Perinatal probiotic intervention prevented allergic disease in a Caesarean ‐delivered subgroup at 13‐year follow‐up
ConclusionsProbiotic intervention protected Caesarean ‐delivered subgroup from allergic disease and eczema, but not the total cohort.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 25, 2018 Category: Allergy & Immunology Authors: S Kallio,
A. K Kukkonen,
E Savilahti,
M Kuitunen Tags: Original Article ‐Clinical Allergy Source Type: research
Impact of Parental Asthma, Prenatal Maternal Asthma Control and Vitamin D Status on Risk of Asthma and Recurrent Wheeze in 3 ‐Year Old Children
Conclusion and Clinical RelevanceCareful attention to maternal asthma control, monitoring vitamin D status and correcting insufficiency at early pregnancy and maintaining the sufficiency status throughout pregnancy have potential preventive roles in offspring asthma or recurrent wheeze.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 21, 2018 Category: Allergy & Immunology Authors: Hooman Mirzakhani,
Vincent J. Carey,
Robert Zeiger,
Leonard B. Bacharier,
George T. O'Connor,
Michael X. Schatz,
Nancy Laranjo,
Scott T. Weiss,
Augusto A. Litonjua Tags: Original Article ‐Asthma and Rhinitis Source Type: research
Individual Risk Assessment Tool for School Age Asthma Prediction in UK Birth Cohort
ConclusionMAAS APT is a simple asthma prediction tool which could easily be applied in clinical and research settings.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 16, 2018 Category: Allergy & Immunology Authors: Ran Wang,
Angela Simpson,
Adnan Custovic,
Phil Foden,
Danielle Belgrave,
Clare S Murray Tags: Original Article ‐Asthma and Rhinitis Source Type: research
Th2 cell differentiation from naive CD4+ T cells is enhanced by autocrine CC chemokines in atopic diseases
Conclusions& Clinical RelevanceThese data suggest that CCL17 and CCL22 produced by TSLP ‐primed naïve CD4+ T cells in asthma might contribute to an increase in Th2 cells via autocrine loops.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 15, 2018 Category: Allergy & Immunology Authors: Hirokuni Hirata,
Tatsuo Yukawa,
Ayae Tanaka,
Tomoyuki Miyao,
Takeshi Fukuda,
Yasutsugu Fukushima,
Kazuhiro Kurasawa,
Masafumi Arima Tags: Original Article ‐Basic Mechanisms in Allergic Disease Source Type: research
Follow ‐up of patients with negative drug provocation tests to betalactams
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 15, 2018 Category: Allergy & Immunology Authors: Anca Mirela Chiriac,
Antonino Romano,
Najah Ben Fadhel,
Francesco Gaeta,
Nicolas Molinari,
Michela Maggioletti,
Pascal Demoly Tags: Research Letter Source Type: research
Germination of pollen grains in the esophagus of individuals with eosinophilic esophagitis
ConclusionAlteration of the mucosal barrier in EoE might cause the penetration of pollen grains into the esophageal tissues. In EoE patients, anatomopathological studies searching for intrusion to plant foods and pollen, and specific ‐guided diet and immunotherapy after plant structures detection in biopsies, might be effective.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 12, 2018 Category: Allergy & Immunology Authors: Alicia Armentia,
Sara Mart ín Armentia,
Rafael Álvarez‐Nogal,
Blanca Martín Armentia,
Manuel José Gayoso,
Delia Fernández‐González Tags: Original Article ‐Clinical Mechanisms in Allergic Disease Source Type: research
Antihistamine ‐resistant chronic spontaneous urticaria: 1‐year data from the AWARE study
Conclusions& Clinical RelevanceThis study highlights a significant discrepancy between recommendations for managing CSU in international guidelines, and in real ‐world clinical practice in Germany.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 11, 2018 Category: Allergy & Immunology Authors: M. Maurer,
U. Raap,
P. Staubach,
G. Richter ‐Huhn,
A. Bauer,
E.M. Oppel,
U. Hillen,
D. Baeumer,
M. Reinhardt,
N. Chapman‐Rothe Tags: Original Article ‐Epidemiology of Allergic Disease Source Type: research
Traffic ‐related air pollution induces non‐allergic eosinophilic airway inflammation and cough hypersensitivity in guinea pigs
Conclusions& Clinical RelevanceTRAP exposures induced cough hypersensitivity and non ‐allergic eosinophilic inflammation of airways in guinea pigs. This study highlights the potential mechanisms of eosinophilia‐related chronic cough that can be induced by traffic‐related air pollution.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 11, 2018 Category: Allergy & Immunology Authors: Zhangfu Fang,
Chuqin Huang,
Junfeng(Jim) Zhang,
Jiaxing Xie,
Shouhui Dai,
Erjia Ge,
Juan Xiang,
Hongmei Yao,
Rongquan Huang,
Xinhui Bi,
Boguang Wang,
Nanshan Zhong,
Kefang Lai Tags: Original Article ‐Experimental Models of Allergic Disease Source Type: research
Variability of blood eosinophils in patients in a clinic for severe asthma
ConclusionIn an urban clinic for patients referred for uncontrolled asthma, blood measures of eosinophils were variable and showed differing patterns of variability. These data reinforce the need to perform repeated eosinophil blood measures for appropriate designation for therapeutic intervention.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 11, 2018 Category: Allergy & Immunology Authors: E Rakowski,
S Zhao,
M Liu,
S Bajaj,
N Durmus,
G Grunig,
M Curotto de Lafaille,
Y Wu,
J Reibman Tags: Original Article ‐Asthma and Rhinitis Source Type: research
Dividing neutrophils in subsets, reveals a significant role for activated neutrophils in the development of airway hyperreactivity
Conclusions& Clinical RelevanceThe present study introduces a new concept regarding the role of neutrophils and defines a novel direct link between a specific activated neutrophil subset and airway smooth muscle, establishing neutrophils as important players in the development of asthmatic airway hyperactivity.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 11, 2018 Category: Allergy & Immunology Authors: Sandra Ekstedt,
Jesper S äfholm,
Susanna Kumlien Georén,
Lars Olaf Cardell Tags: Original Article ‐Asthma and Rhinitis Source Type: research
The Basophil Activation Test reduces the need for a food challenge test in children suspected of IgE ‐mediated cow's milk allergy
Conclusions and Clinical RelevanceThe BAT seems reliable and cost ‐effective to diagnose patients with an IgE‐mediated cow's milk allergy. In IgE sensitized patients a BAT might replace a DBPCFC. For non‐IgE sensitized patients presenting with mild symptoms we propose to consider a (double‐blind) extended (time) challenge test at home.This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 8, 2018 Category: Allergy & Immunology Authors: Janneke Ruinemans ‐Koerts,
Yvonne Schmidt‐Hieltjes,
A d Jansen,
Huub F.J. Savelkoul,
Annejet Plaisier,
Petra van Setten Tags: Original Article ‐Clinical Allergy Source Type: research
Low dose provocation and skin tests in patients with hypersensitivity to Gadolinium ‐based contrast agents
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 8, 2018 Category: Allergy & Immunology Authors: Vannina Seta,
Hafida Gaouar,
Antoine Badaoui,
Camille Franc ès,
Annick Barbaud,
Angèle Soria Tags: Research Letter Source Type: research
Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation
Clinical&Experimental Allergy, EarlyView. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 5, 2018 Category: Allergy & Immunology Authors: Koa Hosoki,
Pawel Jaruga,
Toshiko Itazawa,
Leopoldo Aguilera-Aguirre,
Erdem Coskun,
Tapas K. Hazra,
Istvan Boldogh,
Miral Dizdaroglu,
Sanjiv Sur Source Type: research
Blocking antibodies induced by peanut oral and sublingual immunotherapy suppress basophil activation and are associated with sustained unresponsiveness
Clinical&Experimental Allergy,Volume 0, Issue ja, -Not available-. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - November 1, 2018 Category: Allergy & Immunology Authors: Kelly Orgel,
Caitlin Burk,
Johanna Smeekens,
Jada Suber,
Lakeya Hardy,
Rishu Guo,
A. Wesley Burks,
Michael Kulis Source Type: research
Fevipiprant, a DP2 Receptor Antagonist, Inhibits Eosinophil Migration Towards Mast Cells
Clinical&Experimental Allergy,Volume 0, Issue ja, -Not available-. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - October 31, 2018 Category: Allergy & Immunology Authors: Revital Shamri,
Gerald Dubois,
Veit J Erpenbeck,
David Mankuta,
David A Sandham,
Francesca Levi ‐Schaffer Source Type: research
