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Infectious Disease: Aspergillus

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Total 481 results found since Jan 2013.

Does Spore Count Matter in Fungal Allergy?: The Role of Allergenic Fungal Species.
CONCLUSIONS: The major factor causing exacerbation of allergic symptoms in established fungal allergic patients may be the spore concentration of specific allergenic fungi rather than the total fungal concentration. These results may be useful in making recommendations as regards environmental control for fungal allergic patients. PMID: 27334778 [PubMed]
Source: Allergy, Asthma and Immunology Research - June 24, 2016 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
ConclusionsSPT solutions are sensitive and essential diagnostic tools for the detection of mould sensitization. Our recommendation for diagnosis would be to test at least Alt a, Asp f and Pen ch using SPT and additional sIgE test to mx1.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - March 29, 2016 Category: Allergy & Immunology Authors: S. Kespohl, S. Maryska, J. Bünger, O. Hagemeyer, T. Jakob, M. Joest, R. Knecht, D. Koschel, N. Kotschy‐Lang, R. Merget, N.K. Mülleneisen, U. Rabe, S. Röseler, I. Sander, D. Stollewerk, H. Straube, H.M. Ulmer, V. van Kampen, J. Walusiak‐Skorupa, M. Tags: Original Article ‐Clinical Allergy Source Type: research

Allergy testing in asthmatics and severe asthmatics: habits among respiratory physicians in Belgium
Conclusions: There is a large heterogeneity among Belgian respiratory physicians regarding decision making in allergy testing in patients with asthma.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Flahou, B., Van Schoor, J., Vancayzeele, S., Gurdain, S. Tags: Allergy and immunology Source Type: research

Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma.
CONCLUSION: The absence of atopic eczema and allergic rhinitis in these patients increases the likelihood of ABPA. Eliciting an accurate allergy history may be a useful bedside clinical tool when considering the diagnosis of ABPA. PMID: 27234940 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 23, 2016 Category: Allergy & Immunology Authors: Tay TR, Bosco J, Gillman A, Aumann H, Stirling R, O'Hehir R, Hew M Tags: Ann Allergy Asthma Immunol Source Type: research

Asthma & Allergy Development: Contrasting Influences of Yeasts & Other Fungal Exposures
Conclusions and Clinical RelevanceDespite the irritant and allergenic properties of fungi, early‐life elevated dust yeast exposures or their components may be protective against allergy and asthma in children at risk for these outcomes. Ascertainment of fungal components associated with immunoprotective effects may have therapeutic relevance for asthma.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - September 1, 2014 Category: Allergy & Immunology Authors: Behrooz Behbod, Joanne E. Sordillo, Elaine B. Hoffman, Soma Datta, Tara E. Webb, Doris L. Kwan, Jimmy A. Kamel, Michael L. Muilenberg, James A. Scott, Ginger L. Chew, Thomas A.E. Platts‐Mills, Joel Schwartz, Brent Coull, Harriet Burge, Diane R. Gold Tags: Original Article‐Epidemiology of Allergic Disease Source Type: research

Asthma and allergy development: contrasting influences of yeasts and other fungal exposures
Conclusions and Clinical RelevanceDespite the irritant and allergenic properties of fungi, early‐life elevated dust yeast exposures or their components may be protective against allergy and asthma in children at risk for these outcomes. Ascertainment of fungal components associated with immunoprotective effects may have therapeutic relevance for asthma.
Source: Clinical and Experimental Allergy - December 26, 2014 Category: Allergy & Immunology Authors: B. Behbod, J. E. Sordillo, E. B. Hoffman, S. Datta, T. E. Webb, D. L. Kwan, J. A. Kamel, M. L. Muilenberg, J. A. Scott, G. L. Chew, T. A. E. Platts‐Mills, J. Schwartz, B. Coull, H. Burge, D. R. Gold Tags: Original Article Source Type: research

Clinical peculiarities of seasonal respiratory allergy in children
Conclusion: Presence of mold hypersensitivity in children determines more severe nasal and bronchial symptoms, lower asthma control and prolonged exacerbation (p<0,05).
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Kuznietsova, O., Nedelska, S. Tags: Allergy and immunology Source Type: research

A comparison of subject room dust with home vacuum dust for evaluation of dust-borne aeroallergens.
CONCLUSION: Allergens and antigens tested from samples collected by protocol and by grab sampling from the home vacuum were highly positively correlated. Grab samples taken from the family vacuum may be a good surrogate for evaluating home allergen exposure. PMID: 23622010 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - May 1, 2013 Category: Allergy & Immunology Authors: Barnes C, Portnoy JM, Ciaccio CE, Pacheco F Tags: Ann Allergy Asthma Immunol Source Type: research

A novel model of invasive fungal rhinosinusitis in rats.
CONCLUSION: A rat IFRS model was successfully developed through nasal obstruction, CPA-induced neutropenia, and fungal inoculation. The disease modelclosely mimics the pathophysiology of anthropic IFRS. PMID: 23816783 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - June 21, 2013 Category: ENT & OMF Authors: Zhang F, An Y, Li Z, Zhao C Tags: Am J Rhinol Allergy Source Type: research

Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.
CONCLUSION: Multiple fungal species can colonize the airway, and dissociation between colonizing and sensitizing species frequently occurs in definitive ABPA. Considering the increased prevalence of azole-resistant Aspergillus spp., administering antifungal drugs that target A. fumigatus without identifying which fungal species colonize the airway might be problematic. PMID: 23987194 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 1, 2013 Category: Allergy & Immunology Authors: Matsuse H, Tsuchida T, Fukahori S, Kawano T, Nishino T, Fukushima C, Kohno S Tags: Ann Allergy Asthma Immunol Source Type: research

Effects of fungi and eosinophils on mucin gene expression in rhinovirus-infected nasal epithelial cells.
CONCLUSIONS: RV-16, airborne fungi, and eosinophils may exacerbate the inflammatory process in nasal mucosal diseases by enhancing mucin gene expression. PMID: 24587952 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Measurement of aeroallergens from furnace filters.
CONCLUSION: Allergens from 5 common aeroallergen species and antigenic material from 4 common fungal taxa can be measured in dust taken from high-efficiency furnace filters. PMID: 25457862 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - November 18, 2014 Category: Allergy & Immunology Authors: Barnes CS, Allenbrand R, Mohammed M, Gard L, Pacheco F, Kennedy K, Portnoy JM, Ciaccio C Tags: Ann Allergy Asthma Immunol Source Type: research

Development of Aspergillus protease with ovalbumin-induced allergic chronic rhinosinusitis model in the mouse.
CONCLUSION: Aspergillus protease combined with OVA induced more severe allergic inflammation in sinonasal mucosa compared with OVA alone and similar eosinophilia. This model could be more relevant to recalcitrant eosinophilic CRS in humans than OVA-induced allergic CRS. PMID: 25514482 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2014 Category: ENT & OMF Authors: Kim JH, Yi JS, Gong CH, Jang YJ Tags: Am J Rhinol Allergy Source Type: research

Mixing compatibilities of Aspergillus and American cockroach allergens with other high-protease fungal and insect extracts.
CONCLUSION: Aspergillus extracts exhibited favorable stabilities after mixing with other high-protease products. American cockroach extract potencies were unstable in less than 50% glycerin, even in the absence of other protease-containing allergens, and were destabilized in mixtures with several fungal extracts. Addition of fungal and insect extracts to separate treatment vials or preparation of fungal-insect mixtures at elevated glycerin concentrations might be necessary to produce compatible patient formulations for allergen immunotherapy injections. PMID: 25578248 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 8, 2015 Category: Allergy & Immunology Authors: Grier TJ, Hall DM, Duncan EA, Coyne TC Tags: Ann Allergy Asthma Immunol Source Type: research

Prognostic factors for survival in patients with acute invasive fungal rhinosinusitis.
CONCLUSIONS: Overall survival rate remained approximately 50% in patients with AIFR. The prognosis of AIFR is significantly influenced by underlying diseases, accompanying neutropenia, CRP levels, symptom duration, involvement of septum, and the presence of facial swelling. Elevation of CRP, in particular, was an independent predictor of poor outcomes and should be monitored appropriately. PMID: 25590320 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2015 Category: ENT & OMF Authors: Cho HJ, Jang MS, Hong SD, Chung SK, Kim HY, Dhong HJ Tags: Am J Rhinol Allergy Source Type: research