Annals of Allergy, Asthma and Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Levels of Immunoglobulin E Sensitization Drive Symptom Thresholds in Allergic Rhinitis
Allergic rhinitis (AR) is a common respiratory disease encompassing a variety of phenotypes. Patients can be sensitized to one or more allergens. There are indications that polysensitization is associated with more severe disease. However, the extent to which the level of sensitization is associated to clinical disease variability, underlying the distinct nature of AR from AR+ conjunctivitis or AR+ asthma, is not known. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 26, 2024 Category: Allergy & Immunology Authors: Maria V. Dimou, Paraskevi Xepapadaki, John Lakoumentas, Leonardos Mageiros, Xenophon Aggelidis, Maria Antonopoulou, Petros Bakakos, Sophia Βotskariova, Konstantinos Chliveros, Spyridon Chrysoulakis, Dionysios Dimas, Nikolaos Douladiris, Mina Gaga, Christ Tags: Original Article Source Type: research

The Future of Therapeutic Options for Hereditary Angioedema
Hereditary angioedema (HAE) is a rare, genetic condition causing unpredictable and severe episodes of angioedema that are debilitating and life-threatening. HAE can be classified into HAE due to C1INH deficiency (HAE-C1INH), or HAE with normal C1INH (HAE-nl-C1INH). HAE-C1INH is subcategorized as type I and II based upon deficient or dysfunctional circulating C1INH protein resulting from inherited or spontaneous mutations in the SERPING1 gene leading to uncontrolled Factor XII(FXII)/plasma kallikrein activation and excessive bradykinin production. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 26, 2024 Category: Allergy & Immunology Authors: Tukisa D. Smith, Marc A. Riedl Tags: Review Source Type: research

Cow's milk oral immunotherapy has differentially better long-term adherence than peanut or sesame
IgE-mediated food allergy is a global health problem.1,2 In recent years, several scientific societies have endorsed the use of off-the-shelf foods in clinical oral immunotherapy (OIT) practice.3 –5 Moreover, manufactured well-standardized peanut allergens have also been used.6 Our study aimed to evaluate and compare adherence to and safety of OIT in patients with different food allergens at the maintenance dose (MD) phase in a single center. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Meital Almog, Nadira Musallam, Roni Wagner, Larisa Epov, Lisa Kaly, Vika Dor, Aharon Kessel Tags: Letters Source Type: research

IgE deficiency is not associated with hypogammaglobulinemia in a large cohort of military recruits
IgE deficiency (IgED) (IgE (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Thomas Makin, Larry Borish, Cade M. Nylund, Jeffrey M. Wilson, Monica G. Lawrence Tags: Letters Source Type: research

Mast cell signaling and its role in urticaria
Chronic urticaria (CU) is a mast cells (MC)-driven disease characterized by the development of itching wheals and/or angioedema. In the last decades, outstanding progress has been made in defining the mechanisms involved in MC activation, and novel activating and inhibitory receptors expressed in MC surface were identified and characterized. Besides an IgE-mediated activation via Fc εRI-cross-linking, other activating receptors, including Mas-related G protein–coupled receptor-X2 (MRGPRX2), C5a receptor and protease-activated receptors (PAR1 and PAR2) are responsible for MC activation. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 23, 2024 Category: Allergy & Immunology Authors: Ilaria Puxeddu, Francesca Pistone, Francesco Pisani, Francesca Levi-Schaffer Tags: Review Source Type: research

Beyond the textbook: the challenges of learning (and teaching) basic immunology in allergy-immunology training programs
For incoming allergy-immunology fellows, learning basic immunology is daunting due to the complexity of the topic and limited exposure during undergraduate medical education. Allergy-immunology exposure is also limited during primary residency training, especially for trainees from programs without an allergy-immunology training program.1 A lack of educational infrastructure for immunology in graduate medical education (GME) results in self-directed learning and inconsistent knowledge in spite of the broad framework provided by certification boards. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 23, 2024 Category: Allergy & Immunology Authors: Andrew White, Rebecca Saff, Rebecca Scherzer, Paneez Khoury Tags: Letters Source Type: research

Sociodemographic factors linked to food allergy diagnosis among high-risk children with atopic dermatitis
CONCLUSION: Labeling at-risk young children with food allergy without thorough objective testing can impact their nutrition and quality of life. Barriers to equitable evaluation of food allergy diagnosis should be further investigated and addressed.PMID:38648973 | DOI:10.1016/j.anai.2024.04.016 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 22, 2024 Category: Allergy & Immunology Authors: Ellen Daily Stephen Sven Wang Manali Shah Anandu Dileep Shannon Manz Niki Mirhosseini Mahboobeh Mahdavinia Source Type: research

Another Link Between Adult Orbital Xanthogranulomatous Disease and IgG4-related disease
Ann Allergy Asthma Immunol. 2024 Apr 20:S1081-1206(24)00235-7. doi: 10.1016/j.anai.2024.04.014. Online ahead of print.NO ABSTRACTPMID:38648974 | DOI:10.1016/j.anai.2024.04.014 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 22, 2024 Category: Allergy & Immunology Authors: Taya Carpenter Catherine Ye Alan Wolff Eugene Capitle Source Type: research

Effects of Extreme Weather on Health in Underserved Communities
Ann Allergy Asthma Immunol. 2024 Apr 20:S1081-1206(24)00237-0. doi: 10.1016/j.anai.2024.04.018. Online ahead of print.ABSTRACTIncreased fossil fuel usage has increased CO2 concentrations leading to global warming and climate change with increased frequency and intensity of extreme weather events such as thunderstorms, wildfires, droughts, heat waves, and others. These changes increase the risk of adverse health effects for all human beings. However, these experiences do not impact everyone equally. Underserved communities, including people of color, the elderly, people living with chronic conditions, and socioeconomically ...
Source: Annals of Allergy, Asthma and Immunology - April 22, 2024 Category: Allergy & Immunology Authors: Sotheany R Leap Derek R Soled Vanitha Sampath Kari C Nadeau Source Type: research

Amikacin SDRIFE on the basis of neomycin cross-reactivity managed with desensitization and treating through
Ann Allergy Asthma Immunol. 2024 Apr 20:S1081-1206(24)00239-4. doi: 10.1016/j.anai.2024.04.017. Online ahead of print.NO ABSTRACTPMID:38648976 | DOI:10.1016/j.anai.2024.04.017 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 22, 2024 Category: Allergy & Immunology Authors: Morgan N Vincent Jordon Jaggers Christina Fiske Elizabeth J Phillips Joanna L Stollings Source Type: research

Evaluating an e-device to monitor the type 2 high unified airway response to dupilumab
Ann Allergy Asthma Immunol. 2024 Apr 19:S1081-1206(24)00233-3. doi: 10.1016/j.anai.2024.04.015. Online ahead of print.NO ABSTRACTPMID:38643948 | DOI:10.1016/j.anai.2024.04.015 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 21, 2024 Category: Allergy & Immunology Authors: Kirsten Stewart Chris RuiWen Kuo Rory Chan Brian Lipworth Source Type: research