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Infectious Disease: Aspergillus
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Total 481 results found since Jan 2013.
LABP-73: A Novel NLRX1 Ligand for the Treatment of Chronic Asthma
NLRX1 is a negative regulatory NOD-like receptor that has previously been shown to be protective against multiple respiratory diseases, including chronic obstructive pulmonary disease and fungal challenge with Aspergillus fumigatus. Activation of NLRX1, with the orally-active, gut-restricted first-in-class therapeutic, NX-13, has previously demonstrated an ability to control immunometabolism and to reduce Th17 differentiation and neutrophil recruitment while providing a favorable tolerability profile in the context of inflammatory bowel disease.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Andrew Leber, Raquel Hontecillas, Nuria Tubau-Juni, Sarah Fitch, Sameeksha Alva, Jyoti Chauhan, Josep Bassaganya-Riera Source Type: research
Aeroallergen sensitivity among children with asthma and its association with asthma control in Sri Lanka
Conclusion: The incidence of aeroallergen sensitization increased in successive cohorts of children with asthma attending a specialist hospital in Sri Lanka in 2013 v 2020. Further research will determine whether this has been associated with changes in the prevalence and severity of asthma.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Gajaweera, H., Jeevandara, C., Malavige, N., Bandara, C., Weerasekara, K. Tags: Paediatric asthma and allergy Source Type: research
M078 allergic bronchopulmonary mycosis in a pediatric patient with primary ciliary dyskinesia
Allergic bronchopulmonary mycosis (ABPM) is typically diagnosed in patients with underlying severe bronchial asthma or cystic fibrosis (CF). ABPM is differentiated from allergic bronchopulmonary aspergillosis (ABPA) by the production of IgE-specific antibodies to a mold other than Aspergillus fumigatus (A. fumigatus).
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: A. Mittman Source Type: research
The LAMMER Kinase, LkhA, Affects Aspergillus fumigatus Pathogenicity by Modulating Reproduction and Biosynthesis of Cell Wall PAMPs
The LAMMER kinase in eukaryotes is a well-conserved dual-specificity kinase. Aspergillus species cause a wide spectrum of diseases called aspergillosis in humans, depending on the underlying immune status of the host, such as allergy, aspergilloma, and invasive aspergillosis. Aspergillus fumigatus is the most common opportunistic fungal pathogen that causes invasive aspergillosis. Although LAMMER kinase has various functions in morphology, development, and cell cycle regulation in yeast and filamentous fungi, its function in A. fumigatus is not known. We performed molecular studies on the function of the A. fumigatus LAMME...
Source: Frontiers in cellular and infection microbiology - October 13, 2021 Category: Microbiology Source Type: research
Role of Aspergillus fumigatus sensitization in Patients with Asthma- COPD Overlap compared to asthma patients
Conclusionsensitization to Aspergillus was more among ACO patients compared to Asthma and control groups.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Analysis of Cross-Reactivity and Allergic Symptoms of 19 Allergens: Results from NHANES 2005 –2006
Conclusion: Species that are biologically close are more likely to have antigen cross-reactivity, while cross-reactivity among different species is common. Different allergens tend to cause different allergic symptoms. Different allergic sites in the body have inconsistent responses to the number of sensitized allergens.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - September 21, 2021 Category: Allergy & Immunology Source Type: research
Aspergillus-related diseases in a cohort of patients with severe asthma: A SANI single-center report
Publication date: July 2021Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 9, Issue 7Author(s): Paolo Solidoro, Stefania Nicola, Irene Ridolfi, Caterina Bucca, Enrico Heffler, Diego Bagnasco, Giorgio Walter Canonica, Francesco Blasi, Pierluigi Paggiaro, Giovanni Rolla, Luisa Brussino
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 7, 2021 Category: Allergy & Immunology Source Type: research
Microbiological profile in chronic granulomatous disease patients in a single Brazilian primary immunodeficiencies center
CONCLUSION: Staphylococcus sp., Staphylococcus aureus, and Aspergillus sp. were the most frequent agents in this cohort. M. tuberculosis should be considered in endemic areas. Detection of infectious agents drives to find adequate treatment and benefits the evolution of patients with CGD.PMID:34224228 | DOI:10.15586/aei.v49i4.202
Source: Allergologia et Immunopathologia - July 5, 2021 Category: Allergy & Immunology Authors: Aim ée Filippini Bifulco Oliveira Antonio Carlos Pastorino Mayra de Barros Dorna Ana Paula Beltran Moschione Castro Jos é Roberto Mendes Pegler Beni Morgenstern Magda Maria Sales Carneiro-Sampaio Source Type: research
