Development of Aspergillus protease with ovalbumin-induced allergic chronic rhinosinusitis model in the mouse.

CONCLUSION: Aspergillus protease combined with OVA induced more severe allergic inflammation in sinonasal mucosa compared with OVA alone and similar eosinophilia. This model could be more relevant to recalcitrant eosinophilic CRS in humans than OVA-induced allergic CRS. PMID: 25514482 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25514482?dopt=Abstract

Source: American Journal of Rhinology and Allergy - November 1, 2014 Category: ENT & OMF Authors: Kim JH, Yi JS, Gong CH, Jang YJ Tags: Am J Rhinol Allergy Source Type: research

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