Annals of Allergy, Asthma and Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

What lessons are learned?
Hereditary angioedema (HAE) is a rare genetic disorder (1:50,000-100,000 in the United States) characterized by unpredictable and recurrent episodes of swelling without hives in different parts of the body.1 Generally, it is caused by a deficiency or a loss of function of C1 esterase inhibitor (C1 INH) because of a mutation in SERPING1.1 Moreover, HAE can lead to significant morbidity including death because of laryngeal swelling and asphyxia.1,2 There is a limited number of published case series. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Sevdenur Keskin, Yosif Pak, Jocelyn Celestin Tags: Letters Source Type: research

What should be the outcome of biologic treatment in asthma: "remission on treatment" or "super-responder"
Recently, the definition of remission in asthma has started to be used and discussed frequently. Descriptions such as remission on-treatment, remission off-treatment, and criteria reflecting these concepts have been defined. However, since there are different opinions among experts on these remission criteria, different remission criteria have been defined. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: G ülden Paçacı Çetin, İnsu Yılmaz Tags: Letters Source Type: research

What lessons are learned? our changing practice during thirty years of hereditary angioedema treatment
Hereditary angioedema (HAE) is a rare genetic disorder (1:50,000 – 100,000 in the US) characterized by unpredictable and recurrent episodes of swelling without hives in different parts of the body1. Generally, it is caused by a deficiency or a loss of function of C1 esterase inhibitor (C1 INH) due to a mutation in SERPING11. HAE can lead to significant morbidit y including death due to laryngeal swelling and asphyxia1, 2. There is a limited number of published case series. We are here reporting some lessons learned from our 30-year experience with our HAE patient population. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Sevdenur Keskin, Yosif Pak, Jocelyn Celestin Tags: Letters Source Type: research

What should be the outcome of biological treatment in asthma: "Remission on Treatment" or "Super-responder"
Recently, the definition of the remission in asthma has started to be used and discussed frequently. Descriptions such as remission on treatment, remission off treatment, and criteria reflecting these concepts have been defined. However, since there are different opinions among experts among these remission criteria, different remission criteria have been defined. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: G ülden Paçacı Çetin, İnsu Yılmaz Source Type: research

Establishment of fluorescence multi-flow cytometric immunoassay for the simultaneous quantitative detection of six allergen-sIgE antibodies
The in vitro specific IgE (sIgE) assays now commonly used in clinical laboratories are not only time-consuming and expensive, but also require a large number of serum samples. To address these limitations, a novel fluorescent microsphere-based multiplex flow cytometric immunoassay was developed. This innovative assay enables rapid and simultaneous quantitative detection of multiple allergen-sIgE antibodies. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Yuanmin Sun, Yixian Li, Jian Hu, Xiaohui Yang, Bei Zhang, Xueyan Wang, Huiqiang Li, Yang Yu Tags: Original Article Source Type: research

Lower paraspinal muscle density is associated with small airway dysfunction in women with persistent asthma
Patients with asthma exhibit lower paraspinal muscle density (PSMD) which is reflective of increased skeletal muscle adiposity. Moreover, in women with persistent asthma, lower PSMD is associated with longitudinal decline in spirometry.(1) Notably in the same study however, there were no differences in baseline spirometry values according to PSMD. Pointedly, high intramuscular fat infiltration is associated with greater systemic leptin, lower systemic adiponectin and increased expression of tumour necrosis factor alpha, all of which have been implicated in asthma.(2) This is of particular interest as the targeted managemen...
Source: Annals of Allergy, Asthma and Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Rory Chan, Chary Duraikannu, Mohamed Jaushal Thouseef, Brian Lipworth Tags: Letters Source Type: research

Proteomic and metabolomic proof of concept for unified airways in chronic rhinosinusitis and asthma
CONCLUSION: Proteomics and metabolomics reveal upper and lower airway unity. Asthma pathway-related proteins PRG2 and EPX from the upper airway could be used to assess the potential risk of lower airway dysfunction in CRSwNP.PMID:38382675 | DOI:10.1016/j.anai.2024.02.008 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 21, 2024 Category: Allergy & Immunology Authors: Yao Yao Yujuan Yang Jianwei Wang Pengyi Yu Jing Guo Luchao Dong Cai Wang Pengfei Liu Yu Zhang Xicheng Song Source Type: research

Preparing Adolescents for Independent Asthma Management: Gaps and Opportunities
Ann Allergy Asthma Immunol. 2024 Feb 17:S1081-1206(24)00086-3. doi: 10.1016/j.anai.2024.02.010. Online ahead of print.NO ABSTRACTPMID:38373580 | DOI:10.1016/j.anai.2024.02.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 19, 2024 Category: Allergy & Immunology Authors: Suzanne Y Ngo Samantha Bothwell John T Brinton William C Anderson Source Type: research

Managing Anaphylaxis Away from Home
Ann Allergy Asthma Immunol. 2024 Feb 17:S1081-1206(24)00091-7. doi: 10.1016/j.anai.2024.02.015. Online ahead of print.NO ABSTRACTPMID:38373581 | DOI:10.1016/j.anai.2024.02.015 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 19, 2024 Category: Allergy & Immunology Authors: Theresa A Bingemann Marcus Shaker Gena Heng Matthew Greenhawt Source Type: research

Proteomic and metabolomic proof of concept for unified airways in chronic rhinosinusitis and asthma
Pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) with comorbid asthma remains unclear. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 19, 2024 Category: Allergy & Immunology Authors: Yao Yao, Yujuan Yang, Jianwei Wang, Pengyi Yu, Jing Guo, Luchao Dong, Cai Wang, Pengfei Liu, Yu Zhang, Xicheng Song Tags: Original Article Source Type: research

Early solid introduction to prevent IgE-mediated food allergy should continue unabated while we learn more about FPIES prevalence
Ann Allergy Asthma Immunol. 2024 Feb 16:S1081-1206(24)00083-8. doi: 10.1016/j.anai.2024.02.012. Online ahead of print.NO ABSTRACTPMID:38369255 | DOI:10.1016/j.anai.2024.02.012 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 18, 2024 Category: Allergy & Immunology Authors: Linlei Ye Stephanie C Erdle Elissa M Abrams Edmond S Chan Source Type: research