Point of care ultrasonography in the allergy and immunology clinic
Point of care (POC) clinical ultrasonography is used across multiple medical specialties to guide diagnosis and treatment, and to enhance the safety of invasive procedures. POC clinical ultrasonography is defined as a focused ultrasonographic examination, performed and interpreted by the treating clinician, to answer a specific question or to guide a procedure.1 Emergency department physicians were early adopters of POC ultrasonography in the late 1990 ’s; since then, technological advances have resulted in enhanced portability, improved image quality, and user-friendly interfaces, expanding the use of POC ultrasonog...
Source: Annals of Allergy, Asthma and Immunology - February 15, 2019 Category: Allergy & Immunology Authors: Samira Jeimy, Andrew Wong-Pack, Shafaz Veetil, Harold Kim Tags: Review Source Type: research

Drug Induced Enterocolitis Syndrome (DIES): a clinical entity which deserves more awareness
Drug induced enterocolitis syndrome (DIES) is a rare, non-IgE mediated hypersensitivity reaction provoked by drugs which can be severe and lead to shock. Despite the potential severity of the reactions, awareness of DIES is low. In contrast, enterocolitis syndrome induced by food proteins (FPIES) has been better documented. Previous studies have reported the occurrence of hypovolemic shock in approximately 15% of reactions, which indicates that FPIES is a potentially life threating disease.(1) To increase clinical awareness on DIES we here report a case of a child who was referred to our pediatric allergy clinic and was di...
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: A.O.J. Van Thuijl, L.J. Landzaat, O. Liem, J.A.M. Emons, N.J.T. Arends Tags: Letters Source Type: research

Pro-Con Debate: Component resolved diagnostic testing is not useful for making food allergy diagnoses
Funding: none (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: Matthew Greenhawt. Tags: Perspective Source Type: research

Con: OIT is safe/better than food avoidance
Food allergy (FA) is well-recognized as a major public health problem, affecting 8% of children and 5% of adults in the industrialized countries.1 Despite the relatively high prevalence of this disorder, there is unfortunately no definitive cure. For a long time, the classical approach for the management of IgE-mediated FA has been strict food avoidance and the prescription of epinephrine auto-injector in case of accidental reaction. Regular oral food challenges (OFC) are performed in order to assess spontaneous tolerance acquisition. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: Braun Camille, Caubet Jean-Christoph Tags: Perspective Source Type: research

Drug Hypersensitivity Reactions in the Americas: Similarities and Differences
Drugs are the most frequent cause of fatal anaphylaxis worldwide(1). The prevalence of adverse drug reactions (ADRs), including allergy, is known to be related to drug exposure frequency, gender, age, ethnicity and genetic factors, and it varies according to the classes of drugs, definitions of hypersensitivity reactions (HRs) and study design. Drug usage patterns vary significantly with time and geography, both across large countries and around the world(1-3). (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: Pedro Giavina-Bianchi, Edgardo Jares, Marcelo Vivolo Aun, Bernard Thong Source Type: research

From the pages of AllergyWatch May 2019
Head and Neck, MOC: (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: Stanley M. Fineman, David A. Khan, Chitra Dinakar Source Type: research

African American Ancestry Contribution to Asthma and Atopic Dermatitis
Despite advances in therapeutics and a better understanding of environmental risk factors, racial disparities in both asthma and atopic dermatitis (AD) are profound, and cannot be explained by non-genetic factors alone1,2. Disparities are compounded by a disproportionate under-representation of minority populations in genetic and pharmacogenetic studies of asthma and AD. As a result, genetic risk factors for these clinical conditions are much less well understood in African ancestry populations compared to European populations. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 14, 2019 Category: Allergy & Immunology Authors: Michelle Daya, Kathleen C. Barnes Tags: Review Source Type: research

Trends in hospitalizations related to anaphylaxis, angioedema and urticaria in the United States.
PMID: 30769181 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 12, 2019 Category: Allergy & Immunology Authors: Shrestha P, Dhital R, Poudel D, Donato A, Karmacharya P, Craig T Tags: Ann Allergy Asthma Immunol Source Type: research

Does angioedema influence the quality of life in chronic spontaneous urticaria patients?
PMID: 30769182 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 12, 2019 Category: Allergy & Immunology Authors: Oles-Krykowska A, Badura-Brzoza K, Brzoza Z Tags: Ann Allergy Asthma Immunol Source Type: research

Trends in hospitalizations related to anaphylaxis, angioedema and urticaria in the United States
Allergic disorders are a common clinical disorders with high rates of health care usage.1 Studies from developed countries have suggested an increasing prevalence of allergic diseases. 2 –4 However, the data on the epidemiology of anaphylaxis, angioedema and urticaria are limited, with only small cohort studies available. 1,4 Recent studies from the United Kingdom (UK) and Australia have noted marked increase in hospitalizations related to urticaria, angioedema and anaphylaxis.1,4 Epidemiological study and incidence data of these conditions, however, depend on several factors, including diagnostic criteria used, vari...
Source: Annals of Allergy, Asthma and Immunology - February 12, 2019 Category: Allergy & Immunology Authors: Pragya Shrestha, Rashmi Dhital, Dilli Poudel, Anthony Donato, Paras Karmacharya, Timothy Craig Source Type: research

Does angioedema influence the quality of life in chronic spontaneous urticaria patients?
Chronic spontaneous urticaria (CSU) symptoms are wheals in a number of cases accompanied by recurrent angioedema. The proportion of CSU patients manifesting both wheals and angioedema and those reporting only one type of symptoms is different - a similar number of patients experience both symptoms or wheals only, whereas 1 –13% experience angioedema only1,2. Symptoms of CSU have a detrimental influence on patients’ quality of life. Additionally, the coexistence between angioedema symptoms and wheals is related to prolonged disease duration2. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 12, 2019 Category: Allergy & Immunology Authors: A. Oles-Krykowska, K. Badura-Brzoza, Z. Brzoza Tags: Letters Source Type: research

Characteristics of Inner City Children with Life-Threatening Asthma.
PMID: 30742915 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Bollinger ME, Butz A, Tsoukleris M, Lewis-Land C, Mudd S, Morphew T Tags: Ann Allergy Asthma Immunol Source Type: research

Emerging Triggers of FPIES: Lessons from a Pediatric Cohort of 74 Children in the US.
PMID: 30742916 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Blackman AC, Anvari S, Davis CM, Anagnostou A Tags: Ann Allergy Asthma Immunol Source Type: research

Eliminating health disparities in asthma: are we at the end of the beginning?
;n JC PMID: 30742917 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Rosas-Salazar C, Celedón JC Tags: Ann Allergy Asthma Immunol Source Type: research

Eliminating health disparities in asthma: are we at the end of the beginning?
Health equity, defined as “the attainment of the highest level of health for all people”,1 continues to be a fundamental but difficult-to-achieve goal in the United States (U.S.), where some racial and ethnic minority groups are disproportionately affected by respiratory diseases such as asthma. Indeed, the prevalence of asthma is higher in Puerto Ricans (14.3%) and African Americans (11.6%) than in non-Hispanic whites (8.3%) or Mexican-Americans (5.7%).2 Moreover, Puerto Ricans and African Americans have higher morbidity and mortality from asthma than non-Hispanic whites2,3. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Christian Rosas-Salazar, Juan C. Celed ón Tags: Perspective Source Type: research

Characteristics of Inner City Children with Life-Threatening Asthma
Poor children living in US inner cities have high prevalence of asthma as well as asthma related morbidity and mortality.(1-3) In 2013, there were 3,640 deaths due to asthma in the US; a rate of 1.1 deaths per 100,000 population.(4) Between 2007-2009, the death rate for African Americans aged 0 –14 years was almost eight times greater than for whites in that age group(3). Several risk factors have been identified for fatal and near fatal asthma including a prior asthma admission to an intensive care unit (ICU), overuse of short acting beta agonists, underutilization of controller medicat ion, poor recognition of asth...
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Mary Elizabeth Bollinger, Arlene Butz, Mona Tsoukleris, Cassia Lewis-Land, Shawna Mudd, Tricia Morphew Source Type: research

Emerging Triggers of FPIES: Lessons from a Pediatric Cohort of 74 Children in the US
Food protein-induced enterocolitis syndrome (FPIES) is a rare non-IgE mediated gastrointestinal food-induced allergic disorder occurring predominantly in infants and young children. Common food triggers and the natural history of FPIES vary according to geographic location. It is a serious condition that is still under-recognized, resulting in a delay in diagnosis and appropriate management. FPIES is characterized by delayed onset of repetitive vomiting occurring approximately 1 to 4 hours after food ingestion. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 8, 2019 Category: Allergy & Immunology Authors: Andrea C. Blackman, Sara Anvari, Carla M. Davis, Aikaterini Anagnostou Source Type: research

Asthma Status and Risks among Lesbian, Gay, and Bisexual Adults in the United States: A Scoping Review.
PMID: 30721759 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 2, 2019 Category: Allergy & Immunology Authors: Veldhuis CB, Bruzzese JM, Hughes TL, George M Tags: Ann Allergy Asthma Immunol Source Type: research

Asthma Status and Risks among Lesbian, Gay, and Bisexual Adults in the United States: A Scoping Review
Asthma is uncontrolled in up to 71% of adolescents and adults,1 resulting in higher healthcare costs, more school and work absences, and higher mortality.1,2 Sexual minority adults (SM; e.g., people who identify as lesbian, gay, or bisexual, or who have same-sex partners) have higher rates of asthma than heterosexual counterparts.3,4 However, it is unclear whether rates and risk factors differ by sexual identity. To address this critical knowledge gap, we conducted a scoping review to systematically search relevant literature following current guidelines. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 2, 2019 Category: Allergy & Immunology Authors: Cindy B. Veldhuis, Jean-Marie Bruzzese, Tonda L. Hughes, Maureen George Tags: Letters Source Type: research

Presentation and natural history of progestogen hypersensitivity.
CONCLUSION: Although the medical literature on progestogen hypersensitivity is limited to case reports and small case series, significant heterogeneity exists in clinical presentation among patients. PMID: 30712576 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Foer D, Buchheit KM Tags: Ann Allergy Asthma Immunol Source Type: research

Associations of unsafe, unsupportive, and underdeveloped neighborhoods with atopic dermatitis in US children.
CONCLUSION: US children residing in unsafe, unsupportive, or underdeveloped neighborhoods have higher prevalence and severity of AD. PMID: 30712577 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: McKenzie C, Silverberg JI Tags: Ann Allergy Asthma Immunol Source Type: research

Coexistent TBX1 mutation and chromosomal 20q13.13-q13.2 duplication in an infant with abnormal T-cell receptor rearrangement circle newborn screening results.
PMID: 30712578 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Lam JK, Braddock SR, Huddleston CB, Knutsen AP Tags: Ann Allergy Asthma Immunol Source Type: research

The Best of 2018 in the Annals of Allergy, Asthma, and Immunology: The Editors' Choices.
PMID: 30711033 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Marshall GD, Leung DYM, Ellis A, Nowak-Wegrzyn A, Castells M, Grayson M, Greenhawt M, Lieberman J, Oppenheimer J, Spergel J Tags: Ann Allergy Asthma Immunol Source Type: research

Sex and allergic diseases.
PMID: 30711034 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Nowak-Wegrzyn A, Ellis A, Castells M Tags: Ann Allergy Asthma Immunol Source Type: research

Author's reply.
PMID: 30711035 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Scherzer R Tags: Ann Allergy Asthma Immunol Source Type: research

A critical need: Increasing interest in the field of allergy and immunology.
PMID: 30711036 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Okafor L, Nathan M Tags: Ann Allergy Asthma Immunol Source Type: research

Is hereditary angioedema related to an increased risk of atherosclerosis?
PMID: 30711037 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Bassareo PP, Firinu D, Del Giacco S Tags: Ann Allergy Asthma Immunol Source Type: research

A critical need
We read with interest Dr Scherzer ’s1 article on the downward trend in applicants for allergy and immunology (AI) fellowship programs, and we commend Dr Scherzer for exploring approaches to increase interest. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Lauren Okafor, Miriam Nathan Tags: Correspondence Source Type: research

---
This book is part of a series that provides detailed reviews of advances in specific immunologic topics. It is divided into 5 chapters authored by experts in the field: 1) Eosinophil Development, Disease Involvement, and Therapeutic Suppression; 2) Unexpected Roles for Intracellular Complement in the Regulation of Th1 Responses; 3) Chemokines: Critical Regulators of Memory T Cell Development, Maintenance, and Function; 4) Molecular Classification of Primary Immunodeficiencies of T Lymphocytes; 5) Molecular Aspects of Allergens and Allergy. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Jennifer R. Yonkof, Mitchell Grayson Tags: Book Review Source Type: research

Is hereditary angioedema related to an increased risk of atherosclerosis?
We paid close attention in reading the interesting paper by Nebenf ührer et al,1 whose findings excluded the presence of endothelial dysfunction in hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) patients. Their results are opposite of those recently published by our research group.2 Because the issue is important, impaired endothelial function be ing correlated with future occurrences of adverse cardiovascular events and cardiac death,3 we think that a few points should be worthy of debate. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Pier Paolo Bassareo, Davide Firinu, Stefano Del Giacco Tags: Correspondence Source Type: research

Author's reply
I thank Okafor et  al for their interest in our article “A Critical Need: Increasing Interest in the Field of Allergy and Immunology in Medical Students and Residents” and their thoughtful questions. The general downward trend in the number of candidates per fellowship position in the Allergy and Immunology (AI) fellowship training program match from 1.7 in 2008 to 1.0 in 2018 is concerning and an area of discussion and planning for many in the field.1,2 A study by Macy et al3 revealed that the key time in the decision-making process on whether to pursue fellowship training could be in the final years...
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Rebecca Scherzer Tags: Correspondence Source Type: research

The Best of 2018 in the Annals of Allergy, Asthma, and Immunology
The editors of the Annals of Allergy, Asthma, and Immunology considered more than 750 submissions for publication in 2018. From that number, we accepted 323 articles, letters, and other features to be included in the 12 issues of the 2018 Annals. Every feature was carefully scrutinized before acceptance, and there were multiple articles that were acceptable but were not used because of space constraints (ie, we do not have room to publish all of the acceptable manuscripts we received). Accordingly, the 323 are already the “best” of the submissions that were submitted last year. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Gailen D. Marshall, Donald Y.M. Leung, Anne Ellis, Anna Nowak-Wegrzyn, Marianna Castells, Mitchell Grayson, Matthew Greenhawt, Jay Lieberman, John Oppenheimer, Jonathan Spergel Tags: A Year in Review Source Type: research

Sex and allergic diseases
Differences between women and men are pervasive in human biology, including the immune system.1 The direct effects of sex hormones have not been comprehensively evaluated; however, lymphocytes, monocytes, eosinophils, basophils, and mast cells are known to express receptors for sex hormones.2 There is also evidence to suggest that estrogens act as enhancers of humoral responses, autoimmunity, mast cell reactivity, and delayed type IV allergic reactions, whereas androgens, progesterone, and glucocorticoids may have an immunosuppressive effect. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Anna Nowak-Wegrzyn, Anne Ellis, Mariana Castells Tags: Editorial Source Type: research

Information for Readers
(Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Source Type: research

Table of Contents
(Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Source Type: research

Information for Authors
(Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Source Type: research

Editorial Board
(Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Source Type: research

"To Biologic or Not to Biologic?: The Question of Cost-Effectiveness".
"To Biologic or Not to Biologic?: The Question of Cost-Effectiveness". Ann Allergy Asthma Immunol. 2019 Jan 28;: Authors: Anderson WC, Szefler SJ PMID: 30703438 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 28, 2019 Category: Allergy & Immunology Authors: Anderson WC, Szefler SJ Tags: Ann Allergy Asthma Immunol Source Type: research

Economic burden of food allergy- A systematic review.
PMID: 30703439 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 28, 2019 Category: Allergy & Immunology Authors: Bilaver LA, Doshi P, Chadha AS, O'Dweyer L, Gupta RS Tags: Ann Allergy Asthma Immunol Source Type: research

Economic burden of food allergy- A systematic review
Food allergy (FA) is a life-threatening condition that is a growing health concern worldwide. Currently in the United States, 8% of children have a parent-reported FA.1 Much of the epidemiological work on FA has focused primarily on children; however, recent estimates have found that 10.8% of adults in the US have a self-reported FA.2 Furthermore, numerous studies have estimated the prevalence of FA in children from countries across Europe including France (6.7%),3 Greece (5.2%),4 and Sweden (6.8%). (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 28, 2019 Category: Allergy & Immunology Authors: Lucy A. Bilaver, Priyam Doshi, Avneet S. Chadha, Linda O ’Dweyer, Ruchi S. Gupta Tags: Review Source Type: research

“To Biologic or Not to Biologic?: The Question of Cost-Effectiveness”
As of 2018, the FDA had approved five biologics for the treatment of asthma – omalizumab, mepolizumab, reslizumab, benralizumab, and dupilumab. All five of these biologics are designated for the treatment of severe asthma in patients with a TH2-driven phenotype, either allergic or eosinophilic. In clinical trials, biologics have demonstrated efficacy to decrease the frequ ency of asthma exacerbations, unplanned health utilization including ED visits and hospitalizations, and chronic oral steroid use in severe asthmatic patients1. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 28, 2019 Category: Allergy & Immunology Authors: William C. Anderson, Stanley J. Szefler Tags: Review Source Type: research

From the pages of AllergyWatch.
PMID: 30685561 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: Oppenheimer JJ, Lang DM, Fineman SM Tags: Ann Allergy Asthma Immunol Source Type: research

Chronic Itch Management: Therapies Beyond Those Targeting the Immune System.
PMID: 30685562 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: Fowler E, Yosipovitch G Tags: Ann Allergy Asthma Immunol Source Type: research

Pattern of Medication Use in Children with Very Poorly Controlled Asthma.
PMID: 30685563 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: Butz AM, Morphew T, Bellin M, Bollinger ME, Tsoukleris M Tags: Ann Allergy Asthma Immunol Source Type: research

From the pages of AllergyWatch
J Allergy Clin Immunol Pract. 2018;6:1274-1286 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: John J. Oppenheimer, David Michael Lang, Stanley M. Fineman Source Type: research

Chronic Itch Management: Therapies Beyond Those Targeting the Immune System
Itch, a sensation that leads to a desire to scratch, becomes chronic when it persists for more than 6 weeks.1 Chronic itch can be debilitating and lead to a significantly reduced quality of life. It affects sleep, mood, and can cause symptoms of anxiety and depression.2 Pruritus may be perpetuated by inflammatory conditions, as seen in atopic dermatitis and psoriasis. However, chronic pruritus may not always have an inflammatory component, and therefore requires treatments that do not work on the immune system, but instead target the nerves. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: Emilie Fowler, Gil Yosipovitch Tags: Review Source Type: research

Pattern of Medication Use in Children with Very Poorly Controlled Asthma
Tables: 1 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 24, 2019 Category: Allergy & Immunology Authors: Arlene M. Butz, Tricia Morphew, Melissa Bellin, Mary Elizabeth Bollinger, Mona Tsoukleris Tags: Letters Source Type: research

A Peripheral Cause of Asthma: Peripheral T-cell Lymphoma.
PMID: 30684735 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 23, 2019 Category: Allergy & Immunology Authors: Ramonell RP, Kuruvilla M, Sica G, Bag R, Eun-Hyung Lee F Tags: Ann Allergy Asthma Immunol Source Type: research

Ethanol LOCK & Immunoglobulin LOAD: Improving the Clinical Course of Tricho-hepato-enteric Syndrome.
Ethanol LOCK & Immunoglobulin LOAD: Improving the Clinical Course of Tricho-hepato-enteric Syndrome. Ann Allergy Asthma Immunol. 2019 Jan 23;: Authors: Popadiuk CA, Lindsey DR, Jones MU, Mikita CP PMID: 30684736 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 23, 2019 Category: Allergy & Immunology Authors: Popadiuk CA, Lindsey DR, Jones MU, Mikita CP Tags: Ann Allergy Asthma Immunol Source Type: research

The Evaluation of Tryptase after Subcutaneous Immunotherapy-Associated Systemic Reactions.
PMID: 30684737 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - January 23, 2019 Category: Allergy & Immunology Authors: Szari S, Wong PH, Crisp HC, Champoux E, Rans TS, Coop CA Tags: Ann Allergy Asthma Immunol Source Type: research