Query: allergy Immmunology

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the official manual book on allergen-immunotherapy in house-dust-mite allergy.
[THE OFFICIAL MANUAL BOOK ON ALLERGEN-IMMUNOTHERAPY IN HOUSE-DUST-MITE ALLERGY]. Arerugi. 2019;68(3):146-150 Authors: Nagata M PMID: 31105110 [PubMed - in process]
Source: Arerugi - May 21, 2019 Category: Allergy & Immunology Authors: Nagata M Tags: Arerugi Source Type: research

Closing the door on social determinants of health and asthma disparities: Not so fast
Publication date: Available online 21 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elizabeth C. Matsui, Craig E. Pollack, Roger D. Peng, Corinne A. Keet
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 21, 2019 Category: Allergy & Immunology Source Type: research

Reply
Publication date: Available online 20 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Theresa W. Guilbert, Robert S. Zeiger, Tmirah Haselkorn, Ahmar Iqbal, Cynthia Alvarez, David R. Mink, Bradley E. Chipps, Stanley J. Szefler
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 21, 2019 Category: Allergy & Immunology Source Type: research

Clinical Drug Diversion Costly to Health Care Organizations
Report finds 47.2 million doses lost due to health care worker misuse and theft in 2018
Source: The Doctors Lounge - Psychiatry - May 21, 2019 Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

Pollen count warning: Forecast today revealed - the worst time to go outside for hay fever
POLLEN COUNT forecast: The Met Office has forecasted hay fever sufferers to endure unwanted symptoms today. This is the worst time to go outside if you have hay fever - it could trigger signs of the allergy, including sneezing and watering eyes.
Source: Daily Express - Health - May 21, 2019 Category: Consumer Health News Source Type: news

New Findings in Pollen-Food Allergy Syndrome New Findings in Pollen-Food Allergy Syndrome
Recent findings have identified new antigens and clarified the pathogenesis of pollen-food allergy syndrome. What are the implications for treatment?Current Opinion in Allergy and Clinical Immunology
Source: Medscape Allergy Headlines - May 21, 2019 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology Journal Article Source Type: news

COPD Exacerbations Associated With Biomass vs Tobacco Smoke COPD Exacerbations Associated With Biomass vs Tobacco Smoke
Might the risk of acute COPD exacerbations differ between biomass smoke and tobacco smoke exposure? In what ways?BMC Pulmonary Medicine
Source: Medscape Allergy Headlines - May 21, 2019 Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news

The Complicated Dance of Infections and Asthma
The interaction between asthma and infections is a complicated one, and that is the focus of this issue of the Immunology and Allergy Clinics of North America. Infections, both viral and bacterial, have been associated with development and exacerbation of asthma, while parasitic infections may actually help protect against asthma. Furthermore, as our drug armamentarium begins to focus on biologics, which can selectively impair components of the immune response, there is concern that treated patients with asthma will be at risk of developing opportunistic infections.
Source: Immunology and Allergy Clinics of North America - May 21, 2019 Category: Allergy & Immunology Authors: Mitchell H. Grayson Tags: Preface Source Type: research

Importance of Virus Characteristics in Respiratory Syncytial Virus-Induced Disease
Severe lower respiratory tract infection in infants and young children is most frequently caused by respiratory syncytial virus (RSV). RSV infects the smallest airways, making breathing difficult and in some infants requiring medical support. Severity is affected by viral dose, infant age, virus genotype, and effectiveness of the innate/adaptive immune responses. Severe disease correlates with later wheezing and asthma in some children. The adaptive immune response is protective but wanes after each infection, likely due to the ability of the RSV NS1/NS2 proteins to inhibit the innate immune response. Several vaccine appro...
Source: Immunology and Allergy Clinics of North America - May 21, 2019 Category: Allergy & Immunology Authors: Homero San-Juan-Vergara, Mark E. Peeples Source Type: research

Lymphocyte Transformation Test (LTT) in Allergy to Benznidazole: A Promising Approach
We report a series of 31 patients (69% women) referred to our Allergy unit with suspected hypersensitivity to Bzn, twenty-three of them with mild reactions and nine of them with severe reactions. LTT with Bzn was performed in 31 patients and in 8 negative controls. LTT was also performed in 25 and 20 of these patients with nifurtimox and Mtn, respectively. Twenty one out of thirty one patients were Bzn prick tested, all negative. We obtained 2/21 positive results on patch tests to Bzn. LTT with Bzn was positive in 22/31 patients (Sensitivity 75.9% and specificity 100%). The test was considered positive with a stimulation i...
Source: Frontiers in Pharmacology - May 21, 2019 Category: Drugs & Pharmacology Source Type: research

Clinical, Immunological, and Genetic Features in Patients with Activated PI3K δ Syndrome (APDS): a Systematic Review
AbstractActivated phosphoinositide 3-kinase delta syndrome (APDS) is a novel primary immunodeficiency (PID) caused by heterozygous gain of function mutations in PI3K δ catalytic p110δ (PIK3CD) or regulatory p85 α (PIK3R1) subunits leading to APDS1 and APDS2, respectively. Patients with APDS present a spectrum of clinical manifestations, particularly recurrent respiratory infections and lymphoproliferation. We searched PubMed, Web of Science, and Scopus databases for APDS patients and screened for eligibility criteria. A total of 243 APDS patients were identified from 55 articles. For all patients, demographic, clinical,...
Source: Clinical Reviews in Allergy and Immunology - May 21, 2019 Category: Allergy & Immunology Source Type: research

Stress, Itch Sensation, and Scratching in Atopic Dermatitis Stress, Itch Sensation, and Scratching in Atopic Dermatitis
This paper explores the interrelationship of acute stress, itch, and scratching in patients with atopic dermatitis, providing new insights on the mechanism of stress-related exacerbation of itch.The British Journal of Dermatology
Source: Medscape Allergy Headlines - May 20, 2019 Category: Allergy & Immunology Tags: Dermatology Journal Article Source Type: news

May 8, 2019: Meeting of the Pulmonary-Allergy Drugs Advisory Committee Meeting Announcement - 05/08/2019 - 05/08/2019
May 8, 2019: Meeting of the Pulmonary-Allergy Drugs Advisory Committee Meeting Announcement
Source: FDA Center for Drug Evaluation and Research - What's New - May 20, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements
MicroRNA-21 (miR-21), probably one of the most studied miRNAs to date, is found pleiotropic in various biological events. Its emerging role in pulmonary remodeling has attracted extensive attention. This revie...
Source: Allergy, Asthma and Clinical Immunology - May 20, 2019 Category: Allergy & Immunology Authors: Congshan Jiang, Yuanxu Guo, Hongchuan Yu, Shemin Lu and Liesu Meng Tags: Review Source Type: research

The Distinguishing Clinical Features of Nonallergic Rhinitis Patients.
CONCLUSION: Patients who were older, without asthma, and lacked an inhalant allergy trigger were more likely to have true NAR. Environmental triggers are not distinguishing features of NAR. This may be used as a guide to identify rhinitis patients whose symptoms are truly nonallergic etiology compared to those with falsely negative systemic allergy assessment but may still need management for LAR. PMID: 31106562 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - May 20, 2019 Category: ENT & OMF Authors: Hamizan AW, Azer M, Alvarado R, Earls P, Barham HP, Tattersall J, Rimmer J, Kalish L, Sewell WA, Harvey R Tags: Am J Rhinol Allergy Source Type: research

Correction to: Genetically engineered probiotic Saccharomyces cerevisiae strains mature human dendritic cells and stimulate gag-specific memory CD8+ T cells ex vivo.
Abstract In the Funding section, the following statement is missing: The MACS cohort study was supported by the NIH, National Institute of Allergy and Infectious Diseases grant U01-AI35041. PMID: 31106390 [PubMed - as supplied by publisher]
Source: Applied Microbiology and Biotechnology - May 20, 2019 Category: Microbiology Authors: Palma ML, Garcia-Bates TM, Martins FS, Douradinha B Tags: Appl Microbiol Biotechnol Source Type: research

Guidelines on management of atopic dermatitis in India: An evidence-based review and an expert consensus
Conclusion: These guidelines should form a reference for the management of patients with AD in an evidence-based manner.
Source: Indian Journal of Dermatology - May 20, 2019 Category: Dermatology Authors: Murlidhar Rajagopalan Abhishek De Kiran Godse DS Krupa Shankar Vijay Zawar Nidhi Sharma Samipa Mukherjee Aarti Sarda Sandipan Dhar Source Type: research

The amino acid sensor GCN2 controls Th9 cells and allergic airway inflammation
The amino acid sensor GCN2 controls Th9 cell differentiation through metabolic pathway and could be a promising molecular target to treat allergic airway inflammation.
Source: Journal of Allergy and Clinical Immunology - May 20, 2019 Category: Allergy & Immunology Authors: Peng Wang, Yana Xu, Jiayu Zhang, Lu Shi, Tong Lei, Yangxiao Hou, Zhongbing Lu, Yong Zhao Source Type: research

Pollen-sensitive individuals have specific psychological profiles
AbstractIt was shown that allergic diseases can have a psychosomatic component, and it may be important to consider it in the allergy treatment. So the aim of the study was to determine the presence of a leading psycho-type in a group of subjects with a confirmed diagnosis of seasonal allergy in order to improve both medical care and information delivery to patients. The study was carried out among adult men and women using the MMPI (The Minnesota Multiphasic Personality Inventory) methodology. It involved 86 volunteers. Twenty-five of them constituted the control group of 13 women and 12 men, who previously had never been...
Source: Aerobiologia - May 20, 2019 Category: Environmental Health Source Type: research

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis.
Conclusions: The nasal eosinophil count was significantly associated with protein-corrected EPO. PMID: 31096743 [PubMed - as supplied by publisher]
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Pollen count warning: Forecast today revealed - how to avoid hay fever symptoms
POLLEN COUNT UK forecast: Hay fever patients can expect some unwanted allergy symptoms today . But how can you lower your risk of allergic rhinitis signs? This is how to prevent hay fever symptoms.
Source: Daily Express - Health - May 19, 2019 Category: Consumer Health News Source Type: news

Britain's five-a-day obsession is triggering a frightening new allergy 
The British public are now chugging 898 million litres of fruit juices and smoothies each year, according to the British Soft Drinks Association. But experts warn fruit and veg obsession has a cost.
Source: the Mail online | Health - May 18, 2019 Category: Consumer Health News Source Type: news

Evaluation of Prehospital Management in a Canadian Emergency Department Anaphylaxis Cohort
ConclusionsPrompt epinephrine treatment is crucial. Use of antihistamines in conjunction with epinephrine may reduce the risk of uncontrolled reactions (administration of 2 or more doses of epinephrine in the ED), although our findings do not support the use of corticosteroids.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 18, 2019 Category: Allergy & Immunology Source Type: research

Fish-derived low molecular weight components modify bronchial epithelial barrier properties and release of pro-inflammatory cytokines
Publication date: August 2019Source: Molecular Immunology, Volume 112Author(s): Tanja Kalic, Isabella Ellinger, Sandip D. Kamath, Chiara Palladino, Vanessa Mayr, Angelika Tscheppe, Thimo Ruethers, Eva E. Waltl, Verena Niederberger, Nina Lengger, Christian Radauer, Christine Hafner, Andreas L. Lopata, Merima Bublin, Heimo BreitenederAbstractThe prevalence of fish allergy among fish-processing workers is higher than in the general population, possibly due to sensitization via inhalation and higher exposure. However, the response of the bronchial epithelium to fish allergens has never been explored. Parvalbumins (PVs) from bo...
Source: Molecular Immunology - May 18, 2019 Category: Allergy & Immunology Source Type: research

CMS Reverses Course: ' Protected ' Drug Classes Still Covered CMS Reverses Course: ' Protected ' Drug Classes Still Covered
But the agency is reaffirming that step therapy is allowed for Part B drugs under Medicare Advantage.Medscape Medical News
Source: Medscape Allergy Headlines - May 18, 2019 Category: Allergy & Immunology Tags: Family Medicine/Primary Care News Source Type: news

Ana o 3-specific IgE is a predictive marker for cashew oral food challenge failure
Publication date: Available online 17 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Sakura Sato, Robert Movérare, Yukihiro Ohya, Komei Ito, Mizuho Nagao, Magnus P. Borres, Motohiro Ebisawa
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 17, 2019 Category: Allergy & Immunology Source Type: research

Innovations in Health Care Delivery: Drug Allergy
Publication date: Available online 17 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Allison Ramsey, Aziz SheikhAbstractThis review focuses on advances in health information technology (HIT) in the detection, diagnosis, and management of drug allergy. The data regarding the use of electronic health records (EHR) and social media for the detection of drug allergy is reviewed, along with predictive algorithms and clinical decision support systems for drug allergy diagnosis. Drug allergy pathways, algorithms, CDSS (computerized decision support systems), and CPOE (computerized physician ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 17, 2019 Category: Allergy & Immunology Source Type: research

A comparison of leukotriene receptor antagonists to low-dose inhaled corticosteroids in elderly mild asthmatics
ConclusionThe effectiveness of LTRAs was not different from that of low-dose ICSs regarding the risk of asthma exacerbation in elderly asthma patients in real-world settings. Given the practical benefits gained from convenient administration, LTRA can be considered a reasonable alternative first-line therapy for elderly patients with mild asthma.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 17, 2019 Category: Allergy & Immunology Source Type: research

Distribution and Determinants of < b > < i > Dermatophagoides < /i > < /b > Mites Sensitization ofAllergic Rhinitis and Allergic Asthma in China
Conclusion: These findings may inform clinicians of the strategies for the prevention ofDermatophagoides sensitization and may be of benefit to the future clinical management of allergic diseasesassociated with sensitization toDermatophagoides mites.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - May 17, 2019 Category: Allergy & Immunology Source Type: research

Anaphylaxis in pregnancy in the USA: Risk factors and temporal trends using national routinely collected data
ConclusionDespite increased rates of caesarean delivery in USA and consequent drug administration, there was no evidence of an increasing trend in anaphylaxis. Caesarean delivery and prior history of an allergic reaction allow the identification of women at risk of anaphylaxis. Not all women had clear risk factors and preparations should always be in place to ensure timely management if this uncommon event occurs.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 17, 2019 Category: Allergy & Immunology Source Type: research

Successful rapid push subcutaneous desensitization in a patient with delayed local hypersensitivity reactions to immunoglobulins
Publication date: Available online 16 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rohit R. Ghurye, Philip Bright, David Lowe, Matthew S. Buckland
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 17, 2019 Category: Allergy & Immunology Source Type: research

Factors Associated with the Development of Immune Tolerance in Children with Cow ’s Milk Allergy
Conclusions: Tolerance acquisition is faster in non-IgE-mediated CMA subjects and in those who received casein hydrolysate with LGG.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - May 17, 2019 Category: Allergy & Immunology Source Type: research

Cow's milk allergy: 'Going to a coffee shop could kill my child'
Five-year-old Evie Kinsella's cow's milk allergy is so severe she reacts to milk particles in the air.
Source: BBC News | Health | UK Edition - May 17, 2019 Category: Consumer Health News Source Type: news

Beer allergy: when malt is the culprit
Beer is the most widely consumed alcoholic beverage in the world and beer allergy is rare1-3. The fundamental ingredients of beer according to the Bavarian Purity Law include barley malt, hops, yeast and water but each individual beer may differ in malt content and brewing procedures4. Malt is obtained by roasting germinated cereal and is essential to beer flavouring3. In beer-allergic subjects the most frequent allergenic sources involved are cereals, particularly barley malt2 and wheat3. Pan-allergens, namely lipid transfer proteins (LTP) have been also involved5.
Source: Annals of Allergy, Asthma and Immunology - May 17, 2019 Category: Allergy & Immunology Authors: Maria Jo ão Vasconcelos, Jenny Badas, Borja Bartolomé, Alice Coimbra, Diana Silva Tags: Letters Source Type: research

Do no harm: Natural language processing of social media supports safety of aseptic allergen immunotherapy procedures
Millions of Americans receive allergen immunotherapy (AIT) or “allergy shots” annually to address allergic rhinitis.1 AIT treatments have been provided for more than a century and until recently had been delivered by using an aseptic technique.1 In a prior retrospective study, more than 3000 patients with no AIT-associated skin and soft-tissue infections ( SSTIs) were identified.1 However, recently, there has been renewed concern about preparation at compounding pharmacies that have led to infection outbreaks.
Source: Journal of Allergy and Clinical Immunology - May 17, 2019 Category: Allergy & Immunology Authors: Valerie G. Press, Sharmilee M. Nyenhuis Tags: Editorial Source Type: research

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model.
Abstract Drug allergies occur when hapten-like drug metabolites conjugated to serum proteins, through their interactions with specific IgE, trigger allergic reactions that can be life threatening. A molecule termed covalent heterobivalent inhibitor (cHBI) was designed to specifically target drug hapten-specific IgE to prevent it from binding drug-haptenated serum proteins. cHBI binds the two independent sites on a drug hapten-specific Ab and covalently conjugates only to the specific IgE, permanently inhibiting it. The cHBI design was evaluated via ELISA to measure cHBI-IgE binding, degranulation assays of rat bas...
Source: Journal of Immunology - May 17, 2019 Category: Allergy & Immunology Authors: Deak PE, Kim B, Koh B, Qayum AA, Kiziltepe T, Kaplan MH, Bilgicer B Tags: J Immunol Source Type: research

Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy
In this study, we investigated the presence of α-gal in four tick species: the lone-star tick (Amblyomma americanum), the Gulf-Coast tick (Amblyomma maculatum), the American dog tick (Dermacentor variabilis), and the black-legged tick (Ixodes scapularis) by using a combination of immunoproteomic approach and , carbohydrate analysis., and basophil activation approaches. Using aAnti-α-gal antibodies, α-gal was identified α-gal in the salivary glands of both Am. americanum and Ix. scapularis, while Am. maculatum and De. variabilis appeared to lack the sugarcarbohydrate. PNGase F treatment confirmed the deglycosylation of ...
Source: Frontiers in Immunology - May 17, 2019 Category: Allergy & Immunology Source Type: research

Travelers' Diarrhea: A Clinical Review.
CONCLUSION: Although travelers' diarrhea is usually self-limited, many travelers prefer expedient relief of the diarrhea, especially when they are traveling for extended periods by air or ground. Judicious use of an antimotility agent and antimicrobial therapy reduces the duration and severity of diarrhea. PMID: 31084597 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - May 16, 2019 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Allergen-specific IgE to recombinant latex allergens in occupational allergy diagnostics.
CONCLUSIONS: Test for recombinant latex allergens is much more accurate in recognition of latex allergy than test for latex extract, which seems to produce false-positive results in patients with pollen allergy. The measurements of sIgE against recombinant latex allergens Hev b 6.01, 6.02, 5, and 8 are useful in differentiating OA from WEA. PMID: 31090202 [PubMed - as supplied by publisher]
Source: Journal of Occupational Health - May 16, 2019 Category: Occupational Health Tags: J Occup Health Source Type: research

Prevention of allergy with diverse and healthy microbiota: an update
Purpose of review Microbiota consist of symbiotic microscopic neighbors that interact on and within our bodies in diverse and incompletely understood ways throughout our lifetime. Though various associations with allergic disease have been described, clear effective therapeutic interventions to prevent allergy have been elusive. Recent findings The human microbiome is influenced by multiple factors, including: mode of infant delivery (vaginal vs. cesarean section), breastfeeding, diet, presence of siblings and pets, exposure to antibiotics and other medications (particularly antacids), lifestyle, and developmental con...
Source: Current Opinion in Pediatrics - May 16, 2019 Category: Pediatrics Tags: OFFICE PEDIATRICS: Edited by Henry H. Bernstein Source Type: research

Hymenoptera-venom allergy in a single-center Israeli cohort: Clinical and laboratory characteristics
Publication date: Available online 14 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Alon Y. Hershko, Noa Shaharabani, Yossi Rosman, Keren Meir-Shafrir, Idith Lachover-Roth, Anat Cohen Engler, Yossi Mekori, Ronit Confino-Cohen
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Factors Associated with Physician-Patient Discordance in the Perception of Asthma Control
ConclusionThe subjective perception of the physicians did not show a good agreement with the patients’ asthma control based on validated ACQ scores, with increased rates of discordance among patients whose asthma was not well-controlled and patients who had not received lung function assessment.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Availability of Mental Health Services for Patients with Food Allergy
Publication date: Available online 14 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Linda Herbert, Mary Jane Marchisotto, Hemant Sharma, Ruchi Gupta, Lucy A. Bilaver
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Galectin-7 as a potential biomarker of Stevens–Johnson syndrome/ toxic epidermal necrolysis: Identification by targeted proteomics using causative drug-exposed peripheral blood cells
Publication date: Available online 14 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Natsumi Hama, Keiko Nishimura, Akito Hasegawa, Akihiko Yuki, Hideaki Kume, Jun Adachi, Manao Kinoshita, Youichi Ogawa, Saeko Nakajima, Takashi Nomura, Hideaki Watanabe, Yoshiko Mizukawa, Takeshi Tomonaga, Hiroshi Shimizu, Riichiro Abe
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Exploring the utility of non-invasive Type-2 inflammatory markers for prediction of severe asthma exacerbations in children and adolescents
ConclusionBlood eosinophils and other non-invasive markers of Type-2 inflammation may be useful in the clinical assessment of children and adolescents with asthma. However, features of Type-2 inflammation vary by age. Whether children and adolescents also respond differently to management of Type-2 inflammation is unclear and warrants further evaluation.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Cross-reactivity and tolerability of celecoxib in adult patients with NSAID hypersensitivity
Publication date: Available online 14 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Lily Li, Tanya Laidlaw
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Comparison of practice patterns among Canadian allergists before and after NIAID guideline recommendations
Publication date: Available online 14 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elissa M. Abrams, Lianne Soller, Alexander G. Singer, David M. Fleischer, Matthew Greenhawt, Edmond S. Chan
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 15, 2019 Category: Allergy & Immunology Source Type: research

Impact of Allergic Rhinitis on Nasal Mucociliary Clearance Time in Children
Conclusions: AR affects the mucociliary clearance in children, and its deterioration is related to more severe rhinitis with higher intensity of local nasal inflammation, reflected in nasal smear eosinophilia.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - May 15, 2019 Category: Allergy & Immunology Source Type: research

The Heterogeneous Pathogenesis of Selective Immunoglobulin A Deficiency
Selective immunoglobulin A deficiency (SIgAD) is the most prevalent type of primary immunodeficiency disorder. The phenotypic feature of SIgAD is related to a defect in B lymphocyte differentiation into plasma cell-producing immunoglobulin A (IgA). In this review, we summarize the recent advances in this regard. Genetic (including major histocompatibility complex [MHC] and non-MHC genes), immunologic (including B and T lymphocyte subsets abnormality), cytokines/chemokines and their related receptors, apoptosis and microbiota defects are reviewed. The mechanisms leading to SIgAD are most likely multifactorial and it can be ...
Source: International Archives of Allergy and Immunology - May 15, 2019 Category: Allergy & Immunology Source Type: research

The Effect of Antileukotrienes on the Results of Postoperative Treatment of Paranasal Sinuses in Patients with Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease
Conclusions: The results suggest comparable efficacy of treatment with nasal steroids and antileukotrienes in patients with NERD after ESS. Treatment with montelukast and mometasone has not been shown to be superior to both drugs administered separately.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - May 15, 2019 Category: Allergy & Immunology Source Type: research