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Infectious Disease: Aspergillus
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Total 481 results found since Jan 2013.
Clinico-demographic, radiological and immunological profile of allergic bronchopulmonary aspergillosis in a tertiary care institute of east India.
Conclusion: There was no significant association between lung function abnormalities and eosinophil count. ABPA-S was the most common finding among ABPA patients. High eosinophil count is associated with high incidence of bronchiectasis and hyper attenuated mucus (HAM) although severity of bronchiectasis is not directly related to higher peripheral eosinophil count. There may be some correlation between peripheral eosinophil count and total IgE but no significant correlation with aspergillus specific IgE.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Shankar, M., Ejazi, A., Chaubey, S., Kumar, D. Tags: 05.03 - Allergy and immunology Source Type: research
The epidemiology of sensitization to perennial aeroallergens in adult patients with severe asthma in Belgium. The Belgian IgE (BEIgE) study
Conclusions: Although assessment of the clinical relevance of the sensitizations was not an aim of the study, our results indicate an underestimation in the detection of sensitizations to PAs in the SA population studied. The obtained ranking list of PAs will optimize the diagnostic and therapeutic management of SA patients.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Schleich, F., Gurdain, S., Maury, E., Van Schoor, J. Tags: 05.03 - Allergy and immunology Source Type: research
The importance of aeroallergen sensitivity in children with cystic fibrosis
CONCLUSION: Aeroallergen sensitivity was detected in approximately one-third of CF patients. Although it has been emphasized in studies that environmental factors may have an impact on lung functions and clinical conditions in CF, the effect of allergens other than AF sensitivity may be less important compared to other environmental factors, such as the presence of bacterial colonization.PMID:36433750 | DOI:10.15586/aei.v50iSP3.764
Source: Allergologia et Immunopathologia - November 26, 2022 Category: Allergy & Immunology Authors: Özge Atay Suna Asilsoy Seda Şirin Köse Gizem Atakul Serdar Al Özge Kangallı Boyacioğlu Nevin Uzuner Özkan Karaman Source Type: research
Optimizing cultivation conditions for highest expression of fungal allergens
CONCLUSION: This study shows the impact of different environmental conditions on the expression of the fungal allergens Alt a 1, Ulo c 1, and different fungal enolases. It further, broadens the knowledge about the expression pattern of the major fungal allergens Alt a 1 and Ulo c 1. Information obtained in this study will help to optimize fungal cultivation to produce diagnostic fungal extracts of high quality and therefore improve diagnosis' specificity and sensitivity.PMID:36435304 | DOI:10.1016/j.anai.2022.11.017
Source: Annals of Allergy, Asthma and Immunology - November 26, 2022 Category: Allergy & Immunology Authors: Sandra Pfeiffer Margarete Focke-Tejkl Katja Sterflinger Ines Swoboda Source Type: research
The importance of aeroallergen sensitivity in children with cystic fibrosis
CONCLUSION: Aeroallergen sensitivity was detected in approximately one-third of CF patients. Although it has been emphasized in studies that environmental factors may have an impact on lung functions and clinical conditions in CF, the effect of allergens other than AF sensitivity may be less important compared to other environmental factors, such as the presence of bacterial colonization.PMID:36433750 | DOI:10.15586/aei.v50iSP3.764
Source: Allergologia et Immunopathologia - November 26, 2022 Category: Allergy & Immunology Authors: Özge Atay Suna Asilsoy Seda Şirin Köse Gizem Atakul Serdar Al Özge Kangallı Boyacioğlu Nevin Uzuner Özkan Karaman Source Type: research
Progress and challenges in fungal lung disease in cystic fibrosis
Purpose of review
This review is an overview of the recent progress made for the diagnosis and understanding of fungal lung disease in people with cystic fibrosis (CF), with a focus on Aspergillus fumigatus, the most common filamentous fungus in the CF airway. Currently, the longstanding question of the clinical significance of Aspergillus fumigatus and other fungi in CF respiratory cultures, in the absence of allergy, remains. Clinical criteria and biomarkers are needed to classify fungal lung disease and determine who may warrant therapy.
Recent findings
Several retrospective and prospective studies have descr...
Source: Current Opinion in Pulmonary Medicine - October 6, 2022 Category: Respiratory Medicine Tags: CYSTIC FIBROSIS: Edited by Peter Barry and Barry Plant Source Type: research
Characteristics of annual mold variations and association with childhood allergic symptoms/diseases via combining surveys and home visit measurements
This study aimed to characterize household fungal diversity and its annual temporal and spatial variations. We developed combined cross-sectional survey, repeated air sampling around a year, and DNA sequencing methods. The questionnaire survey was conducted in 2019, and 4943 valid cases were received from parents; a follow-up case-control study (11 cases and 12 controls) was designed, and onsite measurements of indoor environments were repeated in typical summer, transient season, and winter; dust from floor and beddings in children's room were collected and ITS based DNA sequencing of totally 68 samples was conducted. Res...
Source: Cancer Control - September 28, 2022 Category: Cancer & Oncology Authors: Chenqiu Du Baizhan Li Wei Yu Runming Yao Jiao Cai Bicheng Li Yinghui Yao Yujue Wang Min Chen Emmanuel Essah Source Type: research
Introducing biomarkers for invasive fungal disease in haemato-oncology patients: a single-centre experience
Conclusions. Biomarkers can be used safely as part of a multidisciplinary approach to the diagnosis of IFD in neutropaenic haemato-oncology patients. Whilst they do not necessarily result in antifungal therapy being withheld, they can allow more confident diagnosis of IFD and more specific antifungal therapy in selected cases.PMID:35819894 | DOI:10.1099/jmm.0.001564
Source: Journal of Medical Microbiology - July 12, 2022 Category: Microbiology Authors: Anthony W Martinelli Callum B Wright Marta S Lopes Rosemary L Swayne Pramila Krishnamurthy Charles Crawley Ben Uttenthal George Follows Judith Babar Sani H Aliyu David A Enoch Clare R Sander Source Type: research
