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Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research
Immune Dysfunction from Radiation Exposure
Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-22-00197.1. Online ahead of print.ABSTRACTExposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced resistance to infections and hemorrhage. Besides these acute effects, tissue damage from radiation can trigger inflammatory responses, leading to progressive and chronic tissue damage by radiation-induced loss of immune cell types that are required for resolving tissue injuries. Understanding the mechanisms involved in radiation-induced immune system injury and repair will provide new insig...
Source: Radiation Research - September 13, 2023 Category: Physics Authors: David R Cassatt Thomas A Winters Mercy PrabhuDas Source Type: research
FDA Panel Favors Dropping OTC Decongestant
(MedPage Today) -- Hundreds of allergy and cold medicines on retail shelves contain oral phenylephrine, with brands including Sudafed PE and Suphedrine PE totaling over a billion dollars in sales each year. However, that oral decongestant --...
Source: MedPage Today Allergy - September 13, 2023 Category: Allergy & Immunology Source Type: news
