The Protective Effects of < b > < i > Helicobacter pylori < /i > < /b > Infection on Allergic Asthma
As an ancient Gram-negative bacterium,Helicobacter pylori has settled in human stomach. EradicatingH. pylori increases the morbidities of asthma and other allergic diseases. Therefore,H. pylori might play a protective role against asthma. The “disappearing microbiota” hypothesis suggests that the absence of certain types of the ancestral microbiota could change the development of immunology, metabolism, and cognitive ability in our early life, contributing to the development of some diseases. And the Hygiene Hypothesis links early en vironmental and microbial exposure to the prevalence of atopic allergies and a...
Source: International Archives of Allergy and Immunology - October 20, 2020 Category: Allergy & Immunology Source Type: research

Chronic Granulomatous Disease: A Perspective from a Developing Nation
Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 15, 2020 Category: Allergy & Immunology Source Type: research

Change in Allergy Practice during the COVID-19 Pandemic
Conclusions: Allergists in Turkey have been using telemedicine at a high rate during the COVID-19 pandemic for asthma and rhinitis. The continuation rate of SCIT was low while the discontinuation rate of biologicals and systemic steroid use in asthma was high in Turkey.Our study results and learning from the experiences of other countries and specialties may help to optimize allergy practice and compatibility with international guidelines.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 15, 2020 Category: Allergy & Immunology Source Type: research

Baked Tolerance in Cow ’s Milk Allergy: Quite Frequent, Hard to Predict!
Conclusions: The high percentage of patients able to tolerate baked goods enables an improvement in intake possibilities and quality of life of CMA patients and families. Specific CM IgE and casein SPT demonstrated to be useful predictors in relation to baked milk tolerance.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 14, 2020 Category: Allergy & Immunology Source Type: research

Reconstitution of IgG Subclasses Following Immunoglobulin Administration in Adult Patients with Common Variable Immune Deficiency
Conclusions: Incomplete IgG subclass reconstitution was associated with increased frequency of infections. IgG trough levels correlate with IgG subclass reconstitution. A limited number ofS. pneumoniae serotype antibodies are commonly impaired in CVID.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 14, 2020 Category: Allergy & Immunology Source Type: research

Formation of IgE-Allergen-CD23 Complex Changes in Children Treated with Subcutaneous Immunotherapy for Japanese Cedar Pollinosis
Conclusion: The ability of IgE-allergen complexes to bind to CD23 decreased after SCIT, suggesting that increasing levels of IgE-blocking antibodies, including IgG4, may play an important role in the mechanism of SCIT.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 8, 2020 Category: Allergy & Immunology Source Type: research

Comment on: Predictive and Diagnostic Value of Nasal Nitric Oxide in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps
Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 8, 2020 Category: Allergy & Immunology Source Type: research

Evaluation of the Diagnostic Accuracy of Thymus and Activation-Regulated Chemokine to Discriminate Food Protein-Induced Enterocolitis Syndrome from Infectious Gastroenteritis
Conclusion: In the absence of eczema, post-emetic serum TARC levels might be a potential diagnostic biomarker for distinguishing FPIES from infectious gastroenteritis.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - October 6, 2020 Category: Allergy & Immunology Source Type: research

The Gut Microbiome of Adults with Allergic Rhinitis Is Characterised by Reduced Diversity and an Altered Abundance of Key Microbial Taxa Compared to Controls
Conclusion: Adult AR sufferers have a distinct gut microbiome profile, marked by a reduced microbial diversity and altered abundance of certain microbes compared to controls. The results of this study provide evidence that unique gut microbial patterns occur in AR sufferers in adulthood and warrant further examination in the form of mechanistic studies.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 24, 2020 Category: Allergy & Immunology Source Type: research

Elevated Serum Level of CD48 in Patients with Intermittent Allergic Rhinitis
Conclusions: sCD48 may be a biomarker to the exacerbation phase in patients with IAR. One can assume that CD48 participates in the pathogenesis of IAR.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 23, 2020 Category: Allergy & Immunology Source Type: research

Does Asthma Increase the Mortality of Patients with COVID-19?: A Systematic Review and Meta-Analysis
The purpose of this systematic review and meta-analysis was to explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma. The databases PubMed, Scopus, Embase, Google Scholar, and medRxiv.org were searched for studies comparing the clinical outcomes of asthmatic patients with those of nonasthmatic patients diagnosed with COVID-19. Mortality data were summarized using the Mantel-Haenszel OR with 95% CI in a random-effects model. Five retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 non...
Source: International Archives of Allergy and Immunology - September 22, 2020 Category: Allergy & Immunology Source Type: research

Effect of the Use of Intranasal Spray of Essential Oils in Patients with Perennial Allergic Rhinitis: A Prospective Study
Conclusion: A hypertonic EO-based nasal spray could be a new and natural option in the management of PAR. It could also be used as an add-on therapy when nasal symptoms are not fully controlled.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 22, 2020 Category: Allergy & Immunology Source Type: research

Descriptive Analysis of Cross-Reactive Anaphylaxis as a Different Clinical Subtype of Nonsteroidal Anti-Inflammatory Drug (NSAID) Hypersensitivity
Conclusion: In the present study, NSAID cross-anaphylaxis was more frequent in women, and acetylsalicylic acid and dipyrone were the main triggers. Rhinitis was the main allergic comorbidity, and there was a high incidence of atopy. The majority tolerated selective COX-2 NSAIDs.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 21, 2020 Category: Allergy & Immunology Source Type: research

Characteristics and Contributing Factors Related to Nonsteroidal Anti-Inflammatory Drugs Hypersensitivity
Conclusion: Angioedema was the most typical symptom, and propionic acid derivatives were the most frequently reported culprit drugs. The significant risk factors predicting NSAID hypersensitivity were personal history of AR/CRS, onset of NSAID hypersensitivity reaction over 15 years old, and immediate reaction.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 18, 2020 Category: Allergy & Immunology Source Type: research

Predisposition to Hyperthyroidism May Be Influenced by Functional < b > < i > TNF- α < /i > < /b > , < b > < i > IL-1 < /i > < /b > , < b > < i > IL-6 < /i > < /b > , and < b > < i > IL-10 < /i > < /b > Polymorphisms: A Meta-Analysis
Conclusions: This meta-analysis suggests thatTNF- α−308 G/A,IL-1A−889 C/T,IL-1B−511 C/T,IL-6−174 G/C,IL-6−572 G/C,IL-10−819 C/T, andIL-10−1,082 A/G polymorphisms may influence predisposition to hyperthyroidism in certain ethnic groups.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 17, 2020 Category: Allergy & Immunology Source Type: research

Value of Component Resolved Diagnostics to < b > < i > Aspergillus fumigatus < /i > < /b > in Patients with Upper Airway Complaints
Conclusions: Component resolved diagnostic testing toward the major allergen Asp f 1 was less sensitive than skin prick test and serology toAspergillus fumigatus protein extract. However, sensitivity of component resolved diagnostics might be underestimated. Diagnostics of the species-specific allergens Asp f 1, 2, and 4 might allow to differentiate between genuine and cross-reactive sensitization. In the clinical routine, skin prick test and serology to crude extract remain the methods of choice.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 17, 2020 Category: Allergy & Immunology Source Type: research

Risk Factors for Safety of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis
A good compliance often attributes to good efficacy and safety of sublingual immunotherapy (SLIT). However, few studies have been conducted on the safety of SLIT treatment in children. We aimed to confirm the pretreatment parameters to predict the safety in children who underwent SLIT. 601 children with allergic rhinitis (AR) treated with SLIT were enrolled in this study. Baseline clinical information and laboratory parameters were collected. The clinical response and adverse events (AEs) were recorded and evaluated. A multivariate logistic regression model was established to confirm the predictors for AEs. The AEs were re...
Source: International Archives of Allergy and Immunology - September 16, 2020 Category: Allergy & Immunology Source Type: research

The Connection between Urinary Equol Levels and the Prevalence of Atopic Dermatitis
Conclusion: Equol levels in childhood might be involved in the development of atopic dermatitis.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 15, 2020 Category: Allergy & Immunology Source Type: research

Mite Molecular Profile in the Th2-Polarized Moderate-to-Severe Persistent Asthma Endotype Subjected to High Allergen Exposure
Conclusions and Clinical Relevance: The proposed CRD panel approach, containing the most prevalent HDM allergens, appeared to be sufficient to obtain a preciseD. pteronyssinus molecular diagnosis in asthmatics with a climate-dependent high-mite allergen exposure and coexisting sensitization. A dominant role of both major and mid-tier allergens has been confirmed in moderate and severe persistent asthmatics with the preponderant Th2-high endotype.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 14, 2020 Category: Allergy & Immunology Source Type: research

Sensitization to Local Seafood Allergens in Adult Patients with Atopic Dermatitis in Malaysia
Conclusion: The relevant sensitization rate of local seafood among adults with AD was 45.1%.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 14, 2020 Category: Allergy & Immunology Source Type: research

Predictive Significance of Charcot-Leyden Crystal Protein in Nasal Secretions in Recurrent Chronic Rhinosinusitis with Nasal Polyps
Conclusions: CLC protein in nasal secretions may serve as a promising noninvasive biomarker to predict CRSwNP recurrence.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 14, 2020 Category: Allergy & Immunology Source Type: research

Inventory of the Recommendations for Patients with Pollen Allergies and Evaluation of Their Scientific Relevance
Pollens are responsible for allergic rhinitis, conjunctivitis, and asthma. The incidence of these diseases, which have adversely impacted the social and professional lives of people who are allergic to pollen, has tripled in the past 25 years. Official institutes, health care institutions, public interest groups, and mainstream news media provide people who are allergic to pollen with advice aimed at reducing their symptoms. The aim of this work was to provide an inventory of the prevention guidelines in the world and to evaluate their scientific relevance. A PubMed search was carried out using specific keywords. The scien...
Source: International Archives of Allergy and Immunology - September 10, 2020 Category: Allergy & Immunology Source Type: research

A Comparative Analysis of Allergen Proteins between Plants and Animals Using Several Computational Tools and Chou ’s PseAAC Concept
Conclusions: The results indicated that bioinformatics-based studies could be useful in comparing plant and animal allergens.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 9, 2020 Category: Allergy & Immunology Source Type: research

Acquired Angioedema due to C1 Inhibitor Deficiency Preceding Splenic Marginal Zone Lymphoma: Further Insights from Clinical Practice
Conclusions: Close follow-up, including detailed clinical history, physical examination, and laboratory tests, of our patients with AAE-C1-INH was essential for the early diagnosis and successful treatment of the lymphoproliferative disease, leading to the resolution of the angioedema attacks.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - September 7, 2020 Category: Allergy & Immunology Source Type: research

Immunological and Symptomatic Effects of Oral Intake of Transgenic Rice Containing 7 Linked Major T-Cell Epitopes from Japanese Cedar Pollen Allergens
Conclusions: Allergen-specific T-cell responses were significantly reduced by oral intake of transgenic rice in a dose-dependent manner. However, neither medication score nor QOL symptom scores could be improved during the JC pollen season with oral intake of transgenic rice for 20 weeks.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 27, 2020 Category: Allergy & Immunology Source Type: research

Identification of Seasonal Variations of Antibodies against PR-10-Specific Epitopes Can Be Improved Using Peptide-Phage Display
Conclusions: Peptide phage display data suggest an impact of birch and hazel pollen exposure on the recognition pattern of Bet v 1-like allergen epitopes. Epitope-oriented analyses could provide deeper, personalized details regarding the allergen epitope recognition influenced by pollen exposure beyond the capability of current methods.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 26, 2020 Category: Allergy & Immunology Source Type: research

Lysophosphatidic Acid Regulates the Differentiation of Th2 Cells and Its Antagonist Suppresses Allergic Airway Inflammation
Conclusion: These findings suggest that LPA plays an important role in allergic airway inflammation and that the blockade of LPA2 might have therapeutic potential for bronchial asthma.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 26, 2020 Category: Allergy & Immunology Source Type: research

Effect of Specific Immunoglobulin E Response and Comorbidities on Effectiveness of MP-AzeFlu in a Real-Life Study
Conclusion: MP-AzeFlu treatment reduced VAS severity and quality-of-life scores from baseline in the total population and ARPs, supporting MP-AzeFlu as an effective treatment for all patients with moderate-to-severe AR, regardless of AR phenotype or comorbidities.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 21, 2020 Category: Allergy & Immunology Source Type: research

Eosinophil/Neutrophil/Platelet-to-Lymphocyte Ratios in Various Types of Immediate Hypersensitivity to NSAIDs: A Preliminary Study
Conclusions: The ELR and PLR may be useful in differentiating various types of immediate hypersensitivity to NSAIDs. Moreover, the ELR may be helpful in differentiating patients with bronchial asthma with and without NSAID hypersensitivity and PLR in differentiating patients with chronic spontaneous urticaria from NECD.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 19, 2020 Category: Allergy & Immunology Source Type: research

Dietary Vitamin D Supplementation Is Ineffective in Preventing Murine Cow ’s Milk Allergy, Irrespective of the Presence of Nondigestible Oligosaccharides
Conclusions: High-dose VitD supplementation in mice does not protect against CMA development in the presence or absence of GFA.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 19, 2020 Category: Allergy & Immunology Source Type: research

CD8 Treg Cells Inhibit B-Cell Proliferation and Immunoglobulin Production
Conclusion: CD8 Treg regulate B-cell responses, and CD183+CD25highCD278+CD8 Treg are more powerful regulators of B-cell proliferation and immunoglobulin production than CD183+CD197+CD45RA −CD8 Treg and, therefore, may be used as preferred markers for CD8 Treg.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 14, 2020 Category: Allergy & Immunology Source Type: research

The Effect of Bronchoconstriction by Methacholine Inhalation in a Murine Model of Asthma
Conclusions: Repeated bronchoconstriction caused by methacholine inhalation elicited allergic airway inflammation and airway remodeling.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 13, 2020 Category: Allergy & Immunology Source Type: research

Supplementation with Tetrahydrocurcumin Enhances the Therapeutic Effects of Dexamethasone in a Murine Model of Allergic Asthma
Conclusions: Supplementation with THC can enhance the therapeutic effects of DEX to alleviate airway symptoms, lung inflammation, and the Th2 response. Our findings suggest that dietary administration of THC could act as an add-on therapy for asthma treated with GCs.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 12, 2020 Category: Allergy & Immunology Source Type: research

Comparison of the Safety Profiles of 3 Different Hymenoptera Venom Immunotherapy Protocols: A Retrospective 2-Center Study of 143 Patients
Conclusion: Accelerated VIT protocols, namely, rush and ultra-rush protocols are safe therapeutic options for Hymenoptera venom-allergic patients and displayed fewer SR than cluster VIT protocols in our study.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 11, 2020 Category: Allergy & Immunology Source Type: research

Predisposition of Inflammatory Bowel Disease Is Influenced by < b > < i > IL-8 < /i > < /b > , < b > < i > IL-10 < /i > < /b > , and < b > < i > IL-18 < /i > < /b > Polymorphisms: A Meta-Analysis
Conclusions: The present meta-analysis shows thatIL-8 rs4073,IL-10 rs1800871,IL-10 rs1800872,IL-10 rs1800896, andIL-18 rs1946518 polymorphisms may influence predisposition of IBD. Furthermore,IL-18 rs187238 polymorphism may influence predisposition of CD, but not predisposition of ulcerative colitis.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 11, 2020 Category: Allergy & Immunology Source Type: research

A Retrospective Clinical Audit of the ImmunoCAP ISAC 112 for Multiplex Allergen Testing
Conclusions: A prospective research study is necessary to further investigate the clinical utility and cost-effectiveness of the ISAC. A UK national registry would be of great benefit but will require a large resource base.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 11, 2020 Category: Allergy & Immunology Source Type: research

AERD Associated Nasal Polyposis: Efficacy of Postoperative Antileukotriene Therapy in Comparison with Aspirin Desensitization. A Retrospective Study
Conclusion: Postoperative treatment with leukotriene-receptor-antagonists and aspirin desensitization both significantly reduce nasal polyp recurrence. MT has a positive effect on subjective sinonasal outcomes and patients ’ quality of life over time.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 10, 2020 Category: Allergy & Immunology Source Type: research

Plasma P-Selectin Is Inversely Associated with Lung Function and Corticosteroid Responsiveness in Asthma
Conclusions: High BPS is associated with airway obstruction, air trapping, the “severe fixed-airflow” cluster, and lack of FEV1 improvement in response to TA injection. P-selectin concentration, which is a stable trait with only modest elevation during exacerbation, may be a useful biomarker for a severe asthma pheno- or endotype characterized by low pulmonary function and lack of corticosteroid responsiveness.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 10, 2020 Category: Allergy & Immunology Source Type: research

Potential Differences between Local and Systemic Allergic Rhinitis Induced by Birch Pollen
Conclusion: These obtained data suggest there are no potential mechanisms that could explain LAR compared to SAR.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 7, 2020 Category: Allergy & Immunology Source Type: research

Sleep Patterns and Development of Children with Atopic Dermatitis
Conclusion: Boys with moderate-severe AD within the first 3 months of diagnosis were at increased risk for sleep problems. Children with AD who have multiple siblings and sleep problems should be evaluated for developmental delay and monitored closely.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - August 7, 2020 Category: Allergy & Immunology Source Type: research

Personalized Approach of Severe Eosinophilic Asthma Patients Treated with Mepolizumab and Benralizumab
Conclusions: This real-life study provides new insights for the personalized approach to severe asthma therapy. Although preliminary, the results indicate that besides eosinophils, KL-6 and sL-selectin are useful as biomarkers of early response that can also involve in the pathogenesis of severe asthma.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 30, 2020 Category: Allergy & Immunology Source Type: research

Increased Serum Periostin Levels and Eosinophils in Nasal Polyps Are Associated with the Preventive Effect of Endoscopic Sinus Surgery for Asthma Exacerbations in Chronic Rhinosinusitis Patients
Conclusion: Preoperative increased serum periostin and eosinophils in NPs are associated with the preventive effect of ESS for asthma exacerbations in CRS patients comorbid with asthma.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 30, 2020 Category: Allergy & Immunology Source Type: research

Charcot-Leyden Crystal Protein in Nasal Secretions of Patients with Nonallergic Rhinitis with Eosinophilia Syndrome
Conclusions: CLC protein levels are significantly higher in nasal secretions of NARES patients and associated with the degree of nasal eosinophilia and the severity of nasal symptoms. Significantly, nasal secretion CLC protein levels obviously decreased after treatment with intranasal corticosteroids, suggesting its possible role in evaluating the medical treatment.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 21, 2020 Category: Allergy & Immunology Source Type: research

Higher Eosinophils Predict Death-Censored Technique Failure in Peritoneal Dialysis Patients
Conclusion: EOC was increased significantly after PD initiation, and increased numbers of eosinophils were associated with higher death-censored technique failure in PD patients, especially women.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 21, 2020 Category: Allergy & Immunology Source Type: research

Pathogenesis and Therapy of Primary Cutaneous T-Cell Lymphoma: Collegium Internationale Allergologicum (CIA) Update 2020
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous disease group of unknown etiology with a complex immunological background. As CTCL arises from T cells that have a vital role in the antitumor response, their therapy is largely aimed at reversing the immunological mechanisms leading to or manifesting during this malignancy. Early disease stages can be controlled with skin-directed therapy in most CTCL cases. Still, advanced CTCL has a dismal prognosis and warrants systemic therapy. Despite considerable progress in understanding the pathophysiology of the disease and the numerous systemic treatment options available, long...
Source: International Archives of Allergy and Immunology - July 20, 2020 Category: Allergy & Immunology Source Type: research

Predictive and Diagnostic Value of Nasal Nitric Oxide in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps
Conclusion: Measurement of nNO is useful for the early diagnosis of eCRSwNP.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 20, 2020 Category: Allergy & Immunology Source Type: research

Erratum
Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 17, 2020 Category: Allergy & Immunology Source Type: research

Primary Ciliary Dyskinesia: The Impact of Taste Receptor ( < b > < i > TAS2R38 < /i > < /b > ) Gene Polymorphisms on Disease Outcome and Severity
Conclusions: Here, we report, for the first time, a possible association ofTAS2R38 polymorphisms with PCD phenotype.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 13, 2020 Category: Allergy & Immunology Source Type: research

Roles of Thyroid Hormones, Mast Cells, and Inflammatory Mediators in the Initiation and Progression of Autoimmune Thyroid Diseases
Conclusions: When exposed to excessive amounts of thyroid hormones, an inflammatory response is triggered in the thyroid gland, and mast cells overexpress costimulating CD86 in the thyroid. This finding confirms their possible involvement in auto ­antigen presentation. Significant increase in the levels of interferon-γ shows a determining influence of cytokine on the progression of the pathological process.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 8, 2020 Category: Allergy & Immunology Source Type: research

Analysis of Innate and Adaptive Immunological Characteristics in Patients with IgG4-Related Disease
Conclusion: These findings showed that IgG4-RD is related to the increment of CD14+ monocytes. Besides, controlling increased TGF- β-producing CD14+ monocytes with RTX treatment might be a conducive way to regulate IgG4-RD.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 6, 2020 Category: Allergy & Immunology Source Type: research