boccon-Gibod, Brigitte Coppere, Gisele Kanny (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Eosinophilic Esophagitis Is a Late Manifestation of the Allergic March
ConclusionsAllergic comorbidities are positively associated with EoE diagnosis. Together, our findings suggest that EoE is a late manifestation of the allergic march. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Drug-induced Anaphylaxis Documented in Electronic Health Records
Publication date: Available online 30 June 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Neil Dhopeshwarkar, Aziz Sheikh, Raymond Doan, Maxim Topaz, David W. Bates, Kimberly G. Blumenthal, Li ZhouAbstractBackgroundAlthough drugs represent a common cause of anaphylaxis, few large studies of drug-induced anaphylaxis have been performed.ObjectiveTo describe the epidemiology and validity of reported drug-induced anaphylaxis in the electronic health records (EHRs) of a large United States healthcare system.MethodsUsing EHR drug allergy data from 1995-2013, we determined the population prevale...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Two ideas to improve mite allergen avoidance
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Euan R. Tovey (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

A favorable response to omalizumab in a patient with cheilitis granulomatosa
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Eustachio Nettis, Elisabetta Di Leo, Maria Bisaccia, Carolina Marasco, Caterina Foti, Angelo Vacca (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Recurrent Angioedema
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Dennis K. Ledford, Timothy J. Craig (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

On-Demand Intranasal Corticosteroids for Treatment of Seasonal Allergic Rhinitis in Children
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Allison Hicks, Maureen Egan (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Delayed Unblinding of Double-Blind Placebo-Controlled Food Challenges in Anxious Patients Allows Exclusion of Both Immediate and Delayed Adverse Reactions to Food
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Victoria E. Cook, Sharon To, Lianne Soller, Edmond S. Chan (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Wheat-dependent exercise-induced anaphylaxis: Are you sure about the diagnosis?
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): George N. Konstantinou (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Reply
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Morten Junker Christensen, Esben Eller, Charlotte Gotthard Mortz, Knut Brockow, Carsten Bindslev-Jensen (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Reply
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Jeffrey M. Wilson, Thomas A.E. Platts-Mills (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Cover 1
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Table of Contents
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Highlights Page
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Editorial Board
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Information for Readers
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Practice Notes from the AAAAI
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Continuing Medical Education Calendar
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Chronic Spontaneous Urticaria: The Devil's Itch
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Sarbjit S. Saini, Allen P. KaplanChronic urticaria is defined as the presence of urticaria for a period exceeding 6 weeks, assuming symptoms for most days of the week. It is divided into chronic inducible urticarias and chronic spontaneous urticaria, previously termed chronic idiopathic urticaria. The latter designation emphasizes that patients can experience urticaria independent of any exogenous stimulus even if one can define circumstances that may worsen symptoms. A search for such an...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

CME Exam: Chronic Spontaneous Urticaria: The Devil's Itch
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Emerging Biomarkers and Therapeutic Pipelines for Chronic Spontaneous Urticaria
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Gustavo Deza, Peter A. Ricketti, Ana M. Giménez-Arnau, Thomas B. CasaleChronic spontaneous urticaria (CSU) is defined as the appearance of evanescent wheals, angioedema, or both, for at least 6 weeks. CSU is associated with intense pruritus and poor quality of life, with higher odds of reporting depression, anxiety, and sleep difficulty. As of yet, the assessment of the activity and course of the disease along with the response to several treatments in CSU are based purely on the p...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

CME Exam: Emerging Biomarkers and Therapeutic Pipelines for Chronic Spontaneous Urticaria
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

How to Approach Chronic Inducible Urticaria
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Marcus Maurer, Joachim W. Fluhr, David A. KhanChronic inducible urticaria (CIndU) is a group of chronic urticarias characterized by the appearance of recurrent wheals, recurrent angioedema or both, as a response to specific triggers. CIndU includes both physical (symptomatic dermographism, cold and heat urticaria, delayed pressure urticaria, solar urticaria, and vibratory urticaria) and nonphysical urticarias (cholinergic urticaria, contact and aquagenic urticaria). Here, we review the di...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

CME Exam: How to Approach Chronic Inducible Urticaria
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Angioedema Due to Bradykinin Dysregulation
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Marco Cicardi, Bruce L. ZurawAngioedema is an acute swelling of the deeper layers of the skin or mucosa resulting from a transient increase in vascular permeability. Angioedema can occur in the absence or presence of hives, be hereditary or acquired, and be caused by various potential mediators, including histamine and bradykinin. Bradykinin-mediated angioedema can be difficult to diagnose but is responsible for a disproportionate percentage of the serious morbidity and mortality associat...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

CME Exam: Angioedema Due to Bradykinin Dysregulation
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

A Comparison of the United States and International Perspective on Chronic Urticaria Guidelines
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Torsten Zuberbier, Jonathan A. BernsteinUrticaria is a heterogeneous skin disorder that may be acute or chronic and is defined by the appearance of wheals, angioedema, or both. The European perspective is expressed in a recent international guideline and the American perspective has been based on the US Joint Task Force chronic urticaria practice parameter published in 2014. Both the international guideline (initiated by the European societies European Academy of Allergology and Clinical ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Management of Pediatric Urticaria with Review of the Literature on Chronic Spontaneous Urticaria in Children
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Moshe Ben-Shoshan, Clive E. GrattanThere are substantial knowledge gaps related to diagnosis and management of pediatric cases of chronic urticaria, and in particular chronic spontaneous urticaria (CSU). In this article we aimed to review the diagnosis and management of chronic urticaria in children and CSU in particular. We conducted a systematic review of articles published in English and French on pediatric CSU management in the last 10 years. We included experimental studies (eg, rand...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Mimickers of Urticaria: Urticarial Vasculitis and Autoinflammatory Diseases
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Mark D.P. Davis, Jeroen C.H. van der HilstA wide differential diagnosis must be considered in a patient presenting with urticarial plaques. Although acute and chronic urticaria are the commonest diagnoses, other differential diagnoses include polymorphous eruption of pregnancy, mast cell disorders, hypereosinophilic syndrome, urticarial vasculitis, pemphigoid, systemic lupus erythematosus, and autoinflammatory disease. This review will specifically address urticarial vasculitis and autoin...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Decoding the Enigma of Urticaria and Angioedema
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): David P. Huston, Vito Sabato (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

In Vitro Diagnosis of Immediate Drug Hypersensitivity During Anesthesia: A Review of the Literature
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Didier G. Ebo, Margaretha Faber, Jessy Elst, Athina L. Van Gasse, Chris H. Bridts, Christel Mertens, Luc S. De Clerck, Margo M. Hagendorens, Vito SabatoQuantification of specific IgE (sIgE) antibodies constitutes an important measure to document anesthesia-related immediate hypersensitivity reactions (IHRs). However, only a few drug-specific assays are available and their predictive value is not known. In cases of non-IgE mediated IHRs, diagnosis might benefit from cellular tests such as ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

The Urticaria Activity Score—Validity, Reliability, and Responsiveness
Publication date: July–August 2018Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 4Author(s): Tomasz Hawro, Tatevik Ohanyan, Nicole Schoepke, Martin Metz, Adriane Peveling-Oberhag, Petra Staubach, Marcus Maurer, Karsten WellerBackgroundChronic spontaneous urticaria is characterized by fluctuating symptoms. Its activity is assessed with the urticaria activity score (UAS). Two versions of the urticaria activity score used for 7 consecutive days (UAS7) are available: (1) The guideline-recommended UAS7, with once-daily documentation, and (2) the UAS7TD, with twice-daily documentation....
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research

Predicting Chronic Spontaneous Urticaria Symptom Return After Omalizumab Treatment Discontinuation: Exploratory Analysis
ConclusionsThese results suggest that the probability of rapid symptom return in patients with CSU who discontinue treatment with omalizumab can be estimated based on baseline UAS7 and early treatment response. (Source: The Journal of Allergy and Clinical Immunology: In Practice)
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research