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Infectious Disease: Aspergillus

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Total 481 results found since Jan 2013.

Stability of serum precipitins to Aspergillus fumigatus for the diagnosis of allergic bronchopulmonary aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA) reflects hypersensitivity and an exaggerated immune response to Aspergillus fumigatus. ABPA typically occurs in individuals with airway diseases such as asthma or cy...
Source: Allergy, Asthma and Clinical Immunology - September 3, 2020 Category: Allergy & Immunology Authors: Kevin S. K. Lau, Chantane Yeung and Chris Carlsten Tags: Research Source Type: research

Insufficient allergy diagnostics in severe asthmatic patients in Germany
Conference abstracts
Source: The Aspergillus Website - updates - September 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Fetal and early postnatal lead exposure measured in teeth associates with infant gut microbiota.
CONCLUSIONS: The observed associations between lead exposure and infant gut microbiota could play a role in the impact of lead on childhood development. Given the paucity of research examining these associations in humans-particularly for fungal microbiota-further investigation is needed. PMID: 32871381 [PubMed - as supplied by publisher]
Source: Environment International - August 28, 2020 Category: Environmental Health Authors: Sitarik AR, Arora M, Austin C, Bielak LF, Eggers S, Johnson CC, Lynch SV, Kyun Park S, Hank Wu KH, Yong GJM, Cassidy-Bushrow AE Tags: Environ Int Source Type: research

Study of aero-allergen sensitization in subjects with naso-bronchial allergy in a tertiary care centre from India
Conference abstracts
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

IgE-mediated occupational allergy to fungus among paddy field farmers of West Bengal, India: an aeromycological & immunological approach
IgE-mediated occupational allergy to fungus among paddy field farmers of West Bengal, India: an aeromycological& immunological approachConference abstracts
Source: The Aspergillus Website - updates - August 5, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Differential response to biologics in a patient with severe asthma and ABPA: a role for dupilumab?
Allergic bronchopulmonary aspergillosis (ABPA) is a severe hypersensitivity reaction to aspergillus species colonizing the airways of patients with asthma or cystic fibrosis. Biologics including anti-IgE and a...
Source: Allergy, Asthma and Clinical Immunology - June 26, 2020 Category: Allergy & Immunology Authors: Carlo M ümmler, Bernd Kemmerich, Jürgen Behr, Nikolaus Kneidinger and Katrin Milger Tags: Case report Source Type: research

Bacterial and Fungal Preclinical Services Resources, Natl. Inst. of Allergy and Infectious Diseases
Conference abstracts
Source: The Aspergillus Website - updates - June 19, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

A multi ‐institutional review of outcomes in biopsy‐proven chronic invasive fungal sinusitis
ConclusionWe present a multi ‐institutional case‐series of CIFS and long‐term follow‐up. ANC<1000 at time of diagnosis and recent chemotherapy (within 1 month of diagnosis) are associated with poorer survival, whereas a rising ANC>1000 is associated with improved survival at 12 months. Further prospective studies are needed to further define factors that affect outcomes.
Source: International Forum of Allergy and Rhinology - April 12, 2020 Category: Allergy & Immunology Authors: Ian M. Humphreys, Grace M. Wandell, Craig Miller, Aakanksha Rathor, Rodney A. Schmidt, Justin H. Turner, Peter H. Hwang, Greg E. Davis Tags: ORIGINAL ARTICLE Source Type: research

Increased chitotriosidase is associated with aspergillus and frequent exacerbations in south-east asians with bronchiectasis.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS. Chest. 2020 Mar 14;: Authors: Poh TY, Tiew PY, Hou Lim AY, Thng KX, Binte Mohamed Ali NA, Narayana JK, Aogáin MM, Tien Z, Chew WM, Wai Chan AK, Keir HR, Dicker AJ, Hassan TM, Xu H, Tee AKH, Ong TH, Koh MS, Abisheganaden JA, Chalmers JD, Chotirmall SH Abstract BACKGROUND: and Research Question: Chitinase activity is an important innate immune defence mechanism against infection including fungi. The two human chitinases: chitotriosidase (CHIT1) and acidic mammalian chitinase (AM...
Source: Chest - March 13, 2020 Category: Respiratory Medicine Authors: Poh TY, Tiew PY, Hou Lim AY, Thng KX, Binte Mohamed Ali NA, Narayana JK, Aogáin MM, Tien Z, Chew WM, Wai Chan AK, Keir HR, Dicker AJ, Hassan TM, Xu H, Tee AKH, Ong TH, Koh MS, Abisheganaden JA, Chalmers JD, Chotirmall SH Tags: Chest Source Type: research

MicroRNA-targeted proteomic profiling predicts potential biomarkers of Aspergillus versicolor exposure
Personal exposure to fungal bioaerosols within damp indoor environments is associated with adverse respiratory health effects. Pathway analysis of proteomic and RNA alterations following exposure to Aspergillus versicolor, a prominent indoor fungal contaminant, identified proteins and microRNAs not previously associated with fungal exposure.
Source: Journal of Allergy and Clinical Immunology - January 31, 2020 Category: Allergy & Immunology Authors: Tara Croston, Mark Barnes, Angela Lemons, Dori Germolec, Donald Beezhold, Brett Green Source Type: research

A. felis in Patient With Chronic Granulomatous Disease A. felis in Patient With Chronic Granulomatous Disease
This report describes a case of Aspergillus felis infection in a patient with chronic granulomatous disease. How was this infection identified and successfully treated?Emerging Infectious Diseases
Source: Medscape Allergy Headlines - January 6, 2020 Category: Allergy & Immunology Tags: Infectious Diseases Journal Article Source Type: news

Is fungal sensitisation associated with exacerbation-prone or severe preschool wheezing?
Discussion: Our preliminary data suggests that fungal sensitisation in preschoolers is a) associated with more intense preventer treatement use and b) has a trend towards subsequent hospitilisations. A larger data set is being collected to further explore a) fungal sensitisation in relation to exacerbations and b) whether 0.35kUA/L is a useful cut-off to determine sensitisation in preschoolers.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Holden, K., Lo, D., Gaillard, E. Tags: Paediatric asthma and allergy Source Type: research

Aspergillus sensitization and aspergillus-associated diseases in a sample of patients with severe asthma
Conclusions: The severe asthmatic patients examined had a high prevalence of Aspergillus sensitization and of Aspergillus-associated diseases as ABPA (26%) and CPA (26%). It has to be demonstrated the benefit of an early recognition and treatment of these diseases on the course of asthma.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Bucca, C., De Blasio, F., Dassetto, D., Ambrosanio, R., Rella, A., Riberi, L., Solidoro, P. Tags: Allergy and immunology Source Type: research

Retrospective study on the combined use of voriconazole and prednisolone in the treatment of acute allergic bronchopulmonary aspergillosis (ABPA)
Three years ago we started treating patients diagnosed with ABPA, an allergic lung disease provoked by Aspergillus fumigatus (Af), with a combined therapy of voriconazole and prednisolone. We used voriconazole at a dose of 200 mg twice a day for 4 months, while the initial prednisolone dose was 0.75 mg/kg/day for 1 month, then 0.25 mg/kg/day for 1 month, then progressive tapering (5 mg each fortnight) until the minimum dose of 5 mg/day, maintained until the fourth month. We evaluated patients at 6 months from the end of therapy. We enrolled 25 patients in the disease acute phase, who had never used azol therapy before, wit...
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Bini, F., Visca, D., Grassi, N., De Lauretis, A., Spanevello, A., Vaghi, A. Tags: Allergy and immunology Source Type: research