Long-term pollen trends and associations between pollen phenology and seasonal climate in Atlanta, Georgia (1992-2018)
CONCLUSION: Allergenic pollen concentrations for several types of pollen are increasing and trending toward an earlier pollen release in Atlanta, GA. Warmer temperatures preceding the pollen season were associated with the earlier pollen release.PMID:34311074 | DOI:10.1016/j.anai.2021.07.012 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 26, 2021 Category: Allergy & Immunology Authors: Arie Manangan Claudia Brown Shubhayu Saha Jesse Bell Jeremy Hess Chris Uejio Stanley Fineman Paul Schramm Source Type: research

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This book provides a comprehensive review of the aerosol technology literature by separating the text into 3 separate sections. The first section evaluates the physiology of aerosol therapy, with 7 chapters dedicated to the following topics: (1) physiochemical properties of respiratory particles and formulations, (2) particle deposition in the respiratory tract and the effect of respiratory disease, (3) bioavailability of inhaled compounds, and (4) an overview of the delivery technologies of inhalation aerosols. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 26, 2021 Category: Allergy & Immunology Authors: John J. Oppenheimer Tags: Book Review Source Type: research

How Good Are Mast Cell Mediators?
Ann Allergy Asthma Immunol. 2021 Jul 22:S1081-1206(21)00515-9. doi: 10.1016/j.anai.2021.07.016. Online ahead of print.NO ABSTRACTPMID:34303837 | DOI:10.1016/j.anai.2021.07.016 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 25, 2021 Category: Allergy & Immunology Authors: Catherine R Weiler Source Type: research

How Good Are Mast Cell Mediators?
Ann Allergy Asthma Immunol. 2021 Jul 22:S1081-1206(21)00515-9. doi: 10.1016/j.anai.2021.07.016. Online ahead of print.NO ABSTRACTPMID:34303837 | DOI:10.1016/j.anai.2021.07.016 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 25, 2021 Category: Allergy & Immunology Authors: Catherine R Weiler Source Type: research

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The seventh edition of Medical Immunology provides a concise narrative regarding clinically relevant topics in immunology. This text is a useful resource for those who desire a broad overview of clinically relevant aspects of the immune system and can be utilized as a concise, high-yield review of basic, diagnostic, and clinical immunology. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 25, 2021 Category: Allergy & Immunology Authors: Christopher Brooks, Kelsey Lecerf Tags: Book Review Source Type: research

Annato hypersensitivity after oral ingestion confirmed by placebo-controlled, oral challenge.
Natural dyes, in contrast to synthetic ones, can be a source of protein, so their consumption may be associated with IgE-dependent allergic reactions. Among natural dyes, symptoms were most often observed after carmine ingestion1 and only occasionally after annatto and concerned the skin, respiratory system or even anaphylaxis. Annato (E-160b) is a natural yellow-orange dye obtained from the seeds of the tropical tree Bixa orenella, coming from Americas.2 It is found as a colorant in many foods, such as cheese, margarine, breakfast cereals, grilled chicken, dressings, coffee creamers, mustard, colored rice, popcorn, ice cr...
Source: Annals of Allergy, Asthma and Immunology - July 25, 2021 Category: Allergy & Immunology Authors: Beata Sadowska, Marlena Sztormowska, Marta Che łmińska Tags: Letters Source Type: research

Sex differences in antibody responses to the 23-valent pneumococcal polysaccharide vaccination
Ann Allergy Asthma Immunol. 2021 Jul 20:S1081-1206(21)00512-3. doi: 10.1016/j.anai.2021.07.013. Online ahead of print.NO ABSTRACTPMID:34298171 | DOI:10.1016/j.anai.2021.07.013 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Sergio E Chiarella Sarah M Jenkins Miguel A Park Roshini S Abraham Avni Y Joshi Source Type: research

Pathogenic and diagnostic relevance of kit in primary mast cell activation disorders
CONCLUSION: The clinical heterogeneity and complexity of the molecular assays needed for the study of MCAS patients might lead to misdiagnosis, particularly when patients are evaluated at non-specialized centers. Thus, referral of patients suffering from clinical manifestations suggestive of MCAS to Reference Centers on mastocytosis and MC diseases is strongly recommended.PMID:34298172 | DOI:10.1016/j.anai.2021.07.014 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Javier I Mu ñoz-González Andr és C García-Montero Alberto Orfao Iv án Álvarez-Twose Source Type: research

Demographic and clinical characteristics of patients with hereditary angioedema in Canada
CONCLUSION: Canadian patients with HAE share common clinical characteristics with HAE patients in other countries. They showed a delay in HAE diagnosis and a high burden of disease as indicated by the high frequency of attacks in the preceding 6 months. This study provides a better understanding of the demographic and clinical characteristics Canadian patients with HAE.PMID:34298173 | DOI:10.1016/j.anai.2021.07.015 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Erika Yue Lee Jane Hsieh Teresa Caballero Christine McCusker Amin Kanani Gina Lacuesta Rozita Borici-Mazi Susan Waserman Stephen Betschel Source Type: research

Sex differences in antibody responses to the 23-valent pneumococcal polysaccharide vaccination
Ann Allergy Asthma Immunol. 2021 Jul 20:S1081-1206(21)00512-3. doi: 10.1016/j.anai.2021.07.013. Online ahead of print.NO ABSTRACTPMID:34298171 | DOI:10.1016/j.anai.2021.07.013 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Sergio E Chiarella Sarah M Jenkins Miguel A Park Roshini S Abraham Avni Y Joshi Source Type: research

Pathogenic and diagnostic relevance of kit in primary mast cell activation disorders
CONCLUSION: The clinical heterogeneity and complexity of the molecular assays needed for the study of MCAS patients might lead to misdiagnosis, particularly when patients are evaluated at non-specialized centers. Thus, referral of patients suffering from clinical manifestations suggestive of MCAS to Reference Centers on mastocytosis and MC diseases is strongly recommended.PMID:34298172 | DOI:10.1016/j.anai.2021.07.014 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Javier I Mu ñoz-González Andr és C García-Montero Alberto Orfao Iv án Álvarez-Twose Source Type: research

Demographic and clinical characteristics of patients with hereditary angioedema in Canada
CONCLUSION: Canadian patients with HAE share common clinical characteristics with HAE patients in other countries. They showed a delay in HAE diagnosis and a high burden of disease as indicated by the high frequency of attacks in the preceding 6 months. This study provides a better understanding of the demographic and clinical characteristics Canadian patients with HAE.PMID:34298173 | DOI:10.1016/j.anai.2021.07.015 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Erika Yue Lee Jane Hsieh Teresa Caballero Christine McCusker Amin Kanani Gina Lacuesta Rozita Borici-Mazi Susan Waserman Stephen Betschel Source Type: research

Long-term pollen trends and associations between pollen phenology and seasonal climate in Atlanta, Georgia (1992-2018)
Previous research has shown airborne pollen concentrations and phenology in allergenic plants are changing. Additionally, variations in seasonal climate are known to affect pollen phenology in trees, weeds, and grasses. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Arie Manangan, Claudia Brown, Shubhayu Saha, Jesse Bell, Jeremy Hess, Chris Uejio, Stanley Fineman, Paul Schramm Tags: Original Article Source Type: research

How Good Are Mast Cell Mediators?
Mast cells (MCs) are an integral part of the immune system. They play a pivotal role in several allergic and other immune responses. MCs store several mediators in their granules and synthesize new mediators which facilitate their function. The levels of some of those mediators and/or their metabolites are used for the diagnosis of MC activation and MC disorders.1 However, recent data regarding some of those mediators need to be addressed and incorporated into the diagnostic criteria of MC activation and disorders. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 22, 2021 Category: Allergy & Immunology Authors: Catherine R Weiler Tags: Perspective Source Type: research

Sex differences in antibody responses to the 23-valent pneumococcal polysaccharide vaccination
There are profound sex-based differences in both humoral and cellular immune responses to vaccination [1]. In general, adult females demonstrate higher antibody responses to bacterial and viral vaccines than men [2]. For instance, adult females vaccinated with half the dose of the trivalent inactivated influenza vaccine (TIV) produce similar humoral immune responses than adult males vaccinated with a full dose of the TIV [3]. Given that the 23-valent pneumococcal polysaccharide vaccine (PPSV23) is an important tool in our evaluation of the humoral immune response [4], we sought to determine if men and women have a signific...
Source: Annals of Allergy, Asthma and Immunology - July 19, 2021 Category: Allergy & Immunology Authors: Sergio E. Chiarella, Sarah M. Jenkins, Miguel A. Park, Roshini S. Abraham, Avni Y. Joshi Tags: Letters Source Type: research

Pathogenic and diagnostic relevance of kit in primary mast cell activation disorders
Mast cell (MC) activation (MCA) defines the mechanism by which certain patients suffer from symptoms due to the effect of a wide range of mediators released from MC upon their activation triggered by different stimuli. When these symptoms are severe and recurrent, the diagnosis of MCA syndrome (MCAS) might be considered. Here we review the relevant aspects related to the pathogenesis of MCAS, with special emphasis on the prevalence and diagnostic relevance of KIT mutations. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 19, 2021 Category: Allergy & Immunology Authors: Javier I. Mu ñoz-González, Andrés C. García-Montero, Alberto Orfao, Iván Álvarez-Twose Tags: Review Source Type: research

Demographic and clinical characteristics of patients with hereditary angioedema in Canada
Data on the clinical and demographic features of Canadian patients with hereditary angioedema (HAE) is lacking. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 19, 2021 Category: Allergy & Immunology Authors: Erika Yue Lee, Jane Hsieh, Teresa Caballero, Christine McCusker, Amin Kanani, Gina Lacuesta, Rozita Borici-Mazi, Susan Waserman, Stephen Betschel Tags: Original Article Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00500-7. doi: 10.1016/j.anai.2021.07.009. Online ahead of print.NO ABSTRACTPMID:34273483 | DOI:10.1016/j.anai.2021.07.009 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Minh H N Nguyen Melissa Baker Tahnee Spoden Maritza Gisel Rivera-Valenzuela Roua Azmeh Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00502-0. doi: 10.1016/j.anai.2021.07.011. Online ahead of print.NO ABSTRACTPMID:34273484 | DOI:10.1016/j.anai.2021.07.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Laurel Ball Stephanie A Velasquez Omar M Al Jammal Andrew A White Praveen Akuthota Source Type: research

Exacerbations in US Severe Asthma: Incidence, Characteristics, Predictors, and Effects of Biologic Treatments
CONCLUSION: In this real-world cohort of specialist-treated US adults with SA, there was a substantial burden of exacerbations and associated healthcare resource utilization. Patients receiving biologics had a lower exacerbation burden.PMID:34273485 | DOI:10.1016/j.anai.2021.07.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Jennifer Trevor Njira Lugogo Warner Carr Wendy C Moore Weily Soong Reynold A Panettieri Pooja Desai Frank Trudo Christopher S Ambrose Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00500-7. doi: 10.1016/j.anai.2021.07.009. Online ahead of print.NO ABSTRACTPMID:34273483 | DOI:10.1016/j.anai.2021.07.009 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Minh H N Nguyen Melissa Baker Tahnee Spoden Maritza Gisel Rivera-Valenzuela Roua Azmeh Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00502-0. doi: 10.1016/j.anai.2021.07.011. Online ahead of print.NO ABSTRACTPMID:34273484 | DOI:10.1016/j.anai.2021.07.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Laurel Ball Stephanie A Velasquez Omar M Al Jammal Andrew A White Praveen Akuthota Source Type: research

Exacerbations in US Severe Asthma: Incidence, Characteristics, Predictors, and Effects of Biologic Treatments
CONCLUSION: In this real-world cohort of specialist-treated US adults with SA, there was a substantial burden of exacerbations and associated healthcare resource utilization. Patients receiving biologics had a lower exacerbation burden.PMID:34273485 | DOI:10.1016/j.anai.2021.07.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Jennifer Trevor Njira Lugogo Warner Carr Wendy C Moore Weily Soong Reynold A Panettieri Pooja Desai Frank Trudo Christopher S Ambrose Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00500-7. doi: 10.1016/j.anai.2021.07.009. Online ahead of print.NO ABSTRACTPMID:34273483 | DOI:10.1016/j.anai.2021.07.009 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Minh H N Nguyen Melissa Baker Tahnee Spoden Maritza Gisel Rivera-Valenzuela Roua Azmeh Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00502-0. doi: 10.1016/j.anai.2021.07.011. Online ahead of print.NO ABSTRACTPMID:34273484 | DOI:10.1016/j.anai.2021.07.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Laurel Ball Stephanie A Velasquez Omar M Al Jammal Andrew A White Praveen Akuthota Source Type: research

Exacerbations in US Severe Asthma: Incidence, Characteristics, Predictors, and Effects of Biologic Treatments
CONCLUSION: In this real-world cohort of specialist-treated US adults with SA, there was a substantial burden of exacerbations and associated healthcare resource utilization. Patients receiving biologics had a lower exacerbation burden.PMID:34273485 | DOI:10.1016/j.anai.2021.07.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Jennifer Trevor Njira Lugogo Warner Carr Wendy C Moore Weily Soong Reynold A Panettieri Pooja Desai Frank Trudo Christopher S Ambrose Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00500-7. doi: 10.1016/j.anai.2021.07.009. Online ahead of print.NO ABSTRACTPMID:34273483 | DOI:10.1016/j.anai.2021.07.009 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Minh H N Nguyen Melissa Baker Tahnee Spoden Maritza Gisel Rivera-Valenzuela Roua Azmeh Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00502-0. doi: 10.1016/j.anai.2021.07.011. Online ahead of print.NO ABSTRACTPMID:34273484 | DOI:10.1016/j.anai.2021.07.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Laurel Ball Stephanie A Velasquez Omar M Al Jammal Andrew A White Praveen Akuthota Source Type: research

Exacerbations in US Severe Asthma: Incidence, Characteristics, Predictors, and Effects of Biologic Treatments
CONCLUSION: In this real-world cohort of specialist-treated US adults with SA, there was a substantial burden of exacerbations and associated healthcare resource utilization. Patients receiving biologics had a lower exacerbation burden.PMID:34273485 | DOI:10.1016/j.anai.2021.07.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Jennifer Trevor Njira Lugogo Warner Carr Wendy C Moore Weily Soong Reynold A Panettieri Pooja Desai Frank Trudo Christopher S Ambrose Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00500-7. doi: 10.1016/j.anai.2021.07.009. Online ahead of print.NO ABSTRACTPMID:34273483 | DOI:10.1016/j.anai.2021.07.009 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Minh H N Nguyen Melissa Baker Tahnee Spoden Maritza Gisel Rivera-Valenzuela Roua Azmeh Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Ann Allergy Asthma Immunol. 2021 Jul 14:S1081-1206(21)00502-0. doi: 10.1016/j.anai.2021.07.011. Online ahead of print.NO ABSTRACTPMID:34273484 | DOI:10.1016/j.anai.2021.07.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Laurel Ball Stephanie A Velasquez Omar M Al Jammal Andrew A White Praveen Akuthota Source Type: research

Exacerbations in US Severe Asthma: Incidence, Characteristics, Predictors, and Effects of Biologic Treatments
CONCLUSION: In this real-world cohort of specialist-treated US adults with SA, there was a substantial burden of exacerbations and associated healthcare resource utilization. Patients receiving biologics had a lower exacerbation burden.PMID:34273485 | DOI:10.1016/j.anai.2021.07.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2021 Category: Allergy & Immunology Authors: Jennifer Trevor Njira Lugogo Warner Carr Wendy C Moore Weily Soong Reynold A Panettieri Pooja Desai Frank Trudo Christopher S Ambrose Source Type: research

Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision rule
Ann Allergy Asthma Immunol. 2021 Jul 13:S1081-1206(21)00496-8. doi: 10.1016/j.anai.2021.07.005. Online ahead of print.ABSTRACTBACKGROUND: Challenge of delabeling amoxicillin allergy is a significant issue for patients and clinicians, especially when anaphylaxis is reported. A recent study has proposed a clinical decision rule, PEN-FAST, to identify low-risk penicillin allergies.OBJECTIVE: We sought TO: validate the PEN-FAST clinical decision rule in a population with high risk of suspected immediate amoxicillin allergy and to identify clinical predictive factors of amoxicillin immediate hypersensitivity.METHODS: We RETROSP...
Source: Annals of Allergy, Asthma and Immunology - July 16, 2021 Category: Allergy & Immunology Authors: Anays Piotin Julien GodetPhD Jason A Trubiano Manon Grandbastien Lydie Guenard Fr édéric de Blay Carine Metz Favre Source Type: research

Symptoms of Mast Cell Activation: The Patient Perspective
Ann Allergy Asthma Immunol. 2021 Jul 13:S1081-1206(21)00494-4. doi: 10.1016/j.anai.2021.07.004. Online ahead of print.NO ABSTRACTPMID:34271184 | DOI:10.1016/j.anai.2021.07.004 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 16, 2021 Category: Allergy & Immunology Authors: Susan V Jennings Valerie M Slee Celeste C Finnerty Jan B Hempstead Angela S Bowman Source Type: research

Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision rule
Ann Allergy Asthma Immunol. 2021 Jul 13:S1081-1206(21)00496-8. doi: 10.1016/j.anai.2021.07.005. Online ahead of print.ABSTRACTBACKGROUND: Challenge of delabeling amoxicillin allergy is a significant issue for patients and clinicians, especially when anaphylaxis is reported. A recent study has proposed a clinical decision rule, PEN-FAST, to identify low-risk penicillin allergies.OBJECTIVE: We sought TO: validate the PEN-FAST clinical decision rule in a population with high risk of suspected immediate amoxicillin allergy and to identify clinical predictive factors of amoxicillin immediate hypersensitivity.METHODS: We RETROSP...
Source: Annals of Allergy, Asthma and Immunology - July 16, 2021 Category: Allergy & Immunology Authors: Anays Piotin Julien GodetPhD Jason A Trubiano Manon Grandbastien Lydie Guenard Fr édéric de Blay Carine Metz Favre Source Type: research

Symptoms of Mast Cell Activation: The Patient Perspective
Ann Allergy Asthma Immunol. 2021 Jul 13:S1081-1206(21)00494-4. doi: 10.1016/j.anai.2021.07.004. Online ahead of print.NO ABSTRACTPMID:34271184 | DOI:10.1016/j.anai.2021.07.004 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 16, 2021 Category: Allergy & Immunology Authors: Susan V Jennings Valerie M Slee Celeste C Finnerty Jan B Hempstead Angela S Bowman Source Type: research

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This is a well-organized and well-written book. The case-based format is very helpful in relaying practical information regarding evaluation, diagnosis, and management of immune deficiency in patients. The laboratory evaluation and differential diagnoses are discussed for each case, and a detailed overview of the specific immune defect is discussed to help the reader integrate basic immunology with the clinical presentation of patients. Finally, the management of the immune deficiency is discussed for each case. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 16, 2021 Category: Allergy & Immunology Authors: Anne B. Yates Tags: Book Review Source Type: research

Should Asthmatic Children Simply be Treated as Little Adults?
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00498-1. doi: 10.1016/j.anai.2021.07.007. Online ahead of print.NO ABSTRACTPMID:34260900 | DOI:10.1016/j.anai.2021.07.007 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Mfonobong Udoko Heather De Keyser Stanley J Szefler For Annals of Allergy, Asthma and Immunology Source Type: research

Inadequate literacy is associated with uncontrolled asthma in adolescents
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00493-2. doi: 10.1016/j.anai.2021.07.003. Online ahead of print.NO ABSTRACTPMID:34260901 | DOI:10.1016/j.anai.2021.07.003 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Amelia Licari Riccardo Castagnoli Riccardo Ciprandi Gian Luigi Marseglia Giorgio Ciprandi Source Type: research

Anaphylaxis-related knowledge and concerns in Canadian families during COVID-19
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00495-6. doi: 10.1016/j.anai.2021.07.006. Online ahead of print.NO ABSTRACTPMID:34260902 | DOI:10.1016/j.anai.2021.07.006 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Sofianne Gabrielli Jennifer Lp Protudjer Gregory Gooding Jennifer Gerdts Moshe Ben-Shoshan Source Type: research

Should Asthmatic Children Simply be Treated as Little Adults?
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00498-1. doi: 10.1016/j.anai.2021.07.007. Online ahead of print.NO ABSTRACTPMID:34260900 | DOI:10.1016/j.anai.2021.07.007 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Mfonobong Udoko Heather De Keyser Stanley J Szefler For Annals of Allergy, Asthma and Immunology Source Type: research

Inadequate literacy is associated with uncontrolled asthma in adolescents
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00493-2. doi: 10.1016/j.anai.2021.07.003. Online ahead of print.NO ABSTRACTPMID:34260901 | DOI:10.1016/j.anai.2021.07.003 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Amelia Licari Riccardo Castagnoli Riccardo Ciprandi Gian Luigi Marseglia Giorgio Ciprandi Source Type: research

Anaphylaxis-related knowledge and concerns in Canadian families during COVID-19
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00495-6. doi: 10.1016/j.anai.2021.07.006. Online ahead of print.NO ABSTRACTPMID:34260902 | DOI:10.1016/j.anai.2021.07.006 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Sofianne Gabrielli Jennifer Lp Protudjer Gregory Gooding Jennifer Gerdts Moshe Ben-Shoshan Source Type: research

Should Asthmatic Children Simply be Treated as Little Adults?
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00498-1. doi: 10.1016/j.anai.2021.07.007. Online ahead of print.NO ABSTRACTPMID:34260900 | DOI:10.1016/j.anai.2021.07.007 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Mfonobong Udoko Heather De Keyser Stanley J Szefler For Annals of Allergy, Asthma and Immunology Source Type: research

Inadequate literacy is associated with uncontrolled asthma in adolescents
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00493-2. doi: 10.1016/j.anai.2021.07.003. Online ahead of print.NO ABSTRACTPMID:34260901 | DOI:10.1016/j.anai.2021.07.003 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Amelia Licari Riccardo Castagnoli Riccardo Ciprandi Gian Luigi Marseglia Giorgio Ciprandi Source Type: research

Anaphylaxis-related knowledge and concerns in Canadian families during COVID-19
Ann Allergy Asthma Immunol. 2021 Jul 11:S1081-1206(21)00495-6. doi: 10.1016/j.anai.2021.07.006. Online ahead of print.NO ABSTRACTPMID:34260902 | DOI:10.1016/j.anai.2021.07.006 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Sofianne Gabrielli Jennifer Lp Protudjer Gregory Gooding Jennifer Gerdts Moshe Ben-Shoshan Source Type: research

Hemophagocytic lymphohistiocytosis in adult and pediatric patients
Hemophagocytic lymphohistiocytosis (HLH) describes a group of syndromes associated with immune system overstimulation.1 These syndromes can be divided into primary or familial and secondary or reactive.1 Primary HLH results from genetic mutations, whereas secondary HLH is attributed to viral infection, malignancy, or autoimmune condition.1 Diagnosis and management is based on HLH-2004, the most widely used diagnostic criteria of HLH.2 Our study reviews adult and pediatric patients with HLH at our institution to improve the current understanding of this condition. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Minh H.N. Nguyen, Melissa Baker, Tahnee Spoden, Maritza Gisel Rivera-Valenzuela, Roua Azmeh Tags: Letters Source Type: research

Atypical eosinophilic granulomatosis with polyangiitis with spontaneous aspirin reactivity and immunoglobulin E –mediated anaphylaxis
Eosinophilic granulomatosis with polyangiitis (EGPA) and aspirin-exacerbated respiratory disease (AERD) share overlapping pathophysiology characterized by peripheral eosinophilia, nasal polyps, and asthma.1,2 The overlapping nature of the symptoms and etiologies of these 2 diseases emerged recently in a series of case reports reporting additional potential comorbidities.3,4 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Laurel L. Ball, Stephanie A. Velasquez, Omar M. Al Jammal, Andrew A. White, Praveen Akuthota Tags: Letters Source Type: research

Atypical Eosinophilic Granulomatosis with Polyangiitis with Spontaneous Aspirin Reactivity and IgE Mediated Anaphylaxis
Dr. White sits on an advisory board for GSK, Optinose, and Regeneron, is part of a Speaker's Bureau for Optinose, Regeneron/Sanofi, Astra-Zeneca and provides research support for Astra-Zeneca. Otherwise, the authors declare no conflicts of interest (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Laurel Ball, Stephanie A Velasquez, Omar M Al Jammal, Andrew A White, Praveen Akuthota Source Type: research

Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Hemophagocytic lymphohistiocytosis (HLH) describes a group of syndromes associated with immune system overstimulation.1 These syndromes can be divided into primary/familial and secondary/reactive.1 Primary HLH results from genetic mutations, while secondary HLH is attributed to viral infection, malignancy or autoimmune condition.1 Diagnosis and management is based on HLH-2004, the most widely used diagnostic criteria of HLH.2 Our study reviews adult and pediatric patients with HLH at our institution to improve understanding of this condition. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 14, 2021 Category: Allergy & Immunology Authors: Minh H.N. Nguyen, Melissa Baker, Tahnee Spoden, Maritza Gisel Rivera-Valenzuela, Roua Azmeh Source Type: research